FlyBase Gene Report: Dmel\Sox102F

General Information

Symbol

Dmel\Sox102F

Species

D. melanogaster

Name

Sox102F

Annotation Symbol

CG11153

Feature Type

protein_coding_gene

FlyBase ID

FBgn0039938

Gene Model Status

Current

Stock Availability

13 publicly available

Gene Snapshot

Sox102F (Sox102F) encodes a transcription factor in the Sox gene family that regulates the Wnt signaling pathway. Its roles include heart development and cardiac function, and wing vein development and patterning. [Date last reviewed: 2019-03-14]

Other Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

SoxD

Key Links

Genomic Location

Cytogenetic map

Sequence location

4:800,436..834,393 [-]

Recombination map

4-0

RefSeq locus

NC_004353 REGION:800436..834393

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

NCBI

UCSC

Ensembl

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (6 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables DNA-binding transcription factor activity, RNA polymerase II-specific

inferred from biological aspect of ancestor with PANTHER:PTN002909527

(assigned by GO_Central )

(Gaudet et al., 2011)

enables RNA polymerase II cis-regulatory region sequence-specific DNA binding

inferred from biological aspect of ancestor with PANTHER:PTN002909527

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (3 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in positive regulation of heart contraction

inferred from mutant phenotype

(Li et al., 2013)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in cell fate commitment

inferred from biological aspect of ancestor with PANTHER:PTN000030844

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in regulation of transcription by RNA polymerase II

inferred from biological aspect of ancestor with PANTHER:PTN002909527

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

located_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN002909527

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

HIGH MOBILITY GROUP BOX TRANSCRIPTION FACTORS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

HIGH MOBILITY GROUP BOX TRANSCRIPTION FACTORS -: The High mobility group box (HMGB) transcription factors are sequence-specific DNA binding proteins that regulate transcription. The HMGB proteins have a characteristic L-shaped HMGB domain of about 80 amino acid residues, which binds the DNA minor groove and induce DNA bending. The HMGB domains are found in one or more copies and are involved in the regulation of DNA-dependent processes such as transcription, replication and chromatin remodeling. (Adapted from FBrf0194706, FBrf0108466, PMID:24086078 and PMID:23153957).

Summary (Interactive Fly)

(common alternative name: SoxD) HMG-domain protein - SOX-domain transcription factor - optic lobe - olfactory perception - neuromuscular junction - axon guidance, adult courtship behavior - wing - heart

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Sox102F for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Sox102F-RA

FBtr0089252

NM_166792

2767

580

Sox102F-RB

FBtr0100600

NM_001014695

3804

618

Sox102F-RC

FBtr0334488

NM_001272144

2840

580

Sox102F-RD

FBtr0334489

NM_001272145

2902

580

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

Sox102F-PA

FBpp0088312

62.8

580

7.84

NP_726612

AAF59408

Sox102F-PB

FBpp0100057

67.2

618

7.72

NP_001014695

AAX52518

Sox102F-PC

FBpp0306556

62.8

580

7.84

NP_001259073

AGB96563

Sox102F-PD

FBpp0306557

62.8

580

7.84

NP_001259074

AGB96564

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

580 aa isoforms: Sox102F-PA, Sox102F-PC, Sox102F-PD

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sox102F using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 16 -- 17

neuron of embryonic/larval brain

(Cremazy et al., 2001)

neuron of ventral nerve cord

(Cremazy et al., 2001)

third instar larval stage

embryonic/larval brain | restricted

(Cremazy et al., 2001)

embryonic stage 13 -- 16

embryonic brain

(Fisher et al., 2012)

mushroom body primordium

Comment: reported as embryonic central brain mushroom body

(Fisher et al., 2012)

ventral nerve cord

(Fisher et al., 2012)

Additional Descriptive Data

Sox102F is first expressed at embryonic stages 17/17, in the brain and in a subset of neuronal cells in the ventral nerve cord. In third instar larvae, Sox102F is expressed at the interface of the central brain and optic lobes. Sox102F transcript is undetectable in imaginal discs.

(Cremazy et al., 2001)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

T neuron T4

(Schilling et al., 2019)

T neuron T5

(Schilling et al., 2019)

adult stage

T neuron T4

(Schilling et al., 2019)

T neuron T5

(Schilling et al., 2019)

Additional Descriptive Data

Sox102F is expressed in all T4/T5 neuron subtypes, but not in their progenitors or in C/T neurons.

(Schilling et al., 2019)

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Sox102F in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Sox102F

View exonic expression by tissue for Dmel\Sox102F

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0039938

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0039938

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG11153-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG11153

Flygut - An atlas of the Drosophila adult midgut

FBgn0039938

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\Sox102F

Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 4 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 11 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Sox102F

Transgenic constructs containing regulatory region of Sox102F

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation

Inferred from location

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Bx-MS1096

Sox102F^{UAS.ORF.GW.Tag:HA}

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Sox102F^GD4589

viable, with Scer\GAL4^Mef2.PR

Sox102F^GD4589

viable, with Scer\GAL4^pnr-MD237

Sox102F^GD4589

viable, with Scer\GAL4^tin.CΔ4

Sox102F^GD4589

Other Phenotypes

Allele

abnormal courtship behavior, with Scer\GAL4^insc.PU

Sox102F^JF02118

abnormal locomotor behavior | adult stage, with Scer\GAL4^Toll-6-D42

Sox102F^JF02118

abnormal locomotor behavior | third instar larval stage, with Scer\GAL4^Toll-6-D42

Sox102F^JF02118

abnormal neuroanatomy | adult stage, with Scer\GAL4^insc.PU

Sox102F^JF02118

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^ppk.PU

Sox102F^JF02118

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^Toll-6-D42

Sox102F^JF02118

abnormal smell perception | third instar larval stage, with Scer\GAL4^Tab2-201Y

Sox102F^JF02118

visible, with Scer\GAL4^Bx-MS1096-KE

Sox102F^HJF

visible, with Scer\GAL4^ey.PH

Sox102F^HJF

visible, with Scer\GAL4^GMR.PF

Sox102F^HJF

visible, with Scer\GAL4^sd-SG29.1

Sox102F^JF02118

Phenotype manifest in

Allele

adult brain, with Scer\GAL4^insc.PU

Sox102F^JF02118

adult heart, with Scer\GAL4^how-24B

Sox102F^JF02118

dendritic arborizing neuron | third instar larval stage, with Scer\GAL4^ppk.PU

Sox102F^JF02118

dendritic tree | third instar larval stage, with Scer\GAL4^ppk.PU

Sox102F^JF02118

eye, with Scer\GAL4^ey.PH

Sox102F^HJF

eye, with Scer\GAL4^GMR.PF

Sox102F^HJF

microchaeta, with Scer\GAL4^pnr.PU

Sox102F^JF02118

myofibril, with Scer\GAL4^how-24B

Sox102F^JF02118

NMJ bouton | third instar larval stage, with Scer\GAL4^Toll-6-D42

Sox102F^JF02118

wing, with Scer\GAL4^Bx-MS1096-KE

Sox102F^HJF

wing, with Scer\GAL4^sd-SG29.1

Sox102F^JF02118

wing vein L2, with Scer\GAL4^sd-SG29.1

Sox102F^JF02118

wing vein L3, with Scer\GAL4^sd-SG29.1

Sox102F^JF02118

wing vein L3 | ectopic, with Scer\GAL4^sd-SG29.1

Sox102F^JF02118

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (23)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\SOX5

11 of 15

Yes

Hsap\SOX6

9 of 15

Yes

Hsap\SOX13

7 of 15

Yes

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

1 of 15

Yes

Hsap\MIR6073

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (21)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Sox5

11 of 15

Yes

Mmus\Sox6

10 of 15

Yes

Mmus\Sox13

7 of 15

Yes

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Rattus norvegicus (Norway rat) (14)

Rnor\Sox5

9 of 13

Yes

Rnor\Sox6

7 of 13

Yes

Rnor\Sox13

7 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

Xenopus tropicalis (Western clawed frog) (15)

Xtro\sox5

9 of 12

Yes

Xtro\sox6

9 of 12

Yes

Xtro\sox13

7 of 12

Yes

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Danio rerio (Zebrafish) (26)

Drer\sox6

8 of 15

Yes

Drer\sox5

7 of 15

Yes

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

2 of 15

Yes

2 of 15

2 of 15

2 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Caenorhabditis elegans (Nematode, roundworm) (3)

Cele\egl-13

8 of 15

Yes

Cele\sox-3

1 of 15

Cele\sox-4

1 of 15

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\ROX1

2 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (3)

Spom\matmc_1

2 of 12

Yes

Spom\matmc_2

1 of 12

Spom\ste11

1 of 12

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091906Q5 )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA10800

Drosophila persimilis

Dper\GL15612

Drosophila willistoni

Dwil\GK13587

Drosophila virilis

Dvir\GJ16077

Drosophila mojavensis

Dmoj\GI14086

Drosophila grimshawi

Dgri\GH24007

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915044Q )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17008228

Glossina morsitans

Tsetse fly

Gmor\GMOY001535

Mayetiola destructor

Hessian fly

Mdes\Mdes009814

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL005518

Anopheles darlingi

American malaria mosquito

Adar\ADAC001559

Anopheles gambiae

Malaria mosquito

Agam\AGAP000066

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ006395

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W07IN )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA009439

Danaus plexippus

Monarch butterfly

Dple\DPOGS213248-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL008081

Apis florea

Little honeybee

Aflo\3511762548

Apis mellifera

Western honey bee

Amel\GB41464

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP14742

Bombus terrestris

Buff-tailed bumblebee

Bter\15214503

Linepithema humile

Argentine ant

Lhum\LH13769

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:001364

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG015884

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_00723

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_01092

Tribolium castaneum

Red flour beetle

Tcas\GLEAN_07419

Pediculus humanus

Human body louse

Phum\PHUM095890

Rhodnius prolixus

Kissing bug

Rpro\RPRC001038

Cimex lectularius

Bed bug

Clec\CLEC008310

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI008847

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_04230

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X07DV )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR012049

Ixodes scapularis

Black-legged tick

Isca\ISCW023359

Stegodyphus mimosarum

African social velvet spider

Smim\KFM66970.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur24g01340

Tetranychus urticae

Two-spotted spider mite

Turt\tetur15g02270

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_37711

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_37708

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )

No non-Arthropod Metazoa orthologies identified

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (7)

Gene Symbol

Score

Source

Alignment

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Allele

Disease

Evidence

References

Sox102F^JF02118

model of heart disease

CEA

(Li et al., 2013)

model of Alzheimer's disease

CEA

(Li et al., 2017)

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

SOX5; SRY-box transcription factor 5

11 of 15

604975

LAMB-SHAFFER SYNDROME; LAMSHF

SOX6; SRY-box transcription factor 6

9 of 15

607257

TOLCHIN-LE CAIGNEC SYNDROME; TOLCAS

SOX13; SRY-box transcription factor 13

7 of 15

604748

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Sox102F - CtBP

two hybrid array

(Shokri et al., 2019)

Sox102F - Hr78

two hybrid array

(Shokri et al., 2019)

Sox102F - Irbp18

two hybrid array

(Shokri et al., 2019)

Sox102F - Rel

two hybrid array

(Shokri et al., 2019)

Sox102F - croc

two hybrid array

(Shokri et al., 2019)

Sox102F - drm

two hybrid array

(Shokri et al., 2019)

Sox102F - p53

two hybrid array

(Shokri et al., 2019)

Sox102F - pdm2

two hybrid array

(Shokri et al., 2019)

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

68668

DroID - A comprehensive database of gene and protein interactions.

FBgn0039938

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

43844

MIST (protein-protein) - An integrated Molecular Interaction Database

Sox102F

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Deactivation of the beta-catenin transactivating complex

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

4-0

Cytogenetic map

102E1-102E3

Sequence location

4:800,436..834,393 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

102E1-102E3

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

4-0

(FlyBase, 2016)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (13)

Bloomington

56533

w^*; Mi{Hto-WP}Sox102F^HJF

32729

y¹; Mi{MIC}Sox102F^MI01054

60748

y¹; Mi{MIC}Sox102F^MI01537

26220

y¹ v¹; P{TRiP.JF02118}attP2

42288

w¹¹¹⁸; PBac{Sox102F-GFP.FPTB}VK00033

91796

y¹ w^*; P{UAS-Sox102F.S}su(Hw)attP1

79992

y¹ sc^* v¹ sev²¹; P{TOE.GS02765}attP40

65133

y¹ sc^* v¹ sev²¹; P{TRiP.HMC05985}attP40

FlyORF

F001902

M{UAS-Sox102F.ORF.3xHA.GW}ZH-86Fb

VDRC

v330016

P{VSH330016}attP40

v19022

w¹¹¹⁸; P{GD4589}v19022

v341318

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD00370}attP40/CyO-GFP

More stocks available...

Genomic Clones (19)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (25)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD16247

Other clones

FI18025

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0039938

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0039938

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

43844

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Schilling et al., 2019)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: Sox102F SoxD

(FlyBase, 1996-)

Source for identity of: Sox102F CG11153

(McKimmie et al., 2001, Overton, 2001.9.6)

Source for database merge of

Additional comments

Other Comments

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 60 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

43844

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0039938

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0039938

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG11153

Flygut - An atlas of the Drosophila adult midgut

FBgn0039938

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

43844

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC007419

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG11153

modMine - A data warehouse for the modENCODE project

FBgn0039938

Linkouts

BioGRID - A database of protein and genetic interactions.

68668

DroID - A comprehensive database of gene and protein interactions.

FBgn0039938

DRSC - Results frm RNAi screens

FBgn0039938

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0039938

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG11153-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0039938

FlyMine - An integrated database for Drosophila genomics

FBgn0039938

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

43844

MIST (protein-protein) - An integrated Molecular Interaction Database

Sox102F

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Deactivation of the beta-catenin transactivating complex

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

CG11153

(Meadows, 2017.1.11, Hosono et al., 2015, Perkins et al., 2009, Perkins et al., 2009.3.31, Wang et al., 2002, Cremazy et al., 2001)

SOX102D

(Bowles et al., 2000)

SOX102F

(Yang et al., 2020)

SOXD

(Bowles et al., 2000)

Sox D

(Cremazy et al., 2001)

Sox102D

SoxD

(Contreras et al., 2018)

Name Synonyms

Sox102F

Secondary FlyBase IDs

FBgn0043567

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (56)

The following external sites may use different assemblies or annotations than FlyBase.

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