This gene is referred to in FlyBase by the symbol Dmel\CG12470 (FBgn0040371). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. The phenotype of this allele is annotated with: trichogen cell. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed during late pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: larval fat body. Comments on Affy2 ProbeSet: ProbeSet 1627679_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG12470. Gene sequence location is X:201717..202975.
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modENCODE Temporal Expression Data for FBgn0040371
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed during late pupal stages, in adult male stages.
[download data (TSV)]
Guide to modENCODE expression level colors
No expression (0 - 0)
Extremely low expression (1 - 10)
Very low expression (11 - 100)
Low expression (101 - 400)
Moderate expression (401 - 1400)
Moderately high expression (1401 - 4000)
High expression (4001 - 10000)
Very high expression (10001 - 100000)
Extremely high expression (100001 - 2000000)
Linear, scaled to maximum FBgn0040371 expression level
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
4
embryo 06-08hr
8
embryo 08-10hr
11
embryo 10-12hr
10
embryo 12-14hr
11
embryo 14-16hr
5
embryo 16-18hr
19
embryo 18-20hr
3
embryo 20-22hr
8
embryo 22-24hr
6
larva L1
3
larva L2
4
larva L3 12hr old
19
larva L3 puffstage 1-2
522
larva L3 puffstage 3-6
1101
larva L3 puffstage 7-9
1697
white prepupae new
1553
white prepupae 12hr
2547
white prepupae 24hr
3453
pupae 2d postWPP
4890
pupae 3d postWPP
4934
pupae 4d postWPP
3225
adult male 01day
8326
adult male 05day
8115
adult male 30day
6726
adult female 01day
7
adult female 05day
1
adult female 30day
4
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Very low expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
4
embryo 06-08hr
8
embryo 08-10hr
11
embryo 10-12hr
10
embryo 12-14hr
11
embryo 14-16hr
5
embryo 16-18hr
19
embryo 18-20hr
3
embryo 20-22hr
8
embryo 22-24hr
6
larva L1
3
larva L2
4
larva L3 12hr old
19
larva L3 puffstage 1-2
(522)
larva L3 puffstage 3-6
(1101)
larva L3 puffstage 7-9
(1697)
white prepupae new
(1553)
white prepupae 12hr
(2547)
white prepupae 24hr
(3453)
pupae 2d postWPP
(4890)
pupae 3d postWPP
(4934)
pupae 4d postWPP
(3225)
adult male 01day
(8326)
adult male 05day
(8115)
adult male 30day
(6726)
adult female 01day
7
adult female 05day
1
adult female 30day
4
Expression Level Scale
None
Extremely low
Very low
Low
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
4
embryo 06-08hr
8
embryo 08-10hr
11
embryo 10-12hr
10
embryo 12-14hr
11
embryo 14-16hr
5
embryo 16-18hr
19
embryo 18-20hr
3
embryo 20-22hr
8
embryo 22-24hr
6
larva L1
3
larva L2
4
larva L3 12hr old
19
larva L3 puffstage 1-2
522
larva L3 puffstage 3-6
1101
larva L3 puffstage 7-9
(1697)
white prepupae new
(1553)
white prepupae 12hr
(2547)
white prepupae 24hr
(3453)
pupae 2d postWPP
(4890)
pupae 3d postWPP
(4934)
pupae 4d postWPP
(3225)
adult male 01day
(8326)
adult male 05day
(8115)
adult male 30day
(6726)
adult female 01day
7
adult female 05day
1
adult female 30day
4
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
4
embryo 06-08hr
8
embryo 08-10hr
11
embryo 10-12hr
10
embryo 12-14hr
11
embryo 14-16hr
5
embryo 16-18hr
19
embryo 18-20hr
3
embryo 20-22hr
8
embryo 22-24hr
6
larva L1
3
larva L2
4
larva L3 12hr old
19
larva L3 puffstage 1-2
522
larva L3 puffstage 3-6
1101
larva L3 puffstage 7-9
1697
white prepupae new
1553
white prepupae 12hr
2547
white prepupae 24hr
3453
pupae 2d postWPP
4890
pupae 3d postWPP
4934
pupae 4d postWPP
3225
adult male 01day
8326
adult male 05day
8115
adult male 30day
6726
adult female 01day
7
adult female 05day
1
adult female 30day
4
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
4
embryo 06-08hr
8
embryo 08-10hr
11
embryo 10-12hr
10
embryo 12-14hr
11
embryo 14-16hr
5
embryo 16-18hr
19
embryo 18-20hr
3
embryo 20-22hr
8
embryo 22-24hr
6
larva L1
3
larva L2
4
larva L3 12hr old
19
larva L3 puffstage 1-2
522
larva L3 puffstage 3-6
1101
larva L3 puffstage 7-9
1697
white prepupae new
1553
white prepupae 12hr
2547
white prepupae 24hr
3453
pupae 2d postWPP
4890
pupae 3d postWPP
4934
pupae 4d postWPP
3225
adult male 01day
8326
adult male 05day
8115
adult male 30day
6726
adult female 01day
7
adult female 05day
1
adult female 30day
4
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to maximum FBgn0040371 expression level
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
4
embryo 06-08hr
8
embryo 08-10hr
11
embryo 10-12hr
10
embryo 12-14hr
11
embryo 14-16hr
5
embryo 16-18hr
19
embryo 18-20hr
3
embryo 20-22hr
8
embryo 22-24hr
6
larva L1
3
larva L2
4
larva L3 12hr old
19
larva L3 puffstage 1-2
522
larva L3 puffstage 3-6
1101
larva L3 puffstage 7-9
1697
white prepupae new
1553
white prepupae 12hr
2547
white prepupae 24hr
3453
pupae 2d postWPP
4890
pupae 3d postWPP
4934
pupae 4d postWPP
3225
adult male 01day
8326
adult male 05day
8115
adult male 30day
6726
adult female 01day
7
adult female 05day
1
adult female 30day
4
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Very low expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
4
embryo 06-08hr
8
embryo 08-10hr
11
embryo 10-12hr
10
embryo 12-14hr
11
embryo 14-16hr
5
embryo 16-18hr
19
embryo 18-20hr
3
embryo 20-22hr
8
embryo 22-24hr
6
larva L1
3
larva L2
4
larva L3 12hr old
19
larva L3 puffstage 1-2
(522)
larva L3 puffstage 3-6
(1101)
larva L3 puffstage 7-9
(1697)
white prepupae new
(1553)
white prepupae 12hr
(2547)
white prepupae 24hr
(3453)
pupae 2d postWPP
(4890)
pupae 3d postWPP
(4934)
pupae 4d postWPP
(3225)
adult male 01day
(8326)
adult male 05day
(8115)
adult male 30day
(6726)
adult female 01day
7
adult female 05day
1
adult female 30day
4
Expression Level Scale
None
Extremely low
Very low
Low
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
4
embryo 06-08hr
8
embryo 08-10hr
11
embryo 10-12hr
10
embryo 12-14hr
11
embryo 14-16hr
5
embryo 16-18hr
19
embryo 18-20hr
3
embryo 20-22hr
8
embryo 22-24hr
6
larva L1
3
larva L2
4
larva L3 12hr old
19
larva L3 puffstage 1-2
522
larva L3 puffstage 3-6
1101
larva L3 puffstage 7-9
1697
white prepupae new
1553
white prepupae 12hr
(2547)
white prepupae 24hr
(3453)
pupae 2d postWPP
(4890)
pupae 3d postWPP
(4934)
pupae 4d postWPP
(3225)
adult male 01day
(8326)
adult male 05day
(8115)
adult male 30day
(6726)
adult female 01day
7
adult female 05day
1
adult female 30day
4
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
4
embryo 06-08hr
8
embryo 08-10hr
11
embryo 10-12hr
10
embryo 12-14hr
11
embryo 14-16hr
5
embryo 16-18hr
19
embryo 18-20hr
3
embryo 20-22hr
8
embryo 22-24hr
6
larva L1
3
larva L2
4
larva L3 12hr old
19
larva L3 puffstage 1-2
522
larva L3 puffstage 3-6
1101
larva L3 puffstage 7-9
1697
white prepupae new
1553
white prepupae 12hr
2547
white prepupae 24hr
3453
pupae 2d postWPP
4890
pupae 3d postWPP
4934
pupae 4d postWPP
3225
adult male 01day
8326
adult male 05day
8115
adult male 30day
6726
adult female 01day
7
adult female 05day
1
adult female 30day
4
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
1
embryo 04-06hr
4
embryo 06-08hr
8
embryo 08-10hr
11
embryo 10-12hr
10
embryo 12-14hr
11
embryo 14-16hr
5
embryo 16-18hr
19
embryo 18-20hr
3
embryo 20-22hr
8
embryo 22-24hr
6
larva L1
3
larva L2
4
larva L3 12hr old
19
larva L3 puffstage 1-2
522
larva L3 puffstage 3-6
1101
larva L3 puffstage 7-9
1697
white prepupae new
1553
white prepupae 12hr
2547
white prepupae 24hr
3453
pupae 2d postWPP
4890
pupae 3d postWPP
4934
pupae 4d postWPP
3225
adult male 01day
8326
adult male 05day
8115
adult male 30day
6726
adult female 01day
7
adult female 05day
1
adult female 30day
4
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
FlyAtlas Anatomical Expression Data for FBgn0040371
Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: larval fat body.
[download data (TSV)]
Guide to FlyAtlas expression level colors
No expression (0 - 9.999)
Low expression (10 - 99.999)
Moderate expression (100 - 499.999)
High level expression (500 - 999.999)
Very high expression (1000 - 25000)
Linear, scaled to maximum FBgn0040371 expression level
Tissue
Expression Level
Larval Central Nervous System
2.95
Larval Midgut
1
Larval Hindgut
0.4
Larval Malpighian Tubules
1.4
Larval Fat Body
261
Larval Salivary Gland
0.6
Larval Trachea
8.15
Larval Carcass
1.55
Adult Head
5.5
Adult Eye
0.925
Adult Brain
5.5
Adult Thoracic-Abdominal Ganglion
5
Adult Crop
1.3
Adult Midgut
0.4
Adult Hindgut
0.7
Adult Malpighian Tubules
2.8
Adult Fat Body
0.8
Adult Salivary Gland
1.2
Adult Heart
no informative data
Adult VirginFemale Spermatheca
2.1
Adult InseminatedFemale Spermatheca
2.5
Adult Ovary
0.4
Adult Testis
1958.6
Adult Male Accessory Gland
5.1
Adult Carcass
5.9
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
2.95
Larval Midgut
1
Larval Hindgut
0.4
Larval Malpighian Tubules
1.4
Larval Fat Body
261
Larval Salivary Gland
0.6
Larval Trachea
8.15
Larval Carcass
1.55
Adult Head
5.5
Adult Eye
0.925
Adult Brain
5.5
Adult Thoracic-Abdominal Ganglion
5
Adult Crop
1.3
Adult Midgut
0.4
Adult Hindgut
0.7
Adult Malpighian Tubules
2.8
Adult Fat Body
0.8
Adult Salivary Gland
1.2
Adult Heart
no informative data
Adult VirginFemale Spermatheca
2.1
Adult InseminatedFemale Spermatheca
2.5
Adult Ovary
0.4
Adult Testis
(1958.6)
Adult Male Accessory Gland
5.1
Adult Carcass
5.9
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
2.95
Larval Midgut
1
Larval Hindgut
0.4
Larval Malpighian Tubules
1.4
Larval Fat Body
261
Larval Salivary Gland
0.6
Larval Trachea
8.15
Larval Carcass
1.55
Adult Head
5.5
Adult Eye
0.925
Adult Brain
5.5
Adult Thoracic-Abdominal Ganglion
5
Adult Crop
1.3
Adult Midgut
0.4
Adult Hindgut
0.7
Adult Malpighian Tubules
2.8
Adult Fat Body
0.8
Adult Salivary Gland
1.2
Adult Heart
no informative data
Adult VirginFemale Spermatheca
2.1
Adult InseminatedFemale Spermatheca
2.5
Adult Ovary
0.4
Adult Testis
(1958.6)
Adult Male Accessory Gland
5.1
Adult Carcass
5.9
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
2.95
Larval Midgut
1
Larval Hindgut
0.4
Larval Malpighian Tubules
1.4
Larval Fat Body
261
Larval Salivary Gland
0.6
Larval Trachea
8.15
Larval Carcass
1.55
Adult Head
5.5
Adult Eye
0.925
Adult Brain
5.5
Adult Thoracic-Abdominal Ganglion
5
Adult Crop
1.3
Adult Midgut
0.4
Adult Hindgut
0.7
Adult Malpighian Tubules
2.8
Adult Fat Body
0.8
Adult Salivary Gland
1.2
Adult Heart
no informative data
Adult VirginFemale Spermatheca
2.1
Adult InseminatedFemale Spermatheca
2.5
Adult Ovary
0.4
Adult Testis
1958.6
Adult Male Accessory Gland
5.1
Adult Carcass
5.9
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to maximum FBgn0040371 expression level
Tissue
Expression Level
Larval Central Nervous System
2.95
Larval Midgut
1
Larval Hindgut
0.4
Larval Malpighian Tubules
1.4
Larval Fat Body
261
Larval Salivary Gland
0.6
Larval Trachea
8.15
Larval Carcass
1.55
Adult Head
5.5
Adult Eye
0.925
Adult Brain
5.5
Adult Thoracic-Abdominal Ganglion
5
Adult Crop
1.3
Adult Midgut
0.4
Adult Hindgut
0.7
Adult Malpighian Tubules
2.8
Adult Fat Body
0.8
Adult Salivary Gland
1.2
Adult Heart
no informative data
Adult VirginFemale Spermatheca
2.1
Adult InseminatedFemale Spermatheca
2.5
Adult Ovary
0.4
Adult Testis
1958.6
Adult Male Accessory Gland
5.1
Adult Carcass
5.9
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
2.95
Larval Midgut
1
Larval Hindgut
0.4
Larval Malpighian Tubules
1.4
Larval Fat Body
261
Larval Salivary Gland
0.6
Larval Trachea
8.15
Larval Carcass
1.55
Adult Head
5.5
Adult Eye
0.925
Adult Brain
5.5
Adult Thoracic-Abdominal Ganglion
5
Adult Crop
1.3
Adult Midgut
0.4
Adult Hindgut
0.7
Adult Malpighian Tubules
2.8
Adult Fat Body
0.8
Adult Salivary Gland
1.2
Adult Heart
no informative data
Adult VirginFemale Spermatheca
2.1
Adult InseminatedFemale Spermatheca
2.5
Adult Ovary
0.4
Adult Testis
(1958.6)
Adult Male Accessory Gland
5.1
Adult Carcass
5.9
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
2.95
Larval Midgut
1
Larval Hindgut
0.4
Larval Malpighian Tubules
1.4
Larval Fat Body
261
Larval Salivary Gland
0.6
Larval Trachea
8.15
Larval Carcass
1.55
Adult Head
5.5
Adult Eye
0.925
Adult Brain
5.5
Adult Thoracic-Abdominal Ganglion
5
Adult Crop
1.3
Adult Midgut
0.4
Adult Hindgut
0.7
Adult Malpighian Tubules
2.8
Adult Fat Body
0.8
Adult Salivary Gland
1.2
Adult Heart
no informative data
Adult VirginFemale Spermatheca
2.1
Adult InseminatedFemale Spermatheca
2.5
Adult Ovary
0.4
Adult Testis
(1958.6)
Adult Male Accessory Gland
5.1
Adult Carcass
5.9
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
2.95
Larval Midgut
1
Larval Hindgut
0.4
Larval Malpighian Tubules
1.4
Larval Fat Body
261
Larval Salivary Gland
0.6
Larval Trachea
8.15
Larval Carcass
1.55
Adult Head
5.5
Adult Eye
0.925
Adult Brain
5.5
Adult Thoracic-Abdominal Ganglion
5
Adult Crop
1.3
Adult Midgut
0.4
Adult Hindgut
0.7
Adult Malpighian Tubules
2.8
Adult Fat Body
0.8
Adult Salivary Gland
1.2
Adult Heart
no informative data
Adult VirginFemale Spermatheca
2.1
Adult InseminatedFemale Spermatheca
2.5
Adult Ovary
0.4
Adult Testis
1958.6
Adult Male Accessory Gland
5.1
Adult Carcass
5.9
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
no informative data
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 16 )
Please Note
This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see GBrowse for alignment of the cDNAs and ESTs
to the gene model.
Wake-up-call, a lin-52 paralogue, and Always early, a lin-9 homologue physically interact, but have opposing functions in regulating testis-specific gene expression. [FBrf0213964]
Sousa-Neves and Rosas, 2010, PLoS ONE 5(5): e10485
An analysis of genetic changes during the divergence of Drosophila species. [FBrf0210766]
Stuart et al., 2007, Nature 445(7123): 95--101
A systems biology analysis of the Drosophila phagosome. [FBrf0195342]
Liu et al., 2005, Nature Genetics 37(12): 1361--1366
Sex-specific role of Drosophila melanogaster HP1 in regulating chromatin structure and gene transcription. [FBrf0191273]
Benos et al., 2001, Genome Res. 11(5): 710--730
From First Base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. [FBrf0135823]
Supplementary material
Wasbrough et al., 2010, J. Proteomics 73(11):
Supplemental Table 1. Mass spectrometry data. [FBrf0213252]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center
RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348).
File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
Bayraktaroglu, 2000.8.7, Matches of the nc3 class to CGs.