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Gene Dmel\CG1746

General Information
Symbol	Dmel\CG1746	Species	D. melanogaster
Name		Annotation symbol	CG1746
Feature type	protein_coding_gene	FlyBase ID	FBgn0039830
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	100B7-100B7	Sequence location	3R:27,041,867..27,045,352 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG1746 (FBgn0039830). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: hydrogen-exporting ATPase activity, phosphorylative mechanism. Based on sequence similarity, it is predicted to be involved in the biological process: proton transport. 7 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: ATPase, F0 complex, subunit C; ATPase, F0 complex, subunit C, DCCD-binding site; V-ATPase proteolipid subunit C-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed during early larval stages, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1629342_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of CG1746. Gene sequence location is 3R:27041867..27045352.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 100B7-100B7   Limits computationally determined from genome sequence between P{PZ}Aph-407028&P{PZ}dcorK215 and P{PZ}l(3)rM731rM731
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG1746 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47 Low-frequency RNA-Seq exon junction(s) not annotated. Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG1746-RA FBtr0085772  NM_143595   1439   138 CG1746-RB FBtr0085774  NM_170543   1347   138 CG1746-RC FBtr0085773  NM_170544   1794   138 CG1746-RE FBtr0305121  NM_001260453   1730   138 CG1746-RF FBtr0305122  NM_001260454   1350   134 CG1746-RG FBtr0306237  NM_001260455   722   138
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG1746-PA   FBpp0085134   14.4   138   10.76     NP_651852   AAN14267 CG1746-PB   FBpp0085136   14.4   138   10.76     NP_733422   AAF57131 CG1746-PC   FBpp0085135   14.4   138   10.76     NP_733423   AAN14268 CG1746-PE   FBpp0293652   14.4   138   10.76     NP_001247382   AFH06699 CG1746-PF   FBpp0293653   14.1   134   10.11     NP_001247383   AFH06700 CG1746-PG   FBpp0297347   14.4   138   10.76     NP_001247384   AFH06701
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • ATPase, F0 complex, subunit C (IPR000454) V-ATPase proteolipid subunit C-like domain (IPR002379) ATPase, F0 complex, subunit C, DCCD-binding site (IPR020537) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME01746
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201886   AA202792   AA391181   AA567056   AA567085   AA567118   AA567457   AA695026   AA695252   AA695474   AA696317   AA696721   AA696920   AA698348   AA735704   AA735942   AA801752   AA802224   AA802278   AA803036   AA803445   AA803844   AA803887   AA951260   AA951284   AA952081   AE014297 AAF57131   AE014297 AAN14267   AE014297 AAN14268   AF171841   AE014297 AFH06699   AE014297 AFH06700   AE014297 AFH06701   AI062497   AI063677   AI063694   AI063803   AI063997   AI064359   AI107342   AI108009   AI108224   AI108249   AI108516   AI108808   AI109605   AI110128   AI113507   AI135495   AI135868   AI238236   AI258169   AI259102   AI259471   AI259666   AI260085   AI260414   AI295230   AI296022   AI296116   AI387630   AI402449   AI403156   AI403386   AI404727   AI404830   AI405208   AI513225   AI517659   AI517698   AI517730   AY231917   AY441220   AY826163   BE976541   BE978619   BF489069   BF498558   BG632184   BG637016   BG640727   BI161909   BI162956   BI164404   BI165549   BI165709   BI165955   BI166358   BI166948   BI167663   BI167668   BI168891   BI169825   BI170104   BI170140   BI170703   BI171707   BI213164   BI214411   BI216524   BI216914   BI227946   BI228120   BI228133   BI228848   BI229428   BI230176   BI232609   BI232839   BI234607   BI234977   BI235360   BI235465   BI236254   BI236814   BI238025   BI238209   BI238629   BI238964   BI240121   BI240536   BI240709   BI241155   BI241639   BI242011   BI243108   BI243143   BI243410   BI352861   BI353103   BI353517   BI354604   BI357233   BI357618   BI358313   BI362049   BI363760   BI363761   BI364063   BI366056   BI366057   BI366394   BI368441   BI369320   BI370664   BI372248   BI373179   BI374786   BI375715   BI376161   BI485674   BI485714   BI563681   BI563877   BI563921   BI564209   BI564604   BI565627   BI566024   BI567050   BI567068   BI567255   BI567396   BI567471   BI568024   BI568175   BI568284   BI568328   BI569607   BI569783   BI570202   BI570268   BI570575   BI570682   BI570926   BI571542   BI572951   BI572955   BI574424   BI574471   BI574646   BI575203   BI575321   BI576203   BI576497   BI576942   BI576991   BI577049   BI578271   BI581573   BI581582   BI583002   BI583037   BI583710   BI583812   BI584412   BI584596   BI585796   BI586408   BI586768   BI587210   BI587584   BI588202   BI588346   BI588607   BI590237   BI590423   BI590973   BI590998   BI591060   BI591385   BI591520   BI591526   BI591822   BI591823   BI592439   BI592454   BI592496   BI592872   BI592888   BI593099   BI593323   BI593400   BI593475   BI604473   BI604882   BI605095   BI605162   BI605524   BI606312   BI606464   BI606703   BI607087   BI607543   BI607938   BI608048   BI609217   BI609417   BI610478   BI610663   BI610854   BI612081   BI612107   BI612301   BI612302   BI612976   BI613045   BI613324   BI613372   BI613700   BI613768   BI613846   BI613948   BI614180   BI614283   BI614498   BI614763   BI615391   BI615543   BI616268   BI616274   BI616761   BI616907   BI616952   BI617278   BI617357   BI617437   BI617786   BI618206   BI618225   BI618575   BI619021   BI619315   BI619323   BI619714   BI620699   BI620871   BI621414   BI621804   BI621819   BI621953   BI622699   BI622778   BI622785   BI622811   BI623390   BI623605   BI623921   BI623933   BI624365   BI625858   BI626038   BI626979   BI627681   BI627788   BI627792   BI627908   BI628349   BI628360   BI628404   BI628987   BI629677   BI629683   BI629691   BI629805   BI630223   BI630534   BI630590   BI630620   BI630671   BI630792   BI630808   BI630938   BI631163   BI631277   BI631302   BI631695   BI632847   BI634008   BI634273   BI634356   BI634367   BI634451   BI634493   BI634792   BI640751   BP540506   BP540507   BP540509   BP540510   BP540703   BP540704   BP541099   BP541100   BP541453   BP541556   BP541597   BP541610   BP541763   BP541886   BP542038   BP542607   BP542720   BP542943   BP542944   BP543264   BP545113   BP545114   BP545389   BP545390   BP545787   BP545843   BP546077   BP546199   BP546274   BP546612   BP546629   BP546798   BP546806   BP546839   BP546875   BP546881   BP547004   BP547032   BP547078   BP547127   BP547233   BP547383   BP547457   BP547524   BP547618   BP547658   BP547741   BP547770   BP547779   BP547893   BP547942   BP547951   BP548144   BP548150   BP548189   BP548205   BP548221   BP548253   BP548262   BP548315   BP548320   BP548326   BP548492   BP548583   BP549084   BP549185   BP549186   BP549245   BP549572   BP549573   BP550201   BP550527   BP550528   BP550715   BP550716   BP550815   BP550816   BP550856   BP550956   BP551100   BP551101   BP551361   BP551362   BP551438   BP551439   BP551628   BP551928   BP552190   BP552482   BP552483   BP552854   BP552855   BP553439   BP553440   BP553465   BP553466   BP553521   BP553522   BP553744   BP553745   BP554026   BP554230   BP554565   BP554566   BP554666   BP554667   BP555095   BP555227   BP555228   BP555400   BP555401   BP555583   BP555602   BP555603   BP555687   BP555688   BP556586   BP556587   BP556804   BP556805   BP556869   BP556870   BP557204   BP557205   BP558411   BP558412   BP558771   BP558772   BP558803   BP558804   BP558977   BP558978   BP558981   BP558982   BP559001   BP559002   BP559144   BP559195   BP559196   BP559906   BP559907   BT011492   BT058051   BT082092   BT132846   BX005683   BX006155   BX007778   BX009642   BX012752   BX017247   BX020170   BX022703   BX025627   BX025828   BX029299   BX029637   BX030169   BX031060   BX035235   BX035357   BX037233   BX037281   BX039745   BX045101   BX045725   BX049282   BX050386   BX054404   BX058896   BX060912   BX061448   BX062797   BX067312   BX069058   BX071181   BX072016   CK657726   CK658214   CK658934   CO152787   CO154914   CO156883   CO180796   CO181675   CO181935   CO182680   CO183645   CO185218   CO185328   CO193706   CO195890   CO262458   CO272187   CO283516   CO289157   CO291186   CO294328   CO297123   CO305354   CO313822   CO314106   CO325545   CO329422   CO331070   CO331116   CO335757   CO336445   CO336767   CO337323   CO341911   CR937452   DQ440000   DQ910368   EC064577   EC071658   EC081951   EC202752   EC209203   EC212745   EC216210   EC227769   EC228753   EC230679   EC233704   EC235914   EC237357   EC239565   EC245411   EC247755   EC248827   EC261362   EC261440   EC262378   EC263574   EC263820   EC266985   EL871162   EL871163   EL871283   EL871284   EL871405   EL874015   EL874133   EL874367   EL879607   EL881301   EL882701   EL882702   EL882912   ES688922   EV575057   EV575618   EV575983   EV576274   EV576341   EV576369   EV576789   EV576890   EV576917   EV576995   EV577338   EV577829   EV578460   EV578754   EV579308   EV579375   EV579580   EV580026   EV580718   EV580769   EV581113   EV581225   EV581288   EV581306   EV581355   EV581386   EV581573   EV581680   EV582000   EV582020   EV582099   EV582268   EV582704   EV583245   EV583341   EV583448   EV583645   EV584393   EV584399   EV584564   EV584872   EV584910   EV585093   EV585101   EV585174   EV585393   EV588385   EV588926   EV589941   EV589958   EV590463   EV590810   EV592465   EV592764   EV593804   EV593920   EV595047   EV595356   EV595851   EV596393   EV596472   EV596772   EV597683   EV597860   EV597881   EV597886   EV598275   EV598653   EV598955   EV599333   EV599871   EV600733
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q6NN09
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) dorsal pharyngeal muscle primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic anal pad   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) embryonic/larval somatic muscle   (Fisher et al., 2012) embryonic/larval visceral muscle   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2511.3 Larval Midgut    2396.7 Larval Hindgut    3516.6 Larval Malpighian Tubules    2168.4 Larval Fat Body    1378 Larval Salivary Gland    3423 Larval Trachea    2159.425 Larval Carcass    4099.825 Adult Head    3417.5 Adult Eye    4618.875 Adult Brain    3092.8 Adult Thoracic-Abdominal Ganglion    4240.6 Adult Crop    3541.2 Adult Midgut    2549.9 Adult Hindgut    3867.7 Adult Malpighian Tubules    3767.2 Adult Fat Body    4303.6 Adult Salivary Gland    5765.2 Adult Heart    4270.45 Adult VirginFemale Spermatheca    3779.2 Adult InseminatedFemale Spermatheca    3560.3 Adult Ovary    2450.8 Adult Testis    454.3 Adult Male Accessory Gland    1445.1 Adult Carcass    5588.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2511.3) Larval Midgut  (2396.7) Larval Hindgut  (3516.6) Larval Malpighian Tubules  (2168.4) Larval Fat Body  (1378) Larval Salivary Gland  (3423) Larval Trachea  (2159.425) Larval Carcass  (4099.825) Adult Head  (3417.5) Adult Eye  (4618.875) Adult Brain  (3092.8) Adult Thoracic-Abdominal Ganglion  (4240.6) Adult Crop  (3541.2) Adult Midgut  (2549.9) Adult Hindgut  (3867.7) Adult Malpighian Tubules  (3767.2) Adult Fat Body  (4303.6) Adult Salivary Gland  (5765.2) Adult Heart  (4270.45) Adult VirginFemale Spermatheca  (3779.2) Adult InseminatedFemale Spermatheca  (3560.3) Adult Ovary  (2450.8) Adult Testis    454.3 Adult Male Accessory Gland  (1445.1) Adult Carcass  (5588.7) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2511.3) Larval Midgut  (2396.7) Larval Hindgut  (3516.6) Larval Malpighian Tubules  (2168.4) Larval Fat Body  (1378) Larval Salivary Gland  (3423) Larval Trachea  (2159.425) Larval Carcass  (4099.825) Adult Head  (3417.5) Adult Eye  (4618.875) Adult Brain  (3092.8) Adult Thoracic-Abdominal Ganglion  (4240.6) Adult Crop  (3541.2) Adult Midgut  (2549.9) Adult Hindgut  (3867.7) Adult Malpighian Tubules  (3767.2) Adult Fat Body  (4303.6) Adult Salivary Gland  (5765.2) Adult Heart  (4270.45) Adult VirginFemale Spermatheca  (3779.2) Adult InseminatedFemale Spermatheca  (3560.3) Adult Ovary  (2450.8) Adult Testis    454.3 Adult Male Accessory Gland  (1445.1) Adult Carcass  (5588.7) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2511.3 Larval Midgut    2396.7 Larval Hindgut    3516.6 Larval Malpighian Tubules    2168.4 Larval Fat Body    1378 Larval Salivary Gland    3423 Larval Trachea    2159.425 Larval Carcass    4099.825 Adult Head    3417.5 Adult Eye    4618.875 Adult Brain    3092.8 Adult Thoracic-Abdominal Ganglion    4240.6 Adult Crop    3541.2 Adult Midgut    2549.9 Adult Hindgut    3867.7 Adult Malpighian Tubules    3767.2 Adult Fat Body    4303.6 Adult Salivary Gland    5765.2 Adult Heart    4270.45 Adult VirginFemale Spermatheca    3779.2 Adult InseminatedFemale Spermatheca    3560.3 Adult Ovary    2450.8 Adult Testis    454.3 Adult Male Accessory Gland    1445.1 Adult Carcass    5588.7 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2511.3 Larval Midgut    2396.7 Larval Hindgut    3516.6 Larval Malpighian Tubules    2168.4 Larval Fat Body    1378 Larval Salivary Gland    3423 Larval Trachea    2159.425 Larval Carcass    4099.825 Adult Head    3417.5 Adult Eye    4618.875 Adult Brain    3092.8 Adult Thoracic-Abdominal Ganglion    4240.6 Adult Crop    3541.2 Adult Midgut    2549.9 Adult Hindgut    3867.7 Adult Malpighian Tubules    3767.2 Adult Fat Body    4303.6 Adult Salivary Gland    5765.2 Adult Heart    4270.45 Adult VirginFemale Spermatheca    3779.2 Adult InseminatedFemale Spermatheca    3560.3 Adult Ovary    2450.8 Adult Testis    454.3 Adult Male Accessory Gland    1445.1 Adult Carcass    5588.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2511.3) Larval Midgut  (2396.7) Larval Hindgut  (3516.6) Larval Malpighian Tubules  (2168.4) Larval Fat Body  (1378) Larval Salivary Gland  (3423) Larval Trachea  (2159.425) Larval Carcass  (4099.825) Adult Head  (3417.5) Adult Eye  (4618.875) Adult Brain  (3092.8) Adult Thoracic-Abdominal Ganglion  (4240.6) Adult Crop  (3541.2) Adult Midgut  (2549.9) Adult Hindgut  (3867.7) Adult Malpighian Tubules  (3767.2) Adult Fat Body  (4303.6) Adult Salivary Gland  (5765.2) Adult Heart  (4270.45) Adult VirginFemale Spermatheca  (3779.2) Adult InseminatedFemale Spermatheca  (3560.3) Adult Ovary  (2450.8) Adult Testis    454.3 Adult Male Accessory Gland  (1445.1) Adult Carcass  (5588.7) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2511.3) Larval Midgut  (2396.7) Larval Hindgut  (3516.6) Larval Malpighian Tubules  (2168.4) Larval Fat Body  1378 Larval Salivary Gland  (3423) Larval Trachea  (2159.425) Larval Carcass  (4099.825) Adult Head  (3417.5) Adult Eye  (4618.875) Adult Brain  (3092.8) Adult Thoracic-Abdominal Ganglion  (4240.6) Adult Crop  (3541.2) Adult Midgut  (2549.9) Adult Hindgut  (3867.7) Adult Malpighian Tubules  (3767.2) Adult Fat Body  (4303.6) Adult Salivary Gland  (5765.2) Adult Heart  (4270.45) Adult VirginFemale Spermatheca  (3779.2) Adult InseminatedFemale Spermatheca  (3560.3) Adult Ovary  (2450.8) Adult Testis    454.3 Adult Male Accessory Gland  1445.1 Adult Carcass  (5588.7) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2511.3 Larval Midgut    2396.7 Larval Hindgut    3516.6 Larval Malpighian Tubules    2168.4 Larval Fat Body    1378 Larval Salivary Gland    3423 Larval Trachea    2159.425 Larval Carcass    4099.825 Adult Head    3417.5 Adult Eye    4618.875 Adult Brain    3092.8 Adult Thoracic-Abdominal Ganglion    4240.6 Adult Crop    3541.2 Adult Midgut    2549.9 Adult Hindgut    3867.7 Adult Malpighian Tubules    3767.2 Adult Fat Body    4303.6 Adult Salivary Gland    5765.2 Adult Heart    4270.45 Adult VirginFemale Spermatheca    3779.2 Adult InseminatedFemale Spermatheca    3560.3 Adult Ovary    2450.8 Adult Testis    454.3 Adult Male Accessory Gland    1445.1 Adult Carcass    5588.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    3417.5   NA  Eye    4618.875   NA  Brain    3092.8   2511.3  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    4240.6   NA  Crop    3541.2   2396.7  Midgut    2549.9   3516.6  Hindgut    3867.7   2168.4  Malpighian Tubules    3767.2   1378  Fat Body    4303.6   3423  Salivary Gland    5765.2   NA  Heart    4270.45   2159.425  Trachea    NA   NA  VirginFemale Spermatheca    3779.2   NA  InseminatedFemale Spermatheca    3560.3   NA  Ovary    2450.8   NA  Testis    454.3   NA  Male Accessory Gland    1445.1   4099.825  Carcass    5588.7 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    359 central nervous system, larvae L3    354 central nervous system, pupae P8    503 head, virgin 1-day female    1374 head, virgin 4-day female    501 head, virgin 20-day female    309 head, mated 1-day female    1017 head, mated 4-day female    390 head, mated 20-day female    310 head, mated 1-day male    1181 head, mated 4-day male    573 head, mated 20-day male    446 salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    49 digestive system, larvae L3 wandering    151 digestive system, 1-day adult    400 digestive system, 4-day adult    413 digestive system, 20-day adult    252 fat body, larvae L3 wandering    122 fat body, white prepupae    87 fat body, pupae P8    321 carcass, larvae L3 wandering    248 carcass, 1-day adult    2503 carcass, 4-day adult    687 carcass, 20-day adult    410 ovary, virgin 4-day female    587 ovary, mated 4-day female    450 testis, mated 4-day male    100 accessory gland, mated 4-day male    131 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (359) central nervous system, larvae L3  (354) central nervous system, pupae P8  (503) head, virgin 1-day female  (1374) head, virgin 4-day female  (501) head, virgin 20-day female  (309) head, mated 1-day female  (1017) head, mated 4-day female  (390) head, mated 20-day female  (310) head, mated 1-day male  (1181) head, mated 4-day male  (573) head, mated 20-day male  (446) salivary gland, larvae L3 wandering  (27) salivary gland, white prepupae  (49) digestive system, larvae L3 wandering  (151) digestive system, 1-day adult  (400) digestive system, 4-day adult  (413) digestive system, 20-day adult  (252) fat body, larvae L3 wandering  (122) fat body, white prepupae  (87) fat body, pupae P8  (321) carcass, larvae L3 wandering  (248) carcass, 1-day adult  (2503) carcass, 4-day adult  (687) carcass, 20-day adult  (410) ovary, virgin 4-day female  (587) ovary, mated 4-day female  (450) testis, mated 4-day male  (100) accessory gland, mated 4-day male  (131) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (359) central nervous system, larvae L3  (354) central nervous system, pupae P8  (503) head, virgin 1-day female  (1374) head, virgin 4-day female  (501) head, virgin 20-day female  (309) head, mated 1-day female  (1017) head, mated 4-day female  (390) head, mated 20-day female  (310) head, mated 1-day male  (1181) head, mated 4-day male  (573) head, mated 20-day male  (446) salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    49 digestive system, larvae L3 wandering  (151) digestive system, 1-day adult  (400) digestive system, 4-day adult  (413) digestive system, 20-day adult  (252) fat body, larvae L3 wandering  (122) fat body, white prepupae    87 fat body, pupae P8  (321) carcass, larvae L3 wandering  (248) carcass, 1-day adult  (2503) carcass, 4-day adult  (687) carcass, 20-day adult  (410) ovary, virgin 4-day female  (587) ovary, mated 4-day female  (450) testis, mated 4-day male    100 accessory gland, mated 4-day male  (131) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    359 central nervous system, larvae L3    354 central nervous system, pupae P8    503 head, virgin 1-day female    1374 head, virgin 4-day female    501 head, virgin 20-day female    309 head, mated 1-day female    1017 head, mated 4-day female    390 head, mated 20-day female    310 head, mated 1-day male    1181 head, mated 4-day male    573 head, mated 20-day male    446 salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    49 digestive system, larvae L3 wandering    151 digestive system, 1-day adult    400 digestive system, 4-day adult    413 digestive system, 20-day adult    252 fat body, larvae L3 wandering    122 fat body, white prepupae    87 fat body, pupae P8    321 carcass, larvae L3 wandering    248 carcass, 1-day adult    2503 carcass, 4-day adult    687 carcass, 20-day adult    410 ovary, virgin 4-day female    587 ovary, mated 4-day female    450 testis, mated 4-day male    100 accessory gland, mated 4-day male    131 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    359 central nervous system, larvae L3    354 central nervous system, pupae P8    503 head, virgin 1-day female    1374 head, virgin 4-day female    501 head, virgin 20-day female    309 head, mated 1-day female    1017 head, mated 4-day female    390 head, mated 20-day female    310 head, mated 1-day male    1181 head, mated 4-day male    573 head, mated 20-day male    446 salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    49 digestive system, larvae L3 wandering    151 digestive system, 1-day adult    400 digestive system, 4-day adult    413 digestive system, 20-day adult    252 fat body, larvae L3 wandering    122 fat body, white prepupae    87 fat body, pupae P8    321 carcass, larvae L3 wandering    248 carcass, 1-day adult    2503 carcass, 4-day adult    687 carcass, 20-day adult    410 ovary, virgin 4-day female    587 ovary, mated 4-day female    450 testis, mated 4-day male    100 accessory gland, mated 4-day male    131 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (359) central nervous system, larvae L3  (354) central nervous system, pupae P8  (503) head, virgin 1-day female  (1374) head, virgin 4-day female  (501) head, virgin 20-day female  (309) head, mated 1-day female  (1017) head, mated 4-day female  (390) head, mated 20-day female  (310) head, mated 1-day male  (1181) head, mated 4-day male  (573) head, mated 20-day male  (446) salivary gland, larvae L3 wandering  27 salivary gland, white prepupae  (49) digestive system, larvae L3 wandering  (151) digestive system, 1-day adult  (400) digestive system, 4-day adult  (413) digestive system, 20-day adult  (252) fat body, larvae L3 wandering  (122) fat body, white prepupae  (87) fat body, pupae P8  (321) carcass, larvae L3 wandering  (248) carcass, 1-day adult  (2503) carcass, 4-day adult  (687) carcass, 20-day adult  (410) ovary, virgin 4-day female  (587) ovary, mated 4-day female  (450) testis, mated 4-day male  (100) accessory gland, mated 4-day male  (131) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (359) central nervous system, larvae L3  (354) central nervous system, pupae P8  (503) head, virgin 1-day female  (1374) head, virgin 4-day female  (501) head, virgin 20-day female  (309) head, mated 1-day female  (1017) head, mated 4-day female  (390) head, mated 20-day female  (310) head, mated 1-day male  (1181) head, mated 4-day male  (573) head, mated 20-day male  (446) salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    49 digestive system, larvae L3 wandering  (151) digestive system, 1-day adult  (400) digestive system, 4-day adult  (413) digestive system, 20-day adult  (252) fat body, larvae L3 wandering  122 fat body, white prepupae    87 fat body, pupae P8  (321) carcass, larvae L3 wandering  (248) carcass, 1-day adult  (2503) carcass, 4-day adult  (687) carcass, 20-day adult  (410) ovary, virgin 4-day female  (587) ovary, mated 4-day female  (450) testis, mated 4-day male    100 accessory gland, mated 4-day male  131 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    359 central nervous system, larvae L3    354 central nervous system, pupae P8    503 head, virgin 1-day female    1374 head, virgin 4-day female    501 head, virgin 20-day female    309 head, mated 1-day female    1017 head, mated 4-day female    390 head, mated 20-day female    310 head, mated 1-day male    1181 head, mated 4-day male    573 head, mated 20-day male    446 salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    49 digestive system, larvae L3 wandering    151 digestive system, 1-day adult    400 digestive system, 4-day adult    413 digestive system, 20-day adult    252 fat body, larvae L3 wandering    122 fat body, white prepupae    87 fat body, pupae P8    321 carcass, larvae L3 wandering    248 carcass, 1-day adult    2503 carcass, 4-day adult    687 carcass, 20-day adult    410 ovary, virgin 4-day female    587 ovary, mated 4-day female    450 testis, mated 4-day male    100 accessory gland, mated 4-day male    131 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed during early larval stages, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    700 embryo 02-04hr    434 embryo 04-06hr    306 embryo 06-08hr    287 embryo 08-10hr    353 embryo 10-12hr    529 embryo 12-14hr    582 embryo 14-16hr    774 embryo 16-18hr    978 embryo 18-20hr    1109 embryo 20-22hr    1266 embryo 22-24hr    1264 larva L1    1902 larva L2    1937 larva L3 12hr old    1903 larva L3 puffstage 1-2    669 larva L3 puffstage 3-6    366 larva L3 puffstage 7-9    339 white prepupae new    326 white prepupae 12hr    260 white prepupae 24hr    303 pupae 2d postWPP    741 pupae 3d postWPP    2091 pupae 4d postWPP    3031 adult male 01day    2446 adult male 05day    1237 adult male 30day    578 adult female 01day    2321 adult female 05day    952 adult female 30day    804 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (700) embryo 02-04hr  (434) embryo 04-06hr  (306) embryo 06-08hr  (287) embryo 08-10hr  (353) embryo 10-12hr  (529) embryo 12-14hr  (582) embryo 14-16hr  (774) embryo 16-18hr  (978) embryo 18-20hr  (1109) embryo 20-22hr  (1266) embryo 22-24hr  (1264) larva L1  (1902) larva L2  (1937) larva L3 12hr old  (1903) larva L3 puffstage 1-2  (669) larva L3 puffstage 3-6  (366) larva L3 puffstage 7-9  (339) white prepupae new  (326) white prepupae 12hr  (260) white prepupae 24hr  (303) pupae 2d postWPP  (741) pupae 3d postWPP  (2091) pupae 4d postWPP  (3031) adult male 01day  (2446) adult male 05day  (1237) adult male 30day  (578) adult female 01day  (2321) adult female 05day  (952) adult female 30day  (804) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (700) embryo 02-04hr  (434) embryo 04-06hr  (306) embryo 06-08hr  (287) embryo 08-10hr  (353) embryo 10-12hr  (529) embryo 12-14hr  (582) embryo 14-16hr  (774) embryo 16-18hr  (978) embryo 18-20hr  (1109) embryo 20-22hr  (1266) embryo 22-24hr  (1264) larva L1  (1902) larva L2  (1937) larva L3 12hr old  (1903) larva L3 puffstage 1-2  (669) larva L3 puffstage 3-6  (366) larva L3 puffstage 7-9  (339) white prepupae new  (326) white prepupae 12hr  (260) white prepupae 24hr  (303) pupae 2d postWPP  (741) pupae 3d postWPP  (2091) pupae 4d postWPP  (3031) adult male 01day  (2446) adult male 05day  (1237) adult male 30day  (578) adult female 01day  (2321) adult female 05day  (952) adult female 30day  (804) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    700 embryo 02-04hr    434 embryo 04-06hr    306 embryo 06-08hr    287 embryo 08-10hr    353 embryo 10-12hr    529 embryo 12-14hr    582 embryo 14-16hr    774 embryo 16-18hr    978 embryo 18-20hr    1109 embryo 20-22hr    1266 embryo 22-24hr    1264 larva L1    1902 larva L2    1937 larva L3 12hr old    1903 larva L3 puffstage 1-2    669 larva L3 puffstage 3-6    366 larva L3 puffstage 7-9    339 white prepupae new    326 white prepupae 12hr    260 white prepupae 24hr    303 pupae 2d postWPP    741 pupae 3d postWPP    2091 pupae 4d postWPP    3031 adult male 01day    2446 adult male 05day    1237 adult male 30day    578 adult female 01day    2321 adult female 05day    952 adult female 30day    804 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    700 embryo 02-04hr    434 embryo 04-06hr    306 embryo 06-08hr    287 embryo 08-10hr    353 embryo 10-12hr    529 embryo 12-14hr    582 embryo 14-16hr    774 embryo 16-18hr    978 embryo 18-20hr    1109 embryo 20-22hr    1266 embryo 22-24hr    1264 larva L1    1902 larva L2    1937 larva L3 12hr old    1903 larva L3 puffstage 1-2    669 larva L3 puffstage 3-6    366 larva L3 puffstage 7-9    339 white prepupae new    326 white prepupae 12hr    260 white prepupae 24hr    303 pupae 2d postWPP    741 pupae 3d postWPP    2091 pupae 4d postWPP    3031 adult male 01day    2446 adult male 05day    1237 adult male 30day    578 adult female 01day    2321 adult female 05day    952 adult female 30day    804 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (700) embryo 02-04hr  (434) embryo 04-06hr  (306) embryo 06-08hr  (287) embryo 08-10hr  (353) embryo 10-12hr  (529) embryo 12-14hr  (582) embryo 14-16hr  (774) embryo 16-18hr  (978) embryo 18-20hr  (1109) embryo 20-22hr  (1266) embryo 22-24hr  (1264) larva L1  (1902) larva L2  (1937) larva L3 12hr old  (1903) larva L3 puffstage 1-2  (669) larva L3 puffstage 3-6  (366) larva L3 puffstage 7-9  (339) white prepupae new  (326) white prepupae 12hr  (260) white prepupae 24hr  (303) pupae 2d postWPP  (741) pupae 3d postWPP  (2091) pupae 4d postWPP  (3031) adult male 01day  (2446) adult male 05day  (1237) adult male 30day  (578) adult female 01day  (2321) adult female 05day  (952) adult female 30day  (804) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (700) embryo 02-04hr  (434) embryo 04-06hr  (306) embryo 06-08hr  (287) embryo 08-10hr  (353) embryo 10-12hr  (529) embryo 12-14hr  (582) embryo 14-16hr  (774) embryo 16-18hr  (978) embryo 18-20hr  (1109) embryo 20-22hr  (1266) embryo 22-24hr  (1264) larva L1  (1902) larva L2  (1937) larva L3 12hr old  (1903) larva L3 puffstage 1-2  (669) larva L3 puffstage 3-6  (366) larva L3 puffstage 7-9  (339) white prepupae new  (326) white prepupae 12hr  (260) white prepupae 24hr  (303) pupae 2d postWPP  (741) pupae 3d postWPP  (2091) pupae 4d postWPP  (3031) adult male 01day  (2446) adult male 05day  (1237) adult male 30day  (578) adult female 01day  (2321) adult female 05day  (952) adult female 30day  (804) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    700 embryo 02-04hr    434 embryo 04-06hr    306 embryo 06-08hr    287 embryo 08-10hr    353 embryo 10-12hr    529 embryo 12-14hr    582 embryo 14-16hr    774 embryo 16-18hr    978 embryo 18-20hr    1109 embryo 20-22hr    1266 embryo 22-24hr    1264 larva L1    1902 larva L2    1937 larva L3 12hr old    1903 larva L3 puffstage 1-2    669 larva L3 puffstage 3-6    366 larva L3 puffstage 7-9    339 white prepupae new    326 white prepupae 12hr    260 white prepupae 24hr    303 pupae 2d postWPP    741 pupae 3d postWPP    2091 pupae 4d postWPP    3031 adult male 01day    2446 adult male 05day    1237 adult male 30day    578 adult female 01day    2321 adult female 05day    952 adult female 30day    804 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    323 Schneider line 2 Sg4    268 embryonic 1182-4H    164 embryonic GM2    95 embryonic Kc167    194 embryonic S1    321 embryonic S3    414 leg disc CME L1    270 wing disc CME-W2    218 wing disc ML-DmD8    271 wing disc ML-DmD9    259 wing disc ML-DmD16-c3    246 wing disc ML-DmD21    217 wing disc ML-DmD32    296 haltere disc ML-DmD17-c3    442 eye-antennal disc ML-DmD11    406 antennal disc ML-DmD20-c5    238 mixed discs ML-DmD4-c1    309 CNS ML-DmBG1-c1    283 CNS ML-DmBG2-c2    197 tumorous blood cells mbn2    217 ovary fGS/OSS    257 ovary OSC    400 ovary OSS    195 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (323) Schneider line 2 Sg4  (268) embryonic 1182-4H  (164) embryonic GM2  (95) embryonic Kc167  (194) embryonic S1  (321) embryonic S3  (414) leg disc CME L1  (270) wing disc CME-W2  (218) wing disc ML-DmD8  (271) wing disc ML-DmD9  (259) wing disc ML-DmD16-c3  (246) wing disc ML-DmD21  (217) wing disc ML-DmD32  (296) haltere disc ML-DmD17-c3  (442) eye-antennal disc ML-DmD11  (406) antennal disc ML-DmD20-c5  (238) mixed discs ML-DmD4-c1  (309) CNS ML-DmBG1-c1  (283) CNS ML-DmBG2-c2  (197) tumorous blood cells mbn2  (217) ovary fGS/OSS  (257) ovary OSC  (400) ovary OSS  (195) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (323) Schneider line 2 Sg4  (268) embryonic 1182-4H  (164) embryonic GM2    95 embryonic Kc167  (194) embryonic S1  (321) embryonic S3  (414) leg disc CME L1  (270) wing disc CME-W2  (218) wing disc ML-DmD8  (271) wing disc ML-DmD9  (259) wing disc ML-DmD16-c3  (246) wing disc ML-DmD21  (217) wing disc ML-DmD32  (296) haltere disc ML-DmD17-c3  (442) eye-antennal disc ML-DmD11  (406) antennal disc ML-DmD20-c5  (238) mixed discs ML-DmD4-c1  (309) CNS ML-DmBG1-c1  (283) CNS ML-DmBG2-c2  (197) tumorous blood cells mbn2  (217) ovary fGS/OSS  (257) ovary OSC  (400) ovary OSS  (195) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    323 Schneider line 2 Sg4    268 embryonic 1182-4H    164 embryonic GM2    95 embryonic Kc167    194 embryonic S1    321 embryonic S3    414 leg disc CME L1    270 wing disc CME-W2    218 wing disc ML-DmD8    271 wing disc ML-DmD9    259 wing disc ML-DmD16-c3    246 wing disc ML-DmD21    217 wing disc ML-DmD32    296 haltere disc ML-DmD17-c3    442 eye-antennal disc ML-DmD11    406 antennal disc ML-DmD20-c5    238 mixed discs ML-DmD4-c1    309 CNS ML-DmBG1-c1    283 CNS ML-DmBG2-c2    197 tumorous blood cells mbn2    217 ovary fGS/OSS    257 ovary OSC    400 ovary OSS    195 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    323 Schneider line 2 Sg4    268 embryonic 1182-4H    164 embryonic GM2    95 embryonic Kc167    194 embryonic S1    321 embryonic S3    414 leg disc CME L1    270 wing disc CME-W2    218 wing disc ML-DmD8    271 wing disc ML-DmD9    259 wing disc ML-DmD16-c3    246 wing disc ML-DmD21    217 wing disc ML-DmD32    296 haltere disc ML-DmD17-c3    442 eye-antennal disc ML-DmD11    406 antennal disc ML-DmD20-c5    238 mixed discs ML-DmD4-c1    309 CNS ML-DmBG1-c1    283 CNS ML-DmBG2-c2    197 tumorous blood cells mbn2    217 ovary fGS/OSS    257 ovary OSC    400 ovary OSS    195 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (323) Schneider line 2 Sg4  (268) embryonic 1182-4H  (164) embryonic GM2  (95) embryonic Kc167  (194) embryonic S1  (321) embryonic S3  (414) leg disc CME L1  (270) wing disc CME-W2  (218) wing disc ML-DmD8  (271) wing disc ML-DmD9  (259) wing disc ML-DmD16-c3  (246) wing disc ML-DmD21  (217) wing disc ML-DmD32  (296) haltere disc ML-DmD17-c3  (442) eye-antennal disc ML-DmD11  (406) antennal disc ML-DmD20-c5  (238) mixed discs ML-DmD4-c1  (309) CNS ML-DmBG1-c1  (283) CNS ML-DmBG2-c2  (197) tumorous blood cells mbn2  (217) ovary fGS/OSS  (257) ovary OSC  (400) ovary OSS  (195) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (323) Schneider line 2 Sg4  (268) embryonic 1182-4H  (164) embryonic GM2    95 embryonic Kc167  (194) embryonic S1  (321) embryonic S3  (414) leg disc CME L1  (270) wing disc CME-W2  (218) wing disc ML-DmD8  (271) wing disc ML-DmD9  (259) wing disc ML-DmD16-c3  (246) wing disc ML-DmD21  (217) wing disc ML-DmD32  (296) haltere disc ML-DmD17-c3  (442) eye-antennal disc ML-DmD11  (406) antennal disc ML-DmD20-c5  (238) mixed discs ML-DmD4-c1  (309) CNS ML-DmBG1-c1  (283) CNS ML-DmBG2-c2  (197) tumorous blood cells mbn2  (217) ovary fGS/OSS  (257) ovary OSC  (400) ovary OSS  (195) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    323 Schneider line 2 Sg4    268 embryonic 1182-4H    164 embryonic GM2    95 embryonic Kc167    194 embryonic S1    321 embryonic S3    414 leg disc CME L1    270 wing disc CME-W2    218 wing disc ML-DmD8    271 wing disc ML-DmD9    259 wing disc ML-DmD16-c3    246 wing disc ML-DmD21    217 wing disc ML-DmD32    296 haltere disc ML-DmD17-c3    442 eye-antennal disc ML-DmD11    406 antennal disc ML-DmD20-c5    238 mixed discs ML-DmD4-c1    309 CNS ML-DmBG1-c1    283 CNS ML-DmBG2-c2    197 tumorous blood cells mbn2    217 ovary fGS/OSS    257 ovary OSC    400 ovary OSS    195 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    250 cold shock, 4-day adult    159 heat shock, 4-day adult    623 Cadmium 50 mM 6 hrs, larvae L3    447 Cadmium 50 mM 12 hrs, larvae L3    382 Cadmium 50 mM 48 hrs, 4-day adult    650 Cadmium 100 mM 48 hrs, 4-day adult    384 Copper 0.5 mM 12 hrs, larvae L3    377 Copper 15 mM 48 hrs, 4-day adult    488 Zinc 5 mM 12 hrs, larvae L3    306 Zinc 4.5 mM 48 hrs, 4-day adult    422 Ethanol 2.5% 3 hrs, larvae L3    391 Ethanol 5% 3 hrs, larvae L3    735 Ethanol 10% 3 hrs, larvae L3    604 Caffeine 1.5 mg/ml 4 hrs, larvae L3    674 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    404 Caffeine 25 mg/ml 48 hrs, 4-day adult    241 Paraquat 5 mM 48 hrs, 4-day adult    466 Paraquat 10 mM 48 hrs, 4-day adult    354 Rotenone 2 μg 12 hrs, larvae L3    643 Rotenone 8 μg 12 hrs, larvae L3    755 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (250) cold shock, 4-day adult  (159) heat shock, 4-day adult  (623) Cadmium 50 mM 6 hrs, larvae L3  (447) Cadmium 50 mM 12 hrs, larvae L3  (382) Cadmium 50 mM 48 hrs, 4-day adult  (650) Cadmium 100 mM 48 hrs, 4-day adult  (384) Copper 0.5 mM 12 hrs, larvae L3  (377) Copper 15 mM 48 hrs, 4-day adult  (488) Zinc 5 mM 12 hrs, larvae L3  (306) Zinc 4.5 mM 48 hrs, 4-day adult  (422) Ethanol 2.5% 3 hrs, larvae L3  (391) Ethanol 5% 3 hrs, larvae L3  (735) Ethanol 10% 3 hrs, larvae L3  (604) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (674) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (404) Caffeine 25 mg/ml 48 hrs, 4-day adult  (241) Paraquat 5 mM 48 hrs, 4-day adult  (466) Paraquat 10 mM 48 hrs, 4-day adult  (354) Rotenone 2 μg 12 hrs, larvae L3  (643) Rotenone 8 μg 12 hrs, larvae L3  (755) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (250) cold shock, 4-day adult  (159) heat shock, 4-day adult  (623) Cadmium 50 mM 6 hrs, larvae L3  (447) Cadmium 50 mM 12 hrs, larvae L3  (382) Cadmium 50 mM 48 hrs, 4-day adult  (650) Cadmium 100 mM 48 hrs, 4-day adult  (384) Copper 0.5 mM 12 hrs, larvae L3  (377) Copper 15 mM 48 hrs, 4-day adult  (488) Zinc 5 mM 12 hrs, larvae L3  (306) Zinc 4.5 mM 48 hrs, 4-day adult  (422) Ethanol 2.5% 3 hrs, larvae L3  (391) Ethanol 5% 3 hrs, larvae L3  (735) Ethanol 10% 3 hrs, larvae L3  (604) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (674) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (404) Caffeine 25 mg/ml 48 hrs, 4-day adult  (241) Paraquat 5 mM 48 hrs, 4-day adult  (466) Paraquat 10 mM 48 hrs, 4-day adult  (354) Rotenone 2 μg 12 hrs, larvae L3  (643) Rotenone 8 μg 12 hrs, larvae L3  (755) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    250 cold shock, 4-day adult    159 heat shock, 4-day adult    623 Cadmium 50 mM 6 hrs, larvae L3    447 Cadmium 50 mM 12 hrs, larvae L3    382 Cadmium 50 mM 48 hrs, 4-day adult    650 Cadmium 100 mM 48 hrs, 4-day adult    384 Copper 0.5 mM 12 hrs, larvae L3    377 Copper 15 mM 48 hrs, 4-day adult    488 Zinc 5 mM 12 hrs, larvae L3    306 Zinc 4.5 mM 48 hrs, 4-day adult    422 Ethanol 2.5% 3 hrs, larvae L3    391 Ethanol 5% 3 hrs, larvae L3    735 Ethanol 10% 3 hrs, larvae L3    604 Caffeine 1.5 mg/ml 4 hrs, larvae L3    674 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    404 Caffeine 25 mg/ml 48 hrs, 4-day adult    241 Paraquat 5 mM 48 hrs, 4-day adult    466 Paraquat 10 mM 48 hrs, 4-day adult    354 Rotenone 2 μg 12 hrs, larvae L3    643 Rotenone 8 μg 12 hrs, larvae L3    755 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    250 cold shock, 4-day adult    159 heat shock, 4-day adult    623 Cadmium 50 mM 6 hrs, larvae L3    447 Cadmium 50 mM 12 hrs, larvae L3    382 Cadmium 50 mM 48 hrs, 4-day adult    650 Cadmium 100 mM 48 hrs, 4-day adult    384 Copper 0.5 mM 12 hrs, larvae L3    377 Copper 15 mM 48 hrs, 4-day adult    488 Zinc 5 mM 12 hrs, larvae L3    306 Zinc 4.5 mM 48 hrs, 4-day adult    422 Ethanol 2.5% 3 hrs, larvae L3    391 Ethanol 5% 3 hrs, larvae L3    735 Ethanol 10% 3 hrs, larvae L3    604 Caffeine 1.5 mg/ml 4 hrs, larvae L3    674 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    404 Caffeine 25 mg/ml 48 hrs, 4-day adult    241 Paraquat 5 mM 48 hrs, 4-day adult    466 Paraquat 10 mM 48 hrs, 4-day adult    354 Rotenone 2 μg 12 hrs, larvae L3    643 Rotenone 8 μg 12 hrs, larvae L3    755 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (250) cold shock, 4-day adult  (159) heat shock, 4-day adult  (623) Cadmium 50 mM 6 hrs, larvae L3  (447) Cadmium 50 mM 12 hrs, larvae L3  (382) Cadmium 50 mM 48 hrs, 4-day adult  (650) Cadmium 100 mM 48 hrs, 4-day adult  (384) Copper 0.5 mM 12 hrs, larvae L3  (377) Copper 15 mM 48 hrs, 4-day adult  (488) Zinc 5 mM 12 hrs, larvae L3  (306) Zinc 4.5 mM 48 hrs, 4-day adult  (422) Ethanol 2.5% 3 hrs, larvae L3  (391) Ethanol 5% 3 hrs, larvae L3  (735) Ethanol 10% 3 hrs, larvae L3  (604) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (674) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (404) Caffeine 25 mg/ml 48 hrs, 4-day adult  (241) Paraquat 5 mM 48 hrs, 4-day adult  (466) Paraquat 10 mM 48 hrs, 4-day adult  (354) Rotenone 2 μg 12 hrs, larvae L3  (643) Rotenone 8 μg 12 hrs, larvae L3  (755) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (250) cold shock, 4-day adult  (159) heat shock, 4-day adult  (623) Cadmium 50 mM 6 hrs, larvae L3  (447) Cadmium 50 mM 12 hrs, larvae L3  (382) Cadmium 50 mM 48 hrs, 4-day adult  (650) Cadmium 100 mM 48 hrs, 4-day adult  (384) Copper 0.5 mM 12 hrs, larvae L3  (377) Copper 15 mM 48 hrs, 4-day adult  (488) Zinc 5 mM 12 hrs, larvae L3  (306) Zinc 4.5 mM 48 hrs, 4-day adult  (422) Ethanol 2.5% 3 hrs, larvae L3  (391) Ethanol 5% 3 hrs, larvae L3  (735) Ethanol 10% 3 hrs, larvae L3  (604) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (674) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (404) Caffeine 25 mg/ml 48 hrs, 4-day adult  (241) Paraquat 5 mM 48 hrs, 4-day adult  (466) Paraquat 10 mM 48 hrs, 4-day adult  (354) Rotenone 2 μg 12 hrs, larvae L3  (643) Rotenone 8 μg 12 hrs, larvae L3  (755) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    250 cold shock, 4-day adult    159 heat shock, 4-day adult    623 Cadmium 50 mM 6 hrs, larvae L3    447 Cadmium 50 mM 12 hrs, larvae L3    382 Cadmium 50 mM 48 hrs, 4-day adult    650 Cadmium 100 mM 48 hrs, 4-day adult    384 Copper 0.5 mM 12 hrs, larvae L3    377 Copper 15 mM 48 hrs, 4-day adult    488 Zinc 5 mM 12 hrs, larvae L3    306 Zinc 4.5 mM 48 hrs, 4-day adult    422 Ethanol 2.5% 3 hrs, larvae L3    391 Ethanol 5% 3 hrs, larvae L3    735 Ethanol 10% 3 hrs, larvae L3    604 Caffeine 1.5 mg/ml 4 hrs, larvae L3    674 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    404 Caffeine 25 mg/ml 48 hrs, 4-day adult    241 Paraquat 5 mM 48 hrs, 4-day adult    466 Paraquat 10 mM 48 hrs, 4-day adult    354 Rotenone 2 μg 12 hrs, larvae L3    643 Rotenone 8 μg 12 hrs, larvae L3    755 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_15 mE1_20_mRNA_expression_cluster_01
External Data & Images
Linkouts	BDGP expression data • GM13193 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039830 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1746-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG1746 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG1746 Class Mutagen Stocks Known lesion CG1746KG01914 2 -- CG1746BG01889 P-element activity 0 -- CG1746EP3264 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG1746 Class Mutagen Stocks Known lesion CG1746GL00390 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG1746KK108875 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG1746GD4650 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CG1746NIG.1746R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6218 (Ryder, 2004.4.26) Df(3R)Exel7379 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4650} NA P{KK108875} NA P{NIG.1746R} NA P{TRiP.GL00390} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG1746EP3264 NA miscellaneous insertions P{GT1}CG1746BG01889 NA P{SUPor-P}CG1746KG01914 NA P{SUPor-P}KG05897 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
hydrogen-exporting ATPase activity, phosphorylative mechanism inferred from sequence or structural similarity with UniProtKB:P05496 AND inferred from sequence or structural similarity with UniProt:P48201 AND inferred from sequence or structural similarity with UniProt:Q06055 (Sardiello et al., 2003.6.11) non-traceable author statement (FlyBase, 1992-)
Biological Process
CV term Evidence References
ATP hydrolysis coupled proton transport inferred from electronic annotation with InterPro:IPR002379 (FlyBase Curators et al., 2004-) ATP synthesis coupled proton transport inferred from electronic annotation with InterPro:IPR000454 (FlyBase Curators et al., 2004-) proton transport inferred from sequence or structural similarity with UniProtKB:P05496 AND inferred from sequence or structural similarity with UniProt:P48201 AND inferred from sequence or structural similarity with UniProt:Q06055 (Sardiello et al., 2003.6.11)
Cellular Component
CV term Evidence References
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) inferred from sequence or structural similarity with UniProtKB:P05496 AND inferred from sequence or structural similarity with UniProt:P48201 AND inferred from sequence or structural similarity with UniProt:Q06055 (Sardiello et al., 2003.6.11)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG1746 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68538 DroID - A comprehensive database of gene and protein interactions. • FBgn0039830 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43693
Orthologs
OrthoDB Orthologs (63) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG647GF3 Dipteran inclusive ortholog search EOG6T4D52 Insect inclusive ortholog search EOG6N5TTW Arthropod inclusive ortholog search EOG6866WG Metazoa inclusive ortholog search EOG6TN3XW
Orthologs in Drosophila Species (EOG647GF3)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG1746     Drosophila simulans   Dsim\GD16524 Y   Drosophila sechellia   Dsec\GM12097 Y   Drosophila erecta   Dere\GG11879 Y   Drosophila yakuba   Dyak\GE23327 Y   Drosophila ananassae   Dana\GF16589 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA14517 Y   Drosophila persimilis   Dper\GL13949 Y   Drosophila willistoni   Dwil\GK22551 Y   Drosophila virilis   Dvir\GJ10646 Y   Drosophila mojavensis   Dmoj\GI10430 Y   Drosophila grimshawi   Dgri\GH14335 Y
Orthologs in non-Drosophila Dipterans (EOG6T4D52)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL006256   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL012740   Anopheles gambiae Malaria mosquito  Agam\AGAP000523   Anopheles gambiae Malaria mosquito  Agam\AGAP002105   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ008101
Orthologs in non-Dipteran Insects (EOG6N5TTW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\ATP5G2   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012157   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22503   Atta cephalotes Leafcutter ant  Acep\ACEP10622   Camponotus floridanus Florida carpenter ant  Cflo\CFLO19193   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14953   Linepithema humile Argentine ant  Lhum\LH23160   Pogonomyrmex barbatus Red harvester ant  Pbar\CG:02550062   Pogonomyrmex barbatus Red harvester ant  Pbar\CG:02550078   Solenopsis invicta Red fire ant  Sinv\SINV14132   Acyrthosiphon pisum Pea aphid  Apim\ACYPI000030   Acyrthosiphon pisum Pea aphid  Apim\ACYPI072805   Bombyx mori Silkmoth  Bmor\BGIBMGA006412   Pediculus humanus Human body louse  Phum\PHUM412530   Tribolium castaneum Red flour beetle  Tcas\GLEAN_15253   Tribolium castaneum Red flour beetle  Tcas\TC011455   Tribolium castaneum Red flour beetle  Tcas\GLEAN_15454
Orthologs in non-Insect Arthropods (EOG6866WG)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\RAG2   Ixodes scapularis Deer tick  Isca\ISCW010495
Orthologs in non-Arthropod Metazoa (EOG6TN3XW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\Y82E9BR.3   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013052gn   Danio rerio Zebrafish  Drer\zgc:73293   Danio rerio Zebrafish  Drer\ENSDARG00000017775   Danio rerio Zebrafish  Drer\atp5g   Xenopus tropicalis Western clawed frog  Xtro\atp5g3   Xenopus tropicalis Western clawed frog  Xtro\atp5g1   Gallus gallus Domestic chicken  Ggal\ENSGALG00000003041   Gallus gallus Domestic chicken  Ggal\ATP5G3   Gallus gallus Domestic chicken  Ggal\ATP5G1   Mus musculus House mouse  Mmus\Atp5g1   Mus musculus House mouse  Mmus\Atp5g2   Mus musculus House mouse  Mmus\Atp5g3   Mus musculus House mouse  Mmus\Gm17271   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000012129   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000020112   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000018045   Rattus norvegicus Norway rat  Rnor\Atp5g1   Rattus norvegicus Norway rat  Rnor\LOC689961   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000024308   Rattus norvegicus Norway rat  Rnor\Atp5g3   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000026663   Rattus norvegicus Norway rat  Rnor\Atp5g2   Rattus norvegicus Norway rat  Rnor\RGD1559629   Homo sapiens Human  Hsap\ENSG00000135390   Homo sapiens Human  Hsap\ATP5G1   Homo sapiens Human  Hsap\ATP5G3
Human Orthologs (3)
Gene OMIM HGNC Hsap\ENSG00000135390     Hsap\ATP5G1     Hsap\ATP5G3
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD16524 Drosophila sechellia Dsec\GM12097 Drosophila erecta Dere\GG11879 Drosophila yakuba Dyak\GE23327 Drosophila ananassae Dana\GF16589 Drosophila pseudoobscura pseudoobscura Dpse\GA14517 Drosophila persimilis Dper\GL13949 Drosophila willistoni Dwil\GK22551 Drosophila virilis Dvir\GJ10646 Drosophila mojavensis Dmoj\GI10430 Drosophila grimshawi Dgri\GH14335
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	35464 y1 sc* v1; P{TRiP.GL00390}attP2 13923 y1; ry506 P{SUPor-P}CG1746KG01914/TM3, Sb1 Ser1
Kyoto	111568 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{neoFRT}82B P{SUPor-P}CG1746KG01914/TM6B, P{Car20y}TPN1, Tb1
VDRC	v106834 P{KK108875}VIE-260B
Genomic Clones ( 1 )
	BACR30B13 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 561 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM13193
Other clones	AF171841 FI17004 MIP02330 MIP07538 yak-em_CG1746
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT12992 AT24768 GH01720 GH03626 GH03650 GH03783 GH04148 GH04239 GH04741 GH04827 GH05931 GH07004 GH07365 GH08089 GH08842 GH09601 GH09834 GH13283 GH14249 GH18203 GH21670 GH22539 GH22812 GH24540 GH24668 GH28706 GH28748 GH28783 GM01022 GM01038 GM01139 GM01962 GM02479 GM02883 GM03450 GM04044 GM04130 GM06841 GM07445 GM08251 GM08704 GM09592 GM10164 GM14420 GM14542 GM15169 GM21096 GM22227 GM24006 GM27579 LD03432 LD03977 LD09271 LD29128 LD31669 LP01296 LP02436 LP02889 LP03134 LP03768 LP04260 LP08804 LP09812 LP09933 LP14978 LP16266 LP24248 RE05469 RE07203 RE08096 RE09790 RE28705 RE30336 RE30760 RE32934 RE35340 RE46507 RE51922 RE57376 RE69049 RE72122 RH13970 RH23841 RH38007 RH38412 RH38611 RH39028 RH45004 RH50807 RH52121 RH52751 RH53217 RH53235 RH53746 RH54611 RH54695 RH54707 RH54734 RH55626 RH55918 RH56283 RH56296 RH56719 RH56731 RH56783 RH57768 RH58579 RH58585 RH58593 RH58720 RH59221 RH59862 RH59896 RH59954 RH60092 RH60114 RH60283 RH60823 RH60854 RH63915 RH66358 RH66562 RH69044 RH69223 RH69228 RH69382 SD11869 SD14861 SD23744 SD26732 SD28236
Other clones	520 7931 38680 44341 76201 76412 82596 97379 107837 108866 119502 190483 190997 194671 473652 524248 542700 557864 561864 568971 bs52h03 bs80h04 CK01.1D.A6 CK01.89B.G8 CK01.99B.B12 Dmel_dig_001768_0636_0358 Dmel_dig_002909_0589_1389 Dmel_dig_003464_0689_1707 Dmel_dig_003763_0705_1892 Dmel_dig_004200_0602_0701 Dmel_dig_004557_0588_1730 Dmel_dig_004742_0640_2782 Dmel_dig_004879_0679_1532 Dmel_dig_005043_0683_3488 Dmel_dig_005347_0636_3543 Dmel_dig_005726_0658_3197 Dmel_dig_005863_0683_2835 Dmel_dig_007216_0607_2422 Dmel_dig_007253_0708_1916 Dmel_dig_007308_0586_1492 Dmel_dig_007440_0643_3058 Dmel_dig_007467_0716_0927 Dmel_dig_007760_0684_1184 Dmel_dig_007933_0659_2340 Dmel_dig_009064_0621_0435 Dmel_dig_009446_0633_3073 Dmel_dig_009678_0585_2325 Dmel_dig_009806_0584_3701 Dmel_dig_010077_0673_2299 Dmel_dig_010432_0626_1144 Dmel_dig_011016_0673_3095 Dmel_dig_011072_0604_2265 Dmel_dig_011111_0666_3122 Dmel_dig_012014_0632_2293 Dmel_dig_013184_0661_2819 Dmel_dig_014189_0604_2090 Dmel_dig_014473_0684_3190 Dmel_dig_014973_0713_3634 Dmel_dig_015823_0686_1294 Dmel_dig_015893_0654_1371 Dmel_dig_016015_0702_3541 Dmel_dig_016298_0595_2000 Dmel_dig_016595_0621_1320 Dmel_dig_016874_0676_0655 Dmel_dig_018045_0677_0775 Dmel_dig_018729_0700_0875 Dmel_dig_018802_0685_1817 Dmel_dig_018841_0600_1848 Dmel_dig_019554_0602_1935 Dmel_dig_019646_0614_3417 Dmel_dig_020409_0592_3272 Dmel_neb_000888_0097_3574 Dmel_neb_004224_0896_0291 Dmel_neb_005416_0365_2607 Dmel_neb_007349_0951_3687 Dmel_neb_007459_0903_1570 Dmel_neb_008299_0693_3519 Dmel_neb_008816_0591_0374 Dmel_neb_008979_0615_3597 Dmel_neb_010935_0567_2554 Dmel_neb_011103_0940_0304 Dmel_neb_011240_0903_3047 Dmel_neb_011598_0330_1041 Dmel_neb_011933_0869_2303 Dmel_neb_012125_0951_1287 Dmel_neb_012730_0672_2478 Dmel_neb_012910_0911_1470 Dmel_neb_012936_0617_1973 Dmel_neb_013258_0434_0703 Dmel_neb_013589_0890_1581 Dmel_neb_013816_0930_3429 Dmel_neb_014403_0835_2700 Dmel_neb_014724_0317_2275 Dmel_neb_014837_0872_3165 Dmel_neb_015280_0175_2970 Dmel_neb_015930_0568_3162 Dmel_neb_015948_0828_0623 EC12249 EC14825 EC17339 EC23649 EC26084 EC29949 EC36659 EC42649 EK008135 EK070243 EK076440 EK085405 EK106128 EK163460 EK196748 EK206557 EK216045 EK234144 EK235117 EK248304 EK292817 EK297704 EK298050 EN00439 EN05027 EN09508 EN11137 EN12542 EN13209 EN14257 EP13407 FGA005B04 FGA005B07 FGA007C03 FGA010F01 FGC001G09 FGC002H10 FGC003D04 FGC003E05 FGC005B06 FGC006F03 FGC008D06 FGC014H10 FGC016B08 FGC017G09 FGC019E08 FGC029E09 FGC031A07 FGC033E08 FGH001B05 FGH102F01 FGH103H04 FGH104F07 FGH108C05 FGH108D10 FGH110C02 FGH110C10 FGH110F07 FGH111A09 FGH111B03 FGH112D06 FGH112F11 FGH113B11 FGH113F12 FGH114G11 FGH116D05 FGH117B08 FGH117H04 FGH118H06 FGH119C10 FGH120C01 FGH120E06 FGH120F03 FGH121G10 FGH122C12 FGH122D09 FGH124E02 FGH124E08 FGH124H12 FGH125B04 FGH125C08 FGH125F06 FGH125G03 FGH126C12 FGH126D05 FGH126E01 FGH128D03 FGH129C12 FGM003E11 FGM004B05 FGM004E02 FGM102C03 FGM105H01 FGM207F08 FGM208F12 FGM209C09 FGM209E12 FGM210B07 FGM210H10 FGM212D12 FGM212H03 FGM213H09 FGM215F07 FGM217D01 FGM219A05 FGM221B09 FGM224D10 FGM224E11 FGM224H04 FGM226A10 FGM227F01 FGM228G03 FGM230E09 FGM231B01 FGM233D09 FGM234B06 FGM235A12 FGM236A09 FGM236B07 FGM236F03 FGM304D05 FGM305F04 FGM306A04 FGM307H10 FGM314G11 FGM317A03 FGM317B07 FGM318B08 FGM318B10 FGM318C08 FGM319B12 FGM319E03 FGM323F01 GH07038 GH13770 GH25144 HL01291 HL04321 IP03308 IP03408 IP03508 IP09549 IP11091 IP12407 IP12607 IP14083 IP14183 IP14383 LD31638 RE01372 RE02238 RE04070 RE05651 RE05958 RE06461 RE08090 RE11110 RE11458 RE11506 RE12248 RE13537 RE18509 RE20209 RE23684 RE24404 RE25338 RE25561 RE25577 RE26495 RE27205 RE28963 RE31195 RE31314 RE32287 RE34384 RE34609 RE35133 RE36770 RE37389 RE37623 RE38172 RE38757 RE39225 RE40664 RE40704 RE41045 RE43653 RE44228 RE45048 RE48695 RE48696 RE49104 RE51495 RE51496 RE54411 RE55460 RE59164 RE60411 RE62460 RE63579 RE64094 RE69006 RH01710 RH01934 RH02483 RH02560 RH03829 RH04045 RH04668 RH04694 RH04759 RH05150 RH05332 RH05452 RH05724 RH06220 RH06232 RH06686 RH07609 RH07610 RH08525 RH08529 RH10130 RH10146 RH10204 RH10674 RH10694 RH11003 RH11332 RH11435 RH11542 RH12044 RH12180 RH14192 RH15968 RH16211 RH16810 RH19089 RH19104 RH21434 RH21470 RH22380 RH22507 RH23447 RH23607 RH23663 RH25469 RH25953 RH26352 RH26866 RH27714 RH28296 RH29324 RH29541 RH29701 RH29986 RH30615 RH32718 RH33072 RH33631 RH33719 RH33914 RH34359 RH34605 RH34667 RH35117 RH35962 RH36880 RH36905 RH37153 RH37768 RH37871 RH38096 RH38661 RH39356 RH39562 RH39695 RH39751 RH40472 RH40496 RH40728 RH40729 RH42013 RH42114 RH42454 RH42517 RH42917 RH43003 RH43095 RH43218 RH43492 RH43627 RH43872 RH44228 RH45217 RH46170 RH46177 RH46831 RH47061 RH47134 RH47555 RH47668 RH47773 RH48224 RH48801 RH48825 RH49439 RH49979 RH50327 RH50337 RH51894 RH59802 RH60582 RH61326 RH61916 RH63429 RH68141 RH69838 RH70376 RH70621 RH70701 RH71162 RH72624 RH72950 RH73341 RH74079 RH74631
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039830 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43693
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG1746 anon-EST:Posey224 (Bayraktaroglu, 2000.11.2)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143595 NM_170543 NM_170544 NM_001260453 NM_001260454 NM_001260455 RefSeq (Proteins) • NP_651852 NP_733422 NP_733423 NP_001247382 NP_001247383 NP_001247384 DDBJ / EMBL / GenBank • AA803445 AAF57131 AAN14267 AAN14268 AF171841 AFH06698 AFH06699 AFH06700 AFH06701 AI513225 Entrez Gene - A searchable database of RefSeq genes. • 43693 UniProtKB/TrEMBL • Q6NN09
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • ATPase, F0 complex, subunit C (IPR000454) V-ATPase proteolipid subunit C-like domain (IPR002379) ATPase, F0 complex, subunit C, DCCD-binding site (IPR020537) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME01746 BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GM13193
Linkouts
	BioGRID - A database of protein and genetic interactions • 68538 DroID - A comprehensive database of gene and protein interactions. • FBgn0039830 DRSC - Results from RNAi screens. • FBgn0039830 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039830 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1746-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039830 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43693 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43693 modMine - Data generated by the modENCODE project. • FBgn0039830
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	anon-EST:Posey224   CG1746 (Porcelli et al., 2007, Tripoli et al., 2005, Levis et al., 2011.12.16, Keleman et al., 2009.8.5, Ni et al., 2011.7.19, Reis et al., 2010, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym	ATP synthase Lipid-binding protein P1 (Tripoli et al., 2005) F0/F1 ATP synthase Lipid-binding protein (Porcelli et al., 2007)
Secondary FlyBase IDs
	FBgn0027724
References ( 27 )
Generate a list of	All references relating to this gene ( 27 )
List References by type	Research paper  ( 6 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 10 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 1 )
	Palgi et al., 2012, BMC Genomics 13: 134 Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes. [FBrf0218515] Show all research papers ...