FlyBase Gene Report: Dmel\mfrn

General Information

Symbol

Dmel\mfrn

Species

D. melanogaster

Name

mitoferrin

Annotation Symbol

CG4963

Feature Type

protein_coding_gene

FlyBase ID

FBgn0039561

Gene Model Status

Current

Stock Availability

8 publicly available

Gene Snapshot

Contributions welcome

Other Summaries

Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Also Known As

dmfrn

Key Links

Genomic Location

Cytogenetic map

98B6-98B6

Sequence location

3R:27,942,796..27,948,021 [-]

Recombination map

3-94

RefSeq locus

NT_033777 REGION:27942796..27948021

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (6 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables iron ion transmembrane transporter activity

inferred from direct assay

(assigned by UniProt )

(Metzendorf et al., 2009)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables iron ion transmembrane transporter activity

inferred from biological aspect of ancestor with PANTHER:PTN000641807

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (3 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

involved_in iron import into the mitochondrion

inferred from direct assay

(assigned by UniProt )

(Metzendorf et al., 2009)

involved_in multicellular organismal iron ion homeostasis

inferred from mutant phenotype

(Navarro et al., 2015)

involved_in spermatid differentiation

inferred from mutant phenotype

(Metzendorf and Lind, 2010)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in iron import into the mitochondrion

inferred from biological aspect of ancestor with PANTHER:PTN000641807

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

located_in mitochondrial inner membrane

inferred from direct assay

(assigned by UniProt )

(Metzendorf et al., 2009)

located_in mitochondrion

inferred from direct assay

(Metzendorf et al., 2009)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

SLC25 FAMILY OF MITOCHONDRIAL TRANSPORTERS

Protein Family (UniProt)

Belongs to the mitochondrial carrier (TC 2.A.29) family. (Q9VAY3)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

SLC25 FAMILY OF MITOCHONDRIAL TRANSPORTERS -: The solute carrier family 25 (SLC25) or mitochondrial carrier family (MCF) members shuttle metabolites, nucleotides and cofactors across the inner mitochondrial membrane. (Adapted from FBrf0212481, FBrf0212949 and PMID:23266187).

Protein Function (UniProtKB)

Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly.

(UniProt, Q9VAY3)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\mfrn for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.47

Low-frequency RNA-Seq exon junction(s) not annotated.

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

mfrn-RA

FBtr0085266

NM_143343

3037

379

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

mfrn-PA

FBpp0084635

41.8

379

8.96

NP_651600

AAF56764

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VAY3

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mfrn using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

mfrn_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | ubiquitous

(Fisher et al., 2012)

RT-PCR

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | male & day 3 of adulthood

adult head

(Metzendorf and Lind, 2010)

adult thorax

(Metzendorf and Lind, 2010)

testis

(Metzendorf and Lind, 2010)

adult Malpighian tubule

(Metzendorf and Lind, 2010)

adult gut

(Metzendorf and Lind, 2010)

Additional Descriptive Data

mfrn is expressed at similar levels to whole fly in all tissues tested except testis where it is 2-fold higher. This is in contast to Fly Atlas which shows the lowest levels in testis.

(Metzendorf and Lind, 2010)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in mitochondrial inner membrane

inferred from direct assay

(assigned by UniProt )

(Metzendorf et al., 2009)

located_in mitochondrion

inferred from direct assay

(Metzendorf et al., 2009)

Expression Deduced from Reporters

Reporter: P{lacW}mfrn^SH115

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | male

spermatid

(Metzendorf and Lind, 2010)

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\mfrn in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\mfrn

View exonic expression by tissue for Dmel\mfrn

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0039561

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0039561

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG4963-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG4963

Flygut - An atlas of the Drosophila adult midgut

FBgn0039561

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 7 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 8 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of mfrn

Transgenic constructs containing regulatory region of mfrn

Deletions and Duplications ( 1 )

Disrupted in

Df(3R)ED6277

(Metzendorf and Lind, 2010)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

partially lethal - majority die, with Scer\GAL4^pnr-MD237

mfrn^GD336

viable

mfrn^EY01302

viable, with Scer\GAL4^Mef2.PR

mfrn^GD336

viable, with Scer\GAL4^tin.CΔ4

mfrn^GD336

Sterility

Allele

female fertile

mfrn^SH115

fertile

mfrn^EY01302

male sterile (with Df(3R)ED6277)

male sterile (with mfrn^Df13)

mfrn^SH115

male sterile (with mfrn^SH115)

mfrn^Df13

male sterile | recessive

mfrn^SH115

Other Phenotypes

Allele

chemical sensitive, with Scer\GAL4^Act5C.PU

some die during pupal stage, with Scer\GAL4^pnr-MD237

mfrn^GD336

Phenotype manifest in

Allele

elongation stage spermatid

mfrn^SH115

mitochondrial derivative

mfrn^SH115

spermatid cyst

mfrn^SH115

spermatozoon

mfrn^SH115

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (4)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\SLC25A37

14 of 15

Yes

Hsap\SLC25A28

12 of 15

Yes

Hsap\NARS2

1 of 15

Hsap\NARS

1 of 15

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (4)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Slc25a28

12 of 15

Yes

Mmus\Gm16867

8 of 15

Yes

Mmus\Slc25a37

8 of 15

Yes

Mmus\Nars

1 of 15

Rattus norvegicus (Norway rat) (4)

Rnor\Slc25a37

12 of 13

Yes

Rnor\Slc25a28

11 of 13

Yes

Rnor\Nars2

1 of 13

Rnor\Nars

1 of 13

Xenopus tropicalis (Western clawed frog) (4)

Xtro\slc25a37

12 of 12

Yes

Xtro\slc25a28

11 of 12

Yes

Xtro\nars2

1 of 12

Xtro\nars

1 of 12

Danio rerio (Zebrafish) (4)

Drer\slc25a37

13 of 15

Yes

Drer\slc25a28

12 of 15

Yes

Drer\nars2

1 of 15

Drer\nars

1 of 15

Caenorhabditis elegans (Nematode, roundworm) (3)

Cele\mfn-1

14 of 15

Yes

Cele\nars-1

1 of 15

Cele\nars-2

1 of 15

Arabidopsis thaliana (thale-cress) (8)

Atha\AT1G07030

9 of 9

Yes

Atha\AT2G30160

9 of 9

Yes

Atha\AT1G07025

1 of 9

Yes

Atha\AT1G68420

1 of 9

Yes

1 of 9

1 of 9

1 of 9

1 of 9

Saccharomyces cerevisiae (Brewer's yeast) (2)

Scer\MRS3

14 of 15

Yes

Scer\MRS4

13 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\SPAC8C9.12c

11 of 12

Yes

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190ANQ )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA18557

Drosophila persimilis

Dper\GL23880

Drosophila willistoni

Dwil\GK22532

Drosophila virilis

Dvir\GJ10770

Drosophila mojavensis

Dmoj\GI23269

Drosophila grimshawi

Dgri\GH19165

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091506KM )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17018383

Glossina morsitans

Tsetse fly

Gmor\GMOY006251

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_12816

Mayetiola destructor

Hessian fly

Mdes\Mdes001327

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL006564

Anopheles darlingi

American malaria mosquito

Adar\ADAC005669

Anopheles gambiae

Malaria mosquito

Agam\AGAP006030

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ010585

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0G2A )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA002266

Danaus plexippus

Monarch butterfly

Dple\DPOGS208219-PA

Danaus plexippus

Monarch butterfly

Dple\DPOGS208218-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL008688

Apis florea

Little honeybee

Aflo\3074462996

Apis mellifera

Western honey bee

Amel\mfrn

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP14631

Bombus terrestris

Buff-tailed bumblebee

Bter\15202627

Linepithema humile

Argentine ant

Lhum\LH16675

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:0014e7

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG006439

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_01645

Tribolium castaneum

Red flour beetle

Tcas\TC012585

Pediculus humanus

Human body louse

Phum\PHUM027020

Pediculus humanus

Human body louse

Phum\PHUM204560

Pediculus humanus

Human body louse

Phum\PHUM204920

Rhodnius prolixus

Kissing bug

Rpro\RPRC002819

Cimex lectularius

Bed bug

Clec\CLEC009495

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI001051

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_18365

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0G2M )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR004049

Ixodes scapularis

Black-legged tick

Isca\ISCW018156

Stegodyphus mimosarum

African social velvet spider

Smim\KFM78170.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur33g00240

Tetranychus urticae

Two-spotted spider mite

Turt\tetur33g00250

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_197988

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_197963

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0PU8 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Slc25a28

Ciona intestinalis

Vase tunicate

Cint\LOC100181034

Gallus gallus

Domestic chicken

Ggal\SLC25A28

Gallus gallus

Domestic chicken

Ggal\SLC25A37

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (45)

Gene Symbol

Score

Source

Alignment

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

GC1

1 of 10

GC2

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

sea

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 3 )

Allele

Disease

Interaction

References

mfrn^GD336

ameliorates Friedreich ataxia

modeled by fh^{dsRNA.UAS.cLa}

(Navarro et al., 2015)

mfrn^NIG.4963R

ameliorates Friedreich ataxia

modeled by fh^{dsRNA.UAS.cLa}

(Navarro et al., 2015)

mfrn^UAS.cNa

exacerbates Friedreich ataxia

modeled by fh^{dsRNA.UAS.cLa}

(Navarro et al., 2015)

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

SLC25A37; solute carrier family 25 member 37

14 of 15

610387

SLC25A28; solute carrier family 25 member 28

12 of 15

609767

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

mfrn - Drep2

anti tag coimmunoprecipitation, peptide massfingerprinting

(Andlauer et al., 2014)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

mfrn

(Edenharter et al., 2017, Navarro et al., 2015)

enhanceable

mfrn

(Navarro et al., 2015)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

68234

DroID - A comprehensive database of gene and protein interactions.

FBgn0039561

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

43353

MIST (genetic) - An integrated Molecular Interaction Database

mfrn

MIST (protein-protein) - An integrated Molecular Interaction Database

mfrn

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-94

Cytogenetic map

98B6-98B6

Sequence location

3R:27,942,796..27,948,021 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

98B6-98B6

Limits computationally determined from genome sequence between P{PZ}btz^rL203 and P{PZ}l(3)06487⁰⁶⁴⁸⁷

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-94

(FlyBase, 2016)

3-92.4

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (8)

Bloomington

12489

w¹¹¹⁸; P{GT1}mfrn^BG00456

19811

y¹ w^67c23; P{EPgy2}mfrn^EY01302

34038

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01013}attP2

59729

y¹ w^*; Mi{MIC}mfrn^MI14836/TM3, Sb¹ Ser¹

FlyORF

F003035

M{UAS-mfrn.ORF.3xHA.GW}ZH-86Fb

Kyoto

105489

y^* w^*; P{GawB}mfrn^NP7499 / TM6, P{UAS-lacZ.UW23-1}UW23-1

VDRC

v100597

P{KK108379}VIE-260B

v12342

w¹¹¹⁸; P{GD336}v12342/TM3

Genomic Clones (7)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (204)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

GH09840

Other clones

DPiM_GH09840

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0039561

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

AT02361
AT02667
AT03607
AT05664
AT06694
AT08033
AT08242
AT08926
AT08995
AT09688
AT09747
AT09771
AT10356
AT10377
AT11020
AT11137
AT11372
AT11872
AT12467
AT12656
AT13791
AT14879
AT15055
AT15565
AT16520
AT16714
AT17501
AT19470
AT20163
AT20186
AT20678
AT22704
AT23103
AT25721
AT26457
AT26762
AT26850
AT27056
AT27080
AT28168
AT28630
AT29001
AT29151
AT31390
GH04641
GH10959
GH16718
HL04954
LD13719
LP12922
RE09581
SD19471
SD19522
SD23452

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0039561

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

43353

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: mfrn CG4963

(Metzendorf et al., 2009)

Source for database merge of

Source for merge of: CG4963 anon- EST:fe2H5

(FlyBase, 1996-)

Additional comments

Source for merge of CG4963 anon- EST:fe2H5 was sequence comparison ( date:000605 ).

(FlyBase, 1996-)

Other Comments

Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days.

(Claridge-Chang et al., 2001)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 39 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

43353

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9VAY3

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0039561

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0039561

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

mfrn_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG4963

Flygut - An atlas of the Drosophila adult midgut

FBgn0039561

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

43353

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG4963

modMine - A data warehouse for the modENCODE project

FBgn0039561

Linkouts

BioGRID - A database of protein and genetic interactions.

68234

DPiM - Drosophila Protein interaction map

FBgn0039561

DroID - A comprehensive database of gene and protein interactions.

FBgn0039561

DRSC - Results frm RNAi screens

FBgn0039561

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0039561

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG4963-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0039561

FlyMine - An integrated database for Drosophila genomics

FBgn0039561

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

43353

MIST (genetic) - An integrated Molecular Interaction Database

mfrn

MIST (protein-protein) - An integrated Molecular Interaction Database

mfrn

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

CG4963

(Curcio et al., 2020, Andlauer et al., 2014, Ashwal-Fluss et al., 2014, Tang and Zhou, 2013, Japanese National Institute of Genetics, 2012.5.21, Mandilaras and Missirlis, 2012, Maynard et al., 2010, Metzendorf and Lind, 2010, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Metzendorf et al., 2009, Zhou et al., 2008, Staudt et al., 2005)

HD35059

(Staudt et al., 2005)

Mfrn

(Mandilaras and Missirlis, 2012)

anon-EST:fe2H5

dmfrn

(Curcio et al., 2020, Wan et al., 2020, Lopez et al., 2016, Navarro et al., 2015, Tang and Zhou, 2013, Metzendorf and Lind, 2010, Metzendorf et al., 2009)

mfrn

(Kanellopoulos et al., 2020, Zarubin et al., 2020, Calap-Quintana et al., 2018, Monnier et al., 2018, Calap-Quintana et al., 2017, Andlauer et al., 2014, Luck et al., 2014, Mandilaras et al., 2013, Shulman et al., 2011, White et al., 2011)

Name Synonyms

CG4963

Mitoferrin

(Curcio et al., 2020, Andlauer et al., 2014, Fabian and Brill, 2012, Mandilaras and Missirlis, 2012)

anon-fast-evolving-2H5

mitoferrin

(Navarro et al., 2015, Mandilaras et al., 2013, Metzendorf and Lind, 2010, Metzendorf et al., 2009)

Secondary FlyBase IDs

FBgn0025206

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (59)

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