FB2021_02, released April 13, 2021

Gene: Dmel\Slbp

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General Information
Symbol
Dmel\Slbp
Species
D. melanogaster
Name
Stem-loop binding protein
Annotation Symbol
CG11886
Feature Type
protein_coding_gene
FlyBase ID
FBgn0041186
Gene Model Status
Current
Stock Availability
9 publicly available
Gene Summary
Stem-loop binding protein (Slbp) encodes a protein that plays an essential role in 3' end processing of histone pre-mRNAs into mature histone mRNAs by recruiting the product of snRNA:U7 to the pre-mRNA. [Date last reviewed: 2018-11-08] (FlyBase Gene Snapshot)
All Summaries
Also Known As

dSLBP

Key Links
Genomic Location
Cytogenetic map
98F13-98F13
Sequence location
3R:29,152,074..29,153,266 [-]
Recombination map
3-97
RefSeq locus
NT_033777 REGION:29152074..29153266
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (10 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
enables protein binding
inferred from physical interaction with UniProtKB:Q8MSU4
(assigned by UniProt )
(Sullivan et al., 2009)
enables RNA stem-loop binding
inferred from direct assay
(Borchers et al., 2006, Sullivan et al., 2001)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables histone pre-mRNA stem-loop binding
inferred from biological aspect of ancestor with PANTHER:PTN000425771
(assigned by GO_Central )
(Gaudet et al., 2011)
enables mRNA binding
inferred from biological aspect of ancestor with PANTHER:PTN000425771
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
involved_in mitotic chromosome condensation
inferred from mutant phenotype
(Sullivan et al., 2001)
involved_in mRNA 3'-end processing by stem-loop binding and cleavage
inferred from direct assay
(Dominski et al., 2002)
inferred from mutant phenotype
(Sullivan et al., 2009, Wagner et al., 2007, Godfrey et al., 2006, Lanzotti et al., 2004, Sullivan et al., 2001)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in mRNA 3'-end processing by stem-loop binding and cleavage
inferred from biological aspect of ancestor with PANTHER:PTN000425771
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in mRNA transport
inferred from biological aspect of ancestor with PANTHER:PTN000425771
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
located_in cytoplasm
inferred from direct assay
(Lanzotti et al., 2004, Sullivan et al., 2001)
located_in nucleus
inferred from direct assay
(Lanzotti et al., 2004, Sullivan et al., 2001)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
located_in cytoplasm
inferred from biological aspect of ancestor with PANTHER:PTN000425771
(assigned by GO_Central )
(Gaudet et al., 2011)
part_of histone pre-mRNA 3'end processing complex
inferred from biological aspect of ancestor with PANTHER:PTN000425771
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the SLBP family. (Q9VAN6)
Protein Signatures (InterPro)
Summaries
Gene Snapshot
Stem-loop binding protein (Slbp) encodes a protein that plays an essential role in 3' end processing of histone pre-mRNAs into mature histone mRNAs by recruiting the product of snRNA:U7 to the pre-mRNA. [Date last reviewed: 2018-11-08]
Gene Group (FlyBase)
HISTONE MRNA 3' END PROCESSING FACTORS - ACCESSORY -
The histone pre-mRNA 3' end processing accessory group contains additional factors required for histone pre-mRNA processing. (Adapted from FBrf0223323).
Protein Function (UniProtKB)
Involved in histone pre-mRNA 3' processing and couples histone mRNA production with the cell cycle. Both maternal and zygotic proteins play an essential and vital function for development.
(UniProt, Q9VAN6)
Summary (Interactive Fly)

required for replication-dependent histone mRNA metabolism - 3' end cleavage of replication-dependent histone pre-mRNAs - promotes a structural rearrangement of the catalytically active U7-dependent processing complex, resulting in juxtaposition of an endonuclease with the cleavage site in the pre-mRNA substrate - oogenesis

Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Slbp for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.47

Gene model reviewed during 5.53

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Slbp-RA
FBtr0085409
NM_058132
1132
276
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
Slbp-PA
FBpp0084778
30.6
276
9.19
NP_477480
AAF56867
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)

276 (aa)

(Sullivan et al., 2001)
Comments
External Data
Subunit Structure (UniProtKB)

Interacts with Sym and Cpsf73.

(UniProt, Q9VAN6)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Slbp using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 7 -- 8
antennal anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
central brain anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
dorsal head epidermis anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
visual anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
anterior endoderm anlage
(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
hindgut anlage
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
posterior endoderm
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
ventral ectoderm
(Fisher et al., 2012)
embryonic stage 9 -- 10
antennal primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
central brain primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
visual primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
dorsal head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
lateral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
ventral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
inclusive hindgut primordium
(Fisher et al., 2012)
mesectoderm
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
ventral nerve cord primordium
(Fisher et al., 2012)
embryonic stage 11 -- 12
central brain primordium
(Fisher et al., 2012)
embryonic central brain neuron
(Fisher et al., 2012)
embryonic central brain surface glia
(Fisher et al., 2012)
embryonic ganglion mother cell
(Fisher et al., 2012)
embryonic neuroblast of ventral nerve cord primordium
(Fisher et al., 2012)
lateral cord glial cell
(Fisher et al., 2012)
lateral cord neuron
(Fisher et al., 2012)
lateral cord surface glial cell
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
procephalic neuroblast
(Fisher et al., 2012)
ventral nerve cord primordium
(Fisher et al., 2012)
embryonic stage 13 -- 16
embryonic brain
(Fisher et al., 2012)
embryonic central brain neuron
(Fisher et al., 2012)
embryonic central brain surface glia
(Fisher et al., 2012)
embryonic/larval lymph gland
(Fisher et al., 2012)
embryonic/larval nervous system
(Fisher et al., 2012)
lateral cord neuron
(Fisher et al., 2012)
lateral cord surface glial cell
(Fisher et al., 2012)
mushroom body primordium

Comment: reported as embryonic central brain mushroom body

(Fisher et al., 2012)
organism | faint | ubiquitous
(Fisher et al., 2012)
larval ventral nerve cord
(Fisher et al., 2012)
pcr
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage -- adult stage
(Sullivan et al., 2001)
pre-blastoderm stage
organism
(Sullivan et al., 2001)
embryonic stage 5 -- 12
organism | ubiquitous
(Sullivan et al., 2001)
embryonic stage 11 -- 17
presumptive embryonic/larval peripheral nervous system
(Sullivan et al., 2001)
presumptive embryonic/larval central nervous system
(Sullivan et al., 2001)
embryonic stage 13 -- 17
embryonic/larval midgut primordium
(Sullivan et al., 2001)
Additional Descriptive Data

Slbp transcript is detected in all developmental stages, with highest amounts in 0-8 hr embryos and adult females. Maternal Slbp transcript disappears by the end of the syncytial blastoderm stage. Ubiquitous zygotic expression begins at the cellular blastoderm stage, and is maintained during early germ-band extension. At later stages, expression decreases in G1 arrested cells and is restricted to proliferating and endoreduplicating cells.

(Sullivan et al., 2001)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in cytoplasm
inferred from direct assay
(Lanzotti et al., 2004, Sullivan et al., 2001)
located_in nucleus
inferred from direct assay
(Lanzotti et al., 2004, Sullivan et al., 2001)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Slbp in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 7-8
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 11 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 11 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Slbp
Transgenic constructs containing regulatory region of Slbp
Aberrations (Deficiencies and Duplications) ( 3 )
Inferred from experimentation ( 3 )
Gene disrupted in
Df(3R)3450
(Sullivan et al., 2001)
Df(3R)Slbp12
(Sullivan et al., 2001)
Df(3R)stgAR2
(Lanzotti et al., 2004)
Inferred from location ( 0 )
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\SLBP
10 of 15
Yes
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Slbp
9 of 15
Yes
Yes
Rattus norvegicus (Norway rat) (2)
Rnor\Slbp
6 of 13
Yes
Yes
Rnor\LOC100363294
3 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (2)
Xtro\slbp
6 of 12
Yes
Yes
Xtro\LOC100487104
1 of 12
No
Yes
Danio rerio (Zebrafish) (2)
Drer\slbp2
7 of 15
Yes
Yes
Drer\slbp
6 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\cdl-1
10 of 15
Yes
Yes
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190FUI )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00012300
Drosophila simulans
Dsim\GD15074
Drosophila sechellia
Dsec\GM12257
Drosophila erecta
Dere\GG12032
Drosophila yakuba
Dyak\GE10470
Drosophila ananassae
Dana\GF18411
Drosophila pseudoobscura pseudoobscura
Dpse\GA11260
Drosophila persimilis
Dper\GL23600
Drosophila willistoni
Dwil\GK22497
Drosophila willistoni
Dwil\GK22498
Drosophila virilis
Dvir\GJ14235
Drosophila mojavensis
Dmoj\GI22353
Drosophila grimshawi
Dgri\GH23225
Drosophila grimshawi
Dgri\GH14009
Drosophila grimshawi
Dgri\GH23223
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150DJS )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17025034
Mayetiola destructor
Hessian fly
Mdes\Mdes015108
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL010422
Anopheles darlingi
American malaria mosquito
Adar\ADAC004220
Anopheles gambiae
Malaria mosquito
Agam\AGAP012972
Anopheles gambiae
Malaria mosquito
Agam\AGAP013023
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ008644
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0J0I )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA005486
Danaus plexippus
Monarch butterfly
Dple\DPOGS207770-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL017568
Apis florea
Little honeybee
Aflo\4535098564
Apis mellifera
Western honey bee
Amel\GB46213
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP19428
Bombus terrestris
Buff-tailed bumblebee
Bter\15211081
Linepithema humile
Argentine ant
Lhum\LH18156
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:000a57
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG005729
Tribolium castaneum
Red flour beetle
Tcas\TC012536
Pediculus humanus
Human body louse
Phum\PHUM317680
Rhodnius prolixus
Kissing bug
Rpro\RPRC005874
Cimex lectularius
Bed bug
Clec\CLEC013448
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI001641
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_02726
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0NOU )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Ixodes scapularis
Black-legged tick
Isca\ISCW022471
Stegodyphus mimosarum
African social velvet spider
Smim\KFM65716.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur16g02660
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_45102
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0LT8 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Slbp_1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Slbp
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000025060
Gallus gallus
Domestic chicken
Ggal\SLBP
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (0)
No records found.
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    SLBP; stem-loop binding protein
    10 of 15
    602422
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        Summary of Genetic Interactions
        esyN Network Diagram
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        External Data
        Subunit Structure (UniProtKB)
        Interacts with Sym and Cpsf73.
        (UniProt, Q9VAN6 )
        Linkouts
        DroID - A comprehensive database of gene and protein interactions.
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        External Data
        Linkouts
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        3R
        Recombination map
        3-97
        Cytogenetic map
        98F13-98F13
        Sequence location
        3R:29,152,074..29,153,266 [-]
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        98F13-98F13
        Limits computationally determined from genome sequence between P{EP}EP3390EP3390 and P{PZ}l(3)0470804708
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        98F-98F
        (Duronio, 2000.2.2, Sullivan, 2000.4.19, Sullivan, 1999.8.12)
        Experimentally Determined Recombination Data
        Location

        3-97

        (FlyBase, 2016)

        3-94.8

        (Comeron et al., 2012)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (9)
        Genomic Clones (14)
         

        Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

        cDNA Clones (39)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequenced
        BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        DRSC - Results frm RNAi screens
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        Antibody Information
        Laboratory Generated Antibodies
         

        polyclonal

        (Iampietro et al., 2014, Sullivan et al., 2009, Sullivan et al., 2001)
        Commercially Available Antibodies
         
        Other Information
        Relationship to Other Genes
        Source for database identify of
        Source for database merge of

        Source for merge of: Slbp CG11886

        (FlyBase, 1996-)
        Additional comments

        Source for merge of Slbp CG11886 was sequence comparison ( date:000526 ).

        (FlyBase, 1996-)
        Other Comments

        Mutant analysis shows that phosphorylation of Slbp at T230 is necessary for its localization to the cytoplasm and subsequent function in the 3'-end processing of histone mRNA.

        (Lanzotti et al., 2004)

        Slbp is required for 3' end processing of histone pre-mRNA. Overall orientation not stated: Pglym78+ ligatin- Slbp- Rpn2+

        (Sullivan et al., 2001)

        Slbp-dependant processing plays an important role in coupling histone mRNA production with the cell cycle.

        (Sullivan et al., 2001)

        The pattern of histone mRNA accumulation is disrupted in mutant embryos.

        (Duronio et al., 2000)
        Origin and Etymology
        Discoverer
        Etymology
        Identification
        External Crossreferences and Linkouts ( 42 )
        Sequence Crossreferences
        NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
        GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
        GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
        RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
        UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
        Other crossreferences
        BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
        Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
        Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
        Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
        Flygut - An atlas of the Drosophila adult midgut
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
        InterPro - A database of protein families, domains and functional sites
        KEGG Genes - Molecular building blocks of life in the genomic space.
        modMine - A data warehouse for the modENCODE project
        Linkouts
        DPiM - Drosophila Protein interaction map
        DroID - A comprehensive database of gene and protein interactions.
        DRSC - Results frm RNAi screens
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
        FlyMine - An integrated database for Drosophila genomics
        Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Synonyms and Secondary IDs (12)
        Reported As
        Symbol Synonym
        CG11886
        (Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Brody et al., 2002)
        SLBP
        (Hur et al., 2020, Skrajna et al., 2018, Lefebvre et al., 2017, Lefebvre et al., 2017, Skrajna et al., 2017, Tatomer et al., 2014, Zhang et al., 2014, Sabath et al., 2013, Chen et al., 2012, Zhang et al., 2012, Ezzeddine et al., 2011, White et al., 2011, Sullivan et al., 2009, Tatomer et al., 2008, Wagner et al., 2008, Sofola et al., 2007, Wagner et al., 2007, Godfrey et al., 2006, Kupsco et al., 2006, Dominski et al., 2005, Godfrey et al., 2005)
        Slbp
        (Guan et al., 2019, Bischof and FlyORF project members, 2014.6.20, Hughes et al., 2014, Japanese National Institute of Genetics, 2012.5.21, Lafave and Sekelsky, 2011, Bulchand et al., 2010, Salzler et al., 2009, Wagner et al., 2007, White et al., 2007)
        dSLBP
        (Dankert et al., 2017, Li et al., 2012, Li et al., 2012, Yang et al., 2009, Borchers et al., 2006, Torres et al., 2005, Kupsco et al., 2004, Robertson et al., 2004, Thapar et al., 2004, Thapar et al., 2004, Dominski et al., 2003, Dominski et al., 2002, Lanzotti et al., 2002, Duronio et al., 2000)
        dSLPB
        (Sullivan et al., 2001)
        slbp
        (Terzo et al., 2015, Southall and Brand, 2009, Sofola et al., 2007, Orian et al., 2003)
        Name Synonyms
        Stem Loop Binding Protein
        (Torres et al., 2005)
        Stem-Loop Binding Protein
        (Zhang et al., 2012, Salzler et al., 2009, Torres et al., 2005)
        Stem-loop binding protein
        (Bulchand et al., 2010, Duronio et al., 2000)
        stem loop binding protein
        (Tatomer et al., 2014, Wagner et al., 2007)
        stem-loop binding protein
        (Tadros et al., 2007, Dominski et al., 2002)
        stem-loop-binding protein
        (Zhang et al., 2014)
        Secondary FlyBase IDs
        • FBgn0039643
        Datasets (0)
        Study focus (0)
        Experimental Role
        Project
        Project Type
        Title
        References (83)