conserved proteins acting downstream of PKB and upstream of TSC to regulate growth - they are induced under hypoxic conditions, thus establishing a potential cross-talk between growth and oxygen sensing - required for head involution
Gene model reviewed during 5.50
Gene model reviewed during 5.51
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\scyl using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\scyl in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of scyl anon-WO0118547.215 was sequence comparison ( date:051113 ).
Embryos injected with dsRNA made from templates generated with primers directed against this gene show no observable phenotype. However, embryos injected with dsRNA against both this gene and chrb are embryonic lethal and show defects in head involution.
Area matching Drosophila ESTs AA950084 and AA978669.