FlyBase Gene Report: Dmel\Cad96Cb

General Information

Symbol

Dmel\Cad96Cb

Species

D. melanogaster

Name

Cadherin 96Cb

Annotation Symbol

CG13664

Feature Type

protein_coding_gene

FlyBase ID

FBgn0039294

Gene Model Status

Current

Stock Availability

7 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

Cad96C

Key Links

Genomic Location

Cytogenetic map

96C7-96C7

Sequence location

3R:25,224,156..25,232,321 [-]

Recombination map

3-87

RefSeq locus

NT_033777 REGION:25224156..25232321

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (7 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables calcium ion binding

inferred from sequence model

(Hill et al., 2001)

inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919

(InterPro Project Members, 2004-)

Biological Process (5 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in open tracheal system development

inferred from genetic interaction with FLYBASE:shg; FB:FBgn0003391

(Lovegrove et al., 2006)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

inferred from sequence or structural similarity

(Hynes and Zhao, 2000)

involved_in cell adhesion

inferred from biological aspect of ancestor with PANTHER:PTN001932250

(GO Reference Genome Project, 2011-)

involved_in cell-cell adhesion mediated by cadherin

inferred from sequence model

(Hill et al., 2001)

involved_in homophilic cell adhesion via plasma membrane adhesion molecules

inferred from electronic annotation with InterPro:IPR002126

(InterPro Project Members, 2004-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN001932250

(GO Reference Genome Project, 2011-)

located_in plasma membrane

inferred from sequence or structural similarity

(Hynes and Zhao, 2000)

inferred from electronic annotation with InterPro:IPR020894

(InterPro Project Members, 2004-)

Gene Group (FlyBase)

CADHERINS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

CADHERINS -: The cadherin superfamily represent a diverse group of transmembrane receptors which mediate cell-cell adhesion. Cadherins are defined by the presence of cadherin domains, typically organised in tandem repeats, which mediate calcium-dependent homophilic interactions between cadherin molecules. (Adapted from FBrf0146675).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Cad96Cb for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry A0A0B4LHM7)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.49

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Cad96Cb-RB

FBtr0301090

NM_143098

3016

786

Cad96Cb-RC

FBtr0302299

NM_001170256

2991

785

Cad96Cb-RD

FBtr0339260

NM_001300595

3003

789

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Cad96Cb-PB

FBpp0290312

85.5

786

6.01

FBpp0291505

85.3

785

6.01

FBpp0308367

85.8

789

6.01

A0A0B4LHM7

NP_001287524

AHN57523

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cad96Cb using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Cad96Cb_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.37

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 14 -- 15

spiracular chamber | restricted

(Lovegrove et al., 2006)

Additional Descriptive Data

Several cadherin genes are expressed in an overlapping pattern in the developing posterior spiracles. Cad96Cb and Cad88C transcripts are expressed in a group of deeper spiracle cells. Cad74A is expressed in a group of less elongated spiracle cells located above the Cad88C/Cad96Cb-expressing cells, and Cad86C is expressed in a row of stigmatophore cells surrounding the spiracular chamber.

(Lovegrove et al., 2006)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Cad96Cb in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Cad96Cb

View exonic expression by tissue for Dmel\Cad96Cb

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0039294

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

43033/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0039294

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0039294

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0039294

Flygut - An atlas of the Drosophila adult midgut

FBgn0039294

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 2 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 7 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Cad96Cb

Transgenic constructs containing regulatory region of Cad96Cb

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(3R)FDD-0089346

(DrosDel Project, 2008.11.14)

Inferred from location ( 6 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

partially lethal - majority die, with Scer\GAL4^pnr-MD237

Cad96Cb^GD8088

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

viable, with Scer\GAL4^Mef2.PR

viable, with Scer\GAL4^pnr-MD237

Other Phenotypes

Allele

some die during pupal stage, with Scer\GAL4^pnr-MD237

Cad96Cb^GD8088

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (73)

Hsap\PCDHB1

2 of 14

Yes

Hsap\PCDHB7

2 of 14

Yes

Hsap\PCDHB11

2 of 14

Yes

Hsap\PCDHB12

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\PCDH7

1 of 14

Yes

Hsap\PCDH8

1 of 14

Yes

Hsap\PCDH9

1 of 14

Yes

Hsap\PCDH10

1 of 14

Hsap\PCDH12

1 of 14

Yes

Hsap\PCDH17

1 of 14

Yes

Hsap\PCDH18

1 of 14

Yes

Hsap\PCDH19

1 of 14

Yes

Hsap\PCDH20

1 of 14

Yes

Hsap\PCDHA1

1 of 14

Yes

Hsap\PCDHA2

1 of 14

Yes

Hsap\PCDHA3

1 of 14

Hsap\PCDHA4

1 of 14

Yes

Hsap\PCDHA5

1 of 14

Yes

Hsap\PCDHA6

1 of 14

Yes

Hsap\PCDHA7

1 of 14

Yes

Hsap\PCDHA8

1 of 14

Yes

Hsap\PCDHA9

1 of 14

Yes

Hsap\PCDHA10

1 of 14

Yes

Hsap\PCDHA11

1 of 14

Yes

Hsap\PCDHA12

1 of 14

Yes

Hsap\PCDHA13

1 of 14

Yes

Hsap\PCDHAC1

1 of 14

Yes

Hsap\PCDHAC2

1 of 14

Hsap\PCDHB2

1 of 14

Yes

Hsap\PCDHB3

1 of 14

Yes

Hsap\PCDHB4

1 of 14

Yes

Hsap\PCDHB5

1 of 14

Yes

Hsap\PCDHB6

1 of 14

Yes

Hsap\PCDHB8

1 of 14

Yes

Hsap\PCDHB9

1 of 14

Yes

Hsap\PCDHB10

1 of 14

Yes

Hsap\PCDHB13

1 of 14

Yes

Hsap\PCDHB14

1 of 14

Yes

Hsap\PCDHB15

1 of 14

Yes

Hsap\PCDHB16

1 of 14

Yes

Hsap\PCDHB18P

1 of 14

Yes

Hsap\PCDHGA1

1 of 14

Yes

Hsap\PCDHGA2

1 of 14

Yes

Hsap\PCDHGA3

1 of 14

Hsap\PCDHGA4

1 of 14

Yes

Hsap\PCDHGA5

1 of 14

Yes

Hsap\PCDHGA6

1 of 14

Yes

Hsap\PCDHGA7

1 of 14

Yes

Hsap\PCDHGA8

1 of 14

Yes

Hsap\PCDHGA9

1 of 14

Yes

Hsap\PCDHGA10

1 of 14

Yes

Hsap\PCDHGA11

1 of 14

Yes

Hsap\PCDHGA12

1 of 14

Yes

Hsap\PCDHGB1

1 of 14

Yes

Hsap\PCDHGB2

1 of 14

Yes

Hsap\PCDHGB3

1 of 14

Yes

Hsap\PCDHGB4

1 of 14

Yes

Hsap\PCDHGB5

1 of 14

Yes

Hsap\PCDHGB6

1 of 14

Yes

Hsap\PCDHGB7

1 of 14

Yes

Hsap\PCDHGC3

1 of 14

Yes

Hsap\PCDHGC4

1 of 14

Hsap\PCDHGC5

1 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (52)

Rnor\Cdhr1

1 of 14

Yes

Rnor\Cdhr2

1 of 14

Yes

Rnor\Cdhr3

1 of 14

Yes

Rnor\Celsr3

1 of 14

Yes

Rnor\Dchs2

1 of 14

Yes

Rnor\LOC108348201

1 of 14

Yes

Rnor\Pcdh1

1 of 14

Yes

Rnor\Pcdh7

1 of 14

Yes

Rnor\Pcdh8

1 of 14

Yes

Rnor\Pcdh9

1 of 14

Yes

Rnor\Pcdh10

1 of 14

Yes

Rnor\Pcdh12

1 of 14

Yes

Rnor\Pcdh17

1 of 14

Yes

Rnor\Pcdh18

1 of 14

Yes

Rnor\Pcdh19

1 of 14

Yes

Rnor\Pcdh20

1 of 14

Yes

Rnor\Pcdha4

1 of 14

Yes

Rnor\Pcdhb1

1 of 14

Yes

Rnor\Pcdhb2

1 of 14

Yes

Rnor\Pcdhb3

1 of 14

Yes

Rnor\Pcdhb4

1 of 14

Yes

Rnor\Pcdhb5

1 of 14

Yes

Rnor\Pcdhb6l

1 of 14

Yes

Rnor\Pcdhb7

1 of 14

Yes

Rnor\Pcdhb8

1 of 14

Yes

Rnor\Pcdhb9

1 of 14

Yes

Rnor\Pcdhb10

1 of 14

Yes

Rnor\Pcdhb11

1 of 14

Yes

Rnor\Pcdhb12

1 of 14

Yes

Rnor\Pcdhb14

1 of 14

Yes

Rnor\Pcdhb16l

1 of 14

Yes

Rnor\Pcdhb19

1 of 14

Yes

Rnor\Pcdhb20

1 of 14

Yes

Rnor\Pcdhb21

1 of 14

Yes

Rnor\Pcdhb22

1 of 14

Yes

Rnor\Pcdhga1

1 of 14

Yes

Rnor\Pcdhga2

1 of 14

Yes

Rnor\Pcdhga3

1 of 14

Yes

Rnor\Pcdhga4

1 of 14

Yes

Rnor\Pcdhga5

1 of 14

Yes

Rnor\Pcdhga7

1 of 14

Yes

Rnor\Pcdhga8

1 of 14

Yes

Rnor\Pcdhga9

1 of 14

Yes

Rnor\Pcdhga10

1 of 14

Yes

Rnor\Pcdhga11

1 of 14

Yes

Rnor\Pcdhgb1

1 of 14

Yes

Rnor\Pcdhgb4

1 of 14

Yes

Rnor\Pcdhgb5

1 of 14

Yes

Rnor\Pcdhgb6

1 of 14

Yes

Rnor\Pcdhgb7

1 of 14

Yes

Rnor\Pcdhgb8

1 of 14

Yes

Rnor\Pcdhgc3

1 of 14

Yes

Mus musculus (laboratory mouse) (74)

Mmus\Pcdhb15

2 of 14

Yes

Mmus\Cdhr1

1 of 14

Mmus\Cdhr2

1 of 14

Mmus\Cdhr3

1 of 14

Yes

Mmus\Cdhr4

1 of 14

Yes

Mmus\Celsr2

1 of 14

Mmus\Celsr3

1 of 14

Mmus\Gm37013

1 of 14

Yes

Mmus\Pcdh1

1 of 14

Mmus\Pcdh7

1 of 14

Mmus\Pcdh8

1 of 14

Yes

Mmus\Pcdh9

1 of 14

Mmus\Pcdh10

1 of 14

Yes

Mmus\Pcdh12

1 of 14

Yes

Mmus\Pcdh17

1 of 14

Yes

Mmus\Pcdh18

1 of 14

Yes

Mmus\Pcdh19

1 of 14

Yes

Mmus\Pcdh20

1 of 14

Yes

Mmus\Pcdha1

1 of 14

Yes

Mmus\Pcdha2

1 of 14

Yes

Mmus\Pcdha3

1 of 14

Yes

Mmus\Pcdha4

1 of 14

Yes

Mmus\Pcdha5

1 of 14

Yes

Mmus\Pcdha6

1 of 14

Yes

Mmus\Pcdha7

1 of 14

Yes

Mmus\Pcdha8

1 of 14

Yes

Mmus\Pcdha9

1 of 14

Yes

Mmus\Pcdha10

1 of 14

Yes

Mmus\Pcdha11

1 of 14

Yes

Mmus\Pcdha12

1 of 14

Yes

Mmus\Pcdhac1

1 of 14

Yes

Mmus\Pcdhac2

1 of 14

Yes

Mmus\Pcdhb1

1 of 14

Yes

Mmus\Pcdhb2

1 of 14

Yes

Mmus\Pcdhb3

1 of 14

Yes

Mmus\Pcdhb4

1 of 14

Yes

Mmus\Pcdhb5

1 of 14

Yes

Mmus\Pcdhb6

1 of 14

Yes

Mmus\Pcdhb7

1 of 14

Yes

Mmus\Pcdhb8

1 of 14

Yes

Mmus\Pcdhb9

1 of 14

Yes

Mmus\Pcdhb10

1 of 14

Yes

Mmus\Pcdhb11

1 of 14

Yes

Mmus\Pcdhb12

1 of 14

Yes

Mmus\Pcdhb13

1 of 14

Yes

Mmus\Pcdhb14

1 of 14

Yes

Mmus\Pcdhb16

1 of 14

Yes

Mmus\Pcdhb17

1 of 14

Mmus\Pcdhb18

1 of 14

Yes

Mmus\Pcdhb19

1 of 14

Yes

Mmus\Pcdhb20

1 of 14

Yes

Mmus\Pcdhb21

1 of 14

Yes

Mmus\Pcdhb22

1 of 14

Yes

Mmus\Pcdhga1

1 of 14

Yes

Mmus\Pcdhga2

1 of 14

Mmus\Pcdhga3

1 of 14

Yes

Mmus\Pcdhga4

1 of 14

Yes

Mmus\Pcdhga5

1 of 14

Yes

Mmus\Pcdhga6

1 of 14

Yes

Mmus\Pcdhga7

1 of 14

Yes

Mmus\Pcdhga8

1 of 14

Yes

Mmus\Pcdhga9

1 of 14

Yes

Mmus\Pcdhga10

1 of 14

Yes

Mmus\Pcdhga11

1 of 14

Yes

Mmus\Pcdhga12

1 of 14

Yes

Mmus\Pcdhgb1

1 of 14

Yes

Mmus\Pcdhgb2

1 of 14

Yes

Mmus\Pcdhgb4

1 of 14

Yes

Mmus\Pcdhgb5

1 of 14

Mmus\Pcdhgb6

1 of 14

Yes

Mmus\Pcdhgb7

1 of 14

Yes

Mmus\Pcdhgc3

1 of 14

Yes

Mmus\Pcdhgc4

1 of 14

Yes

Mmus\Pcdhgc5

1 of 14

Yes

Xenopus tropicalis (Western clawed frog) (35)

Xtro\avpr1b

1 of 13

Yes

Xtro\celsr3

1 of 13

Yes

Xtro\cenpv

1 of 13

Yes

Xtro\dcaf17

1 of 13

Yes

Xtro\fat3

1 of 13

Yes

Xtro\fat4

1 of 13

Yes

Xtro\LOC100485160

1 of 13

Yes

Xtro\LOC100489479

1 of 13

Yes

Xtro\LOC100493106

1 of 13

Yes

Xtro\LOC101733947

1 of 13

Yes

Xtro\LOC105946889

1 of 13

Yes

Xtro\LOC105946895

1 of 13

Yes

Xtro\ndufa9

1 of 13

Yes

Xtro\pcdh1

1 of 13

Yes

Xtro\pcdh7

1 of 13

Yes

Xtro\pcdh8.2

1 of 13

Yes

Xtro\pcdh8l

1 of 13

Yes

Xtro\pcdh8

1 of 13

Yes

Xtro\pcdh9

1 of 13

Yes

Xtro\pcdh10

1 of 13

Yes

Xtro\pcdh11x

1 of 13

Yes

Xtro\pcdh17

1 of 13

Yes

Xtro\pcdh18

1 of 13

Yes

Xtro\pcdh19

1 of 13

Yes

Xtro\pcdh20

1 of 13

Yes

Xtro\pcdha6

1 of 13

Yes

Xtro\pcdha8

1 of 13

Yes

Xtro\pcdha13

1 of 13

Yes

Xtro\pcdhac2

1 of 13

Yes

Xtro\pcdhga11

1 of 13

Yes

Xtro\pcdhgb5

1 of 13

Yes

Xtro\pcdhgc4

1 of 13

Yes

Xtro\prodh

1 of 13

Yes

Xtro\rptor

1 of 13

Yes

Xtro\snrpf

1 of 13

Yes

Danio rerio (Zebrafish) (67)

Drer\cdhr1a

1 of 14

Yes

Drer\dchs1b

1 of 14

Yes

Drer\fat2

1 of 14

Yes

Drer\LOC100006777

1 of 14

Yes

Drer\LOC100006797

1 of 14

Yes

Drer\LOC103908739

1 of 14

Yes

Drer\LOC103911742

1 of 14

Yes

Drer\LOC108191529

1 of 14

Yes

Drer\LOC110440084

1 of 14

Yes

Drer\pcdh1a3

1 of 14

Yes

Drer\pcdh1a4

1 of 14

Yes

Drer\pcdh1a

1 of 14

Yes

Drer\pcdh1b

1 of 14

Yes

Drer\pcdh1g1

1 of 14

Yes

Drer\pcdh1g2

1 of 14

Yes

Drer\pcdh1g3

1 of 14

Yes

Drer\pcdh1g9

1 of 14

Yes

Drer\pcdh1g11

1 of 14

Yes

Drer\pcdh1g13

1 of 14

Yes

Drer\pcdh1g14

1 of 14

Yes

Drer\pcdh1g18

1 of 14

Yes

Drer\pcdh1g22

1 of 14

Yes

Drer\pcdh1g26

1 of 14

Yes

Drer\pcdh1g29

1 of 14

Yes

Drer\pcdh1g30

1 of 14

Yes

Drer\pcdh1g31

1 of 14

Yes

Drer\pcdh1g32

1 of 14

Yes

Drer\pcdh1g33

1 of 14

Yes

Drer\pcdh1gb2

1 of 14

Yes

Drer\pcdh1gb9

1 of 14

Yes

Drer\pcdh1gc5

1 of 14

Yes

Drer\pcdh1gc6

1 of 14

Yes

Drer\pcdh2aa1

1 of 14

Yes

Drer\pcdh2aa15

1 of 14

Yes

Drer\pcdh2ab1

1 of 14

Yes

Drer\pcdh2ab2

1 of 14

Yes

Drer\pcdh2ab3

1 of 14

Yes

Drer\pcdh2ab5

1 of 14

Yes

Drer\pcdh2ab6

1 of 14

Yes

Drer\pcdh2ab7

1 of 14

Yes

Drer\pcdh2ab9

1 of 14

Yes

Drer\pcdh2ab10

1 of 14

Yes

Drer\pcdh2ab11

1 of 14

Yes

Drer\pcdh2ab12

1 of 14

Yes

Drer\pcdh2ac

1 of 14

Yes

Drer\pcdh2g10

1 of 14

Yes

Drer\pcdh2g17

1 of 14

Yes

Drer\pcdh7a

1 of 14

Yes

Drer\pcdh7b

1 of 14

Yes

Drer\pcdh8

1 of 14

Yes

Drer\pcdh9

1 of 14

Yes

Drer\pcdh10a

1 of 14

Yes

Drer\pcdh10b

1 of 14

Yes

Drer\pcdh11

1 of 14

Yes

Drer\pcdh12

1 of 14

Yes

Drer\pcdh17

1 of 14

Yes

Drer\pcdh18a

1 of 14

Yes

Drer\pcdh18b

1 of 14

Yes

Drer\pcdh19

1 of 14

Yes

Drer\pcdh20

1 of 14

Yes

Drer\pcdh20

1 of 14

Yes

Drer\pcdhb

1 of 14

Yes

Drer\si:ch73-233f7.1

1 of 14

Yes

Drer\si:ch73-233f7.3

1 of 14

Yes

Drer\si:ch73-233f7.6

1 of 14

Yes

Drer\si:ch73-379j16.2

1 of 14

Yes

Drer\si:ch211-199f5.1

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (2)

Cele\cdh-9

8 of 14

Yes

Cele\fmi-1

1 of 14

Anopheles gambiae (African malaria mosquito) (2)

Agam\AgaP_AGAP003607

11 of 12

Yes

Agam\AgaP_AGAP002310

1 of 12

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Cad96Cb. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (8)

1 of 13

1 of 13

1 of 13

1 of 13

kug

1 of 13

stan

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Other Interaction Browsers

Summary of Genetic Interactions

esyN Network Diagram

Other Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0039294

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-87

Cytogenetic map

96C7-96C7

Sequence location

3R:25,224,156..25,232,321 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

96C7-96C7

Limits computationally determined from genome sequence between P{lacW}OstStt3^j2D9 and P{PZ}Aats-gln⁰⁵⁴⁶¹

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-87

(FlyBase, 2016)

3-85.8

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (7)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

25860

y¹ v¹; P{TRiP.JF01881}attP2

86012

w¹¹¹⁸; PBac{RB}Cad96Cb^e01506

54029

y¹ v¹; P{TRiP.HMJ21472}attP40

97613

y¹ w^*; TI{CRIMIC.TG4.1}Cad96Cb^{CR02788-TG4.1}/TM3, Sb¹ Ser¹

NIG-Fly

HMJ21472

y¹ v¹; P{TRiP.HMJ21472}attP40/CyO

VDRC

v103296

P{KK112803}VIE-260B

v39800

w¹¹¹⁸; P{GD8088}v39800

Genomic Clones (14)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (7)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

IP03406

Other clones

IP03306

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0039294

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0039294

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Source for merge of: CG13664 Cad96Cb

(FlyBase Genome Annotators, 2006)

Additional comments

Annotations CG10421 and CG13664 merged as CG10421 (which corresponds to Cad96Cb) in release 5.1 of the genome annotation.

(FlyBase Genome Annotators, 2006)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (10)

Reported As

Symbol Synonym

CG10421

(Lovegrove et al., 2006, Hill et al., 2001)

CG13664

(Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Perkins et al., 2009.1.15)

CT29262

(Hynes and Zhao, 2000)

Cad96C

(Faisal et al., 2014, Lovegrove et al., 2006)

Cad96Cb

(Li et al., 2022, DeAngelis et al., 2021, Gene Disruption Project members, 2018-, Zartman et al., 2009, Fung et al., 2008)

DCad96Cb

(Tepass et al., 2000)

cad96C

(Maurel-Zaffran et al., 2010)

cad96Cb

(Lovegrove et al., 2006)

cg13664

(Jensen et al., 2008)

Name Synonyms

Cad96Cb

(Fung et al., 2008)

Cadherin 96Cb

Secondary FlyBase IDs

FBan0010421
FBgn0039295

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 35 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

43033

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AI945808

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

A0A0B4LHM7

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

A0A0B4LHM7

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0039294

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

43033/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0039294

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0039294

FlyMine - An integrated database for Drosophila genomics

FBgn0039294

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG13664

MARRVEL_MODEL - MARRVEL (model organism gene)

43033

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0039294

DroID - A comprehensive database of gene and protein interactions.

FBgn0039294

DRSC - Results frm RNAi screens

FBgn0039294

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Cad96Cb_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0039294

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0039294

Flygut - An atlas of the Drosophila adult midgut

FBgn0039294

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC031143

References (36)

The following external sites may use different assemblies or annotations than FlyBase.

-0.37

Report Sections