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Gene Dmel\CG5112

General Information
Symbol	Dmel\CG5112	Species	D. melanogaster
Name		Annotation symbol	CG5112
Feature type	protein_coding_gene	FlyBase ID	FBgn0039341
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	96E2-96E2	Sequence location	3R:21,317,182..21,318,984 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5112 (FBgn0039341). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: fatty acid amide hydrolase activity. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Amidase; Amidase signature domain; Amidase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult crop, adult heart, adult fat body, larval/adult salivary gland, adult male accessory gland, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval trachea, adult female reproductive system, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1625683_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG5112. Gene sequence location is 3R:21317182..21318984.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 96E2-96E2   Limits computationally determined from genome sequence between P{PZ}Aats-gln05461 and P{EP}EP3354
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5112 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.48
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5112-RA FBtr0084878  NM_143143   1803   523
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5112-PA   FBpp0084252   58.5   523   8.45     NP_651400   AAF56474
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Amidase (IPR000120) Amidase signature domain (IPR023631) Amidase, conserved site (IPR020556)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA697151   AA821068   AE014297 AAF56474   AI402766   AI515003   AI518136   AI518730   AW943423   AY058674 AAL13903   BF489632   BF490106   BF494120   BF495978   BF496401   BF496899   BF501497   BF503319   BF506608   BI163386   BI229830   BI368919   BI617179   BI623368   BP542520   CK658530   CL610097   CO178126   CO287242   CO316017   CO319067   EC195751   EC203974   EC228406   EC238995   EV582245   EV585078   EV588721   EV592728   GH749531   GH750100   GH751109   GH752286   GH752298   GH755274   GH757296   GH758874   GH760538   GH760703   GH774277   GH776839   GH781448   GH786999   GH788078   GH789361   GH789544   GH792513   GH792774   GH793539   GH796798   GH798230   GH799568   GH800324   GH800408   GH800652   GH801834   GH809502   GH811282   GH811591   GH813881   GH815676   GH815820   GH815825   GH815992   GH816887   GH818902   GH820190   GH821308   GH825810   GH825998   GH827175   GH830979   GH831738   GH837913   GH841582   GH846501   GH846767   GH846912   GH858705   GH861705   GH867882   GH870270   GH871953   GH878659   GH878795   GH884912   GH885855   GH890690   GH890699   GH891659   GH894526   GH903089   GH904977   GH905873   GH908812   GH911392   GH911584   GH912111   GH913374   GH913919   GH915560   GH915811   GH916169   GH918501   GH920937   GH923851   GH924235   GH926176   GH929240   GH930020   GH940542
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VBQ5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
lipid particle inferred from direct assay (Cermelli et al., 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult crop, adult heart, adult fat body, larval/adult salivary gland, adult male accessory gland, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval trachea, adult female reproductive system, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    129.175 Larval Midgut    241.8 Larval Hindgut    211.3 Larval Malpighian Tubules    422.8 Larval Fat Body    94.6 Larval Salivary Gland    651.8 Larval Trachea    261.3 Larval Carcass    396.65 Adult Head    121.3 Adult Eye    163.325 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    86.9 Adult Crop    550.2 Adult Midgut    148.1 Adult Hindgut    245.4 Adult Malpighian Tubules    423.7 Adult Fat Body    677.8 Adult Salivary Gland    517.6 Adult Heart    770.775 Adult VirginFemale Spermatheca    93.9 Adult InseminatedFemale Spermatheca    118.2 Adult Ovary    238.3 Adult Testis    89 Adult Male Accessory Gland    1103.5 Adult Carcass    508.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    129.175 Larval Midgut    241.8 Larval Hindgut    211.3 Larval Malpighian Tubules    422.8 Larval Fat Body    94.6 Larval Salivary Gland  (651.8) Larval Trachea    261.3 Larval Carcass    396.65 Adult Head    121.3 Adult Eye    163.325 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    86.9 Adult Crop  (550.2) Adult Midgut    148.1 Adult Hindgut    245.4 Adult Malpighian Tubules    423.7 Adult Fat Body  (677.8) Adult Salivary Gland  517.6 Adult Heart  (770.775) Adult VirginFemale Spermatheca    93.9 Adult InseminatedFemale Spermatheca    118.2 Adult Ovary    238.3 Adult Testis    89 Adult Male Accessory Gland  (1103.5) Adult Carcass  508.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    129.175 Larval Midgut    241.8 Larval Hindgut    211.3 Larval Malpighian Tubules    422.8 Larval Fat Body    94.6 Larval Salivary Gland    651.8 Larval Trachea    261.3 Larval Carcass    396.65 Adult Head    121.3 Adult Eye    163.325 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    86.9 Adult Crop    550.2 Adult Midgut    148.1 Adult Hindgut    245.4 Adult Malpighian Tubules    423.7 Adult Fat Body    677.8 Adult Salivary Gland    517.6 Adult Heart    770.775 Adult VirginFemale Spermatheca    93.9 Adult InseminatedFemale Spermatheca    118.2 Adult Ovary    238.3 Adult Testis    89 Adult Male Accessory Gland  (1103.5) Adult Carcass    508.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    129.175 Larval Midgut    241.8 Larval Hindgut    211.3 Larval Malpighian Tubules    422.8 Larval Fat Body    94.6 Larval Salivary Gland    651.8 Larval Trachea    261.3 Larval Carcass    396.65 Adult Head    121.3 Adult Eye    163.325 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    86.9 Adult Crop    550.2 Adult Midgut    148.1 Adult Hindgut    245.4 Adult Malpighian Tubules    423.7 Adult Fat Body    677.8 Adult Salivary Gland    517.6 Adult Heart    770.775 Adult VirginFemale Spermatheca    93.9 Adult InseminatedFemale Spermatheca    118.2 Adult Ovary    238.3 Adult Testis    89 Adult Male Accessory Gland    1103.5 Adult Carcass    508.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    129.175 Larval Midgut    241.8 Larval Hindgut    211.3 Larval Malpighian Tubules    422.8 Larval Fat Body    94.6 Larval Salivary Gland    651.8 Larval Trachea    261.3 Larval Carcass    396.65 Adult Head    121.3 Adult Eye    163.325 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    86.9 Adult Crop    550.2 Adult Midgut    148.1 Adult Hindgut    245.4 Adult Malpighian Tubules    423.7 Adult Fat Body    677.8 Adult Salivary Gland    517.6 Adult Heart    770.775 Adult VirginFemale Spermatheca    93.9 Adult InseminatedFemale Spermatheca    118.2 Adult Ovary    238.3 Adult Testis    89 Adult Male Accessory Gland    1103.5 Adult Carcass    508.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    129.175 Larval Midgut    241.8 Larval Hindgut    211.3 Larval Malpighian Tubules    422.8 Larval Fat Body    94.6 Larval Salivary Gland  651.8 Larval Trachea    261.3 Larval Carcass    396.65 Adult Head    121.3 Adult Eye    163.325 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    86.9 Adult Crop  550.2 Adult Midgut    148.1 Adult Hindgut    245.4 Adult Malpighian Tubules    423.7 Adult Fat Body  677.8 Adult Salivary Gland  517.6 Adult Heart  770.775 Adult VirginFemale Spermatheca    93.9 Adult InseminatedFemale Spermatheca    118.2 Adult Ovary    238.3 Adult Testis    89 Adult Male Accessory Gland  (1103.5) Adult Carcass  508.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    129.175 Larval Midgut    241.8 Larval Hindgut    211.3 Larval Malpighian Tubules    422.8 Larval Fat Body    94.6 Larval Salivary Gland    651.8 Larval Trachea    261.3 Larval Carcass    396.65 Adult Head    121.3 Adult Eye    163.325 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    86.9 Adult Crop    550.2 Adult Midgut    148.1 Adult Hindgut    245.4 Adult Malpighian Tubules    423.7 Adult Fat Body    677.8 Adult Salivary Gland    517.6 Adult Heart    770.775 Adult VirginFemale Spermatheca    93.9 Adult InseminatedFemale Spermatheca    118.2 Adult Ovary    238.3 Adult Testis    89 Adult Male Accessory Gland  1103.5 Adult Carcass    508.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    129.175 Larval Midgut    241.8 Larval Hindgut    211.3 Larval Malpighian Tubules    422.8 Larval Fat Body    94.6 Larval Salivary Gland    651.8 Larval Trachea    261.3 Larval Carcass    396.65 Adult Head    121.3 Adult Eye    163.325 Adult Brain    74 Adult Thoracic-Abdominal Ganglion    86.9 Adult Crop    550.2 Adult Midgut    148.1 Adult Hindgut    245.4 Adult Malpighian Tubules    423.7 Adult Fat Body    677.8 Adult Salivary Gland    517.6 Adult Heart    770.775 Adult VirginFemale Spermatheca    93.9 Adult InseminatedFemale Spermatheca    118.2 Adult Ovary    238.3 Adult Testis    89 Adult Male Accessory Gland    1103.5 Adult Carcass    508.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    121.3   NA  Eye    163.325   NA  Brain    74   129.175  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    86.9   NA  Crop    550.2   241.8  Midgut    148.1   211.3  Hindgut    245.4   422.8  Malpighian Tubules    423.7   94.6  Fat Body    677.8   651.8  Salivary Gland    517.6   NA  Heart    770.775   261.3  Trachea    NA   NA  VirginFemale Spermatheca    93.9   NA  InseminatedFemale Spermatheca    118.2   NA  Ovary    238.3   NA  Testis    89   NA  Male Accessory Gland    1103.5   396.65  Carcass    508.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    17 central nervous system, pupae P8    11 head, virgin 1-day female    18 head, virgin 4-day female    10 head, virgin 20-day female    12 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    20 head, mated 4-day male    19 head, mated 20-day male    27 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    26 digestive system, 4-day adult    22 digestive system, 20-day adult    25 fat body, larvae L3 wandering    7 fat body, white prepupae    8 fat body, pupae P8    42 carcass, larvae L3 wandering    32 carcass, 1-day adult    32 carcass, 4-day adult    41 carcass, 20-day adult    47 ovary, virgin 4-day female    38 ovary, mated 4-day female    36 testis, mated 4-day male    28 accessory gland, mated 4-day male    66 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (30) central nervous system, larvae L3    17 central nervous system, pupae P8    11 head, virgin 1-day female    18 head, virgin 4-day female    10 head, virgin 20-day female    12 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    20 head, mated 4-day male    19 head, mated 20-day male  (27) salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    14 digestive system, 1-day adult  26 digestive system, 4-day adult    22 digestive system, 20-day adult    25 fat body, larvae L3 wandering    7 fat body, white prepupae    8 fat body, pupae P8  (42) carcass, larvae L3 wandering  (32) carcass, 1-day adult  (32) carcass, 4-day adult  (41) carcass, 20-day adult  (47) ovary, virgin 4-day female  (38) ovary, mated 4-day female  (36) testis, mated 4-day male  (28) accessory gland, mated 4-day male  (66) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    17 central nervous system, pupae P8    11 head, virgin 1-day female    18 head, virgin 4-day female    10 head, virgin 20-day female    12 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    20 head, mated 4-day male    19 head, mated 20-day male    27 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    26 digestive system, 4-day adult    22 digestive system, 20-day adult    25 fat body, larvae L3 wandering    7 fat body, white prepupae    8 fat body, pupae P8    42 carcass, larvae L3 wandering    32 carcass, 1-day adult    32 carcass, 4-day adult    41 carcass, 20-day adult    47 ovary, virgin 4-day female    38 ovary, mated 4-day female    36 testis, mated 4-day male    28 accessory gland, mated 4-day male    66 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    17 central nervous system, pupae P8    11 head, virgin 1-day female    18 head, virgin 4-day female    10 head, virgin 20-day female    12 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    20 head, mated 4-day male    19 head, mated 20-day male    27 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    26 digestive system, 4-day adult    22 digestive system, 20-day adult    25 fat body, larvae L3 wandering    7 fat body, white prepupae    8 fat body, pupae P8    42 carcass, larvae L3 wandering    32 carcass, 1-day adult    32 carcass, 4-day adult    41 carcass, 20-day adult    47 ovary, virgin 4-day female    38 ovary, mated 4-day female    36 testis, mated 4-day male    28 accessory gland, mated 4-day male    66 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    17 central nervous system, pupae P8    11 head, virgin 1-day female    18 head, virgin 4-day female    10 head, virgin 20-day female    12 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    20 head, mated 4-day male    19 head, mated 20-day male    27 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    26 digestive system, 4-day adult    22 digestive system, 20-day adult    25 fat body, larvae L3 wandering    7 fat body, white prepupae    8 fat body, pupae P8    42 carcass, larvae L3 wandering    32 carcass, 1-day adult    32 carcass, 4-day adult    41 carcass, 20-day adult    47 ovary, virgin 4-day female    38 ovary, mated 4-day female    36 testis, mated 4-day male    28 accessory gland, mated 4-day male    66 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  30 central nervous system, larvae L3    17 central nervous system, pupae P8    11 head, virgin 1-day female    18 head, virgin 4-day female    10 head, virgin 20-day female    12 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    20 head, mated 4-day male    19 head, mated 20-day male  27 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    14 digestive system, 1-day adult  26 digestive system, 4-day adult    22 digestive system, 20-day adult    25 fat body, larvae L3 wandering    7 fat body, white prepupae    8 fat body, pupae P8  (42) carcass, larvae L3 wandering  32 carcass, 1-day adult  32 carcass, 4-day adult  (41) carcass, 20-day adult  (47) ovary, virgin 4-day female  (38) ovary, mated 4-day female  (36) testis, mated 4-day male  28 accessory gland, mated 4-day male  (66) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    17 central nervous system, pupae P8    11 head, virgin 1-day female    18 head, virgin 4-day female    10 head, virgin 20-day female    12 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    20 head, mated 4-day male    19 head, mated 20-day male    27 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    26 digestive system, 4-day adult    22 digestive system, 20-day adult    25 fat body, larvae L3 wandering    7 fat body, white prepupae    8 fat body, pupae P8    42 carcass, larvae L3 wandering    32 carcass, 1-day adult    32 carcass, 4-day adult    41 carcass, 20-day adult    47 ovary, virgin 4-day female    38 ovary, mated 4-day female    36 testis, mated 4-day male    28 accessory gland, mated 4-day male    66 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    30 central nervous system, larvae L3    17 central nervous system, pupae P8    11 head, virgin 1-day female    18 head, virgin 4-day female    10 head, virgin 20-day female    12 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    20 head, mated 4-day male    19 head, mated 20-day male    27 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    26 digestive system, 4-day adult    22 digestive system, 20-day adult    25 fat body, larvae L3 wandering    7 fat body, white prepupae    8 fat body, pupae P8    42 carcass, larvae L3 wandering    32 carcass, 1-day adult    32 carcass, 4-day adult    41 carcass, 20-day adult    47 ovary, virgin 4-day female    38 ovary, mated 4-day female    36 testis, mated 4-day male    28 accessory gland, mated 4-day male    66 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    2 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    0 adult male 01day    1 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    2 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    2 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    0 adult male 01day    1 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    2 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    2 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    0 adult male 01day    1 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    2 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    2 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    0 adult male 01day    1 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    2 adult female 30day    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    2 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    0 adult male 01day    1 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    2 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    2 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    0 adult male 01day    1 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    2 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    2 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    0 adult male 01day    1 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    2 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    2 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    0 adult male 01day    1 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    2 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    51 Schneider line 2 Sg4    49 embryonic 1182-4H    45 embryonic GM2    78 embryonic Kc167    12 embryonic S1    64 embryonic S3    46 leg disc CME L1    49 wing disc CME-W2    44 wing disc ML-DmD8    31 wing disc ML-DmD9    32 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    21 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    31 eye-antennal disc ML-DmD11    45 antennal disc ML-DmD20-c5    47 mixed discs ML-DmD4-c1    42 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    64 tumorous blood cells mbn2    48 ovary fGS/OSS    32 ovary OSC    12 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (51) Schneider line 2 Sg4  (49) embryonic 1182-4H  (45) embryonic GM2  (78) embryonic Kc167    12 embryonic S1  (64) embryonic S3  (46) leg disc CME L1  (49) wing disc CME-W2  (44) wing disc ML-DmD8  (31) wing disc ML-DmD9  (32) wing disc ML-DmD16-c3  (46) wing disc ML-DmD21    21 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3  (31) eye-antennal disc ML-DmD11  (45) antennal disc ML-DmD20-c5  (47) mixed discs ML-DmD4-c1  (42) CNS ML-DmBG1-c1  (42) CNS ML-DmBG2-c2  (64) tumorous blood cells mbn2  (48) ovary fGS/OSS  (32) ovary OSC    12 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    51 Schneider line 2 Sg4    49 embryonic 1182-4H    45 embryonic GM2    78 embryonic Kc167    12 embryonic S1    64 embryonic S3    46 leg disc CME L1    49 wing disc CME-W2    44 wing disc ML-DmD8    31 wing disc ML-DmD9    32 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    21 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    31 eye-antennal disc ML-DmD11    45 antennal disc ML-DmD20-c5    47 mixed discs ML-DmD4-c1    42 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    64 tumorous blood cells mbn2    48 ovary fGS/OSS    32 ovary OSC    12 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    51 Schneider line 2 Sg4    49 embryonic 1182-4H    45 embryonic GM2    78 embryonic Kc167    12 embryonic S1    64 embryonic S3    46 leg disc CME L1    49 wing disc CME-W2    44 wing disc ML-DmD8    31 wing disc ML-DmD9    32 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    21 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    31 eye-antennal disc ML-DmD11    45 antennal disc ML-DmD20-c5    47 mixed discs ML-DmD4-c1    42 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    64 tumorous blood cells mbn2    48 ovary fGS/OSS    32 ovary OSC    12 ovary OSS    17 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    51 Schneider line 2 Sg4    49 embryonic 1182-4H    45 embryonic GM2    78 embryonic Kc167    12 embryonic S1    64 embryonic S3    46 leg disc CME L1    49 wing disc CME-W2    44 wing disc ML-DmD8    31 wing disc ML-DmD9    32 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    21 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    31 eye-antennal disc ML-DmD11    45 antennal disc ML-DmD20-c5    47 mixed discs ML-DmD4-c1    42 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    64 tumorous blood cells mbn2    48 ovary fGS/OSS    32 ovary OSC    12 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (51) Schneider line 2 Sg4  (49) embryonic 1182-4H  (45) embryonic GM2  (78) embryonic Kc167    12 embryonic S1  (64) embryonic S3  (46) leg disc CME L1  (49) wing disc CME-W2  (44) wing disc ML-DmD8  31 wing disc ML-DmD9  32 wing disc ML-DmD16-c3  (46) wing disc ML-DmD21    21 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3  31 eye-antennal disc ML-DmD11  (45) antennal disc ML-DmD20-c5  (47) mixed discs ML-DmD4-c1  (42) CNS ML-DmBG1-c1  (42) CNS ML-DmBG2-c2  (64) tumorous blood cells mbn2  (48) ovary fGS/OSS  32 ovary OSC    12 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    51 Schneider line 2 Sg4    49 embryonic 1182-4H    45 embryonic GM2    78 embryonic Kc167    12 embryonic S1    64 embryonic S3    46 leg disc CME L1    49 wing disc CME-W2    44 wing disc ML-DmD8    31 wing disc ML-DmD9    32 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    21 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    31 eye-antennal disc ML-DmD11    45 antennal disc ML-DmD20-c5    47 mixed discs ML-DmD4-c1    42 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    64 tumorous blood cells mbn2    48 ovary fGS/OSS    32 ovary OSC    12 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    51 Schneider line 2 Sg4    49 embryonic 1182-4H    45 embryonic GM2    78 embryonic Kc167    12 embryonic S1    64 embryonic S3    46 leg disc CME L1    49 wing disc CME-W2    44 wing disc ML-DmD8    31 wing disc ML-DmD9    32 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    21 wing disc ML-DmD32    16 haltere disc ML-DmD17-c3    31 eye-antennal disc ML-DmD11    45 antennal disc ML-DmD20-c5    47 mixed discs ML-DmD4-c1    42 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    64 tumorous blood cells mbn2    48 ovary fGS/OSS    32 ovary OSC    12 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    14 heat shock, 4-day adult    41 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    36 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    31 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    23 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    49 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    14 heat shock, 4-day adult  (41) Cadmium 50 mM 6 hrs, larvae L3  (34) Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult  (36) Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3  (31) Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3  (45) Ethanol 5% 3 hrs, larvae L3  (29) Ethanol 10% 3 hrs, larvae L3  (39) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (30) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    23 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult  (36) Paraquat 10 mM 48 hrs, 4-day adult  (49) Rotenone 2 μg 12 hrs, larvae L3  (30) Rotenone 8 μg 12 hrs, larvae L3  (35) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    14 heat shock, 4-day adult    41 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    36 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    31 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    23 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    49 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    14 heat shock, 4-day adult    41 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    36 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    31 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    23 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    49 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    14 heat shock, 4-day adult    41 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    36 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    31 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    23 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    49 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    14 heat shock, 4-day adult  (41) Cadmium 50 mM 6 hrs, larvae L3  (34) Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult  (36) Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3  31 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3  (45) Ethanol 5% 3 hrs, larvae L3  29 Ethanol 10% 3 hrs, larvae L3  (39) Caffeine 1.5 mg/ml 4 hrs, larvae L3  30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    23 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult  (36) Paraquat 10 mM 48 hrs, 4-day adult  (49) Rotenone 2 μg 12 hrs, larvae L3  30 Rotenone 8 μg 12 hrs, larvae L3  (35) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    14 heat shock, 4-day adult    41 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    36 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    31 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    23 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    49 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    14 heat shock, 4-day adult    41 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    36 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    31 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    15 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    23 Caffeine 25 mg/ml 48 hrs, 4-day adult    19 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    49 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • LD38433 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039341 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5112-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG5112EY01046 viable, with Scer\GAL4pnr-MD237 CG5112GD6268 Sterility Allele fertile CG5112EY01046 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG5112 Class Mutagen Stocks Known lesion CG5112C125 1 -- CG5112EY01046 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5112 Class Mutagen Stocks Known lesion CG5112GD6268 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG5112KK110567 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CG5112NIG.5112R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6202 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6268} NA P{KK110567} NA P{NIG.5112R} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG5112EY01046 NA miscellaneous insertions P{SUPor-P}KG07684 NA PBac{3HPy+}CG5112C125 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
lipid particle inferred from direct assay (Cermelli et al., 2006)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
carbon-nitrogen ligase activity, with glutamine as amido-N-donor inferred from electronic annotation with InterPro:IPR000120 (FlyBase Curators et al., 2004-) fatty acid amide hydrolase activity inferred from sequence or structural similarity with UniProtKB:O08914 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG5112 - CG2064 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5112 - CG2065 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5112 - CG8892 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5112 - Mec2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5112 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67996 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039341 DroID - A comprehensive database of gene and protein interactions. • FBgn0039341 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43083
Orthologs
OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG63N7ZC Dipteran inclusive ortholog search EOG6SN1X1 Insect inclusive ortholog search EOG66130C Arthropod inclusive ortholog search EOG6RR4ZW Metazoa inclusive ortholog search EOG6B8X6P
Orthologs in Drosophila Species (EOG63N7ZC)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG5112     Drosophila simulans   Dsim\GD21221 Y   Drosophila sechellia   Dsec\GM10248 Y   Drosophila erecta   Dere\GG11409 Y   Drosophila yakuba   Dyak\GE23605 Y   Drosophila ananassae   Dana\GF17696 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA18668 Y   Drosophila persimilis   Dper\GL22143 Y   Drosophila willistoni   Dwil\GK12847 Y   Drosophila virilis   Dvir\GJ10965 Y   Drosophila mojavensis   Dmoj\GI22405 Y   Drosophila grimshawi   Dgri\GH18979 Y
Orthologs in non-Drosophila Dipterans (EOG6SN1X1)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001173   Anopheles gambiae Malaria mosquito  Agam\AGAP009617   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ005590
Orthologs in non-Dipteran Insects (EOG66130C)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB47832   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006154   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH23998   Atta cephalotes Leafcutter ant  Acep\ACEP24623   Camponotus floridanus Florida carpenter ant  Cflo\CFLO21422   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL16575   Linepithema humile Argentine ant  Lhum\LH18757   Pogonomyrmex barbatus Red harvester ant  Pbar\PB17163   Solenopsis invicta Red fire ant  Sinv\SINV21907   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001100   Pediculus humanus Human body louse  Phum\PHUM128650   Tribolium castaneum Red flour beetle  Tcas\TC005582
Orthologs in non-Insect Arthropods (EOG6RR4ZW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\matK Y Daphnia pulex Water flea  Dpux\JGI_V11_205366 Y Ixodes scapularis Deer tick  Isca\ISCW022298 Y Ixodes scapularis Deer tick  Isca\ISCW007174 Y
Orthologs in non-Arthropod Metazoa (EOG6B8X6P)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\Y53F4B.18 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018289gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000660gn Y Danio rerio Zebrafish  Drer\faah2a Y Danio rerio Zebrafish  Drer\faah2b Y Xenopus tropicalis Western clawed frog  Xtro\faah2 Y Homo sapiens Human  Hsap\RP11-479E16.1 Y
Human Orthologs (1)
Gene OMIM HGNC Hsap\RP11-479E16.1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD21221 Drosophila sechellia Dsec\GM10248 Drosophila erecta Dere\GG11409 Drosophila yakuba Dyak\GE23605 Drosophila ananassae Dana\GF17696 Drosophila pseudoobscura pseudoobscura Dpse\GA18668 Drosophila persimilis Dper\GL22143 Drosophila willistoni Dwil\GK12847 Drosophila virilis Dvir\GJ10965 Drosophila mojavensis Dmoj\GI22405 Drosophila grimshawi Dgri\GH18979
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	19636 y1 w67c23; P{EPgy2}CG5112EY01046 16284 y1 w1118; PBac{3HPy+}CG5112C125
VDRC	v14747 w1118; P{GD6268}v14747 v14749 w1118; P{GD6268}v14749/TM3
Genomic Clones ( 2 )
	BACR03M22 BACR03O03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 117 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD38433
Other clones	DPiM_LD38433
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT02544 AT09136 AT09677 AT10192 AT10905 AT16855 AT19279 AT25736 AT26390 GH22054 GM06152 GM09205 LD37561 LD46659 RE02767 RE27695 RE54978 RH47426 RH55589
Other clones	160519 174763 283565 CK01.69B.C5 Dmel_dig_000871_0668_0383 Dmel_dig_009456_0714_1710 Dmel_neb_010827_0650_1020 Dmel_neb_014002_0192_3160 EK055411 EK065309 EK263341 EK276139 FGC014A07 LP15508 RP003002103 RP003056954 RP003068505 RP003068515 RP003076233 RP003088848 RP003095317 RP003104207 RP003108005 RP003108402 RP003122266 RP003130908 RP003140147 RP003142026 RP003148024 RP003157189 RP003162062 RP003162712 RP003164660 RP003164761 RP003178560 RP003184136 RP003185818 RP003190449 RP003199402 RP003203418 RP003207332 RP003208255 RP003213307 RP003216102 RP003225683 RP003236918 RP003237495 RP003238398 RP003240529 RP003244996 RP003268054 RP003268688 RP003274181 RP003294634 RP003302458 RP003304132 RP003306577 RP003308673 RP003311249 RP003321308 RP003347273 RP003349686 RP003350429 RP003357606 RP003371662 RP003377000 RP003382835 RP003383921 RP003441213 RP003441404 RP003447639 RP003457354 RP003470953 RP003471671 RP003480573 RP003489368 RP003498077 RP003513506 RP003521902 RP003525395 RP003556330 RP003579030 RP003579474 RP003581987 RP003590458 RP003601556 RP003621789 RP003626699 RP003628097 RP003629032 RP003629510 RP003631012 RP003636547 RP003637318 RP003657880 RP003663646
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039341 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43083
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143143 RefSeq (Proteins) • NP_651400 DDBJ / EMBL / GenBank • AAF56474 AAL13903 AI518730 AW943423 AY058674 CL610097 Entrez Gene - A searchable database of RefSeq genes. • 43083 UniProtKB/TrEMBL • Q9VBQ5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Amidase (IPR000120) Amidase signature domain (IPR023631) Amidase, conserved site (IPR020556) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD38433
Linkouts
	BioGRID - A database of protein and genetic interactions • 67996 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039341 DroID - A comprehensive database of gene and protein interactions. • FBgn0039341 DRSC - Results from RNAi screens. • FBgn0039341 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039341 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5112-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039341 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43083 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43083 modMine - Data generated by the modENCODE project. • FBgn0039341
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5112 (Cermelli et al., 2006, Keleman et al., 2009.8.5, Cammarato et al., 2011, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 19 )
Research paper	Cermelli et al., 2006, Curr. Biol. 16(18): 1783--1795 The lipid-droplet proteome reveals that droplets are a protein-storage depot. [FBrf0192764]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Berkeley Drosophila Genome Project, 2006.4.26, BDGP TI submission. BDGP TI submission. [FBrf0188740] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]
Curated genome annotation	Ashburner, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126651]