dCycG
a transcriptional regulator that interacts with the chromatin factor Corto and controls expression of the homeotic gene Abdominal B - controls developmental stability by ensuring compensatory processes between cell growth and cell proliferation
Please see the JBrowse view of Dmel\CycG for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.55
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Gene model reviewed during 5.53
Interacts with corto (PubMed:18286205). Interacts with the cyclin-dependent kinases Cdk2 and Cdk4 (PubMed:21311225). Interacts with Brca2 and Rad9 (PubMed:22976300). Interacts with polycomb protein Asx (PubMed:25995770). Interacts with protein phosphatase 2A subunit wdb (PubMed:26274446).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CycG using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: in oocyte
JBrowse - Visual display of RNA-Seq signals
View Dmel\CycG in JBrowse3-102
3-99.1
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
CycG has a role in an early step of meiotic recombination repair.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Identification: as a protein that interacts with H in a yeast two-hybrid screen.
Overexpression of CycG during eye imaginal development results in rough eyes that are smaller than normal.
Source for merge of: CycG anon- EST:Liang-2.24 anon- EST:Liang-1.25
Source for identity of: CycG CG11525