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Gene Dmel\neo

General Information
Symbol	Dmel\neo	Species	D. melanogaster
Name	neyo	Annotation symbol	CG7802
Feature type	protein_coding_gene	FlyBase ID	FBgn0039704
Gene Model Status	Current	Stock availability	7 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	99C2-99C2	Sequence location	3R:25,644,853..25,651,522 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene neyo is referred to in FlyBase by the symbol Dmel\neo (CG7802, FBgn0039704). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: regulation of embryonic cell shape; apical constriction. 6 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Apple-like; PAN-1 domain; Zona pellucida domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages, during early larval stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval hindgut, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1638610_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG7802. Gene sequence location is 3R:25644853..25651522.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 99C2-99C2   Limits computationally determined from genome sequence between P{PZ}ncd05884 and P{lacW}l(3)s2500s2500
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\neo for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) neo-RA FBtr0085485  NM_143476   2977   744 neo-RB FBtr0085486  NM_206583   3005   744
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein neo-PA   FBpp0084851   83.1   744   4.78     NP_651733   AAF56948 neo-PB   FBpp0084852   83.1   744   4.78     NP_996306   AAS65226
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zona pellucida domain (IPR001507) PAN-1 domain (IPR003014) Apple-like (IPR003609)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141693   AE014297 AAF56948   AE014297 AAS65226   AI062996   AI403406   AI456421   AK259741   AW941850   AY094725 AAM11078   BG638802   BI163519   BI166925   BI168500   BI170250   BI213021   BI214996   BI227918   BI228113   BI237201   BI368414   BI371209   BI371228   BI484401   BI486119   CK657745   CO274846   CO274985   CO277506   CO278615   CO280243   CO281517   CO282074   CO301811   CO302176   CO306163   CO316104   CZ475921   EC061200   EC069096   EC073288   EC073408   EC073514   EC085735   EC197482   EC203510   EC209506   EC232281   EC233921   EC234503   EC237365   EC246201   GH942885   GH945041   GH945466   GH946868   GH947339   GH948557   GH949085   GH950758   GH952593   GH959826   GH964247   GH965145   GH967257   GH968798   GH970186   GH980312   GH981409   GH982652   GH983836
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VAG2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 9 -- 10   inclusive hindgut primordium   (Fisher et al., 2012) embryonic stage 11 -- 12   anal pad primordium   (Fisher et al., 2012) Comment:reported as anal pad specific anlage foregut primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) hypopharynx proper primordium   (Fisher et al., 2012) Malpighian tubule main body primordium   (Fisher et al., 2012) Malpighian tubule primordium   (Fisher et al., 2012) stomatogastric nervous system primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic anal pad   (Fisher et al., 2012) embryonic dorsal epidermis   (Fisher et al., 2012) embryonic epipharynx   (Fisher et al., 2012) embryonic esophagus   (Fisher et al., 2012) embryonic foregut   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic hypopharynx   (Fisher et al., 2012) embryonic large intestine   (Fisher et al., 2012) embryonic Malpighian tubule   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval hindgut, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    21.875 Larval Midgut    8.2 Larval Hindgut    351.3 Larval Malpighian Tubules    7.6 Larval Fat Body    15.5 Larval Salivary Gland    7 Larval Trachea    49.8 Larval Carcass    48.225 Adult Head    13 Adult Eye    9.425 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    12.7 Adult Midgut    7.9 Adult Hindgut    6.3 Adult Malpighian Tubules    6.3 Adult Fat Body    6.1 Adult Salivary Gland    12.2 Adult Heart    3.475 Adult VirginFemale Spermatheca    5.6 Adult InseminatedFemale Spermatheca    6.6 Adult Ovary    4.1 Adult Testis    95.5 Adult Male Accessory Gland    136.6 Adult Carcass    14 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    21.875 Larval Midgut    8.2 Larval Hindgut    351.3 Larval Malpighian Tubules    7.6 Larval Fat Body    15.5 Larval Salivary Gland    7 Larval Trachea    49.8 Larval Carcass    48.225 Adult Head    13 Adult Eye    9.425 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    12.7 Adult Midgut    7.9 Adult Hindgut    6.3 Adult Malpighian Tubules    6.3 Adult Fat Body    6.1 Adult Salivary Gland    12.2 Adult Heart    3.475 Adult VirginFemale Spermatheca    5.6 Adult InseminatedFemale Spermatheca    6.6 Adult Ovary    4.1 Adult Testis    95.5 Adult Male Accessory Gland    136.6 Adult Carcass    14 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    21.875 Larval Midgut    8.2 Larval Hindgut    351.3 Larval Malpighian Tubules    7.6 Larval Fat Body    15.5 Larval Salivary Gland    7 Larval Trachea    49.8 Larval Carcass    48.225 Adult Head    13 Adult Eye    9.425 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    12.7 Adult Midgut    7.9 Adult Hindgut    6.3 Adult Malpighian Tubules    6.3 Adult Fat Body    6.1 Adult Salivary Gland    12.2 Adult Heart    3.475 Adult VirginFemale Spermatheca    5.6 Adult InseminatedFemale Spermatheca    6.6 Adult Ovary    4.1 Adult Testis    95.5 Adult Male Accessory Gland    136.6 Adult Carcass    14 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    21.875 Larval Midgut    8.2 Larval Hindgut    351.3 Larval Malpighian Tubules    7.6 Larval Fat Body    15.5 Larval Salivary Gland    7 Larval Trachea    49.8 Larval Carcass    48.225 Adult Head    13 Adult Eye    9.425 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    12.7 Adult Midgut    7.9 Adult Hindgut    6.3 Adult Malpighian Tubules    6.3 Adult Fat Body    6.1 Adult Salivary Gland    12.2 Adult Heart    3.475 Adult VirginFemale Spermatheca    5.6 Adult InseminatedFemale Spermatheca    6.6 Adult Ovary    4.1 Adult Testis    95.5 Adult Male Accessory Gland    136.6 Adult Carcass    14 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    21.875 Larval Midgut    8.2 Larval Hindgut    351.3 Larval Malpighian Tubules    7.6 Larval Fat Body    15.5 Larval Salivary Gland    7 Larval Trachea    49.8 Larval Carcass    48.225 Adult Head    13 Adult Eye    9.425 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    12.7 Adult Midgut    7.9 Adult Hindgut    6.3 Adult Malpighian Tubules    6.3 Adult Fat Body    6.1 Adult Salivary Gland    12.2 Adult Heart    3.475 Adult VirginFemale Spermatheca    5.6 Adult InseminatedFemale Spermatheca    6.6 Adult Ovary    4.1 Adult Testis    95.5 Adult Male Accessory Gland    136.6 Adult Carcass    14 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    21.875 Larval Midgut    8.2 Larval Hindgut    351.3 Larval Malpighian Tubules    7.6 Larval Fat Body    15.5 Larval Salivary Gland    7 Larval Trachea    49.8 Larval Carcass    48.225 Adult Head    13 Adult Eye    9.425 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    12.7 Adult Midgut    7.9 Adult Hindgut    6.3 Adult Malpighian Tubules    6.3 Adult Fat Body    6.1 Adult Salivary Gland    12.2 Adult Heart    3.475 Adult VirginFemale Spermatheca    5.6 Adult InseminatedFemale Spermatheca    6.6 Adult Ovary    4.1 Adult Testis    95.5 Adult Male Accessory Gland    136.6 Adult Carcass    14 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    21.875 Larval Midgut    8.2 Larval Hindgut    351.3 Larval Malpighian Tubules    7.6 Larval Fat Body    15.5 Larval Salivary Gland    7 Larval Trachea    49.8 Larval Carcass    48.225 Adult Head    13 Adult Eye    9.425 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    12.7 Adult Midgut    7.9 Adult Hindgut    6.3 Adult Malpighian Tubules    6.3 Adult Fat Body    6.1 Adult Salivary Gland    12.2 Adult Heart    3.475 Adult VirginFemale Spermatheca    5.6 Adult InseminatedFemale Spermatheca    6.6 Adult Ovary    4.1 Adult Testis    95.5 Adult Male Accessory Gland    136.6 Adult Carcass    14 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    21.875 Larval Midgut    8.2 Larval Hindgut    351.3 Larval Malpighian Tubules    7.6 Larval Fat Body    15.5 Larval Salivary Gland    7 Larval Trachea    49.8 Larval Carcass    48.225 Adult Head    13 Adult Eye    9.425 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    12.7 Adult Midgut    7.9 Adult Hindgut    6.3 Adult Malpighian Tubules    6.3 Adult Fat Body    6.1 Adult Salivary Gland    12.2 Adult Heart    3.475 Adult VirginFemale Spermatheca    5.6 Adult InseminatedFemale Spermatheca    6.6 Adult Ovary    4.1 Adult Testis    95.5 Adult Male Accessory Gland    136.6 Adult Carcass    14 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    13   NA  Eye    9.425   NA  Brain    4.4   21.875  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    7.3   NA  Crop    12.7   8.2  Midgut    7.9   351.3  Hindgut    6.3   7.6  Malpighian Tubules    6.3   no informative data  Fat Body    6.1   7  Salivary Gland    no informative data   NA  Heart    3.475   49.8  Trachea    NA   NA  VirginFemale Spermatheca    5.6   NA  InseminatedFemale Spermatheca    6.6   NA  Ovary    4.1   NA  Testis    95.5   NA  Male Accessory Gland    136.6   48.225  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    3 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    9 carcass, larvae L3 wandering    25 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (27) central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    3 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    9 carcass, larvae L3 wandering    25 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    3 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    9 carcass, larvae L3 wandering    25 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    3 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    9 carcass, larvae L3 wandering    25 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    3 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    9 carcass, larvae L3 wandering    25 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  27 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    3 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    9 carcass, larvae L3 wandering    25 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    3 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    9 carcass, larvae L3 wandering    25 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    3 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    9 carcass, larvae L3 wandering    25 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages, during early larval stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    4 embryo 06-08hr    29 embryo 08-10hr    47 embryo 10-12hr    108 embryo 12-14hr    203 embryo 14-16hr    165 embryo 16-18hr    7 embryo 18-20hr    4 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    8 larva L2    161 larva L3 12hr old    21 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    27 white prepupae new    44 white prepupae 12hr    13 white prepupae 24hr    110 pupae 2d postWPP    259 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    4 adult male 30day    4 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    4 embryo 06-08hr  (29) embryo 08-10hr  (47) embryo 10-12hr  (108) embryo 12-14hr  (203) embryo 14-16hr  (165) embryo 16-18hr    7 embryo 18-20hr    4 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    8 larva L2  (161) larva L3 12hr old    21 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9  (27) white prepupae new  (44) white prepupae 12hr    13 white prepupae 24hr  (110) pupae 2d postWPP  (259) pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    4 adult male 30day    4 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    4 embryo 06-08hr    29 embryo 08-10hr    47 embryo 10-12hr  (108) embryo 12-14hr  (203) embryo 14-16hr  (165) embryo 16-18hr    7 embryo 18-20hr    4 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    8 larva L2  (161) larva L3 12hr old    21 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    27 white prepupae new    44 white prepupae 12hr    13 white prepupae 24hr  (110) pupae 2d postWPP  (259) pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    4 adult male 30day    4 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    4 embryo 06-08hr    29 embryo 08-10hr    47 embryo 10-12hr    108 embryo 12-14hr    203 embryo 14-16hr    165 embryo 16-18hr    7 embryo 18-20hr    4 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    8 larva L2    161 larva L3 12hr old    21 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    27 white prepupae new    44 white prepupae 12hr    13 white prepupae 24hr    110 pupae 2d postWPP    259 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    4 adult male 30day    4 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    4 embryo 06-08hr    29 embryo 08-10hr    47 embryo 10-12hr    108 embryo 12-14hr    203 embryo 14-16hr    165 embryo 16-18hr    7 embryo 18-20hr    4 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    8 larva L2    161 larva L3 12hr old    21 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    27 white prepupae new    44 white prepupae 12hr    13 white prepupae 24hr    110 pupae 2d postWPP    259 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    4 adult male 30day    4 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    4 embryo 06-08hr  29 embryo 08-10hr  (47) embryo 10-12hr  (108) embryo 12-14hr  (203) embryo 14-16hr  (165) embryo 16-18hr    7 embryo 18-20hr    4 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    8 larva L2  (161) larva L3 12hr old    21 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9  27 white prepupae new  (44) white prepupae 12hr    13 white prepupae 24hr  (110) pupae 2d postWPP  (259) pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    4 adult male 30day    4 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    4 embryo 06-08hr    29 embryo 08-10hr    47 embryo 10-12hr  108 embryo 12-14hr  (203) embryo 14-16hr  (165) embryo 16-18hr    7 embryo 18-20hr    4 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    8 larva L2  (161) larva L3 12hr old    21 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    27 white prepupae new    44 white prepupae 12hr    13 white prepupae 24hr  110 pupae 2d postWPP  (259) pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    4 adult male 30day    4 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    4 embryo 06-08hr    29 embryo 08-10hr    47 embryo 10-12hr    108 embryo 12-14hr    203 embryo 14-16hr    165 embryo 16-18hr    7 embryo 18-20hr    4 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    8 larva L2    161 larva L3 12hr old    21 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    27 white prepupae new    44 white prepupae 12hr    13 white prepupae 24hr    110 pupae 2d postWPP    259 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    4 adult male 30day    4 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_07
External Data & Images
Linkouts	BDGP expression data • GH22837 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039704 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7802-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for neo Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 neoGD17223 viable neod07781 viable, with Scer\GAL4pnr-MD237 neoGD369 Sterility Allele fertile neod07781 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 neoGD17223 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 neoGD17223 trichogen cell, with Scer\GAL4pnr-MD237 neoGD17223
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of neo Class Mutagen Stocks Known lesion neod07781 P-element activity 2 -- neoMI06015 1 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of neo Class Mutagen Stocks Known lesion neoGD369 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes neoGD17223 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes neoKK111289 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes neoScer\UAS.cFa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{UAS-neo.F} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{XP}neod07781 NA miscellaneous insertions Mi{MIC}neoMI06015 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
apical constriction inferred from mutant phenotype (Fernandes et al., 2010) regulation of embryonic cell shape inferred from mutant phenotype (Fernandes et al., 2010)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
integral to membrane inferred from sequence model (Fernandes et al., 2010)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
neo - FK506-bp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) neo - flw anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions neo allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039704 DroID - A comprehensive database of gene and protein interactions. • FBgn0039704
Orthologs
OrthoDB Orthologs (31) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6256C7 Dipteran inclusive ortholog search EOG6SBF62 Insect inclusive ortholog search EOG6D51SV Arthropod inclusive ortholog search EOG6ZGMTH Metazoa inclusive ortholog search EOG61S2MT
Orthologs in Drosophila Species (EOG6256C7)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\neo     Drosophila simulans   Dsim\GD21471 Y   Drosophila sechellia   Dsec\GM12828 Y   Drosophila erecta   Dere\GG11699 Y   Drosophila yakuba   Dyak\GE23889 Y   Drosophila ananassae   Dana\GF18669 Y   Drosophila persimilis   Dper\GL14072 Y   Drosophila willistoni   Dwil\GK11653 Y   Drosophila virilis   Dvir\GJ19946 Y   Drosophila mojavensis   Dmoj\GI18984 Y   Drosophila grimshawi   Dgri\GH19413 Y
Orthologs in non-Drosophila Dipterans (EOG6SBF62)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL007579   Anopheles gambiae Malaria mosquito  Agam\AGAP002316   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ005070
Orthologs in non-Dipteran Insects (EOG6D51SV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC413256 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG011850 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21996 Y Atta cephalotes Leafcutter ant  Acep\ACEP22467 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO14689 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18606 Y Linepithema humile Argentine ant  Lhum\LH22802 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB20356 Y Solenopsis invicta Red fire ant  Sinv\SINV16441 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI009967 Y Bombyx mori Silkmoth  Bmor\BGIBMGA006371 Y Pediculus humanus Human body louse  Phum\PHUM495750 Y Tribolium castaneum Red flour beetle  Tcas\TC003763 Y
Orthologs in non-Insect Arthropods (EOG6ZGMTH)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\GBSSI Y Daphnia pulex Water flea  Dpux\ODC Y Ixodes scapularis Deer tick  Isca\ISCW001262 Y
Orthologs in non-Arthropod Metazoa (EOG61S2MT)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\cutl-28 Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD21471 Drosophila sechellia Dsec\GM12828 Drosophila erecta Dere\GG11699 Drosophila yakuba Dyak\GE23889 Drosophila ananassae Dana\GF18669 Drosophila persimilis Dper\GL14072 Drosophila willistoni Dwil\GK11653 Drosophila virilis Dvir\GJ19946 Drosophila mojavensis Dmoj\GI18984 Drosophila grimshawi Dgri\GH19413
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	19281 w1118; P{XP}neod07781 42131 y1 w*; Mi{MIC}neoMI06015
Harvard	- P{XP}neod07781
VDRC	v102265 P{KK111289}VIE-260B v33091 w1118; P{GD369}v33091 v33093 w1118; P{GD369}v33093 v46913 w1118; P{GD17223}v46913
Genomic Clones ( 2 )
	BACR02E15 BACR02O03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 64 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH22837
Other clones	DPiM_GH22837
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH02393 LP24276 RE02939 RE07171 RE09255 RE11643 RE18323 RE21173 RE25309 RE25554 RE33383 RE54379 RE58056 RE58076 RE67492 RE69504
Other clones	7072 13833 18611 39924 42287 42351 44324 55386 59123 59262 109016 147254 CK01.34A.H4 CK01.143A.E7 CK02231 EK115644 EK116120 EK125338 EK130556 EK153457 EK157346 EK159460 EK182226 EK183324 EK250411 EK263648 LD36439 RP004142727 RP004164511 RP004189364 RP004197302 RP004204608 RP004210875 RP004215780 RP004218445 RP004230613 RP004232147 RP004235119 RP004242442 RP004255518 RP004430719 RP004449945 RP004469596 RP004495143 RP004505979 RP004552549
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039704 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43523
Antibody Information
Other Information
Discoverer
Etymology
	Identified as a putative component of the matrix, and named after one of the characters in the eponymous movie. (Fernandes et al., 2010)
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: neo CG7802 (Fernandes et al., 2010)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143476 NM_206583 RefSeq (Proteins) • NP_651733 NP_996306 DDBJ / EMBL / GenBank • AAF56948 AAM11078 AAS65226 AI403406 AW941850 AY094725 CZ475921 Entrez Gene - A searchable database of RefSeq genes. • 43523 UniProtKB/TrEMBL • Q9VAG2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zona pellucida domain (IPR001507) PAN-1 domain (IPR003014) Apple-like (IPR003609) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH22837
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039704 DroID - A comprehensive database of gene and protein interactions. • FBgn0039704 DRSC - Results from RNAi screens. • FBgn0039704 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039704 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7802-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039704 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43523 modMine - Data generated by the modENCODE project. • FBgn0039704
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG7802 (Fernandes et al., 2010, Keleman et al., 2009.8.5, Fernandes et al., 2010) neo (Fernandes et al., 2010, Fernandes et al., 2010, Sienski et al., 2012)
Name Synonym	neyo (Fernandes et al., 2010, Fernandes et al., 2010)
Secondary FlyBase IDs
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 7 ) Supplementary material  ( 3 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 2 )
	Sienski et al., 2012, Cell 151(5): 964--980 Transcriptional silencing of transposons by piwi and maelstrom and its impact on chromatin state and gene expression. [FBrf0220033] Weber et al., 2012, PLoS ONE 7(4): e34745 Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster. [FBrf0218073] Show all research papers ...