General Information Symbol Dmel\ Obp99cSpecies D. melanogaster Name Odorant-binding protein 99c Annotation symbol CG7584 Feature type protein_coding_gene FlyBase ID FBgn0039682 Gene Model Status Current Stock availability 1 publicly
available Also Known As Obp99b Genomic Location Chromosome (arm) 3R Recombination map Cytogenetic map 99B7-99B7 Sequence location 3R:25,511,458..25,515,033 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
Odorant-binding protein 99c is referred to in FlyBase by the symbol
Dmel\Obp99c (CG7584, FBgn0039682). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : odorant binding. Based on sequence similarity, it is predicted to be involved in the
biological process : sensory perception of chemical stimulus.
3 alleles are reported . The
phenotype of these alleles is annotated with: trichogen cell. It has
2 annotated transcripts and
2 annotated polypeptides .
Protein features are: Pheromone/general odorant binding protein; Pheromone/general odorant binding protein, PBP/GOBP, domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very low expression. Peak expression observed during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult hindgut, adult heart, larval/adult fat body, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, adult crop. Comments on Affy2 ProbeSet: ProbeSet 1625122_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Obp99c. Gene sequence location is
3R:25511458..25515033 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.46
Gene model reviewed during 5.49
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript Expression
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
0.5
Larval Midgut
3.3
Larval Hindgut
61
Larval Malpighian Tubules
20.4
Larval Fat Body
7126.2
Larval Salivary Gland
85.5
Larval Trachea
62.325
Larval Carcass
21.575
Adult Head
3251.5
Adult Eye
2312
Adult Brain
201
Adult Thoracic-Abdominal Ganglion
212.9
Adult Crop
155.8
Adult Midgut
2.3
Adult Hindgut
520.7
Adult Malpighian Tubules
43
Adult Fat Body
5093.6
Adult Salivary Gland
18
Adult Heart
4343.15
Adult VirginFemale Spermatheca
2977.8
Adult InseminatedFemale Spermatheca
2482.8
Adult Ovary
0.8
Adult Testis
6.4
Adult Male Accessory Gland
3.5
Adult Carcass
4836.3
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
0.5
Larval Midgut
3.3
Larval Hindgut
61
Larval Malpighian Tubules
20.4
Larval Fat Body
(7126.2)
Larval Salivary Gland
85.5
Larval Trachea
62.325
Larval Carcass
21.575
Adult Head
(3251.5)
Adult Eye
(2312)
Adult Brain
201
Adult Thoracic-Abdominal Ganglion
212.9
Adult Crop
155.8
Adult Midgut
2.3
Adult Hindgut
520.7
Adult Malpighian Tubules
43
Adult Fat Body
(5093.6)
Adult Salivary Gland
18
Adult Heart
(4343.15)
Adult VirginFemale Spermatheca
(2977.8)
Adult InseminatedFemale Spermatheca
(2482.8)
Adult Ovary
0.8
Adult Testis
6.4
Adult Male Accessory Gland
3.5
Adult Carcass
(4836.3)
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
0.5
Larval Midgut
3.3
Larval Hindgut
61
Larval Malpighian Tubules
20.4
Larval Fat Body
(7126.2)
Larval Salivary Gland
85.5
Larval Trachea
62.325
Larval Carcass
21.575
Adult Head
(3251.5)
Adult Eye
(2312)
Adult Brain
201
Adult Thoracic-Abdominal Ganglion
212.9
Adult Crop
155.8
Adult Midgut
2.3
Adult Hindgut
520.7
Adult Malpighian Tubules
43
Adult Fat Body
(5093.6)
Adult Salivary Gland
18
Adult Heart
(4343.15)
Adult VirginFemale Spermatheca
(2977.8)
Adult InseminatedFemale Spermatheca
(2482.8)
Adult Ovary
0.8
Adult Testis
6.4
Adult Male Accessory Gland
3.5
Adult Carcass
(4836.3)
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
0.5
Larval Midgut
3.3
Larval Hindgut
61
Larval Malpighian Tubules
20.4
Larval Fat Body
7126.2
Larval Salivary Gland
85.5
Larval Trachea
62.325
Larval Carcass
21.575
Adult Head
3251.5
Adult Eye
2312
Adult Brain
201
Adult Thoracic-Abdominal Ganglion
212.9
Adult Crop
155.8
Adult Midgut
2.3
Adult Hindgut
520.7
Adult Malpighian Tubules
43
Adult Fat Body
5093.6
Adult Salivary Gland
18
Adult Heart
4343.15
Adult VirginFemale Spermatheca
2977.8
Adult InseminatedFemale Spermatheca
2482.8
Adult Ovary
0.8
Adult Testis
6.4
Adult Male Accessory Gland
3.5
Adult Carcass
4836.3
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
0.5
Larval Midgut
3.3
Larval Hindgut
61
Larval Malpighian Tubules
20.4
Larval Fat Body
7126.2
Larval Salivary Gland
85.5
Larval Trachea
62.325
Larval Carcass
21.575
Adult Head
3251.5
Adult Eye
2312
Adult Brain
201
Adult Thoracic-Abdominal Ganglion
212.9
Adult Crop
155.8
Adult Midgut
2.3
Adult Hindgut
520.7
Adult Malpighian Tubules
43
Adult Fat Body
5093.6
Adult Salivary Gland
18
Adult Heart
4343.15
Adult VirginFemale Spermatheca
2977.8
Adult InseminatedFemale Spermatheca
2482.8
Adult Ovary
0.8
Adult Testis
6.4
Adult Male Accessory Gland
3.5
Adult Carcass
4836.3
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
0.5
Larval Midgut
3.3
Larval Hindgut
61
Larval Malpighian Tubules
20.4
Larval Fat Body
(7126.2)
Larval Salivary Gland
85.5
Larval Trachea
62.325
Larval Carcass
21.575
Adult Head
(3251.5)
Adult Eye
(2312)
Adult Brain
201
Adult Thoracic-Abdominal Ganglion
212.9
Adult Crop
155.8
Adult Midgut
2.3
Adult Hindgut
520.7
Adult Malpighian Tubules
43
Adult Fat Body
(5093.6)
Adult Salivary Gland
18
Adult Heart
(4343.15)
Adult VirginFemale Spermatheca
(2977.8)
Adult InseminatedFemale Spermatheca
(2482.8)
Adult Ovary
0.8
Adult Testis
6.4
Adult Male Accessory Gland
3.5
Adult Carcass
(4836.3)
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
0.5
Larval Midgut
3.3
Larval Hindgut
61
Larval Malpighian Tubules
20.4
Larval Fat Body
(7126.2)
Larval Salivary Gland
85.5
Larval Trachea
62.325
Larval Carcass
21.575
Adult Head
(3251.5)
Adult Eye
(2312)
Adult Brain
201
Adult Thoracic-Abdominal Ganglion
212.9
Adult Crop
155.8
Adult Midgut
2.3
Adult Hindgut
520.7
Adult Malpighian Tubules
43
Adult Fat Body
(5093.6)
Adult Salivary Gland
18
Adult Heart
(4343.15)
Adult VirginFemale Spermatheca
(2977.8)
Adult InseminatedFemale Spermatheca
(2482.8)
Adult Ovary
0.8
Adult Testis
6.4
Adult Male Accessory Gland
3.5
Adult Carcass
(4836.3)
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
0.5
Larval Midgut
3.3
Larval Hindgut
61
Larval Malpighian Tubules
20.4
Larval Fat Body
7126.2
Larval Salivary Gland
85.5
Larval Trachea
62.325
Larval Carcass
21.575
Adult Head
3251.5
Adult Eye
2312
Adult Brain
201
Adult Thoracic-Abdominal Ganglion
212.9
Adult Crop
155.8
Adult Midgut
2.3
Adult Hindgut
520.7
Adult Malpighian Tubules
43
Adult Fat Body
5093.6
Adult Salivary Gland
18
Adult Heart
4343.15
Adult VirginFemale Spermatheca
2977.8
Adult InseminatedFemale Spermatheca
2482.8
Adult Ovary
0.8
Adult Testis
6.4
Adult Male Accessory Gland
3.5
Adult Carcass
4836.3
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
3251.5
NA
Eye
2312
NA
Brain
201
0.5
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
212.9
NA
Crop
155.8
3.3
Midgut
2.3
61
Hindgut
520.7
no informative data
Malpighian Tubules
no informative data
7126.2
Fat Body
5093.6
85.5
Salivary Gland
no informative data
NA
Heart
4343.15
no informative data
Trachea
NA
NA
VirginFemale Spermatheca
2977.8
NA
InseminatedFemale Spermatheca
2482.8
NA
Ovary
0.8
NA
Testis
6.4
NA
Male Accessory Gland
3.5
no informative data
Carcass
4836.3
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
2
central nervous system, larvae L3
4
central nervous system, pupae P8
20
head, virgin 1-day female
486
head, virgin 4-day female
291
head, virgin 20-day female
728
head, mated 1-day female
330
head, mated 4-day female
399
head, mated 20-day female
570
head, mated 1-day male
630
head, mated 4-day male
605
head, mated 20-day male
891
salivary gland, larvae L3 wandering
19
salivary gland, white prepupae
56
digestive system, larvae L3 wandering
24
digestive system, 1-day adult
84
digestive system, 4-day adult
27
digestive system, 20-day adult
21
fat body, larvae L3 wandering
822
fat body, white prepupae
611
fat body, pupae P8
1766
carcass, larvae L3 wandering
23
carcass, 1-day adult
506
carcass, 4-day adult
304
carcass, 20-day adult
400
ovary, virgin 4-day female
1
ovary, mated 4-day female
0
testis, mated 4-day male
35
accessory gland, mated 4-day male
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
2
central nervous system, larvae L3
4
central nervous system, pupae P8
20
head, virgin 1-day female
(486)
head, virgin 4-day female
(291)
head, virgin 20-day female
(728)
head, mated 1-day female
(330)
head, mated 4-day female
(399)
head, mated 20-day female
(570)
head, mated 1-day male
(630)
head, mated 4-day male
(605)
head, mated 20-day male
(891)
salivary gland, larvae L3 wandering
19
salivary gland, white prepupae
(56)
digestive system, larvae L3 wandering
24
digestive system, 1-day adult
(84)
digestive system, 4-day adult
(27)
digestive system, 20-day adult
21
fat body, larvae L3 wandering
(822)
fat body, white prepupae
(611)
fat body, pupae P8
(1766)
carcass, larvae L3 wandering
23
carcass, 1-day adult
(506)
carcass, 4-day adult
(304)
carcass, 20-day adult
(400)
ovary, virgin 4-day female
1
ovary, mated 4-day female
0
testis, mated 4-day male
(35)
accessory gland, mated 4-day male
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
2
central nervous system, larvae L3
4
central nervous system, pupae P8
20
head, virgin 1-day female
(486)
head, virgin 4-day female
(291)
head, virgin 20-day female
(728)
head, mated 1-day female
(330)
head, mated 4-day female
(399)
head, mated 20-day female
(570)
head, mated 1-day male
(630)
head, mated 4-day male
(605)
head, mated 20-day male
(891)
salivary gland, larvae L3 wandering
19
salivary gland, white prepupae
56
digestive system, larvae L3 wandering
24
digestive system, 1-day adult
84
digestive system, 4-day adult
27
digestive system, 20-day adult
21
fat body, larvae L3 wandering
(822)
fat body, white prepupae
(611)
fat body, pupae P8
(1766)
carcass, larvae L3 wandering
23
carcass, 1-day adult
(506)
carcass, 4-day adult
(304)
carcass, 20-day adult
(400)
ovary, virgin 4-day female
1
ovary, mated 4-day female
0
testis, mated 4-day male
35
accessory gland, mated 4-day male
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
2
central nervous system, larvae L3
4
central nervous system, pupae P8
20
head, virgin 1-day female
486
head, virgin 4-day female
291
head, virgin 20-day female
728
head, mated 1-day female
330
head, mated 4-day female
399
head, mated 20-day female
570
head, mated 1-day male
630
head, mated 4-day male
605
head, mated 20-day male
891
salivary gland, larvae L3 wandering
19
salivary gland, white prepupae
56
digestive system, larvae L3 wandering
24
digestive system, 1-day adult
84
digestive system, 4-day adult
27
digestive system, 20-day adult
21
fat body, larvae L3 wandering
822
fat body, white prepupae
611
fat body, pupae P8
1766
carcass, larvae L3 wandering
23
carcass, 1-day adult
506
carcass, 4-day adult
304
carcass, 20-day adult
400
ovary, virgin 4-day female
1
ovary, mated 4-day female
0
testis, mated 4-day male
35
accessory gland, mated 4-day male
21
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
2
central nervous system, larvae L3
4
central nervous system, pupae P8
20
head, virgin 1-day female
486
head, virgin 4-day female
291
head, virgin 20-day female
728
head, mated 1-day female
330
head, mated 4-day female
399
head, mated 20-day female
570
head, mated 1-day male
630
head, mated 4-day male
605
head, mated 20-day male
891
salivary gland, larvae L3 wandering
19
salivary gland, white prepupae
56
digestive system, larvae L3 wandering
24
digestive system, 1-day adult
84
digestive system, 4-day adult
27
digestive system, 20-day adult
21
fat body, larvae L3 wandering
822
fat body, white prepupae
611
fat body, pupae P8
1766
carcass, larvae L3 wandering
23
carcass, 1-day adult
506
carcass, 4-day adult
304
carcass, 20-day adult
400
ovary, virgin 4-day female
1
ovary, mated 4-day female
0
testis, mated 4-day male
35
accessory gland, mated 4-day male
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
2
central nervous system, larvae L3
4
central nervous system, pupae P8
20
head, virgin 1-day female
(486)
head, virgin 4-day female
(291)
head, virgin 20-day female
(728)
head, mated 1-day female
(330)
head, mated 4-day female
(399)
head, mated 20-day female
(570)
head, mated 1-day male
(630)
head, mated 4-day male
(605)
head, mated 20-day male
(891)
salivary gland, larvae L3 wandering
19
salivary gland, white prepupae
(56)
digestive system, larvae L3 wandering
24
digestive system, 1-day adult
(84)
digestive system, 4-day adult
27
digestive system, 20-day adult
21
fat body, larvae L3 wandering
(822)
fat body, white prepupae
(611)
fat body, pupae P8
(1766)
carcass, larvae L3 wandering
23
carcass, 1-day adult
(506)
carcass, 4-day adult
(304)
carcass, 20-day adult
(400)
ovary, virgin 4-day female
1
ovary, mated 4-day female
0
testis, mated 4-day male
(35)
accessory gland, mated 4-day male
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
2
central nervous system, larvae L3
4
central nervous system, pupae P8
20
head, virgin 1-day female
(486)
head, virgin 4-day female
(291)
head, virgin 20-day female
(728)
head, mated 1-day female
(330)
head, mated 4-day female
(399)
head, mated 20-day female
(570)
head, mated 1-day male
(630)
head, mated 4-day male
(605)
head, mated 20-day male
(891)
salivary gland, larvae L3 wandering
19
salivary gland, white prepupae
56
digestive system, larvae L3 wandering
24
digestive system, 1-day adult
84
digestive system, 4-day adult
27
digestive system, 20-day adult
21
fat body, larvae L3 wandering
(822)
fat body, white prepupae
(611)
fat body, pupae P8
(1766)
carcass, larvae L3 wandering
23
carcass, 1-day adult
(506)
carcass, 4-day adult
(304)
carcass, 20-day adult
(400)
ovary, virgin 4-day female
1
ovary, mated 4-day female
0
testis, mated 4-day male
35
accessory gland, mated 4-day male
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
2
central nervous system, larvae L3
4
central nervous system, pupae P8
20
head, virgin 1-day female
486
head, virgin 4-day female
291
head, virgin 20-day female
728
head, mated 1-day female
330
head, mated 4-day female
399
head, mated 20-day female
570
head, mated 1-day male
630
head, mated 4-day male
605
head, mated 20-day male
891
salivary gland, larvae L3 wandering
19
salivary gland, white prepupae
56
digestive system, larvae L3 wandering
24
digestive system, 1-day adult
84
digestive system, 4-day adult
27
digestive system, 20-day adult
21
fat body, larvae L3 wandering
822
fat body, white prepupae
611
fat body, pupae P8
1766
carcass, larvae L3 wandering
23
carcass, 1-day adult
506
carcass, 4-day adult
304
carcass, 20-day adult
400
ovary, virgin 4-day female
1
ovary, mated 4-day female
0
testis, mated 4-day male
35
accessory gland, mated 4-day male
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
1
embryo 06-08hr
15
embryo 08-10hr
41
embryo 10-12hr
233
embryo 12-14hr
153
embryo 14-16hr
128
embryo 16-18hr
67
embryo 18-20hr
79
embryo 20-22hr
187
embryo 22-24hr
198
larva L1
241
larva L2
352
larva L3 12hr old
829
larva L3 puffstage 1-2
556
larva L3 puffstage 3-6
445
larva L3 puffstage 7-9
315
white prepupae new
371
white prepupae 12hr
793
white prepupae 24hr
1076
pupae 2d postWPP
1270
pupae 3d postWPP
879
pupae 4d postWPP
249
adult male 01day
933
adult male 05day
428
adult male 30day
272
adult female 01day
535
adult female 05day
215
adult female 30day
241
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
1
embryo 06-08hr
15
embryo 08-10hr
(41)
embryo 10-12hr
(233)
embryo 12-14hr
(153)
embryo 14-16hr
(128)
embryo 16-18hr
(67)
embryo 18-20hr
(79)
embryo 20-22hr
(187)
embryo 22-24hr
(198)
larva L1
(241)
larva L2
(352)
larva L3 12hr old
(829)
larva L3 puffstage 1-2
(556)
larva L3 puffstage 3-6
(445)
larva L3 puffstage 7-9
(315)
white prepupae new
(371)
white prepupae 12hr
(793)
white prepupae 24hr
(1076)
pupae 2d postWPP
(1270)
pupae 3d postWPP
(879)
pupae 4d postWPP
(249)
adult male 01day
(933)
adult male 05day
(428)
adult male 30day
(272)
adult female 01day
(535)
adult female 05day
(215)
adult female 30day
(241)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
1
embryo 06-08hr
15
embryo 08-10hr
41
embryo 10-12hr
(233)
embryo 12-14hr
(153)
embryo 14-16hr
(128)
embryo 16-18hr
67
embryo 18-20hr
79
embryo 20-22hr
(187)
embryo 22-24hr
(198)
larva L1
(241)
larva L2
(352)
larva L3 12hr old
(829)
larva L3 puffstage 1-2
(556)
larva L3 puffstage 3-6
(445)
larva L3 puffstage 7-9
(315)
white prepupae new
(371)
white prepupae 12hr
(793)
white prepupae 24hr
(1076)
pupae 2d postWPP
(1270)
pupae 3d postWPP
(879)
pupae 4d postWPP
(249)
adult male 01day
(933)
adult male 05day
(428)
adult male 30day
(272)
adult female 01day
(535)
adult female 05day
(215)
adult female 30day
(241)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
1
embryo 06-08hr
15
embryo 08-10hr
41
embryo 10-12hr
233
embryo 12-14hr
153
embryo 14-16hr
128
embryo 16-18hr
67
embryo 18-20hr
79
embryo 20-22hr
187
embryo 22-24hr
198
larva L1
241
larva L2
352
larva L3 12hr old
829
larva L3 puffstage 1-2
556
larva L3 puffstage 3-6
445
larva L3 puffstage 7-9
315
white prepupae new
371
white prepupae 12hr
793
white prepupae 24hr
1076
pupae 2d postWPP
1270
pupae 3d postWPP
879
pupae 4d postWPP
249
adult male 01day
933
adult male 05day
428
adult male 30day
272
adult female 01day
535
adult female 05day
215
adult female 30day
241
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
1
embryo 06-08hr
15
embryo 08-10hr
41
embryo 10-12hr
233
embryo 12-14hr
153
embryo 14-16hr
128
embryo 16-18hr
67
embryo 18-20hr
79
embryo 20-22hr
187
embryo 22-24hr
198
larva L1
241
larva L2
352
larva L3 12hr old
829
larva L3 puffstage 1-2
556
larva L3 puffstage 3-6
445
larva L3 puffstage 7-9
315
white prepupae new
371
white prepupae 12hr
793
white prepupae 24hr
1076
pupae 2d postWPP
1270
pupae 3d postWPP
879
pupae 4d postWPP
249
adult male 01day
933
adult male 05day
428
adult male 30day
272
adult female 01day
535
adult female 05day
215
adult female 30day
241
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
1
embryo 06-08hr
15
embryo 08-10hr
(41)
embryo 10-12hr
(233)
embryo 12-14hr
(153)
embryo 14-16hr
(128)
embryo 16-18hr
(67)
embryo 18-20hr
(79)
embryo 20-22hr
(187)
embryo 22-24hr
(198)
larva L1
(241)
larva L2
(352)
larva L3 12hr old
(829)
larva L3 puffstage 1-2
(556)
larva L3 puffstage 3-6
(445)
larva L3 puffstage 7-9
(315)
white prepupae new
(371)
white prepupae 12hr
(793)
white prepupae 24hr
(1076)
pupae 2d postWPP
(1270)
pupae 3d postWPP
(879)
pupae 4d postWPP
(249)
adult male 01day
(933)
adult male 05day
(428)
adult male 30day
(272)
adult female 01day
(535)
adult female 05day
(215)
adult female 30day
(241)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
1
embryo 06-08hr
15
embryo 08-10hr
41
embryo 10-12hr
(233)
embryo 12-14hr
(153)
embryo 14-16hr
128
embryo 16-18hr
67
embryo 18-20hr
79
embryo 20-22hr
(187)
embryo 22-24hr
(198)
larva L1
(241)
larva L2
(352)
larva L3 12hr old
(829)
larva L3 puffstage 1-2
(556)
larva L3 puffstage 3-6
(445)
larva L3 puffstage 7-9
(315)
white prepupae new
(371)
white prepupae 12hr
(793)
white prepupae 24hr
(1076)
pupae 2d postWPP
(1270)
pupae 3d postWPP
(879)
pupae 4d postWPP
(249)
adult male 01day
(933)
adult male 05day
(428)
adult male 30day
(272)
adult female 01day
(535)
adult female 05day
(215)
adult female 30day
(241)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
1
embryo 06-08hr
15
embryo 08-10hr
41
embryo 10-12hr
233
embryo 12-14hr
153
embryo 14-16hr
128
embryo 16-18hr
67
embryo 18-20hr
79
embryo 20-22hr
187
embryo 22-24hr
198
larva L1
241
larva L2
352
larva L3 12hr old
829
larva L3 puffstage 1-2
556
larva L3 puffstage 3-6
445
larva L3 puffstage 7-9
315
white prepupae new
371
white prepupae 12hr
793
white prepupae 24hr
1076
pupae 2d postWPP
1270
pupae 3d postWPP
879
pupae 4d postWPP
249
adult male 01day
933
adult male 05day
428
adult male 30day
272
adult female 01day
535
adult female 05day
215
adult female 30day
241
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
35
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
8
CNS ML-DmBG1-c1
23
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
10
ovary fGS/OSS
0
ovary OSC
0
ovary OSS
0
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
(35)
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
8
CNS ML-DmBG1-c1
23
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
10
ovary fGS/OSS
0
ovary OSC
0
ovary OSS
0
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
35
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
8
CNS ML-DmBG1-c1
23
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
10
ovary fGS/OSS
0
ovary OSC
0
ovary OSS
0
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
35
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
8
CNS ML-DmBG1-c1
23
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
10
ovary fGS/OSS
0
ovary OSC
0
ovary OSS
0
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
35
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
8
CNS ML-DmBG1-c1
23
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
10
ovary fGS/OSS
0
ovary OSC
0
ovary OSS
0
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
(35)
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
8
CNS ML-DmBG1-c1
23
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
10
ovary fGS/OSS
0
ovary OSC
0
ovary OSS
0
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
35
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
8
CNS ML-DmBG1-c1
23
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
10
ovary fGS/OSS
0
ovary OSC
0
ovary OSS
0
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
35
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
8
CNS ML-DmBG1-c1
23
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
10
ovary fGS/OSS
0
ovary OSC
0
ovary OSS
0
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
102
cold shock, 4-day adult
89
heat shock, 4-day adult
106
Cadmium 50 mM 6 hrs, larvae L3
265
Cadmium 50 mM 12 hrs, larvae L3
178
Cadmium 50 mM 48 hrs, 4-day adult
116
Cadmium 100 mM 48 hrs, 4-day adult
68
Copper 0.5 mM 12 hrs, larvae L3
84
Copper 15 mM 48 hrs, 4-day adult
32
Zinc 5 mM 12 hrs, larvae L3
59
Zinc 4.5 mM 48 hrs, 4-day adult
60
Ethanol 2.5% 3 hrs, larvae L3
83
Ethanol 5% 3 hrs, larvae L3
181
Ethanol 10% 3 hrs, larvae L3
197
Caffeine 1.5 mg/ml 4 hrs, larvae L3
164
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
120
Caffeine 25 mg/ml 48 hrs, 4-day adult
83
Paraquat 5 mM 48 hrs, 4-day adult
136
Paraquat 10 mM 48 hrs, 4-day adult
352
Rotenone 2 μg 12 hrs, larvae L3
177
Rotenone 8 μg 12 hrs, larvae L3
301
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(102)
cold shock, 4-day adult
(89)
heat shock, 4-day adult
(106)
Cadmium 50 mM 6 hrs, larvae L3
(265)
Cadmium 50 mM 12 hrs, larvae L3
(178)
Cadmium 50 mM 48 hrs, 4-day adult
(116)
Cadmium 100 mM 48 hrs, 4-day adult
(68)
Copper 0.5 mM 12 hrs, larvae L3
(84)
Copper 15 mM 48 hrs, 4-day adult
(32)
Zinc 5 mM 12 hrs, larvae L3
(59)
Zinc 4.5 mM 48 hrs, 4-day adult
(60)
Ethanol 2.5% 3 hrs, larvae L3
(83)
Ethanol 5% 3 hrs, larvae L3
(181)
Ethanol 10% 3 hrs, larvae L3
(197)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(164)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(120)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(83)
Paraquat 5 mM 48 hrs, 4-day adult
(136)
Paraquat 10 mM 48 hrs, 4-day adult
(352)
Rotenone 2 μg 12 hrs, larvae L3
(177)
Rotenone 8 μg 12 hrs, larvae L3
(301)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
102
cold shock, 4-day adult
89
heat shock, 4-day adult
106
Cadmium 50 mM 6 hrs, larvae L3
(265)
Cadmium 50 mM 12 hrs, larvae L3
(178)
Cadmium 50 mM 48 hrs, 4-day adult
(116)
Cadmium 100 mM 48 hrs, 4-day adult
68
Copper 0.5 mM 12 hrs, larvae L3
84
Copper 15 mM 48 hrs, 4-day adult
32
Zinc 5 mM 12 hrs, larvae L3
59
Zinc 4.5 mM 48 hrs, 4-day adult
60
Ethanol 2.5% 3 hrs, larvae L3
83
Ethanol 5% 3 hrs, larvae L3
(181)
Ethanol 10% 3 hrs, larvae L3
(197)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(164)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(120)
Caffeine 25 mg/ml 48 hrs, 4-day adult
83
Paraquat 5 mM 48 hrs, 4-day adult
(136)
Paraquat 10 mM 48 hrs, 4-day adult
(352)
Rotenone 2 μg 12 hrs, larvae L3
(177)
Rotenone 8 μg 12 hrs, larvae L3
(301)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
102
cold shock, 4-day adult
89
heat shock, 4-day adult
106
Cadmium 50 mM 6 hrs, larvae L3
265
Cadmium 50 mM 12 hrs, larvae L3
178
Cadmium 50 mM 48 hrs, 4-day adult
116
Cadmium 100 mM 48 hrs, 4-day adult
68
Copper 0.5 mM 12 hrs, larvae L3
84
Copper 15 mM 48 hrs, 4-day adult
32
Zinc 5 mM 12 hrs, larvae L3
59
Zinc 4.5 mM 48 hrs, 4-day adult
60
Ethanol 2.5% 3 hrs, larvae L3
83
Ethanol 5% 3 hrs, larvae L3
181
Ethanol 10% 3 hrs, larvae L3
197
Caffeine 1.5 mg/ml 4 hrs, larvae L3
164
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
120
Caffeine 25 mg/ml 48 hrs, 4-day adult
83
Paraquat 5 mM 48 hrs, 4-day adult
136
Paraquat 10 mM 48 hrs, 4-day adult
352
Rotenone 2 μg 12 hrs, larvae L3
177
Rotenone 8 μg 12 hrs, larvae L3
301
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
102
cold shock, 4-day adult
89
heat shock, 4-day adult
106
Cadmium 50 mM 6 hrs, larvae L3
265
Cadmium 50 mM 12 hrs, larvae L3
178
Cadmium 50 mM 48 hrs, 4-day adult
116
Cadmium 100 mM 48 hrs, 4-day adult
68
Copper 0.5 mM 12 hrs, larvae L3
84
Copper 15 mM 48 hrs, 4-day adult
32
Zinc 5 mM 12 hrs, larvae L3
59
Zinc 4.5 mM 48 hrs, 4-day adult
60
Ethanol 2.5% 3 hrs, larvae L3
83
Ethanol 5% 3 hrs, larvae L3
181
Ethanol 10% 3 hrs, larvae L3
197
Caffeine 1.5 mg/ml 4 hrs, larvae L3
164
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
120
Caffeine 25 mg/ml 48 hrs, 4-day adult
83
Paraquat 5 mM 48 hrs, 4-day adult
136
Paraquat 10 mM 48 hrs, 4-day adult
352
Rotenone 2 μg 12 hrs, larvae L3
177
Rotenone 8 μg 12 hrs, larvae L3
301
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(102)
cold shock, 4-day adult
(89)
heat shock, 4-day adult
(106)
Cadmium 50 mM 6 hrs, larvae L3
(265)
Cadmium 50 mM 12 hrs, larvae L3
(178)
Cadmium 50 mM 48 hrs, 4-day adult
(116)
Cadmium 100 mM 48 hrs, 4-day adult
(68)
Copper 0.5 mM 12 hrs, larvae L3
(84)
Copper 15 mM 48 hrs, 4-day adult
32
Zinc 5 mM 12 hrs, larvae L3
(59)
Zinc 4.5 mM 48 hrs, 4-day adult
(60)
Ethanol 2.5% 3 hrs, larvae L3
(83)
Ethanol 5% 3 hrs, larvae L3
(181)
Ethanol 10% 3 hrs, larvae L3
(197)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(164)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(120)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(83)
Paraquat 5 mM 48 hrs, 4-day adult
(136)
Paraquat 10 mM 48 hrs, 4-day adult
(352)
Rotenone 2 μg 12 hrs, larvae L3
(177)
Rotenone 8 μg 12 hrs, larvae L3
(301)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
102
cold shock, 4-day adult
89
heat shock, 4-day adult
106
Cadmium 50 mM 6 hrs, larvae L3
(265)
Cadmium 50 mM 12 hrs, larvae L3
(178)
Cadmium 50 mM 48 hrs, 4-day adult
116
Cadmium 100 mM 48 hrs, 4-day adult
68
Copper 0.5 mM 12 hrs, larvae L3
84
Copper 15 mM 48 hrs, 4-day adult
32
Zinc 5 mM 12 hrs, larvae L3
59
Zinc 4.5 mM 48 hrs, 4-day adult
60
Ethanol 2.5% 3 hrs, larvae L3
83
Ethanol 5% 3 hrs, larvae L3
(181)
Ethanol 10% 3 hrs, larvae L3
(197)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(164)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
120
Caffeine 25 mg/ml 48 hrs, 4-day adult
83
Paraquat 5 mM 48 hrs, 4-day adult
136
Paraquat 10 mM 48 hrs, 4-day adult
(352)
Rotenone 2 μg 12 hrs, larvae L3
(177)
Rotenone 8 μg 12 hrs, larvae L3
(301)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
102
cold shock, 4-day adult
89
heat shock, 4-day adult
106
Cadmium 50 mM 6 hrs, larvae L3
265
Cadmium 50 mM 12 hrs, larvae L3
178
Cadmium 50 mM 48 hrs, 4-day adult
116
Cadmium 100 mM 48 hrs, 4-day adult
68
Copper 0.5 mM 12 hrs, larvae L3
84
Copper 15 mM 48 hrs, 4-day adult
32
Zinc 5 mM 12 hrs, larvae L3
59
Zinc 4.5 mM 48 hrs, 4-day adult
60
Ethanol 2.5% 3 hrs, larvae L3
83
Ethanol 5% 3 hrs, larvae L3
181
Ethanol 10% 3 hrs, larvae L3
197
Caffeine 1.5 mg/ml 4 hrs, larvae L3
164
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
120
Caffeine 25 mg/ml 48 hrs, 4-day adult
83
Paraquat 5 mM 48 hrs, 4-day adult
136
Paraquat 10 mM 48 hrs, 4-day adult
352
Rotenone 2 μg 12 hrs, larvae L3
177
Rotenone 8 μg 12 hrs, larvae L3
301
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 0 ) For All Classical Alleles Show Allele of
Obp99c Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs
( 3 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions Gene Ontology: Function, Process
& Cellular Component ( 3 unique terms ) Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 3 terms ) Molecular Function inferred from sequence or structural similarity with
lush Biological Process inferred from sequence or structural similarity with
lush Cellular Component inferred from sequence model
Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
experimental knowledge based
experimental knowledge based
experimental knowledge based
experimental knowledge based
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Orthologs
OrthoDB Orthologs (20)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
No orthologs identified
Insect inclusive ortholog search
Arthropod inclusive ortholog search
No orthologs identified
Metazoa inclusive ortholog search
No orthologs identified
Orthologs in Drosophila Species
(EOG6T1J73 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects
(EOG67D8CS )
Nasonia vitripennis
Parasitic wasp
Nvit\OBP88
Y
Nasonia vitripennis
Parasitic wasp
Nvit\OBP87
Y
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG022801
Y
Tribolium castaneum
Red flour beetle
Y
Tribolium castaneum
Red flour beetle
Y
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 1 )VDRC Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 145 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for identity of: Obp99c CG7584
Source for database merge of Additional comments FlyBase curator comment: The gene referred to as "Obp99b" in
FBrf0151651 is not the same gene as the one referred to as "Obp99b" in FlyBase (
FBgn0039685 ). The gene referred to as "Obp99b" in
FBrf0151651 actually corresponds to
FBgn0039682 which is referred to in FlyBase with the symbol "Obp99c" (and corresponds to release 3 annotation CG7584).
FlyBase curator comment: The gene referred to as "Obp99b" in
FBrf0151704 is not the same gene as the one referred to as "Obp99b" in FlyBase (
FBgn0039685 ). The gene referred to as "Obp99b" in
FBrf0151704 actually corresponds to
FBgn0039682 which is referred to in FlyBase with the symbol "Obp99c" (and corresponds to release 3 annotation CG7584).
Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 6 )Reported As Symbol Synonym Obp99c
(
Wang et al., 2007 ,
Blanco et al., 2010 ,
Rollmann et al., 2007 ,
Wang et al., 2007 ,
Hsu et al., 2008 ,
Kopp et al., 2008 ,
Vieira et al., 2007 ,
Zhou et al., 2009 ,
Anholt and Williams, 2010 ,
Wang et al., 2010 ,
Japanese National Institute of Genetics, 2012.5.21 )
Name Synonym Odorant-binding protein 99c
Secondary FlyBase
IDs References ( 34 )Generate a list of List References by type
Recent research papers ( 1 )
Vieira and Rozas, 2011, Genome Biol. Evol. 3: 476--490Comparative Genomics of the Odorant-Binding and Chemosensory Protein Gene Families across the Arthropoda: Origin and Evolutionary History of the Chemosensory System. [FBrf0214323]