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Gene Dmel\meso18E

General Information
Symbol	Dmel\meso18E	Species	D. melanogaster
Name	meso18E	Annotation symbol	CG14233
Feature type	protein_coding_gene	FlyBase ID	FBgn0040089
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	18E2-18E3	Sequence location	X:19,600,431..19,607,074 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene meso18E is referred to in FlyBase by the symbol Dmel\meso18E (CG14233, FBgn0040089). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: mesoderm development. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Homeodomain-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 06-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, adult fat body. Comments on Affy2 ProbeSet: ProbeSet 1636780_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of meso18E. Gene sequence location is X:19600431..19607074.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA20351 BKN30803
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 18E2-18E3   Limits computationally determined from genome sequence between P{EP}Sec61γEP1511 and P{EP}EP1116&P{EP}EP1344EP1344
Experimentally Determined Cytological Location
Cytogenetic map Notes References 18E-18E     (Taylor, 2000.2.2)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\meso18E for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Transposon inserted in intron
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) meso18E-RA FBtr0074812  NM_144358   2537   553 meso18E-RB FBtr0301703  NM_001169328   3092   553
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein meso18E-PA   FBpp0074581   61.4   553   6.62     NP_652615   AAF49011 meso18E-PB   FBpp0290917   61.4   553   6.62     NP_001162799   ACZ95333
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Homeodomain-like (IPR009057)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA941802   AE014298 AAF49011   AE014298 ACZ95333   AJ271814 CAB72133   AW942826   AY058570 AAL13799   BI162202   BI240576   BP547936   CL525965   CO189178   CO290680   CO308157   CO308504   CO330501   CO331131   CZ480218   EC064515   EC076499   EC203720   EC203756   EC216308   U85032
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9V3Z3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0040089    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0040089 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 06-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0040089 expression level Developmental Stage   Expression Level embryo 00-02hr    180 embryo 02-04hr    416 embryo 04-06hr    1949 embryo 06-08hr    3847 embryo 08-10hr    3563 embryo 10-12hr    5263 embryo 12-14hr    3007 embryo 14-16hr    1889 embryo 16-18hr    998 embryo 18-20hr    541 embryo 20-22hr    264 embryo 22-24hr    277 larva L1    569 larva L2    389 larva L3 12hr old    435 larva L3 puffstage 1-2    199 larva L3 puffstage 3-6    162 larva L3 puffstage 7-9    194 white prepupae new    274 white prepupae 12hr    310 white prepupae 24hr    1111 pupae 2d postWPP    876 pupae 3d postWPP    619 pupae 4d postWPP    767 adult male 01day    573 adult male 05day    636 adult male 30day    540 adult female 01day    549 adult female 05day    239 adult female 30day    285 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (180) embryo 02-04hr  (416) embryo 04-06hr  (1949) embryo 06-08hr  (3847) embryo 08-10hr  (3563) embryo 10-12hr  (5263) embryo 12-14hr  (3007) embryo 14-16hr  (1889) embryo 16-18hr  (998) embryo 18-20hr  (541) embryo 20-22hr  (264) embryo 22-24hr  (277) larva L1  (569) larva L2  (389) larva L3 12hr old  (435) larva L3 puffstage 1-2  (199) larva L3 puffstage 3-6  (162) larva L3 puffstage 7-9  (194) white prepupae new  (274) white prepupae 12hr  (310) white prepupae 24hr  (1111) pupae 2d postWPP  (876) pupae 3d postWPP  (619) pupae 4d postWPP  (767) adult male 01day  (573) adult male 05day  (636) adult male 30day  (540) adult female 01day  (549) adult female 05day  (239) adult female 30day  (285) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    180 embryo 02-04hr    416 embryo 04-06hr  (1949) embryo 06-08hr  (3847) embryo 08-10hr  (3563) embryo 10-12hr  (5263) embryo 12-14hr  (3007) embryo 14-16hr  (1889) embryo 16-18hr    998 embryo 18-20hr    541 embryo 20-22hr    264 embryo 22-24hr    277 larva L1    569 larva L2    389 larva L3 12hr old    435 larva L3 puffstage 1-2    199 larva L3 puffstage 3-6    162 larva L3 puffstage 7-9    194 white prepupae new    274 white prepupae 12hr    310 white prepupae 24hr    1111 pupae 2d postWPP    876 pupae 3d postWPP    619 pupae 4d postWPP    767 adult male 01day    573 adult male 05day    636 adult male 30day    540 adult female 01day    549 adult female 05day    239 adult female 30day    285 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    180 embryo 02-04hr    416 embryo 04-06hr    1949 embryo 06-08hr    3847 embryo 08-10hr    3563 embryo 10-12hr    5263 embryo 12-14hr    3007 embryo 14-16hr    1889 embryo 16-18hr    998 embryo 18-20hr    541 embryo 20-22hr    264 embryo 22-24hr    277 larva L1    569 larva L2    389 larva L3 12hr old    435 larva L3 puffstage 1-2    199 larva L3 puffstage 3-6    162 larva L3 puffstage 7-9    194 white prepupae new    274 white prepupae 12hr    310 white prepupae 24hr    1111 pupae 2d postWPP    876 pupae 3d postWPP    619 pupae 4d postWPP    767 adult male 01day    573 adult male 05day    636 adult male 30day    540 adult female 01day    549 adult female 05day    239 adult female 30day    285 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    180 embryo 02-04hr    416 embryo 04-06hr    1949 embryo 06-08hr    3847 embryo 08-10hr    3563 embryo 10-12hr    5263 embryo 12-14hr    3007 embryo 14-16hr    1889 embryo 16-18hr    998 embryo 18-20hr    541 embryo 20-22hr    264 embryo 22-24hr    277 larva L1    569 larva L2    389 larva L3 12hr old    435 larva L3 puffstage 1-2    199 larva L3 puffstage 3-6    162 larva L3 puffstage 7-9    194 white prepupae new    274 white prepupae 12hr    310 white prepupae 24hr    1111 pupae 2d postWPP    876 pupae 3d postWPP    619 pupae 4d postWPP    767 adult male 01day    573 adult male 05day    636 adult male 30day    540 adult female 01day    549 adult female 05day    239 adult female 30day    285 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0040089 expression level Developmental Stage   Expression Level embryo 00-02hr    180 embryo 02-04hr    416 embryo 04-06hr    1949 embryo 06-08hr    3847 embryo 08-10hr    3563 embryo 10-12hr    5263 embryo 12-14hr    3007 embryo 14-16hr    1889 embryo 16-18hr    998 embryo 18-20hr    541 embryo 20-22hr    264 embryo 22-24hr    277 larva L1    569 larva L2    389 larva L3 12hr old    435 larva L3 puffstage 1-2    199 larva L3 puffstage 3-6    162 larva L3 puffstage 7-9    194 white prepupae new    274 white prepupae 12hr    310 white prepupae 24hr    1111 pupae 2d postWPP    876 pupae 3d postWPP    619 pupae 4d postWPP    767 adult male 01day    573 adult male 05day    636 adult male 30day    540 adult female 01day    549 adult female 05day    239 adult female 30day    285 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (180) embryo 02-04hr  (416) embryo 04-06hr  (1949) embryo 06-08hr  (3847) embryo 08-10hr  (3563) embryo 10-12hr  (5263) embryo 12-14hr  (3007) embryo 14-16hr  (1889) embryo 16-18hr  (998) embryo 18-20hr  (541) embryo 20-22hr  (264) embryo 22-24hr  (277) larva L1  (569) larva L2  (389) larva L3 12hr old  (435) larva L3 puffstage 1-2  (199) larva L3 puffstage 3-6  (162) larva L3 puffstage 7-9  (194) white prepupae new  (274) white prepupae 12hr  (310) white prepupae 24hr  (1111) pupae 2d postWPP  (876) pupae 3d postWPP  (619) pupae 4d postWPP  (767) adult male 01day  (573) adult male 05day  (636) adult male 30day  (540) adult female 01day  (549) adult female 05day  (239) adult female 30day  (285) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    180 embryo 02-04hr    416 embryo 04-06hr  1949 embryo 06-08hr  (3847) embryo 08-10hr  (3563) embryo 10-12hr  (5263) embryo 12-14hr  (3007) embryo 14-16hr  1889 embryo 16-18hr    998 embryo 18-20hr    541 embryo 20-22hr    264 embryo 22-24hr    277 larva L1    569 larva L2    389 larva L3 12hr old    435 larva L3 puffstage 1-2    199 larva L3 puffstage 3-6    162 larva L3 puffstage 7-9    194 white prepupae new    274 white prepupae 12hr    310 white prepupae 24hr    1111 pupae 2d postWPP    876 pupae 3d postWPP    619 pupae 4d postWPP    767 adult male 01day    573 adult male 05day    636 adult male 30day    540 adult female 01day    549 adult female 05day    239 adult female 30day    285 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    180 embryo 02-04hr    416 embryo 04-06hr    1949 embryo 06-08hr    3847 embryo 08-10hr    3563 embryo 10-12hr    5263 embryo 12-14hr    3007 embryo 14-16hr    1889 embryo 16-18hr    998 embryo 18-20hr    541 embryo 20-22hr    264 embryo 22-24hr    277 larva L1    569 larva L2    389 larva L3 12hr old    435 larva L3 puffstage 1-2    199 larva L3 puffstage 3-6    162 larva L3 puffstage 7-9    194 white prepupae new    274 white prepupae 12hr    310 white prepupae 24hr    1111 pupae 2d postWPP    876 pupae 3d postWPP    619 pupae 4d postWPP    767 adult male 01day    573 adult male 05day    636 adult male 30day    540 adult female 01day    549 adult female 05day    239 adult female 30day    285 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    180 embryo 02-04hr    416 embryo 04-06hr    1949 embryo 06-08hr    3847 embryo 08-10hr    3563 embryo 10-12hr    5263 embryo 12-14hr    3007 embryo 14-16hr    1889 embryo 16-18hr    998 embryo 18-20hr    541 embryo 20-22hr    264 embryo 22-24hr    277 larva L1    569 larva L2    389 larva L3 12hr old    435 larva L3 puffstage 1-2    199 larva L3 puffstage 3-6    162 larva L3 puffstage 7-9    194 white prepupae new    274 white prepupae 12hr    310 white prepupae 24hr    1111 pupae 2d postWPP    876 pupae 3d postWPP    619 pupae 4d postWPP    767 adult male 01day    573 adult male 05day    636 adult male 30day    540 adult female 01day    549 adult female 05day    239 adult female 30day    285 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0040089    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0040089 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, adult fat body. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0040089 expression level Tissue   Expression Level Larval Central Nervous System    3.95 Larval Midgut no informative data Larval Hindgut    30 Larval Malpighian Tubules    3.6 Larval Fat Body    33.8 Larval Salivary Gland    9.5 Larval Trachea    7.2 Larval Carcass    57.325 Adult Head    33.3 Adult Eye    11.425 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    4 Adult Crop    104.8 Adult Midgut no informative data Adult Hindgut    38.1 Adult Malpighian Tubules    3 Adult Fat Body    110 Adult Salivary Gland    4.1 Adult Heart    70.175 Adult VirginFemale Spermatheca    29.4 Adult InseminatedFemale Spermatheca    56.5 Adult Ovary    17 Adult Testis    35.4 Adult Male Accessory Gland no informative data Adult Carcass    88.3 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    3.95 Larval Midgut no informative data Larval Hindgut    30 Larval Malpighian Tubules    3.6 Larval Fat Body    33.8 Larval Salivary Gland    9.5 Larval Trachea    7.2 Larval Carcass    57.325 Adult Head    33.3 Adult Eye    11.425 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    4 Adult Crop    104.8 Adult Midgut no informative data Adult Hindgut    38.1 Adult Malpighian Tubules    3 Adult Fat Body    110 Adult Salivary Gland    4.1 Adult Heart    70.175 Adult VirginFemale Spermatheca    29.4 Adult InseminatedFemale Spermatheca    56.5 Adult Ovary    17 Adult Testis    35.4 Adult Male Accessory Gland no informative data Adult Carcass    88.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    3.95 Larval Midgut no informative data Larval Hindgut    30 Larval Malpighian Tubules    3.6 Larval Fat Body    33.8 Larval Salivary Gland    9.5 Larval Trachea    7.2 Larval Carcass    57.325 Adult Head    33.3 Adult Eye    11.425 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    4 Adult Crop    104.8 Adult Midgut no informative data Adult Hindgut    38.1 Adult Malpighian Tubules    3 Adult Fat Body    110 Adult Salivary Gland    4.1 Adult Heart    70.175 Adult VirginFemale Spermatheca    29.4 Adult InseminatedFemale Spermatheca    56.5 Adult Ovary    17 Adult Testis    35.4 Adult Male Accessory Gland no informative data Adult Carcass    88.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3.95 Larval Midgut no informative data Larval Hindgut    30 Larval Malpighian Tubules    3.6 Larval Fat Body    33.8 Larval Salivary Gland    9.5 Larval Trachea    7.2 Larval Carcass    57.325 Adult Head    33.3 Adult Eye    11.425 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    4 Adult Crop    104.8 Adult Midgut no informative data Adult Hindgut    38.1 Adult Malpighian Tubules    3 Adult Fat Body    110 Adult Salivary Gland    4.1 Adult Heart    70.175 Adult VirginFemale Spermatheca    29.4 Adult InseminatedFemale Spermatheca    56.5 Adult Ovary    17 Adult Testis    35.4 Adult Male Accessory Gland no informative data Adult Carcass    88.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0040089 expression level Tissue   Expression Level Larval Central Nervous System    3.95 Larval Midgut no informative data Larval Hindgut    30 Larval Malpighian Tubules    3.6 Larval Fat Body    33.8 Larval Salivary Gland    9.5 Larval Trachea    7.2 Larval Carcass    57.325 Adult Head    33.3 Adult Eye    11.425 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    4 Adult Crop    104.8 Adult Midgut no informative data Adult Hindgut    38.1 Adult Malpighian Tubules    3 Adult Fat Body    110 Adult Salivary Gland    4.1 Adult Heart    70.175 Adult VirginFemale Spermatheca    29.4 Adult InseminatedFemale Spermatheca    56.5 Adult Ovary    17 Adult Testis    35.4 Adult Male Accessory Gland no informative data Adult Carcass    88.3 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    3.95 Larval Midgut no informative data Larval Hindgut    30 Larval Malpighian Tubules    3.6 Larval Fat Body    33.8 Larval Salivary Gland    9.5 Larval Trachea    7.2 Larval Carcass    57.325 Adult Head    33.3 Adult Eye    11.425 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    4 Adult Crop    104.8 Adult Midgut no informative data Adult Hindgut    38.1 Adult Malpighian Tubules    3 Adult Fat Body    110 Adult Salivary Gland    4.1 Adult Heart    70.175 Adult VirginFemale Spermatheca    29.4 Adult InseminatedFemale Spermatheca    56.5 Adult Ovary    17 Adult Testis    35.4 Adult Male Accessory Gland no informative data Adult Carcass    88.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    3.95 Larval Midgut no informative data Larval Hindgut    30 Larval Malpighian Tubules    3.6 Larval Fat Body    33.8 Larval Salivary Gland    9.5 Larval Trachea    7.2 Larval Carcass    57.325 Adult Head    33.3 Adult Eye    11.425 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    4 Adult Crop    104.8 Adult Midgut no informative data Adult Hindgut    38.1 Adult Malpighian Tubules    3 Adult Fat Body    110 Adult Salivary Gland    4.1 Adult Heart    70.175 Adult VirginFemale Spermatheca    29.4 Adult InseminatedFemale Spermatheca    56.5 Adult Ovary    17 Adult Testis    35.4 Adult Male Accessory Gland no informative data Adult Carcass    88.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3.95 Larval Midgut no informative data Larval Hindgut    30 Larval Malpighian Tubules    3.6 Larval Fat Body    33.8 Larval Salivary Gland    9.5 Larval Trachea    7.2 Larval Carcass    57.325 Adult Head    33.3 Adult Eye    11.425 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    4 Adult Crop    104.8 Adult Midgut no informative data Adult Hindgut    38.1 Adult Malpighian Tubules    3 Adult Fat Body    110 Adult Salivary Gland    4.1 Adult Heart    70.175 Adult VirginFemale Spermatheca    29.4 Adult InseminatedFemale Spermatheca    56.5 Adult Ovary    17 Adult Testis    35.4 Adult Male Accessory Gland no informative data Adult Carcass    88.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    33.3   NA  Eye    11.425   NA  Brain    6   3.95  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    4   NA  Crop    104.8   no informative data  Midgut    no informative data   30  Hindgut    38.1   3.6  Malpighian Tubules    3   33.8  Fat Body    110   9.5  Salivary Gland    4.1   NA  Heart    70.175   7.2  Trachea    NA   NA  VirginFemale Spermatheca    29.4   NA  InseminatedFemale Spermatheca    56.5   NA  Ovary    17   NA  Testis    35.4   NA  Male Accessory Gland    no informative data   57.325  Carcass    88.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_31
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040089 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14233-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for meso18E Stages(s) 9-10 Stages(s) 11-12
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable meso18EEY07842 viable, with Scer\GAL4pnr-MD237 meso18EGD8270 Sterility Allele fertile meso18EEY07842 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of meso18E Class Mutagen Stocks Known lesion meso18Ee02398 piggyBac transposase 1 -- meso18EEY07842 P-element activity 1 -- meso18EGG01573 0 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of meso18E Class Mutagen Stocks Known lesion meso18EGD8270 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6253 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD8270} NA reporter construct P{meso18E-lacZ.CRM} No
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}meso18EEY07842 NA P{Mae-UAS.6.11}meso18EGG01573 NA miscellaneous insertions PBac{RB}meso18Ee02398 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
mesoderm development inferred from expression pattern (Furlong et al., 2001)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions meso18E allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 72734 DroID - A comprehensive database of gene and protein interactions. • FBgn0040089 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 53448
Orthologs
Genome-wide drosophilid orthologs	Dana\GF20467 Dere\GG18027 Dgri\GH12254 Dmoj\GI11014 Dper\GL18303 Dpse\GA12846 Dsec\GM22710 Dvir\GJ15613 Dwil\GK15888 Dyak\GE17356
Curated drosophilid orthologs	Dpse\GA12846
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0234826 FBgn0217891 FBgn0202803 FBgn0177580 FBgn0072891 FBgn0155905 FBgn0133777 FBgn0119733 FBgn0110245 FBgn0097474 ACYPI45401
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	17411 y1 w67c23 P{EPgy2}meso18EEY07842
Harvard	- PBac{RB}meso18Ee02398
VDRC	v17444 w1118; P{GD8270}v17444/TM3
Genomic Clones ( 1 )
	BACR33M08 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 15 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD26007
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE01581 RE37449
Other clones	84141 105334 153409 154034 192267 EK043338 EK074747 EK256845 EK258534 EK295424 EK298442 FGH122C06
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0040089 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 53448
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: meso18E anon-18DEd (Bayraktaroglu, 2000.11.2) Source for merge of: meso18E CG14233 (Bayraktaroglu, 2000.8.7)
Additional comments
Other Comments
	ChEST reveals this is a target of Mef2. (Junion et al., 2005) Not known to correspond to any of the known lethal complementation groups in 18D-18E region. (Fehon, 1997.3.25)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_144358 NM_001169328 RefSeq (Proteins) • NP_652615 NP_001162799 DDBJ / EMBL / GenBank • AA941802 AAF49011 AAL13799 ACZ95333 AJ271814 AW942826 AY058570 CAB72133 CL525965 CZ480218 U85032 Entrez Gene - A searchable database of RefSeq genes. • 53448 UniProtKB/TrEMBL • Q9V3Z3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Homeodomain-like (IPR009057)
Linkouts
	BioGRID - A database of protein and genetic interactions • 72734 DroID - A comprehensive database of gene and protein interactions. • FBgn0040089 DRSC - Results from RNAi screens. • FBgn0040089 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040089 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14233-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0040089 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 53448 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 53448 modMine - Data generated by the modENCODE project. • FBgn0040089 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0234826 FBgn0217891 FBgn0202803 FBgn0177580 FBgn0072891 FBgn0155905 FBgn0133777 FBgn0119733 FBgn0110245 FBgn0097474 ACYPI45401 REDfly - A database of transcriptional regulatory elements. • FBgn0040089
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	anon-18DEd   CG14233 (Quinones-Coello, 2007) Dmeso18E (Baylies and Michelson, 2001) eso18E   ld26007 (Herold et al., 2003) Meso18E (Junion et al., 2005) meso18E (Quinones-Coello, 2007, Sandmann et al., 2006, Hudson et al., 2008, Junion et al., 2007) Mmeso18E (Taylor, 2000)
Name Synonym	meso18E
Secondary FlyBase IDs
	FBgn0019899 FBgn0031063 FBgn0040223
References ( 24 )
Generate a list of	All references relating to this gene ( 24 )
List References by type	Research paper  ( 8 ) Supplementary material  ( 4 ) Review  ( 1 ) Personal communication to FlyBase  ( 5 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...
Recent reviews (0)
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