Gene model reviewed during 5.47
There is only one protein coding transcript and one polypeptide associated with this gene
Belongs to the multiprotein complex Integrator, at least composed of IntS1, IntS2, IntS3, IntS4, omd/IntS5, IntS6, defl/IntS7, IntS8, IntS9, IntS10, IntS11, IntS12, asun/IntS13 and IntS14 (PubMed:23097424). Within the complex, interacts with IntS1 and IntS9 (PubMed:23288851). Interaction with IntS1 is likely to be important for promoting 3'-end processing of snRNAs (PubMed:23288851).
The PHD-type zinc finger is not required for 3'-end snRNA processing.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\IntS12 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\IntS12 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: IntS12 CG5491