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Gene Dmel\CG11875

General Information
Symbol	Dmel\CG11875	Species	D. melanogaster
Name		Annotation symbol	CG11875
Feature type	protein_coding_gene	FlyBase ID	FBgn0039301
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	96C8-96C8	Sequence location	3R:21,073,600..21,074,822 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG11875 (FBgn0039301). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: WD40 repeat; WD40 repeat 2; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1627803_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11875. Gene sequence location is 3R:21073600..21074822.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN28643 HFA14419
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 96C8-96C8   Limits computationally determined from genome sequence between P{lacW}OstStt3j2D9 and P{PZ}Aats-gln05461
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG11875 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG11875-RA FBtr0084812  NM_143103   1100   320
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG11875-PA   FBpp0084187   35.4   320   6.30     NP_651360   AAF56429
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • WD40 repeat (IPR001680) WD40 repeat-like-containing domain (IPR011046) WD40-repeat-containing domain (IPR017986) WD40/YVTN repeat-like-containing domain (IPR015943) WD40 repeat, subgroup (IPR019781) WD40 repeat 2 (IPR019782)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF56429   AI533994   BF498173   BI637153   BI640129   BT012297   CO153495   CO282787   CO321707   EC200336   EC210956   EC233959   EC259094   EV583276   EV600375   GH942849   GH944215   GH945587   GH946412   GH946612   GH948538   GH953353   GH955453   GH955845   GH956611   GH957012   GH957760   GH958087   GH958092   GH960142   GH963126   GH965255   GH965749   GH970575   GH973011   GH975163   GH975692   GH976270   GH978738   GH979424   GH979561   GH980514   GH980536   GH980859   GH983351
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VBU8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039301    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039301 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039301 expression level Developmental Stage   Expression Level embryo 00-02hr    4315 embryo 02-04hr    1969 embryo 04-06hr    2983 embryo 06-08hr    2504 embryo 08-10hr    1627 embryo 10-12hr    1275 embryo 12-14hr    537 embryo 14-16hr    730 embryo 16-18hr    591 embryo 18-20hr    446 embryo 20-22hr    287 embryo 22-24hr    233 larva L1    1128 larva L2    1069 larva L3 12hr old    754 larva L3 puffstage 1-2    747 larva L3 puffstage 3-6    884 larva L3 puffstage 7-9    1030 white prepupae new    899 white prepupae 12hr    976 white prepupae 24hr    1078 pupae 2d postWPP    559 pupae 3d postWPP    334 pupae 4d postWPP    561 adult male 01day    394 adult male 05day    470 adult male 30day    552 adult female 01day    2002 adult female 05day    2640 adult female 30day    3092 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4315) embryo 02-04hr  (1969) embryo 04-06hr  (2983) embryo 06-08hr  (2504) embryo 08-10hr  (1627) embryo 10-12hr  (1275) embryo 12-14hr  (537) embryo 14-16hr  (730) embryo 16-18hr  (591) embryo 18-20hr  (446) embryo 20-22hr  (287) embryo 22-24hr  (233) larva L1  (1128) larva L2  (1069) larva L3 12hr old  (754) larva L3 puffstage 1-2  (747) larva L3 puffstage 3-6  (884) larva L3 puffstage 7-9  (1030) white prepupae new  (899) white prepupae 12hr  (976) white prepupae 24hr  (1078) pupae 2d postWPP  (559) pupae 3d postWPP  (334) pupae 4d postWPP  (561) adult male 01day  (394) adult male 05day  (470) adult male 30day  (552) adult female 01day  (2002) adult female 05day  (2640) adult female 30day  (3092) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4315) embryo 02-04hr  (1969) embryo 04-06hr  (2983) embryo 06-08hr  (2504) embryo 08-10hr  (1627) embryo 10-12hr    1275 embryo 12-14hr    537 embryo 14-16hr    730 embryo 16-18hr    591 embryo 18-20hr    446 embryo 20-22hr    287 embryo 22-24hr    233 larva L1    1128 larva L2    1069 larva L3 12hr old    754 larva L3 puffstage 1-2    747 larva L3 puffstage 3-6    884 larva L3 puffstage 7-9    1030 white prepupae new    899 white prepupae 12hr    976 white prepupae 24hr    1078 pupae 2d postWPP    559 pupae 3d postWPP    334 pupae 4d postWPP    561 adult male 01day    394 adult male 05day    470 adult male 30day    552 adult female 01day  (2002) adult female 05day  (2640) adult female 30day  (3092) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4315 embryo 02-04hr    1969 embryo 04-06hr    2983 embryo 06-08hr    2504 embryo 08-10hr    1627 embryo 10-12hr    1275 embryo 12-14hr    537 embryo 14-16hr    730 embryo 16-18hr    591 embryo 18-20hr    446 embryo 20-22hr    287 embryo 22-24hr    233 larva L1    1128 larva L2    1069 larva L3 12hr old    754 larva L3 puffstage 1-2    747 larva L3 puffstage 3-6    884 larva L3 puffstage 7-9    1030 white prepupae new    899 white prepupae 12hr    976 white prepupae 24hr    1078 pupae 2d postWPP    559 pupae 3d postWPP    334 pupae 4d postWPP    561 adult male 01day    394 adult male 05day    470 adult male 30day    552 adult female 01day    2002 adult female 05day    2640 adult female 30day    3092 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4315 embryo 02-04hr    1969 embryo 04-06hr    2983 embryo 06-08hr    2504 embryo 08-10hr    1627 embryo 10-12hr    1275 embryo 12-14hr    537 embryo 14-16hr    730 embryo 16-18hr    591 embryo 18-20hr    446 embryo 20-22hr    287 embryo 22-24hr    233 larva L1    1128 larva L2    1069 larva L3 12hr old    754 larva L3 puffstage 1-2    747 larva L3 puffstage 3-6    884 larva L3 puffstage 7-9    1030 white prepupae new    899 white prepupae 12hr    976 white prepupae 24hr    1078 pupae 2d postWPP    559 pupae 3d postWPP    334 pupae 4d postWPP    561 adult male 01day    394 adult male 05day    470 adult male 30day    552 adult female 01day    2002 adult female 05day    2640 adult female 30day    3092 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039301 expression level Developmental Stage   Expression Level embryo 00-02hr    4315 embryo 02-04hr    1969 embryo 04-06hr    2983 embryo 06-08hr    2504 embryo 08-10hr    1627 embryo 10-12hr    1275 embryo 12-14hr    537 embryo 14-16hr    730 embryo 16-18hr    591 embryo 18-20hr    446 embryo 20-22hr    287 embryo 22-24hr    233 larva L1    1128 larva L2    1069 larva L3 12hr old    754 larva L3 puffstage 1-2    747 larva L3 puffstage 3-6    884 larva L3 puffstage 7-9    1030 white prepupae new    899 white prepupae 12hr    976 white prepupae 24hr    1078 pupae 2d postWPP    559 pupae 3d postWPP    334 pupae 4d postWPP    561 adult male 01day    394 adult male 05day    470 adult male 30day    552 adult female 01day    2002 adult female 05day    2640 adult female 30day    3092 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4315) embryo 02-04hr  (1969) embryo 04-06hr  (2983) embryo 06-08hr  (2504) embryo 08-10hr  (1627) embryo 10-12hr  (1275) embryo 12-14hr  (537) embryo 14-16hr  (730) embryo 16-18hr  (591) embryo 18-20hr  (446) embryo 20-22hr  (287) embryo 22-24hr  (233) larva L1  (1128) larva L2  (1069) larva L3 12hr old  (754) larva L3 puffstage 1-2  (747) larva L3 puffstage 3-6  (884) larva L3 puffstage 7-9  (1030) white prepupae new  (899) white prepupae 12hr  (976) white prepupae 24hr  (1078) pupae 2d postWPP  (559) pupae 3d postWPP  (334) pupae 4d postWPP  (561) adult male 01day  (394) adult male 05day  (470) adult male 30day  (552) adult female 01day  (2002) adult female 05day  (2640) adult female 30day  (3092) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4315) embryo 02-04hr  1969 embryo 04-06hr  (2983) embryo 06-08hr  (2504) embryo 08-10hr  1627 embryo 10-12hr    1275 embryo 12-14hr    537 embryo 14-16hr    730 embryo 16-18hr    591 embryo 18-20hr    446 embryo 20-22hr    287 embryo 22-24hr    233 larva L1    1128 larva L2    1069 larva L3 12hr old    754 larva L3 puffstage 1-2    747 larva L3 puffstage 3-6    884 larva L3 puffstage 7-9    1030 white prepupae new    899 white prepupae 12hr    976 white prepupae 24hr    1078 pupae 2d postWPP    559 pupae 3d postWPP    334 pupae 4d postWPP    561 adult male 01day    394 adult male 05day    470 adult male 30day    552 adult female 01day  2002 adult female 05day  (2640) adult female 30day  (3092) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4315 embryo 02-04hr    1969 embryo 04-06hr    2983 embryo 06-08hr    2504 embryo 08-10hr    1627 embryo 10-12hr    1275 embryo 12-14hr    537 embryo 14-16hr    730 embryo 16-18hr    591 embryo 18-20hr    446 embryo 20-22hr    287 embryo 22-24hr    233 larva L1    1128 larva L2    1069 larva L3 12hr old    754 larva L3 puffstage 1-2    747 larva L3 puffstage 3-6    884 larva L3 puffstage 7-9    1030 white prepupae new    899 white prepupae 12hr    976 white prepupae 24hr    1078 pupae 2d postWPP    559 pupae 3d postWPP    334 pupae 4d postWPP    561 adult male 01day    394 adult male 05day    470 adult male 30day    552 adult female 01day    2002 adult female 05day    2640 adult female 30day    3092 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4315 embryo 02-04hr    1969 embryo 04-06hr    2983 embryo 06-08hr    2504 embryo 08-10hr    1627 embryo 10-12hr    1275 embryo 12-14hr    537 embryo 14-16hr    730 embryo 16-18hr    591 embryo 18-20hr    446 embryo 20-22hr    287 embryo 22-24hr    233 larva L1    1128 larva L2    1069 larva L3 12hr old    754 larva L3 puffstage 1-2    747 larva L3 puffstage 3-6    884 larva L3 puffstage 7-9    1030 white prepupae new    899 white prepupae 12hr    976 white prepupae 24hr    1078 pupae 2d postWPP    559 pupae 3d postWPP    334 pupae 4d postWPP    561 adult male 01day    394 adult male 05day    470 adult male 30day    552 adult female 01day    2002 adult female 05day    2640 adult female 30day    3092 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0039301    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0039301 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0039301 expression level Tissue   Expression Level Larval Central Nervous System    184.925 Larval Midgut    40.4 Larval Hindgut    52.9 Larval Malpighian Tubules    33.8 Larval Fat Body no informative data Larval Salivary Gland    122.8 Larval Trachea    133.35 Larval Carcass    60.7 Adult Head    34 Adult Eye    35.5 Adult Brain    37.2 Adult Thoracic-Abdominal Ganglion    27.4 Adult Crop    39.8 Adult Midgut    42.1 Adult Hindgut no informative data Adult Malpighian Tubules    50 Adult Fat Body    41.5 Adult Salivary Gland no informative data Adult Heart    29.125 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    237.4 Adult Testis    38.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    184.925 Larval Midgut    40.4 Larval Hindgut    52.9 Larval Malpighian Tubules    33.8 Larval Fat Body no informative data Larval Salivary Gland    122.8 Larval Trachea    133.35 Larval Carcass    60.7 Adult Head    34 Adult Eye    35.5 Adult Brain    37.2 Adult Thoracic-Abdominal Ganglion    27.4 Adult Crop    39.8 Adult Midgut    42.1 Adult Hindgut no informative data Adult Malpighian Tubules    50 Adult Fat Body    41.5 Adult Salivary Gland no informative data Adult Heart    29.125 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    237.4 Adult Testis    38.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    184.925 Larval Midgut    40.4 Larval Hindgut    52.9 Larval Malpighian Tubules    33.8 Larval Fat Body no informative data Larval Salivary Gland    122.8 Larval Trachea    133.35 Larval Carcass    60.7 Adult Head    34 Adult Eye    35.5 Adult Brain    37.2 Adult Thoracic-Abdominal Ganglion    27.4 Adult Crop    39.8 Adult Midgut    42.1 Adult Hindgut no informative data Adult Malpighian Tubules    50 Adult Fat Body    41.5 Adult Salivary Gland no informative data Adult Heart    29.125 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    237.4 Adult Testis    38.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    184.925 Larval Midgut    40.4 Larval Hindgut    52.9 Larval Malpighian Tubules    33.8 Larval Fat Body no informative data Larval Salivary Gland    122.8 Larval Trachea    133.35 Larval Carcass    60.7 Adult Head    34 Adult Eye    35.5 Adult Brain    37.2 Adult Thoracic-Abdominal Ganglion    27.4 Adult Crop    39.8 Adult Midgut    42.1 Adult Hindgut no informative data Adult Malpighian Tubules    50 Adult Fat Body    41.5 Adult Salivary Gland no informative data Adult Heart    29.125 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    237.4 Adult Testis    38.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0039301 expression level Tissue   Expression Level Larval Central Nervous System    184.925 Larval Midgut    40.4 Larval Hindgut    52.9 Larval Malpighian Tubules    33.8 Larval Fat Body no informative data Larval Salivary Gland    122.8 Larval Trachea    133.35 Larval Carcass    60.7 Adult Head    34 Adult Eye    35.5 Adult Brain    37.2 Adult Thoracic-Abdominal Ganglion    27.4 Adult Crop    39.8 Adult Midgut    42.1 Adult Hindgut no informative data Adult Malpighian Tubules    50 Adult Fat Body    41.5 Adult Salivary Gland no informative data Adult Heart    29.125 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    237.4 Adult Testis    38.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    184.925 Larval Midgut    40.4 Larval Hindgut    52.9 Larval Malpighian Tubules    33.8 Larval Fat Body no informative data Larval Salivary Gland    122.8 Larval Trachea    133.35 Larval Carcass    60.7 Adult Head    34 Adult Eye    35.5 Adult Brain    37.2 Adult Thoracic-Abdominal Ganglion    27.4 Adult Crop    39.8 Adult Midgut    42.1 Adult Hindgut no informative data Adult Malpighian Tubules    50 Adult Fat Body    41.5 Adult Salivary Gland no informative data Adult Heart    29.125 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    237.4 Adult Testis    38.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    184.925 Larval Midgut    40.4 Larval Hindgut    52.9 Larval Malpighian Tubules    33.8 Larval Fat Body no informative data Larval Salivary Gland    122.8 Larval Trachea    133.35 Larval Carcass    60.7 Adult Head    34 Adult Eye    35.5 Adult Brain    37.2 Adult Thoracic-Abdominal Ganglion    27.4 Adult Crop    39.8 Adult Midgut    42.1 Adult Hindgut no informative data Adult Malpighian Tubules    50 Adult Fat Body    41.5 Adult Salivary Gland no informative data Adult Heart    29.125 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    237.4 Adult Testis    38.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    184.925 Larval Midgut    40.4 Larval Hindgut    52.9 Larval Malpighian Tubules    33.8 Larval Fat Body no informative data Larval Salivary Gland    122.8 Larval Trachea    133.35 Larval Carcass    60.7 Adult Head    34 Adult Eye    35.5 Adult Brain    37.2 Adult Thoracic-Abdominal Ganglion    27.4 Adult Crop    39.8 Adult Midgut    42.1 Adult Hindgut no informative data Adult Malpighian Tubules    50 Adult Fat Body    41.5 Adult Salivary Gland no informative data Adult Heart    29.125 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    237.4 Adult Testis    38.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body no informative data Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut no informative data Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    34   NA  Eye    35.5   NA  Brain    37.2   184.925  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    27.4   NA  Crop    39.8   40.4  Midgut    42.1   52.9  Hindgut    no informative data   33.8  Malpighian Tubules    50   no informative data  Fat Body    41.5   122.8  Salivary Gland    no informative data   NA  Heart    29.125   133.35  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    237.4   NA  Testis    38.2   NA  Male Accessory Gland    no informative data   60.7  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_13
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039301 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11875-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG11875GD7413 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG11875 Class Mutagen Stocks Known lesion CG11875MB05519 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG11875 Class Mutagen Stocks Known lesion CG11875GD7413 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG11875KK108643 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)FDD-0089346 (DrosDel Project, 2008.11.14) Df(3R)FDD-0247625 (DrosDel Project, 2008.11.14) Df(3R)FDD-0247627 (DrosDel Project, 2008.11.14)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7413} NA P{KK108643} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system Mi{ET1}CG11875MB05519 No
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG11875 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039301 DroID - A comprehensive database of gene and protein interactions. • FBgn0039301 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43040
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17555 Dere\GG11381 Dgri\GH17354 Dmoj\GI23891 Dper\GL11990 Dpse\GA11251 Dsec\GM17824 Dsim\GD21192 Dvir\GJ23983 Dwil\GK12951 Dyak\GE23578
Curated drosophilid orthologs	Dpse\GA11251
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL009399-PA Aedes aegypti (mosquito) AGAP011887-PA Anopheles gambiae (mosquito) XP_396788.2 Apis mellifera (honey bee) 87811 Batrachochytrium dendrobatidis (chytrid fungus) 114714 Branchiostoma floridae (lancelet) 275128 Branchiostoma floridae (lancelet) ENSBTAP00000000024 Bos taurus (bovine) ENSCAFP00000010802 Canis familiaris (dog) ENSCINP00000022069 Ciona intestinalis (sea squirt) CPIJ015644 Culex pipens (mosquito) ENSCPOP00000010701 Cavia porcellus (guinea pig) ENSCSAVP00000016830 Ciona savignyi (sedentary tunicate) 148448 Capitella spl (polychaete worm) 301590 Daphnia pulex (daphnia) ENSDARP00000018434 Danio rerio (zebra fish) ENSECAP00000012919 Equus caballus (horse) ENSGACP00000026478 Gymnopilus aculeatus (mushroom) ENSGALP00000020792 Gallus gallus (chicken) 168949 Hypsipyla robusta (cedar shoot borer) ENSP00000251074 Homo sapiens (human) ISCW021169-PA Ixodes scapularis (deer tick) 203162 Lottia gigantea (owl limpet) ENSMODP00000003105 Monodelphis domestica (gray opossum) ENSMMUP00000007276 Macaca mulatta (rhesus monkey) ENSMUSP00000059880 Mus musculus (house mouse) 242089 Nematostella vectensis (starlet anemone) XP_001606460.1 Nasonia vitripennis (wasp) ENSOANP00000008853 Ornithorynchus anatinus (platypus) ENSORLP00000020626 Oryzias latipes (japanese killifish) PHUM006620-PA Pediculus humanus (human body louse) ENSPPYP00000005569 Pongo pygmaeus (orangutan) ENSPTRP00000009111 Pan troglodytes (chimpanzee) ENSRNOP00000006760 Rattus norvegicus (norway rat) SPAC4F10.18 Schizosaccharomyces pombe (fission yeast) XP_001813546.1 Tribolium castaneum (red flour beetle) ENSTNIP00000015639 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000036901 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000005395 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18849 NV17589 NV15703 LH23361 ISCW021169 FBgn0240751 FBgn0214960 FBgn0211070 FBgn0192643 FBgn0184994 FBgn0172731 JGI_V11_301590 FBgn0071305 FBgn0149598 FBgn0146616 FBgn0124824 FBgn0103681 FBgn0094573 CPIJ015644 GB10934 AGAP011887 AAEL009399 PHUM088070 GLEAN_07691
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	25453 w1118; Mi{ET1}CG11875MB05519
VDRC	v16342 w1118; P{GD7413}v16342
Genomic Clones ( 3 )
	BACR06L08 BACR10P10 BACR17E12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 44 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD22926
Other clones	DPiM_SD22926
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT12545 SD06410 SD19078
Other clones	43204 45264 59484 Dmel_dig_003053_0667_2515 Dmel_neb_015996_0832_0531 EC259094 EK161217 EK186226 EN02101 RP004042699 RP004042898 RP004050720 RP004067839 RP004075077 RP004089885 RP004096939 RP004131489 RP004198186 RP004210677 RP004218872 RP004220645 RP004229436 RP004237211 RP004240062 RP004240571 RP004244562 RP004249221 RP004250295 RP004256908 RP004257684 RP004323868 RP004337041 RP004349629 RP004388390 RP004425369 RP004488412 RP004494089 RP004517712 RP004549127
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039301 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43040
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143103 RefSeq (Proteins) • NP_651360 DDBJ / EMBL / GenBank • AAF56429 BI640129 Entrez Gene - A searchable database of RefSeq genes. • 43040 UniProtKB/TrEMBL • Q9VBU8
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • WD40 repeat (IPR001680) WD40 repeat-like-containing domain (IPR011046) WD40-repeat-containing domain (IPR017986) WD40/YVTN repeat-like-containing domain (IPR015943) WD40 repeat, subgroup (IPR019781) WD40 repeat 2 (IPR019782)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039301 DroID - A comprehensive database of gene and protein interactions. • FBgn0039301 DRSC - Results from RNAi screens. • FBgn0039301 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039301 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11875-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039301 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43040 InParanoid A subset of ortholog calls from InParanoid. • AAEL009399-PA Aedes aegypti (mosquito) AGAP011887-PA Anopheles gambiae (mosquito) XP_396788.2 Apis mellifera (honey bee) 87811 Batrachochytrium dendrobatidis (chytrid fungus) 114714 Branchiostoma floridae (lancelet) 275128 Branchiostoma floridae (lancelet) ENSBTAP00000000024 Bos taurus (bovine) ENSCAFP00000010802 Canis familiaris (dog) ENSCINP00000022069 Ciona intestinalis (sea squirt) CPIJ015644 Culex pipens (mosquito) ENSCPOP00000010701 Cavia porcellus (guinea pig) ENSCSAVP00000016830 Ciona savignyi (sedentary tunicate) 148448 Capitella spl (polychaete worm) 301590 Daphnia pulex (daphnia) ENSDARP00000018434 Danio rerio (zebra fish) ENSECAP00000012919 Equus caballus (horse) ENSGACP00000026478 Gymnopilus aculeatus (mushroom) ENSGALP00000020792 Gallus gallus (chicken) 168949 Hypsipyla robusta (cedar shoot borer) ENSP00000251074 Homo sapiens (human) ISCW021169-PA Ixodes scapularis (deer tick) 203162 Lottia gigantea (owl limpet) ENSMODP00000003105 Monodelphis domestica (gray opossum) ENSMMUP00000007276 Macaca mulatta (rhesus monkey) ENSMUSP00000059880 Mus musculus (house mouse) 242089 Nematostella vectensis (starlet anemone) XP_001606460.1 Nasonia vitripennis (wasp) ENSOANP00000008853 Ornithorynchus anatinus (platypus) ENSORLP00000020626 Oryzias latipes (japanese killifish) PHUM006620-PA Pediculus humanus (human body louse) ENSPPYP00000005569 Pongo pygmaeus (orangutan) ENSPTRP00000009111 Pan troglodytes (chimpanzee) ENSRNOP00000006760 Rattus norvegicus (norway rat) SPAC4F10.18 Schizosaccharomyces pombe (fission yeast) XP_001813546.1 Tribolium castaneum (red flour beetle) ENSTNIP00000015639 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000036901 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000005395 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43040 modMine - Data generated by the modENCODE project. • FBgn0039301 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18849 NV17589 NV15703 LH23361 ISCW021169 FBgn0240751 FBgn0214960 FBgn0211070 FBgn0192643 FBgn0184994 FBgn0172731 JGI_V11_301590 FBgn0071305 FBgn0149598 FBgn0146616 FBgn0124824 FBgn0103681 FBgn0094573 CPIJ015644 GB10934 AGAP011887 AAEL009399 PHUM088070 GLEAN_07691
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG11875 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 13 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Bellen, 2008.8.29, set806.xml set806.xml [FBrf0205581] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	DrosDel Project, 2008.11.14, Deletion FDD-0247627. Deletion FDD-0247627. [FBrf0206147] DrosDel Project, 2008.11.14, Deletion FDD-0089346. Deletion FDD-0089346. [FBrf0206145] DrosDel Project, 2008.11.14, Deletion FDD-0247625. Deletion FDD-0247625. [FBrf0206146] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]