Gene Dmel\CG1523

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General Information

Symbol

Dmel\CG1523

Species

D. melanogaster

Name

Annotation symbol

CG1523

Feature type

protein_coding_gene

FlyBase ID

FBgn0039601

Gene Model Status

Current

Stock availability

5 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

98E5-98E5

Sequence location

3R:24,643,064..24,645,390 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG1523 (FBgn0039601). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1631466_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG1523. Gene sequence location is 3R:24643064..24645390.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

98E5-98E5

Limits computationally determined from genome sequence between P{PZ}l(3)06487⁰⁶⁴⁸⁷ and P{EP}EP3390^EP3390

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG1523 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.48

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG1523-RA

FBtr0085355

NM_143378

2150

621

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG1523-PA

FBpp0084724

69.6

621

7.77

NP_651635

AAF56817

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

WD40 repeat (IPR001680)

WD40-repeat-containing domain (IPR017986)

WD40/YVTN repeat-like-containing domain (IPR015943)

WD40 repeat, conserved site (IPR019775)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VAT2

UniProtKB/TrEMBL

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

(Fisher et al., 2012)

Comment:maternally deposited

embryonic stage 4 -- 6

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | faint & ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | faint & ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | faint & ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | faint & ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		177.1
Larval Midgut		128.9
Larval Hindgut		120.7
Larval Malpighian Tubules		134.7
Larval Fat Body		114.9
Larval Salivary Gland		205.4
Larval Trachea		142.3
Larval Carcass		136.1
Adult Head		105.8
Adult Eye		122.475
Adult Brain		131.5
Adult Thoracic-Abdominal Ganglion		120.8
Adult Crop		162.4
Adult Midgut		114.8
Adult Hindgut		108.6
Adult Malpighian Tubules		134.7
Adult Fat Body		86.3
Adult Salivary Gland		197.5
Adult Heart		94.125
Adult VirginFemale Spermatheca		118.6
Adult InseminatedFemale Spermatheca		140
Adult Ovary		190.3
Adult Testis		66.8
Adult Male Accessory Gland		152.7
Adult Carcass		135.2
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		177.1
Larval Midgut		128.9
Larval Hindgut		120.7
Larval Malpighian Tubules		134.7
Larval Fat Body		114.9
Larval Salivary Gland		205.4
Larval Trachea		142.3
Larval Carcass		136.1
Adult Head		105.8
Adult Eye		122.475
Adult Brain		131.5
Adult Thoracic-Abdominal Ganglion		120.8
Adult Crop		162.4
Adult Midgut		114.8
Adult Hindgut		108.6
Adult Malpighian Tubules		134.7
Adult Fat Body		86.3
Adult Salivary Gland		197.5
Adult Heart		94.125
Adult VirginFemale Spermatheca		118.6
Adult InseminatedFemale Spermatheca		140
Adult Ovary		190.3
Adult Testis		66.8
Adult Male Accessory Gland		152.7
Adult Carcass		135.2
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		177.1
Larval Midgut		128.9
Larval Hindgut		120.7
Larval Malpighian Tubules		134.7
Larval Fat Body		114.9
Larval Salivary Gland		205.4
Larval Trachea		142.3
Larval Carcass		136.1
Adult Head		105.8
Adult Eye		122.475
Adult Brain		131.5
Adult Thoracic-Abdominal Ganglion		120.8
Adult Crop		162.4
Adult Midgut		114.8
Adult Hindgut		108.6
Adult Malpighian Tubules		134.7
Adult Fat Body		86.3
Adult Salivary Gland		197.5
Adult Heart		94.125
Adult VirginFemale Spermatheca		118.6
Adult InseminatedFemale Spermatheca		140
Adult Ovary		190.3
Adult Testis		66.8
Adult Male Accessory Gland		152.7
Adult Carcass		135.2
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		177.1
Larval Midgut		128.9
Larval Hindgut		120.7
Larval Malpighian Tubules		134.7
Larval Fat Body		114.9
Larval Salivary Gland		205.4
Larval Trachea		142.3
Larval Carcass		136.1
Adult Head		105.8
Adult Eye		122.475
Adult Brain		131.5
Adult Thoracic-Abdominal Ganglion		120.8
Adult Crop		162.4
Adult Midgut		114.8
Adult Hindgut		108.6
Adult Malpighian Tubules		134.7
Adult Fat Body		86.3
Adult Salivary Gland		197.5
Adult Heart		94.125
Adult VirginFemale Spermatheca		118.6
Adult InseminatedFemale Spermatheca		140
Adult Ovary		190.3
Adult Testis		66.8
Adult Male Accessory Gland		152.7
Adult Carcass		135.2
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		177.1
Larval Midgut		128.9
Larval Hindgut		120.7
Larval Malpighian Tubules		134.7
Larval Fat Body		114.9
Larval Salivary Gland		205.4
Larval Trachea		142.3
Larval Carcass		136.1
Adult Head		105.8
Adult Eye		122.475
Adult Brain		131.5
Adult Thoracic-Abdominal Ganglion		120.8
Adult Crop		162.4
Adult Midgut		114.8
Adult Hindgut		108.6
Adult Malpighian Tubules		134.7
Adult Fat Body		86.3
Adult Salivary Gland		197.5
Adult Heart		94.125
Adult VirginFemale Spermatheca		118.6
Adult InseminatedFemale Spermatheca		140
Adult Ovary		190.3
Adult Testis		66.8
Adult Male Accessory Gland		152.7
Adult Carcass		135.2
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		177.1
Larval Midgut		128.9
Larval Hindgut		120.7
Larval Malpighian Tubules		134.7
Larval Fat Body		114.9
Larval Salivary Gland		205.4
Larval Trachea		142.3
Larval Carcass		136.1
Adult Head		105.8
Adult Eye		122.475
Adult Brain		131.5
Adult Thoracic-Abdominal Ganglion		120.8
Adult Crop		162.4
Adult Midgut		114.8
Adult Hindgut		108.6
Adult Malpighian Tubules		134.7
Adult Fat Body		86.3
Adult Salivary Gland		197.5
Adult Heart		94.125
Adult VirginFemale Spermatheca		118.6
Adult InseminatedFemale Spermatheca		140
Adult Ovary		190.3
Adult Testis		66.8
Adult Male Accessory Gland		152.7
Adult Carcass		135.2
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		177.1
Larval Midgut		128.9
Larval Hindgut		120.7
Larval Malpighian Tubules		134.7
Larval Fat Body		114.9
Larval Salivary Gland		205.4
Larval Trachea		142.3
Larval Carcass		136.1
Adult Head		105.8
Adult Eye		122.475
Adult Brain		131.5
Adult Thoracic-Abdominal Ganglion		120.8
Adult Crop		162.4
Adult Midgut		114.8
Adult Hindgut		108.6
Adult Malpighian Tubules		134.7
Adult Fat Body		86.3
Adult Salivary Gland		197.5
Adult Heart		94.125
Adult VirginFemale Spermatheca		118.6
Adult InseminatedFemale Spermatheca		140
Adult Ovary		190.3
Adult Testis		66.8
Adult Male Accessory Gland		152.7
Adult Carcass		135.2
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		177.1
Larval Midgut		128.9
Larval Hindgut		120.7
Larval Malpighian Tubules		134.7
Larval Fat Body		114.9
Larval Salivary Gland		205.4
Larval Trachea		142.3
Larval Carcass		136.1
Adult Head		105.8
Adult Eye		122.475
Adult Brain		131.5
Adult Thoracic-Abdominal Ganglion		120.8
Adult Crop		162.4
Adult Midgut		114.8
Adult Hindgut		108.6
Adult Malpighian Tubules		134.7
Adult Fat Body		86.3
Adult Salivary Gland		197.5
Adult Heart		94.125
Adult VirginFemale Spermatheca		118.6
Adult InseminatedFemale Spermatheca		140
Adult Ovary		190.3
Adult Testis		66.8
Adult Male Accessory Gland		152.7
Adult Carcass		135.2
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	105.8
NA	Eye	122.475
NA	Brain	131.5
177.1	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	120.8
NA	Crop	162.4
128.9	Midgut	114.8
120.7	Hindgut	108.6
134.7	Malpighian Tubules	134.7
114.9	Fat Body	86.3
205.4	Salivary Gland	197.5
NA	Heart	94.125
142.3	Trachea	NA
NA	VirginFemale Spermatheca	118.6
NA	InseminatedFemale Spermatheca	140
NA	Ovary	190.3
NA	Testis	66.8
NA	Male Accessory Gland	152.7
136.1	Carcass	135.2

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		18
central nervous system, pupae P8		9
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		6
head, mated 1-day female		7
head, mated 4-day female		5
head, mated 20-day female		6
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		6
digestive system, 4-day adult		6
digestive system, 20-day adult		8
fat body, larvae L3 wandering		3
fat body, white prepupae		8
fat body, pupae P8		12
carcass, larvae L3 wandering		12
carcass, 1-day adult		5
carcass, 4-day adult		6
carcass, 20-day adult		7
ovary, virgin 4-day female		21
ovary, mated 4-day female		21
testis, mated 4-day male		11
accessory gland, mated 4-day male		8
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		18
central nervous system, pupae P8		9
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		6
head, mated 1-day female		7
head, mated 4-day female		5
head, mated 20-day female		6
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		6
digestive system, 4-day adult		6
digestive system, 20-day adult		8
fat body, larvae L3 wandering		3
fat body, white prepupae		8
fat body, pupae P8		12
carcass, larvae L3 wandering		12
carcass, 1-day adult		5
carcass, 4-day adult		6
carcass, 20-day adult		7
ovary, virgin 4-day female		21
ovary, mated 4-day female		21
testis, mated 4-day male		11
accessory gland, mated 4-day male		8
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		18
central nervous system, pupae P8		9
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		6
head, mated 1-day female		7
head, mated 4-day female		5
head, mated 20-day female		6
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		6
digestive system, 4-day adult		6
digestive system, 20-day adult		8
fat body, larvae L3 wandering		3
fat body, white prepupae		8
fat body, pupae P8		12
carcass, larvae L3 wandering		12
carcass, 1-day adult		5
carcass, 4-day adult		6
carcass, 20-day adult		7
ovary, virgin 4-day female		21
ovary, mated 4-day female		21
testis, mated 4-day male		11
accessory gland, mated 4-day male		8
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		18
central nervous system, pupae P8		9
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		6
head, mated 1-day female		7
head, mated 4-day female		5
head, mated 20-day female		6
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		6
digestive system, 4-day adult		6
digestive system, 20-day adult		8
fat body, larvae L3 wandering		3
fat body, white prepupae		8
fat body, pupae P8		12
carcass, larvae L3 wandering		12
carcass, 1-day adult		5
carcass, 4-day adult		6
carcass, 20-day adult		7
ovary, virgin 4-day female		21
ovary, mated 4-day female		21
testis, mated 4-day male		11
accessory gland, mated 4-day male		8
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		18
central nervous system, pupae P8		9
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		6
head, mated 1-day female		7
head, mated 4-day female		5
head, mated 20-day female		6
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		6
digestive system, 4-day adult		6
digestive system, 20-day adult		8
fat body, larvae L3 wandering		3
fat body, white prepupae		8
fat body, pupae P8		12
carcass, larvae L3 wandering		12
carcass, 1-day adult		5
carcass, 4-day adult		6
carcass, 20-day adult		7
ovary, virgin 4-day female		21
ovary, mated 4-day female		21
testis, mated 4-day male		11
accessory gland, mated 4-day male		8
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		18
central nervous system, pupae P8		9
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		6
head, mated 1-day female		7
head, mated 4-day female		5
head, mated 20-day female		6
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		6
digestive system, 4-day adult		6
digestive system, 20-day adult		8
fat body, larvae L3 wandering		3
fat body, white prepupae		8
fat body, pupae P8		12
carcass, larvae L3 wandering		12
carcass, 1-day adult		5
carcass, 4-day adult		6
carcass, 20-day adult		7
ovary, virgin 4-day female		21
ovary, mated 4-day female		21
testis, mated 4-day male		11
accessory gland, mated 4-day male		8
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		18
central nervous system, pupae P8		9
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		6
head, mated 1-day female		7
head, mated 4-day female		5
head, mated 20-day female		6
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		6
digestive system, 4-day adult		6
digestive system, 20-day adult		8
fat body, larvae L3 wandering		3
fat body, white prepupae		8
fat body, pupae P8		12
carcass, larvae L3 wandering		12
carcass, 1-day adult		5
carcass, 4-day adult		6
carcass, 20-day adult		7
ovary, virgin 4-day female		21
ovary, mated 4-day female		21
testis, mated 4-day male		11
accessory gland, mated 4-day male		8
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		18
central nervous system, pupae P8		9
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		6
head, mated 1-day female		7
head, mated 4-day female		5
head, mated 20-day female		6
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		6
digestive system, 4-day adult		6
digestive system, 20-day adult		8
fat body, larvae L3 wandering		3
fat body, white prepupae		8
fat body, pupae P8		12
carcass, larvae L3 wandering		12
carcass, 1-day adult		5
carcass, 4-day adult		6
carcass, 20-day adult		7
ovary, virgin 4-day female		21
ovary, mated 4-day female		21
testis, mated 4-day male		11
accessory gland, mated 4-day male		8
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		43
embryo 02-04hr		55
embryo 04-06hr		38
embryo 06-08hr		38
embryo 08-10hr		38
embryo 10-12hr		35
embryo 12-14hr		22
embryo 14-16hr		25
embryo 16-18hr		17
embryo 18-20hr		11
embryo 20-22hr		15
embryo 22-24hr		13
larva L1		10
larva L2		9
larva L3 12hr old		9
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		14
white prepupae new		15
white prepupae 12hr		18
white prepupae 24hr		20
pupae 2d postWPP		18
pupae 3d postWPP		10
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		11
adult male 30day		12
adult female 01day		17
adult female 05day		21
adult female 30day		24
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(43)
embryo 02-04hr		(55)
embryo 04-06hr		(38)
embryo 06-08hr		(38)
embryo 08-10hr		(38)
embryo 10-12hr		(35)
embryo 12-14hr		22
embryo 14-16hr		25
embryo 16-18hr		17
embryo 18-20hr		11
embryo 20-22hr		15
embryo 22-24hr		13
larva L1		10
larva L2		9
larva L3 12hr old		9
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		14
white prepupae new		15
white prepupae 12hr		18
white prepupae 24hr		20
pupae 2d postWPP		18
pupae 3d postWPP		10
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		11
adult male 30day		12
adult female 01day		17
adult female 05day		21
adult female 30day		24
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		43
embryo 02-04hr		55
embryo 04-06hr		38
embryo 06-08hr		38
embryo 08-10hr		38
embryo 10-12hr		35
embryo 12-14hr		22
embryo 14-16hr		25
embryo 16-18hr		17
embryo 18-20hr		11
embryo 20-22hr		15
embryo 22-24hr		13
larva L1		10
larva L2		9
larva L3 12hr old		9
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		14
white prepupae new		15
white prepupae 12hr		18
white prepupae 24hr		20
pupae 2d postWPP		18
pupae 3d postWPP		10
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		11
adult male 30day		12
adult female 01day		17
adult female 05day		21
adult female 30day		24
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		43
embryo 02-04hr		55
embryo 04-06hr		38
embryo 06-08hr		38
embryo 08-10hr		38
embryo 10-12hr		35
embryo 12-14hr		22
embryo 14-16hr		25
embryo 16-18hr		17
embryo 18-20hr		11
embryo 20-22hr		15
embryo 22-24hr		13
larva L1		10
larva L2		9
larva L3 12hr old		9
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		14
white prepupae new		15
white prepupae 12hr		18
white prepupae 24hr		20
pupae 2d postWPP		18
pupae 3d postWPP		10
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		11
adult male 30day		12
adult female 01day		17
adult female 05day		21
adult female 30day		24
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		43
embryo 02-04hr		55
embryo 04-06hr		38
embryo 06-08hr		38
embryo 08-10hr		38
embryo 10-12hr		35
embryo 12-14hr		22
embryo 14-16hr		25
embryo 16-18hr		17
embryo 18-20hr		11
embryo 20-22hr		15
embryo 22-24hr		13
larva L1		10
larva L2		9
larva L3 12hr old		9
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		14
white prepupae new		15
white prepupae 12hr		18
white prepupae 24hr		20
pupae 2d postWPP		18
pupae 3d postWPP		10
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		11
adult male 30day		12
adult female 01day		17
adult female 05day		21
adult female 30day		24
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(43)
embryo 02-04hr		(55)
embryo 04-06hr		(38)
embryo 06-08hr		(38)
embryo 08-10hr		(38)
embryo 10-12hr		(35)
embryo 12-14hr		22
embryo 14-16hr		25
embryo 16-18hr		17
embryo 18-20hr		11
embryo 20-22hr		15
embryo 22-24hr		13
larva L1		10
larva L2		9
larva L3 12hr old		9
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		14
white prepupae new		15
white prepupae 12hr		18
white prepupae 24hr		20
pupae 2d postWPP		18
pupae 3d postWPP		10
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		11
adult male 30day		12
adult female 01day		17
adult female 05day		21
adult female 30day		24
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		43
embryo 02-04hr		55
embryo 04-06hr		38
embryo 06-08hr		38
embryo 08-10hr		38
embryo 10-12hr		35
embryo 12-14hr		22
embryo 14-16hr		25
embryo 16-18hr		17
embryo 18-20hr		11
embryo 20-22hr		15
embryo 22-24hr		13
larva L1		10
larva L2		9
larva L3 12hr old		9
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		14
white prepupae new		15
white prepupae 12hr		18
white prepupae 24hr		20
pupae 2d postWPP		18
pupae 3d postWPP		10
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		11
adult male 30day		12
adult female 01day		17
adult female 05day		21
adult female 30day		24
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		43
embryo 02-04hr		55
embryo 04-06hr		38
embryo 06-08hr		38
embryo 08-10hr		38
embryo 10-12hr		35
embryo 12-14hr		22
embryo 14-16hr		25
embryo 16-18hr		17
embryo 18-20hr		11
embryo 20-22hr		15
embryo 22-24hr		13
larva L1		10
larva L2		9
larva L3 12hr old		9
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		14
white prepupae new		15
white prepupae 12hr		18
white prepupae 24hr		20
pupae 2d postWPP		18
pupae 3d postWPP		10
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		11
adult male 30day		12
adult female 01day		17
adult female 05day		21
adult female 30day		24
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		23
embryonic 1182-4H		21
embryonic GM2		20
embryonic Kc167		26
embryonic S1		41
embryonic S3		13
leg disc CME L1		21
wing disc CME-W2		19
wing disc ML-DmD8		19
wing disc ML-DmD9		36
wing disc ML-DmD16-c3		27
wing disc ML-DmD21		34
wing disc ML-DmD32		25
haltere disc ML-DmD17-c3		34
eye-antennal disc ML-DmD11		29
antennal disc ML-DmD20-c5		31
mixed discs ML-DmD4-c1		23
CNS ML-DmBG1-c1		25
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		16
ovary fGS/OSS		33
ovary OSC		24
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(38)
Schneider line 2 Sg4		23
embryonic 1182-4H		21
embryonic GM2		20
embryonic Kc167		26
embryonic S1		(41)
embryonic S3		13
leg disc CME L1		21
wing disc CME-W2		19
wing disc ML-DmD8		19
wing disc ML-DmD9		(36)
wing disc ML-DmD16-c3		(27)
wing disc ML-DmD21		(34)
wing disc ML-DmD32		25
haltere disc ML-DmD17-c3		(34)
eye-antennal disc ML-DmD11		(29)
antennal disc ML-DmD20-c5		(31)
mixed discs ML-DmD4-c1		23
CNS ML-DmBG1-c1		25
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		16
ovary fGS/OSS		(33)
ovary OSC		24
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		23
embryonic 1182-4H		21
embryonic GM2		20
embryonic Kc167		26
embryonic S1		41
embryonic S3		13
leg disc CME L1		21
wing disc CME-W2		19
wing disc ML-DmD8		19
wing disc ML-DmD9		36
wing disc ML-DmD16-c3		27
wing disc ML-DmD21		34
wing disc ML-DmD32		25
haltere disc ML-DmD17-c3		34
eye-antennal disc ML-DmD11		29
antennal disc ML-DmD20-c5		31
mixed discs ML-DmD4-c1		23
CNS ML-DmBG1-c1		25
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		16
ovary fGS/OSS		33
ovary OSC		24
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		23
embryonic 1182-4H		21
embryonic GM2		20
embryonic Kc167		26
embryonic S1		41
embryonic S3		13
leg disc CME L1		21
wing disc CME-W2		19
wing disc ML-DmD8		19
wing disc ML-DmD9		36
wing disc ML-DmD16-c3		27
wing disc ML-DmD21		34
wing disc ML-DmD32		25
haltere disc ML-DmD17-c3		34
eye-antennal disc ML-DmD11		29
antennal disc ML-DmD20-c5		31
mixed discs ML-DmD4-c1		23
CNS ML-DmBG1-c1		25
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		16
ovary fGS/OSS		33
ovary OSC		24
ovary OSS		12
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		23
embryonic 1182-4H		21
embryonic GM2		20
embryonic Kc167		26
embryonic S1		41
embryonic S3		13
leg disc CME L1		21
wing disc CME-W2		19
wing disc ML-DmD8		19
wing disc ML-DmD9		36
wing disc ML-DmD16-c3		27
wing disc ML-DmD21		34
wing disc ML-DmD32		25
haltere disc ML-DmD17-c3		34
eye-antennal disc ML-DmD11		29
antennal disc ML-DmD20-c5		31
mixed discs ML-DmD4-c1		23
CNS ML-DmBG1-c1		25
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		16
ovary fGS/OSS		33
ovary OSC		24
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(38)
Schneider line 2 Sg4		23
embryonic 1182-4H		21
embryonic GM2		20
embryonic Kc167		26
embryonic S1		(41)
embryonic S3		13
leg disc CME L1		21
wing disc CME-W2		19
wing disc ML-DmD8		19
wing disc ML-DmD9		(36)
wing disc ML-DmD16-c3		27
wing disc ML-DmD21		(34)
wing disc ML-DmD32		25
haltere disc ML-DmD17-c3		(34)
eye-antennal disc ML-DmD11		29
antennal disc ML-DmD20-c5		31
mixed discs ML-DmD4-c1		23
CNS ML-DmBG1-c1		25
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		16
ovary fGS/OSS		(33)
ovary OSC		24
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		23
embryonic 1182-4H		21
embryonic GM2		20
embryonic Kc167		26
embryonic S1		41
embryonic S3		13
leg disc CME L1		21
wing disc CME-W2		19
wing disc ML-DmD8		19
wing disc ML-DmD9		36
wing disc ML-DmD16-c3		27
wing disc ML-DmD21		34
wing disc ML-DmD32		25
haltere disc ML-DmD17-c3		34
eye-antennal disc ML-DmD11		29
antennal disc ML-DmD20-c5		31
mixed discs ML-DmD4-c1		23
CNS ML-DmBG1-c1		25
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		16
ovary fGS/OSS		33
ovary OSC		24
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		23
embryonic 1182-4H		21
embryonic GM2		20
embryonic Kc167		26
embryonic S1		41
embryonic S3		13
leg disc CME L1		21
wing disc CME-W2		19
wing disc ML-DmD8		19
wing disc ML-DmD9		36
wing disc ML-DmD16-c3		27
wing disc ML-DmD21		34
wing disc ML-DmD32		25
haltere disc ML-DmD17-c3		34
eye-antennal disc ML-DmD11		29
antennal disc ML-DmD20-c5		31
mixed discs ML-DmD4-c1		23
CNS ML-DmBG1-c1		25
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		16
ovary fGS/OSS		33
ovary OSC		24
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		10
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		11
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		13
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		20
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		16
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		16
Paraquat 10 mM 48 hrs, 4-day adult		17
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		10
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		11
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		13
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		20
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		16
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		16
Paraquat 10 mM 48 hrs, 4-day adult		17
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		10
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		11
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		13
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		20
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		16
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		16
Paraquat 10 mM 48 hrs, 4-day adult		17
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		10
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		11
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		13
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		20
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		16
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		16
Paraquat 10 mM 48 hrs, 4-day adult		17
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		10
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		11
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		13
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		20
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		16
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		16
Paraquat 10 mM 48 hrs, 4-day adult		17
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		10
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		11
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		13
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		20
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		16
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		16
Paraquat 10 mM 48 hrs, 4-day adult		17
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		10
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		11
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		13
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		20
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		16
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		16
Paraquat 10 mM 48 hrs, 4-day adult		17
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		10
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		11
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		13
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		20
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		16
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		16
Paraquat 10 mM 48 hrs, 4-day adult		17
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

LD45447

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0039601

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG1523-RA

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG1523

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG1523^GD8951

Other Phenotypes

Allele

visible, with Scer\GAL4^pnr-MD237

CG1523^GD8951

Phenotype manifest in

Allele

chaeta | supernumerary, with Scer\GAL4^pnr-MD237

CG1523^GD8951

Classical Alleles ( 5 )

For All Classical Alleles Show

Allele of CG1523	Mutagen	Stocks	Known lesion
CG1523^e02757	piggyBac transposase	1	--
CG1523^EP313	P-element activity	1	Yes
CG1523^f01077	piggyBac transposase	1	--
CG1523^G6379	P-element activity	1	--
CG1523^e02725	piggyBac transposase	0	--

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG1523	Mutagen	Stocks	Known lesion
CG1523^GD8951	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG1523^KK101699	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes
CG1523^NIG.1523R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(3R)Exel6210

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD8951}

P{KK101699}

P{NIG.1523R}

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EP}CG1523^EP313

P{EP}CG1523^G6379

miscellaneous insertions

PBac{RB}CG1523^e02725

PBac{RB}CG1523^e02757

PBac{WH}CG1523^f01077

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

There is no information supporting a biological process, cellular component or molecular function term for this gene.

(Based on a review of available data on: 2007-10-05)

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

gene_with_edited_transcript

(Graveley et al., 2011)

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

protein-protein

Interacting group

Assay

References

CG1523 - CG10859

anti tag coimmunoprecipitation, peptide massfingerprinting

(Mintseris et al., 2009.11.23)

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG1523 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

68276

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0039601

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

43400

SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores.

•

Q9VAT2

Orthologs

OrthoDB Orthologs (37) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG605SKT

Dipteran inclusive ortholog search

EOG60GD05

Insect inclusive ortholog search

EOG6QVB76

Arthropod inclusive ortholog search

EOG6KSN12

Metazoa inclusive ortholog search

EOG6QVR5B

Orthologs in Drosophila Species (EOG605SKT)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA13587

Drosophila persimilis

Dper\GL13687

Drosophila willistoni

Dwil\GK10983

Drosophila virilis

Dvir\GJ24178

Drosophila mojavensis

Dmoj\GI10526

Drosophila grimshawi

Dgri\GH18094

Orthologs in non-Drosophila Dipterans (EOG60GD05)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL013887

Anopheles gambiae

Malaria mosquito

Agam\AGAP010182

Anopheles gambiae

Malaria mosquito

Agam\AGAP000200

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ005560

Orthologs in non-Dipteran Insects (EOG6QVB76)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\LOC412997

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG001658

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH20034

Atta cephalotes

Leafcutter ant

Acep\ACEP27692

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO17567

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL21364

Linepithema humile

Argentine ant

Lhum\LH21116

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB25897

Solenopsis invicta

Red fire ant

Sinv\SINV12906

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI008681

Bombyx mori

Silkmoth

Bmor\BGIBMGA004849

Pediculus humanus

Human body louse

Phum\PHUM204570

Tribolium castaneum

Red flour beetle

Tcas\TC010660

Orthologs in non-Insect Arthropods (EOG6KSN12)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\JGI_V11_324775

Orthologs in non-Arthropod Metazoa (EOG6QVR5B)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_011317gn

Danio rerio

Zebrafish

Drer\wdr32

Xenopus tropicalis

Western clawed frog

Xtro\dcaf10

Gallus gallus

Domestic chicken

Ggal\DCAF10

Mus musculus

House mouse

Mmus\Dcaf10

Rattus norvegicus

Norway rat

Rnor\Dcaf10

Homo sapiens

Human

Hsap\DCAF10

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\DCAF10

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA13587

Drosophila persimilis

Dper\GL13687

Drosophila willistoni

Dwil\GK10983

Drosophila virilis

Dvir\GJ24178

Drosophila mojavensis

Dmoj\GI10526

Drosophila grimshawi

Dgri\GH18094

Stocks & Reagents

Stocks Listed in FlyBase ( 5 )

Bloomington

17091

w¹¹¹⁸; P{EP}CG1523^EP313

31797

w¹¹¹⁸; P{EP}CG1523^G6379/TM6C, Sb¹

Harvard

PBac{RB}CG1523^e02757

PBac{WH}CG1523^f01077

VDRC

v25199

w¹¹¹⁸; P{GD8951}v25199/TM3

Genomic Clones ( 1 )

BACR48K07

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 52 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones