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Gene Dmel\β4GalNAcTB

General Information
Symbol	Dmel\β4GalNAcTB	Species	D. melanogaster
Name	β4GalNAcTB	Annotation symbol	CG14517
Feature type	protein_coding_gene	FlyBase ID	FBgn0039625
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	98F5-98F5	Sequence location	3R:24,858,382..24,859,730 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene β4GalNAcTB is referred to in FlyBase by the symbol Dmel\β4GalNAcTB (CG14517, FBgn0039625). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity; acetylgalactosaminyltransferase activity. There is experimental evidence that it is involved in the biological process: N-acetylglucosamine metabolic process; glycolipid biosynthetic process. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Galactosyltransferase, metazoa. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1637032_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of beta4GalNAcTB. Gene sequence location is 3R:24858382..24859730.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Kraft et al., 2011, Cell. Molec. Life Sci. 68(24): 4091--4100 Sequence features HFA14869 BKN25023
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 98F5-98F5   Limits computationally determined from genome sequence between P{PZ}l(3)0648706487 and P{EP}EP3390EP3390
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\β4GalNAcTB for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) β4GalNAcTB-RA FBtr0085419  NM_143400   1349   323
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein β4GalNAcTB-PA   FBpp0084788   37.8   323   7.09     NP_651657   AAF56843
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Galactosyltransferase, metazoa (IPR003859)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF56843   BI236006   BI236014   BI369583   BT003627 AAO39631   BT011457   CO263866   CO271521   CO277454   CO288295   CO342002   CO345118   EC196202   EC197611   EC198418   EC255999   EC258637
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q86NU9 Q9VAQ8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039625    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039625 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039625 expression level Developmental Stage   Expression Level embryo 00-02hr    3862 embryo 02-04hr    2417 embryo 04-06hr    2943 embryo 06-08hr    1497 embryo 08-10hr    1190 embryo 10-12hr    908 embryo 12-14hr    545 embryo 14-16hr    570 embryo 16-18hr    492 embryo 18-20hr    376 embryo 20-22hr    395 embryo 22-24hr    451 larva L1    954 larva L2    968 larva L3 12hr old    962 larva L3 puffstage 1-2    1153 larva L3 puffstage 3-6    1044 larva L3 puffstage 7-9    1134 white prepupae new    978 white prepupae 12hr    960 white prepupae 24hr    1051 pupae 2d postWPP    758 pupae 3d postWPP    713 pupae 4d postWPP    980 adult male 01day    697 adult male 05day    871 adult male 30day    884 adult female 01day    1900 adult female 05day    2367 adult female 30day    2686 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3862) embryo 02-04hr  (2417) embryo 04-06hr  (2943) embryo 06-08hr  (1497) embryo 08-10hr  (1190) embryo 10-12hr  (908) embryo 12-14hr  (545) embryo 14-16hr  (570) embryo 16-18hr  (492) embryo 18-20hr  (376) embryo 20-22hr  (395) embryo 22-24hr  (451) larva L1  (954) larva L2  (968) larva L3 12hr old  (962) larva L3 puffstage 1-2  (1153) larva L3 puffstage 3-6  (1044) larva L3 puffstage 7-9  (1134) white prepupae new  (978) white prepupae 12hr  (960) white prepupae 24hr  (1051) pupae 2d postWPP  (758) pupae 3d postWPP  (713) pupae 4d postWPP  (980) adult male 01day  (697) adult male 05day  (871) adult male 30day  (884) adult female 01day  (1900) adult female 05day  (2367) adult female 30day  (2686) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3862) embryo 02-04hr  (2417) embryo 04-06hr  (2943) embryo 06-08hr  1497 embryo 08-10hr    1190 embryo 10-12hr    908 embryo 12-14hr    545 embryo 14-16hr    570 embryo 16-18hr    492 embryo 18-20hr    376 embryo 20-22hr    395 embryo 22-24hr    451 larva L1    954 larva L2    968 larva L3 12hr old    962 larva L3 puffstage 1-2    1153 larva L3 puffstage 3-6    1044 larva L3 puffstage 7-9    1134 white prepupae new    978 white prepupae 12hr    960 white prepupae 24hr    1051 pupae 2d postWPP    758 pupae 3d postWPP    713 pupae 4d postWPP    980 adult male 01day    697 adult male 05day    871 adult male 30day    884 adult female 01day  (1900) adult female 05day  (2367) adult female 30day  (2686) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3862 embryo 02-04hr    2417 embryo 04-06hr    2943 embryo 06-08hr    1497 embryo 08-10hr    1190 embryo 10-12hr    908 embryo 12-14hr    545 embryo 14-16hr    570 embryo 16-18hr    492 embryo 18-20hr    376 embryo 20-22hr    395 embryo 22-24hr    451 larva L1    954 larva L2    968 larva L3 12hr old    962 larva L3 puffstage 1-2    1153 larva L3 puffstage 3-6    1044 larva L3 puffstage 7-9    1134 white prepupae new    978 white prepupae 12hr    960 white prepupae 24hr    1051 pupae 2d postWPP    758 pupae 3d postWPP    713 pupae 4d postWPP    980 adult male 01day    697 adult male 05day    871 adult male 30day    884 adult female 01day    1900 adult female 05day    2367 adult female 30day    2686 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3862 embryo 02-04hr    2417 embryo 04-06hr    2943 embryo 06-08hr    1497 embryo 08-10hr    1190 embryo 10-12hr    908 embryo 12-14hr    545 embryo 14-16hr    570 embryo 16-18hr    492 embryo 18-20hr    376 embryo 20-22hr    395 embryo 22-24hr    451 larva L1    954 larva L2    968 larva L3 12hr old    962 larva L3 puffstage 1-2    1153 larva L3 puffstage 3-6    1044 larva L3 puffstage 7-9    1134 white prepupae new    978 white prepupae 12hr    960 white prepupae 24hr    1051 pupae 2d postWPP    758 pupae 3d postWPP    713 pupae 4d postWPP    980 adult male 01day    697 adult male 05day    871 adult male 30day    884 adult female 01day    1900 adult female 05day    2367 adult female 30day    2686 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039625 expression level Developmental Stage   Expression Level embryo 00-02hr    3862 embryo 02-04hr    2417 embryo 04-06hr    2943 embryo 06-08hr    1497 embryo 08-10hr    1190 embryo 10-12hr    908 embryo 12-14hr    545 embryo 14-16hr    570 embryo 16-18hr    492 embryo 18-20hr    376 embryo 20-22hr    395 embryo 22-24hr    451 larva L1    954 larva L2    968 larva L3 12hr old    962 larva L3 puffstage 1-2    1153 larva L3 puffstage 3-6    1044 larva L3 puffstage 7-9    1134 white prepupae new    978 white prepupae 12hr    960 white prepupae 24hr    1051 pupae 2d postWPP    758 pupae 3d postWPP    713 pupae 4d postWPP    980 adult male 01day    697 adult male 05day    871 adult male 30day    884 adult female 01day    1900 adult female 05day    2367 adult female 30day    2686 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3862) embryo 02-04hr  (2417) embryo 04-06hr  (2943) embryo 06-08hr  (1497) embryo 08-10hr  (1190) embryo 10-12hr  (908) embryo 12-14hr  (545) embryo 14-16hr  (570) embryo 16-18hr  (492) embryo 18-20hr  (376) embryo 20-22hr  (395) embryo 22-24hr  (451) larva L1  (954) larva L2  (968) larva L3 12hr old  (962) larva L3 puffstage 1-2  (1153) larva L3 puffstage 3-6  (1044) larva L3 puffstage 7-9  (1134) white prepupae new  (978) white prepupae 12hr  (960) white prepupae 24hr  (1051) pupae 2d postWPP  (758) pupae 3d postWPP  (713) pupae 4d postWPP  (980) adult male 01day  (697) adult male 05day  (871) adult male 30day  (884) adult female 01day  (1900) adult female 05day  (2367) adult female 30day  (2686) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3862) embryo 02-04hr  2417 embryo 04-06hr  (2943) embryo 06-08hr  1497 embryo 08-10hr    1190 embryo 10-12hr    908 embryo 12-14hr    545 embryo 14-16hr    570 embryo 16-18hr    492 embryo 18-20hr    376 embryo 20-22hr    395 embryo 22-24hr    451 larva L1    954 larva L2    968 larva L3 12hr old    962 larva L3 puffstage 1-2    1153 larva L3 puffstage 3-6    1044 larva L3 puffstage 7-9    1134 white prepupae new    978 white prepupae 12hr    960 white prepupae 24hr    1051 pupae 2d postWPP    758 pupae 3d postWPP    713 pupae 4d postWPP    980 adult male 01day    697 adult male 05day    871 adult male 30day    884 adult female 01day  1900 adult female 05day  2367 adult female 30day  (2686) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3862 embryo 02-04hr    2417 embryo 04-06hr    2943 embryo 06-08hr    1497 embryo 08-10hr    1190 embryo 10-12hr    908 embryo 12-14hr    545 embryo 14-16hr    570 embryo 16-18hr    492 embryo 18-20hr    376 embryo 20-22hr    395 embryo 22-24hr    451 larva L1    954 larva L2    968 larva L3 12hr old    962 larva L3 puffstage 1-2    1153 larva L3 puffstage 3-6    1044 larva L3 puffstage 7-9    1134 white prepupae new    978 white prepupae 12hr    960 white prepupae 24hr    1051 pupae 2d postWPP    758 pupae 3d postWPP    713 pupae 4d postWPP    980 adult male 01day    697 adult male 05day    871 adult male 30day    884 adult female 01day    1900 adult female 05day    2367 adult female 30day    2686 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3862 embryo 02-04hr    2417 embryo 04-06hr    2943 embryo 06-08hr    1497 embryo 08-10hr    1190 embryo 10-12hr    908 embryo 12-14hr    545 embryo 14-16hr    570 embryo 16-18hr    492 embryo 18-20hr    376 embryo 20-22hr    395 embryo 22-24hr    451 larva L1    954 larva L2    968 larva L3 12hr old    962 larva L3 puffstage 1-2    1153 larva L3 puffstage 3-6    1044 larva L3 puffstage 7-9    1134 white prepupae new    978 white prepupae 12hr    960 white prepupae 24hr    1051 pupae 2d postWPP    758 pupae 3d postWPP    713 pupae 4d postWPP    980 adult male 01day    697 adult male 05day    871 adult male 30day    884 adult female 01day    1900 adult female 05day    2367 adult female 30day    2686 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0039625    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0039625 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0039625 expression level Tissue   Expression Level Larval Central Nervous System    127.3 Larval Midgut    212.7 Larval Hindgut    203.4 Larval Malpighian Tubules    283.6 Larval Fat Body    46.2 Larval Salivary Gland    191 Larval Trachea    179 Larval Carcass    137.3 Adult Head    45.9 Adult Eye    45.5 Adult Brain    93 Adult Thoracic-Abdominal Ganglion    112.5 Adult Crop    96.4 Adult Midgut    171.6 Adult Hindgut    102.2 Adult Malpighian Tubules    66.8 Adult Fat Body    31.8 Adult Salivary Gland    153.6 Adult Heart    74.075 Adult VirginFemale Spermatheca    26.7 Adult InseminatedFemale Spermatheca    29.2 Adult Ovary    129.4 Adult Testis    19.7 Adult Male Accessory Gland    148.6 Adult Carcass    45.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    127.3 Larval Midgut    212.7 Larval Hindgut    203.4 Larval Malpighian Tubules    283.6 Larval Fat Body    46.2 Larval Salivary Gland    191 Larval Trachea    179 Larval Carcass    137.3 Adult Head    45.9 Adult Eye    45.5 Adult Brain    93 Adult Thoracic-Abdominal Ganglion    112.5 Adult Crop    96.4 Adult Midgut    171.6 Adult Hindgut    102.2 Adult Malpighian Tubules    66.8 Adult Fat Body    31.8 Adult Salivary Gland    153.6 Adult Heart    74.075 Adult VirginFemale Spermatheca    26.7 Adult InseminatedFemale Spermatheca    29.2 Adult Ovary    129.4 Adult Testis    19.7 Adult Male Accessory Gland    148.6 Adult Carcass    45.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    127.3 Larval Midgut    212.7 Larval Hindgut    203.4 Larval Malpighian Tubules    283.6 Larval Fat Body    46.2 Larval Salivary Gland    191 Larval Trachea    179 Larval Carcass    137.3 Adult Head    45.9 Adult Eye    45.5 Adult Brain    93 Adult Thoracic-Abdominal Ganglion    112.5 Adult Crop    96.4 Adult Midgut    171.6 Adult Hindgut    102.2 Adult Malpighian Tubules    66.8 Adult Fat Body    31.8 Adult Salivary Gland    153.6 Adult Heart    74.075 Adult VirginFemale Spermatheca    26.7 Adult InseminatedFemale Spermatheca    29.2 Adult Ovary    129.4 Adult Testis    19.7 Adult Male Accessory Gland    148.6 Adult Carcass    45.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    127.3 Larval Midgut    212.7 Larval Hindgut    203.4 Larval Malpighian Tubules    283.6 Larval Fat Body    46.2 Larval Salivary Gland    191 Larval Trachea    179 Larval Carcass    137.3 Adult Head    45.9 Adult Eye    45.5 Adult Brain    93 Adult Thoracic-Abdominal Ganglion    112.5 Adult Crop    96.4 Adult Midgut    171.6 Adult Hindgut    102.2 Adult Malpighian Tubules    66.8 Adult Fat Body    31.8 Adult Salivary Gland    153.6 Adult Heart    74.075 Adult VirginFemale Spermatheca    26.7 Adult InseminatedFemale Spermatheca    29.2 Adult Ovary    129.4 Adult Testis    19.7 Adult Male Accessory Gland    148.6 Adult Carcass    45.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0039625 expression level Tissue   Expression Level Larval Central Nervous System    127.3 Larval Midgut    212.7 Larval Hindgut    203.4 Larval Malpighian Tubules    283.6 Larval Fat Body    46.2 Larval Salivary Gland    191 Larval Trachea    179 Larval Carcass    137.3 Adult Head    45.9 Adult Eye    45.5 Adult Brain    93 Adult Thoracic-Abdominal Ganglion    112.5 Adult Crop    96.4 Adult Midgut    171.6 Adult Hindgut    102.2 Adult Malpighian Tubules    66.8 Adult Fat Body    31.8 Adult Salivary Gland    153.6 Adult Heart    74.075 Adult VirginFemale Spermatheca    26.7 Adult InseminatedFemale Spermatheca    29.2 Adult Ovary    129.4 Adult Testis    19.7 Adult Male Accessory Gland    148.6 Adult Carcass    45.9 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    127.3 Larval Midgut    212.7 Larval Hindgut    203.4 Larval Malpighian Tubules    283.6 Larval Fat Body    46.2 Larval Salivary Gland    191 Larval Trachea    179 Larval Carcass    137.3 Adult Head    45.9 Adult Eye    45.5 Adult Brain    93 Adult Thoracic-Abdominal Ganglion    112.5 Adult Crop    96.4 Adult Midgut    171.6 Adult Hindgut    102.2 Adult Malpighian Tubules    66.8 Adult Fat Body    31.8 Adult Salivary Gland    153.6 Adult Heart    74.075 Adult VirginFemale Spermatheca    26.7 Adult InseminatedFemale Spermatheca    29.2 Adult Ovary    129.4 Adult Testis    19.7 Adult Male Accessory Gland    148.6 Adult Carcass    45.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    127.3 Larval Midgut    212.7 Larval Hindgut    203.4 Larval Malpighian Tubules    283.6 Larval Fat Body    46.2 Larval Salivary Gland    191 Larval Trachea    179 Larval Carcass    137.3 Adult Head    45.9 Adult Eye    45.5 Adult Brain    93 Adult Thoracic-Abdominal Ganglion    112.5 Adult Crop    96.4 Adult Midgut    171.6 Adult Hindgut    102.2 Adult Malpighian Tubules    66.8 Adult Fat Body    31.8 Adult Salivary Gland    153.6 Adult Heart    74.075 Adult VirginFemale Spermatheca    26.7 Adult InseminatedFemale Spermatheca    29.2 Adult Ovary    129.4 Adult Testis    19.7 Adult Male Accessory Gland    148.6 Adult Carcass    45.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    127.3 Larval Midgut    212.7 Larval Hindgut    203.4 Larval Malpighian Tubules    283.6 Larval Fat Body    46.2 Larval Salivary Gland    191 Larval Trachea    179 Larval Carcass    137.3 Adult Head    45.9 Adult Eye    45.5 Adult Brain    93 Adult Thoracic-Abdominal Ganglion    112.5 Adult Crop    96.4 Adult Midgut    171.6 Adult Hindgut    102.2 Adult Malpighian Tubules    66.8 Adult Fat Body    31.8 Adult Salivary Gland    153.6 Adult Heart    74.075 Adult VirginFemale Spermatheca    26.7 Adult InseminatedFemale Spermatheca    29.2 Adult Ovary    129.4 Adult Testis    19.7 Adult Male Accessory Gland    148.6 Adult Carcass    45.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    45.9   NA  Eye    45.5   NA  Brain    93   127.3  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    112.5   NA  Crop    96.4   212.7  Midgut    171.6   203.4  Hindgut    102.2   283.6  Malpighian Tubules    66.8   46.2  Fat Body    31.8   191  Salivary Gland    153.6   NA  Heart    74.075   179  Trachea    NA   NA  VirginFemale Spermatheca    26.7   NA  InseminatedFemale Spermatheca    29.2   NA  Ovary    129.4   NA  Testis    19.7   NA  Male Accessory Gland    148.6   137.3  Carcass    45.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039625 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14517-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable β4GalNAcTBGT viable, with Scer\GAL4pnr-MD237 β4GalNAcTBGD3530 Sterility Allele fertile β4GalNAcTBGT Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of β4GalNAcTB Class Mutagen Stocks Known lesion β4GalNAcTBGT recombination FLPase 1 Yes
Alleles Carried on Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Allele of β4GalNAcTB Class Mutagen Stocks Known lesion β4GalNAcTBGD3530 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes β4GalNAcTBScer\UAS.cIa in vitro construct - regulatory fusion 2 Yes β4GalNAcTBKK104063 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes β4GalNAcTBBIP.MtnA.T:SV5\V5,T:Zzzz\His6 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes β4GalNAcTBBIP.MtnA in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes β4GalNAcTBEndsOut.H in vitro construct 0 Yes β4GalNAcTBMtnA.PH in vitro construct - regulatory fusion 0 Yes β4GalNAcTBMtnA.T:SV5\V5,T:Zzzz\His6 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6211 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data characterization construct P{EndsOut-β4GalNAcTB.H} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function
CV term Evidence References
acetylgalactosaminyltransferase activity inferred from direct assay (Haines and Irvine, 2005) N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity inferred from direct assay (Johswich et al., 2009)
Biological Process
CV term Evidence References
glycolipid biosynthetic process inferred from direct assay (Johswich et al., 2009) N-acetylglucosamine metabolic process inferred from direct assay (Haines and Irvine, 2005)
Cellular Component
CV term Evidence References
Golgi apparatus inferred from direct assay (Johswich et al., 2009)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions β4GalNAcTB allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039625 DroID - A comprehensive database of gene and protein interactions. • FBgn0039625
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18727 Dere\GG12042 Dgri\GH23682 Dmoj\GI24526 Dper\GL23283 Dpse\GA13048 Dsec\GM12269 Dsim\GD18000 Dvir\GJ22594 Dwil\GK22603 Dyak\GE10481
Curated drosophilid orthologs	Dpse\GA13048
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL006426-PA Aedes aegypti (mosquito) AGAP008285-PA Anopheles gambiae (mosquito) XP_624523.2 Apis mellifera (honey bee) 61044 Daphnia pulex (daphnia) XP_001603169.1 Nasonia vitripennis (wasp) PHUM004468-PA Pediculus humanus (human body louse) XP_971942.2 Tribolium castaneum (red flour beetle) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15193 NV11644 NV11098 LH21953 LH15769 ISCW004931 ISCW004365 FBgn0231232 FBgn0228342 FBgn0224580 FBgn0222778 FBgn0209700 FBgn0209505 FBgn0189546 FBgn0182795 FBgn0176405 FBgn0167206 JGI_V11_322293 JGI_V11_61044 JGI_V11_48989 JGI_V11_301777 JGI_V11_111185 JGI_V11_60154 JGI_V11_14909 JGI_V11_66403 JGI_V11_71282 FBgn0081133 FBgn0073086 FBgn0160873 FBgn0147736 FBgn0147248 FBgn0143277 FBgn0027538 FBgn0131139 FBgn0129254 FBgn0112629 FBgn0104334 FBgn0095744 FBgn0090519 CPIJ014764 BGIBMGA007485 BGIBMGA005525 ACYPI006328 ACYPI002137 GB19534 GB16390 AGAP008285 AGAP004781 AAEL012002 AAEL006426 AAEL005302 PB20052 PHUM125800 PHUM256250 GLEAN_06987 GLEAN_06388
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	9380 w*; β4GalNAcTBGT 9896 P{UAS-β4GalNAcTB.I}1.2, w* 9897 w*; P{UAS-β4GalNAcTB.I}5.1/CyO, P{ActGFP}JMR1
VDRC	v105861 P{KK104063}VIE-260B v42693 w1118; P{GD3530}v42693 v42694 w1118; P{GD3530}v42694
Genomic Clones ( 1 )
	BACR11O03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 16 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT31631 RE31995
Other clones	DPiM_RE31995
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE31983 RE55808
Other clones	29056 214215.4 214253.8 CK01.86B.H2 CK01.169B.B10 EK068161 EK103739 EK124708 EK136720 EP13618 EP21343
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039625 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43425
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143400 RefSeq (Proteins) • NP_651657 DDBJ / EMBL / GenBank • AAF56843 AAO39631 BI236014 BT003627 Entrez Gene - A searchable database of RefSeq genes. • 43425 UniProtKB/TrEMBL • Q9VAQ8 Q86NU9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Galactosyltransferase, metazoa (IPR003859)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039625 DroID - A comprehensive database of gene and protein interactions. • FBgn0039625 DRSC - Results from RNAi screens. • FBgn0039625 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039625 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14517-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039625 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43425 InParanoid A subset of ortholog calls from InParanoid. • AAEL006426-PA Aedes aegypti (mosquito) AGAP008285-PA Anopheles gambiae (mosquito) XP_624523.2 Apis mellifera (honey bee) 61044 Daphnia pulex (daphnia) XP_001603169.1 Nasonia vitripennis (wasp) PHUM004468-PA Pediculus humanus (human body louse) XP_971942.2 Tribolium castaneum (red flour beetle) modMine - Data generated by the modENCODE project. • FBgn0039625 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15193 NV11644 NV11098 LH21953 LH15769 ISCW004931 ISCW004365 FBgn0231232 FBgn0228342 FBgn0224580 FBgn0222778 FBgn0209700 FBgn0209505 FBgn0189546 FBgn0182795 FBgn0176405 FBgn0167206 JGI_V11_322293 JGI_V11_61044 JGI_V11_48989 JGI_V11_301777 JGI_V11_111185 JGI_V11_60154 JGI_V11_14909 JGI_V11_66403 JGI_V11_71282 FBgn0081133 FBgn0073086 FBgn0160873 FBgn0147736 FBgn0147248 FBgn0143277 FBgn0027538 FBgn0131139 FBgn0129254 FBgn0112629 FBgn0104334 FBgn0095744 FBgn0090519 CPIJ014764 BGIBMGA007485 BGIBMGA005525 ACYPI006328 ACYPI002137 GB19534 GB16390 AGAP008285 AGAP004781 AAEL012002 AAEL006426 AAEL005302 PB20052 PHUM125800 PHUM256250 GLEAN_06987 GLEAN_06388
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	beta4GalNAcTB (Cook, 2007.1.23) CG14517 (Haines and Irvine, 2005, Huang et al., 2008, Chen et al., 2007, Keleman et al., 2009.8.5, Johswich et al., 2009) dβ4GalTB (Takemae et al., 2003) β4GalNAcTB (Xu et al., 2007, Chen et al., 2007, Johswich et al., 2009) β4GalTB
Name Synonym	β4GalNAcTB
Secondary FlyBase IDs
References ( 17 )
Research paper	Kraft et al., 2011, Cell. Molec. Life Sci. 68(24): 4091--4100 "Add-on" domains of Drosophila β1,4-N-acetylgalactosaminyltransferase B in the stem region and its pilot protein. [FBrf0216778] Johswich et al., 2009, J. Cell Biol. 184(1): 173--183 Golgi targeting of Drosophila melanogaster beta4GalNAcTB requires a DHHC protein family-related protein as a pilot. [FBrf0206521] Chen et al., 2007, Dev. Biol. 306(2): 736--749 Glycosphingolipids with extended sugar chain have specialized functions in development and behavior of Drosophila. [FBrf0202039] Xu et al., 2007, J. Biol. Chem. 282(48): 35153--35162 In vitro reconstitution of the modulation of Drosophila notch-ligand binding by fringe. [FBrf0202801] Haines and Irvine, 2005, Glycobiology 15(4): 335--346 Functional analysis of Drosophila 1,4-N-acetlygalactosaminyltransferases. [FBrf0182892] Takemae et al., 2003, J. Biol. Chem. 278(18): 15571--15578 Proteoglycan UDP-galactose:β-xylose β1,4-galactosyltransferase I is essential for viability in Drosophila melanogaster. [FBrf0159024]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Huang et al., 2008, Genetics 180(1): Supplemental Figures and Material. [FBrf0206395]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Cook, 2007.1.23, P{UAS-beta4GalNAcTA.I} & P{UAS-beta4GalNAcTB.I} constructs and insertions. P{UAS-beta4GalNAcTA.I} & P{UAS-beta4GalNAcTB.I} constructs and insertions. [FBrf0195902] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Curated genome annotation	Ashburner, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126651]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]