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Gene Dmel\CG1815

General Information
Symbol	Dmel\CG1815	Species	D. melanogaster
Name		Annotation symbol	CG1815
Feature type	protein_coding_gene	FlyBase ID	FBgn0039863
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	100D1-100D1	Sequence location	3R:27,494,957..27,503,703 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG1815 (FBgn0039863). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein kinase C binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Bromodomain; PWWP; Zinc finger, FYVE/PHD-type; Zinc finger, MYND-type; Zinc finger, PHD-finger; Zinc finger, PHD-type; Zinc finger, PHD-type, conserved site; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1641089_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of CG1815. Gene sequence location is 3R:27494957..27503703.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	References Grad et al., 2004, Bioinformatics 20(16): 2738--2750
FB2012_01	Sequence features BKN28842 HFA15310
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 100D1-100D1   Limits computationally determined from genome sequence between P{EP}pygoEP1076 and P{PZ}ttk02667&P{lacW}ttkj6C7
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG1815 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG1815-RA FBtr0085822  NM_170562   7067   1674 CG1815-RB FBtr0085823  NM_170563   5802   1121 CG1815-RC FBtr0085824  NM_143624   5878   1664
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG1815-PA   FBpp0085183   183.1   1674   8.47     NP_733441   AAF57177 CG1815-PB   FBpp0085184   125.0   1121   7.75     NP_733442   AAN14281 CG1815-PC   FBpp0085185   181.9   1664   8.47     NP_651881   AAN14280
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • PWWP (IPR000313) Bromodomain (IPR001487) Zinc finger, PHD-type (IPR001965) Zinc finger, MYND-type (IPR002893) Zinc finger, FYVE/PHD-type (IPR011011) Zinc finger, RING-type (IPR001841) Zinc finger, PHD-type, conserved site (IPR019786) Zinc finger, PHD-finger (IPR019787) Zinc finger, RING/FYVE/PHD-type (IPR013083)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA140829   AA140830   AA202303   AA246487   AE014297 AAF57177   AE014297 AAN14280   AE014297 AAN14281   AI062203   AI063006   AI513098   AI534453   AW941505   AY069824 AAL39969   BI633337   BI637916   BT010115 AAQ22584   BZ748802   CO177772   CO265141   CO267083   CO278823   CO279416   CO282534   CO292867   CO311077   CO319058   CO321303   CO328068   CZ468552   CZ470098   CZ470099   EC060723   EC062091   EC210164   EC210566   EC212524   EC215501   EC221386   EC225190   EC230056   EC235632   EC238960   EC246888   EC250341   EC251605   EV580014
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7KRS9 Q8IMG3 Q8T9C8 Q9V9V5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039863    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039863 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039863 expression level Developmental Stage   Expression Level embryo 00-02hr    2326 embryo 02-04hr    2811 embryo 04-06hr    1532 embryo 06-08hr    1473 embryo 08-10hr    1583 embryo 10-12hr    808 embryo 12-14hr    1161 embryo 14-16hr    1277 embryo 16-18hr    1056 embryo 18-20hr    660 embryo 20-22hr    1573 embryo 22-24hr    1360 larva L1    549 larva L2    404 larva L3 12hr old    352 larva L3 puffstage 1-2    455 larva L3 puffstage 3-6    876 larva L3 puffstage 7-9    1063 white prepupae new    1230 white prepupae 12hr    1026 white prepupae 24hr    1580 pupae 2d postWPP    940 pupae 3d postWPP    570 pupae 4d postWPP    442 adult male 01day    629 adult male 05day    807 adult male 30day    810 adult female 01day    752 adult female 05day    1238 adult female 30day    1288 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2326) embryo 02-04hr  (2811) embryo 04-06hr  (1532) embryo 06-08hr  (1473) embryo 08-10hr  (1583) embryo 10-12hr  (808) embryo 12-14hr  (1161) embryo 14-16hr  (1277) embryo 16-18hr  (1056) embryo 18-20hr  (660) embryo 20-22hr  (1573) embryo 22-24hr  (1360) larva L1  (549) larva L2  (404) larva L3 12hr old  (352) larva L3 puffstage 1-2  (455) larva L3 puffstage 3-6  (876) larva L3 puffstage 7-9  (1063) white prepupae new  (1230) white prepupae 12hr  (1026) white prepupae 24hr  (1580) pupae 2d postWPP  (940) pupae 3d postWPP  (570) pupae 4d postWPP  (442) adult male 01day  (629) adult male 05day  (807) adult male 30day  (810) adult female 01day  (752) adult female 05day  (1238) adult female 30day  (1288) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2326) embryo 02-04hr  (2811) embryo 04-06hr  (1532) embryo 06-08hr  1473 embryo 08-10hr  (1583) embryo 10-12hr    808 embryo 12-14hr    1161 embryo 14-16hr    1277 embryo 16-18hr    1056 embryo 18-20hr    660 embryo 20-22hr  (1573) embryo 22-24hr    1360 larva L1    549 larva L2    404 larva L3 12hr old    352 larva L3 puffstage 1-2    455 larva L3 puffstage 3-6    876 larva L3 puffstage 7-9    1063 white prepupae new    1230 white prepupae 12hr    1026 white prepupae 24hr  (1580) pupae 2d postWPP    940 pupae 3d postWPP    570 pupae 4d postWPP    442 adult male 01day    629 adult male 05day    807 adult male 30day    810 adult female 01day    752 adult female 05day    1238 adult female 30day    1288 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2326 embryo 02-04hr    2811 embryo 04-06hr    1532 embryo 06-08hr    1473 embryo 08-10hr    1583 embryo 10-12hr    808 embryo 12-14hr    1161 embryo 14-16hr    1277 embryo 16-18hr    1056 embryo 18-20hr    660 embryo 20-22hr    1573 embryo 22-24hr    1360 larva L1    549 larva L2    404 larva L3 12hr old    352 larva L3 puffstage 1-2    455 larva L3 puffstage 3-6    876 larva L3 puffstage 7-9    1063 white prepupae new    1230 white prepupae 12hr    1026 white prepupae 24hr    1580 pupae 2d postWPP    940 pupae 3d postWPP    570 pupae 4d postWPP    442 adult male 01day    629 adult male 05day    807 adult male 30day    810 adult female 01day    752 adult female 05day    1238 adult female 30day    1288 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2326 embryo 02-04hr    2811 embryo 04-06hr    1532 embryo 06-08hr    1473 embryo 08-10hr    1583 embryo 10-12hr    808 embryo 12-14hr    1161 embryo 14-16hr    1277 embryo 16-18hr    1056 embryo 18-20hr    660 embryo 20-22hr    1573 embryo 22-24hr    1360 larva L1    549 larva L2    404 larva L3 12hr old    352 larva L3 puffstage 1-2    455 larva L3 puffstage 3-6    876 larva L3 puffstage 7-9    1063 white prepupae new    1230 white prepupae 12hr    1026 white prepupae 24hr    1580 pupae 2d postWPP    940 pupae 3d postWPP    570 pupae 4d postWPP    442 adult male 01day    629 adult male 05day    807 adult male 30day    810 adult female 01day    752 adult female 05day    1238 adult female 30day    1288 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039863 expression level Developmental Stage   Expression Level embryo 00-02hr    2326 embryo 02-04hr    2811 embryo 04-06hr    1532 embryo 06-08hr    1473 embryo 08-10hr    1583 embryo 10-12hr    808 embryo 12-14hr    1161 embryo 14-16hr    1277 embryo 16-18hr    1056 embryo 18-20hr    660 embryo 20-22hr    1573 embryo 22-24hr    1360 larva L1    549 larva L2    404 larva L3 12hr old    352 larva L3 puffstage 1-2    455 larva L3 puffstage 3-6    876 larva L3 puffstage 7-9    1063 white prepupae new    1230 white prepupae 12hr    1026 white prepupae 24hr    1580 pupae 2d postWPP    940 pupae 3d postWPP    570 pupae 4d postWPP    442 adult male 01day    629 adult male 05day    807 adult male 30day    810 adult female 01day    752 adult female 05day    1238 adult female 30day    1288 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2326) embryo 02-04hr  (2811) embryo 04-06hr  (1532) embryo 06-08hr  (1473) embryo 08-10hr  (1583) embryo 10-12hr  (808) embryo 12-14hr  (1161) embryo 14-16hr  (1277) embryo 16-18hr  (1056) embryo 18-20hr  (660) embryo 20-22hr  (1573) embryo 22-24hr  (1360) larva L1  (549) larva L2  (404) larva L3 12hr old  (352) larva L3 puffstage 1-2  (455) larva L3 puffstage 3-6  (876) larva L3 puffstage 7-9  (1063) white prepupae new  (1230) white prepupae 12hr  (1026) white prepupae 24hr  (1580) pupae 2d postWPP  (940) pupae 3d postWPP  (570) pupae 4d postWPP  (442) adult male 01day  (629) adult male 05day  (807) adult male 30day  (810) adult female 01day  (752) adult female 05day  (1238) adult female 30day  (1288) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  2326 embryo 02-04hr  (2811) embryo 04-06hr  1532 embryo 06-08hr  1473 embryo 08-10hr  1583 embryo 10-12hr    808 embryo 12-14hr    1161 embryo 14-16hr    1277 embryo 16-18hr    1056 embryo 18-20hr    660 embryo 20-22hr  1573 embryo 22-24hr    1360 larva L1    549 larva L2    404 larva L3 12hr old    352 larva L3 puffstage 1-2    455 larva L3 puffstage 3-6    876 larva L3 puffstage 7-9    1063 white prepupae new    1230 white prepupae 12hr    1026 white prepupae 24hr  1580 pupae 2d postWPP    940 pupae 3d postWPP    570 pupae 4d postWPP    442 adult male 01day    629 adult male 05day    807 adult male 30day    810 adult female 01day    752 adult female 05day    1238 adult female 30day    1288 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2326 embryo 02-04hr    2811 embryo 04-06hr    1532 embryo 06-08hr    1473 embryo 08-10hr    1583 embryo 10-12hr    808 embryo 12-14hr    1161 embryo 14-16hr    1277 embryo 16-18hr    1056 embryo 18-20hr    660 embryo 20-22hr    1573 embryo 22-24hr    1360 larva L1    549 larva L2    404 larva L3 12hr old    352 larva L3 puffstage 1-2    455 larva L3 puffstage 3-6    876 larva L3 puffstage 7-9    1063 white prepupae new    1230 white prepupae 12hr    1026 white prepupae 24hr    1580 pupae 2d postWPP    940 pupae 3d postWPP    570 pupae 4d postWPP    442 adult male 01day    629 adult male 05day    807 adult male 30day    810 adult female 01day    752 adult female 05day    1238 adult female 30day    1288 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2326 embryo 02-04hr    2811 embryo 04-06hr    1532 embryo 06-08hr    1473 embryo 08-10hr    1583 embryo 10-12hr    808 embryo 12-14hr    1161 embryo 14-16hr    1277 embryo 16-18hr    1056 embryo 18-20hr    660 embryo 20-22hr    1573 embryo 22-24hr    1360 larva L1    549 larva L2    404 larva L3 12hr old    352 larva L3 puffstage 1-2    455 larva L3 puffstage 3-6    876 larva L3 puffstage 7-9    1063 white prepupae new    1230 white prepupae 12hr    1026 white prepupae 24hr    1580 pupae 2d postWPP    940 pupae 3d postWPP    570 pupae 4d postWPP    442 adult male 01day    629 adult male 05day    807 adult male 30day    810 adult female 01day    752 adult female 05day    1238 adult female 30day    1288 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0039863    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0039863 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0039863 expression level Tissue   Expression Level Larval Central Nervous System    485.575 Larval Midgut    118.7 Larval Hindgut    191.5 Larval Malpighian Tubules    165 Larval Fat Body    230.9 Larval Salivary Gland    268 Larval Trachea    278.975 Larval Carcass    192.2 Adult Head    173.5 Adult Eye    176.825 Adult Brain    262.4 Adult Thoracic-Abdominal Ganglion    260.5 Adult Crop    246.1 Adult Midgut    117.2 Adult Hindgut    175.8 Adult Malpighian Tubules    171.2 Adult Fat Body    195.5 Adult Salivary Gland    203.9 Adult Heart    125.5 Adult VirginFemale Spermatheca    253.9 Adult InseminatedFemale Spermatheca    271.5 Adult Ovary    549.8 Adult Testis    68.9 Adult Male Accessory Gland    379.5 Adult Carcass    139.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    485.575 Larval Midgut    118.7 Larval Hindgut    191.5 Larval Malpighian Tubules    165 Larval Fat Body    230.9 Larval Salivary Gland    268 Larval Trachea    278.975 Larval Carcass    192.2 Adult Head    173.5 Adult Eye    176.825 Adult Brain    262.4 Adult Thoracic-Abdominal Ganglion    260.5 Adult Crop    246.1 Adult Midgut    117.2 Adult Hindgut    175.8 Adult Malpighian Tubules    171.2 Adult Fat Body    195.5 Adult Salivary Gland    203.9 Adult Heart    125.5 Adult VirginFemale Spermatheca    253.9 Adult InseminatedFemale Spermatheca    271.5 Adult Ovary  (549.8) Adult Testis    68.9 Adult Male Accessory Gland    379.5 Adult Carcass    139.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    485.575 Larval Midgut    118.7 Larval Hindgut    191.5 Larval Malpighian Tubules    165 Larval Fat Body    230.9 Larval Salivary Gland    268 Larval Trachea    278.975 Larval Carcass    192.2 Adult Head    173.5 Adult Eye    176.825 Adult Brain    262.4 Adult Thoracic-Abdominal Ganglion    260.5 Adult Crop    246.1 Adult Midgut    117.2 Adult Hindgut    175.8 Adult Malpighian Tubules    171.2 Adult Fat Body    195.5 Adult Salivary Gland    203.9 Adult Heart    125.5 Adult VirginFemale Spermatheca    253.9 Adult InseminatedFemale Spermatheca    271.5 Adult Ovary    549.8 Adult Testis    68.9 Adult Male Accessory Gland    379.5 Adult Carcass    139.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    485.575 Larval Midgut    118.7 Larval Hindgut    191.5 Larval Malpighian Tubules    165 Larval Fat Body    230.9 Larval Salivary Gland    268 Larval Trachea    278.975 Larval Carcass    192.2 Adult Head    173.5 Adult Eye    176.825 Adult Brain    262.4 Adult Thoracic-Abdominal Ganglion    260.5 Adult Crop    246.1 Adult Midgut    117.2 Adult Hindgut    175.8 Adult Malpighian Tubules    171.2 Adult Fat Body    195.5 Adult Salivary Gland    203.9 Adult Heart    125.5 Adult VirginFemale Spermatheca    253.9 Adult InseminatedFemale Spermatheca    271.5 Adult Ovary    549.8 Adult Testis    68.9 Adult Male Accessory Gland    379.5 Adult Carcass    139.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0039863 expression level Tissue   Expression Level Larval Central Nervous System    485.575 Larval Midgut    118.7 Larval Hindgut    191.5 Larval Malpighian Tubules    165 Larval Fat Body    230.9 Larval Salivary Gland    268 Larval Trachea    278.975 Larval Carcass    192.2 Adult Head    173.5 Adult Eye    176.825 Adult Brain    262.4 Adult Thoracic-Abdominal Ganglion    260.5 Adult Crop    246.1 Adult Midgut    117.2 Adult Hindgut    175.8 Adult Malpighian Tubules    171.2 Adult Fat Body    195.5 Adult Salivary Gland    203.9 Adult Heart    125.5 Adult VirginFemale Spermatheca    253.9 Adult InseminatedFemale Spermatheca    271.5 Adult Ovary    549.8 Adult Testis    68.9 Adult Male Accessory Gland    379.5 Adult Carcass    139.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    485.575 Larval Midgut    118.7 Larval Hindgut    191.5 Larval Malpighian Tubules    165 Larval Fat Body    230.9 Larval Salivary Gland    268 Larval Trachea    278.975 Larval Carcass    192.2 Adult Head    173.5 Adult Eye    176.825 Adult Brain    262.4 Adult Thoracic-Abdominal Ganglion    260.5 Adult Crop    246.1 Adult Midgut    117.2 Adult Hindgut    175.8 Adult Malpighian Tubules    171.2 Adult Fat Body    195.5 Adult Salivary Gland    203.9 Adult Heart    125.5 Adult VirginFemale Spermatheca    253.9 Adult InseminatedFemale Spermatheca    271.5 Adult Ovary  549.8 Adult Testis    68.9 Adult Male Accessory Gland    379.5 Adult Carcass    139.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    485.575 Larval Midgut    118.7 Larval Hindgut    191.5 Larval Malpighian Tubules    165 Larval Fat Body    230.9 Larval Salivary Gland    268 Larval Trachea    278.975 Larval Carcass    192.2 Adult Head    173.5 Adult Eye    176.825 Adult Brain    262.4 Adult Thoracic-Abdominal Ganglion    260.5 Adult Crop    246.1 Adult Midgut    117.2 Adult Hindgut    175.8 Adult Malpighian Tubules    171.2 Adult Fat Body    195.5 Adult Salivary Gland    203.9 Adult Heart    125.5 Adult VirginFemale Spermatheca    253.9 Adult InseminatedFemale Spermatheca    271.5 Adult Ovary    549.8 Adult Testis    68.9 Adult Male Accessory Gland    379.5 Adult Carcass    139.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    485.575 Larval Midgut    118.7 Larval Hindgut    191.5 Larval Malpighian Tubules    165 Larval Fat Body    230.9 Larval Salivary Gland    268 Larval Trachea    278.975 Larval Carcass    192.2 Adult Head    173.5 Adult Eye    176.825 Adult Brain    262.4 Adult Thoracic-Abdominal Ganglion    260.5 Adult Crop    246.1 Adult Midgut    117.2 Adult Hindgut    175.8 Adult Malpighian Tubules    171.2 Adult Fat Body    195.5 Adult Salivary Gland    203.9 Adult Heart    125.5 Adult VirginFemale Spermatheca    253.9 Adult InseminatedFemale Spermatheca    271.5 Adult Ovary    549.8 Adult Testis    68.9 Adult Male Accessory Gland    379.5 Adult Carcass    139.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    173.5   NA  Eye    176.825   NA  Brain    262.4   485.575  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    260.5   NA  Crop    246.1   118.7  Midgut    117.2   191.5  Hindgut    175.8   165  Malpighian Tubules    171.2   230.9  Fat Body    195.5   268  Salivary Gland    203.9   NA  Heart    125.5   278.975  Trachea    NA   NA  VirginFemale Spermatheca    253.9   NA  InseminatedFemale Spermatheca    271.5   NA  Ovary    549.8   NA  Testis    68.9   NA  Male Accessory Gland    379.5   192.2  Carcass    139.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_01
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039863 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1815-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG1815 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG1815GD9521 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG1815 Class Mutagen Stocks Known lesion CG1815c03273 piggyBac transposase 1 -- CG1815EY01163 P-element activity 1 -- CG1815MI01646 1 -- CG1815c05558 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG1815 Class Mutagen Stocks Known lesion CG1815GD9521 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG1815KK108842 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9521} NA P{KK108842} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG1815EY01163 NA miscellaneous insertions Mi{MIC}CG1815MI01646 NA PBac{PB}CG1815c03273 NA PBac{PB}CG1815c05558 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
protein kinase C binding inferred from sequence or structural similarity with EMBL:U48251 (FlyBase, 1992-) zinc ion binding inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001965, InterPro:IPR002893 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG1815 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68573 DroID - A comprehensive database of gene and protein interactions. • FBgn0039863 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43730
Orthologs
Genome-wide drosophilid orthologs	Dana\GF22978 Dere\GG11823 Dgri\GH18646 Dmoj\GI23125 Dper\GL23991 Dpse\GA26472 Dsec\GM16440 Dsim\GD21594 Dvir\GJ23097 Dwil\GK12113 Dyak\GE10956
Curated drosophilid orthologs	Dpse\GA14818
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL009893-PA Aedes aegypti (mosquito) XP_396333.2 Apis mellifera (honey bee) BGIBMGA003378-PA Bombyx mori (silk worm) ENSBTAP00000004258 Bos taurus (bovine) ENSCAFP00000015830 Canis familiaris (dog) ENSCINP00000024448 Ciona intestinalis (sea squirt) CPIJ007517 Culex pipens (mosquito) ENSCPOP00000012018 Cavia porcellus (guinea pig) ENSCSAVP00000010875 Ciona savignyi (sedentary tunicate) 219104 Capitella spl (polychaete worm) 324633 Daphnia pulex (daphnia) ENSDARP00000040234 Danio rerio (zebra fish) ENSGACP00000013240 Gymnopilus aculeatus (mushroom) ENSGALP00000007220 Gallus gallus (chicken) ENSP00000262975 Homo sapiens (human) ISCW009345-PA Ixodes scapularis (deer tick) ENSMODP00000020299 Monodelphis domestica (gray opossum) ENSMUSP00000104892 Mus musculus (house mouse) ENSOANP00000009755 Ornithorynchus anatinus (platypus) ENSORLP00000015086 Oryzias latipes (japanese killifish) PHUM005126-PA Pediculus humanus (human body louse) ENSPPYP00000012404 Pongo pygmaeus (orangutan) ENSPTRP00000023370 Pan troglodytes (chimpanzee) ENSRNOP00000025932 Rattus norvegicus (norway rat) Smp_170390 Schistosoma mansoni (trematode parasite) XP_001179865.1 Strongylocentrotus purpuratus (purple sea urchin) XP_967933.2 Tribolium castaneum (red flour beetle) ENSTNIP00000010106 Tetraodon nigroviridis (green spotted pufferfish) ENSTNIP00000015574 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000014214 Takifugu rubripes (pufferfish Takifugu) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13408 LH17232 ISCW009345 FBgn0228786 FBgn0214124 FBgn0210199 FBgn0193019 FBgn0171355 JGI_V11_324633 FBgn0247846 FBgn0161581 FBgn0145852 FBgn0126113 FBgn0104118 FBgn0099972 CPIJ007517 BGIBMGA003378 GB12499 AGAP002983 AAEL009893 PB21132 PHUM075890 GLEAN_10913
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	35948 y1 w*; Mi{MIC}CG1815MI01646 15328 y1 w67c23; P{EPgy2}CG1815EY01163
Harvard	- PBac{PB}CG1815c03273
VDRC	v107321 P{KK108842}VIE-260B v40132 w1118; P{GD9521}v40132/CyO
Genomic Clones ( 2 )
	BACR16C04 BACR48C22 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 34 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH01331 SD07276
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH02411 LD05532 SD27406
Other clones	15534 21026 31465 38213 44916 69954 72421 72878 100690 164473 174288 175106 214247.30 CK01.67B.D10 CK00500 Dmel_dig_013799_0682_2582 EK054245 EK131748 EK134256 EK141633 EK148701 EK160657 EK201121 EK223315 EK276126 EK290654 EP08522 LD02460 SD20070
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039863 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43730
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143624 NM_170562 NM_170563 RefSeq (Proteins) • NP_651881 NP_733441 NP_733442 DDBJ / EMBL / GenBank • AA202303 AAF57177 AAL39969 AAN14280 AAN14281 AAQ22584 AI062203 AI513098 AI534453 AW941505 AY069824 BT010115 BZ748802 CZ468552 CZ470098 CZ470099 Entrez Gene - A searchable database of RefSeq genes. • 43730 UniProtKB/TrEMBL • Q7KRS9 Q8IMG3 Q8T9C8 Q9V9V5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • PWWP (IPR000313) Bromodomain (IPR001487) Zinc finger, PHD-type (IPR001965) Zinc finger, MYND-type (IPR002893) Zinc finger, FYVE/PHD-type (IPR011011) Zinc finger, RING-type (IPR001841) Zinc finger, PHD-type, conserved site (IPR019786) Zinc finger, PHD-finger (IPR019787) Zinc finger, RING/FYVE/PHD-type (IPR013083)
Linkouts
	BioGRID - A database of protein and genetic interactions • 68573 DroID - A comprehensive database of gene and protein interactions. • FBgn0039863 DRSC - Results from RNAi screens. • FBgn0039863 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039863 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1815-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039863 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43730 InParanoid A subset of ortholog calls from InParanoid. • AAEL009893-PA Aedes aegypti (mosquito) XP_396333.2 Apis mellifera (honey bee) BGIBMGA003378-PA Bombyx mori (silk worm) ENSBTAP00000004258 Bos taurus (bovine) ENSCAFP00000015830 Canis familiaris (dog) ENSCINP00000024448 Ciona intestinalis (sea squirt) CPIJ007517 Culex pipens (mosquito) ENSCPOP00000012018 Cavia porcellus (guinea pig) ENSCSAVP00000010875 Ciona savignyi (sedentary tunicate) 219104 Capitella spl (polychaete worm) 324633 Daphnia pulex (daphnia) ENSDARP00000040234 Danio rerio (zebra fish) ENSGACP00000013240 Gymnopilus aculeatus (mushroom) ENSGALP00000007220 Gallus gallus (chicken) ENSP00000262975 Homo sapiens (human) ISCW009345-PA Ixodes scapularis (deer tick) ENSMODP00000020299 Monodelphis domestica (gray opossum) ENSMUSP00000104892 Mus musculus (house mouse) ENSOANP00000009755 Ornithorynchus anatinus (platypus) ENSORLP00000015086 Oryzias latipes (japanese killifish) PHUM005126-PA Pediculus humanus (human body louse) ENSPPYP00000012404 Pongo pygmaeus (orangutan) ENSPTRP00000023370 Pan troglodytes (chimpanzee) ENSRNOP00000025932 Rattus norvegicus (norway rat) Smp_170390 Schistosoma mansoni (trematode parasite) XP_001179865.1 Strongylocentrotus purpuratus (purple sea urchin) XP_967933.2 Tribolium castaneum (red flour beetle) ENSTNIP00000010106 Tetraodon nigroviridis (green spotted pufferfish) ENSTNIP00000015574 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000014214 Takifugu rubripes (pufferfish Takifugu) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43730 modMine - Data generated by the modENCODE project. • FBgn0039863 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13408 LH17232 ISCW009345 FBgn0228786 FBgn0214124 FBgn0210199 FBgn0193019 FBgn0171355 JGI_V11_324633 FBgn0247846 FBgn0161581 FBgn0145852 FBgn0126113 FBgn0104118 FBgn0099972 CPIJ007517 BGIBMGA003378 GB12499 AGAP002983 AAEL009893 PB21132 PHUM075890 GLEAN_10913
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG1815 (Pilot et al., 2006, Bienz, 2006, Keleman et al., 2009.8.5, Grad et al., 2004)
Name Synonym
Secondary FlyBase IDs
References ( 20 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Pilot et al., 2006, Development 133(4): 711--723 Developmental control of nuclear morphogenesis and anchoring by charleston, identified in a functional genomic screen of Drosophila cellularisation. [FBrf0190315] Grad et al., 2004, Bioinformatics 20(16): 2738--2750 Prediction of similarly acting cis-regulatory modules by subsequence profiling and comparative genomics in Drosophila melanogaster and D.pseudoobscura. [FBrf0183757] Orian et al., 2003, Genes Dev. 17(9): 1101--1114 Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. [FBrf0158942] Brody et al., 2002, Mech. Dev. 113(1): 41--59 Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. [FBrf0147137] Veraksa et al., 2002, genesis 33(2): 67--76 DEAF-1 function is essential for the early embryonic development of Drosophila. [FBrf0151504]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Review	Bienz, 2006, Trends Biochem. Sci. 31(1): 35--40 [FBrf0199098]
Personal communication to FlyBase	Bellen, 2011.5.24, set932.xml set932.xml [FBrf0213718] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]