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Gene Dmel\CG14629

General Information
Symbol	Dmel\CG14629	Species	D. melanogaster
Name		Annotation symbol	CG14629
Feature type	protein_coding_gene	FlyBase ID	FBgn0040398
Gene Model Status	Current	Stock availability	2 publicly available
Also Known As	EG:103E12.2
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	1E1-1E1	Sequence location	X:945,557..946,664 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG14629 (FBgn0040398). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein of unknown function DUF1397. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult midgut, larval Malpighian tubules, adult heart, larval/adult fat body, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult brain, larval/adult hindgut, adult Malpighian tubules, larval trachea, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1636804_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG14629. Gene sequence location is X:945557..946664.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	References Meiklejohn et al., 2011, PLoS Biol. 9(8): e1001126
FB2012_01	Sequence features BKN31296 HFA18476
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 1E1-1E1   Limits computationally determined from genome sequence between P{EP}EP1600&P{EP}EP1498 and P{EP}EP1615&P{EP}EP964
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG14629 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG14629-RA FBtr0070179  NM_130525   1108   319
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG14629-PA   FBpp0070172   35.0   319   5.04     NP_569881   AAF45581
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein of unknown function DUF1397 (IPR009832)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF45581   AI062573   AI063621   AI107744   AI113475   AI133917   AI134272   AI257766   AI257923   AI259125   AI297269   AI388088   AI388251   AI405062   AI514006   AL132651 CAB59576   AW940715   AY060737 AAL28285   BG637406   BG639365   BI163568   BI164009   BI164551   BI169315   BI173676   BI214840   BI214999   BI216392   BI228895   BI234953   BI237769   BI355971   BI358330   BI361437   BI362779   BI367027   BI368330   BI375726   BI484714   BI564917   BI569929   BI569974   BI570044   BI579254   BI580051   BI580436   BI584315   BI590285   BI590293   BI606068   BI606102   BI609389   BI609999   BI612052   BI612593   BI614916   BI616434   BI616965   BI620704   BI629397   BI631743   BI636121   BI639328   CK445240   CK658167   CO153050   CO177161   CO182458   CO191504   CO194380   EC074796   EC241517   EC265049   EC267240   EL879803   EV591732
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9NF33 Q9W5B4
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0040398    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0040398 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0040398 expression level Developmental Stage   Expression Level embryo 00-02hr    153 embryo 02-04hr    353 embryo 04-06hr    564 embryo 06-08hr    6490 embryo 08-10hr    13724 embryo 10-12hr    29676 embryo 12-14hr    26486 embryo 14-16hr    36198 embryo 16-18hr    24014 embryo 18-20hr    13158 embryo 20-22hr    4884 embryo 22-24hr    4671 larva L1    8407 larva L2    12287 larva L3 12hr old    20643 larva L3 puffstage 1-2    22148 larva L3 puffstage 3-6    23234 larva L3 puffstage 7-9    17268 white prepupae new    21530 white prepupae 12hr    23473 white prepupae 24hr    25786 pupae 2d postWPP    19176 pupae 3d postWPP    14326 pupae 4d postWPP    7189 adult male 01day    13357 adult male 05day    16563 adult male 30day    11882 adult female 01day    9157 adult female 05day    8560 adult female 30day    11860 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (153) embryo 02-04hr  (353) embryo 04-06hr  (564) embryo 06-08hr  (6490) embryo 08-10hr  (13724) embryo 10-12hr  (29676) embryo 12-14hr  (26486) embryo 14-16hr  (36198) embryo 16-18hr  (24014) embryo 18-20hr  (13158) embryo 20-22hr  (4884) embryo 22-24hr  (4671) larva L1  (8407) larva L2  (12287) larva L3 12hr old  (20643) larva L3 puffstage 1-2  (22148) larva L3 puffstage 3-6  (23234) larva L3 puffstage 7-9  (17268) white prepupae new  (21530) white prepupae 12hr  (23473) white prepupae 24hr  (25786) pupae 2d postWPP  (19176) pupae 3d postWPP  (14326) pupae 4d postWPP  (7189) adult male 01day  (13357) adult male 05day  (16563) adult male 30day  (11882) adult female 01day  (9157) adult female 05day  (8560) adult female 30day  (11860) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    153 embryo 02-04hr    353 embryo 04-06hr    564 embryo 06-08hr  (6490) embryo 08-10hr  (13724) embryo 10-12hr  (29676) embryo 12-14hr  (26486) embryo 14-16hr  (36198) embryo 16-18hr  (24014) embryo 18-20hr  (13158) embryo 20-22hr  (4884) embryo 22-24hr  (4671) larva L1  (8407) larva L2  (12287) larva L3 12hr old  (20643) larva L3 puffstage 1-2  (22148) larva L3 puffstage 3-6  (23234) larva L3 puffstage 7-9  (17268) white prepupae new  (21530) white prepupae 12hr  (23473) white prepupae 24hr  (25786) pupae 2d postWPP  (19176) pupae 3d postWPP  (14326) pupae 4d postWPP  (7189) adult male 01day  (13357) adult male 05day  (16563) adult male 30day  (11882) adult female 01day  (9157) adult female 05day  (8560) adult female 30day  (11860) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    153 embryo 02-04hr    353 embryo 04-06hr    564 embryo 06-08hr    6490 embryo 08-10hr  (13724) embryo 10-12hr  (29676) embryo 12-14hr  (26486) embryo 14-16hr  (36198) embryo 16-18hr  (24014) embryo 18-20hr  (13158) embryo 20-22hr    4884 embryo 22-24hr    4671 larva L1    8407 larva L2  (12287) larva L3 12hr old  (20643) larva L3 puffstage 1-2  (22148) larva L3 puffstage 3-6  (23234) larva L3 puffstage 7-9  (17268) white prepupae new  (21530) white prepupae 12hr  (23473) white prepupae 24hr  (25786) pupae 2d postWPP  (19176) pupae 3d postWPP  (14326) pupae 4d postWPP    7189 adult male 01day  (13357) adult male 05day  (16563) adult male 30day  (11882) adult female 01day    9157 adult female 05day    8560 adult female 30day  (11860) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    153 embryo 02-04hr    353 embryo 04-06hr    564 embryo 06-08hr    6490 embryo 08-10hr    13724 embryo 10-12hr    29676 embryo 12-14hr    26486 embryo 14-16hr    36198 embryo 16-18hr    24014 embryo 18-20hr    13158 embryo 20-22hr    4884 embryo 22-24hr    4671 larva L1    8407 larva L2    12287 larva L3 12hr old    20643 larva L3 puffstage 1-2    22148 larva L3 puffstage 3-6    23234 larva L3 puffstage 7-9    17268 white prepupae new    21530 white prepupae 12hr    23473 white prepupae 24hr    25786 pupae 2d postWPP    19176 pupae 3d postWPP    14326 pupae 4d postWPP    7189 adult male 01day    13357 adult male 05day    16563 adult male 30day    11882 adult female 01day    9157 adult female 05day    8560 adult female 30day    11860 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0040398 expression level Developmental Stage   Expression Level embryo 00-02hr    153 embryo 02-04hr    353 embryo 04-06hr    564 embryo 06-08hr    6490 embryo 08-10hr    13724 embryo 10-12hr    29676 embryo 12-14hr    26486 embryo 14-16hr    36198 embryo 16-18hr    24014 embryo 18-20hr    13158 embryo 20-22hr    4884 embryo 22-24hr    4671 larva L1    8407 larva L2    12287 larva L3 12hr old    20643 larva L3 puffstage 1-2    22148 larva L3 puffstage 3-6    23234 larva L3 puffstage 7-9    17268 white prepupae new    21530 white prepupae 12hr    23473 white prepupae 24hr    25786 pupae 2d postWPP    19176 pupae 3d postWPP    14326 pupae 4d postWPP    7189 adult male 01day    13357 adult male 05day    16563 adult male 30day    11882 adult female 01day    9157 adult female 05day    8560 adult female 30day    11860 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (153) embryo 02-04hr  (353) embryo 04-06hr  (564) embryo 06-08hr  (6490) embryo 08-10hr  (13724) embryo 10-12hr  (29676) embryo 12-14hr  (26486) embryo 14-16hr  (36198) embryo 16-18hr  (24014) embryo 18-20hr  (13158) embryo 20-22hr  (4884) embryo 22-24hr  (4671) larva L1  (8407) larva L2  (12287) larva L3 12hr old  (20643) larva L3 puffstage 1-2  (22148) larva L3 puffstage 3-6  (23234) larva L3 puffstage 7-9  (17268) white prepupae new  (21530) white prepupae 12hr  (23473) white prepupae 24hr  (25786) pupae 2d postWPP  (19176) pupae 3d postWPP  (14326) pupae 4d postWPP  (7189) adult male 01day  (13357) adult male 05day  (16563) adult male 30day  (11882) adult female 01day  (9157) adult female 05day  (8560) adult female 30day  (11860) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    153 embryo 02-04hr    353 embryo 04-06hr    564 embryo 06-08hr  (6490) embryo 08-10hr  (13724) embryo 10-12hr  (29676) embryo 12-14hr  (26486) embryo 14-16hr  (36198) embryo 16-18hr  (24014) embryo 18-20hr  (13158) embryo 20-22hr  (4884) embryo 22-24hr  (4671) larva L1  (8407) larva L2  (12287) larva L3 12hr old  (20643) larva L3 puffstage 1-2  (22148) larva L3 puffstage 3-6  (23234) larva L3 puffstage 7-9  (17268) white prepupae new  (21530) white prepupae 12hr  (23473) white prepupae 24hr  (25786) pupae 2d postWPP  (19176) pupae 3d postWPP  (14326) pupae 4d postWPP  (7189) adult male 01day  (13357) adult male 05day  (16563) adult male 30day  (11882) adult female 01day  (9157) adult female 05day  (8560) adult female 30day  (11860) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    153 embryo 02-04hr    353 embryo 04-06hr    564 embryo 06-08hr    6490 embryo 08-10hr  13724 embryo 10-12hr  (29676) embryo 12-14hr  (26486) embryo 14-16hr  (36198) embryo 16-18hr  (24014) embryo 18-20hr  13158 embryo 20-22hr    4884 embryo 22-24hr    4671 larva L1    8407 larva L2  12287 larva L3 12hr old  (20643) larva L3 puffstage 1-2  (22148) larva L3 puffstage 3-6  (23234) larva L3 puffstage 7-9  17268 white prepupae new  (21530) white prepupae 12hr  (23473) white prepupae 24hr  (25786) pupae 2d postWPP  19176 pupae 3d postWPP  14326 pupae 4d postWPP    7189 adult male 01day  13357 adult male 05day  16563 adult male 30day  11882 adult female 01day    9157 adult female 05day    8560 adult female 30day  11860 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    153 embryo 02-04hr    353 embryo 04-06hr    564 embryo 06-08hr    6490 embryo 08-10hr    13724 embryo 10-12hr    29676 embryo 12-14hr    26486 embryo 14-16hr    36198 embryo 16-18hr    24014 embryo 18-20hr    13158 embryo 20-22hr    4884 embryo 22-24hr    4671 larva L1    8407 larva L2    12287 larva L3 12hr old    20643 larva L3 puffstage 1-2    22148 larva L3 puffstage 3-6    23234 larva L3 puffstage 7-9    17268 white prepupae new    21530 white prepupae 12hr    23473 white prepupae 24hr    25786 pupae 2d postWPP    19176 pupae 3d postWPP    14326 pupae 4d postWPP    7189 adult male 01day    13357 adult male 05day    16563 adult male 30day    11882 adult female 01day    9157 adult female 05day    8560 adult female 30day    11860 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0040398    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0040398 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult midgut, larval Malpighian tubules, adult heart, larval/adult fat body, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult brain, larval/adult hindgut, adult Malpighian tubules, larval trachea, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0040398 expression level Tissue   Expression Level Larval Central Nervous System    2.8 Larval Midgut    777.8 Larval Hindgut    147.2 Larval Malpighian Tubules    1077.8 Larval Fat Body    5598.5 Larval Salivary Gland    86.5 Larval Trachea    116.875 Larval Carcass    248 Adult Head    2135.8 Adult Eye    862.75 Adult Brain    122.3 Adult Thoracic-Abdominal Ganglion    71.6 Adult Crop    50 Adult Midgut    746.3 Adult Hindgut    193.4 Adult Malpighian Tubules    195 Adult Fat Body    3291.7 Adult Salivary Gland no informative data Adult Heart    2672.475 Adult VirginFemale Spermatheca    1431.1 Adult InseminatedFemale Spermatheca    1327.7 Adult Ovary    7.8 Adult Testis no informative data Adult Male Accessory Gland    5.6 Adult Carcass    2242.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.8 Larval Midgut  (777.8) Larval Hindgut    147.2 Larval Malpighian Tubules  (1077.8) Larval Fat Body  (5598.5) Larval Salivary Gland    86.5 Larval Trachea    116.875 Larval Carcass    248 Adult Head  (2135.8) Adult Eye  (862.75) Adult Brain    122.3 Adult Thoracic-Abdominal Ganglion    71.6 Adult Crop    50 Adult Midgut  (746.3) Adult Hindgut    193.4 Adult Malpighian Tubules    195 Adult Fat Body  (3291.7) Adult Salivary Gland no informative data Adult Heart  (2672.475) Adult VirginFemale Spermatheca  (1431.1) Adult InseminatedFemale Spermatheca  (1327.7) Adult Ovary    7.8 Adult Testis no informative data Adult Male Accessory Gland    5.6 Adult Carcass  (2242.6) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.8 Larval Midgut    777.8 Larval Hindgut    147.2 Larval Malpighian Tubules  1077.8 Larval Fat Body  (5598.5) Larval Salivary Gland    86.5 Larval Trachea    116.875 Larval Carcass    248 Adult Head  (2135.8) Adult Eye    862.75 Adult Brain    122.3 Adult Thoracic-Abdominal Ganglion    71.6 Adult Crop    50 Adult Midgut    746.3 Adult Hindgut    193.4 Adult Malpighian Tubules    195 Adult Fat Body  (3291.7) Adult Salivary Gland no informative data Adult Heart  (2672.475) Adult VirginFemale Spermatheca  (1431.1) Adult InseminatedFemale Spermatheca  (1327.7) Adult Ovary    7.8 Adult Testis no informative data Adult Male Accessory Gland    5.6 Adult Carcass  (2242.6) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.8 Larval Midgut    777.8 Larval Hindgut    147.2 Larval Malpighian Tubules    1077.8 Larval Fat Body    5598.5 Larval Salivary Gland    86.5 Larval Trachea    116.875 Larval Carcass    248 Adult Head    2135.8 Adult Eye    862.75 Adult Brain    122.3 Adult Thoracic-Abdominal Ganglion    71.6 Adult Crop    50 Adult Midgut    746.3 Adult Hindgut    193.4 Adult Malpighian Tubules    195 Adult Fat Body    3291.7 Adult Salivary Gland no informative data Adult Heart    2672.475 Adult VirginFemale Spermatheca    1431.1 Adult InseminatedFemale Spermatheca    1327.7 Adult Ovary    7.8 Adult Testis no informative data Adult Male Accessory Gland    5.6 Adult Carcass    2242.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0040398 expression level Tissue   Expression Level Larval Central Nervous System    2.8 Larval Midgut    777.8 Larval Hindgut    147.2 Larval Malpighian Tubules    1077.8 Larval Fat Body    5598.5 Larval Salivary Gland    86.5 Larval Trachea    116.875 Larval Carcass    248 Adult Head    2135.8 Adult Eye    862.75 Adult Brain    122.3 Adult Thoracic-Abdominal Ganglion    71.6 Adult Crop    50 Adult Midgut    746.3 Adult Hindgut    193.4 Adult Malpighian Tubules    195 Adult Fat Body    3291.7 Adult Salivary Gland no informative data Adult Heart    2672.475 Adult VirginFemale Spermatheca    1431.1 Adult InseminatedFemale Spermatheca    1327.7 Adult Ovary    7.8 Adult Testis no informative data Adult Male Accessory Gland    5.6 Adult Carcass    2242.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.8 Larval Midgut  777.8 Larval Hindgut    147.2 Larval Malpighian Tubules  (1077.8) Larval Fat Body  (5598.5) Larval Salivary Gland    86.5 Larval Trachea    116.875 Larval Carcass    248 Adult Head  (2135.8) Adult Eye  (862.75) Adult Brain    122.3 Adult Thoracic-Abdominal Ganglion    71.6 Adult Crop    50 Adult Midgut  746.3 Adult Hindgut    193.4 Adult Malpighian Tubules    195 Adult Fat Body  (3291.7) Adult Salivary Gland no informative data Adult Heart  (2672.475) Adult VirginFemale Spermatheca  (1431.1) Adult InseminatedFemale Spermatheca  (1327.7) Adult Ovary    7.8 Adult Testis no informative data Adult Male Accessory Gland    5.6 Adult Carcass  (2242.6) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.8 Larval Midgut    777.8 Larval Hindgut    147.2 Larval Malpighian Tubules  1077.8 Larval Fat Body  (5598.5) Larval Salivary Gland    86.5 Larval Trachea    116.875 Larval Carcass    248 Adult Head  (2135.8) Adult Eye    862.75 Adult Brain    122.3 Adult Thoracic-Abdominal Ganglion    71.6 Adult Crop    50 Adult Midgut    746.3 Adult Hindgut    193.4 Adult Malpighian Tubules    195 Adult Fat Body  (3291.7) Adult Salivary Gland no informative data Adult Heart  (2672.475) Adult VirginFemale Spermatheca  1431.1 Adult InseminatedFemale Spermatheca  1327.7 Adult Ovary    7.8 Adult Testis no informative data Adult Male Accessory Gland    5.6 Adult Carcass  (2242.6) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.8 Larval Midgut    777.8 Larval Hindgut    147.2 Larval Malpighian Tubules    1077.8 Larval Fat Body    5598.5 Larval Salivary Gland    86.5 Larval Trachea    116.875 Larval Carcass    248 Adult Head    2135.8 Adult Eye    862.75 Adult Brain    122.3 Adult Thoracic-Abdominal Ganglion    71.6 Adult Crop    50 Adult Midgut    746.3 Adult Hindgut    193.4 Adult Malpighian Tubules    195 Adult Fat Body    3291.7 Adult Salivary Gland no informative data Adult Heart    2672.475 Adult VirginFemale Spermatheca    1431.1 Adult InseminatedFemale Spermatheca    1327.7 Adult Ovary    7.8 Adult Testis no informative data Adult Male Accessory Gland    5.6 Adult Carcass    2242.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis no informative data Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    2135.8   NA  Eye    862.75   NA  Brain    122.3   2.8  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    71.6   NA  Crop    50   777.8  Midgut    746.3   147.2  Hindgut    193.4   1077.8  Malpighian Tubules    195   5598.5  Fat Body    3291.7   86.5  Salivary Gland    no informative data   NA  Heart    2672.475   116.875  Trachea    NA   NA  VirginFemale Spermatheca    1431.1   NA  InseminatedFemale Spermatheca    1327.7   NA  Ovary    7.8   NA  Testis    no informative data   NA  Male Accessory Gland    5.6   248  Carcass    2242.6 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_25
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040398 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14629-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG14629 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG14629 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG14629 Class Mutagen Stocks Known lesion CG14629GD6360 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG14629KK111296 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6225 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6360} NA P{KK111296} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG14629 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 57619 DroID - A comprehensive database of gene and protein interactions. • FBgn0040398 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31055
Orthologs
Genome-wide drosophilid orthologs	Dana\GF22129 Dere\GG12829 Dgri\GH11994 Dmoj\GI15617 Dper\GL14224 Dpse\GA13127 Dsec\GM19113 Dsim\GD16543 Dvir\GJ15221 Dwil\GK16357 Dyak\GE16661
Curated drosophilid orthologs	Dpse\GA13127   Dsim\CG14629 (Landry et al., 2005)
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • BGIBMGA000462-PA Bombyx mori (silk worm) PHUM008099-PA Pediculus humanus (human body louse) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB11599 NV16265 LH14334 FBgn0234160 FBgn0234158 FBgn0233534 FBgn0218362 FBgn0218359 FBgn0212081 FBgn0206585 FBgn0203520 FBgn0202417 FBgn0188149 FBgn0188148 FBgn0187417 FBgn0174017 FBgn0174015 FBgn0168340 JGI_V11_308930 FBgn0082101 FBgn0073165 FBgn0071015 FBgn0158937 FBgn0151834 FBgn0151829 FBgn0138373 FBgn0138366 FBgn0133740 FBgn0040364 FBgn0030740 FBgn0119758 FBgn0119476 FBgn0119473 FBgn0111535 FBgn0105106 FBgn0105105 FBgn0099133 FBgn0099134 FBgn0099128 FBgn0096094 CPIJ000194 CPIJ000195 BGIBMGA000462 BGIBMGA000233 ACYPI002184 GB16008 GB11627 AGAP007665 AGAP007663 AAEL008485 AAEL008478 AAEL002109 PHUM262670 GLEAN_12520 GLEAN_12519 GLEAN_11877
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v107496 P{KK111296}VIE-260B v51648 w1118; P{GD6360}v51648/CyO
Genomic Clones ( 1 )
	BACR29P19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 72 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH18858
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH01809 GH03538 GH05579 GH09794 GH10968 GH11684 GH19080 GH24974 GH27046 LP02465 LP06211 LP06231 LP06426 LP11536 LP14231 LP14817 RE02993 RE03564 RE04250 RE10452 RE16748 RE20973 RE21177 RE23517 RE26553 RE30732 RE34060 RE37042 RE45071 RE45648 RE47437 RE52694 RE54281 RE63592 RE67856 RE73252 RE74173 RE74630 RH02133 RH02186 RH02281 RH03881 RH03890 RH14162 RH14860 RH23462 RH40428 RH41521 RH44416 RH46382 RH47151 RH51903 RH58257 RH61381 RH62518 RH72150 RH72195 SD15407 SD17692 SD21886
Other clones	66127 522005 557026 CK01.66C.E12 Dmel_neb_014620_0327_2005 EC22725 EC31206 EC38406 EK052650 EN01152 IP09715
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0040398 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31055
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: EG:103E12.2 CG14629 (FlyBase, 1996-)
Additional comments	Source for merge of EG:103E12.2 CG14629 was sequence comparison (date:000425). (FlyBase, 1996-)
Other Comments
	CG14629 encodes a putative helical cytokine. (Cheng et al., 2009)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_130525 RefSeq (Proteins) • NP_569881 DDBJ / EMBL / GenBank • AAF45581 AAL28285 AI388088 AI405062 AL132651 AW940715 AY060737 CAB59576 Entrez Gene - A searchable database of RefSeq genes. • 31055 UniProtKB/TrEMBL • Q9NF33 Q9W5B4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein of unknown function DUF1397 (IPR009832)
Linkouts
	BioGRID - A database of protein and genetic interactions • 57619 DroID - A comprehensive database of gene and protein interactions. • FBgn0040398 DRSC - Results from RNAi screens. • FBgn0040398 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040398 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14629-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0040398 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31055 InParanoid A subset of ortholog calls from InParanoid. • BGIBMGA000462-PA Bombyx mori (silk worm) PHUM008099-PA Pediculus humanus (human body louse) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31055 modMine - Data generated by the modENCODE project. • FBgn0040398 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB11599 NV16265 LH14334 FBgn0234160 FBgn0234158 FBgn0233534 FBgn0218362 FBgn0218359 FBgn0212081 FBgn0206585 FBgn0203520 FBgn0202417 FBgn0188149 FBgn0188148 FBgn0187417 FBgn0174017 FBgn0174015 FBgn0168340 JGI_V11_308930 FBgn0082101 FBgn0073165 FBgn0071015 FBgn0158937 FBgn0151834 FBgn0151829 FBgn0138373 FBgn0138366 FBgn0133740 FBgn0040364 FBgn0030740 FBgn0119758 FBgn0119476 FBgn0119473 FBgn0111535 FBgn0105106 FBgn0105105 FBgn0099133 FBgn0099134 FBgn0099128 FBgn0096094 CPIJ000194 CPIJ000195 BGIBMGA000462 BGIBMGA000233 ACYPI002184 GB16008 GB11627 AGAP007665 AGAP007663 AAEL008485 AAEL008478 AAEL002109 PHUM262670 GLEAN_12520 GLEAN_12519 GLEAN_11877
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG14629 (Isogai et al., 2007, Roxstrom-Lindquist et al., 2004, Keleman et al., 2009.8.5, Wittkopp et al., 2008, Juhasz et al., 2007, Cheng et al., 2009, Meiklejohn et al., 2011) EG:103E12.2 (Benos, 1999.12.13, Benos et al., 2001, Adryan et al., 2007)
Name Synonym
Secondary FlyBase IDs
	FBgn0029556
References ( 19 )
Research paper	Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784 GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834] Meiklejohn et al., 2011, PLoS Biol. 9(8): e1001126 Sex Chromosome-Specific Regulation in the Drosophila Male Germline But Little Evidence for Chromosomal Dosage Compensation or Meiotic Inactivation. [FBrf0214756] Cheng et al., 2009, J. Interferon Cytokine Res. 29(8): 461--468 Identification of a putative invertebrate helical cytokine similar to the ciliary neurotrophic factor/leukemia inhibitory factor family by PSI-BLAST-based approach. [FBrf0208413] Adryan et al., 2007, Genome Biol. 8(8): R167 Genomic mapping of Suppressor of Hairy-wing binding sites in Drosophila. [FBrf0205349] Isogai et al., 2007, Genes Dev. 21(22): 2936--2949 Transcription of histone gene cluster by differential core-promoter factors. [FBrf0202929] Juhasz et al., 2007, Cell Death Diffn: Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophila fat body. [FBrf0194904] Landry et al., 2005, Genetics 171(4): 1813--1822 Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of Drosophila. [FBrf0190735] Roxstrom-Lindquist et al., 2004, EMBO Rpts 5(2): 207--212 Parasite-specific immune response in adult Drosophila melanogaster: a genomic study. [FBrf0167559] Vierstraete et al., 2003, Biochem. biophys. Res. Commun. 304(4): 831--838 Proteomics in Drosophila melanogaster: first 2D database of larval hemolymph proteins. [FBrf0158736] Benos et al., 2001, Genome Res. 11(5): 710--730 From First Base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. [FBrf0135823]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Wittkopp et al., 2008, Nat. Genet. 40(3): Supplementary Information [FBrf0208881]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Benos, 2000.12.13, FlyBase error report on Wed Dec 13 14:35:56 2000. FlyBase error report on Wed Dec 13 14:35:56 2000. [FBrf0133222]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]
DNA/RNA sequence record	Benos, 1999.12.13, GenBank/EMBL/DDBJ: AL132651 Drosophila melanogaster cosmid clone 103E12. [FBrf0141118]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]