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Gene Dmel\grsm

General Information
Symbol	Dmel\grsm	Species	D. melanogaster
Name	granny smith	Annotation symbol	CG7340
Feature type	protein_coding_gene	FlyBase ID	FBgn0040493
Gene Model Status	Current	Stock availability	11 publicly available
Also Known As	BcDNA:LD41548, granny-smith
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	87D5-87D5	Sequence location	3R:8,775,764..8,793,434 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene granny smith is referred to in FlyBase by the symbol Dmel\grsm (CG7340, FBgn0040493). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: aminopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: proteolysis. 13 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Leucine aminopeptidase/peptidase B; Peptidase M17, leucyl aminopeptidase, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed during late larval stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval midgut, larval hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval salivary gland, larval trachea, adult ovary, adult testis, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, adult hindgut, adult fat body, adult salivary gland, adult spermathecae, adult male accessory gland, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1636125_a_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of granny-smith. Gene sequence location is 3R:8775764..8793434.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 87D5-87D5   Limits computationally determined from genome sequence between P{lacW}Vha55j2E9 and P{PZ}CtBP03463
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\grsm for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.48 Low-frequency RNA-Seq exon junction(s) not annotated. DGC clone LD13869 appears problematic: incomplete CDS
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) grsm-RB FBtr0082730  NM_141983   1957   558 grsm-RD FBtr0290273  NM_169482   2234   533
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein grsm-PB   FBpp0082198   60.2   558   6.77     NP_650240   AAF54873 grsm-PD   FBpp0288712   57.2   533   6.16     NP_731749   AAF54874
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Peptidase M17, leucyl aminopeptidase, C-terminal (IPR000819) Leucine aminopeptidase/peptidase B (IPR011356)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA439330   AA802289   AA803358   AA804092   AA820312   AA942361   AA990679   AE014297 AAF54873   AE014297 AAF54874   AF218811 AAF32328   AF218812 AAF32329   AI455389   AI515859   AI517383   AI533034   AI544267   AI946765   AW942289   BE977906   BE978006   BF485966   BF485978   BF487530   BF487714   BF488232   BF488536   BF489419   BF489909   BF491667   BF492494   BF492495   BF495677   BF497453   BF497485   BF498219   BF499581   BF501245   BF501775   BF502159   BF502316   BF504028   BF505851   BG633710   BG633814   BG633817   BG634100   BG634211   BG634963   BG635052   BG635127   BG640898   BI241882   BI243520   BI367279   BI635091   BT001371 AAN71126   BT100045   CK658447   CK660845   CK660868   CK662306   CL528046   CO188230   CO189691   CO279140   CO282402   CO291507   CO307571   CO308407   CO321225   CO321754   CO328158   CZ466173   CZ467957   CZ482194   CZ483524   EC051626   EC054615   EC056410   EC069395   EC077682   EC223299   EC244542   EC246901   EC257734   EL873474   EL873475   GH755290   GH758034   GH775493   GH777846   GH779981   GH780174   GH780902   GH785162   GH791467   GH791798   GH793860   GH806433   GH807764   GH812511   GH821911   GH832273   GH834707   GH844181   GH846480   GH847997   GH861340   GH862567   GH862772   GH864064   GH870481   GH882004   GH895583   GH897960   GH902316   GH916879   GH918418   GH918781   GH919040   GH919195   GH929158   GH930917
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9V3D8 Q9VG16 Q8IH82 Q9NHV8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval midgut, larval hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval salivary gland, larval trachea, adult ovary, adult testis, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, adult hindgut, adult fat body, adult salivary gland, adult spermathecae, adult male accessory gland, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    446.625 Larval Midgut    789.7 Larval Hindgut    681.2 Larval Malpighian Tubules    3020.1 Larval Fat Body    1540.8 Larval Salivary Gland    1107.8 Larval Trachea    822.325 Larval Carcass    1706.1 Adult Head    247.7 Adult Eye    185.775 Adult Brain    154.9 Adult Thoracic-Abdominal Ganglion    164.7 Adult Crop    281.1 Adult Midgut    488.5 Adult Hindgut    239.8 Adult Malpighian Tubules    1000.5 Adult Fat Body    496.6 Adult Salivary Gland    226.8 Adult Heart    974.575 Adult VirginFemale Spermatheca    445 Adult InseminatedFemale Spermatheca    403 Adult Ovary    758.8 Adult Testis    1273.2 Adult Male Accessory Gland    366.2 Adult Carcass    389.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    446.625 Larval Midgut  (789.7) Larval Hindgut  (681.2) Larval Malpighian Tubules  (3020.1) Larval Fat Body  (1540.8) Larval Salivary Gland  (1107.8) Larval Trachea  (822.325) Larval Carcass  (1706.1) Adult Head    247.7 Adult Eye    185.775 Adult Brain    154.9 Adult Thoracic-Abdominal Ganglion    164.7 Adult Crop    281.1 Adult Midgut    488.5 Adult Hindgut    239.8 Adult Malpighian Tubules  (1000.5) Adult Fat Body    496.6 Adult Salivary Gland    226.8 Adult Heart  (974.575) Adult VirginFemale Spermatheca    445 Adult InseminatedFemale Spermatheca    403 Adult Ovary  (758.8) Adult Testis  (1273.2) Adult Male Accessory Gland    366.2 Adult Carcass    389.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    446.625 Larval Midgut    789.7 Larval Hindgut    681.2 Larval Malpighian Tubules  (3020.1) Larval Fat Body  (1540.8) Larval Salivary Gland  (1107.8) Larval Trachea    822.325 Larval Carcass  (1706.1) Adult Head    247.7 Adult Eye    185.775 Adult Brain    154.9 Adult Thoracic-Abdominal Ganglion    164.7 Adult Crop    281.1 Adult Midgut    488.5 Adult Hindgut    239.8 Adult Malpighian Tubules  1000.5 Adult Fat Body    496.6 Adult Salivary Gland    226.8 Adult Heart    974.575 Adult VirginFemale Spermatheca    445 Adult InseminatedFemale Spermatheca    403 Adult Ovary    758.8 Adult Testis  (1273.2) Adult Male Accessory Gland    366.2 Adult Carcass    389.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    446.625 Larval Midgut    789.7 Larval Hindgut    681.2 Larval Malpighian Tubules    3020.1 Larval Fat Body    1540.8 Larval Salivary Gland    1107.8 Larval Trachea    822.325 Larval Carcass    1706.1 Adult Head    247.7 Adult Eye    185.775 Adult Brain    154.9 Adult Thoracic-Abdominal Ganglion    164.7 Adult Crop    281.1 Adult Midgut    488.5 Adult Hindgut    239.8 Adult Malpighian Tubules    1000.5 Adult Fat Body    496.6 Adult Salivary Gland    226.8 Adult Heart    974.575 Adult VirginFemale Spermatheca    445 Adult InseminatedFemale Spermatheca    403 Adult Ovary    758.8 Adult Testis    1273.2 Adult Male Accessory Gland    366.2 Adult Carcass    389.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    446.625 Larval Midgut    789.7 Larval Hindgut    681.2 Larval Malpighian Tubules    3020.1 Larval Fat Body    1540.8 Larval Salivary Gland    1107.8 Larval Trachea    822.325 Larval Carcass    1706.1 Adult Head    247.7 Adult Eye    185.775 Adult Brain    154.9 Adult Thoracic-Abdominal Ganglion    164.7 Adult Crop    281.1 Adult Midgut    488.5 Adult Hindgut    239.8 Adult Malpighian Tubules    1000.5 Adult Fat Body    496.6 Adult Salivary Gland    226.8 Adult Heart    974.575 Adult VirginFemale Spermatheca    445 Adult InseminatedFemale Spermatheca    403 Adult Ovary    758.8 Adult Testis    1273.2 Adult Male Accessory Gland    366.2 Adult Carcass    389.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    446.625 Larval Midgut  789.7 Larval Hindgut  681.2 Larval Malpighian Tubules  (3020.1) Larval Fat Body  (1540.8) Larval Salivary Gland  (1107.8) Larval Trachea  (822.325) Larval Carcass  (1706.1) Adult Head    247.7 Adult Eye    185.775 Adult Brain    154.9 Adult Thoracic-Abdominal Ganglion    164.7 Adult Crop    281.1 Adult Midgut    488.5 Adult Hindgut    239.8 Adult Malpighian Tubules  (1000.5) Adult Fat Body    496.6 Adult Salivary Gland    226.8 Adult Heart  (974.575) Adult VirginFemale Spermatheca    445 Adult InseminatedFemale Spermatheca    403 Adult Ovary  758.8 Adult Testis  (1273.2) Adult Male Accessory Gland    366.2 Adult Carcass    389.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    446.625 Larval Midgut    789.7 Larval Hindgut    681.2 Larval Malpighian Tubules  (3020.1) Larval Fat Body  1540.8 Larval Salivary Gland  1107.8 Larval Trachea    822.325 Larval Carcass  1706.1 Adult Head    247.7 Adult Eye    185.775 Adult Brain    154.9 Adult Thoracic-Abdominal Ganglion    164.7 Adult Crop    281.1 Adult Midgut    488.5 Adult Hindgut    239.8 Adult Malpighian Tubules  1000.5 Adult Fat Body    496.6 Adult Salivary Gland    226.8 Adult Heart    974.575 Adult VirginFemale Spermatheca    445 Adult InseminatedFemale Spermatheca    403 Adult Ovary    758.8 Adult Testis  1273.2 Adult Male Accessory Gland    366.2 Adult Carcass    389.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    446.625 Larval Midgut    789.7 Larval Hindgut    681.2 Larval Malpighian Tubules    3020.1 Larval Fat Body    1540.8 Larval Salivary Gland    1107.8 Larval Trachea    822.325 Larval Carcass    1706.1 Adult Head    247.7 Adult Eye    185.775 Adult Brain    154.9 Adult Thoracic-Abdominal Ganglion    164.7 Adult Crop    281.1 Adult Midgut    488.5 Adult Hindgut    239.8 Adult Malpighian Tubules    1000.5 Adult Fat Body    496.6 Adult Salivary Gland    226.8 Adult Heart    974.575 Adult VirginFemale Spermatheca    445 Adult InseminatedFemale Spermatheca    403 Adult Ovary    758.8 Adult Testis    1273.2 Adult Male Accessory Gland    366.2 Adult Carcass    389.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    247.7   NA  Eye    185.775   NA  Brain    154.9   446.625  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    164.7   NA  Crop    281.1   789.7  Midgut    488.5   681.2  Hindgut    239.8   3020.1  Malpighian Tubules    1000.5   1540.8  Fat Body    496.6   1107.8  Salivary Gland    226.8   NA  Heart    974.575   822.325  Trachea    NA   NA  VirginFemale Spermatheca    445   NA  InseminatedFemale Spermatheca    403   NA  Ovary    758.8   NA  Testis    1273.2   NA  Male Accessory Gland    366.2   1706.1  Carcass    389.5 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    33 central nervous system, pupae P8    9 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    12 head, mated 20-day male    19 salivary gland, larvae L3 wandering    14 salivary gland, white prepupae    15 digestive system, larvae L3 wandering    76 digestive system, 1-day adult    27 digestive system, 4-day adult    18 digestive system, 20-day adult    22 fat body, larvae L3 wandering    32 fat body, white prepupae    24 fat body, pupae P8    38 carcass, larvae L3 wandering    98 carcass, 1-day adult    10 carcass, 4-day adult    12 carcass, 20-day adult    12 ovary, virgin 4-day female    76 ovary, mated 4-day female    51 testis, mated 4-day male    197 accessory gland, mated 4-day male    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (82) central nervous system, larvae L3  (33) central nervous system, pupae P8    9 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    12 head, mated 20-day male    19 salivary gland, larvae L3 wandering    14 salivary gland, white prepupae    15 digestive system, larvae L3 wandering  (76) digestive system, 1-day adult  (27) digestive system, 4-day adult    18 digestive system, 20-day adult    22 fat body, larvae L3 wandering  (32) fat body, white prepupae    24 fat body, pupae P8  (38) carcass, larvae L3 wandering  (98) carcass, 1-day adult    10 carcass, 4-day adult    12 carcass, 20-day adult    12 ovary, virgin 4-day female  (76) ovary, mated 4-day female  (51) testis, mated 4-day male  (197) accessory gland, mated 4-day male  (28) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    33 central nervous system, pupae P8    9 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    12 head, mated 20-day male    19 salivary gland, larvae L3 wandering    14 salivary gland, white prepupae    15 digestive system, larvae L3 wandering    76 digestive system, 1-day adult    27 digestive system, 4-day adult    18 digestive system, 20-day adult    22 fat body, larvae L3 wandering    32 fat body, white prepupae    24 fat body, pupae P8    38 carcass, larvae L3 wandering    98 carcass, 1-day adult    10 carcass, 4-day adult    12 carcass, 20-day adult    12 ovary, virgin 4-day female    76 ovary, mated 4-day female    51 testis, mated 4-day male  (197) accessory gland, mated 4-day male    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    33 central nervous system, pupae P8    9 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    12 head, mated 20-day male    19 salivary gland, larvae L3 wandering    14 salivary gland, white prepupae    15 digestive system, larvae L3 wandering    76 digestive system, 1-day adult    27 digestive system, 4-day adult    18 digestive system, 20-day adult    22 fat body, larvae L3 wandering    32 fat body, white prepupae    24 fat body, pupae P8    38 carcass, larvae L3 wandering    98 carcass, 1-day adult    10 carcass, 4-day adult    12 carcass, 20-day adult    12 ovary, virgin 4-day female    76 ovary, mated 4-day female    51 testis, mated 4-day male    197 accessory gland, mated 4-day male    28 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    33 central nervous system, pupae P8    9 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    12 head, mated 20-day male    19 salivary gland, larvae L3 wandering    14 salivary gland, white prepupae    15 digestive system, larvae L3 wandering    76 digestive system, 1-day adult    27 digestive system, 4-day adult    18 digestive system, 20-day adult    22 fat body, larvae L3 wandering    32 fat body, white prepupae    24 fat body, pupae P8    38 carcass, larvae L3 wandering    98 carcass, 1-day adult    10 carcass, 4-day adult    12 carcass, 20-day adult    12 ovary, virgin 4-day female    76 ovary, mated 4-day female    51 testis, mated 4-day male    197 accessory gland, mated 4-day male    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (82) central nervous system, larvae L3  (33) central nervous system, pupae P8    9 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    12 head, mated 20-day male    19 salivary gland, larvae L3 wandering    14 salivary gland, white prepupae    15 digestive system, larvae L3 wandering  (76) digestive system, 1-day adult  27 digestive system, 4-day adult    18 digestive system, 20-day adult    22 fat body, larvae L3 wandering  32 fat body, white prepupae    24 fat body, pupae P8  (38) carcass, larvae L3 wandering  (98) carcass, 1-day adult    10 carcass, 4-day adult    12 carcass, 20-day adult    12 ovary, virgin 4-day female  (76) ovary, mated 4-day female  (51) testis, mated 4-day male  (197) accessory gland, mated 4-day male  28 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    33 central nervous system, pupae P8    9 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    12 head, mated 20-day male    19 salivary gland, larvae L3 wandering    14 salivary gland, white prepupae    15 digestive system, larvae L3 wandering    76 digestive system, 1-day adult    27 digestive system, 4-day adult    18 digestive system, 20-day adult    22 fat body, larvae L3 wandering    32 fat body, white prepupae    24 fat body, pupae P8    38 carcass, larvae L3 wandering    98 carcass, 1-day adult    10 carcass, 4-day adult    12 carcass, 20-day adult    12 ovary, virgin 4-day female    76 ovary, mated 4-day female    51 testis, mated 4-day male  (197) accessory gland, mated 4-day male    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    33 central nervous system, pupae P8    9 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    12 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    12 head, mated 20-day male    19 salivary gland, larvae L3 wandering    14 salivary gland, white prepupae    15 digestive system, larvae L3 wandering    76 digestive system, 1-day adult    27 digestive system, 4-day adult    18 digestive system, 20-day adult    22 fat body, larvae L3 wandering    32 fat body, white prepupae    24 fat body, pupae P8    38 carcass, larvae L3 wandering    98 carcass, 1-day adult    10 carcass, 4-day adult    12 carcass, 20-day adult    12 ovary, virgin 4-day female    76 ovary, mated 4-day female    51 testis, mated 4-day male    197 accessory gland, mated 4-day male    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed during late larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    160 embryo 02-04hr    21 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    8 embryo 10-12hr    19 embryo 12-14hr    18 embryo 14-16hr    31 embryo 16-18hr    18 embryo 18-20hr    6 embryo 20-22hr    3 embryo 22-24hr    3 larva L1    23 larva L2    58 larva L3 12hr old    46 larva L3 puffstage 1-2    115 larva L3 puffstage 3-6    183 larva L3 puffstage 7-9    199 white prepupae new    156 white prepupae 12hr    96 white prepupae 24hr    111 pupae 2d postWPP    89 pupae 3d postWPP    81 pupae 4d postWPP    75 adult male 01day    99 adult male 05day    122 adult male 30day    125 adult female 01day    69 adult female 05day    108 adult female 30day    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (160) embryo 02-04hr    21 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    8 embryo 10-12hr    19 embryo 12-14hr    18 embryo 14-16hr  (31) embryo 16-18hr    18 embryo 18-20hr    6 embryo 20-22hr    3 embryo 22-24hr    3 larva L1    23 larva L2  (58) larva L3 12hr old  (46) larva L3 puffstage 1-2  (115) larva L3 puffstage 3-6  (183) larva L3 puffstage 7-9  (199) white prepupae new  (156) white prepupae 12hr  (96) white prepupae 24hr  (111) pupae 2d postWPP  (89) pupae 3d postWPP  (81) pupae 4d postWPP  (75) adult male 01day  (99) adult male 05day  (122) adult male 30day  (125) adult female 01day  (69) adult female 05day  (108) adult female 30day  (105) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (160) embryo 02-04hr    21 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    8 embryo 10-12hr    19 embryo 12-14hr    18 embryo 14-16hr    31 embryo 16-18hr    18 embryo 18-20hr    6 embryo 20-22hr    3 embryo 22-24hr    3 larva L1    23 larva L2    58 larva L3 12hr old    46 larva L3 puffstage 1-2  (115) larva L3 puffstage 3-6  (183) larva L3 puffstage 7-9  (199) white prepupae new  (156) white prepupae 12hr    96 white prepupae 24hr  (111) pupae 2d postWPP    89 pupae 3d postWPP    81 pupae 4d postWPP    75 adult male 01day    99 adult male 05day  (122) adult male 30day  (125) adult female 01day    69 adult female 05day  (108) adult female 30day  105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    160 embryo 02-04hr    21 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    8 embryo 10-12hr    19 embryo 12-14hr    18 embryo 14-16hr    31 embryo 16-18hr    18 embryo 18-20hr    6 embryo 20-22hr    3 embryo 22-24hr    3 larva L1    23 larva L2    58 larva L3 12hr old    46 larva L3 puffstage 1-2    115 larva L3 puffstage 3-6    183 larva L3 puffstage 7-9    199 white prepupae new    156 white prepupae 12hr    96 white prepupae 24hr    111 pupae 2d postWPP    89 pupae 3d postWPP    81 pupae 4d postWPP    75 adult male 01day    99 adult male 05day    122 adult male 30day    125 adult female 01day    69 adult female 05day    108 adult female 30day    105 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    160 embryo 02-04hr    21 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    8 embryo 10-12hr    19 embryo 12-14hr    18 embryo 14-16hr    31 embryo 16-18hr    18 embryo 18-20hr    6 embryo 20-22hr    3 embryo 22-24hr    3 larva L1    23 larva L2    58 larva L3 12hr old    46 larva L3 puffstage 1-2    115 larva L3 puffstage 3-6    183 larva L3 puffstage 7-9    199 white prepupae new    156 white prepupae 12hr    96 white prepupae 24hr    111 pupae 2d postWPP    89 pupae 3d postWPP    81 pupae 4d postWPP    75 adult male 01day    99 adult male 05day    122 adult male 30day    125 adult female 01day    69 adult female 05day    108 adult female 30day    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (160) embryo 02-04hr    21 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    8 embryo 10-12hr    19 embryo 12-14hr    18 embryo 14-16hr  31 embryo 16-18hr    18 embryo 18-20hr    6 embryo 20-22hr    3 embryo 22-24hr    3 larva L1    23 larva L2  (58) larva L3 12hr old  (46) larva L3 puffstage 1-2  (115) larva L3 puffstage 3-6  (183) larva L3 puffstage 7-9  (199) white prepupae new  (156) white prepupae 12hr  (96) white prepupae 24hr  (111) pupae 2d postWPP  (89) pupae 3d postWPP  (81) pupae 4d postWPP  (75) adult male 01day  (99) adult male 05day  (122) adult male 30day  (125) adult female 01day  (69) adult female 05day  (108) adult female 30day  (105) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (160) embryo 02-04hr    21 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    8 embryo 10-12hr    19 embryo 12-14hr    18 embryo 14-16hr    31 embryo 16-18hr    18 embryo 18-20hr    6 embryo 20-22hr    3 embryo 22-24hr    3 larva L1    23 larva L2    58 larva L3 12hr old    46 larva L3 puffstage 1-2  115 larva L3 puffstage 3-6  (183) larva L3 puffstage 7-9  (199) white prepupae new  (156) white prepupae 12hr    96 white prepupae 24hr  111 pupae 2d postWPP    89 pupae 3d postWPP    81 pupae 4d postWPP    75 adult male 01day    99 adult male 05day  122 adult male 30day  125 adult female 01day    69 adult female 05day  108 adult female 30day  105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    160 embryo 02-04hr    21 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    8 embryo 10-12hr    19 embryo 12-14hr    18 embryo 14-16hr    31 embryo 16-18hr    18 embryo 18-20hr    6 embryo 20-22hr    3 embryo 22-24hr    3 larva L1    23 larva L2    58 larva L3 12hr old    46 larva L3 puffstage 1-2    115 larva L3 puffstage 3-6    183 larva L3 puffstage 7-9    199 white prepupae new    156 white prepupae 12hr    96 white prepupae 24hr    111 pupae 2d postWPP    89 pupae 3d postWPP    81 pupae 4d postWPP    75 adult male 01day    99 adult male 05day    122 adult male 30day    125 adult female 01day    69 adult female 05day    108 adult female 30day    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    119 Schneider line 2 Sg4    327 embryonic 1182-4H    35 embryonic GM2    99 embryonic Kc167    99 embryonic S1    98 embryonic S3    318 leg disc CME L1    206 wing disc CME-W2    169 wing disc ML-DmD8    57 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    69 wing disc ML-DmD21    275 wing disc ML-DmD32    36 haltere disc ML-DmD17-c3    129 eye-antennal disc ML-DmD11    52 antennal disc ML-DmD20-c5    62 mixed discs ML-DmD4-c1    73 CNS ML-DmBG1-c1    32 CNS ML-DmBG2-c2    96 tumorous blood cells mbn2    52 ovary fGS/OSS    14 ovary OSC    10 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (119) Schneider line 2 Sg4  (327) embryonic 1182-4H  (35) embryonic GM2  (99) embryonic Kc167  (99) embryonic S1  (98) embryonic S3  (318) leg disc CME L1  (206) wing disc CME-W2  (169) wing disc ML-DmD8  (57) wing disc ML-DmD9  (59) wing disc ML-DmD16-c3  (69) wing disc ML-DmD21  (275) wing disc ML-DmD32  (36) haltere disc ML-DmD17-c3  (129) eye-antennal disc ML-DmD11  (52) antennal disc ML-DmD20-c5  (62) mixed discs ML-DmD4-c1  (73) CNS ML-DmBG1-c1  (32) CNS ML-DmBG2-c2  (96) tumorous blood cells mbn2  (52) ovary fGS/OSS    14 ovary OSC    10 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (119) Schneider line 2 Sg4  (327) embryonic 1182-4H    35 embryonic GM2    99 embryonic Kc167    99 embryonic S1    98 embryonic S3  (318) leg disc CME L1  (206) wing disc CME-W2  (169) wing disc ML-DmD8    57 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    69 wing disc ML-DmD21  (275) wing disc ML-DmD32    36 haltere disc ML-DmD17-c3  (129) eye-antennal disc ML-DmD11    52 antennal disc ML-DmD20-c5    62 mixed discs ML-DmD4-c1    73 CNS ML-DmBG1-c1    32 CNS ML-DmBG2-c2    96 tumorous blood cells mbn2    52 ovary fGS/OSS    14 ovary OSC    10 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    119 Schneider line 2 Sg4    327 embryonic 1182-4H    35 embryonic GM2    99 embryonic Kc167    99 embryonic S1    98 embryonic S3    318 leg disc CME L1    206 wing disc CME-W2    169 wing disc ML-DmD8    57 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    69 wing disc ML-DmD21    275 wing disc ML-DmD32    36 haltere disc ML-DmD17-c3    129 eye-antennal disc ML-DmD11    52 antennal disc ML-DmD20-c5    62 mixed discs ML-DmD4-c1    73 CNS ML-DmBG1-c1    32 CNS ML-DmBG2-c2    96 tumorous blood cells mbn2    52 ovary fGS/OSS    14 ovary OSC    10 ovary OSS    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    119 Schneider line 2 Sg4    327 embryonic 1182-4H    35 embryonic GM2    99 embryonic Kc167    99 embryonic S1    98 embryonic S3    318 leg disc CME L1    206 wing disc CME-W2    169 wing disc ML-DmD8    57 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    69 wing disc ML-DmD21    275 wing disc ML-DmD32    36 haltere disc ML-DmD17-c3    129 eye-antennal disc ML-DmD11    52 antennal disc ML-DmD20-c5    62 mixed discs ML-DmD4-c1    73 CNS ML-DmBG1-c1    32 CNS ML-DmBG2-c2    96 tumorous blood cells mbn2    52 ovary fGS/OSS    14 ovary OSC    10 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (119) Schneider line 2 Sg4  (327) embryonic 1182-4H  (35) embryonic GM2  (99) embryonic Kc167  (99) embryonic S1  (98) embryonic S3  (318) leg disc CME L1  (206) wing disc CME-W2  (169) wing disc ML-DmD8  (57) wing disc ML-DmD9  (59) wing disc ML-DmD16-c3  (69) wing disc ML-DmD21  (275) wing disc ML-DmD32  (36) haltere disc ML-DmD17-c3  (129) eye-antennal disc ML-DmD11  (52) antennal disc ML-DmD20-c5  (62) mixed discs ML-DmD4-c1  (73) CNS ML-DmBG1-c1  32 CNS ML-DmBG2-c2  (96) tumorous blood cells mbn2  (52) ovary fGS/OSS    14 ovary OSC    10 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  119 Schneider line 2 Sg4  (327) embryonic 1182-4H    35 embryonic GM2    99 embryonic Kc167    99 embryonic S1    98 embryonic S3  (318) leg disc CME L1  (206) wing disc CME-W2  (169) wing disc ML-DmD8    57 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    69 wing disc ML-DmD21  (275) wing disc ML-DmD32    36 haltere disc ML-DmD17-c3  129 eye-antennal disc ML-DmD11    52 antennal disc ML-DmD20-c5    62 mixed discs ML-DmD4-c1    73 CNS ML-DmBG1-c1    32 CNS ML-DmBG2-c2    96 tumorous blood cells mbn2    52 ovary fGS/OSS    14 ovary OSC    10 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    119 Schneider line 2 Sg4    327 embryonic 1182-4H    35 embryonic GM2    99 embryonic Kc167    99 embryonic S1    98 embryonic S3    318 leg disc CME L1    206 wing disc CME-W2    169 wing disc ML-DmD8    57 wing disc ML-DmD9    59 wing disc ML-DmD16-c3    69 wing disc ML-DmD21    275 wing disc ML-DmD32    36 haltere disc ML-DmD17-c3    129 eye-antennal disc ML-DmD11    52 antennal disc ML-DmD20-c5    62 mixed discs ML-DmD4-c1    73 CNS ML-DmBG1-c1    32 CNS ML-DmBG2-c2    96 tumorous blood cells mbn2    52 ovary fGS/OSS    14 ovary OSC    10 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    23 cold shock, 4-day adult    20 heat shock, 4-day adult    48 Cadmium 50 mM 6 hrs, larvae L3    54 Cadmium 50 mM 12 hrs, larvae L3    85 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    46 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    67 Ethanol 5% 3 hrs, larvae L3    33 Ethanol 10% 3 hrs, larvae L3    40 Caffeine 1.5 mg/ml 4 hrs, larvae L3    51 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    45 Paraquat 10 mM 48 hrs, 4-day adult    68 Rotenone 2 μg 12 hrs, larvae L3    55 Rotenone 8 μg 12 hrs, larvae L3    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    23 cold shock, 4-day adult    20 heat shock, 4-day adult  (48) Cadmium 50 mM 6 hrs, larvae L3  (54) Cadmium 50 mM 12 hrs, larvae L3  (85) Cadmium 50 mM 48 hrs, 4-day adult  (45) Cadmium 100 mM 48 hrs, 4-day adult  (46) Copper 0.5 mM 12 hrs, larvae L3  (30) Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3  (67) Ethanol 5% 3 hrs, larvae L3  (33) Ethanol 10% 3 hrs, larvae L3  (40) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (51) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (34) Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult  (45) Paraquat 10 mM 48 hrs, 4-day adult  (68) Rotenone 2 μg 12 hrs, larvae L3  (55) Rotenone 8 μg 12 hrs, larvae L3  (40) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    23 cold shock, 4-day adult    20 heat shock, 4-day adult    48 Cadmium 50 mM 6 hrs, larvae L3    54 Cadmium 50 mM 12 hrs, larvae L3    85 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    46 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    67 Ethanol 5% 3 hrs, larvae L3    33 Ethanol 10% 3 hrs, larvae L3    40 Caffeine 1.5 mg/ml 4 hrs, larvae L3    51 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    45 Paraquat 10 mM 48 hrs, 4-day adult    68 Rotenone 2 μg 12 hrs, larvae L3    55 Rotenone 8 μg 12 hrs, larvae L3    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    23 cold shock, 4-day adult    20 heat shock, 4-day adult    48 Cadmium 50 mM 6 hrs, larvae L3    54 Cadmium 50 mM 12 hrs, larvae L3    85 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    46 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    67 Ethanol 5% 3 hrs, larvae L3    33 Ethanol 10% 3 hrs, larvae L3    40 Caffeine 1.5 mg/ml 4 hrs, larvae L3    51 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    45 Paraquat 10 mM 48 hrs, 4-day adult    68 Rotenone 2 μg 12 hrs, larvae L3    55 Rotenone 8 μg 12 hrs, larvae L3    40 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    23 cold shock, 4-day adult    20 heat shock, 4-day adult    48 Cadmium 50 mM 6 hrs, larvae L3    54 Cadmium 50 mM 12 hrs, larvae L3    85 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    46 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    67 Ethanol 5% 3 hrs, larvae L3    33 Ethanol 10% 3 hrs, larvae L3    40 Caffeine 1.5 mg/ml 4 hrs, larvae L3    51 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    45 Paraquat 10 mM 48 hrs, 4-day adult    68 Rotenone 2 μg 12 hrs, larvae L3    55 Rotenone 8 μg 12 hrs, larvae L3    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    23 cold shock, 4-day adult    20 heat shock, 4-day adult  (48) Cadmium 50 mM 6 hrs, larvae L3  (54) Cadmium 50 mM 12 hrs, larvae L3  (85) Cadmium 50 mM 48 hrs, 4-day adult  (45) Cadmium 100 mM 48 hrs, 4-day adult  (46) Copper 0.5 mM 12 hrs, larvae L3  30 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3  (67) Ethanol 5% 3 hrs, larvae L3  (33) Ethanol 10% 3 hrs, larvae L3  (40) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (51) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (34) Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult  (45) Paraquat 10 mM 48 hrs, 4-day adult  (68) Rotenone 2 μg 12 hrs, larvae L3  (55) Rotenone 8 μg 12 hrs, larvae L3  (40) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    23 cold shock, 4-day adult    20 heat shock, 4-day adult    48 Cadmium 50 mM 6 hrs, larvae L3    54 Cadmium 50 mM 12 hrs, larvae L3    85 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    46 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    67 Ethanol 5% 3 hrs, larvae L3    33 Ethanol 10% 3 hrs, larvae L3    40 Caffeine 1.5 mg/ml 4 hrs, larvae L3    51 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    45 Paraquat 10 mM 48 hrs, 4-day adult    68 Rotenone 2 μg 12 hrs, larvae L3    55 Rotenone 8 μg 12 hrs, larvae L3    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    23 cold shock, 4-day adult    20 heat shock, 4-day adult    48 Cadmium 50 mM 6 hrs, larvae L3    54 Cadmium 50 mM 12 hrs, larvae L3    85 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    46 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    67 Ethanol 5% 3 hrs, larvae L3    33 Ethanol 10% 3 hrs, larvae L3    40 Caffeine 1.5 mg/ml 4 hrs, larvae L3    51 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    45 Paraquat 10 mM 48 hrs, 4-day adult    68 Rotenone 2 μg 12 hrs, larvae L3    55 Rotenone 8 μg 12 hrs, larvae L3    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_02
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040493 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7340-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | recessive grsmc00064 viable grsmEY07602 viable, with Scer\GAL4pnr-MD237 grsmGD1602 Sterility Allele fertile grsmEY07602 Phenotype manifest in Allele
Classical Alleles ( 10 )
For All Classical Alleles Show
Allele of grsm Class Mutagen Stocks Known lesion grsmc00064 piggyBac transposase 1 -- grsmc02455 piggyBac transposase 1 -- grsme03202 1 -- grsme04434 piggyBac transposase 1 -- grsmEY07602 P-element activity 1 -- grsmf01037 piggyBac transposase 1 -- grsmMB03043 1 -- grsmMI03766 1 -- grsmPL00025 1 Yes grsmc02719 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of grsm Class Mutagen Stocks Known lesion grsmGD1602 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes grsmNIG.7340-1R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes grsmNIG.7340R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel7318 (Ryder, 2004.4.26) Df(3R)ry615 (Thibault et al., 2004)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{NIG.7340-1R} NA P{NIG.7340R} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}grsmEY07602 NA miscellaneous insertions Mi{MIC}grsmMI03766 NA PBac{PB}grsmc00064 NA PBac{PB}grsmc02455 NA PBac{PB}grsmc02719 NA PBac{RB}grsme03202 NA PBac{RB}grsme04434 NA PBac{WH}grsmf01037 NA insertion of enhancer trap binary system Mi{ET1}grsmMB03043 No PBac{GAL4D,EYFP}Cyp304a1PL00025 No insertion of enhancer trap P{lacW}CK4A No
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
aminopeptidase activity inferred from sequence or structural similarity (Kirkpatrick, 1999.12.23, Kirkpatrick, 1999.12.23) inferred from sequence or structural similarity with EMBL:AF061738 (FlyBase, 1992-) manganese ion binding inferred from electronic annotation with InterPro:IPR011356 (FlyBase Curators et al., 2004-) metalloexopeptidase activity inferred from electronic annotation with InterPro:IPR011356 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
proteolysis inferred from electronic annotation with InterPro:IPR000819 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
cytoplasm inferred from electronic annotation with InterPro:IPR011356 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Kirkpatrick, 1999.12.23, Kirkpatrick, 1999.12.23)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
grsm - Bacc experimental knowledge based (Guruharsha et al., 2011) grsm - CG1105 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - CG13321 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - CG31917 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - CG3907 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - CG5577 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - CG6674 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - CG8036 experimental knowledge based (Guruharsha et al., 2011) grsm - CG9773 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - CG9977 experimental knowledge based (Guruharsha et al., 2011) grsm - Eig71Ed anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - Mcm3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - Nf-YA anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - RpS21 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - Tpi experimental knowledge based (Guruharsha et al., 2011) grsm - Treh experimental knowledge based (Guruharsha et al., 2011) grsm - aur anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - mib2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - papi anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) grsm - pr experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions grsm allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66676 DroID - A comprehensive database of gene and protein interactions. • FBgn0040493 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41587
Orthologs
OrthoDB Orthologs (29) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG622B4D Dipteran inclusive ortholog search EOG6M920R Insect inclusive ortholog search EOG6HDRPP Arthropod inclusive ortholog search EOG6KPRS2 Metazoa inclusive ortholog search EOG69SK0Q
Orthologs in Drosophila Species (EOG622B4D)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\grsm     Drosophila simulans   Dsim\GD20533 Y   Drosophila sechellia   Dsec\GM25972 Y   Drosophila erecta   Dere\GG17089 Y   Drosophila yakuba   Dyak\GE24479 Y   Drosophila ananassae   Dana\GF18094 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA20276     Drosophila persimilis   Dper\GL23157 Y   Drosophila willistoni   Dwil\GK10859 Y   Drosophila virilis   Dvir\GJ10808 Y   Drosophila mojavensis   Dmoj\GI24235 Y   Drosophila grimshawi   Dgri\GH19202 Y
Orthologs in non-Drosophila Dipterans (EOG6M920R)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001649   Anopheles gambiae Malaria mosquito  Agam\AGAP007809   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ802305
Orthologs in non-Dipteran Insects (EOG6HDRPP)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Acyrthosiphon pisum Pea aphid  Apim\ACYPI002904   Bombyx mori Silkmoth  Bmor\BGIBMGA009138   Tribolium castaneum Red flour beetle  Tcas\TC015913
Orthologs in non-Insect Arthropods (EOG6KPRS2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Tubb6   Ixodes scapularis Deer tick  Isca\ISCW023735
Orthologs in non-Arthropod Metazoa (EOG69SK0Q)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\lap-1   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025520gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025459gn   Danio rerio Zebrafish  Drer\npepl1   Xenopus tropicalis Western clawed frog  Xtro\npepl1   Gallus gallus Domestic chicken  Ggal\NPEPL1   Mus musculus House mouse  Mmus\Npepl1   Rattus norvegicus Norway rat  Rnor\Npepl1   Homo sapiens Human  Hsap\NPEPL1
Human Orthologs (1)
Gene OMIM HGNC Hsap\NPEPL1
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD20533 Drosophila sechellia Dsec\GM25972 Drosophila erecta Dere\GG17089 Drosophila yakuba Dyak\GE24479 Drosophila ananassae Dana\GF18094 Drosophila persimilis Dper\GL23157 Drosophila willistoni Dwil\GK10859 Drosophila virilis Dvir\GJ10808 Drosophila mojavensis Dmoj\GI24235 Drosophila grimshawi Dgri\GH19202
Stocks & Reagents
Stocks Listed in FlyBase ( 11 )
Bloomington	24045 w1118; Mi{ET1}grsmMB03043 37223 y1 w*; Mi{MIC}grsmMI03766 16850 y1 w67c23; P{EPgy2}grsmEY07602 19618 w*; P{FRT(whs)}2A P{neoFRT}82B PBac{GAL4D,EYFP}Cyp304a1PL00025 grsmPL00025
Harvard	- PBac{PB}grsmc00064 - PBac{PB}grsmc02455 - PBac{RB}grsme03202 - PBac{RB}grsme04434 - PBac{WH}grsmf01037
VDRC	v3175 w1118; P{GD1602}v3175 v3174 w1118; P{GD1602}v3174/TM3
Genomic Clones ( 1 )
	BACR17F05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 109 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT31511 GH27579
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT04636 AT05303 AT08080 AT11626 AT11663 AT12593 AT14170 AT16519 AT17327 AT17803 AT18006 AT20074 AT20089 AT22388 AT22752 AT23454 AT23992 AT25537 AT26095 AT28463 AT29419 AT29746 AT29749 AT30162 AT30344 AT31383 AT31615 GH28310 GM04146 GM10727 GM12805 LD26518 LD34492 LD41548 LP15373 LP19767 LP19806 LP22403 RE39075 RE41181 RE53016 SD04712 SD10759 SD12068 SD16331
Other clones	19026 59773 70105 154338 214543.59 AT01020 bs30d10 bs70g02 bs72b07 CK01.55B.D5 EC051626 EC054615 EC056410 EK038538 EK044915 EK133621 EK160408 EK186320 EK197528 EK255005 EK258020 EK290534 EP08654 IP05331 LD13869 LD23867 RP003024254 RP003053842 RP003053991 RP003119851 RP003162485 RP003166241 RP003181600 RP003208443 RP003220110 RP003251768 RP003253860 RP003255563 RP003261251 RP003269232 RP003271553 RP003272938 RP003277643 RP003282116 RP003282526 RP003286095 RP003288963 RP003329217 RP003403682 RP003437098 RP003437379 RP003440016 RP003471748 RP003484885 RP003500828 RP003504888 RP003543053 RP003584156 RP003630864 RP003639196 RP003645376 RP003662082
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0040493 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41587
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: granny-smith BcDNA:LD41548 (Kirkpatrick et al., 2003)
Source for database merge of	Source for merge of: BcDNA:LD41548 CG7340 (Peifer, 2000.4.6)
Additional comments
Other Comments
	RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141983 NM_169482 RefSeq (Proteins) • NP_650240 NP_731749 DDBJ / EMBL / GenBank • AA439330 AA802289 AAF32328 AAF32329 AAF54873 AAF54874 AAF54877 AAN71126 AF218811 AF218812 AI515859 AI533034 AI946765 AW942289 BG635052 BT001371 CL528046 CZ466173 CZ467957 CZ482194 CZ483524 Entrez Gene - A searchable database of RefSeq genes. • 41587 UniProtKB/TrEMBL • Q8IH82 Q9NHV8 Q9V3D8 Q9VG16
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Peptidase M17, leucyl aminopeptidase, C-terminal (IPR000819) Leucine aminopeptidase/peptidase B (IPR011356)
Linkouts
	BioGRID - A database of protein and genetic interactions • 66676 DroID - A comprehensive database of gene and protein interactions. • FBgn0040493 DRSC - Results from RNAi screens. • FBgn0040493 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040493 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7340-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0040493 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41587 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41587 modMine - Data generated by the modENCODE project. • FBgn0040493
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	BcDNA:LD41548 (Boutros et al., 2004, Giot et al., 2003, ) CG7340 (Kirkpatrick et al., 2003, Peifer, 2000.4.6, Williams et al., 2007, Cammarato et al., 2011, Lundgren et al., 2005) granny-smith (Dorus et al., 2011, Japanese National Institute of Genetics, 2012.5.21) granny smith (Gonsalves et al., 2011) grsm (Williams et al., 2007) l(3)c00064   unnamed (Thibault et al., 2004)
Name Synonym	aminopeptidase (Kirkpatrick et al., 2002) granny-smith (Gan et al., 2010) granny smith (Cammarato et al., 2011, Kirkpatrick et al., 2003, Williams et al., 2007, ) lethal (3) c00064   Leucyl-aminopeptidase (Lundgren et al., 2005)
Secondary FlyBase IDs
	FBgn0038096 FBgn0069190
References ( 34 )
Generate a list of	All references relating to this gene ( 34 )
List References by type	Research paper  ( 7 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 12 ) Abstract  ( 2 ) FlyBase analysis  ( 3 ) Stock list  ( 1 ) DNA/RNA sequence record  ( 2 ) Curated genome annotation  ( 1 )
Recent research papers ( 2 )
	Dorus et al., 2011, BMC Genomics 12: 177 Expansion and functional diversification of a leucyl aminopeptidase family that encodes the major protein constituents of Drosophila sperm. [FBrf0213467] Gonsalves et al., 2011, BMC Genomics 12: 475 Genome-wide examination of the transcriptional response to ecdysteroids 20-hydroxyecdysone and ponasterone A in Drosophila melanogaster. [FBrf0216487] Show all research papers ...