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Gene Dmel\CG15525

General Information
Symbol	Dmel\CG15525	Species	D. melanogaster
Name		Annotation symbol	CG15525
Feature type	protein_coding_gene	FlyBase ID	FBgn0039732
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	99D1-99D1	Sequence location	3R:25,822,683..25,823,398 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG15525 (FBgn0039732). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: mRNA splicing factor, Cwf18. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1631208_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG15525. Gene sequence location is 3R:25822683..25823398.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 99D1-99D1   Limits computationally determined from genome sequence between P{PZ}ncd05884 and P{lacW}l(3)s2500s2500
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG15525 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG15525-RA FBtr0085607  NM_143500   654   161
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG15525-PA   FBpp0084929   18.3   161   4.84     NP_651757   AAF56984
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • mRNA splicing factor, Cwf18 (IPR013169)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF56984   AY119262 AAM51122   BI640401   BP543185   BP543186   BT081396   CO336046   CO341227   EC064030   EC254714   EC261396   EV585635
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VAC7 Q8MRU7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    128.775 Larval Midgut    46.4 Larval Hindgut    54.5 Larval Malpighian Tubules    78.1 Larval Fat Body    76.1 Larval Salivary Gland    81.1 Larval Trachea    98.55 Larval Carcass    59.3 Adult Head    68.1 Adult Eye    107.225 Adult Brain    84.7 Adult Thoracic-Abdominal Ganglion    84.1 Adult Crop    78.2 Adult Midgut    38.6 Adult Hindgut    61.8 Adult Malpighian Tubules    28.7 Adult Fat Body    54.7 Adult Salivary Gland    96.4 Adult Heart    73.85 Adult VirginFemale Spermatheca    63.5 Adult InseminatedFemale Spermatheca    54.8 Adult Ovary    152 Adult Testis    63.1 Adult Male Accessory Gland    79.8 Adult Carcass    69.1 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    128.775 Larval Midgut    46.4 Larval Hindgut    54.5 Larval Malpighian Tubules    78.1 Larval Fat Body    76.1 Larval Salivary Gland    81.1 Larval Trachea    98.55 Larval Carcass    59.3 Adult Head    68.1 Adult Eye    107.225 Adult Brain    84.7 Adult Thoracic-Abdominal Ganglion    84.1 Adult Crop    78.2 Adult Midgut    38.6 Adult Hindgut    61.8 Adult Malpighian Tubules    28.7 Adult Fat Body    54.7 Adult Salivary Gland    96.4 Adult Heart    73.85 Adult VirginFemale Spermatheca    63.5 Adult InseminatedFemale Spermatheca    54.8 Adult Ovary    152 Adult Testis    63.1 Adult Male Accessory Gland    79.8 Adult Carcass    69.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    128.775 Larval Midgut    46.4 Larval Hindgut    54.5 Larval Malpighian Tubules    78.1 Larval Fat Body    76.1 Larval Salivary Gland    81.1 Larval Trachea    98.55 Larval Carcass    59.3 Adult Head    68.1 Adult Eye    107.225 Adult Brain    84.7 Adult Thoracic-Abdominal Ganglion    84.1 Adult Crop    78.2 Adult Midgut    38.6 Adult Hindgut    61.8 Adult Malpighian Tubules    28.7 Adult Fat Body    54.7 Adult Salivary Gland    96.4 Adult Heart    73.85 Adult VirginFemale Spermatheca    63.5 Adult InseminatedFemale Spermatheca    54.8 Adult Ovary    152 Adult Testis    63.1 Adult Male Accessory Gland    79.8 Adult Carcass    69.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    128.775 Larval Midgut    46.4 Larval Hindgut    54.5 Larval Malpighian Tubules    78.1 Larval Fat Body    76.1 Larval Salivary Gland    81.1 Larval Trachea    98.55 Larval Carcass    59.3 Adult Head    68.1 Adult Eye    107.225 Adult Brain    84.7 Adult Thoracic-Abdominal Ganglion    84.1 Adult Crop    78.2 Adult Midgut    38.6 Adult Hindgut    61.8 Adult Malpighian Tubules    28.7 Adult Fat Body    54.7 Adult Salivary Gland    96.4 Adult Heart    73.85 Adult VirginFemale Spermatheca    63.5 Adult InseminatedFemale Spermatheca    54.8 Adult Ovary    152 Adult Testis    63.1 Adult Male Accessory Gland    79.8 Adult Carcass    69.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    128.775 Larval Midgut    46.4 Larval Hindgut    54.5 Larval Malpighian Tubules    78.1 Larval Fat Body    76.1 Larval Salivary Gland    81.1 Larval Trachea    98.55 Larval Carcass    59.3 Adult Head    68.1 Adult Eye    107.225 Adult Brain    84.7 Adult Thoracic-Abdominal Ganglion    84.1 Adult Crop    78.2 Adult Midgut    38.6 Adult Hindgut    61.8 Adult Malpighian Tubules    28.7 Adult Fat Body    54.7 Adult Salivary Gland    96.4 Adult Heart    73.85 Adult VirginFemale Spermatheca    63.5 Adult InseminatedFemale Spermatheca    54.8 Adult Ovary    152 Adult Testis    63.1 Adult Male Accessory Gland    79.8 Adult Carcass    69.1 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    128.775 Larval Midgut    46.4 Larval Hindgut    54.5 Larval Malpighian Tubules    78.1 Larval Fat Body    76.1 Larval Salivary Gland    81.1 Larval Trachea    98.55 Larval Carcass    59.3 Adult Head    68.1 Adult Eye    107.225 Adult Brain    84.7 Adult Thoracic-Abdominal Ganglion    84.1 Adult Crop    78.2 Adult Midgut    38.6 Adult Hindgut    61.8 Adult Malpighian Tubules    28.7 Adult Fat Body    54.7 Adult Salivary Gland    96.4 Adult Heart    73.85 Adult VirginFemale Spermatheca    63.5 Adult InseminatedFemale Spermatheca    54.8 Adult Ovary    152 Adult Testis    63.1 Adult Male Accessory Gland    79.8 Adult Carcass    69.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    128.775 Larval Midgut    46.4 Larval Hindgut    54.5 Larval Malpighian Tubules    78.1 Larval Fat Body    76.1 Larval Salivary Gland    81.1 Larval Trachea    98.55 Larval Carcass    59.3 Adult Head    68.1 Adult Eye    107.225 Adult Brain    84.7 Adult Thoracic-Abdominal Ganglion    84.1 Adult Crop    78.2 Adult Midgut    38.6 Adult Hindgut    61.8 Adult Malpighian Tubules    28.7 Adult Fat Body    54.7 Adult Salivary Gland    96.4 Adult Heart    73.85 Adult VirginFemale Spermatheca    63.5 Adult InseminatedFemale Spermatheca    54.8 Adult Ovary    152 Adult Testis    63.1 Adult Male Accessory Gland    79.8 Adult Carcass    69.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    128.775 Larval Midgut    46.4 Larval Hindgut    54.5 Larval Malpighian Tubules    78.1 Larval Fat Body    76.1 Larval Salivary Gland    81.1 Larval Trachea    98.55 Larval Carcass    59.3 Adult Head    68.1 Adult Eye    107.225 Adult Brain    84.7 Adult Thoracic-Abdominal Ganglion    84.1 Adult Crop    78.2 Adult Midgut    38.6 Adult Hindgut    61.8 Adult Malpighian Tubules    28.7 Adult Fat Body    54.7 Adult Salivary Gland    96.4 Adult Heart    73.85 Adult VirginFemale Spermatheca    63.5 Adult InseminatedFemale Spermatheca    54.8 Adult Ovary    152 Adult Testis    63.1 Adult Male Accessory Gland    79.8 Adult Carcass    69.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    68.1   NA  Eye    107.225   NA  Brain    84.7   128.775  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    84.1   NA  Crop    78.2   46.4  Midgut    38.6   54.5  Hindgut    61.8   78.1  Malpighian Tubules    28.7   76.1  Fat Body    54.7   81.1  Salivary Gland    96.4   NA  Heart    73.85   98.55  Trachea    NA   NA  VirginFemale Spermatheca    63.5   NA  InseminatedFemale Spermatheca    54.8   NA  Ovary    152   NA  Testis    63.1   NA  Male Accessory Gland    79.8   59.3  Carcass    69.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    9 head, mated 20-day male    9 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    10 digestive system, 4-day adult    6 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    17 fat body, pupae P8    8 carcass, larvae L3 wandering    21 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    34 ovary, mated 4-day female    30 testis, mated 4-day male    39 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  26 central nervous system, larvae L3  (33) central nervous system, pupae P8    11 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    9 head, mated 20-day male    9 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae  (30) digestive system, larvae L3 wandering  (32) digestive system, 1-day adult    10 digestive system, 4-day adult    6 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    17 fat body, pupae P8    8 carcass, larvae L3 wandering    21 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female  (34) ovary, mated 4-day female  (30) testis, mated 4-day male  (39) accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    9 head, mated 20-day male    9 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    10 digestive system, 4-day adult    6 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    17 fat body, pupae P8    8 carcass, larvae L3 wandering    21 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    34 ovary, mated 4-day female    30 testis, mated 4-day male    39 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    9 head, mated 20-day male    9 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    10 digestive system, 4-day adult    6 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    17 fat body, pupae P8    8 carcass, larvae L3 wandering    21 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    34 ovary, mated 4-day female    30 testis, mated 4-day male    39 accessory gland, mated 4-day male    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    9 head, mated 20-day male    9 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    10 digestive system, 4-day adult    6 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    17 fat body, pupae P8    8 carcass, larvae L3 wandering    21 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    34 ovary, mated 4-day female    30 testis, mated 4-day male    39 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  26 central nervous system, larvae L3  (33) central nervous system, pupae P8    11 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    9 head, mated 20-day male    9 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae  30 digestive system, larvae L3 wandering  32 digestive system, 1-day adult    10 digestive system, 4-day adult    6 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    17 fat body, pupae P8    8 carcass, larvae L3 wandering    21 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female  (34) ovary, mated 4-day female  30 testis, mated 4-day male  (39) accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    9 head, mated 20-day male    9 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    10 digestive system, 4-day adult    6 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    17 fat body, pupae P8    8 carcass, larvae L3 wandering    21 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    34 ovary, mated 4-day female    30 testis, mated 4-day male    39 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    6 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    9 head, mated 20-day male    9 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    10 digestive system, 4-day adult    6 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    17 fat body, pupae P8    8 carcass, larvae L3 wandering    21 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    34 ovary, mated 4-day female    30 testis, mated 4-day male    39 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    41 embryo 04-06hr    37 embryo 06-08hr    35 embryo 08-10hr    40 embryo 10-12hr    42 embryo 12-14hr    26 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    7 embryo 22-24hr    10 larva L1    7 larva L2    8 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    21 white prepupae new    22 white prepupae 12hr    25 white prepupae 24hr    25 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    6 adult male 01day    12 adult male 05day    13 adult male 30day    9 adult female 01day    6 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr  (41) embryo 04-06hr  (37) embryo 06-08hr  (35) embryo 08-10hr  (40) embryo 10-12hr  (42) embryo 12-14hr  26 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    7 embryo 22-24hr    10 larva L1    7 larva L2    8 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    21 white prepupae new    22 white prepupae 12hr    25 white prepupae 24hr    25 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    6 adult male 01day    12 adult male 05day    13 adult male 30day    9 adult female 01day    6 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    41 embryo 04-06hr    37 embryo 06-08hr    35 embryo 08-10hr    40 embryo 10-12hr    42 embryo 12-14hr    26 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    7 embryo 22-24hr    10 larva L1    7 larva L2    8 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    21 white prepupae new    22 white prepupae 12hr    25 white prepupae 24hr    25 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    6 adult male 01day    12 adult male 05day    13 adult male 30day    9 adult female 01day    6 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    41 embryo 04-06hr    37 embryo 06-08hr    35 embryo 08-10hr    40 embryo 10-12hr    42 embryo 12-14hr    26 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    7 embryo 22-24hr    10 larva L1    7 larva L2    8 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    21 white prepupae new    22 white prepupae 12hr    25 white prepupae 24hr    25 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    6 adult male 01day    12 adult male 05day    13 adult male 30day    9 adult female 01day    6 adult female 05day    15 adult female 30day    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    41 embryo 04-06hr    37 embryo 06-08hr    35 embryo 08-10hr    40 embryo 10-12hr    42 embryo 12-14hr    26 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    7 embryo 22-24hr    10 larva L1    7 larva L2    8 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    21 white prepupae new    22 white prepupae 12hr    25 white prepupae 24hr    25 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    6 adult male 01day    12 adult male 05day    13 adult male 30day    9 adult female 01day    6 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr  (41) embryo 04-06hr  (37) embryo 06-08hr  (35) embryo 08-10hr  (40) embryo 10-12hr  (42) embryo 12-14hr  26 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    7 embryo 22-24hr    10 larva L1    7 larva L2    8 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    21 white prepupae new    22 white prepupae 12hr    25 white prepupae 24hr    25 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    6 adult male 01day    12 adult male 05day    13 adult male 30day    9 adult female 01day    6 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    41 embryo 04-06hr    37 embryo 06-08hr    35 embryo 08-10hr    40 embryo 10-12hr    42 embryo 12-14hr    26 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    7 embryo 22-24hr    10 larva L1    7 larva L2    8 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    21 white prepupae new    22 white prepupae 12hr    25 white prepupae 24hr    25 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    6 adult male 01day    12 adult male 05day    13 adult male 30day    9 adult female 01day    6 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    41 embryo 04-06hr    37 embryo 06-08hr    35 embryo 08-10hr    40 embryo 10-12hr    42 embryo 12-14hr    26 embryo 14-16hr    10 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    7 embryo 22-24hr    10 larva L1    7 larva L2    8 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    21 white prepupae new    22 white prepupae 12hr    25 white prepupae 24hr    25 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    6 adult male 01day    12 adult male 05day    13 adult male 30day    9 adult female 01day    6 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    23 embryonic 1182-4H    15 embryonic GM2    13 embryonic Kc167    26 embryonic S1    24 embryonic S3    15 leg disc CME L1    20 wing disc CME-W2    16 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    39 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    24 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    16 ovary fGS/OSS    22 ovary OSC    45 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (48) Schneider line 2 Sg4    23 embryonic 1182-4H    15 embryonic GM2    13 embryonic Kc167  26 embryonic S1    24 embryonic S3    15 leg disc CME L1    20 wing disc CME-W2    16 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21  (39) wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    24 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1  (28) CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    16 ovary fGS/OSS    22 ovary OSC  (45) ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    23 embryonic 1182-4H    15 embryonic GM2    13 embryonic Kc167    26 embryonic S1    24 embryonic S3    15 leg disc CME L1    20 wing disc CME-W2    16 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    39 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    24 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    16 ovary fGS/OSS    22 ovary OSC    45 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    23 embryonic 1182-4H    15 embryonic GM2    13 embryonic Kc167    26 embryonic S1    24 embryonic S3    15 leg disc CME L1    20 wing disc CME-W2    16 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    39 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    24 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    16 ovary fGS/OSS    22 ovary OSC    45 ovary OSS    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    23 embryonic 1182-4H    15 embryonic GM2    13 embryonic Kc167    26 embryonic S1    24 embryonic S3    15 leg disc CME L1    20 wing disc CME-W2    16 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    39 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    24 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    16 ovary fGS/OSS    22 ovary OSC    45 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (48) Schneider line 2 Sg4    23 embryonic 1182-4H    15 embryonic GM2    13 embryonic Kc167  26 embryonic S1    24 embryonic S3    15 leg disc CME L1    20 wing disc CME-W2    16 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21  (39) wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    24 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1  28 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    16 ovary fGS/OSS    22 ovary OSC  (45) ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    23 embryonic 1182-4H    15 embryonic GM2    13 embryonic Kc167    26 embryonic S1    24 embryonic S3    15 leg disc CME L1    20 wing disc CME-W2    16 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    39 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    24 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    16 ovary fGS/OSS    22 ovary OSC    45 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    23 embryonic 1182-4H    15 embryonic GM2    13 embryonic Kc167    26 embryonic S1    24 embryonic S3    15 leg disc CME L1    20 wing disc CME-W2    16 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    39 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    24 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    13 tumorous blood cells mbn2    16 ovary fGS/OSS    22 ovary OSC    45 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    18 Cadmium 50 mM 12 hrs, larvae L3    17 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    15 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    18 Cadmium 50 mM 12 hrs, larvae L3    17 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    15 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    18 Cadmium 50 mM 12 hrs, larvae L3    17 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    15 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    18 Cadmium 50 mM 12 hrs, larvae L3    17 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    15 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    18 Cadmium 50 mM 12 hrs, larvae L3    17 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    15 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    18 Cadmium 50 mM 12 hrs, larvae L3    17 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    15 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    18 Cadmium 50 mM 12 hrs, larvae L3    17 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    15 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    18 Cadmium 50 mM 12 hrs, larvae L3    17 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    15 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_30 mE1_20_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039732
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG15525 Class Mutagen Stocks Known lesion CG15525G4819 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG15525 Class Mutagen Stocks Known lesion CG15525GD16394 in vitro construct - RNAi in vitro construct - regulatory fusion 3 Yes CG15525GD9046 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG15525KK109307 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CG15525NIG.15525R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6213 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9046} NA P{GD16394} NA P{KK109307} NA P{NIG.15525R} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG15525G4819 NA P{GSV1}C495C495 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG15525 - CG17187 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG15525 - CG6015 experimental knowledge based (Guruharsha et al., 2011) CG15525 - CG6197 experimental knowledge based (Guruharsha et al., 2011) CG15525 - CG6674 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG15525 - CG9667 experimental knowledge based (Guruharsha et al., 2011) CG15525 - CycB3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG15525 - crn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG15525 - l(1)10Bb experimental knowledge based (Guruharsha et al., 2011) CG15525 - sip1 experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG15525 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68412 DroID - A comprehensive database of gene and protein interactions. • FBgn0039732 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43556
Orthologs
OrthoDB Orthologs (37) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6R24FD Dipteran inclusive ortholog search EOG6GHZZG Insect inclusive ortholog search EOG68CZS3 Arthropod inclusive ortholog search EOG6573Q6 Metazoa inclusive ortholog search EOG6WT85W
Orthologs in Drosophila Species (EOG6R24FD)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG15525     Drosophila simulans   Dsim\GD17487 Y   Drosophila sechellia   Dsec\GM12197 Y   Drosophila erecta   Dere\GG11979 Y   Drosophila yakuba   Dyak\GE10404 Y   Drosophila ananassae   Dana\GF16213 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA13783 Y   Drosophila persimilis   Dper\GL13490 Y   Drosophila willistoni   Dwil\GK14082 Y   Drosophila virilis   Dvir\GJ14326 Y   Drosophila mojavensis   Dmoj\GI21967 Y   Drosophila grimshawi   Dgri\GH22169 Y
Orthologs in non-Drosophila Dipterans (EOG6GHZZG)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009922   Anopheles gambiae Malaria mosquito  Agam\AGAP004668   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ001031
Orthologs in non-Dipteran Insects (EOG68CZS3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC551200   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005021   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH13127   Atta cephalotes Leafcutter ant  Acep\ACEP12303   Camponotus floridanus Florida carpenter ant  Cflo\CFLO18599   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20632   Linepithema humile Argentine ant  Lhum\LH13492   Pogonomyrmex barbatus Red harvester ant  Pbar\PB13780   Solenopsis invicta Red fire ant  Sinv\SINV17160   Acyrthosiphon pisum Pea aphid  Apim\ACYPI007804   Pediculus humanus Human body louse  Phum\PHUM040980   Tribolium castaneum Red flour beetle  Tcas\TC004360
Orthologs in non-Insect Arthropods (EOG6573Q6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_308635   Ixodes scapularis Deer tick  Isca\ISCW007912
Orthologs in non-Arthropod Metazoa (EOG6WT85W)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\Y69A2AR.21   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007656gn   Danio rerio Zebrafish  Drer\ccdc12   Xenopus tropicalis Western clawed frog  Xtro\ccdc12   Gallus gallus Domestic chicken  Ggal\CCDC12   Mus musculus House mouse  Mmus\Ccdc12   Rattus norvegicus Norway rat  Rnor\Ccdc12   Homo sapiens Human  Hsap\ENSG00000160799
Human Orthologs (1)
Gene OMIM HGNC Hsap\ENSG00000160799
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD17487 Drosophila sechellia Dsec\GM12197 Drosophila erecta Dere\GG11979 Drosophila yakuba Dyak\GE10404 Drosophila ananassae Dana\GF16213 Drosophila pseudoobscura pseudoobscura Dpse\GA13783 Drosophila persimilis Dper\GL13490 Drosophila willistoni Dwil\GK14082 Drosophila virilis Dvir\GJ14326 Drosophila mojavensis Dmoj\GI21967 Drosophila grimshawi Dgri\GH22169
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	31790 w1118; P{EP}CG15525G4819 CG7911G4819
VDRC	v39993 w1118; P{GD9046}v39993 v48658 w1118; P{GD16394}v48658 v48660 w1118; P{GD16394}v48660 v52458 w1118; P{GD16394}v52458
Genomic Clones ( 1 )
	BACR07A18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 10 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD23244
Other clones	DPiM_SD23244 MIP04834
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	77234 214411.24 556934 Dmel_dig_006399_0607_0684 EN11722 EP12059 FGC019B03
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039732 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43556
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG15525 BcDNA:SD23244 (FlyBase, 1996-)
Additional comments	One or more of the processed transcripts for this gene contain(s) two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by CG7911 (CG7911) and CG15525 (CG15525). (FlyBase Genome Annotators, 2007) Source for merge of CG15525 BcDNA:SD23244 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143500 RefSeq (Proteins) • NP_651757 DDBJ / EMBL / GenBank • AAF56984 AAM51122 AY119262 BI640401 Entrez Gene - A searchable database of RefSeq genes. • 43556 UniProtKB/TrEMBL • Q8MRU7 Q9VAC7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • mRNA splicing factor, Cwf18 (IPR013169)
Linkouts
	BioGRID - A database of protein and genetic interactions • 68412 DroID - A comprehensive database of gene and protein interactions. • FBgn0039732 DRSC - Results from RNAi screens. • FBgn0039732 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039732 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039732 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43556 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43556 modMine - Data generated by the modENCODE project. • FBgn0039732
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	BcDNA:SD23244   CG15525 (FlyBase Genome Annotators, 2007, Molnar et al., 2006, Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
	FBgn0062853
References ( 16 )
Research paper	Molnar et al., 2006, Genetics 174(3): 1635--1659 A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. [FBrf0195387]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Bellen, 2010.7.14, BDGP_2010_0715.GenExel.xml BDGP_2010_0715.GenExel.xml [FBrf0211255] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Genome Annotators, 2007, Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. [FBrf0199252] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Curated genome annotation	FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705]