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Gene Dmel\CG7816

General Information
Symbol	Dmel\CG7816	Species	D. melanogaster
Name		Annotation symbol	CG7816
Feature type	protein_coding_gene	FlyBase ID	FBgn0039714
Gene Model Status	Current	Stock availability	9 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	99C4-99C5	Sequence location	3R:25,689,423..25,694,618 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG7816 (FBgn0039714). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: metal ion transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport; metal ion transport. 6 alleles are reported. No phenotypic data is available. It has 9 annotated transcripts and 9 annotated polypeptides. Protein features are: Zinc/iron permease. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during late larval stages, during early pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval Malpighian tubules, adult male reproductive system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult female reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1630858_s_at completely aligns to an exonic region common to each of the 9 FlyBase-annotated transcript isoforms of CG7816. Gene sequence location is 3R:25689423..25694618.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 22 of adulthood day 20 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood
FB2012_01	Sequence features BKN20431 HFA16320
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 99C4-99C5   Limits computationally determined from genome sequence between P{PZ}ncd05884 and P{lacW}l(3)s2500s2500
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG7816 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	DGC clone appears problematic (GH11142): unspliced intron
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG7816-RA FBtr0089923  NM_170440   1531   355 CG7816-RC FBtr0089920  NM_170441   1570   355 CG7816-RD FBtr0089922  NM_170442   1492   355 CG7816-RE FBtr0089921  NM_170443   1533   355 CG7816-RF FBtr0089925  NM_170444   1821   355 CG7816-RG FBtr0089924  NM_170445   1539   355 CG7816-RH FBtr0303032  NM_001202384   1476   355 CG7816-RI FBtr0303033  NM_001202385   1710   355 CG7816-RJ FBtr0303034  NM_001202386   1639   355
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG7816-PA   FBpp0088862   38.9   355   4.99     NP_733319   AAN14194 CG7816-PC   FBpp0088859   38.9   355   4.99     NP_733320   AAN14195 CG7816-PD   FBpp0088861   38.9   355   4.99     NP_733321   AAN14196 CG7816-PE   FBpp0088860   38.9   355   4.99     NP_733322   AAN14197 CG7816-PF   FBpp0088864   38.9   355   4.99     NP_733323   AAN14198 CG7816-PG   FBpp0088863   38.9   355   4.99     NP_733324   AAN14199 CG7816-PH   FBpp0292151   38.9   355   4.99     NP_001189313   ADV37403 CG7816-PI   FBpp0292152   38.9   355   4.99     NP_001189314   ADV37404 CG7816-PJ   FBpp0292153   38.9   355   4.99     NP_001189315   ADV37405
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc/iron permease (IPR003689)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA391823   AA817427   AE014297 AAN14194   AE014297 AAN14195   AE014297 AAN14196   AE014297 AAN14197   AE014297 AAN14198   AE014297 AAN14199   AE014297 ADV37403   AE014297 ADV37404   AE014297 ADV37405   AI114331   AI292954   AI517353   AW940399   AY060276 AAL25315   BE976250   BF485599   BF485879   BF489096   BF489424   BF490472   BF490473   BF490489   BF490491   BF493641   BF494016   BF494424   BF497803   BF498733   BF499330   BF500462   BF501468   BF501714   BF501927   BF504673   BG632197   BG633488   BG635028   BI229585   BI234683   BI235653   BI236036   BI366993   BI371044   BI373021   BI375110   BI482537   BI569126   BI569127   BI569228   BI569229   BI608810   BI610447   BI611408   BI614638   BI619657   BI628606   BI628853   BI636418   BT001774 AAN71529   CO154962   CO156977   CO179326   CO183713   CO183716   CO187640   CO299481   CO307277   CO317445   CO336089   CO336299   CO338287   CO338824   CO340411   CO344790   CZ485430   CZ485431   CZ487830   EC052890   EC053381   EC053405   EC053850   EC054249   EC054345   EC054873   EC055213   EC069133   EC069283   EC069866   EC074592   EC088987   EC199718   EC249854   EC259694   EC261036   EC263217   EC263483   EC264181   EV586408   EV590140   EV596502
UniProtKB/Swiss-Prot	Q9VAF0
UniProtKB/TrEMBL	Q95T93 A4V3L8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039714    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039714 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during late larval stages, during early pupal stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039714 expression level Developmental Stage   Expression Level embryo 00-02hr    2076 embryo 02-04hr    681 embryo 04-06hr    906 embryo 06-08hr    1504 embryo 08-10hr    1465 embryo 10-12hr    2205 embryo 12-14hr    1568 embryo 14-16hr    777 embryo 16-18hr    904 embryo 18-20hr    1365 embryo 20-22hr    1764 embryo 22-24hr    1679 larva L1    1011 larva L2    804 larva L3 12hr old    1027 larva L3 puffstage 1-2    2824 larva L3 puffstage 3-6    5874 larva L3 puffstage 7-9    8027 white prepupae new    6139 white prepupae 12hr    2891 white prepupae 24hr    2522 pupae 2d postWPP    2518 pupae 3d postWPP    2189 pupae 4d postWPP    2089 adult male 01day    3980 adult male 05day    4917 adult male 30day    4251 adult female 01day    1964 adult female 05day    2528 adult female 30day    2989 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2076) embryo 02-04hr  (681) embryo 04-06hr  (906) embryo 06-08hr  (1504) embryo 08-10hr  (1465) embryo 10-12hr  (2205) embryo 12-14hr  (1568) embryo 14-16hr  (777) embryo 16-18hr  (904) embryo 18-20hr  (1365) embryo 20-22hr  (1764) embryo 22-24hr  (1679) larva L1  (1011) larva L2  (804) larva L3 12hr old  (1027) larva L3 puffstage 1-2  (2824) larva L3 puffstage 3-6  (5874) larva L3 puffstage 7-9  (8027) white prepupae new  (6139) white prepupae 12hr  (2891) white prepupae 24hr  (2522) pupae 2d postWPP  (2518) pupae 3d postWPP  (2189) pupae 4d postWPP  (2089) adult male 01day  (3980) adult male 05day  (4917) adult male 30day  (4251) adult female 01day  (1964) adult female 05day  (2528) adult female 30day  (2989) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2076) embryo 02-04hr    681 embryo 04-06hr    906 embryo 06-08hr  1504 embryo 08-10hr  1465 embryo 10-12hr  (2205) embryo 12-14hr  (1568) embryo 14-16hr    777 embryo 16-18hr    904 embryo 18-20hr    1365 embryo 20-22hr  (1764) embryo 22-24hr  (1679) larva L1    1011 larva L2    804 larva L3 12hr old    1027 larva L3 puffstage 1-2  (2824) larva L3 puffstage 3-6  (5874) larva L3 puffstage 7-9  (8027) white prepupae new  (6139) white prepupae 12hr  (2891) white prepupae 24hr  (2522) pupae 2d postWPP  (2518) pupae 3d postWPP  (2189) pupae 4d postWPP  (2089) adult male 01day  (3980) adult male 05day  (4917) adult male 30day  (4251) adult female 01day  (1964) adult female 05day  (2528) adult female 30day  (2989) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2076 embryo 02-04hr    681 embryo 04-06hr    906 embryo 06-08hr    1504 embryo 08-10hr    1465 embryo 10-12hr    2205 embryo 12-14hr    1568 embryo 14-16hr    777 embryo 16-18hr    904 embryo 18-20hr    1365 embryo 20-22hr    1764 embryo 22-24hr    1679 larva L1    1011 larva L2    804 larva L3 12hr old    1027 larva L3 puffstage 1-2    2824 larva L3 puffstage 3-6    5874 larva L3 puffstage 7-9    8027 white prepupae new    6139 white prepupae 12hr    2891 white prepupae 24hr    2522 pupae 2d postWPP    2518 pupae 3d postWPP    2189 pupae 4d postWPP    2089 adult male 01day    3980 adult male 05day    4917 adult male 30day    4251 adult female 01day    1964 adult female 05day    2528 adult female 30day    2989 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2076 embryo 02-04hr    681 embryo 04-06hr    906 embryo 06-08hr    1504 embryo 08-10hr    1465 embryo 10-12hr    2205 embryo 12-14hr    1568 embryo 14-16hr    777 embryo 16-18hr    904 embryo 18-20hr    1365 embryo 20-22hr    1764 embryo 22-24hr    1679 larva L1    1011 larva L2    804 larva L3 12hr old    1027 larva L3 puffstage 1-2    2824 larva L3 puffstage 3-6    5874 larva L3 puffstage 7-9    8027 white prepupae new    6139 white prepupae 12hr    2891 white prepupae 24hr    2522 pupae 2d postWPP    2518 pupae 3d postWPP    2189 pupae 4d postWPP    2089 adult male 01day    3980 adult male 05day    4917 adult male 30day    4251 adult female 01day    1964 adult female 05day    2528 adult female 30day    2989 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039714 expression level Developmental Stage   Expression Level embryo 00-02hr    2076 embryo 02-04hr    681 embryo 04-06hr    906 embryo 06-08hr    1504 embryo 08-10hr    1465 embryo 10-12hr    2205 embryo 12-14hr    1568 embryo 14-16hr    777 embryo 16-18hr    904 embryo 18-20hr    1365 embryo 20-22hr    1764 embryo 22-24hr    1679 larva L1    1011 larva L2    804 larva L3 12hr old    1027 larva L3 puffstage 1-2    2824 larva L3 puffstage 3-6    5874 larva L3 puffstage 7-9    8027 white prepupae new    6139 white prepupae 12hr    2891 white prepupae 24hr    2522 pupae 2d postWPP    2518 pupae 3d postWPP    2189 pupae 4d postWPP    2089 adult male 01day    3980 adult male 05day    4917 adult male 30day    4251 adult female 01day    1964 adult female 05day    2528 adult female 30day    2989 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2076) embryo 02-04hr  (681) embryo 04-06hr  (906) embryo 06-08hr  (1504) embryo 08-10hr  (1465) embryo 10-12hr  (2205) embryo 12-14hr  (1568) embryo 14-16hr  (777) embryo 16-18hr  (904) embryo 18-20hr  (1365) embryo 20-22hr  (1764) embryo 22-24hr  (1679) larva L1  (1011) larva L2  (804) larva L3 12hr old  (1027) larva L3 puffstage 1-2  (2824) larva L3 puffstage 3-6  (5874) larva L3 puffstage 7-9  (8027) white prepupae new  (6139) white prepupae 12hr  (2891) white prepupae 24hr  (2522) pupae 2d postWPP  (2518) pupae 3d postWPP  (2189) pupae 4d postWPP  (2089) adult male 01day  (3980) adult male 05day  (4917) adult male 30day  (4251) adult female 01day  (1964) adult female 05day  (2528) adult female 30day  (2989) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  2076 embryo 02-04hr    681 embryo 04-06hr    906 embryo 06-08hr  1504 embryo 08-10hr  1465 embryo 10-12hr  2205 embryo 12-14hr  1568 embryo 14-16hr    777 embryo 16-18hr    904 embryo 18-20hr    1365 embryo 20-22hr  1764 embryo 22-24hr  1679 larva L1    1011 larva L2    804 larva L3 12hr old    1027 larva L3 puffstage 1-2  (2824) larva L3 puffstage 3-6  (5874) larva L3 puffstage 7-9  (8027) white prepupae new  (6139) white prepupae 12hr  (2891) white prepupae 24hr  (2522) pupae 2d postWPP  (2518) pupae 3d postWPP  2189 pupae 4d postWPP  2089 adult male 01day  (3980) adult male 05day  (4917) adult male 30day  (4251) adult female 01day  1964 adult female 05day  (2528) adult female 30day  (2989) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2076 embryo 02-04hr    681 embryo 04-06hr    906 embryo 06-08hr    1504 embryo 08-10hr    1465 embryo 10-12hr    2205 embryo 12-14hr    1568 embryo 14-16hr    777 embryo 16-18hr    904 embryo 18-20hr    1365 embryo 20-22hr    1764 embryo 22-24hr    1679 larva L1    1011 larva L2    804 larva L3 12hr old    1027 larva L3 puffstage 1-2    2824 larva L3 puffstage 3-6    5874 larva L3 puffstage 7-9    8027 white prepupae new    6139 white prepupae 12hr    2891 white prepupae 24hr    2522 pupae 2d postWPP    2518 pupae 3d postWPP    2189 pupae 4d postWPP    2089 adult male 01day    3980 adult male 05day    4917 adult male 30day    4251 adult female 01day    1964 adult female 05day    2528 adult female 30day    2989 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2076 embryo 02-04hr    681 embryo 04-06hr    906 embryo 06-08hr    1504 embryo 08-10hr    1465 embryo 10-12hr    2205 embryo 12-14hr    1568 embryo 14-16hr    777 embryo 16-18hr    904 embryo 18-20hr    1365 embryo 20-22hr    1764 embryo 22-24hr    1679 larva L1    1011 larva L2    804 larva L3 12hr old    1027 larva L3 puffstage 1-2    2824 larva L3 puffstage 3-6    5874 larva L3 puffstage 7-9    8027 white prepupae new    6139 white prepupae 12hr    2891 white prepupae 24hr    2522 pupae 2d postWPP    2518 pupae 3d postWPP    2189 pupae 4d postWPP    2089 adult male 01day    3980 adult male 05day    4917 adult male 30day    4251 adult female 01day    1964 adult female 05day    2528 adult female 30day    2989 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0039714    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0039714 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval Malpighian tubules, adult male reproductive system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult female reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0039714 expression level Tissue   Expression Level Larval Central Nervous System    66.775 Larval Midgut    1308.5 Larval Hindgut    312.2 Larval Malpighian Tubules    558.1 Larval Fat Body    191.9 Larval Salivary Gland    82 Larval Trachea    94.5 Larval Carcass    164.95 Adult Head    195.7 Adult Eye    136.375 Adult Brain    159 Adult Thoracic-Abdominal Ganglion    135 Adult Crop    172.4 Adult Midgut    839.4 Adult Hindgut    243.9 Adult Malpighian Tubules    401.7 Adult Fat Body    301.1 Adult Salivary Gland    143.7 Adult Heart    496.125 Adult VirginFemale Spermatheca    253.1 Adult InseminatedFemale Spermatheca    257 Adult Ovary    245 Adult Testis    900.4 Adult Male Accessory Gland    508.4 Adult Carcass    253.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    66.775 Larval Midgut  (1308.5) Larval Hindgut    312.2 Larval Malpighian Tubules  (558.1) Larval Fat Body    191.9 Larval Salivary Gland    82 Larval Trachea    94.5 Larval Carcass    164.95 Adult Head    195.7 Adult Eye    136.375 Adult Brain    159 Adult Thoracic-Abdominal Ganglion    135 Adult Crop    172.4 Adult Midgut  (839.4) Adult Hindgut    243.9 Adult Malpighian Tubules    401.7 Adult Fat Body    301.1 Adult Salivary Gland    143.7 Adult Heart    496.125 Adult VirginFemale Spermatheca    253.1 Adult InseminatedFemale Spermatheca    257 Adult Ovary    245 Adult Testis  (900.4) Adult Male Accessory Gland  508.4 Adult Carcass    253.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    66.775 Larval Midgut  (1308.5) Larval Hindgut    312.2 Larval Malpighian Tubules    558.1 Larval Fat Body    191.9 Larval Salivary Gland    82 Larval Trachea    94.5 Larval Carcass    164.95 Adult Head    195.7 Adult Eye    136.375 Adult Brain    159 Adult Thoracic-Abdominal Ganglion    135 Adult Crop    172.4 Adult Midgut    839.4 Adult Hindgut    243.9 Adult Malpighian Tubules    401.7 Adult Fat Body    301.1 Adult Salivary Gland    143.7 Adult Heart    496.125 Adult VirginFemale Spermatheca    253.1 Adult InseminatedFemale Spermatheca    257 Adult Ovary    245 Adult Testis    900.4 Adult Male Accessory Gland    508.4 Adult Carcass    253.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    66.775 Larval Midgut    1308.5 Larval Hindgut    312.2 Larval Malpighian Tubules    558.1 Larval Fat Body    191.9 Larval Salivary Gland    82 Larval Trachea    94.5 Larval Carcass    164.95 Adult Head    195.7 Adult Eye    136.375 Adult Brain    159 Adult Thoracic-Abdominal Ganglion    135 Adult Crop    172.4 Adult Midgut    839.4 Adult Hindgut    243.9 Adult Malpighian Tubules    401.7 Adult Fat Body    301.1 Adult Salivary Gland    143.7 Adult Heart    496.125 Adult VirginFemale Spermatheca    253.1 Adult InseminatedFemale Spermatheca    257 Adult Ovary    245 Adult Testis    900.4 Adult Male Accessory Gland    508.4 Adult Carcass    253.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0039714 expression level Tissue   Expression Level Larval Central Nervous System    66.775 Larval Midgut    1308.5 Larval Hindgut    312.2 Larval Malpighian Tubules    558.1 Larval Fat Body    191.9 Larval Salivary Gland    82 Larval Trachea    94.5 Larval Carcass    164.95 Adult Head    195.7 Adult Eye    136.375 Adult Brain    159 Adult Thoracic-Abdominal Ganglion    135 Adult Crop    172.4 Adult Midgut    839.4 Adult Hindgut    243.9 Adult Malpighian Tubules    401.7 Adult Fat Body    301.1 Adult Salivary Gland    143.7 Adult Heart    496.125 Adult VirginFemale Spermatheca    253.1 Adult InseminatedFemale Spermatheca    257 Adult Ovary    245 Adult Testis    900.4 Adult Male Accessory Gland    508.4 Adult Carcass    253.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    66.775 Larval Midgut  (1308.5) Larval Hindgut    312.2 Larval Malpighian Tubules  558.1 Larval Fat Body    191.9 Larval Salivary Gland    82 Larval Trachea    94.5 Larval Carcass    164.95 Adult Head    195.7 Adult Eye    136.375 Adult Brain    159 Adult Thoracic-Abdominal Ganglion    135 Adult Crop    172.4 Adult Midgut  (839.4) Adult Hindgut    243.9 Adult Malpighian Tubules    401.7 Adult Fat Body    301.1 Adult Salivary Gland    143.7 Adult Heart    496.125 Adult VirginFemale Spermatheca    253.1 Adult InseminatedFemale Spermatheca    257 Adult Ovary    245 Adult Testis  (900.4) Adult Male Accessory Gland  508.4 Adult Carcass    253.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    66.775 Larval Midgut  1308.5 Larval Hindgut    312.2 Larval Malpighian Tubules    558.1 Larval Fat Body    191.9 Larval Salivary Gland    82 Larval Trachea    94.5 Larval Carcass    164.95 Adult Head    195.7 Adult Eye    136.375 Adult Brain    159 Adult Thoracic-Abdominal Ganglion    135 Adult Crop    172.4 Adult Midgut    839.4 Adult Hindgut    243.9 Adult Malpighian Tubules    401.7 Adult Fat Body    301.1 Adult Salivary Gland    143.7 Adult Heart    496.125 Adult VirginFemale Spermatheca    253.1 Adult InseminatedFemale Spermatheca    257 Adult Ovary    245 Adult Testis    900.4 Adult Male Accessory Gland    508.4 Adult Carcass    253.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    66.775 Larval Midgut    1308.5 Larval Hindgut    312.2 Larval Malpighian Tubules    558.1 Larval Fat Body    191.9 Larval Salivary Gland    82 Larval Trachea    94.5 Larval Carcass    164.95 Adult Head    195.7 Adult Eye    136.375 Adult Brain    159 Adult Thoracic-Abdominal Ganglion    135 Adult Crop    172.4 Adult Midgut    839.4 Adult Hindgut    243.9 Adult Malpighian Tubules    401.7 Adult Fat Body    301.1 Adult Salivary Gland    143.7 Adult Heart    496.125 Adult VirginFemale Spermatheca    253.1 Adult InseminatedFemale Spermatheca    257 Adult Ovary    245 Adult Testis    900.4 Adult Male Accessory Gland    508.4 Adult Carcass    253.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    195.7   NA  Eye    136.375   NA  Brain    159   66.775  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    135   NA  Crop    172.4   1308.5  Midgut    839.4   312.2  Hindgut    243.9   558.1  Malpighian Tubules    401.7   191.9  Fat Body    301.1   82  Salivary Gland    143.7   NA  Heart    496.125   94.5  Trachea    NA   NA  VirginFemale Spermatheca    253.1   NA  InseminatedFemale Spermatheca    257   NA  Ovary    245   NA  Testis    900.4   NA  Male Accessory Gland    508.4   164.95  Carcass    253.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_04
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039714 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7816-RF FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG7816 Stages(s) 1-3 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG7816GD370 Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of CG7816 Class Mutagen Stocks Known lesion CG7816f00306 piggyBac transposase 2 -- CG7816f02876 piggyBac transposase 2 -- CG78163 P-element activity 1 Yes CG7816f05205 piggyBac transposase 1 -- CG7816MB00749 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG7816 Class Mutagen Stocks Known lesion CG7816GD370 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD370} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SRS3.9}CG78163 NA PBac{WH}CG7816f00306 NA PBac{WH}CG7816f02876 NA PBac{WH}CG7816f05205 NA insertion of enhancer trap binary system Mi{ET1}CG7816MB00749 No
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
metal ion transmembrane transporter activity inferred from electronic annotation with InterPro:IPR003689 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
metal ion transport inferred from electronic annotation with InterPro:IPR003689 (FlyBase Curators et al., 2004-) transmembrane transport inferred from electronic annotation with InterPro:IPR003689 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane non-traceable author statement (Swiss-Prot Project Members, 2000.10.1) membrane inferred from electronic annotation with InterPro:IPR003689 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG7816 allele Gene References CG78163 piwi (Smulders-Srinivasan and Lin, 2003)
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039714 DroID - A comprehensive database of gene and protein interactions. • FBgn0039714
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16226 Dere\GG11991 Dgri\GH13993 Dmoj\GI22338 Dper\GL13475 Dpse\GA20606 Dsec\GM12209 Dsim\GD17600 Dvir\GJ10525 Dwil\GK13376 Dyak\GE10416
Curated drosophilid orthologs	Dpse\GA20606
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL014762-PA Aedes aegypti (mosquito) AGAP003300-PA Anopheles gambiae (mosquito) XP_395608.2 Apis mellifera (honey bee) XP_001949211.1 Acyrthosiphon pisum (pea aphid) 126133 Branchiostoma floridae (lancelet) BGIBMGA002345-PA Bombyx mori (silk worm) ENSBTAP00000047569 Bos taurus (bovine) ENSCAFP00000012813 Canis familiaris (dog) CPIJ001666 Culex pipens (mosquito) ENSCPOP00000007346 Cavia porcellus (guinea pig) RP41896 Caenorhabditis remanei (nematode) ENSCSAVP00000011853 Ciona savignyi (sedentary tunicate) 94046 Capitella spl (polychaete worm) 40908 Daphnia pulex (daphnia) ENSDARP00000018718 Danio rerio (zebra fish) ENSECAP00000022138 Equus caballus (horse) ENSGACP00000020491 Gymnopilus aculeatus (mushroom) ENSGALP00000013168 Gallus gallus (chicken) ENSP00000346956 Homo sapiens (human) ISCW008437-PA Ixodes scapularis (deer tick) 30267 Monocosta brevicollis (choanoflagellate) ENSMODP00000024838 Monodelphis domestica (gray opossum) ENSMMUP00000020480 Macaca mulatta (rhesus monkey) ENSMUSP00000107063 Mus musculus (house mouse) XP_001606497.1 Nasonia vitripennis (wasp) ENSOANP00000012563 Ornithorynchus anatinus (platypus) ENSORLP00000007669 Oryzias latipes (japanese killifish) PHUM002580-PA Pediculus humanus (human body louse) ENSPPYP00000003792 Pongo pygmaeus (orangutan) ENSPTRP00000041029 Pan troglodytes (chimpanzee) ENSRNOP00000016191 Rattus norvegicus (norway rat) Smp_166790 Schistosoma mansoni (trematode parasite) XP_789019.2 Strongylocentrotus purpuratus (purple sea urchin) 50931 Trichoplax adhaerens (metazoa) XP_975125.1 Tribolium castaneum (red flour beetle) ENSTNIP00000012276 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000044253 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000017360 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15251 NV11516 LH11277 ISCW008437 FBgn0228280 FBgn0215385 FBgn0197805 FBgn0189150 FBgn0167146 JGI_V11_40908 FBgn0080600 FBgn0151081 FBgn0145066 FBgn0121469 FBgn0104283 FBgn0093248 CPIJ001666 BGIBMGA002345 ACYPI009406 GB12620 AGAP003300 AAEL014762 PHUM433950 GLEAN_12751
Stocks & Reagents
Stocks Listed in FlyBase ( 9 )
Bloomington	10395 ry506 P{SRS3.9}CG78163 18311 w1118; PBac{WH}CG7816f00306 22890 y1 w67c23; Mi{ET1}CG7816MB00749 18595 w1118; PBac{WH}CG7816f02876/TM6B, Tb1
Harvard	- PBac{WH}CG7816f00306 - PBac{WH}CG7816f02876 - PBac{WH}CG7816f05205
VDRC	v1362 w1118; P{GD370}v1362 v1364 w1118; P{GD370}v1364
Genomic Clones ( 1 )
	BACR02E15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 85 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH11142 RH13513
Other clones	DPiM_RH13513
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT01957 AT02419 AT03018 AT06275 AT12102 AT13196 AT13866 AT15415 AT16818 AT17513 AT19526 AT19953 AT24796 AT25542 AT26948 AT26949 AT26970 AT26972 AT31480 GH04969 GH15993 LD10747 LD22827 RE27395 RE30430 RE31557 RE32023 RE52653 RE57853 RE60233 RE62845 RE65238 RH15936 RH17611 RH44069 RH50734 RH57091 RH57613 SD18096
Other clones	47519 63436 149079 161640 214413.1 524285 556979 557713 571233 AT17205 bs48e12 CK01.36B.A10 CK01.49A.F9 CK01.75C.F5 Dmel_neb_012223_0873_1093 Dmel_neb_014374_0112_1289 Dmel_neb_014838_0325_1961 EC26183 EC26190 EC052890 EC053381 EC053405 EC053850 EC054249 EC054345 EC054873 EC055213 EK031026 EK059123 EK175534 EK254251 EK268061 EN05115 EN09704 EN11812 EN12242 EN16413 EN17702 EP10602 EP19910 GH28072 RH01308 RH01368
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039714 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43533
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_170440 NM_170441 NM_170442 NM_170443 NM_170444 NM_170445 NM_001202384 NM_001202385 NM_001202386 RefSeq (Proteins) • NP_733319 NP_733320 NP_733321 NP_733322 NP_733323 NP_733324 NP_001189313 NP_001189314 NP_001189315 DDBJ / EMBL / GenBank • AAL25315 AAN14194 AAN14195 AAN14196 AAN14197 AAN14198 AAN14199 AAN71529 ADV37403 ADV37404 ADV37405 AI114331 AW940399 AY060276 BI608810 BT001774 CZ485430 CZ485431 CZ487830 Entrez Gene - A searchable database of RefSeq genes. • 43533 UniProtKB/Swiss-Prot • Q9VAF0 UniProtKB/TrEMBL • A4V3L8 Q95T93
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc/iron permease (IPR003689)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039714 DroID - A comprehensive database of gene and protein interactions. • FBgn0039714 DRSC - Results from RNAi screens. • FBgn0039714 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039714 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7816-RF FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039714 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43533 InParanoid A subset of ortholog calls from InParanoid. • AAEL014762-PA Aedes aegypti (mosquito) AGAP003300-PA Anopheles gambiae (mosquito) XP_395608.2 Apis mellifera (honey bee) XP_001949211.1 Acyrthosiphon pisum (pea aphid) 126133 Branchiostoma floridae (lancelet) BGIBMGA002345-PA Bombyx mori (silk worm) ENSBTAP00000047569 Bos taurus (bovine) ENSCAFP00000012813 Canis familiaris (dog) CPIJ001666 Culex pipens (mosquito) ENSCPOP00000007346 Cavia porcellus (guinea pig) RP41896 Caenorhabditis remanei (nematode) ENSCSAVP00000011853 Ciona savignyi (sedentary tunicate) 94046 Capitella spl (polychaete worm) 40908 Daphnia pulex (daphnia) ENSDARP00000018718 Danio rerio (zebra fish) ENSECAP00000022138 Equus caballus (horse) ENSGACP00000020491 Gymnopilus aculeatus (mushroom) ENSGALP00000013168 Gallus gallus (chicken) ENSP00000346956 Homo sapiens (human) ISCW008437-PA Ixodes scapularis (deer tick) 30267 Monocosta brevicollis (choanoflagellate) ENSMODP00000024838 Monodelphis domestica (gray opossum) ENSMMUP00000020480 Macaca mulatta (rhesus monkey) ENSMUSP00000107063 Mus musculus (house mouse) XP_001606497.1 Nasonia vitripennis (wasp) ENSOANP00000012563 Ornithorynchus anatinus (platypus) ENSORLP00000007669 Oryzias latipes (japanese killifish) PHUM002580-PA Pediculus humanus (human body louse) ENSPPYP00000003792 Pongo pygmaeus (orangutan) ENSPTRP00000041029 Pan troglodytes (chimpanzee) ENSRNOP00000016191 Rattus norvegicus (norway rat) Smp_166790 Schistosoma mansoni (trematode parasite) XP_789019.2 Strongylocentrotus purpuratus (purple sea urchin) 50931 Trichoplax adhaerens (metazoa) XP_975125.1 Tribolium castaneum (red flour beetle) ENSTNIP00000012276 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000044253 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000017360 Xenopus tropicalis (frog) modMine - Data generated by the modENCODE project. • FBgn0039714 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15251 NV11516 LH11277 ISCW008437 FBgn0228280 FBgn0215385 FBgn0197805 FBgn0189150 FBgn0167146 JGI_V11_40908 FBgn0080600 FBgn0151081 FBgn0145066 FBgn0121469 FBgn0104283 FBgn0093248 CPIJ001666 BGIBMGA002345 ACYPI009406 GB12620 AGAP003300 AAEL014762 PHUM433950 GLEAN_12751
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG7816 (Lebo et al., 2009, Kim et al., 2005, Cammarato et al., 2011)
Name Synonym
Secondary FlyBase IDs
References ( 17 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Lebo et al., 2009, BMC Genomics 10: 80 Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis. [FBrf0207472] Kim et al., 2005, Nature Immunology 6(2): 211--218 Downregulation of lipopolysaccharide response in Drosophila by negative crosstalk between the AP1 and NF-kappaB signaling modules. [FBrf0184193] Smulders-Srinivasan and Lin, 2003, Genetics 165(4): 1971--1991 Screens for piwi suppressors in Drosophila identify dosage-dependent regulators of germline stem cell division. [FBrf0167655]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bellen, 2006.11.6, Batch702.xml Batch702.xml [FBrf0191798] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
Protein sequence record	Swiss-Prot Project Members, 2000.10.1, UniProtKB: Q9VAF0 HYPOTHETIAL PROTEIN CG7816. [FBrf0136208]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]