Gene Dmel\CG11380

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General Information

Symbol

Dmel\CG11380

Species

D. melanogaster

Name

Annotation symbol

CG11380

Feature type

protein_coding_gene

FlyBase ID

FBgn0040359

Gene Model Status

Current

Stock availability

1 publicly available

Also Known As

EG:BACR42I17.7

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

1E4-1E4

Sequence location

X:1,085,444..1,090,705 [+]

Genomic Maps

Select View:

modENCODE GBrowse

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG11380 (FBgn0040359). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1636915_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11380. Gene sequence location is X:1085444..1090705.

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2012_01

Sequence features

HFA18632

BKN45475

BKN32534

FB2011_10

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

1E4-1E4

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG11380 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG11380-RA

FBtr0070201

NM_130535

2710

569

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG11380-PA

FBpp0070194

64.0

569

6.51

NP_569891

AAF45591

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

High-Throughput Expression Data

Untitled Document detailed view

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

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modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010)

mE2_34_mRNA_expression_cluster_07

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0040359

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG11380-RA

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG11380

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG11380^GD6363

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG11380	Class	Mutagen	Stocks	Known lesion
CG11380^G17784		P-element activity	1	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG11380	Class	Mutagen	Stocks	Known lesion
CG11380^GD6363		in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(1)Exel6226

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD6363}

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EP}CG11380^G17784

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Protein-protein

Interacting group

Assay

References

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG11380 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

57628

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0040359

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

31065

Orthologs

Genome-wide drosophilid orthologs

Dana\GF22140

Dere\GG12834

Dgri\GH12002

Dmoj\GI15629

Dper\GL14234

Dpse\GA10962

Dsec\GM19119

Dsim\GD16545

Dvir\GJ15225

Dwil\GK16362

Dyak\GE16668

Curated drosophilid orthologs

Dpse\GA10962

Linkouts

InParanoid A subset of ortholog calls from InParanoid.

•

AAEL000094-PA
Aedes aegypti (mosquito)
AGAP002744-PA
Anopheles gambiae (mosquito)
BGIBMGA008464-PA
Bombyx mori (silk worm)
CPIJ013977
Culex pipens (mosquito)
XP_973563.2
Tribolium castaneum (red flour beetle)

OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.

•

Stocks & Reagents

Stocks Listed in FlyBase ( 1 )

Bloomington

33590

P{EP}CG11380^G17784 w^*

Genomic Clones ( 1 )

BACR10H22

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 40 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

RE11315

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0040359

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

31065

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: EG:BACR42I17.7 CG11380

(FlyBase, 1996-)

Additional comments

Source for merge of EG:BACR42I17.7 CG11380 was sequence comparison (date:000425).

(FlyBase, 1996-)

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_130535

RefSeq (Proteins)

•

NP_569891

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

31065

UniProtKB/TrEMBL

•

Other Crossreferences

Linkouts

BioGRID - A database of protein and genetic interactions

•

57628

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0040359

DRSC - Results from RNAi screens.

•

FBgn0040359

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0040359

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG11380-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0040359

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

31065

InParanoid A subset of ortholog calls from InParanoid.

•

AAEL000094-PA
Aedes aegypti (mosquito)
AGAP002744-PA
Anopheles gambiae (mosquito)
BGIBMGA008464-PA
Bombyx mori (silk worm)
CPIJ013977
Culex pipens (mosquito)
XP_973563.2
Tribolium castaneum (red flour beetle)

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

31065

modMine - Data generated by the modENCODE project.

•

FBgn0040359

OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.

•

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

CG11380

(Lebo et al., 2009)

EG:BACR42I17.7

(Benos et al., 2001, Giot et al., 2003, )

Name Synonym

Secondary FlyBase IDs

FBgn0029566

References ( 12 )

Research paper

Lebo et al., 2009, BMC Genomics 10: 80: Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis. [FBrf0207472]
Benos et al., 2001, Genome Res. 11(5): 710--730: From First Base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. [FBrf0135823]

Supplementary material

The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Bellen, 2010.12.22, GE836.xml: GE836.xml [FBrf0212684]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]
Benos, 2000.12.13, FlyBase error report on Wed Dec 13 14:35:56 2000.: FlyBase error report on Wed Dec 13 14:35:56 2000. [FBrf0133222]

FlyBase analysis

FlyBase, 1996-, FlyBase inference based on genome sequence analysis.: FlyBase inference based on genome sequence analysis. [FBrf0104946]

DNA/RNA sequence record

Benos, 1999.12.28, GenBank/EMBL/DDBJ: AL121806: Drosophila melanogaster BAC clone BACR42I17. [FBrf0141117]

Computer file

BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.: Berkeley Drosophila Genome Project. [FBrf0125078]