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Gene Dmel\CG13779

General Information
Symbol	Dmel\CG13779	Species	D. melanogaster
Name		Annotation symbol	CG13779
Feature type	protein_coding_gene	FlyBase ID	FBgn0040954
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	27D7-27D7	Sequence location	2L:7,063,985..7,064,467 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG13779 (FBgn0040954). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: peptidase activity. There is experimental evidence that it is involved in the biological process: neurogenesis. 5 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: DSS1/SEM1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult central nervous system, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1640352_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG13779. Gene sequence location is 2L:7063985..7064467.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features BKN32693 HFA02282 BKN46047
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 27D7-27D7   Limits computationally determined from genome sequence between P{PZ}snRNP70K02107 and P{PZ}wg02657
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG13779 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG13779-RA FBtr0079403  NM_144298   428   79
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG13779-PA   FBpp0079031   9.4   79   3.70     NP_652555   AAF52481
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • DSS1/SEM1 (IPR007834)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF52481   AY070697 AAL48168   BE977666   BI563735   BI568962   BI568963   BI569067   BI569068   BI569198   BI569199   BI569277   BI569278   BI583915   BI586141   BI588855   BI590090   BI590301   BI593529   BI630440   CK134762   CO183435   CO338715   CZ467329   EC263540   EV575890   EV583939   EV584056   EV585406   EV587249   EV590524   EV593267   GH942115   GH943536   GH944528   GH944838   GH946433   GH947565   GH947986   GH952682   GH954224   GH955201   GH955246   GH955717   GH969539   GH970835   GH978941   GH978954   GH981458   GH984672
UniProtKB/Swiss-Prot	Q9VM46
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0040954    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0040954 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0040954 expression level Developmental Stage   Expression Level embryo 00-02hr    14849 embryo 02-04hr    2899 embryo 04-06hr    8673 embryo 06-08hr    8979 embryo 08-10hr    6699 embryo 10-12hr    4773 embryo 12-14hr    4847 embryo 14-16hr    2443 embryo 16-18hr    2462 embryo 18-20hr    1848 embryo 20-22hr    2085 embryo 22-24hr    2515 larva L1    4217 larva L2    10394 larva L3 12hr old    5849 larva L3 puffstage 1-2    11409 larva L3 puffstage 3-6    20171 larva L3 puffstage 7-9    32064 white prepupae new    37753 white prepupae 12hr    18666 white prepupae 24hr    16445 pupae 2d postWPP    12399 pupae 3d postWPP    8629 pupae 4d postWPP    9137 adult male 01day    7978 adult male 05day    5732 adult male 30day    5301 adult female 01day    7970 adult female 05day    16427 adult female 30day    13816 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (14849) embryo 02-04hr  (2899) embryo 04-06hr  (8673) embryo 06-08hr  (8979) embryo 08-10hr  (6699) embryo 10-12hr  (4773) embryo 12-14hr  (4847) embryo 14-16hr  (2443) embryo 16-18hr  (2462) embryo 18-20hr  (1848) embryo 20-22hr  (2085) embryo 22-24hr  (2515) larva L1  (4217) larva L2  (10394) larva L3 12hr old  (5849) larva L3 puffstage 1-2  (11409) larva L3 puffstage 3-6  (20171) larva L3 puffstage 7-9  (32064) white prepupae new  (37753) white prepupae 12hr  (18666) white prepupae 24hr  (16445) pupae 2d postWPP  (12399) pupae 3d postWPP  (8629) pupae 4d postWPP  (9137) adult male 01day  (7978) adult male 05day  (5732) adult male 30day  (5301) adult female 01day  (7970) adult female 05day  (16427) adult female 30day  (13816) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (14849) embryo 02-04hr  (2899) embryo 04-06hr  (8673) embryo 06-08hr  (8979) embryo 08-10hr  (6699) embryo 10-12hr  (4773) embryo 12-14hr  (4847) embryo 14-16hr  (2443) embryo 16-18hr  (2462) embryo 18-20hr  (1848) embryo 20-22hr  (2085) embryo 22-24hr  (2515) larva L1  (4217) larva L2  (10394) larva L3 12hr old  (5849) larva L3 puffstage 1-2  (11409) larva L3 puffstage 3-6  (20171) larva L3 puffstage 7-9  (32064) white prepupae new  (37753) white prepupae 12hr  (18666) white prepupae 24hr  (16445) pupae 2d postWPP  (12399) pupae 3d postWPP  (8629) pupae 4d postWPP  (9137) adult male 01day  (7978) adult male 05day  (5732) adult male 30day  (5301) adult female 01day  (7970) adult female 05day  (16427) adult female 30day  (13816) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (14849) embryo 02-04hr    2899 embryo 04-06hr    8673 embryo 06-08hr    8979 embryo 08-10hr    6699 embryo 10-12hr    4773 embryo 12-14hr    4847 embryo 14-16hr    2443 embryo 16-18hr    2462 embryo 18-20hr    1848 embryo 20-22hr    2085 embryo 22-24hr    2515 larva L1    4217 larva L2  10394 larva L3 12hr old    5849 larva L3 puffstage 1-2  (11409) larva L3 puffstage 3-6  (20171) larva L3 puffstage 7-9  (32064) white prepupae new  (37753) white prepupae 12hr  (18666) white prepupae 24hr  (16445) pupae 2d postWPP  (12399) pupae 3d postWPP    8629 pupae 4d postWPP    9137 adult male 01day    7978 adult male 05day    5732 adult male 30day    5301 adult female 01day    7970 adult female 05day  (16427) adult female 30day  (13816) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    14849 embryo 02-04hr    2899 embryo 04-06hr    8673 embryo 06-08hr    8979 embryo 08-10hr    6699 embryo 10-12hr    4773 embryo 12-14hr    4847 embryo 14-16hr    2443 embryo 16-18hr    2462 embryo 18-20hr    1848 embryo 20-22hr    2085 embryo 22-24hr    2515 larva L1    4217 larva L2    10394 larva L3 12hr old    5849 larva L3 puffstage 1-2    11409 larva L3 puffstage 3-6    20171 larva L3 puffstage 7-9    32064 white prepupae new    37753 white prepupae 12hr    18666 white prepupae 24hr    16445 pupae 2d postWPP    12399 pupae 3d postWPP    8629 pupae 4d postWPP    9137 adult male 01day    7978 adult male 05day    5732 adult male 30day    5301 adult female 01day    7970 adult female 05day    16427 adult female 30day    13816 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0040954 expression level Developmental Stage   Expression Level embryo 00-02hr    14849 embryo 02-04hr    2899 embryo 04-06hr    8673 embryo 06-08hr    8979 embryo 08-10hr    6699 embryo 10-12hr    4773 embryo 12-14hr    4847 embryo 14-16hr    2443 embryo 16-18hr    2462 embryo 18-20hr    1848 embryo 20-22hr    2085 embryo 22-24hr    2515 larva L1    4217 larva L2    10394 larva L3 12hr old    5849 larva L3 puffstage 1-2    11409 larva L3 puffstage 3-6    20171 larva L3 puffstage 7-9    32064 white prepupae new    37753 white prepupae 12hr    18666 white prepupae 24hr    16445 pupae 2d postWPP    12399 pupae 3d postWPP    8629 pupae 4d postWPP    9137 adult male 01day    7978 adult male 05day    5732 adult male 30day    5301 adult female 01day    7970 adult female 05day    16427 adult female 30day    13816 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (14849) embryo 02-04hr  (2899) embryo 04-06hr  (8673) embryo 06-08hr  (8979) embryo 08-10hr  (6699) embryo 10-12hr  (4773) embryo 12-14hr  (4847) embryo 14-16hr  (2443) embryo 16-18hr  (2462) embryo 18-20hr  (1848) embryo 20-22hr  (2085) embryo 22-24hr  (2515) larva L1  (4217) larva L2  (10394) larva L3 12hr old  (5849) larva L3 puffstage 1-2  (11409) larva L3 puffstage 3-6  (20171) larva L3 puffstage 7-9  (32064) white prepupae new  (37753) white prepupae 12hr  (18666) white prepupae 24hr  (16445) pupae 2d postWPP  (12399) pupae 3d postWPP  (8629) pupae 4d postWPP  (9137) adult male 01day  (7978) adult male 05day  (5732) adult male 30day  (5301) adult female 01day  (7970) adult female 05day  (16427) adult female 30day  (13816) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (14849) embryo 02-04hr  (2899) embryo 04-06hr  (8673) embryo 06-08hr  (8979) embryo 08-10hr  (6699) embryo 10-12hr  (4773) embryo 12-14hr  (4847) embryo 14-16hr  2443 embryo 16-18hr  2462 embryo 18-20hr  1848 embryo 20-22hr  2085 embryo 22-24hr  (2515) larva L1  (4217) larva L2  (10394) larva L3 12hr old  (5849) larva L3 puffstage 1-2  (11409) larva L3 puffstage 3-6  (20171) larva L3 puffstage 7-9  (32064) white prepupae new  (37753) white prepupae 12hr  (18666) white prepupae 24hr  (16445) pupae 2d postWPP  (12399) pupae 3d postWPP  (8629) pupae 4d postWPP  (9137) adult male 01day  (7978) adult male 05day  (5732) adult male 30day  (5301) adult female 01day  (7970) adult female 05day  (16427) adult female 30day  (13816) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  14849 embryo 02-04hr    2899 embryo 04-06hr    8673 embryo 06-08hr    8979 embryo 08-10hr    6699 embryo 10-12hr    4773 embryo 12-14hr    4847 embryo 14-16hr    2443 embryo 16-18hr    2462 embryo 18-20hr    1848 embryo 20-22hr    2085 embryo 22-24hr    2515 larva L1    4217 larva L2  10394 larva L3 12hr old    5849 larva L3 puffstage 1-2  11409 larva L3 puffstage 3-6  20171 larva L3 puffstage 7-9  (32064) white prepupae new  (37753) white prepupae 12hr  18666 white prepupae 24hr  16445 pupae 2d postWPP  12399 pupae 3d postWPP    8629 pupae 4d postWPP    9137 adult male 01day    7978 adult male 05day    5732 adult male 30day    5301 adult female 01day    7970 adult female 05day  16427 adult female 30day  13816 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    14849 embryo 02-04hr    2899 embryo 04-06hr    8673 embryo 06-08hr    8979 embryo 08-10hr    6699 embryo 10-12hr    4773 embryo 12-14hr    4847 embryo 14-16hr    2443 embryo 16-18hr    2462 embryo 18-20hr    1848 embryo 20-22hr    2085 embryo 22-24hr    2515 larva L1    4217 larva L2    10394 larva L3 12hr old    5849 larva L3 puffstage 1-2    11409 larva L3 puffstage 3-6    20171 larva L3 puffstage 7-9    32064 white prepupae new    37753 white prepupae 12hr    18666 white prepupae 24hr    16445 pupae 2d postWPP    12399 pupae 3d postWPP    8629 pupae 4d postWPP    9137 adult male 01day    7978 adult male 05day    5732 adult male 30day    5301 adult female 01day    7970 adult female 05day    16427 adult female 30day    13816 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0040954    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0040954 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult central nervous system, adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0040954 expression level Tissue   Expression Level Larval Central Nervous System    995.35 Larval Midgut    1217.5 Larval Hindgut    987.8 Larval Malpighian Tubules    2255.2 Larval Fat Body    1150.3 Larval Salivary Gland    1458.8 Larval Trachea    1072.575 Larval Carcass    1541.6 Adult Head    534.5 Adult Eye    427.3 Adult Brain    366.9 Adult Thoracic-Abdominal Ganglion    416.5 Adult Crop    763.4 Adult Midgut    675.6 Adult Hindgut    581.4 Adult Malpighian Tubules    725.8 Adult Fat Body    1150.6 Adult Salivary Gland    777 Adult Heart    1302.275 Adult VirginFemale Spermatheca    851.3 Adult InseminatedFemale Spermatheca    774.1 Adult Ovary    1353.7 Adult Testis    424.3 Adult Male Accessory Gland    872.6 Adult Carcass    814.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (995.35) Larval Midgut  (1217.5) Larval Hindgut  (987.8) Larval Malpighian Tubules  (2255.2) Larval Fat Body  (1150.3) Larval Salivary Gland  (1458.8) Larval Trachea  (1072.575) Larval Carcass  (1541.6) Adult Head  534.5 Adult Eye    427.3 Adult Brain    366.9 Adult Thoracic-Abdominal Ganglion    416.5 Adult Crop  (763.4) Adult Midgut  (675.6) Adult Hindgut  (581.4) Adult Malpighian Tubules  (725.8) Adult Fat Body  (1150.6) Adult Salivary Gland  (777) Adult Heart  (1302.275) Adult VirginFemale Spermatheca  (851.3) Adult InseminatedFemale Spermatheca  (774.1) Adult Ovary  (1353.7) Adult Testis    424.3 Adult Male Accessory Gland  (872.6) Adult Carcass  (814.9) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    995.35 Larval Midgut  (1217.5) Larval Hindgut    987.8 Larval Malpighian Tubules  (2255.2) Larval Fat Body  (1150.3) Larval Salivary Gland  (1458.8) Larval Trachea  1072.575 Larval Carcass  (1541.6) Adult Head    534.5 Adult Eye    427.3 Adult Brain    366.9 Adult Thoracic-Abdominal Ganglion    416.5 Adult Crop    763.4 Adult Midgut    675.6 Adult Hindgut    581.4 Adult Malpighian Tubules    725.8 Adult Fat Body  (1150.6) Adult Salivary Gland    777 Adult Heart  (1302.275) Adult VirginFemale Spermatheca    851.3 Adult InseminatedFemale Spermatheca    774.1 Adult Ovary  (1353.7) Adult Testis    424.3 Adult Male Accessory Gland    872.6 Adult Carcass    814.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    995.35 Larval Midgut    1217.5 Larval Hindgut    987.8 Larval Malpighian Tubules    2255.2 Larval Fat Body    1150.3 Larval Salivary Gland    1458.8 Larval Trachea    1072.575 Larval Carcass    1541.6 Adult Head    534.5 Adult Eye    427.3 Adult Brain    366.9 Adult Thoracic-Abdominal Ganglion    416.5 Adult Crop    763.4 Adult Midgut    675.6 Adult Hindgut    581.4 Adult Malpighian Tubules    725.8 Adult Fat Body    1150.6 Adult Salivary Gland    777 Adult Heart    1302.275 Adult VirginFemale Spermatheca    851.3 Adult InseminatedFemale Spermatheca    774.1 Adult Ovary    1353.7 Adult Testis    424.3 Adult Male Accessory Gland    872.6 Adult Carcass    814.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0040954 expression level Tissue   Expression Level Larval Central Nervous System    995.35 Larval Midgut    1217.5 Larval Hindgut    987.8 Larval Malpighian Tubules    2255.2 Larval Fat Body    1150.3 Larval Salivary Gland    1458.8 Larval Trachea    1072.575 Larval Carcass    1541.6 Adult Head    534.5 Adult Eye    427.3 Adult Brain    366.9 Adult Thoracic-Abdominal Ganglion    416.5 Adult Crop    763.4 Adult Midgut    675.6 Adult Hindgut    581.4 Adult Malpighian Tubules    725.8 Adult Fat Body    1150.6 Adult Salivary Gland    777 Adult Heart    1302.275 Adult VirginFemale Spermatheca    851.3 Adult InseminatedFemale Spermatheca    774.1 Adult Ovary    1353.7 Adult Testis    424.3 Adult Male Accessory Gland    872.6 Adult Carcass    814.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (995.35) Larval Midgut  (1217.5) Larval Hindgut  (987.8) Larval Malpighian Tubules  (2255.2) Larval Fat Body  (1150.3) Larval Salivary Gland  (1458.8) Larval Trachea  (1072.575) Larval Carcass  (1541.6) Adult Head  534.5 Adult Eye    427.3 Adult Brain    366.9 Adult Thoracic-Abdominal Ganglion    416.5 Adult Crop  763.4 Adult Midgut  675.6 Adult Hindgut  581.4 Adult Malpighian Tubules  725.8 Adult Fat Body  (1150.6) Adult Salivary Gland  777 Adult Heart  (1302.275) Adult VirginFemale Spermatheca  (851.3) Adult InseminatedFemale Spermatheca  774.1 Adult Ovary  (1353.7) Adult Testis    424.3 Adult Male Accessory Gland  (872.6) Adult Carcass  (814.9) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    995.35 Larval Midgut  1217.5 Larval Hindgut    987.8 Larval Malpighian Tubules  (2255.2) Larval Fat Body  1150.3 Larval Salivary Gland  1458.8 Larval Trachea  1072.575 Larval Carcass  1541.6 Adult Head    534.5 Adult Eye    427.3 Adult Brain    366.9 Adult Thoracic-Abdominal Ganglion    416.5 Adult Crop    763.4 Adult Midgut    675.6 Adult Hindgut    581.4 Adult Malpighian Tubules    725.8 Adult Fat Body  1150.6 Adult Salivary Gland    777 Adult Heart  1302.275 Adult VirginFemale Spermatheca    851.3 Adult InseminatedFemale Spermatheca    774.1 Adult Ovary  1353.7 Adult Testis    424.3 Adult Male Accessory Gland    872.6 Adult Carcass    814.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    995.35 Larval Midgut    1217.5 Larval Hindgut    987.8 Larval Malpighian Tubules    2255.2 Larval Fat Body    1150.3 Larval Salivary Gland    1458.8 Larval Trachea    1072.575 Larval Carcass    1541.6 Adult Head    534.5 Adult Eye    427.3 Adult Brain    366.9 Adult Thoracic-Abdominal Ganglion    416.5 Adult Crop    763.4 Adult Midgut    675.6 Adult Hindgut    581.4 Adult Malpighian Tubules    725.8 Adult Fat Body    1150.6 Adult Salivary Gland    777 Adult Heart    1302.275 Adult VirginFemale Spermatheca    851.3 Adult InseminatedFemale Spermatheca    774.1 Adult Ovary    1353.7 Adult Testis    424.3 Adult Male Accessory Gland    872.6 Adult Carcass    814.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    534.5   NA  Eye    427.3   NA  Brain    366.9   995.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    416.5   NA  Crop    763.4   1217.5  Midgut    675.6   987.8  Hindgut    581.4   2255.2  Malpighian Tubules    725.8   1150.3  Fat Body    1150.6   1458.8  Salivary Gland    777   NA  Heart    1302.275   1072.575  Trachea    NA   NA  VirginFemale Spermatheca    851.3   NA  InseminatedFemale Spermatheca    774.1   NA  Ovary    1353.7   NA  Testis    424.3   NA  Male Accessory Gland    872.6   1541.6  Carcass    814.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_02
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040954 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13779-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL41407 CG13779GD7604 lethal | pupal stage, with Scer\GAL4pnr-MD237 CG13779GD7604 semi-lethal, with Scer\GAL4pnr-MD237 CG13779GD17354 semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG13779GD7604 Other Phenotypes Allele neuroanatomy defective | larval stage, with Scer\GAL41407 CG13779GD7604 visible, with Scer\GAL4pnr-MD237 CG13779GD7604 CG13779GD17354 Phenotype manifest in Allele ganglion mother cell | larval stage, with Scer\GAL41407 CG13779GD7604 mesothoracic tergum, with Scer\GAL4pnr-MD237 CG13779GD7604 CG13779GD17354
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG13779 Class Mutagen Stocks Known lesion CG13779c01652 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG13779 Class Mutagen Stocks Known lesion CG13779GD17354 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG13779GD7604 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG13779JF02893 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG13779KK112693 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7030 (Ryder, 2004.4.26) Df(2L)Mnn1Δ65 (Cerrato et al., 2006)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7604} NA P{GD17354} NA P{KK112693} NA P{TRiP.JF02893} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}CG13779c01652 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
peptidase activity inferred from sequence or structural similarity with UniProtKB:P60896 (assigned by UniProtKB) (Swiss-Prot Project Members, 2004.10.25)
Biological Process
CV term Evidence References
proteolysis inferred from sequence or structural similarity with UniProtKB:P60896 (assigned by UniProtKB) (Swiss-Prot Project Members, 2004.10.25)
Cellular Component
CV term Evidence References
proteasome complex inferred from sequence or structural similarity with UniProtKB:P60896 (assigned by UniProtKB) (Swiss-Prot Project Members, 2004.10.25)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG13779 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 72687 DroID - A comprehensive database of gene and protein interactions. • FBgn0040954 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 50428
Orthologs
Genome-wide drosophilid orthologs	Dana\GF20769 Dere\GG10460 Dgri\GH10099 Dmoj\GI14386 Dper\GL14107 Dpse\GA12520 Dsec\GM16322 Dvir\GJ16256 Dwil\GK24292 Dyak\GE14384
Curated drosophilid orthologs	Dpse\GA12520
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL002121-PA Aedes aegypti (mosquito) AGAP003851-PA Anopheles gambiae (mosquito) BGIBMGA011253-PA Bombyx mori (silk worm) JA10548 Caenorhabditis japonica (nematode) CPIJ010440 Culex pipens (mosquito) 327432 Daphnia pulex (daphnia) ISCW014665-PA Ixodes scapularis (deer tick) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0231992 FBgn0226253 FBgn0171238 FBgn0072566 FBgn0151712 FBgn0102769 FBgn0097775
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	28057 y1 v1; P{TRiP.JF02893}attP2
VDRC	v107661 P{KK112693}VIE-260B v31787 w1118; P{GD7604}v31787 v49153 w1118; P{GD17354}v49153 v31789 w1118; P{GD7604}v31789/CyO v49152 w1118; P{GD17354}v49152/TM3
Genomic Clones ( 2 )
	BACR13J07 BACR39J17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 42 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RH34416
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE74743 RH03658 RH03903 RH11622 RH22638 RH25926 RH30295 RH59482
Other clones	300185 bs67e05 Dmel_dig_005954_0628_2072 Dmel_dig_007956_0706_2352 Dmel_dig_014405_0669_0703 Dmel_dig_019444_0654_2491 Dmel_neb_012043_0601_2271 Dmel_neb_014304_0190_1539 Dmel_neb_014876_0323_2509 EC25726 EN17451 RH01212 RH01271 RH01349 RH01396 RP004092288 RP004101561 RP004101621 RP004118097 RP004141040 RP004203256 RP004208031 RP004219938 RP004231156 RP004235732 RP004240134 RP004249547 RP004253890 RP004254682 RP004255329 RP004259248 RP004421309 RP004440226
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0040954 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 50428
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG13779 BcDNA:RH34416 (FlyBase, 1996-)
Additional comments	Source for merge of CG13779 BcDNA:RH34416 was TrEMBL update (date:020807). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_144298 RefSeq (Proteins) • NP_652555 DDBJ / EMBL / GenBank • AAF52481 AAL48168 AY070697 BI563735 CZ467329 Entrez Gene - A searchable database of RefSeq genes. • 50428 UniProtKB/Swiss-Prot • Q9VM46
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • DSS1/SEM1 (IPR007834)
Linkouts
	BioGRID - A database of protein and genetic interactions • 72687 DroID - A comprehensive database of gene and protein interactions. • FBgn0040954 DRSC - Results from RNAi screens. • FBgn0040954 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0040954 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13779-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0040954 FlyReactome - A curated knowledgebase of Drosophila melanogaster pathways • 153693 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 50428 InParanoid A subset of ortholog calls from InParanoid. • AAEL002121-PA Aedes aegypti (mosquito) AGAP003851-PA Anopheles gambiae (mosquito) BGIBMGA011253-PA Bombyx mori (silk worm) JA10548 Caenorhabditis japonica (nematode) CPIJ010440 Culex pipens (mosquito) 327432 Daphnia pulex (daphnia) ISCW014665-PA Ixodes scapularis (deer tick) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 50428 modMine - Data generated by the modENCODE project. • FBgn0040954 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0231992 FBgn0226253 FBgn0171238 FBgn0072566 FBgn0151712 FBgn0102769 FBgn0097775
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	BcDNA:RH34416   CG13779 (Cerrato et al., 2006, Keleman et al., 2009.8.5, Perkins et al., 2009)
Name Synonym
Secondary FlyBase IDs
	FBgn0047023
References ( 16 )
Research paper	Booker et al., 2011, BMC Genomics 12: 50 False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Cerrato et al., 2006, Dev. Biol. 298(1): 59--70 Genetic interactions between Drosophila melanogaster menin and Jun/Fos. [FBrf0192703]
Supplementary material	Neumüller et al., 2011, Cell Stem Cell 8(5): Supplemental Table S1. [FBrf0214431] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]
Protein sequence record	Swiss-Prot Project Members, 2004.10.25, UniProtKB: Q9VM46 Probable 26 proteasome complex subunit sem1. [FBrf0182205]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]