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Gene Dmel\scyl

General Information
Symbol	Dmel\scyl	Species	D. melanogaster
Name	scylla	Annotation symbol	CG7590
Feature type	protein_coding_gene	FlyBase ID	FBgn0041094
Created / Updated	2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	68B4-68C1	Sequence location	3L:11,245,409..11,248,621 [+]
Map ( GBrowse )	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene scylla is referred to in FlyBase by the symbol scyl (CG7590, FBgn0041094). It has the cytological map location 68B4-68C1. Its sequence location is 3L:11245409..11248621. Its molecular function is unknown. It is involved in the biological processes: negative regulation of growth; head involution; cell death; negative regulation of signal transduction. 13 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.
External Summaries
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 68B4-68C1   Limits computationally determined from genome sequence between P{PZ}l(3)0123901239&P{lacW}l(3)01239j9B4 and P{PZ}CycA02461&P{PZ}CycA03946
Experimentally Determined Cytological Location
Cytogenetic map Notes References 68C-68C   (Chauvet, 2000.1.5)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology) References Gene Order (overall orientation not stated) References
Gene Model & Products
Please see the GBrowse view of Dmel\scyl for information on other features
Comments on Gene Model
	DGC clone LD22812 appears problematic: unspliced intron
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) scyl-RA FBtr0076168  NM_140199   2471   280 scyl-RB FBtr0076169  NM_206321   3213   241
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kD) Length (aa) Theoretical pI RefSeq ID GenBank protein scyl-PA   FBpp0075899   30.8   280   9.57     NP_648456   AAF50074 scyl-PB   FBpp0089347   26.3   241   9.52     NP_996043   AAS65038
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts	PANTHER - Protein classification by function, families, and pathways • FBgn0041094
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • RTP801, C-terminal (IPR012918)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202362   AA246952   AA263528   AA264627   AA264750   AA392103   AA392303   AA392403   AA438360   AA439566   AA440512   AA441270   AA694845   AA697781   AA816267   AA940697   AA941222   AA950084   AA950099   AA950700   AA978669   AE003545 AAF50074   AE003545 AAS65038   AF221110 AAF59841   AI108753   AI238649   AI256907   AI257549   AI297152   AI388354   AI389068   AI945964   AX094091   AY075382 AAL68220   BG637733   BI166141   BI166766   BI166848   BI173305   BI213450   BI228789   BI229896   BI234047   BI235817   BI236487   BI236714   BI237922   BI241989   BI242975   BI243800   BI353553   BI353555   BI353561   BI366415   BI366820   BI373535   BI374006   BI484295   BI486821   BI568139   BI577625   BI579163   BI579876   BI610057   BI614170   BI638963   BI640169   BP543355   BP543356   BP546735   BP558314   BQ103144   BQ103517   BT015975 AAV36860   CK131605   CO185292   CO188673   CO188968   CO196248   CO262915   CO263694   CO266549   CO267675   CO274196   CO279842   CO283725   CO285767   CO285976   CO287235   CO287584   CO288014   CO289006   CO289486   CO289635   CO290127   CO291089   CO292277   CO292794   CO292824   CO294933   CO295507   CO295569   CO298430   CO301065   CO301279   CO302217   CO309401   CO309465   CO313875   CO314181   CO314931   CO315695   CO323185   CO330563   CO331565   CO331728   CO332420   CO333871   CO339896   CO340970   CO341143   CO341779   CZ470066   CZ470068   CZ485550   CZ485551   EC058795   EC058807   EC060585   EC062498   EC065384   EC069939   EC070233   EC070665   EC071179   EC075885   EC076894   EC080638   EC080740   EC081430   EC084510   EC087030   EC090558   EC195738   EC195933   EC196173   EC196756   EC200321   EC204747   EC204872   EC208032   EC212480   EC212488   EC215582   EC216502   EC216772   EC220454   EC220456   EC223657   EC224461   EC225705   EC226701   EC228803   EC229727   EC232887   EC233263   EC233359   EC234703   EC235982   EC236415   EC238396   EC241445   EC244183   EC246993   EC247131   EC247839   EC247905   EC249519   EC250820   EC253423   EC258674   EC260395   EC265047
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VTH4
Maps to
Does NOT map to
Identified with	bs18h04 LD08235 (Oliver, 2001.8.16) LD22812 RE71335 (BDGP Project Members, 2000-)
Mapped Features & Mutations
Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
FlyBase-Curated Data
Transcript and Protein data	Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
Summary of Transcript Expression
Stage Tissue/Position Reference
Marker for
Subcellular Localization
CV Term
Summary of Polypeptide Expression
Stage Tissue/Position Reference
Marker for
Subcellular Localization
CV Term
Microarray Data
	Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002) AA940697
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0041094 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • FBgn0041094 GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies • FBgn0041094
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable scylEY03729 scylunspecified Other Phenotypes Allele small body, with Scer\GAL4Act5C.PF scylEP22.1 reduced cell size | somatic clone, with Scer\GAL4GMR.PB scylEP22.1 reduced cell size, with Scer\GAL4Act5C.PF scylEP22.1 long lived, with Scer\GAL4da.G32 scylEP22.1 Sterility Allele fertile scylunspecified Phenotype manifest in Allele
Classical Alleles ( 9 )
For All Classical Alleles Show
Allele of scyl Class Mutagen Stocks Known lesion scyl113 Δ2-3 0 Yes scyl31 Δ2-3 0 Yes scylEP22.1 0 Yes scylEP9.85 0 Yes scylEY03729 0 Yes scylZCL0611 P-element activity 1 -- scylc05525 piggyBac transposase 0 -- scylf02993 piggyBac transposase 1 -- scylunspecified 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of scyl Class Mutagen Stocks Known lesion scylGD16504 in vitro construct | RNAi in vitro construct | regulatory fusion 0 Yes scylGD9925 in vitro construct | RNAi