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Gene Dmel\RpL27

General Information
Symbol	Dmel\RpL27	Species	D. melanogaster
Name	Ribosomal protein L27	Annotation symbol	CG4759
Feature type	protein_coding_gene	FlyBase ID	FBgn0039359
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	96E9-96E10	Sequence location	3R:21,509,345..21,510,773 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ribosomal protein L27 is referred to in FlyBase by the symbol Dmel\RpL27 (CG4759, FBgn0039359). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process: centrosome organization; mitotic spindle elongation; mitotic spindle organization; centrosome duplication. 2 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: KOW; Ribosomal protein L2 domain 2; Ribosomal protein L27e; Ribosomal protein L27e, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1632335_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of RpL27. Gene sequence location is 3R:21509345..21510773.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 96E9-96E10   Limits computationally determined from genome sequence between P{EP}EP3354 and P{PZ}l(3)rQ197rQ197
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RpL27 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Annotated transcripts do not represent all supported alternative splices within 5' UTR. Gene model reviewed during 5.44
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RpL27-RA FBtr0084932  NM_143160   537   135 RpL27-RB FBtr0331360  NM_001276037   603   135 RpL27-RC FBtr0331361  NM_001276038   544   135 RpL27-RD FBtr0331362  NM_001276039   987   135
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RpL27-PA   FBpp0084306   15.9   135   11.31     NP_651417   AAF56495 RpL27-PB   FBpp0303778   15.9   135   11.31     NP_001262966   AGB96346 RpL27-PC   FBpp0303779   15.9   135   11.31     NP_001262967   AGB96347 RpL27-PD   FBpp0303780   15.9   135   11.31     NP_001262968   AGB96348
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L27e, conserved site (IPR018262) Ribosomal protein L27e (IPR001141) KOW (IPR005824) Ribosomal protein L2 domain 2 (IPR014722)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA695962   AA801803   AA802614   AA803055   AA803848   AA804113   AA817121   AA817475   AE014297 AAF56495   AE014297 AGB96346   AE014297 AGB96347   AE014297 AGB96348   AI063593   AI108656   AI110207   AI113375   AI257211   AI258387   AI258745   AI260540   AI260545   AI260926   AI292738   AI293791   AI296658   AI389313   AI403580   AI511756   AI514755   AI515510   AI519369   AI532406   AY070827 AAL48449   AY232028   AY439348   BF491278   BG635628   BG635996   BG637194   BG637478   BG640199   BI141724   BI142147   BI162940   BI163331   BI164844   BI165620   BI169512   BI213298   BI215582   BI229337   BI229835   BI229884   BI230596   BI230750   BI232299   BI233275   BI236039   BI236422   BI236504   BI236584   BI237811   BI240153   BI241291   BI242373   BI242510   BI353125   BI353877   BI354884   BI356017   BI356746   BI358097   BI358604   BI361320   BI362106   BI366765   BI367130   BI368444   BI370215   BI370763   BI371285   BI372577   BI373112   BI374338   BI374725   BI375043   BI375098   BI375240   BI375549   BI376084   BI482136   BI482152   BI483568   BI483773   BI484340   BI484342   BI486639   BI564686   BI566039   BI566419   BI567163   BI567794   BI568133   BI569996   BI570009   BI571347   BI571907   BI572559   BI572768   BI574035   BI574036   BI575827   BI577266   BI578083   BI579231   BI579301   BI580959   BI580960   BI581540   BI582058   BI582074   BI582103   BI583769   BI586099   BI586811   BI587842   BI589038   BI591446   BI592407   BI593209   BI604476   BI604639   BI604990   BI605185   BI605274   BI605995   BI607631   BI607858   BI608937   BI609688   BI610107   BI610108   BI610487   BI611060   BI611797   BI612433   BI613397   BI613435   BI614108   BI616253   BI618758   BI619606   BI620692   BI620884   BI622057   BI622998   BI623872   BI624610   BI627419   BI627992   BI630147   BI630776   BI631088   BI631580   BI632928   BI633780   BI634936   BI636302   BI637065   BI639378   BI641349   BP540281   BP540282   BP541384   BP542407   BP543121   BP543122   BP543287   BP543288   BP543691   BP543692   BP544034   BP544035   BP544405   BP544406   BP545596   BP545597   BP545962   BP546071   BP546618   BP546781   BP547642   BP547662   BP548451   BP548588   BP549550   BP553006   BP553007   BP553212   BP553213   BP554073   BP554074   BP554630   BP554631   BP554707   BP554708   BP556136   BP556137   BP558926   BP558927   BP560371   BX048912   BX049417   CA804932   CA807547   CK657517   CK657596   CK660336   CK661881   CO152953   CO153130   CO153530   CO153728   CO153731   CO155058   CO155309   CO156536   CO156658   CO156679   CO157109   CO180013   CO181065   CO182550   CO183815   CO184272   CO191853   CO192065   CO192157   CO192663   CO193769   CO194111   CO195766   CO263429   CO263599   CO268670   CO278609   CO280836   CO286244   CO286263   CO286550   CO301117   CO304972   CO311658   CO312859   CO313854   CO314919   CO315604   CO330366   CO335390   CO336679   CO336790   CO337110   CO337607   CO337988   CO338095   CO338668   EC051325   EC202520   EC202769   EC213855   EC226157   EC227849   EC238371   EC238772   EC248792   EC249487   EC261083   EC262499   EC262732   EC263284   EC263303   EC264047   EC264507   EC264883   EC264967   EC265398   EC265448   EC265809   EC266135   EC267690   EC267883   EC267988   EL877251   EL877252   EL886204   EV575394   EV576129   EV577454   EV577654   EV577734   EV579307   EV579621   EV581000   EV581120   EV581455   EV583293   EV584919   EV585558   EV585690   EV585753   EV586414   EV594378   EV595432   EV597036   EV597460   EV599720   EV599755   EV600133   GH747978   GH748806   GH750460   GH752268   GH752550   GH754342   GH755866   GH755876   GH757732   GH759477   GH760868   GH771632   GH771792   GH772114   GH772257   GH773448   GH773590   GH774293   GH774955   GH775948   GH776219   GH776536   GH777149   GH777677   GH780481   GH781772   GH781952   GH785018   GH785459   GH785583   GH785741   GH785780   GH786374   GH786539   GH786728   GH787495   GH787824   GH788187   GH788405   GH788664   GH788712   GH789394   GH789744   GH790190   GH790279   GH790688   GH791480   GH792573   GH792989   GH793468   GH793605   GH794149   GH794152   GH794286   GH795813   GH798470   GH798518   GH799309   GH803320   GH803433   GH804243   GH804873   GH806624   GH807288   GH808240   GH809675   GH811313   GH811419   GH811869   GH813196   GH813796   GH814797   GH815004   GH815264   GH815647   GH816445   GH816847   GH817061   GH817132   GH817869   GH818385   GH818531   GH818823   GH821170   GH823866   GH826951   GH829274   GH830490   GH831295   GH831521   GH832462   GH832794   GH832831   GH832988   GH833253   GH833471   GH833577   GH833714   GH835006   GH835818   GH836143   GH836562   GH837256   GH838158   GH838685   GH839623   GH839723   GH840162   GH840309   GH840317   GH841186   GH841513   GH842080   GH843321   GH845393   GH846576   GH847738   GH848016   GH848301   GH848400   GH849157   GH852258   GH852513   GH852804   GH853103   GH853510   GH854504   GH854792   GH854806   GH854875   GH855002   GH855329   GH856137   GH856599   GH856978   GH858030   GH858494   GH858673   GH858849   GH859447   GH859530   GH859817   GH859894   GH861241   GH861303   GH861638   GH864249   GH864549   GH865449   GH868298   GH868816   GH869990   GH870083   GH872199   GH872439   GH872519   GH873162   GH874894   GH875077   GH875845   GH877295   GH877682   GH878246   GH879425   GH879458   GH880076   GH880385   GH880738   GH881534   GH881813   GH882207   GH883270   GH883337   GH883351   GH884114   GH885242   GH885255   GH886256   GH886614   GH886954   GH887164   GH887328   GH887582   GH887827   GH887836   GH887875   GH888784   GH889930   GH890480   GH891770   GH892203   GH892506   GH892782   GH893605   GH893667   GH894229   GH894493   GH894494   GH894731   GH894992   GH894995   GH895058   GH895407   GH895818   GH896725   GH897823   GH898506   GH898554   GH898818   GH899201   GH899345   GH899415   GH899453   GH900004   GH900204   GH900516   GH901082   GH901359   GH901984   GH902429   GH903154   GH903211   GH905018   GH905820   GH906155   GH906474   GH906485   GH906523   GH908305   GH908629   GH910033   GH910841   GH911146   GH911321   GH912698   GH916215   GH917133   GH917314   GH918946   GH919013   GH919845   GH921425   GH921608   GH922894   GH924966   GH925246   GH925449   GH925880   GH926262   GH926594   GH927172   GH927617   GH928357   GH928392   GH928573   GH929131   GH929484   GH929702   GH930363   GH930736   GH930765   GH931288   GH931438   GH932593   GH932632   GH932710   GH933107   GH934045   GH934401   GH935509   GH936054   GH936134   GH939161
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VBN5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2868.75 Larval Midgut    5009.2 Larval Hindgut    4814.3 Larval Malpighian Tubules    3696.9 Larval Fat Body    7341.7 Larval Salivary Gland    8346.6 Larval Trachea    5874.9 Larval Carcass    4989.6 Adult Head    4516.6 Adult Eye    6434.7 Adult Brain    2620.6 Adult Thoracic-Abdominal Ganglion    3559.2 Adult Crop    5580.5 Adult Midgut    5226.5 Adult Hindgut    4775.5 Adult Malpighian Tubules    1168.1 Adult Fat Body    6578.9 Adult Salivary Gland    11151 Adult Heart    6731.55 Adult VirginFemale Spermatheca    5098.9 Adult InseminatedFemale Spermatheca    5294.5 Adult Ovary    3453.5 Adult Testis    409.4 Adult Male Accessory Gland    7984.5 Adult Carcass    5283.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2868.75) Larval Midgut  (5009.2) Larval Hindgut  (4814.3) Larval Malpighian Tubules  (3696.9) Larval Fat Body  (7341.7) Larval Salivary Gland  (8346.6) Larval Trachea  (5874.9) Larval Carcass  (4989.6) Adult Head  (4516.6) Adult Eye  (6434.7) Adult Brain  (2620.6) Adult Thoracic-Abdominal Ganglion  (3559.2) Adult Crop  (5580.5) Adult Midgut  (5226.5) Adult Hindgut  (4775.5) Adult Malpighian Tubules  (1168.1) Adult Fat Body  (6578.9) Adult Salivary Gland  (11151) Adult Heart  (6731.55) Adult VirginFemale Spermatheca  (5098.9) Adult InseminatedFemale Spermatheca  (5294.5) Adult Ovary  (3453.5) Adult Testis    409.4 Adult Male Accessory Gland  (7984.5) Adult Carcass  (5283.4) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2868.75) Larval Midgut  (5009.2) Larval Hindgut  (4814.3) Larval Malpighian Tubules  (3696.9) Larval Fat Body  (7341.7) Larval Salivary Gland  (8346.6) Larval Trachea  (5874.9) Larval Carcass  (4989.6) Adult Head  (4516.6) Adult Eye  (6434.7) Adult Brain  (2620.6) Adult Thoracic-Abdominal Ganglion  (3559.2) Adult Crop  (5580.5) Adult Midgut  (5226.5) Adult Hindgut  (4775.5) Adult Malpighian Tubules  (1168.1) Adult Fat Body  (6578.9) Adult Salivary Gland  (11151) Adult Heart  (6731.55) Adult VirginFemale Spermatheca  (5098.9) Adult InseminatedFemale Spermatheca  (5294.5) Adult Ovary  (3453.5) Adult Testis    409.4 Adult Male Accessory Gland  (7984.5) Adult Carcass  (5283.4) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2868.75 Larval Midgut    5009.2 Larval Hindgut    4814.3 Larval Malpighian Tubules    3696.9 Larval Fat Body    7341.7 Larval Salivary Gland    8346.6 Larval Trachea    5874.9 Larval Carcass    4989.6 Adult Head    4516.6 Adult Eye    6434.7 Adult Brain    2620.6 Adult Thoracic-Abdominal Ganglion    3559.2 Adult Crop    5580.5 Adult Midgut    5226.5 Adult Hindgut    4775.5 Adult Malpighian Tubules    1168.1 Adult Fat Body    6578.9 Adult Salivary Gland    11151 Adult Heart    6731.55 Adult VirginFemale Spermatheca    5098.9 Adult InseminatedFemale Spermatheca    5294.5 Adult Ovary    3453.5 Adult Testis    409.4 Adult Male Accessory Gland    7984.5 Adult Carcass    5283.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2868.75 Larval Midgut    5009.2 Larval Hindgut    4814.3 Larval Malpighian Tubules    3696.9 Larval Fat Body    7341.7 Larval Salivary Gland    8346.6 Larval Trachea    5874.9 Larval Carcass    4989.6 Adult Head    4516.6 Adult Eye    6434.7 Adult Brain    2620.6 Adult Thoracic-Abdominal Ganglion    3559.2 Adult Crop    5580.5 Adult Midgut    5226.5 Adult Hindgut    4775.5 Adult Malpighian Tubules    1168.1 Adult Fat Body    6578.9 Adult Salivary Gland    11151 Adult Heart    6731.55 Adult VirginFemale Spermatheca    5098.9 Adult InseminatedFemale Spermatheca    5294.5 Adult Ovary    3453.5 Adult Testis    409.4 Adult Male Accessory Gland    7984.5 Adult Carcass    5283.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2868.75) Larval Midgut  (5009.2) Larval Hindgut  (4814.3) Larval Malpighian Tubules  (3696.9) Larval Fat Body  (7341.7) Larval Salivary Gland  (8346.6) Larval Trachea  (5874.9) Larval Carcass  (4989.6) Adult Head  (4516.6) Adult Eye  (6434.7) Adult Brain  (2620.6) Adult Thoracic-Abdominal Ganglion  (3559.2) Adult Crop  (5580.5) Adult Midgut  (5226.5) Adult Hindgut  (4775.5) Adult Malpighian Tubules  (1168.1) Adult Fat Body  (6578.9) Adult Salivary Gland  (11151) Adult Heart  (6731.55) Adult VirginFemale Spermatheca  (5098.9) Adult InseminatedFemale Spermatheca  (5294.5) Adult Ovary  (3453.5) Adult Testis    409.4 Adult Male Accessory Gland  (7984.5) Adult Carcass  (5283.4) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2868.75) Larval Midgut  (5009.2) Larval Hindgut  (4814.3) Larval Malpighian Tubules  (3696.9) Larval Fat Body  (7341.7) Larval Salivary Gland  (8346.6) Larval Trachea  (5874.9) Larval Carcass  (4989.6) Adult Head  (4516.6) Adult Eye  (6434.7) Adult Brain  (2620.6) Adult Thoracic-Abdominal Ganglion  (3559.2) Adult Crop  (5580.5) Adult Midgut  (5226.5) Adult Hindgut  (4775.5) Adult Malpighian Tubules  1168.1 Adult Fat Body  (6578.9) Adult Salivary Gland  (11151) Adult Heart  (6731.55) Adult VirginFemale Spermatheca  (5098.9) Adult InseminatedFemale Spermatheca  (5294.5) Adult Ovary  (3453.5) Adult Testis    409.4 Adult Male Accessory Gland  (7984.5) Adult Carcass  (5283.4) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2868.75 Larval Midgut    5009.2 Larval Hindgut    4814.3 Larval Malpighian Tubules    3696.9 Larval Fat Body    7341.7 Larval Salivary Gland    8346.6 Larval Trachea    5874.9 Larval Carcass    4989.6 Adult Head    4516.6 Adult Eye    6434.7 Adult Brain    2620.6 Adult Thoracic-Abdominal Ganglion    3559.2 Adult Crop    5580.5 Adult Midgut    5226.5 Adult Hindgut    4775.5 Adult Malpighian Tubules    1168.1 Adult Fat Body    6578.9 Adult Salivary Gland    11151 Adult Heart    6731.55 Adult VirginFemale Spermatheca    5098.9 Adult InseminatedFemale Spermatheca    5294.5 Adult Ovary    3453.5 Adult Testis    409.4 Adult Male Accessory Gland    7984.5 Adult Carcass    5283.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    4516.6   NA  Eye    6434.7   NA  Brain    2620.6   2868.75  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    3559.2   NA  Crop    5580.5   5009.2  Midgut    5226.5   4814.3  Hindgut    4775.5   3696.9  Malpighian Tubules    1168.1   7341.7  Fat Body    6578.9   8346.6  Salivary Gland    11151   NA  Heart    6731.55   5874.9  Trachea    NA   NA  VirginFemale Spermatheca    5098.9   NA  InseminatedFemale Spermatheca    5294.5   NA  Ovary    3453.5   NA  Testis    409.4   NA  Male Accessory Gland    7984.5   4989.6  Carcass    5283.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1903 central nervous system, larvae L3    1296 central nervous system, pupae P8    486 head, virgin 1-day female    755 head, virgin 4-day female    1249 head, virgin 20-day female    1213 head, mated 1-day female    747 head, mated 4-day female    819 head, mated 20-day female    1043 head, mated 1-day male    691 head, mated 4-day male    563 head, mated 20-day male    836 salivary gland, larvae L3 wandering    897 salivary gland, white prepupae    2099 digestive system, larvae L3 wandering    1083 digestive system, 1-day adult    784 digestive system, 4-day adult    784 digestive system, 20-day adult    864 fat body, larvae L3 wandering    695 fat body, white prepupae    639 fat body, pupae P8    1415 carcass, larvae L3 wandering    1507 carcass, 1-day adult    725 carcass, 4-day adult    787 carcass, 20-day adult    1229 ovary, virgin 4-day female    1362 ovary, mated 4-day female    1192 testis, mated 4-day male    479 accessory gland, mated 4-day male    1100 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1903) central nervous system, larvae L3  (1296) central nervous system, pupae P8  (486) head, virgin 1-day female  (755) head, virgin 4-day female  (1249) head, virgin 20-day female  (1213) head, mated 1-day female  (747) head, mated 4-day female  (819) head, mated 20-day female  (1043) head, mated 1-day male  (691) head, mated 4-day male  (563) head, mated 20-day male  (836) salivary gland, larvae L3 wandering  (897) salivary gland, white prepupae  (2099) digestive system, larvae L3 wandering  (1083) digestive system, 1-day adult  (784) digestive system, 4-day adult  (784) digestive system, 20-day adult  (864) fat body, larvae L3 wandering  (695) fat body, white prepupae  (639) fat body, pupae P8  (1415) carcass, larvae L3 wandering  (1507) carcass, 1-day adult  (725) carcass, 4-day adult  (787) carcass, 20-day adult  (1229) ovary, virgin 4-day female  (1362) ovary, mated 4-day female  (1192) testis, mated 4-day male  (479) accessory gland, mated 4-day male  (1100) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1903) central nervous system, larvae L3  (1296) central nervous system, pupae P8  (486) head, virgin 1-day female  (755) head, virgin 4-day female  (1249) head, virgin 20-day female  (1213) head, mated 1-day female  (747) head, mated 4-day female  (819) head, mated 20-day female  (1043) head, mated 1-day male  (691) head, mated 4-day male  (563) head, mated 20-day male  (836) salivary gland, larvae L3 wandering  (897) salivary gland, white prepupae  (2099) digestive system, larvae L3 wandering  (1083) digestive system, 1-day adult  (784) digestive system, 4-day adult  (784) digestive system, 20-day adult  (864) fat body, larvae L3 wandering  (695) fat body, white prepupae  (639) fat body, pupae P8  (1415) carcass, larvae L3 wandering  (1507) carcass, 1-day adult  (725) carcass, 4-day adult  (787) carcass, 20-day adult  (1229) ovary, virgin 4-day female  (1362) ovary, mated 4-day female  (1192) testis, mated 4-day male  (479) accessory gland, mated 4-day male  (1100) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1903 central nervous system, larvae L3    1296 central nervous system, pupae P8    486 head, virgin 1-day female    755 head, virgin 4-day female    1249 head, virgin 20-day female    1213 head, mated 1-day female    747 head, mated 4-day female    819 head, mated 20-day female    1043 head, mated 1-day male    691 head, mated 4-day male    563 head, mated 20-day male    836 salivary gland, larvae L3 wandering    897 salivary gland, white prepupae    2099 digestive system, larvae L3 wandering    1083 digestive system, 1-day adult    784 digestive system, 4-day adult    784 digestive system, 20-day adult    864 fat body, larvae L3 wandering    695 fat body, white prepupae    639 fat body, pupae P8    1415 carcass, larvae L3 wandering    1507 carcass, 1-day adult    725 carcass, 4-day adult    787 carcass, 20-day adult    1229 ovary, virgin 4-day female    1362 ovary, mated 4-day female    1192 testis, mated 4-day male    479 accessory gland, mated 4-day male    1100 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1903 central nervous system, larvae L3    1296 central nervous system, pupae P8    486 head, virgin 1-day female    755 head, virgin 4-day female    1249 head, virgin 20-day female    1213 head, mated 1-day female    747 head, mated 4-day female    819 head, mated 20-day female    1043 head, mated 1-day male    691 head, mated 4-day male    563 head, mated 20-day male    836 salivary gland, larvae L3 wandering    897 salivary gland, white prepupae    2099 digestive system, larvae L3 wandering    1083 digestive system, 1-day adult    784 digestive system, 4-day adult    784 digestive system, 20-day adult    864 fat body, larvae L3 wandering    695 fat body, white prepupae    639 fat body, pupae P8    1415 carcass, larvae L3 wandering    1507 carcass, 1-day adult    725 carcass, 4-day adult    787 carcass, 20-day adult    1229 ovary, virgin 4-day female    1362 ovary, mated 4-day female    1192 testis, mated 4-day male    479 accessory gland, mated 4-day male    1100 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1903) central nervous system, larvae L3  (1296) central nervous system, pupae P8  (486) head, virgin 1-day female  (755) head, virgin 4-day female  (1249) head, virgin 20-day female  (1213) head, mated 1-day female  (747) head, mated 4-day female  (819) head, mated 20-day female  (1043) head, mated 1-day male  (691) head, mated 4-day male  (563) head, mated 20-day male  (836) salivary gland, larvae L3 wandering  (897) salivary gland, white prepupae  (2099) digestive system, larvae L3 wandering  (1083) digestive system, 1-day adult  (784) digestive system, 4-day adult  (784) digestive system, 20-day adult  (864) fat body, larvae L3 wandering  (695) fat body, white prepupae  (639) fat body, pupae P8  (1415) carcass, larvae L3 wandering  (1507) carcass, 1-day adult  (725) carcass, 4-day adult  (787) carcass, 20-day adult  (1229) ovary, virgin 4-day female  (1362) ovary, mated 4-day female  (1192) testis, mated 4-day male  (479) accessory gland, mated 4-day male  (1100) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1903) central nervous system, larvae L3  (1296) central nervous system, pupae P8  (486) head, virgin 1-day female  (755) head, virgin 4-day female  (1249) head, virgin 20-day female  (1213) head, mated 1-day female  (747) head, mated 4-day female  (819) head, mated 20-day female  (1043) head, mated 1-day male  (691) head, mated 4-day male  (563) head, mated 20-day male  (836) salivary gland, larvae L3 wandering  (897) salivary gland, white prepupae  (2099) digestive system, larvae L3 wandering  (1083) digestive system, 1-day adult  (784) digestive system, 4-day adult  (784) digestive system, 20-day adult  (864) fat body, larvae L3 wandering  (695) fat body, white prepupae  (639) fat body, pupae P8  (1415) carcass, larvae L3 wandering  (1507) carcass, 1-day adult  (725) carcass, 4-day adult  (787) carcass, 20-day adult  (1229) ovary, virgin 4-day female  (1362) ovary, mated 4-day female  (1192) testis, mated 4-day male  (479) accessory gland, mated 4-day male  (1100) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1903 central nervous system, larvae L3    1296 central nervous system, pupae P8    486 head, virgin 1-day female    755 head, virgin 4-day female    1249 head, virgin 20-day female    1213 head, mated 1-day female    747 head, mated 4-day female    819 head, mated 20-day female    1043 head, mated 1-day male    691 head, mated 4-day male    563 head, mated 20-day male    836 salivary gland, larvae L3 wandering    897 salivary gland, white prepupae    2099 digestive system, larvae L3 wandering    1083 digestive system, 1-day adult    784 digestive system, 4-day adult    784 digestive system, 20-day adult    864 fat body, larvae L3 wandering    695 fat body, white prepupae    639 fat body, pupae P8    1415 carcass, larvae L3 wandering    1507 carcass, 1-day adult    725 carcass, 4-day adult    787 carcass, 20-day adult    1229 ovary, virgin 4-day female    1362 ovary, mated 4-day female    1192 testis, mated 4-day male    479 accessory gland, mated 4-day male    1100 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1104 embryo 02-04hr    1764 embryo 04-06hr    1923 embryo 06-08hr    1863 embryo 08-10hr    2108 embryo 10-12hr    1959 embryo 12-14hr    1656 embryo 14-16hr    1486 embryo 16-18hr    1484 embryo 18-20hr    1702 embryo 20-22hr    1891 embryo 22-24hr    1887 larva L1    2060 larva L2    2078 larva L3 12hr old    1589 larva L3 puffstage 1-2    1302 larva L3 puffstage 3-6    1167 larva L3 puffstage 7-9    1218 white prepupae new    1104 white prepupae 12hr    942 white prepupae 24hr    918 pupae 2d postWPP    868 pupae 3d postWPP    747 pupae 4d postWPP    621 adult male 01day    579 adult male 05day    580 adult male 30day    589 adult female 01day    1174 adult female 05day    1448 adult female 30day    1417 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1104) embryo 02-04hr  (1764) embryo 04-06hr  (1923) embryo 06-08hr  (1863) embryo 08-10hr  (2108) embryo 10-12hr  (1959) embryo 12-14hr  (1656) embryo 14-16hr  (1486) embryo 16-18hr  (1484) embryo 18-20hr  (1702) embryo 20-22hr  (1891) embryo 22-24hr  (1887) larva L1  (2060) larva L2  (2078) larva L3 12hr old  (1589) larva L3 puffstage 1-2  (1302) larva L3 puffstage 3-6  (1167) larva L3 puffstage 7-9  (1218) white prepupae new  (1104) white prepupae 12hr  (942) white prepupae 24hr  (918) pupae 2d postWPP  (868) pupae 3d postWPP  (747) pupae 4d postWPP  (621) adult male 01day  (579) adult male 05day  (580) adult male 30day  (589) adult female 01day  (1174) adult female 05day  (1448) adult female 30day  (1417) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1104) embryo 02-04hr  (1764) embryo 04-06hr  (1923) embryo 06-08hr  (1863) embryo 08-10hr  (2108) embryo 10-12hr  (1959) embryo 12-14hr  (1656) embryo 14-16hr  (1486) embryo 16-18hr  (1484) embryo 18-20hr  (1702) embryo 20-22hr  (1891) embryo 22-24hr  (1887) larva L1  (2060) larva L2  (2078) larva L3 12hr old  (1589) larva L3 puffstage 1-2  (1302) larva L3 puffstage 3-6  (1167) larva L3 puffstage 7-9  (1218) white prepupae new  (1104) white prepupae 12hr  (942) white prepupae 24hr  (918) pupae 2d postWPP  (868) pupae 3d postWPP  (747) pupae 4d postWPP  (621) adult male 01day  (579) adult male 05day  (580) adult male 30day  (589) adult female 01day  (1174) adult female 05day  (1448) adult female 30day  (1417) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1104 embryo 02-04hr    1764 embryo 04-06hr    1923 embryo 06-08hr    1863 embryo 08-10hr    2108 embryo 10-12hr    1959 embryo 12-14hr    1656 embryo 14-16hr    1486 embryo 16-18hr    1484 embryo 18-20hr    1702 embryo 20-22hr    1891 embryo 22-24hr    1887 larva L1    2060 larva L2    2078 larva L3 12hr old    1589 larva L3 puffstage 1-2    1302 larva L3 puffstage 3-6    1167 larva L3 puffstage 7-9    1218 white prepupae new    1104 white prepupae 12hr    942 white prepupae 24hr    918 pupae 2d postWPP    868 pupae 3d postWPP    747 pupae 4d postWPP    621 adult male 01day    579 adult male 05day    580 adult male 30day    589 adult female 01day    1174 adult female 05day    1448 adult female 30day    1417 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1104 embryo 02-04hr    1764 embryo 04-06hr    1923 embryo 06-08hr    1863 embryo 08-10hr    2108 embryo 10-12hr    1959 embryo 12-14hr    1656 embryo 14-16hr    1486 embryo 16-18hr    1484 embryo 18-20hr    1702 embryo 20-22hr    1891 embryo 22-24hr    1887 larva L1    2060 larva L2    2078 larva L3 12hr old    1589 larva L3 puffstage 1-2    1302 larva L3 puffstage 3-6    1167 larva L3 puffstage 7-9    1218 white prepupae new    1104 white prepupae 12hr    942 white prepupae 24hr    918 pupae 2d postWPP    868 pupae 3d postWPP    747 pupae 4d postWPP    621 adult male 01day    579 adult male 05day    580 adult male 30day    589 adult female 01day    1174 adult female 05day    1448 adult female 30day    1417 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1104) embryo 02-04hr  (1764) embryo 04-06hr  (1923) embryo 06-08hr  (1863) embryo 08-10hr  (2108) embryo 10-12hr  (1959) embryo 12-14hr  (1656) embryo 14-16hr  (1486) embryo 16-18hr  (1484) embryo 18-20hr  (1702) embryo 20-22hr  (1891) embryo 22-24hr  (1887) larva L1  (2060) larva L2  (2078) larva L3 12hr old  (1589) larva L3 puffstage 1-2  (1302) larva L3 puffstage 3-6  (1167) larva L3 puffstage 7-9  (1218) white prepupae new  (1104) white prepupae 12hr  (942) white prepupae 24hr  (918) pupae 2d postWPP  (868) pupae 3d postWPP  (747) pupae 4d postWPP  (621) adult male 01day  (579) adult male 05day  (580) adult male 30day  (589) adult female 01day  (1174) adult female 05day  (1448) adult female 30day  (1417) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1104) embryo 02-04hr  (1764) embryo 04-06hr  (1923) embryo 06-08hr  (1863) embryo 08-10hr  (2108) embryo 10-12hr  (1959) embryo 12-14hr  (1656) embryo 14-16hr  (1486) embryo 16-18hr  (1484) embryo 18-20hr  (1702) embryo 20-22hr  (1891) embryo 22-24hr  (1887) larva L1  (2060) larva L2  (2078) larva L3 12hr old  (1589) larva L3 puffstage 1-2  (1302) larva L3 puffstage 3-6  (1167) larva L3 puffstage 7-9  (1218) white prepupae new  (1104) white prepupae 12hr  (942) white prepupae 24hr  (918) pupae 2d postWPP  (868) pupae 3d postWPP  (747) pupae 4d postWPP  (621) adult male 01day  (579) adult male 05day  (580) adult male 30day  (589) adult female 01day  (1174) adult female 05day  (1448) adult female 30day  (1417) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1104 embryo 02-04hr    1764 embryo 04-06hr    1923 embryo 06-08hr    1863 embryo 08-10hr    2108 embryo 10-12hr    1959 embryo 12-14hr    1656 embryo 14-16hr    1486 embryo 16-18hr    1484 embryo 18-20hr    1702 embryo 20-22hr    1891 embryo 22-24hr    1887 larva L1    2060 larva L2    2078 larva L3 12hr old    1589 larva L3 puffstage 1-2    1302 larva L3 puffstage 3-6    1167 larva L3 puffstage 7-9    1218 white prepupae new    1104 white prepupae 12hr    942 white prepupae 24hr    918 pupae 2d postWPP    868 pupae 3d postWPP    747 pupae 4d postWPP    621 adult male 01day    579 adult male 05day    580 adult male 30day    589 adult female 01day    1174 adult female 05day    1448 adult female 30day    1417 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2072 Schneider line 2 Sg4    1042 embryonic 1182-4H    2858 embryonic GM2    1137 embryonic Kc167    818 embryonic S1    1948 embryonic S3    1504 leg disc CME L1    2284 wing disc CME-W2    1425 wing disc ML-DmD8    2211 wing disc ML-DmD9    2394 wing disc ML-DmD16-c3    2068 wing disc ML-DmD21    2578 wing disc ML-DmD32    1791 haltere disc ML-DmD17-c3    1104 eye-antennal disc ML-DmD11    3030 antennal disc ML-DmD20-c5    2281 mixed discs ML-DmD4-c1    1936 CNS ML-DmBG1-c1    2806 CNS ML-DmBG2-c2    1435 tumorous blood cells mbn2    1519 ovary fGS/OSS    1767 ovary OSC    1526 ovary OSS    717 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (2072) Schneider line 2 Sg4  (1042) embryonic 1182-4H  (2858) embryonic GM2  (1137) embryonic Kc167  (818) embryonic S1  (1948) embryonic S3  (1504) leg disc CME L1  (2284) wing disc CME-W2  (1425) wing disc ML-DmD8  (2211) wing disc ML-DmD9  (2394) wing disc ML-DmD16-c3  (2068) wing disc ML-DmD21  (2578) wing disc ML-DmD32  (1791) haltere disc ML-DmD17-c3  (1104) eye-antennal disc ML-DmD11  (3030) antennal disc ML-DmD20-c5  (2281) mixed discs ML-DmD4-c1  (1936) CNS ML-DmBG1-c1  (2806) CNS ML-DmBG2-c2  (1435) tumorous blood cells mbn2  (1519) ovary fGS/OSS  (1767) ovary OSC  (1526) ovary OSS  (717) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (2072) Schneider line 2 Sg4  (1042) embryonic 1182-4H  (2858) embryonic GM2  (1137) embryonic Kc167  (818) embryonic S1  (1948) embryonic S3  (1504) leg disc CME L1  (2284) wing disc CME-W2  (1425) wing disc ML-DmD8  (2211) wing disc ML-DmD9  (2394) wing disc ML-DmD16-c3  (2068) wing disc ML-DmD21  (2578) wing disc ML-DmD32  (1791) haltere disc ML-DmD17-c3  (1104) eye-antennal disc ML-DmD11  (3030) antennal disc ML-DmD20-c5  (2281) mixed discs ML-DmD4-c1  (1936) CNS ML-DmBG1-c1  (2806) CNS ML-DmBG2-c2  (1435) tumorous blood cells mbn2  (1519) ovary fGS/OSS  (1767) ovary OSC  (1526) ovary OSS  (717) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2072 Schneider line 2 Sg4    1042 embryonic 1182-4H    2858 embryonic GM2    1137 embryonic Kc167    818 embryonic S1    1948 embryonic S3    1504 leg disc CME L1    2284 wing disc CME-W2    1425 wing disc ML-DmD8    2211 wing disc ML-DmD9    2394 wing disc ML-DmD16-c3    2068 wing disc ML-DmD21    2578 wing disc ML-DmD32    1791 haltere disc ML-DmD17-c3    1104 eye-antennal disc ML-DmD11    3030 antennal disc ML-DmD20-c5    2281 mixed discs ML-DmD4-c1    1936 CNS ML-DmBG1-c1    2806 CNS ML-DmBG2-c2    1435 tumorous blood cells mbn2    1519 ovary fGS/OSS    1767 ovary OSC    1526 ovary OSS    717 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2072 Schneider line 2 Sg4    1042 embryonic 1182-4H    2858 embryonic GM2    1137 embryonic Kc167    818 embryonic S1    1948 embryonic S3    1504 leg disc CME L1    2284 wing disc CME-W2    1425 wing disc ML-DmD8    2211 wing disc ML-DmD9    2394 wing disc ML-DmD16-c3    2068 wing disc ML-DmD21    2578 wing disc ML-DmD32    1791 haltere disc ML-DmD17-c3    1104 eye-antennal disc ML-DmD11    3030 antennal disc ML-DmD20-c5    2281 mixed discs ML-DmD4-c1    1936 CNS ML-DmBG1-c1    2806 CNS ML-DmBG2-c2    1435 tumorous blood cells mbn2    1519 ovary fGS/OSS    1767 ovary OSC    1526 ovary OSS    717 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (2072) Schneider line 2 Sg4  (1042) embryonic 1182-4H  (2858) embryonic GM2  (1137) embryonic Kc167  (818) embryonic S1  (1948) embryonic S3  (1504) leg disc CME L1  (2284) wing disc CME-W2  (1425) wing disc ML-DmD8  (2211) wing disc ML-DmD9  (2394) wing disc ML-DmD16-c3  (2068) wing disc ML-DmD21  (2578) wing disc ML-DmD32  (1791) haltere disc ML-DmD17-c3  (1104) eye-antennal disc ML-DmD11  (3030) antennal disc ML-DmD20-c5  (2281) mixed discs ML-DmD4-c1  (1936) CNS ML-DmBG1-c1  (2806) CNS ML-DmBG2-c2  (1435) tumorous blood cells mbn2  (1519) ovary fGS/OSS  (1767) ovary OSC  (1526) ovary OSS  (717) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (2072) Schneider line 2 Sg4  (1042) embryonic 1182-4H  (2858) embryonic GM2  (1137) embryonic Kc167  (818) embryonic S1  (1948) embryonic S3  (1504) leg disc CME L1  (2284) wing disc CME-W2  (1425) wing disc ML-DmD8  (2211) wing disc ML-DmD9  (2394) wing disc ML-DmD16-c3  (2068) wing disc ML-DmD21  (2578) wing disc ML-DmD32  (1791) haltere disc ML-DmD17-c3  (1104) eye-antennal disc ML-DmD11  (3030) antennal disc ML-DmD20-c5  (2281) mixed discs ML-DmD4-c1  (1936) CNS ML-DmBG1-c1  (2806) CNS ML-DmBG2-c2  (1435) tumorous blood cells mbn2  (1519) ovary fGS/OSS  (1767) ovary OSC  (1526) ovary OSS  (717) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2072 Schneider line 2 Sg4    1042 embryonic 1182-4H    2858 embryonic GM2    1137 embryonic Kc167    818 embryonic S1    1948 embryonic S3    1504 leg disc CME L1    2284 wing disc CME-W2    1425 wing disc ML-DmD8    2211 wing disc ML-DmD9    2394 wing disc ML-DmD16-c3    2068 wing disc ML-DmD21    2578 wing disc ML-DmD32    1791 haltere disc ML-DmD17-c3    1104 eye-antennal disc ML-DmD11    3030 antennal disc ML-DmD20-c5    2281 mixed discs ML-DmD4-c1    1936 CNS ML-DmBG1-c1    2806 CNS ML-DmBG2-c2    1435 tumorous blood cells mbn2    1519 ovary fGS/OSS    1767 ovary OSC    1526 ovary OSS    717 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1017 cold shock, 4-day adult    857 heat shock, 4-day adult    1191 Cadmium 50 mM 6 hrs, larvae L3    1160 Cadmium 50 mM 12 hrs, larvae L3    1270 Cadmium 50 mM 48 hrs, 4-day adult    989 Cadmium 100 mM 48 hrs, 4-day adult    1115 Copper 0.5 mM 12 hrs, larvae L3    1188 Copper 15 mM 48 hrs, 4-day adult    333 Zinc 5 mM 12 hrs, larvae L3    1033 Zinc 4.5 mM 48 hrs, 4-day adult    551 Ethanol 2.5% 3 hrs, larvae L3    1187 Ethanol 5% 3 hrs, larvae L3    1193 Ethanol 10% 3 hrs, larvae L3    1250 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1304 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1254 Caffeine 25 mg/ml 48 hrs, 4-day adult    692 Paraquat 5 mM 48 hrs, 4-day adult    1114 Paraquat 10 mM 48 hrs, 4-day adult    1180 Rotenone 2 μg 12 hrs, larvae L3    1378 Rotenone 8 μg 12 hrs, larvae L3    1811 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (1017) cold shock, 4-day adult  (857) heat shock, 4-day adult  (1191) Cadmium 50 mM 6 hrs, larvae L3  (1160) Cadmium 50 mM 12 hrs, larvae L3  (1270) Cadmium 50 mM 48 hrs, 4-day adult  (989) Cadmium 100 mM 48 hrs, 4-day adult  (1115) Copper 0.5 mM 12 hrs, larvae L3  (1188) Copper 15 mM 48 hrs, 4-day adult  (333) Zinc 5 mM 12 hrs, larvae L3  (1033) Zinc 4.5 mM 48 hrs, 4-day adult  (551) Ethanol 2.5% 3 hrs, larvae L3  (1187) Ethanol 5% 3 hrs, larvae L3  (1193) Ethanol 10% 3 hrs, larvae L3  (1250) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1304) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (1254) Caffeine 25 mg/ml 48 hrs, 4-day adult  (692) Paraquat 5 mM 48 hrs, 4-day adult  (1114) Paraquat 10 mM 48 hrs, 4-day adult  (1180) Rotenone 2 μg 12 hrs, larvae L3  (1378) Rotenone 8 μg 12 hrs, larvae L3  (1811) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (1017) cold shock, 4-day adult  (857) heat shock, 4-day adult  (1191) Cadmium 50 mM 6 hrs, larvae L3  (1160) Cadmium 50 mM 12 hrs, larvae L3  (1270) Cadmium 50 mM 48 hrs, 4-day adult  (989) Cadmium 100 mM 48 hrs, 4-day adult  (1115) Copper 0.5 mM 12 hrs, larvae L3  (1188) Copper 15 mM 48 hrs, 4-day adult  (333) Zinc 5 mM 12 hrs, larvae L3  (1033) Zinc 4.5 mM 48 hrs, 4-day adult  (551) Ethanol 2.5% 3 hrs, larvae L3  (1187) Ethanol 5% 3 hrs, larvae L3  (1193) Ethanol 10% 3 hrs, larvae L3  (1250) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1304) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (1254) Caffeine 25 mg/ml 48 hrs, 4-day adult  (692) Paraquat 5 mM 48 hrs, 4-day adult  (1114) Paraquat 10 mM 48 hrs, 4-day adult  (1180) Rotenone 2 μg 12 hrs, larvae L3  (1378) Rotenone 8 μg 12 hrs, larvae L3  (1811) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1017 cold shock, 4-day adult    857 heat shock, 4-day adult    1191 Cadmium 50 mM 6 hrs, larvae L3    1160 Cadmium 50 mM 12 hrs, larvae L3    1270 Cadmium 50 mM 48 hrs, 4-day adult    989 Cadmium 100 mM 48 hrs, 4-day adult    1115 Copper 0.5 mM 12 hrs, larvae L3    1188 Copper 15 mM 48 hrs, 4-day adult    333 Zinc 5 mM 12 hrs, larvae L3    1033 Zinc 4.5 mM 48 hrs, 4-day adult    551 Ethanol 2.5% 3 hrs, larvae L3    1187 Ethanol 5% 3 hrs, larvae L3    1193 Ethanol 10% 3 hrs, larvae L3    1250 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1304 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1254 Caffeine 25 mg/ml 48 hrs, 4-day adult    692 Paraquat 5 mM 48 hrs, 4-day adult    1114 Paraquat 10 mM 48 hrs, 4-day adult    1180 Rotenone 2 μg 12 hrs, larvae L3    1378 Rotenone 8 μg 12 hrs, larvae L3    1811 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1017 cold shock, 4-day adult    857 heat shock, 4-day adult    1191 Cadmium 50 mM 6 hrs, larvae L3    1160 Cadmium 50 mM 12 hrs, larvae L3    1270 Cadmium 50 mM 48 hrs, 4-day adult    989 Cadmium 100 mM 48 hrs, 4-day adult    1115 Copper 0.5 mM 12 hrs, larvae L3    1188 Copper 15 mM 48 hrs, 4-day adult    333 Zinc 5 mM 12 hrs, larvae L3    1033 Zinc 4.5 mM 48 hrs, 4-day adult    551 Ethanol 2.5% 3 hrs, larvae L3    1187 Ethanol 5% 3 hrs, larvae L3    1193 Ethanol 10% 3 hrs, larvae L3    1250 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1304 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1254 Caffeine 25 mg/ml 48 hrs, 4-day adult    692 Paraquat 5 mM 48 hrs, 4-day adult    1114 Paraquat 10 mM 48 hrs, 4-day adult    1180 Rotenone 2 μg 12 hrs, larvae L3    1378 Rotenone 8 μg 12 hrs, larvae L3    1811 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (1017) cold shock, 4-day adult  (857) heat shock, 4-day adult  (1191) Cadmium 50 mM 6 hrs, larvae L3  (1160) Cadmium 50 mM 12 hrs, larvae L3  (1270) Cadmium 50 mM 48 hrs, 4-day adult  (989) Cadmium 100 mM 48 hrs, 4-day adult  (1115) Copper 0.5 mM 12 hrs, larvae L3  (1188) Copper 15 mM 48 hrs, 4-day adult  (333) Zinc 5 mM 12 hrs, larvae L3  (1033) Zinc 4.5 mM 48 hrs, 4-day adult  (551) Ethanol 2.5% 3 hrs, larvae L3  (1187) Ethanol 5% 3 hrs, larvae L3  (1193) Ethanol 10% 3 hrs, larvae L3  (1250) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1304) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (1254) Caffeine 25 mg/ml 48 hrs, 4-day adult  (692) Paraquat 5 mM 48 hrs, 4-day adult  (1114) Paraquat 10 mM 48 hrs, 4-day adult  (1180) Rotenone 2 μg 12 hrs, larvae L3  (1378) Rotenone 8 μg 12 hrs, larvae L3  (1811) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (1017) cold shock, 4-day adult  (857) heat shock, 4-day adult  (1191) Cadmium 50 mM 6 hrs, larvae L3  (1160) Cadmium 50 mM 12 hrs, larvae L3  (1270) Cadmium 50 mM 48 hrs, 4-day adult  (989) Cadmium 100 mM 48 hrs, 4-day adult  (1115) Copper 0.5 mM 12 hrs, larvae L3  (1188) Copper 15 mM 48 hrs, 4-day adult  (333) Zinc 5 mM 12 hrs, larvae L3  (1033) Zinc 4.5 mM 48 hrs, 4-day adult  (551) Ethanol 2.5% 3 hrs, larvae L3  (1187) Ethanol 5% 3 hrs, larvae L3  (1193) Ethanol 10% 3 hrs, larvae L3  (1250) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1304) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (1254) Caffeine 25 mg/ml 48 hrs, 4-day adult  (692) Paraquat 5 mM 48 hrs, 4-day adult  (1114) Paraquat 10 mM 48 hrs, 4-day adult  (1180) Rotenone 2 μg 12 hrs, larvae L3  (1378) Rotenone 8 μg 12 hrs, larvae L3  (1811) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1017 cold shock, 4-day adult    857 heat shock, 4-day adult    1191 Cadmium 50 mM 6 hrs, larvae L3    1160 Cadmium 50 mM 12 hrs, larvae L3    1270 Cadmium 50 mM 48 hrs, 4-day adult    989 Cadmium 100 mM 48 hrs, 4-day adult    1115 Copper 0.5 mM 12 hrs, larvae L3    1188 Copper 15 mM 48 hrs, 4-day adult    333 Zinc 5 mM 12 hrs, larvae L3    1033 Zinc 4.5 mM 48 hrs, 4-day adult    551 Ethanol 2.5% 3 hrs, larvae L3    1187 Ethanol 5% 3 hrs, larvae L3    1193 Ethanol 10% 3 hrs, larvae L3    1250 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1304 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1254 Caffeine 25 mg/ml 48 hrs, 4-day adult    692 Paraquat 5 mM 48 hrs, 4-day adult    1114 Paraquat 10 mM 48 hrs, 4-day adult    1180 Rotenone 2 μg 12 hrs, larvae L3    1378 Rotenone 8 μg 12 hrs, larvae L3    1811 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_22 mE1_20_mRNA_expression_cluster_01
External Data & Images
Linkouts	BDGP expression data • AT27980 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039359 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4759-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4pnr-MD237 RpL27GD11420 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of RpL27 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RpL27 Class Mutagen Stocks Known lesion RpL27GD11420 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpL27KK100445 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11420} NA P{KK100445} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
centrosome duplication inferred from mutant phenotype (Müller et al., 2010) centrosome organization inferred from mutant phenotype (Müller et al., 2010) mitotic spindle elongation inferred from mutant phenotype (Goshima et al., 2007) mitotic spindle organization inferred from mutant phenotype (Goshima et al., 2007)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
structural constituent of ribosome inferred from sequence or structural similarity with Saccharomyces RPL27A (FlyBase, 1992-)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity with Saccharomyces RPL27A (FlyBase, 1992-)
Cellular Component
CV term Evidence References
cytosolic large ribosomal subunit inferred from sequence or structural similarity with Saccharomyces RPL27A (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RpL27 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68014 DroID - A comprehensive database of gene and protein interactions. • FBgn0039359 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43103
Orthologs
OrthoDB Orthologs (50) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG689576 Dipteran inclusive ortholog search EOG69CQJ5 Insect inclusive ortholog search EOG6M386C Arthropod inclusive ortholog search EOG6Z08PF Metazoa inclusive ortholog search EOG6CK7CK
Orthologs in Drosophila Species (EOG689576)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\RpL27     Drosophila simulans   Dsim\GD18180 Y   Drosophila sechellia   Dsec\GM10227 Y   Drosophila erecta   Dere\GG12227 Y   Drosophila yakuba   Dyak\GE10675 Y   Drosophila ananassae   Dana\GF18237 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA18411 Y   Drosophila persimilis   Dper\GL22302 Y   Drosophila willistoni   Dwil\GK14392 Y   Drosophila virilis   Dvir\GJ10202 Y   Drosophila mojavensis   Dmoj\GI10350 Y   Drosophila grimshawi   Dgri\GH18602 Y
Orthologs in non-Drosophila Dipterans (EOG69CQJ5)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011587   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014838   Anopheles gambiae Malaria mosquito  Agam\AGAP011687   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ005878
Orthologs in non-Dipteran Insects (EOG6M386C)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\RpL27   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012587   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH11996   Atta cephalotes Leafcutter ant  Acep\ACEP23715   Camponotus floridanus Florida carpenter ant  Cflo\CFLO16516   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20162   Linepithema humile Argentine ant  Lhum\LH24397   Pogonomyrmex barbatus Red harvester ant  Pbar\PB24599   Solenopsis invicta Red fire ant  Sinv\SINV16050   Acyrthosiphon pisum Pea aphid  Apim\ACYPI000085   Bombyx mori Silkmoth  Bmor\RpL27   Pediculus humanus Human body louse  Phum\PHUM257880   Tribolium castaneum Red flour beetle  Tcas\TC001671
Orthologs in non-Insect Arthropods (EOG6Z08PF)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\sprA   Ixodes scapularis Deer tick  Isca\ISCW005008
Orthologs in non-Arthropod Metazoa (EOG6CK7CK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\rpl-27   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019788gn   Danio rerio Zebrafish  Drer\rpl27   Xenopus tropicalis Western clawed frog  Xtro\rpl27   Gallus gallus Domestic chicken  Ggal\RPL27   Mus musculus House mouse  Mmus\Rpl27   Mus musculus House mouse  Mmus\Rpl27-ps1   Mus musculus House mouse  Mmus\Gm4825   Mus musculus House mouse  Mmus\Rpl27   Rattus norvegicus Norway rat  Rnor\RGD1565900   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000037933   Rattus norvegicus Norway rat  Rnor\RGD1563835   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000036655   Rattus norvegicus Norway rat  Rnor\LOC688784   Rattus norvegicus Norway rat  Rnor\RGD1561870   Rattus norvegicus Norway rat  Rnor\Rpl27   Rattus norvegicus Norway rat  Rnor\RGD1560069   Rattus norvegicus Norway rat  Rnor\LOC680808   Homo sapiens Human  Hsap\RPL27
Human Orthologs (1)
Gene OMIM HGNC Hsap\RPL27
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD18180 Drosophila sechellia Dsec\GM10227 Drosophila erecta Dere\GG12227 Drosophila yakuba Dyak\GE10675 Drosophila ananassae Dana\GF18237 Drosophila pseudoobscura pseudoobscura Dpse\GA18411 Drosophila persimilis Dper\GL22302 Drosophila willistoni Dwil\GK14392 Drosophila virilis Dvir\GJ10202 Drosophila mojavensis Dmoj\GI10350 Drosophila grimshawi Dgri\GH18602
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v103401 P{KK100445}VIE-260B v21943 w1118; P{GD11420}v21943
Genomic Clones ( 2 )
	BACR09D08 BACR48J06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 566 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT27980
Other clones	yak-ad_CG4759
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH03494 GH07866 GH08218 GH09763 GH15708 GH20452 GH23050 GM04835 GM06008 GM06907 GM12876 GM13040 GM14428 GM22337 GM25453 GM28693 LD22251 LD22959 LD38936 LD43264 LD47374 LP01571 LP02015 LP04445 LP04451 LP04956 LP05516 LP07014 LP18827 LP21659 LP23881 LP24019 RE02221 RE02709 RE04595 RE05550 RE10705 RE14308 RE14782 RE18669 RE22131 RE27102 RE27705 RE27760 RE28345 RE32475 RE32567 RE32655 RE34108 RE36822 RE37096 RE38324 RE39678 RE39868 RE42948 RE44768 RE45433 RE45483 RE46578 RE52369 RE54415 RE57503 RE58149 RE59572 RE60330 RE61901 RE62392 RE62759 RE62832 RE62992 RE63393 RE64787 RE64810 RE66481 RE66710 RE67427 RE67429 RE70090 RE70924 RE71882 RE73227 RE73313 RH02219 RH02237 RH05222 RH07222 RH11175 RH11828 RH13657 RH14508 RH14983 RH14985 RH15978 RH25847 RH30711 RH39515 RH39915 RH41304 RH50674 RH51886 RH56229 RH59129 RH60075 RH60494 RH61177 RH62063 RH69511 RH69842 SD03913 SD11165 SD13088 SD13550 SD15072 SD15487 SD15629 SD16153 SD17938 SD18966 SD21946 SD24581 SD26833 SD27940
Other clones	105155 107995 118899 124217 149653 158762 166261 191635 286236 286837 287112 287840 291899 295139 295228 295929 296195 296339 296693 297199 299155 558113 569444 569944 Dmel_dig_003721_0637_0546 Dmel_dig_007283_0609_3751 Dmel_dig_011352_0654_3620 Dmel_dig_011726_0691_1014 Dmel_dig_011819_0647_2613 Dmel_dig_015275_0683_1583 Dmel_dig_015513_0649_0784 Dmel_dig_015521_0685_2706 Dmel_dig_015975_0708_3215 Dmel_dig_016297_0647_0775 Dmel_dig_017420_0598_1876 Dmel_dig_018242_0589_1094 Dmel_dig_018571_0631_0391 Dmel_dig_019918_0615_3602 Dmel_dig_020295_0588_3361 Dmel_neb_001493_0898_3615 Dmel_neb_005865_0568_3631 Dmel_neb_006699_0110_3443 Dmel_neb_008750_0846_1497 Dmel_neb_012298_0620_2094 Dmel_neb_013420_0902_2180 Dmel_neb_014111_0910_2053 Dmel_neb_015027_0912_2207 EC00765 EC13445 EC22954 EC26462 EC27651 EC32266 EC32753 EC33266 EC34244 EC36765 EC37462 EC40910 EC051325 EK062222 EK062261 EK063210 EK088508 EK089037 EK092259 EK130548 EK155015 EK180153 EK225706 EK230251 EK234184 EK238364 EK246827 EK262012 EK295051 EN00923 EN01335 EN02308 EN02662 EN02701 EN05307 EN05816 EN08246 EN08515 EN08603 EN09945 EN10237 EN13022 EN13237 EN13842 EN14914 EN15729 EN15935 EN17348 ESG018b.E21_H10 ESG0115d.B21_D03 FGA001G10 FGA001G11 FGC001A11 FGC012G11 FGC018G05 FGC019F08 FGC021H03 FGC023G02 FGC025F12 FGC032B08 FGH101D05 FGH102E07 FGH108C11 FGH110A09 FGH119B06 FGH119D02 FGH127H09 FGH129D05 FGM102B03 FGM222A09 FGM223C02 FGM227H02 FGM230H07 FGM231C10 FGM301F02 FGM317H02 FGX001E09 IP07187 IP17483 LD46436 LP10636 RE29576 RE32028 RE52824 RE56657 RE64014 RH01009 RH06196 RH08107 RH08402 RH09453 RH10079 RH17158 RH18212 RH19037 RH19943 RH19968 RH20020 RH22455 RH26917 RH28732 RH32147 RH35133 RH35658 RH37094 RH38378 RH42546 RH42585 RH43406 RH46153 RH49660 RH52138 RH53871 RH55054 RH64202 RH68728 RH70070 RH70502 RH70728 RH70852 RH72051 RH74733 RP003003850 RP003005055 RP003006216 RP003007195 RP003009560 RP003009961 RP003010662 RP003011657 RP003014703 RP003021730 RP003022102 RP003023402 RP003024580 RP003026234 RP003026877 RP003028866 RP003033162 RP003034832 RP003037557 RP003040790 RP003044506 RP003046209 RP003047772 RP003048515 RP003052353 RP003058092 RP003059421 RP003065110 RP003065870 RP003066729 RP003067279 RP003068698 RP003070005 RP003071999 RP003077457 RP003079064 RP003080770 RP003083990 RP003084908 RP003092647 RP003095746 RP003100752 RP003103745 RP003104452 RP003105241 RP003106407 RP003107436 RP003109535 RP003111090 RP003111928 RP003112143 RP003113786 RP003116761 RP003121084 RP003122504 RP003126831 RP003130202 RP003132110 RP003133558 RP003137620 RP003138585 RP003140361 RP003145381 RP003146716 RP003148056 RP003150660 RP003157141 RP003159176 RP003159805 RP003160303 RP003161177 RP003165066 RP003173083 RP003176634 RP003177073 RP003178806 RP003181300 RP003181823 RP003182253 RP003183060 RP003184038 RP003184526 RP003184747 RP003192052 RP003192622 RP003193035 RP003193724 RP003195698 RP003204197 RP003204808 RP003205355 RP003209013 RP003213169 RP003226116 RP003230014 RP003234893 RP003236867 RP003241269 RP003242669 RP003259721 RP003260279 RP003260345 RP003265355 RP003272079 RP003275465 RP003277637 RP003278728 RP003278888 RP003290165 RP003291394 RP003293466 RP003302975 RP003305791 RP003306596 RP003308560 RP003314698 RP003316887 RP003319113 RP003323967 RP003324369 RP003330861 RP003337955 RP003341028 RP003341101 RP003357101 RP003360282 RP003366115 RP003368091 RP003369565 RP003372771 RP003377244 RP003378285 RP003378291 RP003379965 RP003384100 RP003384581 RP003387292 RP003389702 RP003390341 RP003395723 RP003396138 RP003401498 RP003406418 RP003407125 RP003407686 RP003408115 RP003410838 RP003411240 RP003411320 RP003411611 RP003412485 RP003413226 RP003417069 RP003417825 RP003420960 RP003421957 RP003422939 RP003423588 RP003424636 RP003425001 RP003425840 RP003426223 RP003431041 RP003431409 RP003432481 RP003436713 RP003437322 RP003437533 RP003441685 RP003443923 RP003444554 RP003444982 RP003447498 RP003450888 RP003452910 RP003454664 RP003454731 RP003455257 RP003455271 RP003456482 RP003460725 RP003461716 RP003461946 RP003462818 RP003463807 RP003465491 RP003465624 RP003469862 RP003473516 RP003474625 RP003476870 RP003476897 RP003478675 RP003479904 RP003480985 RP003485873 RP003490468 RP003491415 RP003492135 RP003493774 RP003498839 RP003499992 RP003505643 RP003505685 RP003507532 RP003509093 RP003511074 RP003512517 RP003515915 RP003517427 RP003519841 RP003520866 RP003520907 RP003522139 RP003522955 RP003523331 RP003528131 RP003529934 RP003531682 RP003535455 RP003535527 RP003537428 RP003537464 RP003537897 RP003538295 RP003539209 RP003541512 RP003541558 RP003542247 RP003543824 RP003547181 RP003549694 RP003552704 RP003553504 RP003555802 RP003559893 RP003566228 RP003566457 RP003569649 RP003569971 RP003585746 RP003592921 RP003594262 RP003596947 RP003597811 RP003606776 RP003609619 RP003611111 RP003617827 RP003618110 RP003620602 RP003621875 RP003624912 RP003630561 RP003630593 RP003632683 RP003637896 RP003638522 RP003638544 RP003638746 RP003640129 RP003640620 RP003642231 RP003643308 RP003643968 RP003647274 RP003647764 RP003651268 RP003653722 RP003666233 RP003668061 RP003672944 RP003673567
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039359 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43103
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	"RpL27" likely corresponds to "M(3)96CF". (Marygold et al., 2007)
Other Comments
	Haploinsufficient locus. (Cook et al., 2012) RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA. (Goshima et al., 2007) Likely Minute gene. (Marygold et al., 2007) Deletions removing RpL27 but no other cytoplasmic ribosomal protein-encoding genes show Minute phenotypes. (Marygold et al., 2007) RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143160 NM_001276037 NM_001276038 NM_001276039 RefSeq (Proteins) • NP_651417 NP_001262966 NP_001262967 NP_001262968 DDBJ / EMBL / GenBank • AAF56495 AAL48449 AGB96346 AGB96347 AGB96348 AY070827 BF491278 Entrez Gene - A searchable database of RefSeq genes. • 43103 UniProtKB/TrEMBL • Q9VBN5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L27e, conserved site (IPR018262) Ribosomal protein L27e (IPR001141) KOW (IPR005824) Ribosomal protein L2 domain 2 (IPR014722) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • AT27980
Linkouts
	BioGRID - A database of protein and genetic interactions • 68014 DroID - A comprehensive database of gene and protein interactions. • FBgn0039359 DRSC - Results from RNAi screens. • FBgn0039359 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039359 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4759-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039359 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43103 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43103 modMine - Data generated by the modENCODE project. • FBgn0039359
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG4759 (Boutros et al., 2004, Goshima et al., 2007, Marygold et al., 2007, Keleman et al., 2009.8.5, Kim et al., 2010, Cammarato et al., 2011, Yano et al., 2012) RpL27 (Kallappagoudar et al., 2010, Marygold et al., 2007, Kim et al., 2010, Friedman et al., 2011, Cook et al., 2012, Killip and Grewal, 2012) RPL27 (Coléno-Costes et al., 2012) RpL27e (Goshima et al., 2007)
Name Synonym	Ribosomal protein L27 (Ashburner and Marygold, 2004.7.2, Cammarato et al., 2011, Yano et al., 2012)
Secondary FlyBase IDs
References ( 28 )
Generate a list of	All references relating to this gene ( 28 )
List References by type	Research paper  ( 12 ) Supplementary material  ( 7 ) Personal communication to FlyBase  ( 4 ) FlyBase analysis  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 7 )
	Coléno-Costes et al., 2012, PLoS Genet. 8(10): e1003006 New partners in regulation of gene expression: the enhancer of trithorax and polycomb corto interacts with methylated ribosomal protein l12 via its chromodomain. [FBrf0219702] Cook et al., 2012, Genome Biol. 13(3): R21 The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome. [FBrf0219066] Crawford et al., 2012, Cell Death Differ. 19(12): 2040--2048 Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis. [FBrf0220233] Killip and Grewal, 2012, Dev. Biol. 371(2): 191--202 DREF is required for cell and organismal growth in Drosophila and functions downstream of the nutrition/TOR pathway. [FBrf0219592] Yano et al., 2012, J. Neurogenet. 26(1): 53--63 Identification of proteasome components required for apical localization of chaoptin using functional genomics. [FBrf0217843] Booker et al., 2011, BMC Genomics 12: 50 False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Friedman et al., 2011, Sci. Signal. 4(196): rs10 Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. [FBrf0216513] Show all research papers ...