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Gene Dmel\CG6356

General Information
Symbol	Dmel\CG6356	Species	D. melanogaster
Name		Annotation symbol	CG6356
Feature type	protein_coding_gene	FlyBase ID	FBgn0039178
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	95F9-95F9	Sequence location	3R:20,109,856..20,114,343 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG6356 (FBgn0039178). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: secondary active organic cation transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: General substrate transporter; Major facilitator superfamily domain; Major facilitator superfamily domain, general substrate transporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 06-12 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system. Comments on Affy2 ProbeSet: ProbeSet 1624448_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG6356. Gene sequence location is 3R:20109856..20114343.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN30028 HFA16026
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 95F9-95F9   Limits computationally determined from genome sequence between P{PZ}Syx1A06737&P{PZ}Syx1A10660 and P{PZ}crb07207&P{PZ}BRWD305842
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG6356 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG6356-RA FBtr0084601  NM_142983   2712   570
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG6356-PA   FBpp0083985   62.9   570   8.07     NP_651240   AAF56273
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Major facilitator superfamily domain, general substrate transporter (IPR016196) General substrate transporter (IPR005828) Major facilitator superfamily domain (IPR020846)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF56273   AI062711   AI062781   AY118724 AAM50584   BI165071   BI172160   BI374599   BT044239   CO180336   CO182510   CO189333   CO269773   CO287603   CO289514   CO312619   EC058564   EC087938   EC201712   EC208751   EC219847   EC229784   EC254855
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8MSK7 Q9VCA0
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039178    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039178 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 06-12 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039178 expression level Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    53 embryo 04-06hr    159 embryo 06-08hr    1197 embryo 08-10hr    1699 embryo 10-12hr    1065 embryo 12-14hr    1034 embryo 14-16hr    833 embryo 16-18hr    570 embryo 18-20hr    1307 embryo 20-22hr    1283 embryo 22-24hr    1616 larva L1    1572 larva L2    413 larva L3 12hr old    304 larva L3 puffstage 1-2    1041 larva L3 puffstage 3-6    2186 larva L3 puffstage 7-9    1835 white prepupae new    614 white prepupae 12hr    2207 white prepupae 24hr    1430 pupae 2d postWPP    2387 pupae 3d postWPP    1506 pupae 4d postWPP    1712 adult male 01day    739 adult male 05day    655 adult male 30day    553 adult female 01day    381 adult female 05day    205 adult female 30day    121 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    53 embryo 04-06hr  (159) embryo 06-08hr  (1197) embryo 08-10hr  (1699) embryo 10-12hr  (1065) embryo 12-14hr  (1034) embryo 14-16hr  (833) embryo 16-18hr  (570) embryo 18-20hr  (1307) embryo 20-22hr  (1283) embryo 22-24hr  (1616) larva L1  (1572) larva L2  (413) larva L3 12hr old  (304) larva L3 puffstage 1-2  (1041) larva L3 puffstage 3-6  (2186) larva L3 puffstage 7-9  (1835) white prepupae new  (614) white prepupae 12hr  (2207) white prepupae 24hr  (1430) pupae 2d postWPP  (2387) pupae 3d postWPP  (1506) pupae 4d postWPP  (1712) adult male 01day  (739) adult male 05day  (655) adult male 30day  (553) adult female 01day  (381) adult female 05day  (205) adult female 30day  (121) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    53 embryo 04-06hr    159 embryo 06-08hr    1197 embryo 08-10hr  (1699) embryo 10-12hr    1065 embryo 12-14hr    1034 embryo 14-16hr    833 embryo 16-18hr    570 embryo 18-20hr    1307 embryo 20-22hr    1283 embryo 22-24hr  (1616) larva L1  (1572) larva L2    413 larva L3 12hr old    304 larva L3 puffstage 1-2    1041 larva L3 puffstage 3-6  (2186) larva L3 puffstage 7-9  (1835) white prepupae new    614 white prepupae 12hr  (2207) white prepupae 24hr  1430 pupae 2d postWPP  (2387) pupae 3d postWPP  1506 pupae 4d postWPP  (1712) adult male 01day    739 adult male 05day    655 adult male 30day    553 adult female 01day    381 adult female 05day    205 adult female 30day    121 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    53 embryo 04-06hr    159 embryo 06-08hr    1197 embryo 08-10hr    1699 embryo 10-12hr    1065 embryo 12-14hr    1034 embryo 14-16hr    833 embryo 16-18hr    570 embryo 18-20hr    1307 embryo 20-22hr    1283 embryo 22-24hr    1616 larva L1    1572 larva L2    413 larva L3 12hr old    304 larva L3 puffstage 1-2    1041 larva L3 puffstage 3-6    2186 larva L3 puffstage 7-9    1835 white prepupae new    614 white prepupae 12hr    2207 white prepupae 24hr    1430 pupae 2d postWPP    2387 pupae 3d postWPP    1506 pupae 4d postWPP    1712 adult male 01day    739 adult male 05day    655 adult male 30day    553 adult female 01day    381 adult female 05day    205 adult female 30day    121 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    53 embryo 04-06hr    159 embryo 06-08hr    1197 embryo 08-10hr    1699 embryo 10-12hr    1065 embryo 12-14hr    1034 embryo 14-16hr    833 embryo 16-18hr    570 embryo 18-20hr    1307 embryo 20-22hr    1283 embryo 22-24hr    1616 larva L1    1572 larva L2    413 larva L3 12hr old    304 larva L3 puffstage 1-2    1041 larva L3 puffstage 3-6    2186 larva L3 puffstage 7-9    1835 white prepupae new    614 white prepupae 12hr    2207 white prepupae 24hr    1430 pupae 2d postWPP    2387 pupae 3d postWPP    1506 pupae 4d postWPP    1712 adult male 01day    739 adult male 05day    655 adult male 30day    553 adult female 01day    381 adult female 05day    205 adult female 30day    121 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039178 expression level Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    53 embryo 04-06hr    159 embryo 06-08hr    1197 embryo 08-10hr    1699 embryo 10-12hr    1065 embryo 12-14hr    1034 embryo 14-16hr    833 embryo 16-18hr    570 embryo 18-20hr    1307 embryo 20-22hr    1283 embryo 22-24hr    1616 larva L1    1572 larva L2    413 larva L3 12hr old    304 larva L3 puffstage 1-2    1041 larva L3 puffstage 3-6    2186 larva L3 puffstage 7-9    1835 white prepupae new    614 white prepupae 12hr    2207 white prepupae 24hr    1430 pupae 2d postWPP    2387 pupae 3d postWPP    1506 pupae 4d postWPP    1712 adult male 01day    739 adult male 05day    655 adult male 30day    553 adult female 01day    381 adult female 05day    205 adult female 30day    121 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    53 embryo 04-06hr  (159) embryo 06-08hr  (1197) embryo 08-10hr  (1699) embryo 10-12hr  (1065) embryo 12-14hr  (1034) embryo 14-16hr  (833) embryo 16-18hr  (570) embryo 18-20hr  (1307) embryo 20-22hr  (1283) embryo 22-24hr  (1616) larva L1  (1572) larva L2  (413) larva L3 12hr old  (304) larva L3 puffstage 1-2  (1041) larva L3 puffstage 3-6  (2186) larva L3 puffstage 7-9  (1835) white prepupae new  (614) white prepupae 12hr  (2207) white prepupae 24hr  (1430) pupae 2d postWPP  (2387) pupae 3d postWPP  (1506) pupae 4d postWPP  (1712) adult male 01day  (739) adult male 05day  (655) adult male 30day  (553) adult female 01day  (381) adult female 05day  (205) adult female 30day  121 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    53 embryo 04-06hr    159 embryo 06-08hr    1197 embryo 08-10hr  1699 embryo 10-12hr    1065 embryo 12-14hr    1034 embryo 14-16hr    833 embryo 16-18hr    570 embryo 18-20hr    1307 embryo 20-22hr    1283 embryo 22-24hr  1616 larva L1  1572 larva L2    413 larva L3 12hr old    304 larva L3 puffstage 1-2    1041 larva L3 puffstage 3-6  2186 larva L3 puffstage 7-9  1835 white prepupae new    614 white prepupae 12hr  2207 white prepupae 24hr  1430 pupae 2d postWPP  2387 pupae 3d postWPP  1506 pupae 4d postWPP  1712 adult male 01day    739 adult male 05day    655 adult male 30day    553 adult female 01day    381 adult female 05day    205 adult female 30day    121 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    53 embryo 04-06hr    159 embryo 06-08hr    1197 embryo 08-10hr    1699 embryo 10-12hr    1065 embryo 12-14hr    1034 embryo 14-16hr    833 embryo 16-18hr    570 embryo 18-20hr    1307 embryo 20-22hr    1283 embryo 22-24hr    1616 larva L1    1572 larva L2    413 larva L3 12hr old    304 larva L3 puffstage 1-2    1041 larva L3 puffstage 3-6    2186 larva L3 puffstage 7-9    1835 white prepupae new    614 white prepupae 12hr    2207 white prepupae 24hr    1430 pupae 2d postWPP    2387 pupae 3d postWPP    1506 pupae 4d postWPP    1712 adult male 01day    739 adult male 05day    655 adult male 30day    553 adult female 01day    381 adult female 05day    205 adult female 30day    121 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    53 embryo 04-06hr    159 embryo 06-08hr    1197 embryo 08-10hr    1699 embryo 10-12hr    1065 embryo 12-14hr    1034 embryo 14-16hr    833 embryo 16-18hr    570 embryo 18-20hr    1307 embryo 20-22hr    1283 embryo 22-24hr    1616 larva L1    1572 larva L2    413 larva L3 12hr old    304 larva L3 puffstage 1-2    1041 larva L3 puffstage 3-6    2186 larva L3 puffstage 7-9    1835 white prepupae new    614 white prepupae 12hr    2207 white prepupae 24hr    1430 pupae 2d postWPP    2387 pupae 3d postWPP    1506 pupae 4d postWPP    1712 adult male 01day    739 adult male 05day    655 adult male 30day    553 adult female 01day    381 adult female 05day    205 adult female 30day    121 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0039178    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0039178 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0039178 expression level Tissue   Expression Level Larval Central Nervous System    114.35 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    908.1 Larval Salivary Gland no informative data Larval Trachea    6.3 Larval Carcass no informative data Adult Head    126 Adult Eye    74.6 Adult Brain    230.7 Adult Thoracic-Abdominal Ganglion    431.4 Adult Crop    6.5 Adult Midgut    8.6 Adult Hindgut    6.2 Adult Malpighian Tubules    2.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    3.2 Adult VirginFemale Spermatheca    2.3 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    2.6 Adult Testis no informative data Adult Male Accessory Gland    6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    114.35 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body  (908.1) Larval Salivary Gland no informative data Larval Trachea    6.3 Larval Carcass no informative data Adult Head    126 Adult Eye    74.6 Adult Brain    230.7 Adult Thoracic-Abdominal Ganglion    431.4 Adult Crop    6.5 Adult Midgut    8.6 Adult Hindgut    6.2 Adult Malpighian Tubules    2.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    3.2 Adult VirginFemale Spermatheca    2.3 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    2.6 Adult Testis no informative data Adult Male Accessory Gland    6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    114.35 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    908.1 Larval Salivary Gland no informative data Larval Trachea    6.3 Larval Carcass no informative data Adult Head    126 Adult Eye    74.6 Adult Brain    230.7 Adult Thoracic-Abdominal Ganglion    431.4 Adult Crop    6.5 Adult Midgut    8.6 Adult Hindgut    6.2 Adult Malpighian Tubules    2.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    3.2 Adult VirginFemale Spermatheca    2.3 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    2.6 Adult Testis no informative data Adult Male Accessory Gland    6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    114.35 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    908.1 Larval Salivary Gland no informative data Larval Trachea    6.3 Larval Carcass no informative data Adult Head    126 Adult Eye    74.6 Adult Brain    230.7 Adult Thoracic-Abdominal Ganglion    431.4 Adult Crop    6.5 Adult Midgut    8.6 Adult Hindgut    6.2 Adult Malpighian Tubules    2.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    3.2 Adult VirginFemale Spermatheca    2.3 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    2.6 Adult Testis no informative data Adult Male Accessory Gland    6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0039178 expression level Tissue   Expression Level Larval Central Nervous System    114.35 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    908.1 Larval Salivary Gland no informative data Larval Trachea    6.3 Larval Carcass no informative data Adult Head    126 Adult Eye    74.6 Adult Brain    230.7 Adult Thoracic-Abdominal Ganglion    431.4 Adult Crop    6.5 Adult Midgut    8.6 Adult Hindgut    6.2 Adult Malpighian Tubules    2.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    3.2 Adult VirginFemale Spermatheca    2.3 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    2.6 Adult Testis no informative data Adult Male Accessory Gland    6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    114.35 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body  (908.1) Larval Salivary Gland no informative data Larval Trachea    6.3 Larval Carcass no informative data Adult Head    126 Adult Eye    74.6 Adult Brain    230.7 Adult Thoracic-Abdominal Ganglion    431.4 Adult Crop    6.5 Adult Midgut    8.6 Adult Hindgut    6.2 Adult Malpighian Tubules    2.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    3.2 Adult VirginFemale Spermatheca    2.3 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    2.6 Adult Testis no informative data Adult Male Accessory Gland    6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    114.35 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    908.1 Larval Salivary Gland no informative data Larval Trachea    6.3 Larval Carcass no informative data Adult Head    126 Adult Eye    74.6 Adult Brain    230.7 Adult Thoracic-Abdominal Ganglion    431.4 Adult Crop    6.5 Adult Midgut    8.6 Adult Hindgut    6.2 Adult Malpighian Tubules    2.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    3.2 Adult VirginFemale Spermatheca    2.3 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    2.6 Adult Testis no informative data Adult Male Accessory Gland    6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    114.35 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    908.1 Larval Salivary Gland no informative data Larval Trachea    6.3 Larval Carcass no informative data Adult Head    126 Adult Eye    74.6 Adult Brain    230.7 Adult Thoracic-Abdominal Ganglion    431.4 Adult Crop    6.5 Adult Midgut    8.6 Adult Hindgut    6.2 Adult Malpighian Tubules    2.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    3.2 Adult VirginFemale Spermatheca    2.3 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    2.6 Adult Testis no informative data Adult Male Accessory Gland    6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body     Larval Salivary Gland no informative data Larval Trachea     Larval Carcass no informative data Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca no informative data Adult Ovary     Adult Testis no informative data Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    126   NA  Eye    74.6   NA  Brain    230.7   114.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    431.4   NA  Crop    6.5   no informative data  Midgut    8.6   no informative data  Hindgut    6.2   no informative data  Malpighian Tubules    2.8   908.1  Fat Body    no informative data   no informative data  Salivary Gland    no informative data   NA  Heart    3.2   6.3  Trachea    NA   NA  VirginFemale Spermatheca    2.3   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    2.6   NA  Testis    no informative data   NA  Male Accessory Gland    6   no informative data  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_25
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039178 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6356-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG6356GD12814 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG6356 Class Mutagen Stocks Known lesion CG6356MI02777 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG6356 Class Mutagen Stocks Known lesion CG6356GD12814 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG6356JF03173 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG6356KK110028 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6199 (Ryder, 2004.4.26) Df(3R)Exel8178 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12814} NA P{KK110028} NA P{TRiP.JF03173} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}CG6356MI02777 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
secondary active organic cation transmembrane transporter activity inferred from sequence or structural similarity with EMBL:AB016257 (FlyBase, 1992-)
Biological Process
CV term Evidence References
transmembrane transport inferred from electronic annotation with InterPro:IPR005828 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR005828 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG6356 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0039178
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16122 Dere\GG11274 Dgri\GH14187 Dmoj\GI22097 Dper\GL23364 Dpse\GA19535 Dsec\GM26583 Dsim\GD21085 Dvir\GJ24211 Dwil\GK11739 Dyak\GE23467
Curated drosophilid orthologs	Dpse\GA19535
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL012444-PA Aedes aegypti (mosquito) AGAP003303-PA Anopheles gambiae (mosquito) XP_393846.3 Apis mellifera (honey bee) XP_001945084.1 Acyrthosiphon pisum (pea aphid) CPIJ001659 Culex pipens (mosquito) XP_001607406.1 Nasonia vitripennis (wasp) PHUM005157-PA Pediculus humanus (human body louse) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11810 FBgn0240648 FBgn0213750 FBgn0211294 FBgn0192539 FBgn0181436 FBgn0079531 FBgn0160954 FBgn0144826 FBgn0121663 FBgn0103575 FBgn0093144 CPIJ001659 ACYPI004070 ACYPI003393 GB11834 AGAP003303 AAEL012444 PHUM605140
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	28745 y1 v1; P{TRiP.JF03173}attP2 36046 y1 w*; Mi{MIC}CG6356MI02777
VDRC	v101866 P{KK110028}VIE-260B v23013 w1118; P{GD12814}v23013
Genomic Clones ( 1 )
	BACR04E17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 20 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH02014
Other clones	FI05810
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH02114 RE04878 RE14436 RE62234
Other clones	80609 105042 CK01.54A.E5 CK01.82D.G12 CK01.91A.E11 CK01.129B.H10 EC01425 EC22902 EC254855 EK044019 EK066258 EK071220 EK095861 EK229524
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039178 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42893
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142983 RefSeq (Proteins) • NP_651240 DDBJ / EMBL / GenBank • AAF56273 AAM50584 AI062711 AY118724 Entrez Gene - A searchable database of RefSeq genes. • 42893 UniProtKB/TrEMBL • Q8MSK7 Q9VCA0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Major facilitator superfamily domain, general substrate transporter (IPR016196) General substrate transporter (IPR005828) Major facilitator superfamily domain (IPR020846)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0039178 DRSC - Results from RNAi screens. • FBgn0039178 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039178 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6356-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039178 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42893 InParanoid A subset of ortholog calls from InParanoid. • AAEL012444-PA Aedes aegypti (mosquito) AGAP003303-PA Anopheles gambiae (mosquito) XP_393846.3 Apis mellifera (honey bee) XP_001945084.1 Acyrthosiphon pisum (pea aphid) CPIJ001659 Culex pipens (mosquito) XP_001607406.1 Nasonia vitripennis (wasp) PHUM005157-PA Pediculus humanus (human body louse) modMine - Data generated by the modENCODE project. • FBgn0039178 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11810 FBgn0240648 FBgn0213750 FBgn0211294 FBgn0192539 FBgn0181436 FBgn0079531 FBgn0160954 FBgn0144826 FBgn0121663 FBgn0103575 FBgn0093144 CPIJ001659 ACYPI004070 ACYPI003393 GB11834 AGAP003303 AAEL012444 PHUM605140
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG6356 (Keleman et al., 2009.8.5, Perkins et al., 2009)
Name Synonym
Secondary FlyBase IDs
References ( 14 )
Supplementary material	Khanna et al., 2010, BMC Genomics 11(1): Towards a membrane proteome in Drosophila: a method for the isolation of plasma membrane. [FBrf0210978] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Bellen, 2011.5.24, set932.xml set932.xml [FBrf0213718] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Kodira, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126678]