Neu5
Please see the JBrowse view of Dmel\Sulf1 for information on other features
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Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
Antisense UTR: 5' UTR of one isoform is antisense to CG44044 on opposite strand.
The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sulf1 using the Feature Mapper tool.
Comment: maternally deposited
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: reported as ventral nerve cord anlage
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: weaker
Comment: stronger
Comment: stronger
Comment: weaker
Sulf1 is expressed in all provein regions in the wing imaginal disc.
Sulf1 is first detected in early first instar larvae in the central region of the wing pouch and in several spots located in the notum region of the disc. In the pouch, expression is further patterned during mid- to late- third instar stages. The domain in the central region of the wing pouch appears much broader. At late third instar larval stages, regionalization of the Sulf1 epxression domain occurs, defining stripes along the AP and DV axes reminiscent of provein domains L1 to L5. A lower level of staining is seen in the presumptive L3-L4 intervein region. Comparison to kn and dpp markers shows that expression is initially restricted to the anterior compartment but starting in mid-third instar larval stages extends to the posterior compartment. At the late third instar larval stage, Sulf1 is highly expressed in the L3 and L4 provein domains. In addition, expression is seen in L2 and L5 proveins and along the DV boundary.
Sulf1 is expressed at the morphogenetic furrow and in the central brain region in larvae. It is also expressed at high levels near the AP and DV compartment boundaries in wing discs.
Sulf1 displays weak and non-uniform staining in the lateral neurogenic ectoderm.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Sulf1 in GBrowse 23-58
3-58
3-58.3
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Sulf1 CG6725