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Gene Dmel\ida

General Information
Symbol	Dmel\ida	Species	D. melanogaster
Name	imaginal discs arrested	Annotation symbol	CG10850
Feature type	protein_coding_gene	FlyBase ID	FBgn0041147
Gene Model Status	Current	Stock availability	8 publicly available
Also Known As	APC5, l(3)63Fb
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	63F6-63F6	Sequence location	3L:3,905,344..3,907,908 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene imaginal discs arrested is referred to in FlyBase by the symbol Dmel\ida (CG10850, FBgn0041147). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding. There is experimental evidence that it is involved in the biological process: mitotic cell cycle; imaginal disc development; neurogenesis. 11 alleles are reported. The phenotypes of these alleles are annotated with: organ system; imaginal precursor; multicellular structure; cell cycle; cellular component organization or biogenesis; cell cycle process; eo support cell; salivary gland imaginal ring; organ system subdivision; embryonic/larval imaginal precursor. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Tetratricopeptide-like helical. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1641316_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of ida. Gene sequence location is 3L:3905344..3907908.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	References Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593
FB2012_01	Sequence features HFA08163 BKN22332 Alleles ida[PL17]
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 63F6-63F6   Limits computationally determined from genome sequence between P{PZ}Sc205634 and P{PZ}l(3)rG166rG166
Experimentally Determined Cytological Location
Cytogenetic map Notes References 63F-63F     (Bentley, 2000.10.9)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\ida for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) ida-RA FBtr0073160  NM_139580   2503   777 ida-RB FBtr0073161  NM_206273   2493   705
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein ida-PA   FBpp0073018   88.8   777   9.17     NP_647837   AAF47808 ida-PB   FBpp0089265   80.6   705   9.08     NP_995995   AAS64965
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Tetratricopeptide-like helical (IPR011990)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF47808   AE014296 AAS64965   AF312026 AAL82192   AI294935   AY119221 AAM51081   BE976226   BF490846   BF499855   BF501503   BI351616   BI355755   BI635373   BT044355   CO267358   CO317062   CO324063   CO325336   EC086363   EC089498   EC222037   EC223757   ES694222
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7KV60 Q8MRX0 Q8TA45 Q9VZL2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0041147    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0041147 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0041147 expression level Developmental Stage   Expression Level embryo 00-02hr    1198 embryo 02-04hr    459 embryo 04-06hr    866 embryo 06-08hr    534 embryo 08-10hr    366 embryo 10-12hr    202 embryo 12-14hr    151 embryo 14-16hr    71 embryo 16-18hr    58 embryo 18-20hr    33 embryo 20-22hr    30 embryo 22-24hr    47 larva L1    156 larva L2    203 larva L3 12hr old    171 larva L3 puffstage 1-2    242 larva L3 puffstage 3-6    303 larva L3 puffstage 7-9    350 white prepupae new    349 white prepupae 12hr    336 white prepupae 24hr    467 pupae 2d postWPP    288 pupae 3d postWPP    178 pupae 4d postWPP    148 adult male 01day    250 adult male 05day    309 adult male 30day    298 adult female 01day    435 adult female 05day    933 adult female 30day    943 Expression Level Scale  None   Extremely low   Very low   Low   Moderate  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1198) embryo 02-04hr  (459) embryo 04-06hr  (866) embryo 06-08hr  (534) embryo 08-10hr  (366) embryo 10-12hr  (202) embryo 12-14hr  (151) embryo 14-16hr    71 embryo 16-18hr    58 embryo 18-20hr    33 embryo 20-22hr    30 embryo 22-24hr    47 larva L1  (156) larva L2  (203) larva L3 12hr old  (171) larva L3 puffstage 1-2  (242) larva L3 puffstage 3-6  (303) larva L3 puffstage 7-9  (350) white prepupae new  (349) white prepupae 12hr  (336) white prepupae 24hr  (467) pupae 2d postWPP  (288) pupae 3d postWPP  (178) pupae 4d postWPP  (148) adult male 01day  (250) adult male 05day  (309) adult male 30day  (298) adult female 01day  (435) adult female 05day  (933) adult female 30day  (943) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1198 embryo 02-04hr    459 embryo 04-06hr    866 embryo 06-08hr    534 embryo 08-10hr    366 embryo 10-12hr    202 embryo 12-14hr    151 embryo 14-16hr    71 embryo 16-18hr    58 embryo 18-20hr    33 embryo 20-22hr    30 embryo 22-24hr    47 larva L1    156 larva L2    203 larva L3 12hr old    171 larva L3 puffstage 1-2    242 larva L3 puffstage 3-6    303 larva L3 puffstage 7-9    350 white prepupae new    349 white prepupae 12hr    336 white prepupae 24hr    467 pupae 2d postWPP    288 pupae 3d postWPP    178 pupae 4d postWPP    148 adult male 01day    250 adult male 05day    309 adult male 30day    298 adult female 01day    435 adult female 05day    933 adult female 30day    943 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1198 embryo 02-04hr    459 embryo 04-06hr    866 embryo 06-08hr    534 embryo 08-10hr    366 embryo 10-12hr    202 embryo 12-14hr    151 embryo 14-16hr    71 embryo 16-18hr    58 embryo 18-20hr    33 embryo 20-22hr    30 embryo 22-24hr    47 larva L1    156 larva L2    203 larva L3 12hr old    171 larva L3 puffstage 1-2    242 larva L3 puffstage 3-6    303 larva L3 puffstage 7-9    350 white prepupae new    349 white prepupae 12hr    336 white prepupae 24hr    467 pupae 2d postWPP    288 pupae 3d postWPP    178 pupae 4d postWPP    148 adult male 01day    250 adult male 05day    309 adult male 30day    298 adult female 01day    435 adult female 05day    933 adult female 30day    943 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1198 embryo 02-04hr    459 embryo 04-06hr    866 embryo 06-08hr    534 embryo 08-10hr    366 embryo 10-12hr    202 embryo 12-14hr    151 embryo 14-16hr    71 embryo 16-18hr    58 embryo 18-20hr    33 embryo 20-22hr    30 embryo 22-24hr    47 larva L1    156 larva L2    203 larva L3 12hr old    171 larva L3 puffstage 1-2    242 larva L3 puffstage 3-6    303 larva L3 puffstage 7-9    350 white prepupae new    349 white prepupae 12hr    336 white prepupae 24hr    467 pupae 2d postWPP    288 pupae 3d postWPP    178 pupae 4d postWPP    148 adult male 01day    250 adult male 05day    309 adult male 30day    298 adult female 01day    435 adult female 05day    933 adult female 30day    943 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0041147 expression level Developmental Stage   Expression Level embryo 00-02hr    1198 embryo 02-04hr    459 embryo 04-06hr    866 embryo 06-08hr    534 embryo 08-10hr    366 embryo 10-12hr    202 embryo 12-14hr    151 embryo 14-16hr    71 embryo 16-18hr    58 embryo 18-20hr    33 embryo 20-22hr    30 embryo 22-24hr    47 larva L1    156 larva L2    203 larva L3 12hr old    171 larva L3 puffstage 1-2    242 larva L3 puffstage 3-6    303 larva L3 puffstage 7-9    350 white prepupae new    349 white prepupae 12hr    336 white prepupae 24hr    467 pupae 2d postWPP    288 pupae 3d postWPP    178 pupae 4d postWPP    148 adult male 01day    250 adult male 05day    309 adult male 30day    298 adult female 01day    435 adult female 05day    933 adult female 30day    943 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1198) embryo 02-04hr  (459) embryo 04-06hr  (866) embryo 06-08hr  (534) embryo 08-10hr  (366) embryo 10-12hr  (202) embryo 12-14hr  (151) embryo 14-16hr    71 embryo 16-18hr    58 embryo 18-20hr    33 embryo 20-22hr    30 embryo 22-24hr    47 larva L1  (156) larva L2  (203) larva L3 12hr old  (171) larva L3 puffstage 1-2  (242) larva L3 puffstage 3-6  (303) larva L3 puffstage 7-9  (350) white prepupae new  (349) white prepupae 12hr  (336) white prepupae 24hr  (467) pupae 2d postWPP  (288) pupae 3d postWPP  (178) pupae 4d postWPP  (148) adult male 01day  (250) adult male 05day  (309) adult male 30day  (298) adult female 01day  (435) adult female 05day  (933) adult female 30day  (943) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1198 embryo 02-04hr    459 embryo 04-06hr    866 embryo 06-08hr    534 embryo 08-10hr    366 embryo 10-12hr    202 embryo 12-14hr    151 embryo 14-16hr    71 embryo 16-18hr    58 embryo 18-20hr    33 embryo 20-22hr    30 embryo 22-24hr    47 larva L1    156 larva L2    203 larva L3 12hr old    171 larva L3 puffstage 1-2    242 larva L3 puffstage 3-6    303 larva L3 puffstage 7-9    350 white prepupae new    349 white prepupae 12hr    336 white prepupae 24hr    467 pupae 2d postWPP    288 pupae 3d postWPP    178 pupae 4d postWPP    148 adult male 01day    250 adult male 05day    309 adult male 30day    298 adult female 01day    435 adult female 05day    933 adult female 30day    943 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1198 embryo 02-04hr    459 embryo 04-06hr    866 embryo 06-08hr    534 embryo 08-10hr    366 embryo 10-12hr    202 embryo 12-14hr    151 embryo 14-16hr    71 embryo 16-18hr    58 embryo 18-20hr    33 embryo 20-22hr    30 embryo 22-24hr    47 larva L1    156 larva L2    203 larva L3 12hr old    171 larva L3 puffstage 1-2    242 larva L3 puffstage 3-6    303 larva L3 puffstage 7-9    350 white prepupae new    349 white prepupae 12hr    336 white prepupae 24hr    467 pupae 2d postWPP    288 pupae 3d postWPP    178 pupae 4d postWPP    148 adult male 01day    250 adult male 05day    309 adult male 30day    298 adult female 01day    435 adult female 05day    933 adult female 30day    943 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1198 embryo 02-04hr    459 embryo 04-06hr    866 embryo 06-08hr    534 embryo 08-10hr    366 embryo 10-12hr    202 embryo 12-14hr    151 embryo 14-16hr    71 embryo 16-18hr    58 embryo 18-20hr    33 embryo 20-22hr    30 embryo 22-24hr    47 larva L1    156 larva L2    203 larva L3 12hr old    171 larva L3 puffstage 1-2    242 larva L3 puffstage 3-6    303 larva L3 puffstage 7-9    350 white prepupae new    349 white prepupae 12hr    336 white prepupae 24hr    467 pupae 2d postWPP    288 pupae 3d postWPP    178 pupae 4d postWPP    148 adult male 01day    250 adult male 05day    309 adult male 30day    298 adult female 01day    435 adult female 05day    933 adult female 30day    943 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0041147    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0041147 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0041147 expression level Tissue   Expression Level Larval Central Nervous System    93.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    25.5 Larval Fat Body no informative data Larval Salivary Gland    45.7 Larval Trachea    38.175 Larval Carcass    27.2 Adult Head no informative data Adult Eye no informative data Adult Brain    26.4 Adult Thoracic-Abdominal Ganglion    34.8 Adult Crop    58.9 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    28.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.375 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    121.5 Adult Testis    63.8 Adult Male Accessory Gland no informative data Adult Carcass    8.5 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    93.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    25.5 Larval Fat Body no informative data Larval Salivary Gland    45.7 Larval Trachea    38.175 Larval Carcass    27.2 Adult Head no informative data Adult Eye no informative data Adult Brain    26.4 Adult Thoracic-Abdominal Ganglion    34.8 Adult Crop    58.9 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    28.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.375 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    121.5 Adult Testis    63.8 Adult Male Accessory Gland no informative data Adult Carcass    8.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    93.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    25.5 Larval Fat Body no informative data Larval Salivary Gland    45.7 Larval Trachea    38.175 Larval Carcass    27.2 Adult Head no informative data Adult Eye no informative data Adult Brain    26.4 Adult Thoracic-Abdominal Ganglion    34.8 Adult Crop    58.9 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    28.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.375 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    121.5 Adult Testis    63.8 Adult Male Accessory Gland no informative data Adult Carcass    8.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    93.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    25.5 Larval Fat Body no informative data Larval Salivary Gland    45.7 Larval Trachea    38.175 Larval Carcass    27.2 Adult Head no informative data Adult Eye no informative data Adult Brain    26.4 Adult Thoracic-Abdominal Ganglion    34.8 Adult Crop    58.9 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    28.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.375 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    121.5 Adult Testis    63.8 Adult Male Accessory Gland no informative data Adult Carcass    8.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0041147 expression level Tissue   Expression Level Larval Central Nervous System    93.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    25.5 Larval Fat Body no informative data Larval Salivary Gland    45.7 Larval Trachea    38.175 Larval Carcass    27.2 Adult Head no informative data Adult Eye no informative data Adult Brain    26.4 Adult Thoracic-Abdominal Ganglion    34.8 Adult Crop    58.9 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    28.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.375 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    121.5 Adult Testis    63.8 Adult Male Accessory Gland no informative data Adult Carcass    8.5 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    93.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    25.5 Larval Fat Body no informative data Larval Salivary Gland    45.7 Larval Trachea    38.175 Larval Carcass    27.2 Adult Head no informative data Adult Eye no informative data Adult Brain    26.4 Adult Thoracic-Abdominal Ganglion    34.8 Adult Crop    58.9 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    28.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.375 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    121.5 Adult Testis    63.8 Adult Male Accessory Gland no informative data Adult Carcass    8.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    93.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    25.5 Larval Fat Body no informative data Larval Salivary Gland    45.7 Larval Trachea    38.175 Larval Carcass    27.2 Adult Head no informative data Adult Eye no informative data Adult Brain    26.4 Adult Thoracic-Abdominal Ganglion    34.8 Adult Crop    58.9 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    28.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.375 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    121.5 Adult Testis    63.8 Adult Male Accessory Gland no informative data Adult Carcass    8.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    93.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    25.5 Larval Fat Body no informative data Larval Salivary Gland    45.7 Larval Trachea    38.175 Larval Carcass    27.2 Adult Head no informative data Adult Eye no informative data Adult Brain    26.4 Adult Thoracic-Abdominal Ganglion    34.8 Adult Crop    58.9 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    28.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.375 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    121.5 Adult Testis    63.8 Adult Male Accessory Gland no informative data Adult Carcass    8.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules     Larval Fat Body no informative data Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head no informative data Adult Eye no informative data Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules     Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    no informative data   NA  Brain    26.4   93.15  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    34.8   NA  Crop    58.9   no informative data  Midgut    no informative data   no informative data  Hindgut    no informative data   25.5  Malpighian Tubules    28.7   no informative data  Fat Body    no informative data   45.7  Salivary Gland    no informative data   NA  Heart    18.375   38.175  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    121.5   NA  Testis    63.8   NA  Male Accessory Gland    no informative data   27.2  Carcass    8.5 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0041147 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10850-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL41407 idaGD5998 lethal (with Df(3L)GN19) idaB4 idaD14 lethal | prepupal stage (with Df(3L)GN19) idaB4 idaD14 idaΔ107 lethal | prepupal stage | recessive idaB4 idaD14 idaΔ107 lethal | P-stage | recessive idaPL17 lethal | pupal stage | recessive idaunspecified lethal | recessive idaB4 idaD14 viable, with Scer\GAL4pnr-MD237 idaGD5998 Sterility Allele female sterile | germline clone | recessive idaB4 idaD14 idaΔ107 Other Phenotypes Allele mitotic cell cycle defective idaD14 idaΔ107 mitotic cell cycle defective | third instar larval stage idaPL17 neuroanatomy defective | larval stage, with Scer\GAL41407 idaGD5998 neuroanatomy defective | third instar larval stage idaPL17 visible, with Scer\GAL4pnr-MD237 idaGD5998 Phenotype manifest in Allele air bubble idaΔ107 embryonic/larval brain | third instar larval stage idaPL17 embryonic/larval neuroblast | larval stage, with Scer\GAL41407 idaGD5998 embryonic/larval optic lobe | third instar larval stage idaPL17 foregut imaginal ring idaΔ107 ganglion mother cell | larval stage, with Scer\GAL41407 idaGD5998 hindgut imaginal ring idaΔ107 imaginal disc idaΔ107 idaB4 mesothoracic tergum, with Scer\GAL4pnr-MD237 idaGD5998 midgut imaginal island idaΔ107 mitotic anaphase idaΔ107 mitotic cell cycle idaΔ107 idaD14 idadsRNA.cBa mitotic prometaphase idaΔ107 idaD14 salivary gland imaginal ring idaΔ107 testis idaunspecified trichogen cell, with Scer\GAL4pnr-MD237 idaGD5998
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of ida Class Mutagen Stocks Known lesion idaB4 amorphic allele - genetic evidence ethyl methanesulfonate 2 Yes idaD14 amorphic allele - genetic evidence ethyl methanesulfonate 2 Yes idaPL17 ethyl methanesulfonate 0 -- idaunspecified 0 -- idaΔ107 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of ida Class Mutagen Stocks Known lesion idaGD5998 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes idaHMS01024 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes idaKK102266 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes idadsRNA.cBa in vitro construct - RNAi 0 Yes idat63F.dc in vitro construct - genomic fragment 0 Yes idat63F.K1 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)449 (Vaskova et al., 2000) Df(3L)Exel6098 (Ryder, 2004.4.26) Df(3L)GN19 (Vaskova et al., 2000, Bentley et al., 2002, Harrison et al., 1995) Df(3L)GN34 (Harrison et al., 1995, Slack et al., 2006) Df(3L)HR119 (Slack et al., 2006) Df(3L)HR298 (Harrison et al., 1995)
Not disrupted in	Df(3L)C175 (Harrison et al., 1995) Df(3L)TE1 (Harrison et al., 1995)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5998} NA P{KK102266} NA P{TRiP.HMS01024} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
imaginal disc development inferred from mutant phenotype (Bentley et al., 2002) mitotic cell cycle inferred from mutant phenotype (Bentley et al., 2002) neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
binding inferred from electronic annotation with InterPro:IPR011990 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
mitotic anaphase non-traceable author statement (Bentley, 2000.10.9) regulation of cell cycle traceable author statement (Lee and Orr-Weaver, 2003) regulation of proteolysis traceable author statement (Lee and Orr-Weaver, 2003)
Cellular Component
CV term Evidence References
anaphase-promoting complex non-traceable author statement (Bentley, 2000.10.9) traceable author statement (Lee and Orr-Weaver, 2003)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions ida allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0041147 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 45574
Orthologs
Genome-wide drosophilid orthologs	Dana\GF24233 Dere\GG15170 Dgri\GH15768 Dmoj\GI12547 Dper\GL16057 Dpse\GA28471 Dsec\GM14598 Dvir\GJ16065 Dwil\GK17758 Dyak\ida
Curated drosophilid orthologs	Dpse\GA10598   Dyak\ida
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL002752-PA Aedes aegypti (mosquito) AGAP005578-PA Anopheles gambiae (mosquito) XP_393771.3 Apis mellifera (honey bee) XP_001950405.1 Acyrthosiphon pisum (pea aphid) 100007 Branchiostoma floridae (lancelet) BGIBMGA006210-PA Bombyx mori (silk worm) ENSBTAP00000004025 Bos taurus (bovine) ENSCAFP00000012213 Canis familiaris (dog) CPIJ015211 Culex pipens (mosquito) CPIJ019535 Culex pipens (mosquito) ENSCPOP00000010389 Cavia porcellus (guinea pig) 226543 Capitella spl (polychaete worm) DDB0234269 Dictyostelium discoideum (amoeba) DEHA2C08668g Debaryomyces Hansenii (yeast) 262056 Daphnia pulex (daphnia) ENSDARP00000019505 Danio rerio (zebra fish) ENSECAP00000021633 Equus caballus (horse) ENSGACP00000016570 Gymnopilus aculeatus (mushroom) ENSGALP00000006629 Gallus gallus (chicken) 193432 Hypsipyla robusta (cedar shoot borer) ENSP00000261819 Homo sapiens (human) ISCW005436-PA Ixodes scapularis (deer tick) 238189 Lottia gigantea (owl limpet) ENSMODP00000015069 Monodelphis domestica (gray opossum) ENSMUSP00000083393 Mus musculus (house mouse) 246586 Nematostella vectensis (starlet anemone) XP_001603245.1 Nasonia vitripennis (wasp) ENSOANP00000001245 Ornithorynchus anatinus (platypus) ENSORLP00000018224 Oryzias latipes (japanese killifish) LOC_Os12g43120.1 Oryza sativa (asian rice) PHUM010817-PA Pediculus humanus (human body louse) 10927 Physcomitrella patens (moss) ENSPPYP00000005751 Pongo pygmaeus (orangutan) ENSPTRP00000009433 Pan troglodytes (chimpanzee) ENSRNOP00000001794 Rattus norvegicus (norway rat) 5052917 Sorghum bicolor (sorghum) XP_001196812.1 Strongylocentrotus purpuratus (purple sea urchin) XP_967402.2 Tribolium castaneum (red flour beetle) ENSTNIP00000014427 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000041803 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000045303 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13274 LH17856 ISCW005436 FBgn0067964 FBgn0219757 FBgn0203250 FBgn0202722 FBgn0185488 FBgn0185487 FBgn0169519 FBgn0249831 JGI_V11_262056 FBgn0153661 FBgn0135304 FBgn0123239 FBgn0107423 FBgn0101227 CPIJ015211 CPIJ019535 BGIBMGA006210 ACYPI005294 GB18016 AGAP005578 AAEL002752 PB24041 PHUM541170 GLEAN_01292
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	34552 y1 sc* v1; P{TRiP.HMS01024}attP2 5167 bw1; idaB4 st1/TM6B, Tb+ 5168 bw1; idaD14 st1/TM6B, Tb1
Kyoto	108083 bw1; idaB4 st1/TM6B, Tb+ 108084 bw1; idaD14 st1/TM6B, Tb1
VDRC	v108634 P{KK102266}VIE-260B v18845 w1118; P{GD5998}v18845 v18847 w1118; P{GD5998}v18847
Genomic Clones ( 1 )
	BACR28E17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 17 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD16707
Other clones	FI07771
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT14625 AT16861 AT27456 GM15413 GM32206 LP08426
Other clones	37598 65545 67325 163003 bs48c12 EK149545 EK192441 EK196144 EK267012
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0041147 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 45574
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: ida APC5 (Lee, 2001.8.28)
Source for database merge of	Source for merge of: ida CG10850 (FlyBase, 1996-)
Additional comments	Source for merge of ida CG10850 was sequence comparison (date:020313). (FlyBase, 1996-)
Other Comments
	Homozygous mutants have mitotic defects, die during prepupal development, lack all mature imaginal disc structures and have abnormally small optic lobes. (Bentley et al., 2002) ida is required for viability during metamorphosis and for proliferation of the adult fated imaginal disc cells. (Bentley et al., 2000) Mutant animals lack all differentiated imaginal disc structures and have smaller than normal optic lobes. The mutation does not block mitosis, but prevents chromosomes from condensing properly and reaching the metaphase plate. (Bentley et al., 2000) ida is required for imaginal disc development. (Vaskova et al., 2000) Discussed during genetic analysis of the Ras64B-Rop region. (Harrison et al., 1995)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139580 NM_206273 RefSeq (Proteins) • NP_647837 NP_995995 DDBJ / EMBL / GenBank • AAF47808 AAL82192 AAM51081 AAS64965 AF312026 AY119221 BI635373 Entrez Gene - A searchable database of RefSeq genes. • 45574 UniProtKB/TrEMBL • Q7KV60 Q8MRX0 Q8TA45 Q9VZL2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Tetratricopeptide-like helical (IPR011990)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0041147 DRSC - Results from RNAi screens. • FBgn0041147 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0041147 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10850-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0041147 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 45574 InParanoid A subset of ortholog calls from InParanoid. • AAEL002752-PA Aedes aegypti (mosquito) AGAP005578-PA Anopheles gambiae (mosquito) XP_393771.3 Apis mellifera (honey bee) XP_001950405.1 Acyrthosiphon pisum (pea aphid) 100007 Branchiostoma floridae (lancelet) BGIBMGA006210-PA Bombyx mori (silk worm) ENSBTAP00000004025 Bos taurus (bovine) ENSCAFP00000012213 Canis familiaris (dog) CPIJ015211 Culex pipens (mosquito) CPIJ019535 Culex pipens (mosquito) ENSCPOP00000010389 Cavia porcellus (guinea pig) 226543 Capitella spl (polychaete worm) DDB0234269 Dictyostelium discoideum (amoeba) DEHA2C08668g Debaryomyces Hansenii (yeast) 262056 Daphnia pulex (daphnia) ENSDARP00000019505 Danio rerio (zebra fish) ENSECAP00000021633 Equus caballus (horse) ENSGACP00000016570 Gymnopilus aculeatus (mushroom) ENSGALP00000006629 Gallus gallus (chicken) 193432 Hypsipyla robusta (cedar shoot borer) ENSP00000261819 Homo sapiens (human) ISCW005436-PA Ixodes scapularis (deer tick) 238189 Lottia gigantea (owl limpet) ENSMODP00000015069 Monodelphis domestica (gray opossum) ENSMUSP00000083393 Mus musculus (house mouse) 246586 Nematostella vectensis (starlet anemone) XP_001603245.1 Nasonia vitripennis (wasp) ENSOANP00000001245 Ornithorynchus anatinus (platypus) ENSORLP00000018224 Oryzias latipes (japanese killifish) LOC_Os12g43120.1 Oryza sativa (asian rice) PHUM010817-PA Pediculus humanus (human body louse) 10927 Physcomitrella patens (moss) ENSPPYP00000005751 Pongo pygmaeus (orangutan) ENSPTRP00000009433 Pan troglodytes (chimpanzee) ENSRNOP00000001794 Rattus norvegicus (norway rat) 5052917 Sorghum bicolor (sorghum) XP_001196812.1 Strongylocentrotus purpuratus (purple sea urchin) XP_967402.2 Tribolium castaneum (red flour beetle) ENSTNIP00000014427 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000041803 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000045303 Xenopus tropicalis (frog) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /genebrief/imagdiscarrest.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 45574 modMine - Data generated by the modENCODE project. • FBgn0041147 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13274 LH17856 ISCW005436 FBgn0067964 FBgn0219757 FBgn0203250 FBgn0202722 FBgn0185488 FBgn0185487 FBgn0169519 FBgn0249831 JGI_V11_262056 FBgn0153661 FBgn0135304 FBgn0123239 FBgn0107423 FBgn0101227 CPIJ015211 CPIJ019535 BGIBMGA006210 ACYPI005294 GB18016 AGAP005578 AAEL002752 PB24041 PHUM541170 GLEAN_01292
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	APC5 (Lee, 2001.8.28, Lee et al., 2001, Somma et al., 2008, Buttitta et al., 2010, Silies and Klämbt, 2010) Apc5 (Tanaka-Matakatsu et al., 2007) CG10850 (Harper et al., 2002, Keleman et al., 2009.8.5, Ni et al., 2010.12.1) ida (Somma et al., 2008, Slack et al., 2007, Slack et al., 2006, Tanaka-Matakatsu et al., 2007, Buttitta et al., 2010, Silies and Klämbt, 2010, Neumüller et al., 2011) IDA (Acquaviva and Pines, 2006) l(3)63Fb (Vaskova et al., 2000, Harrison, 1999.5.12, ) l(3)SH7 (Harrison et al., 1995)
Name Synonym	imaginal discs arrested (Vaskova et al., 2000, Bentley et al., 2000, Slack et al., 2007, Slack et al., 2006)
Secondary FlyBase IDs
	FBgn0016008 FBgn0035472
References ( 32 )
Generate a list of	All references relating to this gene ( 32 )
List References by type	Research paper  ( 12 ) Supplementary material  ( 3 ) Review  ( 3 ) Personal communication to FlyBase  ( 8 ) Abstract  ( 3 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 1 )
Recent research papers ( 3 )
	Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593 Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi. [FBrf0213621] Buttitta et al., 2010, J. Cell Biol. 189(6): 981--996 A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo. [FBrf0211029] Silies and Klämbt, 2010, Nat. Neurosci. 13(11): 1357--1364 APC/C(Fzr/Cdh1)-dependent regulation of cell adhesion controls glial migration in the Drosophila PNS. [FBrf0212144] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...