The gene Peritrophin-15b is referred to in FlyBase by the symbol Dmel\Peritrophin-15b (CG31893, FBgn0040958). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: chitin binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: chitin metabolic process. One allele is reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Chitin binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected. Peak expression observed during late larval stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut. Expression at moderate levels in the following post-embryonic organs or tissues: larval hindgut. Comments on Affy2 ProbeSet: ProbeSet 1631204_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Peritrophin-15b. Gene sequence location is 2L:8394446..8395122.
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FB2013_03
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Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut. Expression at moderate levels in the following post-embryonic organs or tissues: larval hindgut.
[download data (TSV)]
Guide to FlyAtlas expression level colors
No expression (0 - 9.999)
Low expression (10 - 99.999)
Moderate expression (100 - 499.999)
High level expression (500 - 999.999)
Very high expression (>999.999)
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
1
Larval Midgut
5349.1
Larval Hindgut
417.5
Larval Malpighian Tubules
22
Larval Fat Body
7.9
Larval Salivary Gland
4
Larval Trachea
6.225
Larval Carcass
4.75
Adult Head
2.4
Adult Eye
1.125
Adult Brain
1.5
Adult Thoracic-Abdominal Ganglion
1
Adult Crop
3.5
Adult Midgut
1735.4
Adult Hindgut
34.2
Adult Malpighian Tubules
4.1
Adult Fat Body
1.4
Adult Salivary Gland
3.3
Adult Heart
1.175
Adult VirginFemale Spermatheca
2.9
Adult InseminatedFemale Spermatheca
2.3
Adult Ovary
2.4
Adult Testis
12.6
Adult Male Accessory Gland
68.2
Adult Carcass
1.7
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
1
Larval Midgut
(5349.1)
Larval Hindgut
417.5
Larval Malpighian Tubules
22
Larval Fat Body
7.9
Larval Salivary Gland
4
Larval Trachea
6.225
Larval Carcass
4.75
Adult Head
2.4
Adult Eye
1.125
Adult Brain
1.5
Adult Thoracic-Abdominal Ganglion
1
Adult Crop
3.5
Adult Midgut
(1735.4)
Adult Hindgut
34.2
Adult Malpighian Tubules
4.1
Adult Fat Body
1.4
Adult Salivary Gland
3.3
Adult Heart
1.175
Adult VirginFemale Spermatheca
2.9
Adult InseminatedFemale Spermatheca
2.3
Adult Ovary
2.4
Adult Testis
12.6
Adult Male Accessory Gland
68.2
Adult Carcass
1.7
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
1
Larval Midgut
(5349.1)
Larval Hindgut
417.5
Larval Malpighian Tubules
22
Larval Fat Body
7.9
Larval Salivary Gland
4
Larval Trachea
6.225
Larval Carcass
4.75
Adult Head
2.4
Adult Eye
1.125
Adult Brain
1.5
Adult Thoracic-Abdominal Ganglion
1
Adult Crop
3.5
Adult Midgut
(1735.4)
Adult Hindgut
34.2
Adult Malpighian Tubules
4.1
Adult Fat Body
1.4
Adult Salivary Gland
3.3
Adult Heart
1.175
Adult VirginFemale Spermatheca
2.9
Adult InseminatedFemale Spermatheca
2.3
Adult Ovary
2.4
Adult Testis
12.6
Adult Male Accessory Gland
68.2
Adult Carcass
1.7
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
1
Larval Midgut
5349.1
Larval Hindgut
417.5
Larval Malpighian Tubules
22
Larval Fat Body
7.9
Larval Salivary Gland
4
Larval Trachea
6.225
Larval Carcass
4.75
Adult Head
2.4
Adult Eye
1.125
Adult Brain
1.5
Adult Thoracic-Abdominal Ganglion
1
Adult Crop
3.5
Adult Midgut
1735.4
Adult Hindgut
34.2
Adult Malpighian Tubules
4.1
Adult Fat Body
1.4
Adult Salivary Gland
3.3
Adult Heart
1.175
Adult VirginFemale Spermatheca
2.9
Adult InseminatedFemale Spermatheca
2.3
Adult Ovary
2.4
Adult Testis
12.6
Adult Male Accessory Gland
68.2
Adult Carcass
1.7
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
1
Larval Midgut
5349.1
Larval Hindgut
417.5
Larval Malpighian Tubules
22
Larval Fat Body
7.9
Larval Salivary Gland
4
Larval Trachea
6.225
Larval Carcass
4.75
Adult Head
2.4
Adult Eye
1.125
Adult Brain
1.5
Adult Thoracic-Abdominal Ganglion
1
Adult Crop
3.5
Adult Midgut
1735.4
Adult Hindgut
34.2
Adult Malpighian Tubules
4.1
Adult Fat Body
1.4
Adult Salivary Gland
3.3
Adult Heart
1.175
Adult VirginFemale Spermatheca
2.9
Adult InseminatedFemale Spermatheca
2.3
Adult Ovary
2.4
Adult Testis
12.6
Adult Male Accessory Gland
68.2
Adult Carcass
1.7
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
1
Larval Midgut
(5349.1)
Larval Hindgut
417.5
Larval Malpighian Tubules
22
Larval Fat Body
7.9
Larval Salivary Gland
4
Larval Trachea
6.225
Larval Carcass
4.75
Adult Head
2.4
Adult Eye
1.125
Adult Brain
1.5
Adult Thoracic-Abdominal Ganglion
1
Adult Crop
3.5
Adult Midgut
(1735.4)
Adult Hindgut
34.2
Adult Malpighian Tubules
4.1
Adult Fat Body
1.4
Adult Salivary Gland
3.3
Adult Heart
1.175
Adult VirginFemale Spermatheca
2.9
Adult InseminatedFemale Spermatheca
2.3
Adult Ovary
2.4
Adult Testis
12.6
Adult Male Accessory Gland
68.2
Adult Carcass
1.7
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
1
Larval Midgut
(5349.1)
Larval Hindgut
417.5
Larval Malpighian Tubules
22
Larval Fat Body
7.9
Larval Salivary Gland
4
Larval Trachea
6.225
Larval Carcass
4.75
Adult Head
2.4
Adult Eye
1.125
Adult Brain
1.5
Adult Thoracic-Abdominal Ganglion
1
Adult Crop
3.5
Adult Midgut
(1735.4)
Adult Hindgut
34.2
Adult Malpighian Tubules
4.1
Adult Fat Body
1.4
Adult Salivary Gland
3.3
Adult Heart
1.175
Adult VirginFemale Spermatheca
2.9
Adult InseminatedFemale Spermatheca
2.3
Adult Ovary
2.4
Adult Testis
12.6
Adult Male Accessory Gland
68.2
Adult Carcass
1.7
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
1
Larval Midgut
5349.1
Larval Hindgut
417.5
Larval Malpighian Tubules
22
Larval Fat Body
7.9
Larval Salivary Gland
4
Larval Trachea
6.225
Larval Carcass
4.75
Adult Head
2.4
Adult Eye
1.125
Adult Brain
1.5
Adult Thoracic-Abdominal Ganglion
1
Adult Crop
3.5
Adult Midgut
1735.4
Adult Hindgut
34.2
Adult Malpighian Tubules
4.1
Adult Fat Body
1.4
Adult Salivary Gland
3.3
Adult Heart
1.175
Adult VirginFemale Spermatheca
2.9
Adult InseminatedFemale Spermatheca
2.3
Adult Ovary
2.4
Adult Testis
12.6
Adult Male Accessory Gland
68.2
Adult Carcass
1.7
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected. Peak expression observed during late larval stages.
[download data (TSV)]
Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 5 )
Please Note
This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see GBrowse for alignment of the cDNAs and ESTs
to the gene model.
Chakrabarti et al., 2012, Cell Host Microbe 12(1): 60--70
Infection-induced host translational blockage inhibits immune responses and epithelial renewal in the Drosophila gut. [FBrf0218984]
Levine et al., 2011, Mol. Biol. Evol. 28(1): 249--256
Whole-Genome Expression Plasticity across Tropical and Temperate Drosophila melanogaster Populations from Eastern Australia. [FBrf0212629]
Fernández-Ayala et al., 2010, PLoS ONE 5(1): e8549
Gene expression in a Drosophila model of mitochondrial disease. [FBrf0209705]
Wagstaff and Begun, 2005, Mol. Biol. Evol. 22(4): 818--832
Comparative Genomics of Accessory Gland Protein Genes in Drosophila melanogaster and D. pseudoobscura. [FBrf0184145]
Wijffels et al., 2001, J. Biol. Chem. 276(18): 15527--15536
A novel family of chitin-binding proteins from insect type 2 peritrophic matrix. cDNA sequences, chitin binding activity, and cellular localization. [FBrf0135836]