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Gene Dmel\CG3711

General Information
Symbol	Dmel\CG3711	Species	D. melanogaster
Name		Annotation symbol	CG3711
Feature type	protein_coding_gene	FlyBase ID	FBgn0040344
Gene Model Status	Current	Stock availability	7 publicly available
Also Known As	EG:BACR7A4.19
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	1D2-1D2	Sequence location	X:817,201..821,615 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG3711 (FBgn0040344). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: BTB/POZ; BTB/POZ fold; BTB/POZ-like; Galactose oxidase, beta-propeller; Kelch repeat type 1; Kelch-type beta propeller. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1623320_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG3711. Gene sequence location is X:817201..821628.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 1D2-1D2   Limits computationally determined from genome sequence between P{EP}EP1600&P{EP}EP1498 and P{EP}EP1615&P{EP}EP964
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG3711 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	gene_with_stop_codon_read_through ; SO:0000697 Low-frequency junction(s) not annotated. Gene model reviewed during 5.44 Stop-codon suppression (UAG) postulated; FBrf0216884. Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG3711-RA FBtr0070191  NM_130513   4056   975 CG3711-RC FBtr0331302  NM_001038730   3822   975 CG3711-RD FBtr0331303  NM_001272185   4056   998
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG3711-PA   FBpp0070184   106.4   975   7.96     NP_569869   AAF45563 CG3711-PC   FBpp0303734   106.4   975   7.96     NP_001033819   ABC67162 CG3711-PD   FBpp0303735   108.9   998   8.11     NP_001259114   AGB94960
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • BTB/POZ-like (IPR000210) Kelch repeat type 1 (IPR006652) BTB/POZ (IPR013069) BTB/POZ fold (IPR011333) Kelch-type beta propeller (IPR015915) Galactose oxidase, beta-propeller (IPR015916)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF45563   AE014298 ABC67162   AE014298 AGB94960   AI114282   AI258251   AI260682   AI404002   AI945997   AL109630 CAB65872   AW943971   AY069715 AAL39860   BI214498   CK661238   CO265937   CO296854   CO310900   CO315126   CO319185   CO319583   CO329224   CZ488778   EC089909   EC204542   EC209773   EC233466   EC236310   EC239311   EC248058   GH944048   GH944517   GH964013   GH968464   GH971538   GH977121   GH982962
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9V410 Q8SZY2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    176.2 Larval Midgut    48.8 Larval Hindgut    79.3 Larval Malpighian Tubules    53.3 Larval Fat Body    53.2 Larval Salivary Gland    160.9 Larval Trachea    127.9 Larval Carcass    67.6 Adult Head    165.8 Adult Eye    113.925 Adult Brain    432.1 Adult Thoracic-Abdominal Ganglion    417.2 Adult Crop    100.2 Adult Midgut    51.6 Adult Hindgut    66.3 Adult Malpighian Tubules    40.2 Adult Fat Body    39.1 Adult Salivary Gland    214.6 Adult Heart    44.625 Adult VirginFemale Spermatheca    56.6 Adult InseminatedFemale Spermatheca    61.5 Adult Ovary    159.6 Adult Testis    35.6 Adult Male Accessory Gland    129.9 Adult Carcass    55.5 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    176.2 Larval Midgut    48.8 Larval Hindgut    79.3 Larval Malpighian Tubules    53.3 Larval Fat Body    53.2 Larval Salivary Gland    160.9 Larval Trachea    127.9 Larval Carcass    67.6 Adult Head    165.8 Adult Eye    113.925 Adult Brain    432.1 Adult Thoracic-Abdominal Ganglion    417.2 Adult Crop    100.2 Adult Midgut    51.6 Adult Hindgut    66.3 Adult Malpighian Tubules    40.2 Adult Fat Body    39.1 Adult Salivary Gland    214.6 Adult Heart    44.625 Adult VirginFemale Spermatheca    56.6 Adult InseminatedFemale Spermatheca    61.5 Adult Ovary    159.6 Adult Testis    35.6 Adult Male Accessory Gland    129.9 Adult Carcass    55.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    176.2 Larval Midgut    48.8 Larval Hindgut    79.3 Larval Malpighian Tubules    53.3 Larval Fat Body    53.2 Larval Salivary Gland    160.9 Larval Trachea    127.9 Larval Carcass    67.6 Adult Head    165.8 Adult Eye    113.925 Adult Brain    432.1 Adult Thoracic-Abdominal Ganglion    417.2 Adult Crop    100.2 Adult Midgut    51.6 Adult Hindgut    66.3 Adult Malpighian Tubules    40.2 Adult Fat Body    39.1 Adult Salivary Gland    214.6 Adult Heart    44.625 Adult VirginFemale Spermatheca    56.6 Adult InseminatedFemale Spermatheca    61.5 Adult Ovary    159.6 Adult Testis    35.6 Adult Male Accessory Gland    129.9 Adult Carcass    55.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    176.2 Larval Midgut    48.8 Larval Hindgut    79.3 Larval Malpighian Tubules    53.3 Larval Fat Body    53.2 Larval Salivary Gland    160.9 Larval Trachea    127.9 Larval Carcass    67.6 Adult Head    165.8 Adult Eye    113.925 Adult Brain    432.1 Adult Thoracic-Abdominal Ganglion    417.2 Adult Crop    100.2 Adult Midgut    51.6 Adult Hindgut    66.3 Adult Malpighian Tubules    40.2 Adult Fat Body    39.1 Adult Salivary Gland    214.6 Adult Heart    44.625 Adult VirginFemale Spermatheca    56.6 Adult InseminatedFemale Spermatheca    61.5 Adult Ovary    159.6 Adult Testis    35.6 Adult Male Accessory Gland    129.9 Adult Carcass    55.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    176.2 Larval Midgut    48.8 Larval Hindgut    79.3 Larval Malpighian Tubules    53.3 Larval Fat Body    53.2 Larval Salivary Gland    160.9 Larval Trachea    127.9 Larval Carcass    67.6 Adult Head    165.8 Adult Eye    113.925 Adult Brain    432.1 Adult Thoracic-Abdominal Ganglion    417.2 Adult Crop    100.2 Adult Midgut    51.6 Adult Hindgut    66.3 Adult Malpighian Tubules    40.2 Adult Fat Body    39.1 Adult Salivary Gland    214.6 Adult Heart    44.625 Adult VirginFemale Spermatheca    56.6 Adult InseminatedFemale Spermatheca    61.5 Adult Ovary    159.6 Adult Testis    35.6 Adult Male Accessory Gland    129.9 Adult Carcass    55.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    176.2 Larval Midgut    48.8 Larval Hindgut    79.3 Larval Malpighian Tubules    53.3 Larval Fat Body    53.2 Larval Salivary Gland    160.9 Larval Trachea    127.9 Larval Carcass    67.6 Adult Head    165.8 Adult Eye    113.925 Adult Brain    432.1 Adult Thoracic-Abdominal Ganglion    417.2 Adult Crop    100.2 Adult Midgut    51.6 Adult Hindgut    66.3 Adult Malpighian Tubules    40.2 Adult Fat Body    39.1 Adult Salivary Gland    214.6 Adult Heart    44.625 Adult VirginFemale Spermatheca    56.6 Adult InseminatedFemale Spermatheca    61.5 Adult Ovary    159.6 Adult Testis    35.6 Adult Male Accessory Gland    129.9 Adult Carcass    55.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    176.2 Larval Midgut    48.8 Larval Hindgut    79.3 Larval Malpighian Tubules    53.3 Larval Fat Body    53.2 Larval Salivary Gland    160.9 Larval Trachea    127.9 Larval Carcass    67.6 Adult Head    165.8 Adult Eye    113.925 Adult Brain    432.1 Adult Thoracic-Abdominal Ganglion    417.2 Adult Crop    100.2 Adult Midgut    51.6 Adult Hindgut    66.3 Adult Malpighian Tubules    40.2 Adult Fat Body    39.1 Adult Salivary Gland    214.6 Adult Heart    44.625 Adult VirginFemale Spermatheca    56.6 Adult InseminatedFemale Spermatheca    61.5 Adult Ovary    159.6 Adult Testis    35.6 Adult Male Accessory Gland    129.9 Adult Carcass    55.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    176.2 Larval Midgut    48.8 Larval Hindgut    79.3 Larval Malpighian Tubules    53.3 Larval Fat Body    53.2 Larval Salivary Gland    160.9 Larval Trachea    127.9 Larval Carcass    67.6 Adult Head    165.8 Adult Eye    113.925 Adult Brain    432.1 Adult Thoracic-Abdominal Ganglion    417.2 Adult Crop    100.2 Adult Midgut    51.6 Adult Hindgut    66.3 Adult Malpighian Tubules    40.2 Adult Fat Body    39.1 Adult Salivary Gland    214.6 Adult Heart    44.625 Adult VirginFemale Spermatheca    56.6 Adult InseminatedFemale Spermatheca    61.5 Adult Ovary    159.6 Adult Testis    35.6 Adult Male Accessory Gland    129.9 Adult Carcass    55.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    165.8   NA  Eye    113.925   NA  Brain    432.1   176.2  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    417.2   NA  Crop    100.2   48.8  Midgut    51.6   79.3  Hindgut    66.3   53.3  Malpighian Tubules    40.2   53.2  Fat Body    39.1   160.9  Salivary Gland    214.6   NA  Heart    44.625   127.9  Trachea    NA   NA  VirginFemale Spermatheca    56.6   NA  InseminatedFemale Spermatheca    61.5   NA  Ovary    159.6   NA  Testis    35.6   NA  Male Accessory Gland    129.9   67.6  Carcass    55.5 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    14 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    10 head, mated 4-day female    12 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    21 head, mated 20-day male    24 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    3 digestive system, 20-day adult    4 fat body, larvae L3 wandering    1 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    15 ovary, mated 4-day female    10 testis, mated 4-day male    5 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    14 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    10 head, mated 4-day female    12 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    21 head, mated 20-day male    24 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    3 digestive system, 20-day adult    4 fat body, larvae L3 wandering    1 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    15 ovary, mated 4-day female    10 testis, mated 4-day male    5 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    14 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    10 head, mated 4-day female    12 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    21 head, mated 20-day male    24 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    3 digestive system, 20-day adult    4 fat body, larvae L3 wandering    1 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    15 ovary, mated 4-day female    10 testis, mated 4-day male    5 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    14 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    10 head, mated 4-day female    12 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    21 head, mated 20-day male    24 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    3 digestive system, 20-day adult    4 fat body, larvae L3 wandering    1 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    15 ovary, mated 4-day female    10 testis, mated 4-day male    5 accessory gland, mated 4-day male    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    14 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    10 head, mated 4-day female    12 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    21 head, mated 20-day male    24 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    3 digestive system, 20-day adult    4 fat body, larvae L3 wandering    1 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    15 ovary, mated 4-day female    10 testis, mated 4-day male    5 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    14 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    10 head, mated 4-day female    12 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    21 head, mated 20-day male    24 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    3 digestive system, 20-day adult    4 fat body, larvae L3 wandering    1 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    15 ovary, mated 4-day female    10 testis, mated 4-day male    5 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    14 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    10 head, mated 4-day female    12 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    21 head, mated 20-day male    24 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    3 digestive system, 20-day adult    4 fat body, larvae L3 wandering    1 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    15 ovary, mated 4-day female    10 testis, mated 4-day male    5 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    14 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    13 head, virgin 20-day female    16 head, mated 1-day female    10 head, mated 4-day female    12 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    21 head, mated 20-day male    24 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    3 digestive system, 20-day adult    4 fat body, larvae L3 wandering    1 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    3 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    15 ovary, mated 4-day female    10 testis, mated 4-day male    5 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    5 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    12 embryo 10-12hr    11 embryo 12-14hr    10 embryo 14-16hr    10 embryo 16-18hr    8 embryo 18-20hr    8 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    11 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    7 adult male 01day    10 adult male 05day    12 adult male 30day    13 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    5 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    12 embryo 10-12hr    11 embryo 12-14hr    10 embryo 14-16hr    10 embryo 16-18hr    8 embryo 18-20hr    8 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    11 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    7 adult male 01day    10 adult male 05day    12 adult male 30day    13 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    5 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    12 embryo 10-12hr    11 embryo 12-14hr    10 embryo 14-16hr    10 embryo 16-18hr    8 embryo 18-20hr    8 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    11 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    7 adult male 01day    10 adult male 05day    12 adult male 30day    13 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    5 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    12 embryo 10-12hr    11 embryo 12-14hr    10 embryo 14-16hr    10 embryo 16-18hr    8 embryo 18-20hr    8 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    11 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    7 adult male 01day    10 adult male 05day    12 adult male 30day    13 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    5 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    12 embryo 10-12hr    11 embryo 12-14hr    10 embryo 14-16hr    10 embryo 16-18hr    8 embryo 18-20hr    8 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    11 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    7 adult male 01day    10 adult male 05day    12 adult male 30day    13 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    5 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    12 embryo 10-12hr    11 embryo 12-14hr    10 embryo 14-16hr    10 embryo 16-18hr    8 embryo 18-20hr    8 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    11 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    7 adult male 01day    10 adult male 05day    12 adult male 30day    13 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    5 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    12 embryo 10-12hr    11 embryo 12-14hr    10 embryo 14-16hr    10 embryo 16-18hr    8 embryo 18-20hr    8 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    11 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    7 adult male 01day    10 adult male 05day    12 adult male 30day    13 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    5 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    12 embryo 10-12hr    11 embryo 12-14hr    10 embryo 14-16hr    10 embryo 16-18hr    8 embryo 18-20hr    8 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    11 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    10 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    14 pupae 3d postWPP    11 pupae 4d postWPP    7 adult male 01day    10 adult male 05day    12 adult male 30day    13 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    13 embryonic 1182-4H    13 embryonic GM2    11 embryonic Kc167    18 embryonic S1    17 embryonic S3    14 leg disc CME L1    11 wing disc CME-W2    11 wing disc ML-DmD8    15 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    12 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    15 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    13 embryonic 1182-4H    13 embryonic GM2    11 embryonic Kc167    18 embryonic S1    17 embryonic S3    14 leg disc CME L1    11 wing disc CME-W2    11 wing disc ML-DmD8    15 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    12 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    15 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    13 embryonic 1182-4H    13 embryonic GM2    11 embryonic Kc167    18 embryonic S1    17 embryonic S3    14 leg disc CME L1    11 wing disc CME-W2    11 wing disc ML-DmD8    15 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    12 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    15 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    13 embryonic 1182-4H    13 embryonic GM2    11 embryonic Kc167    18 embryonic S1    17 embryonic S3    14 leg disc CME L1    11 wing disc CME-W2    11 wing disc ML-DmD8    15 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    12 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    15 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    13 embryonic 1182-4H    13 embryonic GM2    11 embryonic Kc167    18 embryonic S1    17 embryonic S3    14 leg disc CME L1    11 wing disc CME-W2    11 wing disc ML-DmD8    15 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    12 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    15 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    13 embryonic 1182-4H    13 embryonic GM2    11 embryonic Kc167    18 embryonic S1    17 embryonic S3    14 leg disc CME L1    11 wing disc CME-W2    11 wing disc ML-DmD8    15 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    12 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    15 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    13 embryonic 1182-4H    13 embryonic GM2    11 embryonic Kc167    18 embryonic S1    17 embryonic S3    14 leg disc CME L1    11 wing disc CME-W2    11 wing disc ML-DmD8    15 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    12 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    15 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    13 embryonic 1182-4H    13 embryonic GM2    11 embryonic Kc167    18 embryonic S1    17 embryonic S3    14 leg disc CME L1    11 wing disc CME-W2    11 wing disc ML-DmD8    15 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    12 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    15 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    11 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    11 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    11 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    11 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    11 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    11 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    11 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    11 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_27
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040344 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3711-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG3711GD4339 CG3711GD4892 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG3711 Class Mutagen Stocks Known lesion CG3711f06128 piggyBac transposase 1 -- CG3711MB12128 1 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG3711 Class Mutagen Stocks Known lesion CG3711GD4339 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG3711GD4892 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG3711HMS00306 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG3711NIG.3711R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6224 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4339} NA P{GD4892} NA P{NIG.3711R} NA P{TRiP.HMS00306} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}KG06662 NA PBac{WH}CG3711f06128 NA insertion of mobile activating element P{Mae-UAS.6.11}GG01477GG01477 NA insertion of enhancer trap binary system Mi{ET1}CG3711MB12128 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
sequence-specific DNA binding transcription factor activity inferred from sequence or structural similarity with EMBL:U53925 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
nucleus inferred from sequence or structural similarity with EMBL:U53925 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	gene_with_edited_transcript (Graveley et al., 2011) gene_with_stop_codon_read_through (Jungreis et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG3711 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 57605 DroID - A comprehensive database of gene and protein interactions. • FBgn0040344 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31037
Orthologs
OrthoDB Orthologs (43) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6HQF3S Dipteran inclusive ortholog search EOG6FJ8HX Insect inclusive ortholog search EOG6DFNHG Arthropod inclusive ortholog search EOG6280GN Metazoa inclusive ortholog search EOG6NWBC4
Orthologs in Drosophila Species (EOG6HQF3S)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG3711     Drosophila simulans   Dsim\GD16450 Y   Drosophila sechellia   Dsec\GM19013 Y   Drosophila erecta   Dere\GG12733 Y   Drosophila yakuba   Dyak\GE16559 Y   Drosophila ananassae   Dana\GF22052 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA17633 Y   Drosophila persimilis   Dper\GL14422 Y   Drosophila willistoni   Dwil\GK10175 Y   Drosophila virilis   Dvir\GJ15361 Y   Drosophila mojavensis   Dmoj\GI15003 Y   Drosophila grimshawi   Dgri\GH12418 Y
Orthologs in non-Drosophila Dipterans (EOG6FJ8HX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000925   Anopheles gambiae Malaria mosquito  Agam\AGAP004292   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ017663
Orthologs in non-Dipteran Insects (EOG6DFNHG)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LZTR1   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG000646   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH10391   Atta cephalotes Leafcutter ant  Acep\ACEP23420   Camponotus floridanus Florida carpenter ant  Cflo\CFLO22820   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL16196   Linepithema humile Argentine ant  Lhum\LH18656   Pogonomyrmex barbatus Red harvester ant  Pbar\PB23640   Pogonomyrmex barbatus Red harvester ant  Pbar\PB23641   Solenopsis invicta Red fire ant  Sinv\SINV20924   Acyrthosiphon pisum Pea aphid  Apim\ACYPI21448   Acyrthosiphon pisum Pea aphid  Apim\ACYPI21620   Acyrthosiphon pisum Pea aphid  Apim\ACYPI083937   Acyrthosiphon pisum Pea aphid  Apim\ACYPI49569   Bombyx mori Silkmoth  Bmor\BGIBMGA012932   Pediculus humanus Human body louse  Phum\PHUM449130   Tribolium castaneum Red flour beetle  Tcas\GLEAN_08426
Orthologs in non-Insect Arthropods (EOG6280GN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Dcaf11   Ixodes scapularis Deer tick  Isca\ISCW013315
Orthologs in non-Arthropod Metazoa (EOG6NWBC4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016401gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008405gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005886gn   Danio rerio Zebrafish  Drer\lztr1   Xenopus tropicalis Western clawed frog  Xtro\lztr1   Gallus gallus Domestic chicken  Ggal\LZTR1   Mus musculus House mouse  Mmus\Lztr1   Rattus norvegicus Norway rat  Rnor\Lztr1   Homo sapiens Human  Hsap\LZTR1
Human Orthologs (1)
Gene OMIM HGNC Hsap\LZTR1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD16450 Drosophila sechellia Dsec\GM19013 Drosophila erecta Dere\GG12733 Drosophila yakuba Dyak\GE16559 Drosophila ananassae Dana\GF22052 Drosophila pseudoobscura pseudoobscura Dpse\GA17633 Drosophila persimilis Dper\GL14422 Drosophila willistoni Dwil\GK10175 Drosophila virilis Dvir\GJ15361 Drosophila mojavensis Dmoj\GI15003 Drosophila grimshawi Dgri\GH12418
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	29940 Mi{ET1}CG3711MB12128 w1118 33422 y1 sc* v1; P{TRiP.HMS00306}attP2
Harvard	- PBac{WH}CG3711f06128
VDRC	v11164 w1118; P{GD4339}v11164 v11166 w1118; P{GD4339}v11166 v13008 w1118; P{GD4892}v13008 v13007 w1118; P{GD4892}v13007/CyO
Genomic Clones ( 1 )
	BACR05N14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 26 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LP01394
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH11077 GH23572 LP04635 LP20544 RE20324
Other clones	30160 34494 82000 100325 175406 190171 EK144513 EK215310 EK222932 EK239209 EK276521 EK279240 EK292311 RP004215755 RP004240559 RP004245544 RP004301412 RP004411061 RP004454580 RP004508928
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0040344 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31037
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: EG:BACR7A4.19 CG3711 (FlyBase, 1996-)
Additional comments	Source for merge of EG:BACR7A4.19 CG3711 was sequence comparison (date:000425). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_130513 NM_001038730 NM_001272185 RefSeq (Proteins) • NP_569869 NP_001033819 NP_001259114 DDBJ / EMBL / GenBank • AAF45563 AAF45563.1 AAL39860 ABC67162 AGB94960 AI258251 AI945997 AL109630 AW943971 AY069715 CAB65872 CZ488778 Entrez Gene - A searchable database of RefSeq genes. • 31037 UniProtKB/TrEMBL • Q8SZY2 Q9V410
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • BTB/POZ-like (IPR000210) Kelch repeat type 1 (IPR006652) BTB/POZ (IPR013069) BTB/POZ fold (IPR011333) Kelch-type beta propeller (IPR015915) Galactose oxidase, beta-propeller (IPR015916)
Linkouts
	BioGRID - A database of protein and genetic interactions • 57605 DroID - A comprehensive database of gene and protein interactions. • FBgn0040344 DRSC - Results from RNAi screens. • FBgn0040344 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040344 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3711-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0040344 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31037 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31037 modMine - Data generated by the modENCODE project. • FBgn0040344
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG3711 (Legube et al., 2006, Grieder et al., 2007, Jungreis et al., 2011, Ni et al., 2010.12.1, Wasbrough et al., 2010, Japanese National Institute of Genetics, 2012.5.21) EG:BACR7A4.19 (Benos et al., 2001, Giot et al., 2003, )
Name Synonym
Secondary FlyBase IDs
	FBgn0029540
References ( 24 )
Generate a list of	All references relating to this gene ( 24 )
List References by type	Research paper  ( 2 ) Supplementary material  ( 7 ) Personal communication to FlyBase  ( 10 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...