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Gene Dmel\Jon99Fii

General Information
Symbol	Dmel\Jon99Fii	Species	D. melanogaster
Name	Jonah 99Fii	Annotation symbol	CG2229
Feature type	protein_coding_gene	FlyBase ID	FBgn0039777
Gene Model Status	Current	Stock availability	1 publicly available
Also Known As	Jon99F
Genomic Location
Chromosome (arm)	3R	Recombination map	3-[101]
Cytogenetic map	99F6-99F6	Sequence location	3R:26,312,735..26,313,648 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Jonah 99Fii is referred to in FlyBase by the symbol Dmel\Jon99Fii (CG2229, FBgn0039777). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: endopeptidase activity. It is reported to be involved in the biological process: proteolysis. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1/S6, chymotrypsin/Hap, active site; Peptidase S1A, chymotrypsin-type; Peptidase cysteine/serine, trypsin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected. Peak expression observed during early larval stages. Summary of FlyAtlas Anatomical Expression Data: No FlyAtlas data available because no Affy2 ProbeSet aligns to an exon of Jon99Fii. Comments on Affy2 ProbeSet: No relevant information because no Affy2 ProbeSet aligns to an exon of Jon99Fii. Gene sequence location is 3R:26312735..26313648.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	Clones TA01126
FB2012_01	Sequence features BKN42680 HFA15430
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 99F6-99F6   Limits computationally determined from genome sequence between P{PZ}ncd05884 and P{lacW}l(3)s2500s2500
Experimentally Determined Cytological Location
Cytogenetic map Notes References 99F-99F   (determined by in situ hybridisation)   (Carlson and Hogness, 1985)
Experimentally Determined Recombination Data
Location	3-[101] (Lindsley and Zimm, 1992)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Jon99Fii for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Perfect match to CG18030 on opposite strand.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Jon99Fii-RA FBtr0085690  NM_143542   914   267
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Jon99Fii-PA   FBpp0085052   28.9   267   7.04     NP_651799   AAF57055
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Peptidase S1/S6, chymotrypsin/Hap, active site (IPR018114) Peptidase S1/S6, chymotrypsin/Hap (IPR001254) Peptidase S1A, chymotrypsin-type (IPR001314) Peptidase cysteine/serine, trypsin-like (IPR009003)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF57055   AI107311   AI257502   AI257762   AI258083   AI258158   AI258262   AI258719   AI258779   AI259622   AI259649   AI260693   AI260745   AI260784   AI260869   AI260980   AI293387   AI293574   AI293807   AI293848   AI294302   AI294690   AI294713   AI295734   AI296061   AI296334   AI296352   AI296435   AI296717   AI296749   AI296763   AI296844   AI297820   AY070585 AAL48056   AY071483   AY231992   BI167427   BI227720   BI234247   BI355991   BI365262   BI366258   BI371575   BI485445   BI579358   BQ103131   BT021364   BT128767   CK131846   CK132089   CK132415   CK132515   CK657252   CK657456   CK657463   CK658157   CK658223   CK658251   CK658755   CK658949   CK659186   CK659478   CK659517   CK659749   CK659754   CK660207   CK660285   CK660302   CK660316   CK661536   CK661698   CK661726   CK661741   CK661847   CK661965   CK662087   CK662178   CK662256   CO182729   CO185277   CO192756   CO294034   EC212751   EL875853   EL885317   EL886858   EL887049   EV588900   EV591027   EV594522
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VA67
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039777    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039777 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected. Peak expression observed during early larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039777 expression level Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    31 embryo 08-10hr    3 embryo 10-12hr    15 embryo 12-14hr    7 embryo 14-16hr    14 embryo 16-18hr    24 embryo 18-20hr    763 embryo 20-22hr    31606 embryo 22-24hr    20862 larva L1    76324 larva L2    107504 larva L3 12hr old    73071 larva L3 puffstage 1-2    80915 larva L3 puffstage 3-6    62327 larva L3 puffstage 7-9    21161 white prepupae new    2619 white prepupae 12hr    93 white prepupae 24hr    50 pupae 2d postWPP    28 pupae 3d postWPP    0 pupae 4d postWPP    16 adult male 01day    11145 adult male 05day    26963 adult male 30day    7367 adult female 01day    16238 adult female 05day    17875 adult female 30day    21891 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    31 embryo 08-10hr    3 embryo 10-12hr    15 embryo 12-14hr    7 embryo 14-16hr    14 embryo 16-18hr    24 embryo 18-20hr  (763) embryo 20-22hr  (31606) embryo 22-24hr  (20862) larva L1  (76324) larva L2  (107504) larva L3 12hr old  (73071) larva L3 puffstage 1-2  (80915) larva L3 puffstage 3-6  (62327) larva L3 puffstage 7-9  (21161) white prepupae new  (2619) white prepupae 12hr    93 white prepupae 24hr    50 pupae 2d postWPP    28 pupae 3d postWPP    0 pupae 4d postWPP    16 adult male 01day  (11145) adult male 05day  (26963) adult male 30day  (7367) adult female 01day  (16238) adult female 05day  (17875) adult female 30day  (21891) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    31 embryo 08-10hr    3 embryo 10-12hr    15 embryo 12-14hr    7 embryo 14-16hr    14 embryo 16-18hr    24 embryo 18-20hr    763 embryo 20-22hr  (31606) embryo 22-24hr  (20862) larva L1  (76324) larva L2  (107504) larva L3 12hr old  (73071) larva L3 puffstage 1-2  (80915) larva L3 puffstage 3-6  (62327) larva L3 puffstage 7-9  (21161) white prepupae new  (2619) white prepupae 12hr    93 white prepupae 24hr    50 pupae 2d postWPP    28 pupae 3d postWPP    0 pupae 4d postWPP    16 adult male 01day  (11145) adult male 05day  (26963) adult male 30day  (7367) adult female 01day  (16238) adult female 05day  (17875) adult female 30day  (21891) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    31 embryo 08-10hr    3 embryo 10-12hr    15 embryo 12-14hr    7 embryo 14-16hr    14 embryo 16-18hr    24 embryo 18-20hr    763 embryo 20-22hr  (31606) embryo 22-24hr  (20862) larva L1  (76324) larva L2  (107504) larva L3 12hr old  (73071) larva L3 puffstage 1-2  (80915) larva L3 puffstage 3-6  (62327) larva L3 puffstage 7-9  (21161) white prepupae new    2619 white prepupae 12hr    93 white prepupae 24hr    50 pupae 2d postWPP    28 pupae 3d postWPP    0 pupae 4d postWPP    16 adult male 01day  (11145) adult male 05day  (26963) adult male 30day    7367 adult female 01day  (16238) adult female 05day  (17875) adult female 30day  (21891) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    31 embryo 08-10hr    3 embryo 10-12hr    15 embryo 12-14hr    7 embryo 14-16hr    14 embryo 16-18hr    24 embryo 18-20hr    763 embryo 20-22hr    31606 embryo 22-24hr    20862 larva L1    76324 larva L2    107504 larva L3 12hr old    73071 larva L3 puffstage 1-2    80915 larva L3 puffstage 3-6    62327 larva L3 puffstage 7-9    21161 white prepupae new    2619 white prepupae 12hr    93 white prepupae 24hr    50 pupae 2d postWPP    28 pupae 3d postWPP    0 pupae 4d postWPP    16 adult male 01day    11145 adult male 05day    26963 adult male 30day    7367 adult female 01day    16238 adult female 05day    17875 adult female 30day    21891 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039777 expression level Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    31 embryo 08-10hr    3 embryo 10-12hr    15 embryo 12-14hr    7 embryo 14-16hr    14 embryo 16-18hr    24 embryo 18-20hr    763 embryo 20-22hr    31606 embryo 22-24hr    20862 larva L1    76324 larva L2    107504 larva L3 12hr old    73071 larva L3 puffstage 1-2    80915 larva L3 puffstage 3-6    62327 larva L3 puffstage 7-9    21161 white prepupae new    2619 white prepupae 12hr    93 white prepupae 24hr    50 pupae 2d postWPP    28 pupae 3d postWPP    0 pupae 4d postWPP    16 adult male 01day    11145 adult male 05day    26963 adult male 30day    7367 adult female 01day    16238 adult female 05day    17875 adult female 30day    21891 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    31 embryo 08-10hr    3 embryo 10-12hr    15 embryo 12-14hr    7 embryo 14-16hr    14 embryo 16-18hr    24 embryo 18-20hr  (763) embryo 20-22hr  (31606) embryo 22-24hr  (20862) larva L1  (76324) larva L2  (107504) larva L3 12hr old  (73071) larva L3 puffstage 1-2  (80915) larva L3 puffstage 3-6  (62327) larva L3 puffstage 7-9  (21161) white prepupae new  (2619) white prepupae 12hr    93 white prepupae 24hr    50 pupae 2d postWPP    28 pupae 3d postWPP    0 pupae 4d postWPP    16 adult male 01day  (11145) adult male 05day  (26963) adult male 30day  (7367) adult female 01day  (16238) adult female 05day  (17875) adult female 30day  (21891) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    31 embryo 08-10hr    3 embryo 10-12hr    15 embryo 12-14hr    7 embryo 14-16hr    14 embryo 16-18hr    24 embryo 18-20hr    763 embryo 20-22hr  (31606) embryo 22-24hr  (20862) larva L1  (76324) larva L2  (107504) larva L3 12hr old  (73071) larva L3 puffstage 1-2  (80915) larva L3 puffstage 3-6  (62327) larva L3 puffstage 7-9  (21161) white prepupae new  (2619) white prepupae 12hr    93 white prepupae 24hr    50 pupae 2d postWPP    28 pupae 3d postWPP    0 pupae 4d postWPP    16 adult male 01day  (11145) adult male 05day  (26963) adult male 30day  (7367) adult female 01day  (16238) adult female 05day  (17875) adult female 30day  (21891) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    31 embryo 08-10hr    3 embryo 10-12hr    15 embryo 12-14hr    7 embryo 14-16hr    14 embryo 16-18hr    24 embryo 18-20hr    763 embryo 20-22hr  (31606) embryo 22-24hr  (20862) larva L1  (76324) larva L2  (107504) larva L3 12hr old  (73071) larva L3 puffstage 1-2  (80915) larva L3 puffstage 3-6  (62327) larva L3 puffstage 7-9  (21161) white prepupae new    2619 white prepupae 12hr    93 white prepupae 24hr    50 pupae 2d postWPP    28 pupae 3d postWPP    0 pupae 4d postWPP    16 adult male 01day  11145 adult male 05day  (26963) adult male 30day    7367 adult female 01day  16238 adult female 05day  17875 adult female 30day  (21891) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    46 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    31 embryo 08-10hr    3 embryo 10-12hr    15 embryo 12-14hr    7 embryo 14-16hr    14 embryo 16-18hr    24 embryo 18-20hr    763 embryo 20-22hr    31606 embryo 22-24hr    20862 larva L1    76324 larva L2    107504 larva L3 12hr old    73071 larva L3 puffstage 1-2    80915 larva L3 puffstage 3-6    62327 larva L3 puffstage 7-9    21161 white prepupae new    2619 white prepupae 12hr    93 white prepupae 24hr    50 pupae 2d postWPP    28 pupae 3d postWPP    0 pupae 4d postWPP    16 adult male 01day    11145 adult male 05day    26963 adult male 30day    7367 adult female 01day    16238 adult female 05day    17875 adult female 30day    21891 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_16
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039777
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 Jon99FiiGD6349 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Jon99Fii Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Jon99Fii Class Mutagen Stocks Known lesion Jon99FiiGD6349 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6215 (Ryder, 2004.4.26) Df(3R)Exel6216 (Ryder, 2004.4.26, Abrams et al., 2006)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6349} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
endopeptidase activity non-traceable author statement (Ross et al., 2003) serine-type endopeptidase activity inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
proteolysis inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 (FlyBase Curators et al., 2004-) non-traceable author statement (Ross et al., 2003)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Jon99Fii allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68474 DroID - A comprehensive database of gene and protein interactions. • FBgn0039777 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43621
Orthologs
Genome-wide drosophilid orthologs	Dere\GG11754
Curated drosophilid orthologs	Dyak\GE10882
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0068353 FBgn0192948 FBgn0167815 FBgn0039778
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
VDRC	v30973 w1118; P{GD6349}v30973
Genomic Clones ( 1 )
	BACR48G16 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 88 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LP12217 RE55321 RE68767
Other clones	TA01126 yak-ad_CG2229
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH04110 LP01177 LP01284 LP01411 LP01978 LP02057 LP03080 LP03116 LP04649 LP04711 LP04757 LP04860 LP04954 LP05037 LP05893 LP06226 LP06744 LP07033 LP07089 LP07640 LP08119 LP08147 LP09447 LP09864 LP10196 LP10219 LP10325 LP10739 LP10816 LP10834 LP10940 LP12221 LP12872 LP13341 LP13932 LP14082 LP14783 LP14989 LP15049 LP15975 LP16292 LP16773 LP17268 LP17331 LP17719 LP17731 LP18563 LP18729 LP18755 LP18781 LP21122 LP21354 LP21393 LP21419 LP21595 LP21821 LP22048 LP22193 LP22329 LP23392 LP23768 LP23780 RE07814 RE24937 RE29921 RE37067 RE50514 RE51757 RE58493 RE73378
Other clones	76236 Dmel_neb_011595_0146_1197 Dmel_neb_013164_0397_3206 Dmel_neb_014136_0606_2790 EC23823 EC30123 EC34423 EK205541 IP05771 IP16514 IP18061 IP18261 UUGC0529
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039777 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43621
Antibody Information
Other Information
Discoverer
Etymology
	One of a number of genes isolated from a cDNA library made from third instar salivary glands, but subsequently found not to be expressed in the salivary glands but instead expressed specifically and abundantly in the midgut (which resulted in contamination of the original cDNA library). This surprising discovery prompted the name "Jonah" for this family of genes, after the Biblical prophet who unexpectedly turned up in the gut. (Carlson and Hogness, 1985)
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Jon99Fii CG2229 (Schaeffer, 2004.1.1)
Additional comments	Characterization of LAP genes "Lap-A" and "Lap-D" from the distribution and enzymatic activity of their proteins reveals a striking resemblance to the description of Jonah genes in 99C ("Jon99Co", "Jon99Ci", "Jon99Cii" and "Jon99Ciii") and 99F ("Jon99Fi" and "Jon99Fii") and the pattern of expression of their transcripts. At least one of the Jonah genes in 99C or 99F may correspond to "Lap-A" or "Lap-D". (Collett and Seymour-Jones, 1992)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143542 RefSeq (Proteins) • NP_651799 DDBJ / EMBL / GenBank • AAF57055 AAL48056 AY070585 BI485445 Entrez Gene - A searchable database of RefSeq genes. • 43621 UniProtKB/TrEMBL • Q9VA67
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Peptidase S1/S6, chymotrypsin/Hap, active site (IPR018114) Peptidase S1/S6, chymotrypsin/Hap (IPR001254) Peptidase S1A, chymotrypsin-type (IPR001314) Peptidase cysteine/serine, trypsin-like (IPR009003)
Linkouts
	BioGRID - A database of protein and genetic interactions • 68474 DroID - A comprehensive database of gene and protein interactions. • FBgn0039777 DRSC - Results from RNAi screens. • FBgn0039777 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039777 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039777 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43621 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43621 modMine - Data generated by the modENCODE project. • FBgn0039777 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0068353 FBgn0192948 FBgn0167815 FBgn0039778
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	CG2229 (Blanchette et al., 2004, Abrams and Andrew, 2002, Roxstrom-Lindquist et al., 2004) Jon99F (Collett and Seymour-Jones, 1992, Lindsley and Zimm, 1992, ) Jon99Fii (Abrams et al., 2006, Junell et al., 2007) SP135 (Ross et al., 2003)
Name Synonym	Jonah 99F (Schaeffer, 2004.1.1) Jonah 99Fii
Secondary FlyBase IDs
	FBgn0001289
References ( 20 )
Research paper	Junell et al., 2007, Insect Biochem. Molec. Biol. 37(3): 202--212 Isolation of regulators of Drosophila immune defense genes by a double interaction screen in yeast. [FBrf0194397] Abrams et al., 2006, Development 133(18): 3517--3527 Fork head and Sage maintain a uniform and patent salivary gland lumen through regulation of two downstream target genes, PH4αSG1 and PH4αSG2. [FBrf0195124] Blanchette et al., 2004, Molec. Cell 14(6): 775--786 Genome-wide analysis reveals an unexpected function for the Drosophila splicing factor U2AF50 in the nuclear export of intronless mRNAs. [FBrf0179139] Roxstrom-Lindquist et al., 2004, EMBO Rpts 5(2): 207--212 Parasite-specific immune response in adult Drosophila melanogaster: a genomic study. [FBrf0167559] Ross et al., 2003, Gene 304(1-2): 117--131 Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. [FBrf0155784] Abrams and Andrew, 2002, Mech. Dev. 112(1-2): 165--171 Prolyl 4-hydroxylase alpha-related proteins in Drosophila melanogaster: tissue-specific embryonic expression of the 99F8-9 cluster. [FBrf0144992] Collett and Seymour-Jones, 1992, D. I. S. 71: 197 Leucine aminopeptidase (LAP) is coded for by Jonah family genes in the chromosomal region of 99 in Drosophila melanogaster. [FBrf0055717] Carlson and Hogness, 1985, Dev. Biol. 108: 341--354 The Jonah genes: a new multigene family in Drosophila melanogaster. [FBrf0042367]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579]
Personal communication to FlyBase	FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Schaeffer, 2004.1.1, Jonah99. Jonah99. [FBrf0178758]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Gong, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126669]