Gene model reviewed during 5.47
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\NSD using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\NSD in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Renamed from 'Mes-4' to 'NSD' because: i) the 'Mes-4' symbol was too easily confused with the unrelated gene 'Mes4' (FBgn0034726); ii) the original 'Mes-4' symbol was assigned based only on an ADRC abstract (FBrf0145882); iii) FBrf0201596 and FBrf0178951 say that this gene shows homology to human and mouse NSD1, WHSC1 (aka NSD2) and WHSC1-L (NSD3); iv) FBrf0225639 uses 'NSD' as a synonym of 'Mes-4'.
Gene expression is increased in response to the presence of two copies of Scer\GAL4hs.PB.
One of 42 Drosophila genes identified as being most likely to reveal molecular and cellular mechanisms of nervous system development or plasticity relevant to human Mental Retardation disorders.