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Gene Dmel\CG5886

General Information
Symbol	Dmel\CG5886	Species	D. melanogaster
Name		Annotation symbol	CG5886
Feature type	protein_coding_gene	FlyBase ID	FBgn0039379
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	96F3-96F4	Sequence location	3R:21,677,376..21,679,727 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5886 (FBgn0039379). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Taxilin. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during late pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval fat body, larval salivary gland, adult ovary, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1641692_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG5886. Gene sequence location is 3R:21677376..21679727.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN22944 HFA15908
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 96F3-96F4   Limits computationally determined from genome sequence between P{PZ}l(3)rQ197rQ197 and P{lacW}scribj7B3
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5886 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5886-RA FBtr0084907  NM_143178   1888   515
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5886-PA   FBpp0084281   59.0   515   8.64     NP_651435   AAF56518
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Taxilin (IPR019132)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA263908   AA736159   AA801919   AE014297 AAF56518   AI061999   AI062113   AI513090   AI944740   AY047502 AAK77234   BF486194   BF486506   BF488291   BF490259   BF490719   BF491189   BF491683   BF492139   BF493515   BF495437   BF495822   BF495847   BF496162   BF497421   BF498207   BF498357   BF498406   BF498596   BF499070   BF499867   BF502757   BF503950   BF504947   BF506403   BF506413   BF506542   BF506769   BG632933   BG633735   BI165034   BI368178   BI371853   BI371865   BI374825   BQ103182   CO288833   CZ470741   CZ470742   EC058710   EC089202   GH748052   GH748875   GH749806   GH750501   GH751789   GH753018   GH756378   GH756386   GH759265   GH760428   GH773124   GH775064   GH775084   GH776082   GH776731   GH781701   GH786735   GH786953   GH787723   GH791031   GH791169   GH793765   GH796558   GH796936   GH799547   GH802667   GH804606   GH806204   GH807715   GH808362   GH808407   GH808512   GH809000   GH809700   GH810518   GH810994   GH811483   GH812392   GH812970   GH813116   GH813332   GH814224   GH814562   GH815576   GH816842   GH818047   GH818543   GH819775   GH819885   GH819942   GH823104   GH823465   GH824203   GH825083   GH825692   GH827195   GH828362   GH831177   GH835606   GH837066   GH837719   GH838061   GH839443   GH840281   GH844554   GH847166   GH847679   GH854411   GH855851   GH857488   GH858547   GH859667   GH861658   GH862822   GH864156   GH865945   GH866863   GH866892   GH868356   GH875877   GH876653   GH877631   GH877782   GH879309   GH880968   GH884141   GH885403   GH886767   GH892157   GH892610   GH895987   GH898379   GH898481   GH901554   GH907522   GH908121   GH908480   GH909229   GH911060   GH913065   GH914291   GH914692   GH916481   GH917350   GH920128   GH922046   GH925238   GH929675   GH931787   GH934110   GH935399
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VBL3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039379    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039379 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during late pupal stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039379 expression level Developmental Stage   Expression Level embryo 00-02hr    3894 embryo 02-04hr    2114 embryo 04-06hr    1861 embryo 06-08hr    1778 embryo 08-10hr    2115 embryo 10-12hr    3275 embryo 12-14hr    3156 embryo 14-16hr    2504 embryo 16-18hr    2414 embryo 18-20hr    1566 embryo 20-22hr    457 embryo 22-24hr    580 larva L1    958 larva L2    1356 larva L3 12hr old    1303 larva L3 puffstage 1-2    1230 larva L3 puffstage 3-6    1491 larva L3 puffstage 7-9    1858 white prepupae new    1810 white prepupae 12hr    2490 white prepupae 24hr    3883 pupae 2d postWPP    6163 pupae 3d postWPP    5855 pupae 4d postWPP    2572 adult male 01day    3970 adult male 05day    5042 adult male 30day    4408 adult female 01day    1199 adult female 05day    2560 adult female 30day    2599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3894) embryo 02-04hr  (2114) embryo 04-06hr  (1861) embryo 06-08hr  (1778) embryo 08-10hr  (2115) embryo 10-12hr  (3275) embryo 12-14hr  (3156) embryo 14-16hr  (2504) embryo 16-18hr  (2414) embryo 18-20hr  (1566) embryo 20-22hr  (457) embryo 22-24hr  (580) larva L1  (958) larva L2  (1356) larva L3 12hr old  (1303) larva L3 puffstage 1-2  (1230) larva L3 puffstage 3-6  (1491) larva L3 puffstage 7-9  (1858) white prepupae new  (1810) white prepupae 12hr  (2490) white prepupae 24hr  (3883) pupae 2d postWPP  (6163) pupae 3d postWPP  (5855) pupae 4d postWPP  (2572) adult male 01day  (3970) adult male 05day  (5042) adult male 30day  (4408) adult female 01day  (1199) adult female 05day  (2560) adult female 30day  (2599) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3894) embryo 02-04hr  (2114) embryo 04-06hr  (1861) embryo 06-08hr  (1778) embryo 08-10hr  (2115) embryo 10-12hr  (3275) embryo 12-14hr  (3156) embryo 14-16hr  (2504) embryo 16-18hr  (2414) embryo 18-20hr  (1566) embryo 20-22hr    457 embryo 22-24hr    580 larva L1    958 larva L2    1356 larva L3 12hr old    1303 larva L3 puffstage 1-2    1230 larva L3 puffstage 3-6  1491 larva L3 puffstage 7-9  (1858) white prepupae new  (1810) white prepupae 12hr  (2490) white prepupae 24hr  (3883) pupae 2d postWPP  (6163) pupae 3d postWPP  (5855) pupae 4d postWPP  (2572) adult male 01day  (3970) adult male 05day  (5042) adult male 30day  (4408) adult female 01day    1199 adult female 05day  (2560) adult female 30day  (2599) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3894 embryo 02-04hr    2114 embryo 04-06hr    1861 embryo 06-08hr    1778 embryo 08-10hr    2115 embryo 10-12hr    3275 embryo 12-14hr    3156 embryo 14-16hr    2504 embryo 16-18hr    2414 embryo 18-20hr    1566 embryo 20-22hr    457 embryo 22-24hr    580 larva L1    958 larva L2    1356 larva L3 12hr old    1303 larva L3 puffstage 1-2    1230 larva L3 puffstage 3-6    1491 larva L3 puffstage 7-9    1858 white prepupae new    1810 white prepupae 12hr    2490 white prepupae 24hr    3883 pupae 2d postWPP    6163 pupae 3d postWPP    5855 pupae 4d postWPP    2572 adult male 01day    3970 adult male 05day    5042 adult male 30day    4408 adult female 01day    1199 adult female 05day    2560 adult female 30day    2599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3894 embryo 02-04hr    2114 embryo 04-06hr    1861 embryo 06-08hr    1778 embryo 08-10hr    2115 embryo 10-12hr    3275 embryo 12-14hr    3156 embryo 14-16hr    2504 embryo 16-18hr    2414 embryo 18-20hr    1566 embryo 20-22hr    457 embryo 22-24hr    580 larva L1    958 larva L2    1356 larva L3 12hr old    1303 larva L3 puffstage 1-2    1230 larva L3 puffstage 3-6    1491 larva L3 puffstage 7-9    1858 white prepupae new    1810 white prepupae 12hr    2490 white prepupae 24hr    3883 pupae 2d postWPP    6163 pupae 3d postWPP    5855 pupae 4d postWPP    2572 adult male 01day    3970 adult male 05day    5042 adult male 30day    4408 adult female 01day    1199 adult female 05day    2560 adult female 30day    2599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039379 expression level Developmental Stage   Expression Level embryo 00-02hr    3894 embryo 02-04hr    2114 embryo 04-06hr    1861 embryo 06-08hr    1778 embryo 08-10hr    2115 embryo 10-12hr    3275 embryo 12-14hr    3156 embryo 14-16hr    2504 embryo 16-18hr    2414 embryo 18-20hr    1566 embryo 20-22hr    457 embryo 22-24hr    580 larva L1    958 larva L2    1356 larva L3 12hr old    1303 larva L3 puffstage 1-2    1230 larva L3 puffstage 3-6    1491 larva L3 puffstage 7-9    1858 white prepupae new    1810 white prepupae 12hr    2490 white prepupae 24hr    3883 pupae 2d postWPP    6163 pupae 3d postWPP    5855 pupae 4d postWPP    2572 adult male 01day    3970 adult male 05day    5042 adult male 30day    4408 adult female 01day    1199 adult female 05day    2560 adult female 30day    2599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3894) embryo 02-04hr  (2114) embryo 04-06hr  (1861) embryo 06-08hr  (1778) embryo 08-10hr  (2115) embryo 10-12hr  (3275) embryo 12-14hr  (3156) embryo 14-16hr  (2504) embryo 16-18hr  (2414) embryo 18-20hr  (1566) embryo 20-22hr  (457) embryo 22-24hr  (580) larva L1  (958) larva L2  (1356) larva L3 12hr old  (1303) larva L3 puffstage 1-2  (1230) larva L3 puffstage 3-6  (1491) larva L3 puffstage 7-9  (1858) white prepupae new  (1810) white prepupae 12hr  (2490) white prepupae 24hr  (3883) pupae 2d postWPP  (6163) pupae 3d postWPP  (5855) pupae 4d postWPP  (2572) adult male 01day  (3970) adult male 05day  (5042) adult male 30day  (4408) adult female 01day  (1199) adult female 05day  (2560) adult female 30day  (2599) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3894) embryo 02-04hr  2114 embryo 04-06hr  1861 embryo 06-08hr  1778 embryo 08-10hr  2115 embryo 10-12hr  (3275) embryo 12-14hr  (3156) embryo 14-16hr  (2504) embryo 16-18hr  2414 embryo 18-20hr  1566 embryo 20-22hr    457 embryo 22-24hr    580 larva L1    958 larva L2    1356 larva L3 12hr old    1303 larva L3 puffstage 1-2    1230 larva L3 puffstage 3-6  1491 larva L3 puffstage 7-9  1858 white prepupae new  1810 white prepupae 12hr  (2490) white prepupae 24hr  (3883) pupae 2d postWPP  (6163) pupae 3d postWPP  (5855) pupae 4d postWPP  (2572) adult male 01day  (3970) adult male 05day  (5042) adult male 30day  (4408) adult female 01day    1199 adult female 05day  (2560) adult female 30day  (2599) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3894 embryo 02-04hr    2114 embryo 04-06hr    1861 embryo 06-08hr    1778 embryo 08-10hr    2115 embryo 10-12hr    3275 embryo 12-14hr    3156 embryo 14-16hr    2504 embryo 16-18hr    2414 embryo 18-20hr    1566 embryo 20-22hr    457 embryo 22-24hr    580 larva L1    958 larva L2    1356 larva L3 12hr old    1303 larva L3 puffstage 1-2    1230 larva L3 puffstage 3-6    1491 larva L3 puffstage 7-9    1858 white prepupae new    1810 white prepupae 12hr    2490 white prepupae 24hr    3883 pupae 2d postWPP    6163 pupae 3d postWPP    5855 pupae 4d postWPP    2572 adult male 01day    3970 adult male 05day    5042 adult male 30day    4408 adult female 01day    1199 adult female 05day    2560 adult female 30day    2599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3894 embryo 02-04hr    2114 embryo 04-06hr    1861 embryo 06-08hr    1778 embryo 08-10hr    2115 embryo 10-12hr    3275 embryo 12-14hr    3156 embryo 14-16hr    2504 embryo 16-18hr    2414 embryo 18-20hr    1566 embryo 20-22hr    457 embryo 22-24hr    580 larva L1    958 larva L2    1356 larva L3 12hr old    1303 larva L3 puffstage 1-2    1230 larva L3 puffstage 3-6    1491 larva L3 puffstage 7-9    1858 white prepupae new    1810 white prepupae 12hr    2490 white prepupae 24hr    3883 pupae 2d postWPP    6163 pupae 3d postWPP    5855 pupae 4d postWPP    2572 adult male 01day    3970 adult male 05day    5042 adult male 30day    4408 adult female 01day    1199 adult female 05day    2560 adult female 30day    2599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0039379    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0039379 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval fat body, larval salivary gland, adult ovary, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0039379 expression level Tissue   Expression Level Larval Central Nervous System    191.075 Larval Midgut    48.2 Larval Hindgut    90.5 Larval Malpighian Tubules    56.9 Larval Fat Body    183.1 Larval Salivary Gland    171.4 Larval Trachea    98.4 Larval Carcass    249.7 Adult Head no informative data Adult Eye    51.5 Adult Brain    111.6 Adult Thoracic-Abdominal Ganglion    79.2 Adult Crop    141 Adult Midgut    40.2 Adult Hindgut    81.4 Adult Malpighian Tubules    51.2 Adult Fat Body    44.5 Adult Salivary Gland no informative data Adult Heart    57.05 Adult VirginFemale Spermatheca    98.6 Adult InseminatedFemale Spermatheca    91.2 Adult Ovary    328.8 Adult Testis    997 Adult Male Accessory Gland    95.7 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    191.075 Larval Midgut    48.2 Larval Hindgut    90.5 Larval Malpighian Tubules    56.9 Larval Fat Body    183.1 Larval Salivary Gland    171.4 Larval Trachea    98.4 Larval Carcass    249.7 Adult Head no informative data Adult Eye    51.5 Adult Brain    111.6 Adult Thoracic-Abdominal Ganglion    79.2 Adult Crop    141 Adult Midgut    40.2 Adult Hindgut    81.4 Adult Malpighian Tubules    51.2 Adult Fat Body    44.5 Adult Salivary Gland no informative data Adult Heart    57.05 Adult VirginFemale Spermatheca    98.6 Adult InseminatedFemale Spermatheca    91.2 Adult Ovary    328.8 Adult Testis  (997) Adult Male Accessory Gland    95.7 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    191.075 Larval Midgut    48.2 Larval Hindgut    90.5 Larval Malpighian Tubules    56.9 Larval Fat Body    183.1 Larval Salivary Gland    171.4 Larval Trachea    98.4 Larval Carcass    249.7 Adult Head no informative data Adult Eye    51.5 Adult Brain    111.6 Adult Thoracic-Abdominal Ganglion    79.2 Adult Crop    141 Adult Midgut    40.2 Adult Hindgut    81.4 Adult Malpighian Tubules    51.2 Adult Fat Body    44.5 Adult Salivary Gland no informative data Adult Heart    57.05 Adult VirginFemale Spermatheca    98.6 Adult InseminatedFemale Spermatheca    91.2 Adult Ovary    328.8 Adult Testis    997 Adult Male Accessory Gland    95.7 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    191.075 Larval Midgut    48.2 Larval Hindgut    90.5 Larval Malpighian Tubules    56.9 Larval Fat Body    183.1 Larval Salivary Gland    171.4 Larval Trachea    98.4 Larval Carcass    249.7 Adult Head no informative data Adult Eye    51.5 Adult Brain    111.6 Adult Thoracic-Abdominal Ganglion    79.2 Adult Crop    141 Adult Midgut    40.2 Adult Hindgut    81.4 Adult Malpighian Tubules    51.2 Adult Fat Body    44.5 Adult Salivary Gland no informative data Adult Heart    57.05 Adult VirginFemale Spermatheca    98.6 Adult InseminatedFemale Spermatheca    91.2 Adult Ovary    328.8 Adult Testis    997 Adult Male Accessory Gland    95.7 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0039379 expression level Tissue   Expression Level Larval Central Nervous System    191.075 Larval Midgut    48.2 Larval Hindgut    90.5 Larval Malpighian Tubules    56.9 Larval Fat Body    183.1 Larval Salivary Gland    171.4 Larval Trachea    98.4 Larval Carcass    249.7 Adult Head no informative data Adult Eye    51.5 Adult Brain    111.6 Adult Thoracic-Abdominal Ganglion    79.2 Adult Crop    141 Adult Midgut    40.2 Adult Hindgut    81.4 Adult Malpighian Tubules    51.2 Adult Fat Body    44.5 Adult Salivary Gland no informative data Adult Heart    57.05 Adult VirginFemale Spermatheca    98.6 Adult InseminatedFemale Spermatheca    91.2 Adult Ovary    328.8 Adult Testis    997 Adult Male Accessory Gland    95.7 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    191.075 Larval Midgut    48.2 Larval Hindgut    90.5 Larval Malpighian Tubules    56.9 Larval Fat Body    183.1 Larval Salivary Gland    171.4 Larval Trachea    98.4 Larval Carcass    249.7 Adult Head no informative data Adult Eye    51.5 Adult Brain    111.6 Adult Thoracic-Abdominal Ganglion    79.2 Adult Crop    141 Adult Midgut    40.2 Adult Hindgut    81.4 Adult Malpighian Tubules    51.2 Adult Fat Body    44.5 Adult Salivary Gland no informative data Adult Heart    57.05 Adult VirginFemale Spermatheca    98.6 Adult InseminatedFemale Spermatheca    91.2 Adult Ovary    328.8 Adult Testis  (997) Adult Male Accessory Gland    95.7 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    191.075 Larval Midgut    48.2 Larval Hindgut    90.5 Larval Malpighian Tubules    56.9 Larval Fat Body    183.1 Larval Salivary Gland    171.4 Larval Trachea    98.4 Larval Carcass    249.7 Adult Head no informative data Adult Eye    51.5 Adult Brain    111.6 Adult Thoracic-Abdominal Ganglion    79.2 Adult Crop    141 Adult Midgut    40.2 Adult Hindgut    81.4 Adult Malpighian Tubules    51.2 Adult Fat Body    44.5 Adult Salivary Gland no informative data Adult Heart    57.05 Adult VirginFemale Spermatheca    98.6 Adult InseminatedFemale Spermatheca    91.2 Adult Ovary    328.8 Adult Testis    997 Adult Male Accessory Gland    95.7 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    191.075 Larval Midgut    48.2 Larval Hindgut    90.5 Larval Malpighian Tubules    56.9 Larval Fat Body    183.1 Larval Salivary Gland    171.4 Larval Trachea    98.4 Larval Carcass    249.7 Adult Head no informative data Adult Eye    51.5 Adult Brain    111.6 Adult Thoracic-Abdominal Ganglion    79.2 Adult Crop    141 Adult Midgut    40.2 Adult Hindgut    81.4 Adult Malpighian Tubules    51.2 Adult Fat Body    44.5 Adult Salivary Gland no informative data Adult Heart    57.05 Adult VirginFemale Spermatheca    98.6 Adult InseminatedFemale Spermatheca    91.2 Adult Ovary    328.8 Adult Testis    997 Adult Male Accessory Gland    95.7 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head no informative data Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    51.5   NA  Brain    111.6   191.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    79.2   NA  Crop    141   48.2  Midgut    40.2   90.5  Hindgut    81.4   56.9  Malpighian Tubules    51.2   183.1  Fat Body    44.5   171.4  Salivary Gland    no informative data   NA  Heart    57.05   98.4  Trachea    NA   NA  VirginFemale Spermatheca    98.6   NA  InseminatedFemale Spermatheca    91.2   NA  Ovary    328.8   NA  Testis    997   NA  Male Accessory Gland    95.7   249.7  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_21
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039379 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5886-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG5886 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG5886GD11795 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG5886 Class Mutagen Stocks Known lesion CG5886c06503 piggyBac transposase 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5886 Class Mutagen Stocks Known lesion CG5886GD11795 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5886KK102848 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11795} NA P{KK102848} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}CG5886c06503 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5886 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68030 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039379 DroID - A comprehensive database of gene and protein interactions. • FBgn0039379 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43125
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16776 Dere\GG11428 Dgri\GH22303 Dmoj\GI22973 Dper\GL21538 Dpse\GA19203 Dsec\GM10269 Dsim\GD21238 Dvir\GJ22733 Dwil\GK12861 Dyak\GE23623
Curated drosophilid orthologs	Dpse\GA19203
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL002374-PA Aedes aegypti (mosquito) AGAP009667-PA Anopheles gambiae (mosquito) XP_001944177.1 Acyrthosiphon pisum (pea aphid) At5g50840.2 Arabidopsis thaliana (wall cress) 92132 Batrachochytrium dendrobatidis (chytrid fungus) 224972 Branchiostoma floridae (lancelet) 242928 Branchiostoma floridae (lancelet) ENSBTAP00000017100 Bos taurus (bovine) CN12482 Caenorhabditis brenneri (small nematode) CN26158 Caenorhabditis brenneri (small nematode) CBP25385 Caenorhabditis briggsae (nematode) CE24002 Caenorhabditis elegans (worm) ENSCAFP00000000403 Canis familiaris (dog) ENSCINP00000003348 Ciona intestinalis (sea squirt) JA12744 Caenorhabditis japonica (nematode) CPIJ011989 Culex pipens (mosquito) ENSCPOP00000010775 Cavia porcellus (guinea pig) 147970 Chlamidomonas reinhardtii (green alga) RP31389 Caenorhabditis remanei (nematode) 104506 Capitella spl (polychaete worm) 322027 Daphnia pulex (daphnia) ENSDARP00000094225 Danio rerio (zebra fish) ENSECAP00000016904 Equus caballus (horse) ENSGACP00000015542 Gymnopilus aculeatus (mushroom) ENSGALP00000005123 Gallus gallus (chicken) ENSGALP00000022390 Gallus gallus (chicken) ENSP00000362712 Homo sapiens (human) 106798 Lottia gigantea (owl limpet) 22116 Monocosta brevicollis (choanoflagellate) ENSMODP00000021822 Monodelphis domestica (gray opossum) ENSMMUP00000020438 Macaca mulatta (rhesus monkey) ENSMUSP00000081285 Mus musculus (house mouse) XP_001606274.1 Nasonia vitripennis (wasp) ENSOANP00000006089 Ornithorynchus anatinus (platypus) ENSORLP00000017701 Oryzias latipes (japanese killifish) LOC_Os03g17930.1 Oryza sativa (asian rice) PHUM006428-PA Pediculus humanus (human body louse) PP25997 Pristionchus pacificus (nematode) ENSPPYP00000022547 Pongo pygmaeus (orangutan) 155305 Phytophthora sojae (root rot pathogen) ENSPTRP00000037181 Pan troglodytes (chimpanzee) ENSRNOP00000016553 Rattus norvegicus (norway rat) 5049643 Sorghum bicolor (sorghum) Smp_164620 Schistosoma mansoni (trematode parasite) XP_780699.2 Strongylocentrotus purpuratus (purple sea urchin) XP_974016.1 Tribolium castaneum (red flour beetle) ENSTNIP00000012138 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000026322 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000011447 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14484 ISCW014074 FBgn0240796 FBgn0214870 FBgn0209837 FBgn0192688 FBgn0165220 JGI_V11_322027 FBgn0079200 FBgn0159131 FBgn0145700 FBgn0129761 FBgn0103728 FBgn0093797 CPIJ011989 BGIBMGA010055 ACYPI007588 ACYPI004376 AGAP009667 AAEL002374 PHUM060130 GLEAN_14163
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Harvard	- PBac{PB}CG5886c06503
VDRC	v106471 P{KK102848}VIE-260B v22216 w1118; P{GD11795}v22216
Genomic Clones ( 1 )
	BACR06K17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 156 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH01188
Other clones	DPiM_GH01188
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT01801 AT04364 AT05196 AT07093 AT08858 AT08870 AT09051 AT09338 AT09483 AT09515 AT09891 AT11585 AT12581 AT12793 AT12832 AT13035 AT13557 AT14639 AT18569 AT20414 AT20830 AT23528 AT26582 AT27279 AT27874 AT28481 AT29018 AT29454 GH01034 GH16406 GM03584 GM12289 LD07179 RE04835 RE54101 RE58863 RE58878 RE62507
Other clones	157135 bs04g12 CK01.88A.G2 EK069457 RP003024745 RP003026598 RP003040415 RP003044545 RP003050938 RP003051247 RP003056550 RP003071660 RP003073580 RP003075892 RP003077841 RP003078303 RP003080062 RP003090100 RP003091859 RP003098874 RP003099759 RP003102647 RP003103709 RP003121621 RP003123483 RP003124602 RP003126635 RP003129010 RP003131399 RP003134633 RP003135552 RP003136806 RP003141102 RP003147787 RP003148831 RP003151375 RP003152048 RP003154461 RP003154714 RP003157058 RP003162989 RP003169721 RP003170987 RP003175961 RP003176545 RP003193332 RP003198292 RP003198477 RP003203441 RP003205400 RP003210573 RP003221001 RP003221005 RP003221470 RP003222202 RP003222567 RP003222844 RP003224360 RP003224539 RP003229394 RP003242090 RP003242453 RP003245851 RP003253940 RP003259625 RP003263310 RP003278044 RP003280451 RP003292977 RP003293755 RP003298150 RP003306464 RP003311326 RP003320974 RP003322895 RP003333857 RP003343096 RP003343860 RP003357810 RP003365904 RP003366623 RP003368227 RP003386131 RP003395528 RP003413948 RP003422127 RP003429569 RP003445452 RP003465118 RP003473747 RP003478104 RP003489512 RP003490965 RP003492244 RP003497388 RP003498634 RP003504314 RP003508276 RP003515858 RP003520313 RP003522715 RP003524670 RP003528298 RP003537211 RP003561612 RP003577024 RP003578721 RP003588872 RP003598215 RP003602168 RP003618955 RP003626719 RP003644576 RP003653423 RP003660296 UUGC0580
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039379 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43125
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	ChEST reveals this is a target of Mef2. ChEST reveals this is a target of Mef2. (Junion et al., 2005)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143178 RefSeq (Proteins) • NP_651435 DDBJ / EMBL / GenBank • AAF56518 AAK77234 AI061999 AI062113 AI513090 AI944740 AY047502 CZ470741 CZ470742 Entrez Gene - A searchable database of RefSeq genes. • 43125 UniProtKB/TrEMBL • Q9VBL3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Taxilin (IPR019132)
Linkouts
	BioGRID - A database of protein and genetic interactions • 68030 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039379 DroID - A comprehensive database of gene and protein interactions. • FBgn0039379 DRSC - Results from RNAi screens. • FBgn0039379 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039379 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5886-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039379 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43125 InParanoid A subset of ortholog calls from InParanoid. • AAEL002374-PA Aedes aegypti (mosquito) AGAP009667-PA Anopheles gambiae (mosquito) XP_001944177.1 Acyrthosiphon pisum (pea aphid) At5g50840.2 Arabidopsis thaliana (wall cress) 92132 Batrachochytrium dendrobatidis (chytrid fungus) 224972 Branchiostoma floridae (lancelet) 242928 Branchiostoma floridae (lancelet) ENSBTAP00000017100 Bos taurus (bovine) CN12482 Caenorhabditis brenneri (small nematode) CN26158 Caenorhabditis brenneri (small nematode) CBP25385 Caenorhabditis briggsae (nematode) CE24002 Caenorhabditis elegans (worm) ENSCAFP00000000403 Canis familiaris (dog) ENSCINP00000003348 Ciona intestinalis (sea squirt) JA12744 Caenorhabditis japonica (nematode) CPIJ011989 Culex pipens (mosquito) ENSCPOP00000010775 Cavia porcellus (guinea pig) 147970 Chlamidomonas reinhardtii (green alga) RP31389 Caenorhabditis remanei (nematode) 104506 Capitella spl (polychaete worm) 322027 Daphnia pulex (daphnia) ENSDARP00000094225 Danio rerio (zebra fish) ENSECAP00000016904 Equus caballus (horse) ENSGACP00000015542 Gymnopilus aculeatus (mushroom) ENSGALP00000005123 Gallus gallus (chicken) ENSGALP00000022390 Gallus gallus (chicken) ENSP00000362712 Homo sapiens (human) 106798 Lottia gigantea (owl limpet) 22116 Monocosta brevicollis (choanoflagellate) ENSMODP00000021822 Monodelphis domestica (gray opossum) ENSMMUP00000020438 Macaca mulatta (rhesus monkey) ENSMUSP00000081285 Mus musculus (house mouse) XP_001606274.1 Nasonia vitripennis (wasp) ENSOANP00000006089 Ornithorynchus anatinus (platypus) ENSORLP00000017701 Oryzias latipes (japanese killifish) LOC_Os03g17930.1 Oryza sativa (asian rice) PHUM006428-PA Pediculus humanus (human body louse) PP25997 Pristionchus pacificus (nematode) ENSPPYP00000022547 Pongo pygmaeus (orangutan) 155305 Phytophthora sojae (root rot pathogen) ENSPTRP00000037181 Pan troglodytes (chimpanzee) ENSRNOP00000016553 Rattus norvegicus (norway rat) 5049643 Sorghum bicolor (sorghum) Smp_164620 Schistosoma mansoni (trematode parasite) XP_780699.2 Strongylocentrotus purpuratus (purple sea urchin) XP_974016.1 Tribolium castaneum (red flour beetle) ENSTNIP00000012138 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000026322 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000011447 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43125 modMine - Data generated by the modENCODE project. • FBgn0039379 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14484 ISCW014074 FBgn0240796 FBgn0214870 FBgn0209837 FBgn0192688 FBgn0165220 JGI_V11_322027 FBgn0079200 FBgn0159131 FBgn0145700 FBgn0129761 FBgn0103728 FBgn0093797 CPIJ011989 BGIBMGA010055 ACYPI007588 ACYPI004376 AGAP009667 AAEL002374 PHUM060130 GLEAN_14163
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5886 (Keleman et al., 2009.8.5, Zimmermann et al., 2006)
Name Synonym
Secondary FlyBase IDs
References ( 13 )
Research paper	Zimmermann et al., 2006, Dev. Dynamics 235(12): 3387--3395 Mes2, a MADF-containing transcription factor essential for Drosophila development. [FBrf0194335] Junion et al., 2005, Proc. Natl. Acad. Sci. USA 102(51): 18479--18484 Mapping Dmef2-binding regulatory modules by using a ChIP-enriched in silico targets approach. [FBrf0191443]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]