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Gene Dmel\CG5116

General Information
Symbol	Dmel\CG5116	Species	D. melanogaster
Name		Annotation symbol	CG5116
Feature type	protein_coding_gene	FlyBase ID	FBgn0039339
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	96E2-96E2	Sequence location	3R:21,309,030..21,311,577 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5116 (FBgn0039339). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTP binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: GTP-binding domain, HSR1-related; GTP-binding protein, HflX. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult crop. Comments on Affy2 ProbeSet: ProbeSet 1628971_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG5116. Gene sequence location is 3R:21309030..21311577.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN22441 HFA15720
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 96E2-96E2   Limits computationally determined from genome sequence between P{PZ}Aats-gln05461 and P{EP}EP3354
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5116 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.43
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5116-RA FBtr0084877  NM_143142   2377   526
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5116-PA   FBpp0084251   59.2   526   9.01     NP_651399   AAF56472
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • GTP-binding domain, HSR1-related (IPR002917) GTP-binding protein, HflX (IPR016496)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF56472   AY071626 AAL49248   BI484390   BI485200   BT088847   CK657409   CO179162   EC081252   EC224031   EC230914   EV578726   EV581314
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SYD1 Q9VBQ7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039339    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039339 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039339 expression level Developmental Stage   Expression Level embryo 00-02hr    1919 embryo 02-04hr    866 embryo 04-06hr    1116 embryo 06-08hr    706 embryo 08-10hr    647 embryo 10-12hr    838 embryo 12-14hr    768 embryo 14-16hr    942 embryo 16-18hr    779 embryo 18-20hr    474 embryo 20-22hr    376 embryo 22-24hr    424 larva L1    1023 larva L2    1150 larva L3 12hr old    947 larva L3 puffstage 1-2    530 larva L3 puffstage 3-6    477 larva L3 puffstage 7-9    496 white prepupae new    428 white prepupae 12hr    440 white prepupae 24hr    569 pupae 2d postWPP    911 pupae 3d postWPP    1162 pupae 4d postWPP    1204 adult male 01day    1244 adult male 05day    1159 adult male 30day    1071 adult female 01day    1514 adult female 05day    1557 adult female 30day    1646 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1919) embryo 02-04hr  (866) embryo 04-06hr  (1116) embryo 06-08hr  (706) embryo 08-10hr  (647) embryo 10-12hr  (838) embryo 12-14hr  (768) embryo 14-16hr  (942) embryo 16-18hr  (779) embryo 18-20hr  (474) embryo 20-22hr  (376) embryo 22-24hr  (424) larva L1  (1023) larva L2  (1150) larva L3 12hr old  (947) larva L3 puffstage 1-2  (530) larva L3 puffstage 3-6  (477) larva L3 puffstage 7-9  (496) white prepupae new  (428) white prepupae 12hr  (440) white prepupae 24hr  (569) pupae 2d postWPP  (911) pupae 3d postWPP  (1162) pupae 4d postWPP  (1204) adult male 01day  (1244) adult male 05day  (1159) adult male 30day  (1071) adult female 01day  (1514) adult female 05day  (1557) adult female 30day  (1646) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1919) embryo 02-04hr    866 embryo 04-06hr    1116 embryo 06-08hr    706 embryo 08-10hr    647 embryo 10-12hr    838 embryo 12-14hr    768 embryo 14-16hr    942 embryo 16-18hr    779 embryo 18-20hr    474 embryo 20-22hr    376 embryo 22-24hr    424 larva L1    1023 larva L2    1150 larva L3 12hr old    947 larva L3 puffstage 1-2    530 larva L3 puffstage 3-6    477 larva L3 puffstage 7-9    496 white prepupae new    428 white prepupae 12hr    440 white prepupae 24hr    569 pupae 2d postWPP    911 pupae 3d postWPP    1162 pupae 4d postWPP    1204 adult male 01day    1244 adult male 05day    1159 adult male 30day    1071 adult female 01day  (1514) adult female 05day  (1557) adult female 30day  (1646) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1919 embryo 02-04hr    866 embryo 04-06hr    1116 embryo 06-08hr    706 embryo 08-10hr    647 embryo 10-12hr    838 embryo 12-14hr    768 embryo 14-16hr    942 embryo 16-18hr    779 embryo 18-20hr    474 embryo 20-22hr    376 embryo 22-24hr    424 larva L1    1023 larva L2    1150 larva L3 12hr old    947 larva L3 puffstage 1-2    530 larva L3 puffstage 3-6    477 larva L3 puffstage 7-9    496 white prepupae new    428 white prepupae 12hr    440 white prepupae 24hr    569 pupae 2d postWPP    911 pupae 3d postWPP    1162 pupae 4d postWPP    1204 adult male 01day    1244 adult male 05day    1159 adult male 30day    1071 adult female 01day    1514 adult female 05day    1557 adult female 30day    1646 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1919 embryo 02-04hr    866 embryo 04-06hr    1116 embryo 06-08hr    706 embryo 08-10hr    647 embryo 10-12hr    838 embryo 12-14hr    768 embryo 14-16hr    942 embryo 16-18hr    779 embryo 18-20hr    474 embryo 20-22hr    376 embryo 22-24hr    424 larva L1    1023 larva L2    1150 larva L3 12hr old    947 larva L3 puffstage 1-2    530 larva L3 puffstage 3-6    477 larva L3 puffstage 7-9    496 white prepupae new    428 white prepupae 12hr    440 white prepupae 24hr    569 pupae 2d postWPP    911 pupae 3d postWPP    1162 pupae 4d postWPP    1204 adult male 01day    1244 adult male 05day    1159 adult male 30day    1071 adult female 01day    1514 adult female 05day    1557 adult female 30day    1646 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039339 expression level Developmental Stage   Expression Level embryo 00-02hr    1919 embryo 02-04hr    866 embryo 04-06hr    1116 embryo 06-08hr    706 embryo 08-10hr    647 embryo 10-12hr    838 embryo 12-14hr    768 embryo 14-16hr    942 embryo 16-18hr    779 embryo 18-20hr    474 embryo 20-22hr    376 embryo 22-24hr    424 larva L1    1023 larva L2    1150 larva L3 12hr old    947 larva L3 puffstage 1-2    530 larva L3 puffstage 3-6    477 larva L3 puffstage 7-9    496 white prepupae new    428 white prepupae 12hr    440 white prepupae 24hr    569 pupae 2d postWPP    911 pupae 3d postWPP    1162 pupae 4d postWPP    1204 adult male 01day    1244 adult male 05day    1159 adult male 30day    1071 adult female 01day    1514 adult female 05day    1557 adult female 30day    1646 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1919) embryo 02-04hr  (866) embryo 04-06hr  (1116) embryo 06-08hr  (706) embryo 08-10hr  (647) embryo 10-12hr  (838) embryo 12-14hr  (768) embryo 14-16hr  (942) embryo 16-18hr  (779) embryo 18-20hr  (474) embryo 20-22hr  (376) embryo 22-24hr  (424) larva L1  (1023) larva L2  (1150) larva L3 12hr old  (947) larva L3 puffstage 1-2  (530) larva L3 puffstage 3-6  (477) larva L3 puffstage 7-9  (496) white prepupae new  (428) white prepupae 12hr  (440) white prepupae 24hr  (569) pupae 2d postWPP  (911) pupae 3d postWPP  (1162) pupae 4d postWPP  (1204) adult male 01day  (1244) adult male 05day  (1159) adult male 30day  (1071) adult female 01day  (1514) adult female 05day  (1557) adult female 30day  (1646) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1919 embryo 02-04hr    866 embryo 04-06hr    1116 embryo 06-08hr    706 embryo 08-10hr    647 embryo 10-12hr    838 embryo 12-14hr    768 embryo 14-16hr    942 embryo 16-18hr    779 embryo 18-20hr    474 embryo 20-22hr    376 embryo 22-24hr    424 larva L1    1023 larva L2    1150 larva L3 12hr old    947 larva L3 puffstage 1-2    530 larva L3 puffstage 3-6    477 larva L3 puffstage 7-9    496 white prepupae new    428 white prepupae 12hr    440 white prepupae 24hr    569 pupae 2d postWPP    911 pupae 3d postWPP    1162 pupae 4d postWPP    1204 adult male 01day    1244 adult male 05day    1159 adult male 30day    1071 adult female 01day  1514 adult female 05day  1557 adult female 30day  1646 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1919 embryo 02-04hr    866 embryo 04-06hr    1116 embryo 06-08hr    706 embryo 08-10hr    647 embryo 10-12hr    838 embryo 12-14hr    768 embryo 14-16hr    942 embryo 16-18hr    779 embryo 18-20hr    474 embryo 20-22hr    376 embryo 22-24hr    424 larva L1    1023 larva L2    1150 larva L3 12hr old    947 larva L3 puffstage 1-2    530 larva L3 puffstage 3-6    477 larva L3 puffstage 7-9    496 white prepupae new    428 white prepupae 12hr    440 white prepupae 24hr    569 pupae 2d postWPP    911 pupae 3d postWPP    1162 pupae 4d postWPP    1204 adult male 01day    1244 adult male 05day    1159 adult male 30day    1071 adult female 01day    1514 adult female 05day    1557 adult female 30day    1646 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1919 embryo 02-04hr    866 embryo 04-06hr    1116 embryo 06-08hr    706 embryo 08-10hr    647 embryo 10-12hr    838 embryo 12-14hr    768 embryo 14-16hr    942 embryo 16-18hr    779 embryo 18-20hr    474 embryo 20-22hr    376 embryo 22-24hr    424 larva L1    1023 larva L2    1150 larva L3 12hr old    947 larva L3 puffstage 1-2    530 larva L3 puffstage 3-6    477 larva L3 puffstage 7-9    496 white prepupae new    428 white prepupae 12hr    440 white prepupae 24hr    569 pupae 2d postWPP    911 pupae 3d postWPP    1162 pupae 4d postWPP    1204 adult male 01day    1244 adult male 05day    1159 adult male 30day    1071 adult female 01day    1514 adult female 05day    1557 adult female 30day    1646 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0039339    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0039339 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult crop. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0039339 expression level Tissue   Expression Level Larval Central Nervous System    67.225 Larval Midgut    38.5 Larval Hindgut    29.3 Larval Malpighian Tubules    44.1 Larval Fat Body    20.7 Larval Salivary Gland    46.2 Larval Trachea    22.35 Larval Carcass    19.825 Adult Head    36.8 Adult Eye    33.4 Adult Brain    52.5 Adult Thoracic-Abdominal Ganglion    65.2 Adult Crop    127.5 Adult Midgut    66.3 Adult Hindgut    49.2 Adult Malpighian Tubules    47.9 Adult Fat Body    66.2 Adult Salivary Gland    30.5 Adult Heart    41.15 Adult VirginFemale Spermatheca    84.1 Adult InseminatedFemale Spermatheca    77.1 Adult Ovary    61.4 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    22.2 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    67.225 Larval Midgut    38.5 Larval Hindgut    29.3 Larval Malpighian Tubules    44.1 Larval Fat Body    20.7 Larval Salivary Gland    46.2 Larval Trachea    22.35 Larval Carcass    19.825 Adult Head    36.8 Adult Eye    33.4 Adult Brain    52.5 Adult Thoracic-Abdominal Ganglion    65.2 Adult Crop    127.5 Adult Midgut    66.3 Adult Hindgut    49.2 Adult Malpighian Tubules    47.9 Adult Fat Body    66.2 Adult Salivary Gland    30.5 Adult Heart    41.15 Adult VirginFemale Spermatheca    84.1 Adult InseminatedFemale Spermatheca    77.1 Adult Ovary    61.4 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    22.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    67.225 Larval Midgut    38.5 Larval Hindgut    29.3 Larval Malpighian Tubules    44.1 Larval Fat Body    20.7 Larval Salivary Gland    46.2 Larval Trachea    22.35 Larval Carcass    19.825 Adult Head    36.8 Adult Eye    33.4 Adult Brain    52.5 Adult Thoracic-Abdominal Ganglion    65.2 Adult Crop    127.5 Adult Midgut    66.3 Adult Hindgut    49.2 Adult Malpighian Tubules    47.9 Adult Fat Body    66.2 Adult Salivary Gland    30.5 Adult Heart    41.15 Adult VirginFemale Spermatheca    84.1 Adult InseminatedFemale Spermatheca    77.1 Adult Ovary    61.4 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    22.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    67.225 Larval Midgut    38.5 Larval Hindgut    29.3 Larval Malpighian Tubules    44.1 Larval Fat Body    20.7 Larval Salivary Gland    46.2 Larval Trachea    22.35 Larval Carcass    19.825 Adult Head    36.8 Adult Eye    33.4 Adult Brain    52.5 Adult Thoracic-Abdominal Ganglion    65.2 Adult Crop    127.5 Adult Midgut    66.3 Adult Hindgut    49.2 Adult Malpighian Tubules    47.9 Adult Fat Body    66.2 Adult Salivary Gland    30.5 Adult Heart    41.15 Adult VirginFemale Spermatheca    84.1 Adult InseminatedFemale Spermatheca    77.1 Adult Ovary    61.4 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    22.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0039339 expression level Tissue   Expression Level Larval Central Nervous System    67.225 Larval Midgut    38.5 Larval Hindgut    29.3 Larval Malpighian Tubules    44.1 Larval Fat Body    20.7 Larval Salivary Gland    46.2 Larval Trachea    22.35 Larval Carcass    19.825 Adult Head    36.8 Adult Eye    33.4 Adult Brain    52.5 Adult Thoracic-Abdominal Ganglion    65.2 Adult Crop    127.5 Adult Midgut    66.3 Adult Hindgut    49.2 Adult Malpighian Tubules    47.9 Adult Fat Body    66.2 Adult Salivary Gland    30.5 Adult Heart    41.15 Adult VirginFemale Spermatheca    84.1 Adult InseminatedFemale Spermatheca    77.1 Adult Ovary    61.4 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    22.2 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    67.225 Larval Midgut    38.5 Larval Hindgut    29.3 Larval Malpighian Tubules    44.1 Larval Fat Body    20.7 Larval Salivary Gland    46.2 Larval Trachea    22.35 Larval Carcass    19.825 Adult Head    36.8 Adult Eye    33.4 Adult Brain    52.5 Adult Thoracic-Abdominal Ganglion    65.2 Adult Crop    127.5 Adult Midgut    66.3 Adult Hindgut    49.2 Adult Malpighian Tubules    47.9 Adult Fat Body    66.2 Adult Salivary Gland    30.5 Adult Heart    41.15 Adult VirginFemale Spermatheca    84.1 Adult InseminatedFemale Spermatheca    77.1 Adult Ovary    61.4 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    22.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    67.225 Larval Midgut    38.5 Larval Hindgut    29.3 Larval Malpighian Tubules    44.1 Larval Fat Body    20.7 Larval Salivary Gland    46.2 Larval Trachea    22.35 Larval Carcass    19.825 Adult Head    36.8 Adult Eye    33.4 Adult Brain    52.5 Adult Thoracic-Abdominal Ganglion    65.2 Adult Crop    127.5 Adult Midgut    66.3 Adult Hindgut    49.2 Adult Malpighian Tubules    47.9 Adult Fat Body    66.2 Adult Salivary Gland    30.5 Adult Heart    41.15 Adult VirginFemale Spermatheca    84.1 Adult InseminatedFemale Spermatheca    77.1 Adult Ovary    61.4 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    22.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    67.225 Larval Midgut    38.5 Larval Hindgut    29.3 Larval Malpighian Tubules    44.1 Larval Fat Body    20.7 Larval Salivary Gland    46.2 Larval Trachea    22.35 Larval Carcass    19.825 Adult Head    36.8 Adult Eye    33.4 Adult Brain    52.5 Adult Thoracic-Abdominal Ganglion    65.2 Adult Crop    127.5 Adult Midgut    66.3 Adult Hindgut    49.2 Adult Malpighian Tubules    47.9 Adult Fat Body    66.2 Adult Salivary Gland    30.5 Adult Heart    41.15 Adult VirginFemale Spermatheca    84.1 Adult InseminatedFemale Spermatheca    77.1 Adult Ovary    61.4 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    22.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    36.8   NA  Eye    33.4   NA  Brain    52.5   67.225  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    65.2   NA  Crop    127.5   38.5  Midgut    66.3   29.3  Hindgut    49.2   44.1  Malpighian Tubules    47.9   20.7  Fat Body    66.2   46.2  Salivary Gland    30.5   NA  Heart    41.15   22.35  Trachea    NA   NA  VirginFemale Spermatheca    84.1   NA  InseminatedFemale Spermatheca    77.1   NA  Ovary    61.4   NA  Testis    no informative data   NA  Male Accessory Gland    no informative data   19.825  Carcass    22.2 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_26
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039339 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5116-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG5116GD6267 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG5116 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5116 Class Mutagen Stocks Known lesion CG5116GD6267 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG5116KK102375 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6202 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6267} NA P{KK102375} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{GSV1}EP-51 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
GTP binding inferred from sequence or structural similarity with EMBL:Y14391 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5116 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0039339
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17695 Dere\GG11408 Dgri\GH18978 Dmoj\GI22404 Dper\GL22142 Dpse\GA18671 Dsec\GM10247 Dsim\GD21220 Dvir\GJ10964 Dwil\GK13306 Dyak\GE23604
Curated drosophilid orthologs	Dpse\GA18671
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL008133-PA Aedes aegypti (mosquito) AGAP003969-PA Anopheles gambiae (mosquito) XP_394260.2 Apis mellifera (honey bee) XP_001946111.1 Acyrthosiphon pisum (pea aphid) At5g57960.1 Arabidopsis thaliana (wall cress) 64000 Branchiostoma floridae (lancelet) XP_001893946.1 Brugia malayi (roundworm nematode) CN11621 Caenorhabditis brenneri (small nematode) CE05870 Caenorhabditis elegans (worm) ENSCAFP00000016099 Canis familiaris (dog) ENSCINP00000023840 Ciona intestinalis (sea squirt) JA14745 Caenorhabditis japonica (nematode) CMT373C Cyanidioschyzon merolae (red alga) CPIJ007256 Culex pipens (mosquito) 107789 Chlamidomonas reinhardtii (green alga) RP39823 Caenorhabditis remanei (nematode) ENSCSAVP00000015721 Ciona savignyi (sedentary tunicate) 93416 Capitella spl (polychaete worm) 46890 Daphnia pulex (daphnia) ENSDARP00000081167 Danio rerio (zebra fish) NP_418594.1 Escherichia coli K12 (bacteria) ENSGACP00000018301 Gymnopilus aculeatus (mushroom) ENSGALP00000026928 Gallus gallus (chicken) 186232 Hypsipyla robusta (cedar shoot borer) ENSP00000383537 Homo sapiens (human) 113712 Lottia gigantea (owl limpet) 22354 Monocosta brevicollis (choanoflagellate) ENSMODP00000000388 Monodelphis domestica (gray opossum) ENSMMUP00000018260 Macaca mulatta (rhesus monkey) ENSMUSP00000076458 Mus musculus (house mouse) 198618 Nematostella vectensis (starlet anemone) XP_001604860.1 Nasonia vitripennis (wasp) ENSOANP00000011164 Ornithorynchus anatinus (platypus) ENSORLP00000020117 Oryzias latipes (japanese killifish) LOC_Os11g38020.1 Oryza sativa (asian rice) 18000 Ostreococcus tauri (green alga) PF11_0143 Plasmodium falciparum (protozoal parasite) PHUM007544-PA Pediculus humanus (human body louse) 138684 Physcomitrella patens (moss) ENSPPYP00000022450 Pongo pygmaeus (orangutan) 563330 Populus trichocarpa (black cottonwood) PVX_091320 Plasmodium vivax (protozoal parasite) ENSRNOP00000053471 Rattus norvegicus (norway rat) 5056709 Sorghum bicolor (sorghum) Smp_016550.2 Schistosoma mansoni (trematode parasite) XP_798244.2 Strongylocentrotus purpuratus (purple sea urchin) 18641 Trichoplax adhaerens (metazoa) XP_972507.2 Tribolium castaneum (red flour beetle) ENSTNIP00000013574 Tetraodon nigroviridis (green spotted pufferfish) 42307 Thalassiosira pseudonana (marine diatom) ENSTRUP00000028206 Takifugu rubripes (pufferfish Takifugu) 3828.m01312 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000008922 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15323 LH24029 ISCW014716 FBgn0240777 FBgn0215315 FBgn0198232 FBgn0192671 FBgn0165198 JGI_V11_46890 FBgn0078671 FBgn0159734 FBgn0145132 FBgn0126445 FBgn0103708 FBgn0094713 CPIJ007256 ACYPI002236 GB16691 AGAP003969 AAEL008133 PB25112 PHUM210680 GLEAN_05168
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v106458 P{KK102375}VIE-260B v16476 w1118; P{GD6267}v16476 v17252 w1118; P{GD6267}v17252
Genomic Clones ( 2 )
	BACR03M22 BACR03O03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 10 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE67480
Other clones	FI04601
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP23666 RE68488
Other clones	70868 CK01.74D.A12 CK01.75C.A2 Dmel_dig_005064_0687_3637 Dmel_dig_018984_0631_2801 EK058636
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039339 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43081
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143142 RefSeq (Proteins) • NP_651399 DDBJ / EMBL / GenBank • AAF56472 AAL49248 AY071626 BI484390 Entrez Gene - A searchable database of RefSeq genes. • 43081 UniProtKB/TrEMBL • Q8SYD1 Q9VBQ7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • GTP-binding domain, HSR1-related (IPR002917) GTP-binding protein, HflX (IPR016496)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0039339 DRSC - Results from RNAi screens. • FBgn0039339 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039339 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5116-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039339 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43081 InParanoid A subset of ortholog calls from InParanoid. • AAEL008133-PA Aedes aegypti (mosquito) AGAP003969-PA Anopheles gambiae (mosquito) XP_394260.2 Apis mellifera (honey bee) XP_001946111.1 Acyrthosiphon pisum (pea aphid) At5g57960.1 Arabidopsis thaliana (wall cress) 64000 Branchiostoma floridae (lancelet) XP_001893946.1 Brugia malayi (roundworm nematode) CN11621 Caenorhabditis brenneri (small nematode) CE05870 Caenorhabditis elegans (worm) ENSCAFP00000016099 Canis familiaris (dog) ENSCINP00000023840 Ciona intestinalis (sea squirt) JA14745 Caenorhabditis japonica (nematode) CMT373C Cyanidioschyzon merolae (red alga) CPIJ007256 Culex pipens (mosquito) 107789 Chlamidomonas reinhardtii (green alga) RP39823 Caenorhabditis remanei (nematode) ENSCSAVP00000015721 Ciona savignyi (sedentary tunicate) 93416 Capitella spl (polychaete worm) 46890 Daphnia pulex (daphnia) ENSDARP00000081167 Danio rerio (zebra fish) NP_418594.1 Escherichia coli K12 (bacteria) ENSGACP00000018301 Gymnopilus aculeatus (mushroom) ENSGALP00000026928 Gallus gallus (chicken) 186232 Hypsipyla robusta (cedar shoot borer) ENSP00000383537 Homo sapiens (human) 113712 Lottia gigantea (owl limpet) 22354 Monocosta brevicollis (choanoflagellate) ENSMODP00000000388 Monodelphis domestica (gray opossum) ENSMMUP00000018260 Macaca mulatta (rhesus monkey) ENSMUSP00000076458 Mus musculus (house mouse) 198618 Nematostella vectensis (starlet anemone) XP_001604860.1 Nasonia vitripennis (wasp) ENSOANP00000011164 Ornithorynchus anatinus (platypus) ENSORLP00000020117 Oryzias latipes (japanese killifish) LOC_Os11g38020.1 Oryza sativa (asian rice) 18000 Ostreococcus tauri (green alga) PF11_0143 Plasmodium falciparum (protozoal parasite) PHUM007544-PA Pediculus humanus (human body louse) 138684 Physcomitrella patens (moss) ENSPPYP00000022450 Pongo pygmaeus (orangutan) 563330 Populus trichocarpa (black cottonwood) PVX_091320 Plasmodium vivax (protozoal parasite) ENSRNOP00000053471 Rattus norvegicus (norway rat) 5056709 Sorghum bicolor (sorghum) Smp_016550.2 Schistosoma mansoni (trematode parasite) XP_798244.2 Strongylocentrotus purpuratus (purple sea urchin) 18641 Trichoplax adhaerens (metazoa) XP_972507.2 Tribolium castaneum (red flour beetle) ENSTNIP00000013574 Tetraodon nigroviridis (green spotted pufferfish) 42307 Thalassiosira pseudonana (marine diatom) ENSTRUP00000028206 Takifugu rubripes (pufferfish Takifugu) 3828.m01312 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000008922 Xenopus tropicalis (frog) modMine - Data generated by the modENCODE project. • FBgn0039339 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15323 LH24029 ISCW014716 FBgn0240777 FBgn0215315 FBgn0198232 FBgn0192671 FBgn0165198 JGI_V11_46890 FBgn0078671 FBgn0159734 FBgn0145132 FBgn0126445 FBgn0103708 FBgn0094713 CPIJ007256 ACYPI002236 GB16691 AGAP003969 AAEL008133 PB25112 PHUM210680 GLEAN_05168
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG5116 (Molnar et al., 2006, Bassett et al., 2008, Hayden and Bosco, 2008, Keleman et al., 2009.8.5, Wasbrough et al., 2010) Dromel_CG5116_FBtr0084877_mORF (Hayden and Bosco, 2008)
Name Synonym
Secondary FlyBase IDs
References ( 15 )
Research paper	Bassett et al., 2008, PLoS ONE 3(5): e2099 The Chromatin Remodelling Factor dATRX Is Involved in Heterochromatin Formation. [FBrf0206630] Hayden and Bosco, 2008, BMC Genomics 9: 61 Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran species. [FBrf0204849] Molnar et al., 2006, Genetics 174(3): 1635--1659 A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. [FBrf0195387]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Wasbrough et al., 2010, J. Proteomics 73(11): Supplemental Table 1. Mass spectrometry data. [FBrf0213252] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Hayden and Bosco, 2008, BMC Genomics: File 1: Conserved peptide uORF and associated mORF amino acid sequences in Drosophila melanogaster. [FBrf0205942]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Roth and Foulger, 2002.4.24, Predicted GO terms. Predicted GO terms. [FBrf0146674]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]