Gene model reviewed during 5.55
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
Gene model reviewed during 6.03
Component of the 4EHP-GYF2 complex, composed of at least eIF4EHP and Gyf (PubMed:31114929). Interacts (via N-terminus) with eIF4EHP; interaction is required for eIF4EHP-mediated translational repression and mRNA decay (PubMed:31114929). Interacts (via me31B binding motif) with the decapping activator DDX6/ME31B (via RecA-like domain 2), and also interacts (via GYF domain) with the decapping effector protein Patr-1 (PubMed:31114929, PubMed:31439631). Also interacts with other decapping effector proteins, such as Edc3 and Ge-1 (PubMed:31114929). Interacts with CCR4-NOT deadenylase complex members Not1, Not3, Pop2 and twin, and other components of the deadenylation complexes such as Rga, PAN2 and PAN3 (PubMed:31114929).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Gyf using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Gyf in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Gyf CG11148
Named based on orthology to mammalian GIGYF1 and GIGYF2