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Gene Dmel\CG14253

General Information
Symbol	Dmel\CG14253	Species	D. melanogaster
Name		Annotation symbol	CG14253
Feature type	protein_coding_gene	FlyBase ID	FBgn0039467
Gene Model Status	Current	Stock availability	9 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	97D12-97D12	Sequence location	3R:22,804,266..22,811,431 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG14253 (FBgn0039467). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, adult hindgut, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1625563_s_at completely aligns to an exonic region common to each of the 5 FlyBase-annotated transcript isoforms of CG14253. Gene sequence location is 3R:22804266..22811431.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	References Wertheim et al., 2011, Mol. Ecol. 20(5): 932--949 Clones FGM229E11
FB2012_01	Sequence features BKN25834 HFA14748
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 97D12-97D12   Limits computationally determined from genome sequence between P{PZ}sda03884 and P{PZ}btzrL203
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG14253 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG14253-RA FBtr0085074  NM_170300   1968   390 CG14253-RB FBtr0085070  NM_143260   1886   399 CG14253-RC FBtr0085071  NM_170301   2168   390 CG14253-RD FBtr0085073  NM_170302   2349   390 CG14253-RE FBtr0085072  NM_170303   2137   390
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG14253-PA   FBpp0084446   44.2   390   6.51     NP_733179   AAF56645 CG14253-PB   FBpp0084442   45.4   399   6.59     NP_651517   AAN14099 CG14253-PC   FBpp0084443   44.2   390   6.51     NP_733180   AAN14100 CG14253-PD   FBpp0084445   44.2   390   6.51     NP_733181   AAN14101 CG14253-PE   FBpp0084444   44.2   390   6.51     NP_733182   AAN14102
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF56645   AE014297 AAN14099   AE014297 AAN14100   AE014297 AAN14101   AE014297 AAN14102   AI114304   AI135518   AI293860   AI296186   AI455414   AY071638 AAL49260   BG640818   BI216052   BI357791   BI366239   BI366297   BI369684   BI373586   BI485075   BI486073   BI632414   BI632997   BI639531   BP546296   BP554384   BT100115   CL528250   CO183615   CO184278   CO264845   CO284114   CO284201   CO293835   CO305156   CO310404   CO338461   CZ470086   CZ470129   EC065799   EC075307   EC076054   EC209862   EC217197   EC217198   EC222576   EC246294   EC253007   EC264405   EL872555   EL872918   GH802017   GH840862   GH848478
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SYC5 Q9VB97
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039467    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039467 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039467 expression level Developmental Stage   Expression Level embryo 00-02hr    446 embryo 02-04hr    367 embryo 04-06hr    205 embryo 06-08hr    172 embryo 08-10hr    493 embryo 10-12hr    1023 embryo 12-14hr    805 embryo 14-16hr    574 embryo 16-18hr    1611 embryo 18-20hr    4228 embryo 20-22hr    5028 embryo 22-24hr    6399 larva L1    1465 larva L2    728 larva L3 12hr old    753 larva L3 puffstage 1-2    599 larva L3 puffstage 3-6    678 larva L3 puffstage 7-9    1989 white prepupae new    2899 white prepupae 12hr    595 white prepupae 24hr    337 pupae 2d postWPP    269 pupae 3d postWPP    325 pupae 4d postWPP    862 adult male 01day    468 adult male 05day    453 adult male 30day    450 adult female 01day    413 adult female 05day    381 adult female 30day    279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (446) embryo 02-04hr  (367) embryo 04-06hr  (205) embryo 06-08hr  (172) embryo 08-10hr  (493) embryo 10-12hr  (1023) embryo 12-14hr  (805) embryo 14-16hr  (574) embryo 16-18hr  (1611) embryo 18-20hr  (4228) embryo 20-22hr  (5028) embryo 22-24hr  (6399) larva L1  (1465) larva L2  (728) larva L3 12hr old  (753) larva L3 puffstage 1-2  (599) larva L3 puffstage 3-6  (678) larva L3 puffstage 7-9  (1989) white prepupae new  (2899) white prepupae 12hr  (595) white prepupae 24hr  (337) pupae 2d postWPP  (269) pupae 3d postWPP  (325) pupae 4d postWPP  (862) adult male 01day  (468) adult male 05day  (453) adult male 30day  (450) adult female 01day  (413) adult female 05day  (381) adult female 30day  (279) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    446 embryo 02-04hr    367 embryo 04-06hr    205 embryo 06-08hr    172 embryo 08-10hr    493 embryo 10-12hr    1023 embryo 12-14hr    805 embryo 14-16hr    574 embryo 16-18hr  (1611) embryo 18-20hr  (4228) embryo 20-22hr  (5028) embryo 22-24hr  (6399) larva L1  1465 larva L2    728 larva L3 12hr old    753 larva L3 puffstage 1-2    599 larva L3 puffstage 3-6    678 larva L3 puffstage 7-9  (1989) white prepupae new  (2899) white prepupae 12hr    595 white prepupae 24hr    337 pupae 2d postWPP    269 pupae 3d postWPP    325 pupae 4d postWPP    862 adult male 01day    468 adult male 05day    453 adult male 30day    450 adult female 01day    413 adult female 05day    381 adult female 30day    279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    446 embryo 02-04hr    367 embryo 04-06hr    205 embryo 06-08hr    172 embryo 08-10hr    493 embryo 10-12hr    1023 embryo 12-14hr    805 embryo 14-16hr    574 embryo 16-18hr    1611 embryo 18-20hr    4228 embryo 20-22hr    5028 embryo 22-24hr    6399 larva L1    1465 larva L2    728 larva L3 12hr old    753 larva L3 puffstage 1-2    599 larva L3 puffstage 3-6    678 larva L3 puffstage 7-9    1989 white prepupae new    2899 white prepupae 12hr    595 white prepupae 24hr    337 pupae 2d postWPP    269 pupae 3d postWPP    325 pupae 4d postWPP    862 adult male 01day    468 adult male 05day    453 adult male 30day    450 adult female 01day    413 adult female 05day    381 adult female 30day    279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    446 embryo 02-04hr    367 embryo 04-06hr    205 embryo 06-08hr    172 embryo 08-10hr    493 embryo 10-12hr    1023 embryo 12-14hr    805 embryo 14-16hr    574 embryo 16-18hr    1611 embryo 18-20hr    4228 embryo 20-22hr    5028 embryo 22-24hr    6399 larva L1    1465 larva L2    728 larva L3 12hr old    753 larva L3 puffstage 1-2    599 larva L3 puffstage 3-6    678 larva L3 puffstage 7-9    1989 white prepupae new    2899 white prepupae 12hr    595 white prepupae 24hr    337 pupae 2d postWPP    269 pupae 3d postWPP    325 pupae 4d postWPP    862 adult male 01day    468 adult male 05day    453 adult male 30day    450 adult female 01day    413 adult female 05day    381 adult female 30day    279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039467 expression level Developmental Stage   Expression Level embryo 00-02hr    446 embryo 02-04hr    367 embryo 04-06hr    205 embryo 06-08hr    172 embryo 08-10hr    493 embryo 10-12hr    1023 embryo 12-14hr    805 embryo 14-16hr    574 embryo 16-18hr    1611 embryo 18-20hr    4228 embryo 20-22hr    5028 embryo 22-24hr    6399 larva L1    1465 larva L2    728 larva L3 12hr old    753 larva L3 puffstage 1-2    599 larva L3 puffstage 3-6    678 larva L3 puffstage 7-9    1989 white prepupae new    2899 white prepupae 12hr    595 white prepupae 24hr    337 pupae 2d postWPP    269 pupae 3d postWPP    325 pupae 4d postWPP    862 adult male 01day    468 adult male 05day    453 adult male 30day    450 adult female 01day    413 adult female 05day    381 adult female 30day    279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (446) embryo 02-04hr  (367) embryo 04-06hr  (205) embryo 06-08hr  (172) embryo 08-10hr  (493) embryo 10-12hr  (1023) embryo 12-14hr  (805) embryo 14-16hr  (574) embryo 16-18hr  (1611) embryo 18-20hr  (4228) embryo 20-22hr  (5028) embryo 22-24hr  (6399) larva L1  (1465) larva L2  (728) larva L3 12hr old  (753) larva L3 puffstage 1-2  (599) larva L3 puffstage 3-6  (678) larva L3 puffstage 7-9  (1989) white prepupae new  (2899) white prepupae 12hr  (595) white prepupae 24hr  (337) pupae 2d postWPP  (269) pupae 3d postWPP  (325) pupae 4d postWPP  (862) adult male 01day  (468) adult male 05day  (453) adult male 30day  (450) adult female 01day  (413) adult female 05day  (381) adult female 30day  (279) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    446 embryo 02-04hr    367 embryo 04-06hr    205 embryo 06-08hr    172 embryo 08-10hr    493 embryo 10-12hr    1023 embryo 12-14hr    805 embryo 14-16hr    574 embryo 16-18hr  1611 embryo 18-20hr  (4228) embryo 20-22hr  (5028) embryo 22-24hr  (6399) larva L1  1465 larva L2    728 larva L3 12hr old    753 larva L3 puffstage 1-2    599 larva L3 puffstage 3-6    678 larva L3 puffstage 7-9  1989 white prepupae new  (2899) white prepupae 12hr    595 white prepupae 24hr    337 pupae 2d postWPP    269 pupae 3d postWPP    325 pupae 4d postWPP    862 adult male 01day    468 adult male 05day    453 adult male 30day    450 adult female 01day    413 adult female 05day    381 adult female 30day    279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    446 embryo 02-04hr    367 embryo 04-06hr    205 embryo 06-08hr    172 embryo 08-10hr    493 embryo 10-12hr    1023 embryo 12-14hr    805 embryo 14-16hr    574 embryo 16-18hr    1611 embryo 18-20hr    4228 embryo 20-22hr    5028 embryo 22-24hr    6399 larva L1    1465 larva L2    728 larva L3 12hr old    753 larva L3 puffstage 1-2    599 larva L3 puffstage 3-6    678 larva L3 puffstage 7-9    1989 white prepupae new    2899 white prepupae 12hr    595 white prepupae 24hr    337 pupae 2d postWPP    269 pupae 3d postWPP    325 pupae 4d postWPP    862 adult male 01day    468 adult male 05day    453 adult male 30day    450 adult female 01day    413 adult female 05day    381 adult female 30day    279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    446 embryo 02-04hr    367 embryo 04-06hr    205 embryo 06-08hr    172 embryo 08-10hr    493 embryo 10-12hr    1023 embryo 12-14hr    805 embryo 14-16hr    574 embryo 16-18hr    1611 embryo 18-20hr    4228 embryo 20-22hr    5028 embryo 22-24hr    6399 larva L1    1465 larva L2    728 larva L3 12hr old    753 larva L3 puffstage 1-2    599 larva L3 puffstage 3-6    678 larva L3 puffstage 7-9    1989 white prepupae new    2899 white prepupae 12hr    595 white prepupae 24hr    337 pupae 2d postWPP    269 pupae 3d postWPP    325 pupae 4d postWPP    862 adult male 01day    468 adult male 05day    453 adult male 30day    450 adult female 01day    413 adult female 05day    381 adult female 30day    279 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0039467    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0039467 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, adult hindgut, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0039467 expression level Tissue   Expression Level Larval Central Nervous System    35.475 Larval Midgut    27.5 Larval Hindgut    76.5 Larval Malpighian Tubules    19.5 Larval Fat Body    19.9 Larval Salivary Gland no informative data Larval Trachea    71.25 Larval Carcass    141 Adult Head    29.6 Adult Eye no informative data Adult Brain    26.2 Adult Thoracic-Abdominal Ganglion    32.4 Adult Crop    186 Adult Midgut no informative data Adult Hindgut    296.3 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    53.25 Adult VirginFemale Spermatheca    44.1 Adult InseminatedFemale Spermatheca    63.2 Adult Ovary    7.4 Adult Testis    12.6 Adult Male Accessory Gland    27 Adult Carcass    39.5 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    35.475 Larval Midgut    27.5 Larval Hindgut    76.5 Larval Malpighian Tubules    19.5 Larval Fat Body    19.9 Larval Salivary Gland no informative data Larval Trachea    71.25 Larval Carcass    141 Adult Head    29.6 Adult Eye no informative data Adult Brain    26.2 Adult Thoracic-Abdominal Ganglion    32.4 Adult Crop    186 Adult Midgut no informative data Adult Hindgut    296.3 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    53.25 Adult VirginFemale Spermatheca    44.1 Adult InseminatedFemale Spermatheca    63.2 Adult Ovary    7.4 Adult Testis    12.6 Adult Male Accessory Gland    27 Adult Carcass    39.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    35.475 Larval Midgut    27.5 Larval Hindgut    76.5 Larval Malpighian Tubules    19.5 Larval Fat Body    19.9 Larval Salivary Gland no informative data Larval Trachea    71.25 Larval Carcass    141 Adult Head    29.6 Adult Eye no informative data Adult Brain    26.2 Adult Thoracic-Abdominal Ganglion    32.4 Adult Crop    186 Adult Midgut no informative data Adult Hindgut    296.3 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    53.25 Adult VirginFemale Spermatheca    44.1 Adult InseminatedFemale Spermatheca    63.2 Adult Ovary    7.4 Adult Testis    12.6 Adult Male Accessory Gland    27 Adult Carcass    39.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    35.475 Larval Midgut    27.5 Larval Hindgut    76.5 Larval Malpighian Tubules    19.5 Larval Fat Body    19.9 Larval Salivary Gland no informative data Larval Trachea    71.25 Larval Carcass    141 Adult Head    29.6 Adult Eye no informative data Adult Brain    26.2 Adult Thoracic-Abdominal Ganglion    32.4 Adult Crop    186 Adult Midgut no informative data Adult Hindgut    296.3 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    53.25 Adult VirginFemale Spermatheca    44.1 Adult InseminatedFemale Spermatheca    63.2 Adult Ovary    7.4 Adult Testis    12.6 Adult Male Accessory Gland    27 Adult Carcass    39.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0039467 expression level Tissue   Expression Level Larval Central Nervous System    35.475 Larval Midgut    27.5 Larval Hindgut    76.5 Larval Malpighian Tubules    19.5 Larval Fat Body    19.9 Larval Salivary Gland no informative data Larval Trachea    71.25 Larval Carcass    141 Adult Head    29.6 Adult Eye no informative data Adult Brain    26.2 Adult Thoracic-Abdominal Ganglion    32.4 Adult Crop    186 Adult Midgut no informative data Adult Hindgut    296.3 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    53.25 Adult VirginFemale Spermatheca    44.1 Adult InseminatedFemale Spermatheca    63.2 Adult Ovary    7.4 Adult Testis    12.6 Adult Male Accessory Gland    27 Adult Carcass    39.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    35.475 Larval Midgut    27.5 Larval Hindgut    76.5 Larval Malpighian Tubules    19.5 Larval Fat Body    19.9 Larval Salivary Gland no informative data Larval Trachea    71.25 Larval Carcass    141 Adult Head    29.6 Adult Eye no informative data Adult Brain    26.2 Adult Thoracic-Abdominal Ganglion    32.4 Adult Crop    186 Adult Midgut no informative data Adult Hindgut    296.3 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    53.25 Adult VirginFemale Spermatheca    44.1 Adult InseminatedFemale Spermatheca    63.2 Adult Ovary    7.4 Adult Testis    12.6 Adult Male Accessory Gland    27 Adult Carcass    39.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    35.475 Larval Midgut    27.5 Larval Hindgut    76.5 Larval Malpighian Tubules    19.5 Larval Fat Body    19.9 Larval Salivary Gland no informative data Larval Trachea    71.25 Larval Carcass    141 Adult Head    29.6 Adult Eye no informative data Adult Brain    26.2 Adult Thoracic-Abdominal Ganglion    32.4 Adult Crop    186 Adult Midgut no informative data Adult Hindgut    296.3 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    53.25 Adult VirginFemale Spermatheca    44.1 Adult InseminatedFemale Spermatheca    63.2 Adult Ovary    7.4 Adult Testis    12.6 Adult Male Accessory Gland    27 Adult Carcass    39.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    35.475 Larval Midgut    27.5 Larval Hindgut    76.5 Larval Malpighian Tubules    19.5 Larval Fat Body    19.9 Larval Salivary Gland no informative data Larval Trachea    71.25 Larval Carcass    141 Adult Head    29.6 Adult Eye no informative data Adult Brain    26.2 Adult Thoracic-Abdominal Ganglion    32.4 Adult Crop    186 Adult Midgut no informative data Adult Hindgut    296.3 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    53.25 Adult VirginFemale Spermatheca    44.1 Adult InseminatedFemale Spermatheca    63.2 Adult Ovary    7.4 Adult Testis    12.6 Adult Male Accessory Gland    27 Adult Carcass    39.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland no informative data Larval Trachea     Larval Carcass     Adult Head     Adult Eye no informative data Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    29.6   NA  Eye    no informative data   NA  Brain    26.2   35.475  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    32.4   NA  Crop    186   27.5  Midgut    no informative data   76.5  Hindgut    296.3   19.5  Malpighian Tubules    no informative data   19.9  Fat Body    no informative data   no informative data  Salivary Gland    no informative data   NA  Heart    53.25   71.25  Trachea    NA   NA  VirginFemale Spermatheca    44.1   NA  InseminatedFemale Spermatheca    63.2   NA  Ovary    7.4   NA  Testis    12.6   NA  Male Accessory Gland    27   141  Carcass    39.5 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039467 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14253-RB FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG14253 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG14253GD313 Phenotype manifest in Allele
Classical Alleles ( 6 )
For All Classical Alleles Show
Allele of CG14253 Class Mutagen Stocks Known lesion CG14253c05546 piggyBac transposase 1 -- CG14253CB-6140-3 1 -- CG14253KG09313 P-element activity 1 -- CG14253NP6672 1 -- CG14253NP7467 1 -- CG14253c05604 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG14253 Class Mutagen Stocks Known lesion CG14253GD313 in vitro construct - RNAi in vitro construct - regulatory fusion 3 Yes CG14253KK105834 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6205 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD313} NA P{KK105834} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{RS3}CG14253CB-6140-3 NA P{SUPor-P}CG14253KG09313 NA PBac{PB}CG14253c05546 NA PBac{PB}CG14253c05604 NA insertion of enhancer trap binary system P{GawB}CG14253NP6672 No P{GawB}CG14253NP7467 No
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG14253 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68133 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039467 DroID - A comprehensive database of gene and protein interactions. • FBgn0039467 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43243
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23264 Dere\GG11516 Dgri\GH18627 Dmoj\GI24298 Dper\GL23892 Dpse\GA27090 Dsec\GM10356 Dsim\GD21318 Dvir\GJ23076 Dwil\GK11380 Dyak\GE23704
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AGAP001392-PA Anopheles gambiae (mosquito) XP_973944.1 Tribolium castaneum (red flour beetle) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV25619 ISCW007895 ISCW007894 ISCW001926 FBgn0240862 FBgn0213391 FBgn0210178 FBgn0192755 FBgn0165306 FBgn0248461 FBgn0243900 FBgn0161482 FBgn0147021 FBgn0126094 FBgn0103813 FBgn0100258 AGAP001392 AAEL004569 GLEAN_09579
Stocks & Reagents
Stocks Listed in FlyBase ( 9 )
Bloomington	16479 y1; ry506 P{SUPor-P}CG14253KG09313/TM3, Sb1 Ser1
Harvard	- PBac{PB}CG14253c05546
Kyoto	123944 w1118; P{RS3}CG14253CB-6140-3 114297 w*; P{GawB}CG14253NP7467 / TM6, P{UAS-lacZ.UW23-1}UW23-1 105318 y* w*; P{GawB}CG14253NP6672 / TM6, P{UAS-lacZ.UW23-1}UW23-1
VDRC	v107256 P{KK105834}VIE-260B v49909 w1118; P{GD313}v49909 v49908 w1118; P{GD313}v49908/TM3 v52635 w1118; P{GD313}v52635/CyO
Genomic Clones ( 1 )
	BACR05C10 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 45 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE60306 RE68347
Other clones	DPiM_RE68347
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH11111 GH13315 LP07108 LP10021 RE22856 RE44361 RE51736 RE51806 RE55950 RE60916 RE69446 SD11971 SD22131 SD26178 SD26926
Other clones	31281 46631 60537 74916 99073 125278 214223.11 571429 CK01.2A.H6 CK01.2A.H8 EC26037 EC27701 EK140452 EK165306 EK165464 EK204944 EK221544 EK247545 EN16845 FGH104H06 FGM229E11 IP04459 IP04759 LD23985 RP003540467 RP003660774 RP003670596
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039467 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43243
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143260 NM_170300 NM_170301 NM_170302 NM_170303 RefSeq (Proteins) • NP_651517 NP_733179 NP_733180 NP_733181 NP_733182 DDBJ / EMBL / GenBank • AAF56645 AAL49260 AAN14099 AAN14100 AAN14101 AAN14102 AY071638 BI485075 CL528250 CZ470086 CZ470129 Entrez Gene - A searchable database of RefSeq genes. • 43243 UniProtKB/TrEMBL • Q8SYC5 Q9VB97
Other Crossreferences
Linkouts
	BioGRID - A database of protein and genetic interactions • 68133 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039467 DroID - A comprehensive database of gene and protein interactions. • FBgn0039467 DRSC - Results from RNAi screens. • FBgn0039467 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039467 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14253-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039467 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43243 InParanoid A subset of ortholog calls from InParanoid. • AGAP001392-PA Anopheles gambiae (mosquito) XP_973944.1 Tribolium castaneum (red flour beetle) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43243 modMine - Data generated by the modENCODE project. • FBgn0039467 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV25619 ISCW007895 ISCW007894 ISCW001926 FBgn0240862 FBgn0213391 FBgn0210178 FBgn0192755 FBgn0165306 FBgn0248461 FBgn0243900 FBgn0161482 FBgn0147021 FBgn0126094 FBgn0103813 FBgn0100258 AGAP001392 AAEL004569 GLEAN_09579
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG14253 (Wertheim et al., 2011, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 13 )
Research paper	Wertheim et al., 2011, Mol. Ecol. 20(5): 932--949 Functional genomics of the evolution of increased resistance to parasitism in Drosophila. [FBrf0213049] Asha et al., 2003, Genetics 163(1): 203--215 Analysis of ras-induced overproliferation in Drosophila hemocytes. [FBrf0155813]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]