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Gene Dmel\CG13631

General Information
Symbol	Dmel\CG13631	Species	D. melanogaster
Name		Annotation symbol	CG13631
Feature type	protein_coding_gene	FlyBase ID	FBgn0040600
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	96A20-96A20	Sequence location	3R:20,595,073..20,596,655 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG13631 (FBgn0040600). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult hindgut, adult Malpighian tubules, adult heart, adult salivary gland, larval trachea, adult spermathecae. Expression at moderate levels in the following post-embryonic organs or tissues: larval hindgut, larval Malpighian tubules, adult fat body, larval salivary gland, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1639443_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG13631. Gene sequence location is 3R:20595073..20596655.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 96A20-96A20   Limits computationally determined from genome sequence between P{PZ}crb07207&P{PZ}BRWD305842 and P{EP}CycB3EP3127
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG13631 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG13631-RA FBtr0084693  NM_143995   761   83 CG13631-RB FBtr0339253     1583   83
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG13631-PA   FBpp0084072   9.1   83   10.06     NP_652252   AAF56332 CG13631-PB   FBpp0308360   9.1   83   10.06
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF56332   AI388438   AW940737   AY060742 AAL28290   BI232279   BI238756   BI565678   BI567188   BI567191   BI567257   BI585013   BI588345   BI613445   BI616297   BI623049   BI624524   BI630212   BT125115   BT125116   CK660499   CO267382   CO276340   CO277155   CO300342   CO304012   CO304519   CO311301   CO312207   CO321083   CO328753   EC082619   EC082939   EC087674   EC090168   EC225074   EC233154   EC240675   EC248732   GH740174   GH740389   GH745643   GH765624   GH766467   GH767909
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VC43
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 13 -- 16   atrium   (Fisher et al., 2012) embryonic dorsal epidermis   (Fisher et al., 2012) embryonic epipharynx   (Fisher et al., 2012) embryonic esophagus   (Fisher et al., 2012) embryonic foregut   (Fisher et al., 2012) embryonic head epidermis   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic hypopharynx   (Fisher et al., 2012) embryonic proventriculus   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012) embryonic/larval posterior spiracle   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult hindgut, adult Malpighian tubules, adult heart, adult salivary gland, larval trachea, adult spermathecae. Expression at moderate levels in the following post-embryonic organs or tissues: larval hindgut, larval Malpighian tubules, adult fat body, larval salivary gland, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    64.425 Larval Midgut    76.2 Larval Hindgut    226.7 Larval Malpighian Tubules    118.2 Larval Fat Body    40.1 Larval Salivary Gland    426.1 Larval Trachea    571.7 Larval Carcass    203.775 Adult Head    828.8 Adult Eye    1920.35 Adult Brain    870.8 Adult Thoracic-Abdominal Ganglion    1207.6 Adult Crop    653.3 Adult Midgut    94 Adult Hindgut    590.4 Adult Malpighian Tubules    594.3 Adult Fat Body    485.7 Adult Salivary Gland    928 Adult Heart    1522.55 Adult VirginFemale Spermatheca    511.2 Adult InseminatedFemale Spermatheca    842.2 Adult Ovary    27.5 Adult Testis    62.5 Adult Male Accessory Gland    227.2 Adult Carcass    478.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    64.425 Larval Midgut    76.2 Larval Hindgut    226.7 Larval Malpighian Tubules    118.2 Larval Fat Body    40.1 Larval Salivary Gland    426.1 Larval Trachea  (571.7) Larval Carcass    203.775 Adult Head  (828.8) Adult Eye  (1920.35) Adult Brain  (870.8) Adult Thoracic-Abdominal Ganglion  (1207.6) Adult Crop  (653.3) Adult Midgut    94 Adult Hindgut  (590.4) Adult Malpighian Tubules  (594.3) Adult Fat Body    485.7 Adult Salivary Gland  (928) Adult Heart  (1522.55) Adult VirginFemale Spermatheca  511.2 Adult InseminatedFemale Spermatheca  (842.2) Adult Ovary    27.5 Adult Testis    62.5 Adult Male Accessory Gland    227.2 Adult Carcass    478.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    64.425 Larval Midgut    76.2 Larval Hindgut    226.7 Larval Malpighian Tubules    118.2 Larval Fat Body    40.1 Larval Salivary Gland    426.1 Larval Trachea    571.7 Larval Carcass    203.775 Adult Head    828.8 Adult Eye  (1920.35) Adult Brain    870.8 Adult Thoracic-Abdominal Ganglion  (1207.6) Adult Crop    653.3 Adult Midgut    94 Adult Hindgut    590.4 Adult Malpighian Tubules    594.3 Adult Fat Body    485.7 Adult Salivary Gland    928 Adult Heart  (1522.55) Adult VirginFemale Spermatheca    511.2 Adult InseminatedFemale Spermatheca    842.2 Adult Ovary    27.5 Adult Testis    62.5 Adult Male Accessory Gland    227.2 Adult Carcass    478.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    64.425 Larval Midgut    76.2 Larval Hindgut    226.7 Larval Malpighian Tubules    118.2 Larval Fat Body    40.1 Larval Salivary Gland    426.1 Larval Trachea    571.7 Larval Carcass    203.775 Adult Head    828.8 Adult Eye    1920.35 Adult Brain    870.8 Adult Thoracic-Abdominal Ganglion    1207.6 Adult Crop    653.3 Adult Midgut    94 Adult Hindgut    590.4 Adult Malpighian Tubules    594.3 Adult Fat Body    485.7 Adult Salivary Gland    928 Adult Heart    1522.55 Adult VirginFemale Spermatheca    511.2 Adult InseminatedFemale Spermatheca    842.2 Adult Ovary    27.5 Adult Testis    62.5 Adult Male Accessory Gland    227.2 Adult Carcass    478.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    64.425 Larval Midgut    76.2 Larval Hindgut    226.7 Larval Malpighian Tubules    118.2 Larval Fat Body    40.1 Larval Salivary Gland    426.1 Larval Trachea    571.7 Larval Carcass    203.775 Adult Head    828.8 Adult Eye    1920.35 Adult Brain    870.8 Adult Thoracic-Abdominal Ganglion    1207.6 Adult Crop    653.3 Adult Midgut    94 Adult Hindgut    590.4 Adult Malpighian Tubules    594.3 Adult Fat Body    485.7 Adult Salivary Gland    928 Adult Heart    1522.55 Adult VirginFemale Spermatheca    511.2 Adult InseminatedFemale Spermatheca    842.2 Adult Ovary    27.5 Adult Testis    62.5 Adult Male Accessory Gland    227.2 Adult Carcass    478.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    64.425 Larval Midgut    76.2 Larval Hindgut    226.7 Larval Malpighian Tubules    118.2 Larval Fat Body    40.1 Larval Salivary Gland    426.1 Larval Trachea  571.7 Larval Carcass    203.775 Adult Head  (828.8) Adult Eye  (1920.35) Adult Brain  (870.8) Adult Thoracic-Abdominal Ganglion  (1207.6) Adult Crop  653.3 Adult Midgut    94 Adult Hindgut  590.4 Adult Malpighian Tubules  594.3 Adult Fat Body    485.7 Adult Salivary Gland  (928) Adult Heart  (1522.55) Adult VirginFemale Spermatheca  511.2 Adult InseminatedFemale Spermatheca  (842.2) Adult Ovary    27.5 Adult Testis    62.5 Adult Male Accessory Gland    227.2 Adult Carcass    478.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    64.425 Larval Midgut    76.2 Larval Hindgut    226.7 Larval Malpighian Tubules    118.2 Larval Fat Body    40.1 Larval Salivary Gland    426.1 Larval Trachea    571.7 Larval Carcass    203.775 Adult Head    828.8 Adult Eye  (1920.35) Adult Brain    870.8 Adult Thoracic-Abdominal Ganglion  1207.6 Adult Crop    653.3 Adult Midgut    94 Adult Hindgut    590.4 Adult Malpighian Tubules    594.3 Adult Fat Body    485.7 Adult Salivary Gland    928 Adult Heart  1522.55 Adult VirginFemale Spermatheca    511.2 Adult InseminatedFemale Spermatheca    842.2 Adult Ovary    27.5 Adult Testis    62.5 Adult Male Accessory Gland    227.2 Adult Carcass    478.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    64.425 Larval Midgut    76.2 Larval Hindgut    226.7 Larval Malpighian Tubules    118.2 Larval Fat Body    40.1 Larval Salivary Gland    426.1 Larval Trachea    571.7 Larval Carcass    203.775 Adult Head    828.8 Adult Eye    1920.35 Adult Brain    870.8 Adult Thoracic-Abdominal Ganglion    1207.6 Adult Crop    653.3 Adult Midgut    94 Adult Hindgut    590.4 Adult Malpighian Tubules    594.3 Adult Fat Body    485.7 Adult Salivary Gland    928 Adult Heart    1522.55 Adult VirginFemale Spermatheca    511.2 Adult InseminatedFemale Spermatheca    842.2 Adult Ovary    27.5 Adult Testis    62.5 Adult Male Accessory Gland    227.2 Adult Carcass    478.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    828.8   NA  Eye    1920.35   NA  Brain    870.8   64.425  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1207.6   NA  Crop    653.3   76.2  Midgut    94   226.7  Hindgut    590.4   118.2  Malpighian Tubules    594.3   40.1  Fat Body    485.7   426.1  Salivary Gland    928   NA  Heart    1522.55   571.7  Trachea    NA   NA  VirginFemale Spermatheca    511.2   NA  InseminatedFemale Spermatheca    842.2   NA  Ovary    27.5   NA  Testis    62.5   NA  Male Accessory Gland    227.2   203.775  Carcass    478.5 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    3 central nervous system, pupae P8    26 head, virgin 1-day female    19 head, virgin 4-day female    26 head, virgin 20-day female    20 head, mated 1-day female    24 head, mated 4-day female    26 head, mated 20-day female    19 head, mated 1-day male    30 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    31 salivary gland, white prepupae    174 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    8 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    3 fat body, white prepupae    3 fat body, pupae P8    57 carcass, larvae L3 wandering    8 carcass, 1-day adult    26 carcass, 4-day adult    32 carcass, 20-day adult    34 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    3 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    3 central nervous system, pupae P8  26 head, virgin 1-day female    19 head, virgin 4-day female  26 head, virgin 20-day female    20 head, mated 1-day female    24 head, mated 4-day female  26 head, mated 20-day female    19 head, mated 1-day male  (30) head, mated 4-day male  (44) head, mated 20-day male  (45) salivary gland, larvae L3 wandering  (31) salivary gland, white prepupae  (174) digestive system, larvae L3 wandering    4 digestive system, 1-day adult    8 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    3 fat body, white prepupae    3 fat body, pupae P8  (57) carcass, larvae L3 wandering    8 carcass, 1-day adult  26 carcass, 4-day adult  (32) carcass, 20-day adult  (34) ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    3 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    3 central nervous system, pupae P8    26 head, virgin 1-day female    19 head, virgin 4-day female    26 head, virgin 20-day female    20 head, mated 1-day female    24 head, mated 4-day female    26 head, mated 20-day female    19 head, mated 1-day male    30 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    31 salivary gland, white prepupae  (174) digestive system, larvae L3 wandering    4 digestive system, 1-day adult    8 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    3 fat body, white prepupae    3 fat body, pupae P8    57 carcass, larvae L3 wandering    8 carcass, 1-day adult    26 carcass, 4-day adult    32 carcass, 20-day adult    34 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    3 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    3 central nervous system, pupae P8    26 head, virgin 1-day female    19 head, virgin 4-day female    26 head, virgin 20-day female    20 head, mated 1-day female    24 head, mated 4-day female    26 head, mated 20-day female    19 head, mated 1-day male    30 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    31 salivary gland, white prepupae    174 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    8 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    3 fat body, white prepupae    3 fat body, pupae P8    57 carcass, larvae L3 wandering    8 carcass, 1-day adult    26 carcass, 4-day adult    32 carcass, 20-day adult    34 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    3 accessory gland, mated 4-day male    15 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    3 central nervous system, pupae P8    26 head, virgin 1-day female    19 head, virgin 4-day female    26 head, virgin 20-day female    20 head, mated 1-day female    24 head, mated 4-day female    26 head, mated 20-day female    19 head, mated 1-day male    30 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    31 salivary gland, white prepupae    174 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    8 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    3 fat body, white prepupae    3 fat body, pupae P8    57 carcass, larvae L3 wandering    8 carcass, 1-day adult    26 carcass, 4-day adult    32 carcass, 20-day adult    34 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    3 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    3 central nervous system, pupae P8  26 head, virgin 1-day female    19 head, virgin 4-day female  26 head, virgin 20-day female    20 head, mated 1-day female    24 head, mated 4-day female  26 head, mated 20-day female    19 head, mated 1-day male  30 head, mated 4-day male  (44) head, mated 20-day male  (45) salivary gland, larvae L3 wandering  31 salivary gland, white prepupae  (174) digestive system, larvae L3 wandering    4 digestive system, 1-day adult    8 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    3 fat body, white prepupae    3 fat body, pupae P8  (57) carcass, larvae L3 wandering    8 carcass, 1-day adult  26 carcass, 4-day adult  32 carcass, 20-day adult  (34) ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    3 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    3 central nervous system, pupae P8    26 head, virgin 1-day female    19 head, virgin 4-day female    26 head, virgin 20-day female    20 head, mated 1-day female    24 head, mated 4-day female    26 head, mated 20-day female    19 head, mated 1-day male    30 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    31 salivary gland, white prepupae  (174) digestive system, larvae L3 wandering    4 digestive system, 1-day adult    8 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    3 fat body, white prepupae    3 fat body, pupae P8    57 carcass, larvae L3 wandering    8 carcass, 1-day adult    26 carcass, 4-day adult    32 carcass, 20-day adult    34 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    3 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    3 central nervous system, pupae P8    26 head, virgin 1-day female    19 head, virgin 4-day female    26 head, virgin 20-day female    20 head, mated 1-day female    24 head, mated 4-day female    26 head, mated 20-day female    19 head, mated 1-day male    30 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    31 salivary gland, white prepupae    174 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    8 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    3 fat body, white prepupae    3 fat body, pupae P8    57 carcass, larvae L3 wandering    8 carcass, 1-day adult    26 carcass, 4-day adult    32 carcass, 20-day adult    34 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    3 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    6 embryo 10-12hr    35 embryo 12-14hr    123 embryo 14-16hr    142 embryo 16-18hr    48 embryo 18-20hr    24 embryo 20-22hr    5 embryo 22-24hr    9 larva L1    7 larva L2    38 larva L3 12hr old    11 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    17 white prepupae 12hr    7 white prepupae 24hr    3 pupae 2d postWPP    266 pupae 3d postWPP    45 pupae 4d postWPP    12 adult male 01day    25 adult male 05day    30 adult male 30day    26 adult female 01day    14 adult female 05day    9 adult female 30day    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    6 embryo 10-12hr  (35) embryo 12-14hr  (123) embryo 14-16hr  (142) embryo 16-18hr  (48) embryo 18-20hr    24 embryo 20-22hr    5 embryo 22-24hr    9 larva L1    7 larva L2  (38) larva L3 12hr old    11 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    17 white prepupae 12hr    7 white prepupae 24hr    3 pupae 2d postWPP  (266) pupae 3d postWPP  (45) pupae 4d postWPP    12 adult male 01day    25 adult male 05day  (30) adult male 30day  26 adult female 01day    14 adult female 05day    9 adult female 30day    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    6 embryo 10-12hr    35 embryo 12-14hr  (123) embryo 14-16hr  (142) embryo 16-18hr    48 embryo 18-20hr    24 embryo 20-22hr    5 embryo 22-24hr    9 larva L1    7 larva L2    38 larva L3 12hr old    11 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    17 white prepupae 12hr    7 white prepupae 24hr    3 pupae 2d postWPP  (266) pupae 3d postWPP    45 pupae 4d postWPP    12 adult male 01day    25 adult male 05day    30 adult male 30day    26 adult female 01day    14 adult female 05day    9 adult female 30day    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    6 embryo 10-12hr    35 embryo 12-14hr    123 embryo 14-16hr    142 embryo 16-18hr    48 embryo 18-20hr    24 embryo 20-22hr    5 embryo 22-24hr    9 larva L1    7 larva L2    38 larva L3 12hr old    11 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    17 white prepupae 12hr    7 white prepupae 24hr    3 pupae 2d postWPP    266 pupae 3d postWPP    45 pupae 4d postWPP    12 adult male 01day    25 adult male 05day    30 adult male 30day    26 adult female 01day    14 adult female 05day    9 adult female 30day    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    6 embryo 10-12hr    35 embryo 12-14hr    123 embryo 14-16hr    142 embryo 16-18hr    48 embryo 18-20hr    24 embryo 20-22hr    5 embryo 22-24hr    9 larva L1    7 larva L2    38 larva L3 12hr old    11 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    17 white prepupae 12hr    7 white prepupae 24hr    3 pupae 2d postWPP    266 pupae 3d postWPP    45 pupae 4d postWPP    12 adult male 01day    25 adult male 05day    30 adult male 30day    26 adult female 01day    14 adult female 05day    9 adult female 30day    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    6 embryo 10-12hr  (35) embryo 12-14hr  (123) embryo 14-16hr  (142) embryo 16-18hr  (48) embryo 18-20hr    24 embryo 20-22hr    5 embryo 22-24hr    9 larva L1    7 larva L2  (38) larva L3 12hr old    11 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    17 white prepupae 12hr    7 white prepupae 24hr    3 pupae 2d postWPP  (266) pupae 3d postWPP  (45) pupae 4d postWPP    12 adult male 01day    25 adult male 05day  30 adult male 30day  26 adult female 01day    14 adult female 05day    9 adult female 30day    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    6 embryo 10-12hr    35 embryo 12-14hr  123 embryo 14-16hr  142 embryo 16-18hr    48 embryo 18-20hr    24 embryo 20-22hr    5 embryo 22-24hr    9 larva L1    7 larva L2    38 larva L3 12hr old    11 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    17 white prepupae 12hr    7 white prepupae 24hr    3 pupae 2d postWPP  (266) pupae 3d postWPP    45 pupae 4d postWPP    12 adult male 01day    25 adult male 05day    30 adult male 30day    26 adult female 01day    14 adult female 05day    9 adult female 30day    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    6 embryo 10-12hr    35 embryo 12-14hr    123 embryo 14-16hr    142 embryo 16-18hr    48 embryo 18-20hr    24 embryo 20-22hr    5 embryo 22-24hr    9 larva L1    7 larva L2    38 larva L3 12hr old    11 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    17 white prepupae 12hr    7 white prepupae 24hr    3 pupae 2d postWPP    266 pupae 3d postWPP    45 pupae 4d postWPP    12 adult male 01day    25 adult male 05day    30 adult male 30day    26 adult female 01day    14 adult female 05day    9 adult female 30day    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    65 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    32 embryonic Kc167    76 embryonic S1    74 embryonic S3    20 leg disc CME L1    43 wing disc CME-W2    17 wing disc ML-DmD8    7 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    44 wing disc ML-DmD21    5 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    32 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    61 ovary fGS/OSS    1 ovary OSC    0 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (65) Schneider line 2 Sg4  (47) embryonic 1182-4H  (52) embryonic GM2  (32) embryonic Kc167  (76) embryonic S1  (74) embryonic S3    20 leg disc CME L1  (43) wing disc CME-W2    17 wing disc ML-DmD8    7 wing disc ML-DmD9    7 wing disc ML-DmD16-c3  (44) wing disc ML-DmD21    5 wing disc ML-DmD32  (32) haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11  (32) antennal disc ML-DmD20-c5  (87) mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1  (28) CNS ML-DmBG2-c2  26 tumorous blood cells mbn2  (61) ovary fGS/OSS    1 ovary OSC    0 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    65 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    32 embryonic Kc167    76 embryonic S1    74 embryonic S3    20 leg disc CME L1    43 wing disc CME-W2    17 wing disc ML-DmD8    7 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    44 wing disc ML-DmD21    5 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    32 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    61 ovary fGS/OSS    1 ovary OSC    0 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    65 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    32 embryonic Kc167    76 embryonic S1    74 embryonic S3    20 leg disc CME L1    43 wing disc CME-W2    17 wing disc ML-DmD8    7 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    44 wing disc ML-DmD21    5 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    32 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    61 ovary fGS/OSS    1 ovary OSC    0 ovary OSS    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    65 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    32 embryonic Kc167    76 embryonic S1    74 embryonic S3    20 leg disc CME L1    43 wing disc CME-W2    17 wing disc ML-DmD8    7 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    44 wing disc ML-DmD21    5 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    32 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    61 ovary fGS/OSS    1 ovary OSC    0 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (65) Schneider line 2 Sg4  (47) embryonic 1182-4H  (52) embryonic GM2  32 embryonic Kc167  (76) embryonic S1  (74) embryonic S3    20 leg disc CME L1  (43) wing disc CME-W2    17 wing disc ML-DmD8    7 wing disc ML-DmD9    7 wing disc ML-DmD16-c3  (44) wing disc ML-DmD21    5 wing disc ML-DmD32  32 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11  32 antennal disc ML-DmD20-c5  (87) mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1  28 CNS ML-DmBG2-c2  26 tumorous blood cells mbn2  (61) ovary fGS/OSS    1 ovary OSC    0 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    65 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    32 embryonic Kc167    76 embryonic S1    74 embryonic S3    20 leg disc CME L1    43 wing disc CME-W2    17 wing disc ML-DmD8    7 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    44 wing disc ML-DmD21    5 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    32 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    61 ovary fGS/OSS    1 ovary OSC    0 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    65 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    32 embryonic Kc167    76 embryonic S1    74 embryonic S3    20 leg disc CME L1    43 wing disc CME-W2    17 wing disc ML-DmD8    7 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    44 wing disc ML-DmD21    5 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    32 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    28 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    61 ovary fGS/OSS    1 ovary OSC    0 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    9 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    33 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    9 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult  (33) Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult  (30) Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult  26 Paraquat 10 mM 48 hrs, 4-day adult  (28) Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    9 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    33 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    9 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    33 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    9 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    33 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    9 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult  (33) Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult  30 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult  26 Paraquat 10 mM 48 hrs, 4-day adult  28 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    9 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    33 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    9 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    33 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_09
External Data & Images
Linkouts	BDGP expression data • GH19356 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040600 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13631-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG13631 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG13631GD13036 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG13631 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG13631 Class Mutagen Stocks Known lesion CG13631GD13036 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6200 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13036} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{GT1}BG02218 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene_with_edited_transcript (Graveley et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG13631 - BthD anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - CG43444 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - CG5746 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - CG7049 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - CG7971 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - Ccs anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - Cg25C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - Clc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - Elongin-B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - Elongin-C anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG13631 - FK506-bp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - Fsn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - Jupiter anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - RpS19a anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - RpS21 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - RpS27A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - Rpb8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - SmD3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - mRpL52 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - skpA anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13631 - snama anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG13631 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 72526 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0040600 DroID - A comprehensive database of gene and protein interactions. • FBgn0040600 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 50073
Orthologs
OrthoDB Orthologs (13) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG61G3R2 Dipteran inclusive ortholog search EOG6Z36QJ Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG61G3R2)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG13631     Drosophila simulans   Dsim\GD21127 Y   Drosophila sechellia   Dsec\GM26623 Y   Drosophila erecta   Dere\GG11316 Y   Drosophila yakuba   Dyak\GE23512 Y   Drosophila ananassae   Dana\GF23046 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA12423 Y   Drosophila persimilis   Dper\GL13624 Y   Drosophila willistoni   Dwil\GK14036 Y   Drosophila virilis   Dvir\GJ23655 Y   Drosophila mojavensis   Dmoj\GI24025 Y   Drosophila grimshawi   Dgri\GH18448 Y
Orthologs in non-Drosophila Dipterans (EOG6Z36QJ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ008015
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD21127 Drosophila sechellia Dsec\GM26623 Drosophila erecta Dere\GG11316 Drosophila yakuba Dyak\GE23512 Drosophila ananassae Dana\GF23046 Drosophila pseudoobscura pseudoobscura Dpse\GA12423 Drosophila persimilis Dper\GL13624 Drosophila willistoni Dwil\GK14036 Drosophila virilis Dvir\GJ23655 Drosophila mojavensis Dmoj\GI24025 Drosophila grimshawi Dgri\GH18448
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v35680 w1118; P{GD13036}v35680 v35683 w1118; P{GD13036}v35683/TM3
Genomic Clones ( 1 )
	BACR33F18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 42 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH19356 RE41892 RE60943
Other clones	DPiM_GH19356
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP19120 RE28325 RE41821 RH24390 RH29540 RH37050 RH37053 RH37156 RH42603 RH46207 RH55115 RH59209 RH63486 RH64091
Other clones	17570 98077 101556 117919 190106 CK01.15B.F12 CK01.124D.G10 CK01.146D.E7 EK120520 EK123205 EK150006 EK178003 EK224111 EK228060 EK243416 EK245006 EK290260 EK291331 RP001007290 RP001013421 RP001022203 RP001024657 RP001041216 RP001049701
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0040600 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 50073
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG13631 BcDNA:GH19356 (BDGP Project Members, 2000-)
Additional comments
Other Comments
	Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. (Claridge-Chang et al., 2001)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143995 RefSeq (Proteins) • NP_652252 DDBJ / EMBL / GenBank • AAF56332 AAL28290 AI388438 AW940737 AY060742 Entrez Gene - A searchable database of RefSeq genes. • 50073 UniProtKB/TrEMBL • Q9VC43
Other Crossreferences
	BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH19356
Linkouts
	BioGRID - A database of protein and genetic interactions • 72526 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0040600 DroID - A comprehensive database of gene and protein interactions. • FBgn0040600 DRSC - Results from RNAi screens. • FBgn0040600 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040600 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13631-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0040600 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 50073 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 50073 modMine - Data generated by the modENCODE project. • FBgn0040600
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	BcDNA:GH19356   CG13631 (Rehwinkel et al., 2006, Woo et al., 2006)
Name Synonym
Secondary FlyBase IDs
	FBgn0064962
References ( 17 )
Research paper	Rehwinkel et al., 2006, Mol. Cell. Biol. 26(8): 2965--2975 Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster. [FBrf0191204] Woo et al., 2006, Mol. Cell 24(6): 967--976 Structural basis for protein recognition by B30.2/SPRY domains. [FBrf0193377] Claridge-Chang et al., 2001, Neuron 32(4): 657--671 Circadian regulation of gene expression systems in the Drosophila head. [FBrf0141689]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 29. Summary of A-to-I RNA Editing Sites Discovered. [FBrf0213715] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Review	Zdobnov et al., 2002, Science 298(5591): 149--159 Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster. [FBrf0152342]
Personal communication to FlyBase	Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]