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Gene Dmel\Gr22f

General Information
Symbol	Dmel\Gr22f	Species	D. melanogaster
Name	Gustatory receptor 22f	Annotation symbol	CG31932
Feature type	protein_coding_gene	FlyBase ID	FBgn0041249
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	Gr22B1
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	22B2-22B2	Sequence location	2L:1,755,253..1,756,451 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Gustatory receptor 22f is referred to in FlyBase by the symbol Dmel\Gr22f (CG31932, FBgn0041249). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: taste receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process: sensory perception of taste. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: 7TM chemoreceptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1625222_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Gr22f. Gene sequence location is 2L:1755253..1756451.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 22B2-22B2   Limits computationally determined from genome sequence between P{lacW}CG17646k11021 and P{EP}EP366
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Gr22f for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Gr22f-RA FBtr0077902  NM_164437   1137   378
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Gr22f-PA   FBpp0077568   44.4   378   8.90     NP_722729   AAN10461
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • 7TM chemoreceptor (IPR013604)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAN10461   AC003945   AX058711 CAC22540   EY198612
UniProtKB/Swiss-Prot	P58954
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References regulatory region FBsf0000435513 2L:1,756,458..1,758,495 evidence=Reporter construct (in vivo) (Dunipace et al., 2001, Halfon, 2012.6.19)
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
Reporter: P{Gr22f-GAL4.D} Stage Tissue/Position (including subcellular localization) Reference adult stage   labellar taste bristle | subset   (Dunipace et al., 2001) gustatory receptor neuron | subset   (Dunipace et al., 2001) gustatory receptor neuron of labellar taste bristle | subset   (Dunipace et al., 2001) chemosensory neuron of labellum   (Thorne et al., 2004)
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2.725 Larval Midgut    5.1 Larval Hindgut    3.1 Larval Malpighian Tubules    1.6 Larval Fat Body    4.9 Larval Salivary Gland    7.6 Larval Trachea    2.375 Larval Carcass    3.475 Adult Head    6.5 Adult Eye    2.1 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    2.8 Adult Crop    3.6 Adult Midgut    5.3 Adult Hindgut    4 Adult Malpighian Tubules    4.2 Adult Fat Body    3.1 Adult Salivary Gland    9.6 Adult Heart    0.875 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    1.8 Adult Ovary    1.9 Adult Testis    13.1 Adult Male Accessory Gland    6.9 Adult Carcass    7.2 Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.725 Larval Midgut    5.1 Larval Hindgut    3.1 Larval Malpighian Tubules    1.6 Larval Fat Body    4.9 Larval Salivary Gland    7.6 Larval Trachea    2.375 Larval Carcass    3.475 Adult Head    6.5 Adult Eye    2.1 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    2.8 Adult Crop    3.6 Adult Midgut    5.3 Adult Hindgut    4 Adult Malpighian Tubules    4.2 Adult Fat Body    3.1 Adult Salivary Gland    9.6 Adult Heart    0.875 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    1.8 Adult Ovary    1.9 Adult Testis    13.1 Adult Male Accessory Gland    6.9 Adult Carcass    7.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.725 Larval Midgut    5.1 Larval Hindgut    3.1 Larval Malpighian Tubules    1.6 Larval Fat Body    4.9 Larval Salivary Gland    7.6 Larval Trachea    2.375 Larval Carcass    3.475 Adult Head    6.5 Adult Eye    2.1 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    2.8 Adult Crop    3.6 Adult Midgut    5.3 Adult Hindgut    4 Adult Malpighian Tubules    4.2 Adult Fat Body    3.1 Adult Salivary Gland    9.6 Adult Heart    0.875 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    1.8 Adult Ovary    1.9 Adult Testis    13.1 Adult Male Accessory Gland    6.9 Adult Carcass    7.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.725 Larval Midgut    5.1 Larval Hindgut    3.1 Larval Malpighian Tubules    1.6 Larval Fat Body    4.9 Larval Salivary Gland    7.6 Larval Trachea    2.375 Larval Carcass    3.475 Adult Head    6.5 Adult Eye    2.1 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    2.8 Adult Crop    3.6 Adult Midgut    5.3 Adult Hindgut    4 Adult Malpighian Tubules    4.2 Adult Fat Body    3.1 Adult Salivary Gland    9.6 Adult Heart    0.875 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    1.8 Adult Ovary    1.9 Adult Testis    13.1 Adult Male Accessory Gland    6.9 Adult Carcass    7.2 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2.725 Larval Midgut    5.1 Larval Hindgut    3.1 Larval Malpighian Tubules    1.6 Larval Fat Body    4.9 Larval Salivary Gland    7.6 Larval Trachea    2.375 Larval Carcass    3.475 Adult Head    6.5 Adult Eye    2.1 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    2.8 Adult Crop    3.6 Adult Midgut    5.3 Adult Hindgut    4 Adult Malpighian Tubules    4.2 Adult Fat Body    3.1 Adult Salivary Gland    9.6 Adult Heart    0.875 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    1.8 Adult Ovary    1.9 Adult Testis    13.1 Adult Male Accessory Gland    6.9 Adult Carcass    7.2 Expression Level Scale  None   Low  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.725 Larval Midgut    5.1 Larval Hindgut    3.1 Larval Malpighian Tubules    1.6 Larval Fat Body    4.9 Larval Salivary Gland    7.6 Larval Trachea    2.375 Larval Carcass    3.475 Adult Head    6.5 Adult Eye    2.1 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    2.8 Adult Crop    3.6 Adult Midgut    5.3 Adult Hindgut    4 Adult Malpighian Tubules    4.2 Adult Fat Body    3.1 Adult Salivary Gland    9.6 Adult Heart    0.875 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    1.8 Adult Ovary    1.9 Adult Testis    13.1 Adult Male Accessory Gland    6.9 Adult Carcass    7.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.725 Larval Midgut    5.1 Larval Hindgut    3.1 Larval Malpighian Tubules    1.6 Larval Fat Body    4.9 Larval Salivary Gland    7.6 Larval Trachea    2.375 Larval Carcass    3.475 Adult Head    6.5 Adult Eye    2.1 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    2.8 Adult Crop    3.6 Adult Midgut    5.3 Adult Hindgut    4 Adult Malpighian Tubules    4.2 Adult Fat Body    3.1 Adult Salivary Gland    9.6 Adult Heart    0.875 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    1.8 Adult Ovary    1.9 Adult Testis    13.1 Adult Male Accessory Gland    6.9 Adult Carcass    7.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.725 Larval Midgut    5.1 Larval Hindgut    3.1 Larval Malpighian Tubules    1.6 Larval Fat Body    4.9 Larval Salivary Gland    7.6 Larval Trachea    2.375 Larval Carcass    3.475 Adult Head    6.5 Adult Eye    2.1 Adult Brain    4.4 Adult Thoracic-Abdominal Ganglion    2.8 Adult Crop    3.6 Adult Midgut    5.3 Adult Hindgut    4 Adult Malpighian Tubules    4.2 Adult Fat Body    3.1 Adult Salivary Gland    9.6 Adult Heart    0.875 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    1.8 Adult Ovary    1.9 Adult Testis    13.1 Adult Male Accessory Gland    6.9 Adult Carcass    7.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    6.5   NA  Eye    2.1   NA  Brain    4.4   2.725  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    2.8   NA  Crop    3.6   5.1  Midgut    5.3   3.1  Hindgut    4   1.6  Malpighian Tubules    4.2   4.9  Fat Body    3.1   7.6  Salivary Gland    9.6   NA  Heart    0.875   2.375  Trachea    NA   NA  VirginFemale Spermatheca    1.6   NA  InseminatedFemale Spermatheca    1.8   NA  Ovary    1.9   NA  Testis    13.1   NA  Male Accessory Gland    6.9   3.475  Carcass    7.2 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (Graveley et al., 2011) mE1_20_mRNA_expression_cluster_08
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0041249 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG31932-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 Gr22fGD810 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Gr22f Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Gr22f Class Mutagen Stocks Known lesion Gr22fGD810 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Gr22fKK105570 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7007 (Ryder, 2004.4.26) Df(2L)Exel8005 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD810} NA P{KK105570} NA GAL4 construct P{Gr22f-GAL4.2.5} No characterization construct P{Gr22f-GAL4.8.249} NA P{Gr22f-GAL4.D} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
taste receptor activity inferred from sequence or structural similarity (Clyne et al., 2000)
Biological Process
CV term Evidence References
sensory perception of taste inferred from electronic annotation with InterPro:IPR013604 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Clyne et al., 2000)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR013604 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Gr22f allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0041249
Orthologs
OrthoDB Orthologs (5) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6NGH6P Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6NGH6P)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Gr22f     Drosophila simulans   Dsim\GD22895 Y   Drosophila sechellia   Dsec\GM16594 Y   Drosophila erecta   Dere\GG24576 Y   Drosophila yakuba   Dyak\GE15434 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (4) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD22895 Drosophila sechellia Dsec\GM16594 Drosophila erecta Dere\GG24576 Drosophila yakuba Dyak\GE15434
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v102860 P{KK105570}VIE-260B v42745 w1118 P{GD810}v42745 v42744 w1118; P{GD810}v42744
Genomic Clones ( 2 )
	BACR19B15 BACR25P15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 0 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0041249 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 117349
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	New annotation (CG31932) in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_164437 RefSeq (Proteins) • NP_722729 DDBJ / EMBL / GenBank • AAN10461 AC003945 AX058711 CAC22540 Entrez Gene - A searchable database of RefSeq genes. • 117349 UniProtKB/Swiss-Prot • P58954
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • 7TM chemoreceptor (IPR013604)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0041249 DRSC - Results from RNAi screens. • FBgn0041249 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0041249 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG31932-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0041249 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 117349 modMine - Data generated by the modENCODE project. • FBgn0041249
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	22B.1 (Clyne et al., 2000) CG31932 (Keleman et al., 2009.8.5) Gr22B1 (Scott and Axel, 2001.4.25, Scott et al., 2001) GR22b1 (Smith, 2001) GR22B.1 (Clyne et al., 2000, ) Gr22f (Reiter et al., 2007, McBride et al., 2007, Inomata et al., 2008, Zhou et al., 2009, Moon et al., 2009, Weiss et al., 2011, Weiss et al., 2011, Thorne et al., 2005, Colomb et al., 2007)
Name Synonym	Gustatory receptor 22B.1 (Clyne et al., 2000) Gustatory receptor 22f (Robertson, 2001.11.11)
Secondary FlyBase IDs
	FBgn0051932
References ( 30 )
Generate a list of	All references relating to this gene ( 30 )
List References by type	Research paper  ( 13 ) Supplementary material  ( 4 ) Review  ( 3 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 1 ) Patent  ( 1 )
Recent research papers ( 1 )
	Weiss et al., 2011, Neuron 69(2): 258--272 The Molecular and Cellular Basis of Bitter Taste in Drosophila. [FBrf0212834] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...