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Gene Dmel\CG17082

General Information
Symbol	Dmel\CG17082	Species	D. melanogaster
Name		Annotation symbol	CG17082
Feature type	protein_coding_gene	FlyBase ID	FBgn0039994
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	41C1-41C1	Sequence location	2R:631,853..645,553 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG17082 (FBgn0039994). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: signal transduction. 2 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Rho GTPase activation protein; Rho GTPase-activating protein domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1625804_s_at completely aligns to an exonic region common to each of the 6 FlyBase-annotated transcript isoforms of CG17082. Gene sequence location is 2R:631853..645553.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 41C1-41C1
Experimentally Determined Cytological Location
Cytogenetic map Notes References 41C1-41C6   h46   (Drosophila Heterochromatin Genome Project, 2004)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG17082 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Annotated transcripts do not represent all supported alternative splices within 5' UTR. Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG17082-RA FBtr0111287  NM_001042989   2204   629 CG17082-RB FBtr0111288  NM_001042993   2329   629 CG17082-RD FBtr0111285  NM_001042992   2091   629 CG17082-RG FBtr0302385  NM_001042990   2098   629 CG17082-RH FBtr0334993  NM_001042991   2015   582
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG17082-PA   FBpp0110498   71.7   629   7.34     NP_001036454   EAA45992 CG17082-PB   FBpp0110554   71.7   629   7.34     NP_001036458   EAA45993 CG17082-PD   FBpp0110582   71.7   629   7.34     NP_001036457   EAA45990 CG17082-PG   FBpp0291580   71.7   629   7.34     NP_001036455   EAA45991 CG17082-PH   FBpp0307003   65.9   582   9.42     NP_001036456   EAA45994
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Rho GTPase-activating protein domain (IPR000198) Rho GTPase activation protein (IPR008936)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201236   AA201744   AA264594   AA390638   AA441024   AA536345   AA948923   AA990731   AABU01002769 EAA45990   AABU01002769 EAA45991   AABU01002769 EAA45992   AABU01002769 EAA45993   AABU01002769 EAA45994   AABU01002769 EAA45995   AI109711   AY069334   AY119651   BG635702   BI162430   BI164963   BI169087   BI171092   BI173592   BI212951   BI214545   BI215435   BI216624   BI227672   BI228062   BI228209   BI228681   BI228974   BI231108   BI231283   BI232447   BI235507   BI236582   BI236610   BI237259   BI237311   BI238238   BI238697   BI239057   BI241353   BI356777   BI362389   BI364444   BI364570   BI366957   BI367740   BI368144   BI368754   BI374865   BI374878   BI375009   BI375957   BI376051   BI482175   BI483728   BI484107   BI484189   BI485537   BI485888   BI486090   BI578309   BI579195   BI638985   BI639739   BP553587   BP553588   BT099908   BT149890   CO178016   CO187664   CO188368   CO264113   CO279627   CO286964   CO288327   CO290728   CO294253   CO294999   CO303851   CO304250   CO308294   CO317086   CO322239   CO327121   CO328427   CO336692   CO336711   CO339711   CO345105   CO345229   AE013599 EAA45990   AE013599 EAA45991   AE013599 EAA45992   AE013599 EAA45993   AE013599 EAA45994   EC058663   EC058931   EC064058   EC077665   EC081636   EC083660   EC086887   EC205611   EC205738   EC207435   EC212178   EC217813   EC223498   EC241624   EC241907   EC247486   EC255198   EC257565   EC267832   EV583050   EV589377   GH941531   GH943427   GH946172   GH948296   GH949834   GH950183   GH952147   GH953716   GH953983   GH955597   GH960930   GH961792   GH962546   GH965390   GH968517   GH969400   GH971332   GH975965   GH977742   GH979719   GH981482   GH982862   GH983900
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8T0G4 Q0E9Q3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | faint & ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    372.35 Larval Midgut    221.1 Larval Hindgut    291.2 Larval Malpighian Tubules    404.3 Larval Fat Body    450.9 Larval Salivary Gland    425.3 Larval Trachea    346.25 Larval Carcass    286.175 Adult Head    226.5 Adult Eye    257.525 Adult Brain    409.8 Adult Thoracic-Abdominal Ganglion    335.3 Adult Crop    359.1 Adult Midgut    189.4 Adult Hindgut    273.4 Adult Malpighian Tubules    386.3 Adult Fat Body    209.9 Adult Salivary Gland    464.6 Adult Heart    201.15 Adult VirginFemale Spermatheca    289 Adult InseminatedFemale Spermatheca    273.8 Adult Ovary    865.9 Adult Testis    55.6 Adult Male Accessory Gland    208.5 Adult Carcass    186.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    372.35 Larval Midgut    221.1 Larval Hindgut    291.2 Larval Malpighian Tubules    404.3 Larval Fat Body    450.9 Larval Salivary Gland    425.3 Larval Trachea    346.25 Larval Carcass    286.175 Adult Head    226.5 Adult Eye    257.525 Adult Brain    409.8 Adult Thoracic-Abdominal Ganglion    335.3 Adult Crop    359.1 Adult Midgut    189.4 Adult Hindgut    273.4 Adult Malpighian Tubules    386.3 Adult Fat Body    209.9 Adult Salivary Gland    464.6 Adult Heart    201.15 Adult VirginFemale Spermatheca    289 Adult InseminatedFemale Spermatheca    273.8 Adult Ovary  (865.9) Adult Testis    55.6 Adult Male Accessory Gland    208.5 Adult Carcass    186.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    372.35 Larval Midgut    221.1 Larval Hindgut    291.2 Larval Malpighian Tubules    404.3 Larval Fat Body    450.9 Larval Salivary Gland    425.3 Larval Trachea    346.25 Larval Carcass    286.175 Adult Head    226.5 Adult Eye    257.525 Adult Brain    409.8 Adult Thoracic-Abdominal Ganglion    335.3 Adult Crop    359.1 Adult Midgut    189.4 Adult Hindgut    273.4 Adult Malpighian Tubules    386.3 Adult Fat Body    209.9 Adult Salivary Gland    464.6 Adult Heart    201.15 Adult VirginFemale Spermatheca    289 Adult InseminatedFemale Spermatheca    273.8 Adult Ovary    865.9 Adult Testis    55.6 Adult Male Accessory Gland    208.5 Adult Carcass    186.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    372.35 Larval Midgut    221.1 Larval Hindgut    291.2 Larval Malpighian Tubules    404.3 Larval Fat Body    450.9 Larval Salivary Gland    425.3 Larval Trachea    346.25 Larval Carcass    286.175 Adult Head    226.5 Adult Eye    257.525 Adult Brain    409.8 Adult Thoracic-Abdominal Ganglion    335.3 Adult Crop    359.1 Adult Midgut    189.4 Adult Hindgut    273.4 Adult Malpighian Tubules    386.3 Adult Fat Body    209.9 Adult Salivary Gland    464.6 Adult Heart    201.15 Adult VirginFemale Spermatheca    289 Adult InseminatedFemale Spermatheca    273.8 Adult Ovary    865.9 Adult Testis    55.6 Adult Male Accessory Gland    208.5 Adult Carcass    186.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    372.35 Larval Midgut    221.1 Larval Hindgut    291.2 Larval Malpighian Tubules    404.3 Larval Fat Body    450.9 Larval Salivary Gland    425.3 Larval Trachea    346.25 Larval Carcass    286.175 Adult Head    226.5 Adult Eye    257.525 Adult Brain    409.8 Adult Thoracic-Abdominal Ganglion    335.3 Adult Crop    359.1 Adult Midgut    189.4 Adult Hindgut    273.4 Adult Malpighian Tubules    386.3 Adult Fat Body    209.9 Adult Salivary Gland    464.6 Adult Heart    201.15 Adult VirginFemale Spermatheca    289 Adult InseminatedFemale Spermatheca    273.8 Adult Ovary    865.9 Adult Testis    55.6 Adult Male Accessory Gland    208.5 Adult Carcass    186.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    372.35 Larval Midgut    221.1 Larval Hindgut    291.2 Larval Malpighian Tubules    404.3 Larval Fat Body    450.9 Larval Salivary Gland    425.3 Larval Trachea    346.25 Larval Carcass    286.175 Adult Head    226.5 Adult Eye    257.525 Adult Brain    409.8 Adult Thoracic-Abdominal Ganglion    335.3 Adult Crop    359.1 Adult Midgut    189.4 Adult Hindgut    273.4 Adult Malpighian Tubules    386.3 Adult Fat Body    209.9 Adult Salivary Gland    464.6 Adult Heart    201.15 Adult VirginFemale Spermatheca    289 Adult InseminatedFemale Spermatheca    273.8 Adult Ovary  (865.9) Adult Testis    55.6 Adult Male Accessory Gland    208.5 Adult Carcass    186.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    372.35 Larval Midgut    221.1 Larval Hindgut    291.2 Larval Malpighian Tubules    404.3 Larval Fat Body    450.9 Larval Salivary Gland    425.3 Larval Trachea    346.25 Larval Carcass    286.175 Adult Head    226.5 Adult Eye    257.525 Adult Brain    409.8 Adult Thoracic-Abdominal Ganglion    335.3 Adult Crop    359.1 Adult Midgut    189.4 Adult Hindgut    273.4 Adult Malpighian Tubules    386.3 Adult Fat Body    209.9 Adult Salivary Gland    464.6 Adult Heart    201.15 Adult VirginFemale Spermatheca    289 Adult InseminatedFemale Spermatheca    273.8 Adult Ovary    865.9 Adult Testis    55.6 Adult Male Accessory Gland    208.5 Adult Carcass    186.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    372.35 Larval Midgut    221.1 Larval Hindgut    291.2 Larval Malpighian Tubules    404.3 Larval Fat Body    450.9 Larval Salivary Gland    425.3 Larval Trachea    346.25 Larval Carcass    286.175 Adult Head    226.5 Adult Eye    257.525 Adult Brain    409.8 Adult Thoracic-Abdominal Ganglion    335.3 Adult Crop    359.1 Adult Midgut    189.4 Adult Hindgut    273.4 Adult Malpighian Tubules    386.3 Adult Fat Body    209.9 Adult Salivary Gland    464.6 Adult Heart    201.15 Adult VirginFemale Spermatheca    289 Adult InseminatedFemale Spermatheca    273.8 Adult Ovary    865.9 Adult Testis    55.6 Adult Male Accessory Gland    208.5 Adult Carcass    186.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    226.5   NA  Eye    257.525   NA  Brain    409.8   372.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    335.3   NA  Crop    359.1   221.1  Midgut    189.4   291.2  Hindgut    273.4   404.3  Malpighian Tubules    386.3   450.9  Fat Body    209.9   425.3  Salivary Gland    464.6   NA  Heart    201.15   346.25  Trachea    NA   NA  VirginFemale Spermatheca    289   NA  InseminatedFemale Spermatheca    273.8   NA  Ovary    865.9   NA  Testis    55.6   NA  Male Accessory Gland    208.5   286.175  Carcass    186.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    33 central nervous system, pupae P8    39 head, virgin 1-day female    19 head, virgin 4-day female    21 head, virgin 20-day female    21 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    18 head, mated 1-day male    24 head, mated 4-day male    29 head, mated 20-day male    32 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    46 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    15 digestive system, 4-day adult    14 digestive system, 20-day adult    12 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    28 carcass, larvae L3 wandering    25 carcass, 1-day adult    12 carcass, 4-day adult    18 carcass, 20-day adult    17 ovary, virgin 4-day female    140 ovary, mated 4-day female    76 testis, mated 4-day male    5 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3  (33) central nervous system, pupae P8  (39) head, virgin 1-day female    19 head, virgin 4-day female    21 head, virgin 20-day female    21 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    18 head, mated 1-day male    24 head, mated 4-day male  (29) head, mated 20-day male  (32) salivary gland, larvae L3 wandering    15 salivary gland, white prepupae  (46) digestive system, larvae L3 wandering  (28) digestive system, 1-day adult    15 digestive system, 4-day adult    14 digestive system, 20-day adult    12 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8  (28) carcass, larvae L3 wandering    25 carcass, 1-day adult    12 carcass, 4-day adult    18 carcass, 20-day adult    17 ovary, virgin 4-day female  (140) ovary, mated 4-day female  (76) testis, mated 4-day male    5 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    33 central nervous system, pupae P8    39 head, virgin 1-day female    19 head, virgin 4-day female    21 head, virgin 20-day female    21 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    18 head, mated 1-day male    24 head, mated 4-day male    29 head, mated 20-day male    32 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    46 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    15 digestive system, 4-day adult    14 digestive system, 20-day adult    12 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    28 carcass, larvae L3 wandering    25 carcass, 1-day adult    12 carcass, 4-day adult    18 carcass, 20-day adult    17 ovary, virgin 4-day female  (140) ovary, mated 4-day female    76 testis, mated 4-day male    5 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    33 central nervous system, pupae P8    39 head, virgin 1-day female    19 head, virgin 4-day female    21 head, virgin 20-day female    21 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    18 head, mated 1-day male    24 head, mated 4-day male    29 head, mated 20-day male    32 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    46 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    15 digestive system, 4-day adult    14 digestive system, 20-day adult    12 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    28 carcass, larvae L3 wandering    25 carcass, 1-day adult    12 carcass, 4-day adult    18 carcass, 20-day adult    17 ovary, virgin 4-day female    140 ovary, mated 4-day female    76 testis, mated 4-day male    5 accessory gland, mated 4-day male    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    33 central nervous system, pupae P8    39 head, virgin 1-day female    19 head, virgin 4-day female    21 head, virgin 20-day female    21 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    18 head, mated 1-day male    24 head, mated 4-day male    29 head, mated 20-day male    32 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    46 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    15 digestive system, 4-day adult    14 digestive system, 20-day adult    12 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    28 carcass, larvae L3 wandering    25 carcass, 1-day adult    12 carcass, 4-day adult    18 carcass, 20-day adult    17 ovary, virgin 4-day female    140 ovary, mated 4-day female    76 testis, mated 4-day male    5 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3  (33) central nervous system, pupae P8  (39) head, virgin 1-day female    19 head, virgin 4-day female    21 head, virgin 20-day female    21 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    18 head, mated 1-day male    24 head, mated 4-day male  29 head, mated 20-day male  32 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae  (46) digestive system, larvae L3 wandering  28 digestive system, 1-day adult    15 digestive system, 4-day adult    14 digestive system, 20-day adult    12 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8  28 carcass, larvae L3 wandering    25 carcass, 1-day adult    12 carcass, 4-day adult    18 carcass, 20-day adult    17 ovary, virgin 4-day female  (140) ovary, mated 4-day female  (76) testis, mated 4-day male    5 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    33 central nervous system, pupae P8    39 head, virgin 1-day female    19 head, virgin 4-day female    21 head, virgin 20-day female    21 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    18 head, mated 1-day male    24 head, mated 4-day male    29 head, mated 20-day male    32 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    46 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    15 digestive system, 4-day adult    14 digestive system, 20-day adult    12 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    28 carcass, larvae L3 wandering    25 carcass, 1-day adult    12 carcass, 4-day adult    18 carcass, 20-day adult    17 ovary, virgin 4-day female  140 ovary, mated 4-day female    76 testis, mated 4-day male    5 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    33 central nervous system, pupae P8    39 head, virgin 1-day female    19 head, virgin 4-day female    21 head, virgin 20-day female    21 head, mated 1-day female    15 head, mated 4-day female    17 head, mated 20-day female    18 head, mated 1-day male    24 head, mated 4-day male    29 head, mated 20-day male    32 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    46 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    15 digestive system, 4-day adult    14 digestive system, 20-day adult    12 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    28 carcass, larvae L3 wandering    25 carcass, 1-day adult    12 carcass, 4-day adult    18 carcass, 20-day adult    17 ovary, virgin 4-day female    140 ovary, mated 4-day female    76 testis, mated 4-day male    5 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    40 embryo 02-04hr    34 embryo 04-06hr    18 embryo 06-08hr    21 embryo 08-10hr    31 embryo 10-12hr    27 embryo 12-14hr    44 embryo 14-16hr    12 embryo 16-18hr    25 embryo 18-20hr    12 embryo 20-22hr    26 embryo 22-24hr    37 larva L1    7 larva L2    10 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    24 white prepupae 24hr    25 pupae 2d postWPP    26 pupae 3d postWPP    15 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    6 adult male 30day    5 adult female 01day    8 adult female 05day    32 adult female 30day    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (40) embryo 02-04hr  (34) embryo 04-06hr    18 embryo 06-08hr    21 embryo 08-10hr  (31) embryo 10-12hr  (27) embryo 12-14hr  (44) embryo 14-16hr    12 embryo 16-18hr    25 embryo 18-20hr    12 embryo 20-22hr  26 embryo 22-24hr  (37) larva L1    7 larva L2    10 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9  (28) white prepupae new  26 white prepupae 12hr    24 white prepupae 24hr    25 pupae 2d postWPP  26 pupae 3d postWPP    15 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    6 adult male 30day    5 adult female 01day    8 adult female 05day  (32) adult female 30day    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    40 embryo 02-04hr    34 embryo 04-06hr    18 embryo 06-08hr    21 embryo 08-10hr    31 embryo 10-12hr    27 embryo 12-14hr    44 embryo 14-16hr    12 embryo 16-18hr    25 embryo 18-20hr    12 embryo 20-22hr    26 embryo 22-24hr    37 larva L1    7 larva L2    10 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    24 white prepupae 24hr    25 pupae 2d postWPP    26 pupae 3d postWPP    15 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    6 adult male 30day    5 adult female 01day    8 adult female 05day    32 adult female 30day    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    40 embryo 02-04hr    34 embryo 04-06hr    18 embryo 06-08hr    21 embryo 08-10hr    31 embryo 10-12hr    27 embryo 12-14hr    44 embryo 14-16hr    12 embryo 16-18hr    25 embryo 18-20hr    12 embryo 20-22hr    26 embryo 22-24hr    37 larva L1    7 larva L2    10 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    24 white prepupae 24hr    25 pupae 2d postWPP    26 pupae 3d postWPP    15 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    6 adult male 30day    5 adult female 01day    8 adult female 05day    32 adult female 30day    25 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    40 embryo 02-04hr    34 embryo 04-06hr    18 embryo 06-08hr    21 embryo 08-10hr    31 embryo 10-12hr    27 embryo 12-14hr    44 embryo 14-16hr    12 embryo 16-18hr    25 embryo 18-20hr    12 embryo 20-22hr    26 embryo 22-24hr    37 larva L1    7 larva L2    10 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    24 white prepupae 24hr    25 pupae 2d postWPP    26 pupae 3d postWPP    15 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    6 adult male 30day    5 adult female 01day    8 adult female 05day    32 adult female 30day    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (40) embryo 02-04hr  (34) embryo 04-06hr    18 embryo 06-08hr    21 embryo 08-10hr  31 embryo 10-12hr  27 embryo 12-14hr  (44) embryo 14-16hr    12 embryo 16-18hr    25 embryo 18-20hr    12 embryo 20-22hr  26 embryo 22-24hr  (37) larva L1    7 larva L2    10 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9  28 white prepupae new  26 white prepupae 12hr    24 white prepupae 24hr    25 pupae 2d postWPP  26 pupae 3d postWPP    15 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    6 adult male 30day    5 adult female 01day    8 adult female 05day  32 adult female 30day    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    40 embryo 02-04hr    34 embryo 04-06hr    18 embryo 06-08hr    21 embryo 08-10hr    31 embryo 10-12hr    27 embryo 12-14hr    44 embryo 14-16hr    12 embryo 16-18hr    25 embryo 18-20hr    12 embryo 20-22hr    26 embryo 22-24hr    37 larva L1    7 larva L2    10 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    24 white prepupae 24hr    25 pupae 2d postWPP    26 pupae 3d postWPP    15 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    6 adult male 30day    5 adult female 01day    8 adult female 05day    32 adult female 30day    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    40 embryo 02-04hr    34 embryo 04-06hr    18 embryo 06-08hr    21 embryo 08-10hr    31 embryo 10-12hr    27 embryo 12-14hr    44 embryo 14-16hr    12 embryo 16-18hr    25 embryo 18-20hr    12 embryo 20-22hr    26 embryo 22-24hr    37 larva L1    7 larva L2    10 larva L3 12hr old    7 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    28 white prepupae new    26 white prepupae 12hr    24 white prepupae 24hr    25 pupae 2d postWPP    26 pupae 3d postWPP    15 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    6 adult male 30day    5 adult female 01day    8 adult female 05day    32 adult female 30day    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    75 Schneider line 2 Sg4    38 embryonic 1182-4H    19 embryonic GM2    72 embryonic Kc167    44 embryonic S1    34 embryonic S3    52 leg disc CME L1    23 wing disc CME-W2    63 wing disc ML-DmD8    39 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    20 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    51 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2    57 ovary fGS/OSS    18 ovary OSC    27 ovary OSS    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (75) Schneider line 2 Sg4  (38) embryonic 1182-4H    19 embryonic GM2  (72) embryonic Kc167  (44) embryonic S1  (34) embryonic S3  (52) leg disc CME L1    23 wing disc CME-W2  (63) wing disc ML-DmD8  (39) wing disc ML-DmD9    13 wing disc ML-DmD16-c3  (33) wing disc ML-DmD21    20 wing disc ML-DmD32  (30) haltere disc ML-DmD17-c3  (51) eye-antennal disc ML-DmD11  (29) antennal disc ML-DmD20-c5  (52) mixed discs ML-DmD4-c1  (33) CNS ML-DmBG1-c1  (41) CNS ML-DmBG2-c2  (56) tumorous blood cells mbn2  (57) ovary fGS/OSS    18 ovary OSC  (27) ovary OSS    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    75 Schneider line 2 Sg4    38 embryonic 1182-4H    19 embryonic GM2    72 embryonic Kc167    44 embryonic S1    34 embryonic S3    52 leg disc CME L1    23 wing disc CME-W2    63 wing disc ML-DmD8    39 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    20 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    51 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2    57 ovary fGS/OSS    18 ovary OSC    27 ovary OSS    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    75 Schneider line 2 Sg4    38 embryonic 1182-4H    19 embryonic GM2    72 embryonic Kc167    44 embryonic S1    34 embryonic S3    52 leg disc CME L1    23 wing disc CME-W2    63 wing disc ML-DmD8    39 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    20 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    51 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2    57 ovary fGS/OSS    18 ovary OSC    27 ovary OSS    12 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    75 Schneider line 2 Sg4    38 embryonic 1182-4H    19 embryonic GM2    72 embryonic Kc167    44 embryonic S1    34 embryonic S3    52 leg disc CME L1    23 wing disc CME-W2    63 wing disc ML-DmD8    39 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    20 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    51 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2    57 ovary fGS/OSS    18 ovary OSC    27 ovary OSS    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (75) Schneider line 2 Sg4  (38) embryonic 1182-4H    19 embryonic GM2  (72) embryonic Kc167  (44) embryonic S1  (34) embryonic S3  (52) leg disc CME L1    23 wing disc CME-W2  (63) wing disc ML-DmD8  (39) wing disc ML-DmD9    13 wing disc ML-DmD16-c3  (33) wing disc ML-DmD21    20 wing disc ML-DmD32  30 haltere disc ML-DmD17-c3  (51) eye-antennal disc ML-DmD11  29 antennal disc ML-DmD20-c5  (52) mixed discs ML-DmD4-c1  (33) CNS ML-DmBG1-c1  (41) CNS ML-DmBG2-c2  (56) tumorous blood cells mbn2  (57) ovary fGS/OSS    18 ovary OSC  27 ovary OSS    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    75 Schneider line 2 Sg4    38 embryonic 1182-4H    19 embryonic GM2    72 embryonic Kc167    44 embryonic S1    34 embryonic S3    52 leg disc CME L1    23 wing disc CME-W2    63 wing disc ML-DmD8    39 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    20 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    51 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2    57 ovary fGS/OSS    18 ovary OSC    27 ovary OSS    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    75 Schneider line 2 Sg4    38 embryonic 1182-4H    19 embryonic GM2    72 embryonic Kc167    44 embryonic S1    34 embryonic S3    52 leg disc CME L1    23 wing disc CME-W2    63 wing disc ML-DmD8    39 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    20 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    51 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    41 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2    57 ovary fGS/OSS    18 ovary OSC    27 ovary OSS    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    36 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    64 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    68 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    61 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3  (36) Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult  (64) Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult  (68) Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult  (27) Ethanol 2.5% 3 hrs, larvae L3  (31) Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (61) Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult  (42) Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    36 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    64 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    68 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    61 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    36 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    64 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    68 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    61 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    36 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    64 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    68 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    61 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3  (36) Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult  (64) Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult  (68) Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult  27 Ethanol 2.5% 3 hrs, larvae L3  31 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (61) Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult  (42) Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    36 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    64 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    68 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    61 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    4 heat shock, 4-day adult    18 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    36 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    64 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    68 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    61 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_05 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • LD04957 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039994 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17082-RD
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG17082 Class Mutagen Stocks Known lesion CG17082MB06749 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG17082 Class Mutagen Stocks Known lesion CG17082KK114590 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)M41A2 (Myster et al., 2004) Df(2R)M41A8 (Myster et al., 2004) Df(2R)M41A10 (Myster et al., 2004) Df(2R)Nipped-D (Myster et al., 2004)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK114590} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system Mi{ET1}CG17082MB06749 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
signal transduction inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
intracellular inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG17082 - HIP-R anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG17082 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 78258 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039994 DroID - A comprehensive database of gene and protein interactions. • FBgn0039994 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 3355133
Orthologs
OrthoDB Orthologs (30) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6T1J65 Dipteran inclusive ortholog search EOG63R3VX Insect inclusive ortholog search EOG6NK9R6 Arthropod inclusive ortholog search EOG6CC2GV Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6T1J65)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG17082     Drosophila simulans   Dsim\GD11944     Drosophila erecta   Dere\GG21381     Drosophila yakuba   Dyak\GE20111     Drosophila pseudoobscura pseudoobscura   Dpse\GA29336     Drosophila persimilis   Dper\GL16234     Drosophila willistoni   Dwil\GK21943     Drosophila virilis   Dvir\GJ20424     Drosophila mojavensis   Dmoj\GI20674     Drosophila grimshawi   Dgri\GH20162
Orthologs in non-Drosophila Dipterans (EOG63R3VX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014901   Anopheles gambiae Malaria mosquito  Agam\AGAP008833   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ001770
Orthologs in non-Dipteran Insects (EOG6NK9R6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC408285   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG002071   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH19389   Atta cephalotes Leafcutter ant  Acep\ACEP27977   Atta cephalotes Leafcutter ant  Acep\ACEP27978   Camponotus floridanus Florida carpenter ant  Cflo\CFLO14789   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18324   Linepithema humile Argentine ant  Lhum\LH16628   Pogonomyrmex barbatus Red harvester ant  Pbar\PB10220   Solenopsis invicta Red fire ant  Sinv\SINV26131   Acyrthosiphon pisum Pea aphid  Apim\ACYPI006965   Bombyx mori Silkmoth  Bmor\BGIBMGA013521   Pediculus humanus Human body louse  Phum\PHUM503480   Tribolium castaneum Red flour beetle  Tcas\TC013626
Orthologs in non-Insect Arthropods (EOG6CC2GV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\rbcL   Ixodes scapularis Deer tick  Isca\ISCW000487   Ixodes scapularis Deer tick  Isca\ISCW000486
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	25522 w1118; Mi{ET1}CG17082MB06749
VDRC	v104232 P{KK114590}VIE-260B
Genomic Clones ( 2 )
	BACR03I06 BACR15A11 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 131 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD04957 RE22750 RE58280
Other clones	DPiM_LD04957 RH34608
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH08969 LD04154 LD08266 LD08837 LD15784 LD16910 LD27621 LD34572 RE01750 RE04744 RE10064 RE12768 RE16542 RE18231 RE19301 RE20380 RE20730 RE21836 RE23825 RE24781 RE25480 RE25674 RE26305 RE26650 RE28515 RE31359 RE32653 RE32682 RE33451 RE33523 RE34642 RE35214 RE35447 RE38396 RE42983 RE46932 RE49548 RE49725 RE52612 RE53572 RE54063 RE54779 RE62550 RE62563 RE62715 RE63866 RE63975 RE64833 RE66652 RE67141 RE67248 RE68887 RE69241 RE69463 RE72162 RE73184 SD13165 SD21404 SD22405
Other clones	20917 62294 66409 76558 77553 78619 153861 214255.44 214481.39 558127 CK01.28D.F3 CK01.68D.E3 CK01.80C.A2 CK01.81D.G2 CK01.86C.B10 CK01.89C.D3 CK01.96C.F4 CK01.111C.E10 CK01.116B.H10 Dmel_dig_016414_0631_1323 Dmel_neb_012954_0443_1683 EK031164 EK039363 EK055014 EK064428 EK068239 EK074954 EK135521 EK137522 EK187638 EK206434 EK208130 EK242951 EK244207 EK257429 EK267101 EN13038 EN13102 EP05902 EP09202 EP21324 EP21645 EP22349 FGM225C01 RP004094000 RP004120954 RP004125082 RP004148088 RP004175976 RP004180221 RP004198474 RP004203708 RP004217272 RP004223011 RP004231089 RP004247357 RP004250381 RP004266366 RP004280358 RP004330507 RP004414014 RP004442003 RP004454137 RP004492532 RP004524568 RP004531448 RP004540922
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039994 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 3355133
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG17082 BcDNA:LD04957 (FlyBase, 1996-)
Additional comments	Source for merge of CG17082 BcDNA:LD04957 was a shared cDNA (date:020730). (FlyBase, 1996-)
Other Comments
	Transiently named CG40286 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001042989 NM_001042990 NM_001042991 NM_001042992 NM_001042993 RefSeq (Proteins) • NP_001036454 NP_001036455 NP_001036456 NP_001036457 NP_001036458 DDBJ / EMBL / GenBank • AA201236 AA201744 AA390638 AA441024 AA536345 AA948923 AA990731 AABU01002769 EAA45990 EAA45991 EAA45992 EAA45993 EAA45994 EAA45995 Entrez Gene - A searchable database of RefSeq genes. • 3355133 UniProtKB/TrEMBL • Q0E9Q3 Q8T0G4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Rho GTPase-activating protein domain (IPR000198) Rho GTPase activation protein (IPR008936) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD04957
Linkouts
	BioGRID - A database of protein and genetic interactions • 78258 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0039994 DroID - A comprehensive database of gene and protein interactions. • FBgn0039994 DRSC - Results from RNAi screens. • FBgn0039994 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039994 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17082-RD FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039994 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 3355133 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 3355133 modMine - Data generated by the modENCODE project. • FBgn0039994
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	BcDNA:LD04957   CG17082 (Rossi et al., 2007, Keleman et al., 2009.8.5, Brandt, 2006, Di Stefano et al., 2011) CG40286 (Giot et al., 2003, )
Name Synonym
Secondary FlyBase IDs
	FBan0017082 FBgn0047230 FBgn0058286
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 5 ) Supplementary material  ( 4 ) Review  ( 1 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 2 ) Website  ( 1 )
Recent research papers ( 1 )
	Di Stefano et al., 2011, Genes Dev. 25(1): 17--28 Functional antagonism between histone H3K4 demethylases in vivo. [FBrf0212709] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...