Gene Dmel\CG16926

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General Information

Symbol

Dmel\CG16926

Species

D. melanogaster

Name

Annotation symbol

CG16926

Feature type

protein_coding_gene

FlyBase ID

FBgn0040732

Gene Model Status

Current

Stock availability

3 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

56D14-56D14

Sequence location

2R:15,387,800..15,388,828 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG16926 (FBgn0040732). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult heart, larval/adult fat body, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult crop, larval/adult hindgut, larval Malpighian tubules, larval salivary gland, larval trachea. Comments on Affy2 ProbeSet: ProbeSet 1625583_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG16926. Gene sequence location is 2R:15387800..15388828.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

56D14-56D14

Limits computationally determined from genome sequence between P{lacW}l(2)k00705^k00705&P{lacW}mei-W68^k05603 and P{EP}CG11007^EP736

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG16926 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.45

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG16926-RA

FBtr0086499

NM_144107

884

127

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG16926-PA

FBpp0085687

14.5

127

9.49

NP_652364

AAF57541

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q95RA0

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult heart, larval/adult fat body, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult crop, larval/adult hindgut, larval Malpighian tubules, larval salivary gland, larval trachea.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		2.475
Larval Midgut		15.9
Larval Hindgut		105.2
Larval Malpighian Tubules		213.3
Larval Fat Body		7532.1
Larval Salivary Gland		111.4
Larval Trachea		124.15
Larval Carcass		42.3
Adult Head		401.8
Adult Eye		80.375
Adult Brain		5
Adult Thoracic-Abdominal Ganglion		27.1
Adult Crop		103.6
Adult Midgut		21.4
Adult Hindgut		466.6
Adult Malpighian Tubules		49.4
Adult Fat Body		5029
Adult Salivary Gland		4.1
Adult Heart		4244.675
Adult VirginFemale Spermatheca		4931.7
Adult InseminatedFemale Spermatheca		4661.1
Adult Ovary		16.5
Adult Testis		8
Adult Male Accessory Gland		1.7
Adult Carcass		3802.2
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		2.475
Larval Midgut		15.9
Larval Hindgut		105.2
Larval Malpighian Tubules		213.3
Larval Fat Body		(7532.1)
Larval Salivary Gland		111.4
Larval Trachea		124.15
Larval Carcass		42.3
Adult Head		401.8
Adult Eye		80.375
Adult Brain		5
Adult Thoracic-Abdominal Ganglion		27.1
Adult Crop		103.6
Adult Midgut		21.4
Adult Hindgut		466.6
Adult Malpighian Tubules		49.4
Adult Fat Body		(5029)
Adult Salivary Gland		4.1
Adult Heart		(4244.675)
Adult VirginFemale Spermatheca		(4931.7)
Adult InseminatedFemale Spermatheca		(4661.1)
Adult Ovary		16.5
Adult Testis		8
Adult Male Accessory Gland		1.7
Adult Carcass		(3802.2)
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		2.475
Larval Midgut		15.9
Larval Hindgut		105.2
Larval Malpighian Tubules		213.3
Larval Fat Body		(7532.1)
Larval Salivary Gland		111.4
Larval Trachea		124.15
Larval Carcass		42.3
Adult Head		401.8
Adult Eye		80.375
Adult Brain		5
Adult Thoracic-Abdominal Ganglion		27.1
Adult Crop		103.6
Adult Midgut		21.4
Adult Hindgut		466.6
Adult Malpighian Tubules		49.4
Adult Fat Body		(5029)
Adult Salivary Gland		4.1
Adult Heart		(4244.675)
Adult VirginFemale Spermatheca		(4931.7)
Adult InseminatedFemale Spermatheca		(4661.1)
Adult Ovary		16.5
Adult Testis		8
Adult Male Accessory Gland		1.7
Adult Carcass		(3802.2)
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		2.475
Larval Midgut		15.9
Larval Hindgut		105.2
Larval Malpighian Tubules		213.3
Larval Fat Body		7532.1
Larval Salivary Gland		111.4
Larval Trachea		124.15
Larval Carcass		42.3
Adult Head		401.8
Adult Eye		80.375
Adult Brain		5
Adult Thoracic-Abdominal Ganglion		27.1
Adult Crop		103.6
Adult Midgut		21.4
Adult Hindgut		466.6
Adult Malpighian Tubules		49.4
Adult Fat Body		5029
Adult Salivary Gland		4.1
Adult Heart		4244.675
Adult VirginFemale Spermatheca		4931.7
Adult InseminatedFemale Spermatheca		4661.1
Adult Ovary		16.5
Adult Testis		8
Adult Male Accessory Gland		1.7
Adult Carcass		3802.2
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		2.475
Larval Midgut		15.9
Larval Hindgut		105.2
Larval Malpighian Tubules		213.3
Larval Fat Body		7532.1
Larval Salivary Gland		111.4
Larval Trachea		124.15
Larval Carcass		42.3
Adult Head		401.8
Adult Eye		80.375
Adult Brain		5
Adult Thoracic-Abdominal Ganglion		27.1
Adult Crop		103.6
Adult Midgut		21.4
Adult Hindgut		466.6
Adult Malpighian Tubules		49.4
Adult Fat Body		5029
Adult Salivary Gland		4.1
Adult Heart		4244.675
Adult VirginFemale Spermatheca		4931.7
Adult InseminatedFemale Spermatheca		4661.1
Adult Ovary		16.5
Adult Testis		8
Adult Male Accessory Gland		1.7
Adult Carcass		3802.2
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		2.475
Larval Midgut		15.9
Larval Hindgut		105.2
Larval Malpighian Tubules		213.3
Larval Fat Body		(7532.1)
Larval Salivary Gland		111.4
Larval Trachea		124.15
Larval Carcass		42.3
Adult Head		401.8
Adult Eye		80.375
Adult Brain		5
Adult Thoracic-Abdominal Ganglion		27.1
Adult Crop		103.6
Adult Midgut		21.4
Adult Hindgut		466.6
Adult Malpighian Tubules		49.4
Adult Fat Body		(5029)
Adult Salivary Gland		4.1
Adult Heart		(4244.675)
Adult VirginFemale Spermatheca		(4931.7)
Adult InseminatedFemale Spermatheca		(4661.1)
Adult Ovary		16.5
Adult Testis		8
Adult Male Accessory Gland		1.7
Adult Carcass		(3802.2)
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		2.475
Larval Midgut		15.9
Larval Hindgut		105.2
Larval Malpighian Tubules		213.3
Larval Fat Body		(7532.1)
Larval Salivary Gland		111.4
Larval Trachea		124.15
Larval Carcass		42.3
Adult Head		401.8
Adult Eye		80.375
Adult Brain		5
Adult Thoracic-Abdominal Ganglion		27.1
Adult Crop		103.6
Adult Midgut		21.4
Adult Hindgut		466.6
Adult Malpighian Tubules		49.4
Adult Fat Body		(5029)
Adult Salivary Gland		4.1
Adult Heart		(4244.675)
Adult VirginFemale Spermatheca		(4931.7)
Adult InseminatedFemale Spermatheca		(4661.1)
Adult Ovary		16.5
Adult Testis		8
Adult Male Accessory Gland		1.7
Adult Carcass		(3802.2)
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		2.475
Larval Midgut		15.9
Larval Hindgut		105.2
Larval Malpighian Tubules		213.3
Larval Fat Body		7532.1
Larval Salivary Gland		111.4
Larval Trachea		124.15
Larval Carcass		42.3
Adult Head		401.8
Adult Eye		80.375
Adult Brain		5
Adult Thoracic-Abdominal Ganglion		27.1
Adult Crop		103.6
Adult Midgut		21.4
Adult Hindgut		466.6
Adult Malpighian Tubules		49.4
Adult Fat Body		5029
Adult Salivary Gland		4.1
Adult Heart		4244.675
Adult VirginFemale Spermatheca		4931.7
Adult InseminatedFemale Spermatheca		4661.1
Adult Ovary		16.5
Adult Testis		8
Adult Male Accessory Gland		1.7
Adult Carcass		3802.2
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	401.8
NA	Eye	80.375
NA	Brain	5
2.475	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	no informative data
NA	Crop	103.6
no informative data	Midgut	no informative data
105.2	Hindgut	466.6
213.3	Malpighian Tubules	no informative data
7532.1	Fat Body	5029
111.4	Salivary Gland	4.1
NA	Heart	4244.675
124.15	Trachea	NA
NA	VirginFemale Spermatheca	4931.7
NA	InseminatedFemale Spermatheca	4661.1
NA	Ovary	16.5
NA	Testis	8
NA	Male Accessory Gland	1.7
no informative data	Carcass	3802.2

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		75
head, virgin 4-day female		89
head, virgin 20-day female		189
head, mated 1-day female		92
head, mated 4-day female		242
head, mated 20-day female		117
head, mated 1-day male		88
head, mated 4-day male		162
head, mated 20-day male		144
salivary gland, larvae L3 wandering		32
salivary gland, white prepupae		153
digestive system, larvae L3 wandering		68
digestive system, 1-day adult		44
digestive system, 4-day adult		52
digestive system, 20-day adult		37
fat body, larvae L3 wandering		907
fat body, white prepupae		1583
fat body, pupae P8		1068
carcass, larvae L3 wandering		42
carcass, 1-day adult		376
carcass, 4-day adult		512
carcass, 20-day adult		744
ovary, virgin 4-day female		3
ovary, mated 4-day female		0
testis, mated 4-day male		15
accessory gland, mated 4-day male		19
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		(75)
head, virgin 4-day female		(89)
head, virgin 20-day female		(189)
head, mated 1-day female		(92)
head, mated 4-day female		(242)
head, mated 20-day female		(117)
head, mated 1-day male		(88)
head, mated 4-day male		(162)
head, mated 20-day male		(144)
salivary gland, larvae L3 wandering		(32)
salivary gland, white prepupae		(153)
digestive system, larvae L3 wandering		(68)
digestive system, 1-day adult		(44)
digestive system, 4-day adult		(52)
digestive system, 20-day adult		(37)
fat body, larvae L3 wandering		(907)
fat body, white prepupae		(1583)
fat body, pupae P8		(1068)
carcass, larvae L3 wandering		(42)
carcass, 1-day adult		(376)
carcass, 4-day adult		(512)
carcass, 20-day adult		(744)
ovary, virgin 4-day female		3
ovary, mated 4-day female		0
testis, mated 4-day male		15
accessory gland, mated 4-day male		19
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		75
head, virgin 4-day female		89
head, virgin 20-day female		(189)
head, mated 1-day female		92
head, mated 4-day female		(242)
head, mated 20-day female		(117)
head, mated 1-day male		88
head, mated 4-day male		(162)
head, mated 20-day male		(144)
salivary gland, larvae L3 wandering		32
salivary gland, white prepupae		(153)
digestive system, larvae L3 wandering		68
digestive system, 1-day adult		44
digestive system, 4-day adult		52
digestive system, 20-day adult		37
fat body, larvae L3 wandering		(907)
fat body, white prepupae		(1583)
fat body, pupae P8		(1068)
carcass, larvae L3 wandering		42
carcass, 1-day adult		(376)
carcass, 4-day adult		(512)
carcass, 20-day adult		(744)
ovary, virgin 4-day female		3
ovary, mated 4-day female		0
testis, mated 4-day male		15
accessory gland, mated 4-day male		19
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		75
head, virgin 4-day female		89
head, virgin 20-day female		189
head, mated 1-day female		92
head, mated 4-day female		242
head, mated 20-day female		117
head, mated 1-day male		88
head, mated 4-day male		162
head, mated 20-day male		144
salivary gland, larvae L3 wandering		32
salivary gland, white prepupae		153
digestive system, larvae L3 wandering		68
digestive system, 1-day adult		44
digestive system, 4-day adult		52
digestive system, 20-day adult		37
fat body, larvae L3 wandering		907
fat body, white prepupae		1583
fat body, pupae P8		1068
carcass, larvae L3 wandering		42
carcass, 1-day adult		376
carcass, 4-day adult		512
carcass, 20-day adult		744
ovary, virgin 4-day female		3
ovary, mated 4-day female		0
testis, mated 4-day male		15
accessory gland, mated 4-day male		19
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		75
head, virgin 4-day female		89
head, virgin 20-day female		189
head, mated 1-day female		92
head, mated 4-day female		242
head, mated 20-day female		117
head, mated 1-day male		88
head, mated 4-day male		162
head, mated 20-day male		144
salivary gland, larvae L3 wandering		32
salivary gland, white prepupae		153
digestive system, larvae L3 wandering		68
digestive system, 1-day adult		44
digestive system, 4-day adult		52
digestive system, 20-day adult		37
fat body, larvae L3 wandering		907
fat body, white prepupae		1583
fat body, pupae P8		1068
carcass, larvae L3 wandering		42
carcass, 1-day adult		376
carcass, 4-day adult		512
carcass, 20-day adult		744
ovary, virgin 4-day female		3
ovary, mated 4-day female		0
testis, mated 4-day male		15
accessory gland, mated 4-day male		19
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		(75)
head, virgin 4-day female		(89)
head, virgin 20-day female		(189)
head, mated 1-day female		(92)
head, mated 4-day female		(242)
head, mated 20-day female		(117)
head, mated 1-day male		(88)
head, mated 4-day male		(162)
head, mated 20-day male		(144)
salivary gland, larvae L3 wandering		32
salivary gland, white prepupae		(153)
digestive system, larvae L3 wandering		(68)
digestive system, 1-day adult		(44)
digestive system, 4-day adult		(52)
digestive system, 20-day adult		(37)
fat body, larvae L3 wandering		(907)
fat body, white prepupae		(1583)
fat body, pupae P8		(1068)
carcass, larvae L3 wandering		(42)
carcass, 1-day adult		(376)
carcass, 4-day adult		(512)
carcass, 20-day adult		(744)
ovary, virgin 4-day female		3
ovary, mated 4-day female		0
testis, mated 4-day male		15
accessory gland, mated 4-day male		19
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		75
head, virgin 4-day female		89
head, virgin 20-day female		(189)
head, mated 1-day female		92
head, mated 4-day female		(242)
head, mated 20-day female		117
head, mated 1-day male		88
head, mated 4-day male		(162)
head, mated 20-day male		(144)
salivary gland, larvae L3 wandering		32
salivary gland, white prepupae		(153)
digestive system, larvae L3 wandering		68
digestive system, 1-day adult		44
digestive system, 4-day adult		52
digestive system, 20-day adult		37
fat body, larvae L3 wandering		(907)
fat body, white prepupae		(1583)
fat body, pupae P8		(1068)
carcass, larvae L3 wandering		42
carcass, 1-day adult		(376)
carcass, 4-day adult		(512)
carcass, 20-day adult		(744)
ovary, virgin 4-day female		3
ovary, mated 4-day female		0
testis, mated 4-day male		15
accessory gland, mated 4-day male		19
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		75
head, virgin 4-day female		89
head, virgin 20-day female		189
head, mated 1-day female		92
head, mated 4-day female		242
head, mated 20-day female		117
head, mated 1-day male		88
head, mated 4-day male		162
head, mated 20-day male		144
salivary gland, larvae L3 wandering		32
salivary gland, white prepupae		153
digestive system, larvae L3 wandering		68
digestive system, 1-day adult		44
digestive system, 4-day adult		52
digestive system, 20-day adult		37
fat body, larvae L3 wandering		907
fat body, white prepupae		1583
fat body, pupae P8		1068
carcass, larvae L3 wandering		42
carcass, 1-day adult		376
carcass, 4-day adult		512
carcass, 20-day adult		744
ovary, virgin 4-day female		3
ovary, mated 4-day female		0
testis, mated 4-day male		15
accessory gland, mated 4-day male		19
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		1
embryo 06-08hr		1
embryo 08-10hr		2
embryo 10-12hr		2
embryo 12-14hr		5
embryo 14-16hr		13
embryo 16-18hr		30
embryo 18-20hr		57
embryo 20-22hr		42
embryo 22-24hr		50
larva L1		27
larva L2		34
larva L3 12hr old		102
larva L3 puffstage 1-2		282
larva L3 puffstage 3-6		221
larva L3 puffstage 7-9		305
white prepupae new		501
white prepupae 12hr		1232
white prepupae 24hr		389
pupae 2d postWPP		508
pupae 3d postWPP		212
pupae 4d postWPP		297
adult male 01day		137
adult male 05day		135
adult male 30day		92
adult female 01day		64
adult female 05day		49
adult female 30day		68
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		1
embryo 06-08hr		1
embryo 08-10hr		2
embryo 10-12hr		2
embryo 12-14hr		5
embryo 14-16hr		13
embryo 16-18hr		(30)
embryo 18-20hr		(57)
embryo 20-22hr		(42)
embryo 22-24hr		(50)
larva L1		(27)
larva L2		(34)
larva L3 12hr old		(102)
larva L3 puffstage 1-2		(282)
larva L3 puffstage 3-6		(221)
larva L3 puffstage 7-9		(305)
white prepupae new		(501)
white prepupae 12hr		(1232)
white prepupae 24hr		(389)
pupae 2d postWPP		(508)
pupae 3d postWPP		(212)
pupae 4d postWPP		(297)
adult male 01day		(137)
adult male 05day		(135)
adult male 30day		(92)
adult female 01day		(64)
adult female 05day		(49)
adult female 30day		(68)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		1
embryo 06-08hr		1
embryo 08-10hr		2
embryo 10-12hr		2
embryo 12-14hr		5
embryo 14-16hr		13
embryo 16-18hr		30
embryo 18-20hr		57
embryo 20-22hr		42
embryo 22-24hr		50
larva L1		27
larva L2		34
larva L3 12hr old		102
larva L3 puffstage 1-2		(282)
larva L3 puffstage 3-6		(221)
larva L3 puffstage 7-9		(305)
white prepupae new		(501)
white prepupae 12hr		(1232)
white prepupae 24hr		(389)
pupae 2d postWPP		(508)
pupae 3d postWPP		(212)
pupae 4d postWPP		(297)
adult male 01day		(137)
adult male 05day		(135)
adult male 30day		92
adult female 01day		64
adult female 05day		49
adult female 30day		68
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		1
embryo 06-08hr		1
embryo 08-10hr		2
embryo 10-12hr		2
embryo 12-14hr		5
embryo 14-16hr		13
embryo 16-18hr		30
embryo 18-20hr		57
embryo 20-22hr		42
embryo 22-24hr		50
larva L1		27
larva L2		34
larva L3 12hr old		102
larva L3 puffstage 1-2		282
larva L3 puffstage 3-6		221
larva L3 puffstage 7-9		305
white prepupae new		501
white prepupae 12hr		1232
white prepupae 24hr		389
pupae 2d postWPP		508
pupae 3d postWPP		212
pupae 4d postWPP		297
adult male 01day		137
adult male 05day		135
adult male 30day		92
adult female 01day		64
adult female 05day		49
adult female 30day		68
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		1
embryo 06-08hr		1
embryo 08-10hr		2
embryo 10-12hr		2
embryo 12-14hr		5
embryo 14-16hr		13
embryo 16-18hr		30
embryo 18-20hr		57
embryo 20-22hr		42
embryo 22-24hr		50
larva L1		27
larva L2		34
larva L3 12hr old		102
larva L3 puffstage 1-2		282
larva L3 puffstage 3-6		221
larva L3 puffstage 7-9		305
white prepupae new		501
white prepupae 12hr		1232
white prepupae 24hr		389
pupae 2d postWPP		508
pupae 3d postWPP		212
pupae 4d postWPP		297
adult male 01day		137
adult male 05day		135
adult male 30day		92
adult female 01day		64
adult female 05day		49
adult female 30day		68
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		1
embryo 06-08hr		1
embryo 08-10hr		2
embryo 10-12hr		2
embryo 12-14hr		5
embryo 14-16hr		13
embryo 16-18hr		30
embryo 18-20hr		(57)
embryo 20-22hr		(42)
embryo 22-24hr		(50)
larva L1		27
larva L2		(34)
larva L3 12hr old		(102)
larva L3 puffstage 1-2		(282)
larva L3 puffstage 3-6		(221)
larva L3 puffstage 7-9		(305)
white prepupae new		(501)
white prepupae 12hr		(1232)
white prepupae 24hr		(389)
pupae 2d postWPP		(508)
pupae 3d postWPP		(212)
pupae 4d postWPP		(297)
adult male 01day		(137)
adult male 05day		(135)
adult male 30day		(92)
adult female 01day		(64)
adult female 05day		(49)
adult female 30day		(68)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		1
embryo 06-08hr		1
embryo 08-10hr		2
embryo 10-12hr		2
embryo 12-14hr		5
embryo 14-16hr		13
embryo 16-18hr		30
embryo 18-20hr		57
embryo 20-22hr		42
embryo 22-24hr		50
larva L1		27
larva L2		34
larva L3 12hr old		102
larva L3 puffstage 1-2		(282)
larva L3 puffstage 3-6		(221)
larva L3 puffstage 7-9		(305)
white prepupae new		(501)
white prepupae 12hr		(1232)
white prepupae 24hr		(389)
pupae 2d postWPP		(508)
pupae 3d postWPP		(212)
pupae 4d postWPP		(297)
adult male 01day		137
adult male 05day		135
adult male 30day		92
adult female 01day		64
adult female 05day		49
adult female 30day		68
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		1
embryo 06-08hr		1
embryo 08-10hr		2
embryo 10-12hr		2
embryo 12-14hr		5
embryo 14-16hr		13
embryo 16-18hr		30
embryo 18-20hr		57
embryo 20-22hr		42
embryo 22-24hr		50
larva L1		27
larva L2		34
larva L3 12hr old		102
larva L3 puffstage 1-2		282
larva L3 puffstage 3-6		221
larva L3 puffstage 7-9		305
white prepupae new		501
white prepupae 12hr		1232
white prepupae 24hr		389
pupae 2d postWPP		508
pupae 3d postWPP		212
pupae 4d postWPP		297
adult male 01day		137
adult male 05day		135
adult male 30day		92
adult female 01day		64
adult female 05day		49
adult female 30day		68
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		0
leg disc CME L1		1
wing disc CME-W2		25
wing disc ML-DmD8		0
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		0
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		1
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		0
leg disc CME L1		1
wing disc CME-W2		25
wing disc ML-DmD8		0
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		0
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		1
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		0
leg disc CME L1		1
wing disc CME-W2		25
wing disc ML-DmD8		0
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		0
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		1
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		0
leg disc CME L1		1
wing disc CME-W2		25
wing disc ML-DmD8		0
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		0
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		1
ovary OSC		0
ovary OSS		0
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		0
leg disc CME L1		1
wing disc CME-W2		25
wing disc ML-DmD8		0
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		0
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		1
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		0
leg disc CME L1		1
wing disc CME-W2		25
wing disc ML-DmD8		0
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		0
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		1
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		0
leg disc CME L1		1
wing disc CME-W2		25
wing disc ML-DmD8		0
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		0
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		1
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		0
leg disc CME L1		1
wing disc CME-W2		25
wing disc ML-DmD8		0
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		0
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		1
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		122
cold shock, 4-day adult		110
heat shock, 4-day adult		144
Cadmium 50 mM 6 hrs, larvae L3		146
Cadmium 50 mM 12 hrs, larvae L3		308
Cadmium 50 mM 48 hrs, 4-day adult		81
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		103
Copper 15 mM 48 hrs, 4-day adult		51
Zinc 5 mM 12 hrs, larvae L3		75
Zinc 4.5 mM 48 hrs, 4-day adult		71
Ethanol 2.5% 3 hrs, larvae L3		80
Ethanol 5% 3 hrs, larvae L3		253
Ethanol 10% 3 hrs, larvae L3		152
Caffeine 1.5 mg/ml 4 hrs, larvae L3		226
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		124
Caffeine 25 mg/ml 48 hrs, 4-day adult		103
Paraquat 5 mM 48 hrs, 4-day adult		210
Paraquat 10 mM 48 hrs, 4-day adult		163
Rotenone 2 μg 12 hrs, larvae L3		154
Rotenone 8 μg 12 hrs, larvae L3		129
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(122)
cold shock, 4-day adult		(110)
heat shock, 4-day adult		(144)
Cadmium 50 mM 6 hrs, larvae L3		(146)
Cadmium 50 mM 12 hrs, larvae L3		(308)
Cadmium 50 mM 48 hrs, 4-day adult		(81)
Cadmium 100 mM 48 hrs, 4-day adult		(37)
Copper 0.5 mM 12 hrs, larvae L3		(103)
Copper 15 mM 48 hrs, 4-day adult		(51)
Zinc 5 mM 12 hrs, larvae L3		(75)
Zinc 4.5 mM 48 hrs, 4-day adult		(71)
Ethanol 2.5% 3 hrs, larvae L3		(80)
Ethanol 5% 3 hrs, larvae L3		(253)
Ethanol 10% 3 hrs, larvae L3		(152)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(226)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(124)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(103)
Paraquat 5 mM 48 hrs, 4-day adult		(210)
Paraquat 10 mM 48 hrs, 4-day adult		(163)
Rotenone 2 μg 12 hrs, larvae L3		(154)
Rotenone 8 μg 12 hrs, larvae L3		(129)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		(122)
cold shock, 4-day adult		(110)
heat shock, 4-day adult		(144)
Cadmium 50 mM 6 hrs, larvae L3		(146)
Cadmium 50 mM 12 hrs, larvae L3		(308)
Cadmium 50 mM 48 hrs, 4-day adult		81
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		103
Copper 15 mM 48 hrs, 4-day adult		51
Zinc 5 mM 12 hrs, larvae L3		75
Zinc 4.5 mM 48 hrs, 4-day adult		71
Ethanol 2.5% 3 hrs, larvae L3		80
Ethanol 5% 3 hrs, larvae L3		(253)
Ethanol 10% 3 hrs, larvae L3		(152)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(226)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(124)
Caffeine 25 mg/ml 48 hrs, 4-day adult		103
Paraquat 5 mM 48 hrs, 4-day adult		(210)
Paraquat 10 mM 48 hrs, 4-day adult		(163)
Rotenone 2 μg 12 hrs, larvae L3		(154)
Rotenone 8 μg 12 hrs, larvae L3		(129)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		122
cold shock, 4-day adult		110
heat shock, 4-day adult		144
Cadmium 50 mM 6 hrs, larvae L3		146
Cadmium 50 mM 12 hrs, larvae L3		308
Cadmium 50 mM 48 hrs, 4-day adult		81
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		103
Copper 15 mM 48 hrs, 4-day adult		51
Zinc 5 mM 12 hrs, larvae L3		75
Zinc 4.5 mM 48 hrs, 4-day adult		71
Ethanol 2.5% 3 hrs, larvae L3		80
Ethanol 5% 3 hrs, larvae L3		253
Ethanol 10% 3 hrs, larvae L3		152
Caffeine 1.5 mg/ml 4 hrs, larvae L3		226
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		124
Caffeine 25 mg/ml 48 hrs, 4-day adult		103
Paraquat 5 mM 48 hrs, 4-day adult		210
Paraquat 10 mM 48 hrs, 4-day adult		163
Rotenone 2 μg 12 hrs, larvae L3		154
Rotenone 8 μg 12 hrs, larvae L3		129
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		122
cold shock, 4-day adult		110
heat shock, 4-day adult		144
Cadmium 50 mM 6 hrs, larvae L3		146
Cadmium 50 mM 12 hrs, larvae L3		308
Cadmium 50 mM 48 hrs, 4-day adult		81
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		103
Copper 15 mM 48 hrs, 4-day adult		51
Zinc 5 mM 12 hrs, larvae L3		75
Zinc 4.5 mM 48 hrs, 4-day adult		71
Ethanol 2.5% 3 hrs, larvae L3		80
Ethanol 5% 3 hrs, larvae L3		253
Ethanol 10% 3 hrs, larvae L3		152
Caffeine 1.5 mg/ml 4 hrs, larvae L3		226
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		124
Caffeine 25 mg/ml 48 hrs, 4-day adult		103
Paraquat 5 mM 48 hrs, 4-day adult		210
Paraquat 10 mM 48 hrs, 4-day adult		163
Rotenone 2 μg 12 hrs, larvae L3		154
Rotenone 8 μg 12 hrs, larvae L3		129
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(122)
cold shock, 4-day adult		(110)
heat shock, 4-day adult		(144)
Cadmium 50 mM 6 hrs, larvae L3		(146)
Cadmium 50 mM 12 hrs, larvae L3		(308)
Cadmium 50 mM 48 hrs, 4-day adult		(81)
Cadmium 100 mM 48 hrs, 4-day adult		(37)
Copper 0.5 mM 12 hrs, larvae L3		(103)
Copper 15 mM 48 hrs, 4-day adult		(51)
Zinc 5 mM 12 hrs, larvae L3		(75)
Zinc 4.5 mM 48 hrs, 4-day adult		(71)
Ethanol 2.5% 3 hrs, larvae L3		(80)
Ethanol 5% 3 hrs, larvae L3		(253)
Ethanol 10% 3 hrs, larvae L3		(152)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(226)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(124)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(103)
Paraquat 5 mM 48 hrs, 4-day adult		(210)
Paraquat 10 mM 48 hrs, 4-day adult		(163)
Rotenone 2 μg 12 hrs, larvae L3		(154)
Rotenone 8 μg 12 hrs, larvae L3		(129)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		122
cold shock, 4-day adult		110
heat shock, 4-day adult		(144)
Cadmium 50 mM 6 hrs, larvae L3		(146)
Cadmium 50 mM 12 hrs, larvae L3		(308)
Cadmium 50 mM 48 hrs, 4-day adult		81
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		103
Copper 15 mM 48 hrs, 4-day adult		51
Zinc 5 mM 12 hrs, larvae L3		75
Zinc 4.5 mM 48 hrs, 4-day adult		71
Ethanol 2.5% 3 hrs, larvae L3		80
Ethanol 5% 3 hrs, larvae L3		(253)
Ethanol 10% 3 hrs, larvae L3		(152)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(226)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		124
Caffeine 25 mg/ml 48 hrs, 4-day adult		103
Paraquat 5 mM 48 hrs, 4-day adult		(210)
Paraquat 10 mM 48 hrs, 4-day adult		(163)
Rotenone 2 μg 12 hrs, larvae L3		(154)
Rotenone 8 μg 12 hrs, larvae L3		129
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		122
cold shock, 4-day adult		110
heat shock, 4-day adult		144
Cadmium 50 mM 6 hrs, larvae L3		146
Cadmium 50 mM 12 hrs, larvae L3		308
Cadmium 50 mM 48 hrs, 4-day adult		81
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		103
Copper 15 mM 48 hrs, 4-day adult		51
Zinc 5 mM 12 hrs, larvae L3		75
Zinc 4.5 mM 48 hrs, 4-day adult		71
Ethanol 2.5% 3 hrs, larvae L3		80
Ethanol 5% 3 hrs, larvae L3		253
Ethanol 10% 3 hrs, larvae L3		152
Caffeine 1.5 mg/ml 4 hrs, larvae L3		226
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		124
Caffeine 25 mg/ml 48 hrs, 4-day adult		103
Paraquat 5 mM 48 hrs, 4-day adult		210
Paraquat 10 mM 48 hrs, 4-day adult		163
Rotenone 2 μg 12 hrs, larvae L3		154
Rotenone 8 μg 12 hrs, larvae L3		129
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

LP01766

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0040732

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG16926-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG16926^GD8594

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG16926	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG16926	Class	Mutagen	Stocks	Known lesion
CG16926^GD8594		in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG16926^KK112305		in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD8594}

P{KK112305}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

PBac{PB}CG15120^c01671

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG16926 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

72587

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0040732

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

50205

Orthologs

OrthoDB Orthologs (27) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG605SMT

Dipteran inclusive ortholog search

EOG6FFDB9

Insect inclusive ortholog search

EOG6893J7

Arthropod inclusive ortholog search

EOG634TPT

Metazoa inclusive ortholog search

No orthologs identified

Orthologs in Drosophila Species (EOG605SMT)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA24253

Drosophila persimilis

Dper\GL21299

Drosophila willistoni

Dwil\GK15702

Drosophila willistoni

Dwil\GK24044

Drosophila virilis

Dvir\GJ21418

Drosophila mojavensis

Dmoj\GI20568

Drosophila grimshawi

Dgri\GH22771

Orthologs in non-Drosophila Dipterans (EOG6FFDB9)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL005474

Anopheles gambiae

Malaria mosquito

Agam\AGAP011317

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ019270

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ018116

Orthologs in non-Dipteran Insects (EOG6893J7)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB47029

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG018532

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH19602

Atta cephalotes

Leafcutter ant

Acep\ACEP12571

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO23502

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL20955

Linepithema humile

Argentine ant

Lhum\LH21595

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB16230

Bombyx mori

Silkmoth

Bmor\BGIBMGA009001

Tribolium castaneum

Red flour beetle

Tcas\TC005881

Orthologs in non-Insect Arthropods (None identified)

No non-Insect Arthropod orthologies identified

Orthologs in non-Arthropod Metazoa (None identified)

No non-Arthropod Metazoa orthologies identified

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA24253

Drosophila persimilis

Dper\GL21299

Drosophila willistoni

Dwil\GK15702

Drosophila virilis

Dvir\GJ21418

Drosophila mojavensis

Dmoj\GI20568

Drosophila grimshawi

Dgri\GH22771

Stocks & Reagents

Stocks Listed in FlyBase ( 3 )

VDRC

v103504

P{KK112305}VIE-260B

v39881

w¹¹¹⁸; P{GD8594}v39881

v39882

w¹¹¹⁸; P{GD8594}v39882

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 39 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

LP01766

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0040732

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

50205

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_144107

RefSeq (Proteins)

•

NP_652364

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

50205

UniProtKB/TrEMBL

•

Q95RA0

Other Crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

LP01766

Linkouts

BioGRID - A database of protein and genetic interactions

•

72587

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0040732

DRSC - Results from RNAi screens.

•

FBgn0040732

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0040732

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG16926-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0040732

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

50205

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

50205

modMine - Data generated by the modENCODE project.

•

FBgn0040732

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

141315_at

(Kristensen et al., 2005)

CG16926

(Ayres et al., 2008, Roxstrom-Lindquist et al., 2004, Keleman et al., 2009.8.5, Kohn et al., 2008)

Name Synonym

Secondary FlyBase IDs

References ( 13 )

Research paper

Ayres et al., 2008, Genetics 178(3): 1807--1815: Identification of Drosophila mutants altering defense of and endurance to Listeria monocytogenes infection. [FBrf0205079]
Kohn et al., 2008, Genes & Genet. Systems 83(3): 265--273: Decoupled differentiation of gene expression and coding sequence among Drosophila populations. [FBrf0205848]
Kristensen et al., 2005, Genetics 171(1): 157--167: Genome-wide analysis on inbreeding effects on gene expression in Drosophila melanogaster. [FBrf0187643]
Roxstrom-Lindquist et al., 2004, EMBO Rep. 5(2): 207--212: Parasite-specific immune response in adult Drosophila melanogaster: a genomic study. [FBrf0167559]

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Gene Disruption Project members, 2001-, (Computer file): (Computer file) [FBrf0132177]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file): Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]