Gene Dmel\CG18853

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General Information

Symbol

Dmel\CG18853

Species

D. melanogaster

Name

Annotation symbol

CG18853

Feature type

protein_coding_gene

FlyBase ID

FBgn0042173

Gene Model Status

Uncertain

Stock availability

1 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

43E18-43E18

Sequence location

2R:3,716,567..3,717,934 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG18853 (FBgn0042173).The gene has a gene model, but the supporting evidence is inconclusive. It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: deoxyribodipyrimidine photo-lyase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: DNA repair. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: DNA photolyase, FAD-binding/Cryptochrome, C-terminal; DNA photolyase, class 2; Uncharacterised domain UPF0066; Uncharacterised domain UPF0066, YaeB-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: No FlyAtlas data available because no Affy2 ProbeSet aligns to an exon of CG18853. Comments on Affy2 ProbeSet: No relevant information because no Affy2 ProbeSet aligns to an exon of CG18853. Gene sequence location is 2R:3716567..3717934.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

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Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

43E18-43E18

Limits computationally determined from genome sequence between P{EP}CanB2^EP774 and P{lacW}lin19^k01207&P{lacW}rnh1^k07624

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG18853 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.49

Chimeric gene (of phr and CG12822); may not be functional (FBrf0173220).

Gene model uncertain: chimeric gene created by local tandem duplication event.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG18853-RA

FBtr0089426

NM_165566

1157

330

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG18853-PA

FBpp0088442

38.5

330

8.78

NP_724615

AAG22302

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

DNA photolyase, FAD-binding/Cryptochrome, C-terminal (IPR005101)

DNA photolyase, class 2 (IPR008148)

Uncharacterised domain UPF0066, YaeB-like domain (IPR023370)

Uncharacterised domain UPF0066 (IPR001378)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

A1Z758

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		10
central nervous system, pupae P8		6
head, virgin 1-day female		5
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		8
head, mated 20-day female		4
head, mated 1-day male		13
head, mated 4-day male		11
head, mated 20-day male		15
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		4
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		1
fat body, white prepupae		2
fat body, pupae P8		1
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		12
ovary, mated 4-day female		14
testis, mated 4-day male		5
accessory gland, mated 4-day male		4
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		10
central nervous system, pupae P8		6
head, virgin 1-day female		5
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		8
head, mated 20-day female		4
head, mated 1-day male		13
head, mated 4-day male		11
head, mated 20-day male		15
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		4
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		1
fat body, white prepupae		2
fat body, pupae P8		1
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		12
ovary, mated 4-day female		14
testis, mated 4-day male		5
accessory gland, mated 4-day male		4
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		10
central nervous system, pupae P8		6
head, virgin 1-day female		5
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		8
head, mated 20-day female		4
head, mated 1-day male		13
head, mated 4-day male		11
head, mated 20-day male		15
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		4
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		1
fat body, white prepupae		2
fat body, pupae P8		1
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		12
ovary, mated 4-day female		14
testis, mated 4-day male		5
accessory gland, mated 4-day male		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		10
central nervous system, pupae P8		6
head, virgin 1-day female		5
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		8
head, mated 20-day female		4
head, mated 1-day male		13
head, mated 4-day male		11
head, mated 20-day male		15
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		4
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		1
fat body, white prepupae		2
fat body, pupae P8		1
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		12
ovary, mated 4-day female		14
testis, mated 4-day male		5
accessory gland, mated 4-day male		4
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		10
central nervous system, pupae P8		6
head, virgin 1-day female		5
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		8
head, mated 20-day female		4
head, mated 1-day male		13
head, mated 4-day male		11
head, mated 20-day male		15
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		4
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		1
fat body, white prepupae		2
fat body, pupae P8		1
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		12
ovary, mated 4-day female		14
testis, mated 4-day male		5
accessory gland, mated 4-day male		4
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		10
central nervous system, pupae P8		6
head, virgin 1-day female		5
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		8
head, mated 20-day female		4
head, mated 1-day male		13
head, mated 4-day male		11
head, mated 20-day male		15
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		4
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		1
fat body, white prepupae		2
fat body, pupae P8		1
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		12
ovary, mated 4-day female		14
testis, mated 4-day male		5
accessory gland, mated 4-day male		4
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		10
central nervous system, pupae P8		6
head, virgin 1-day female		5
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		8
head, mated 20-day female		4
head, mated 1-day male		13
head, mated 4-day male		11
head, mated 20-day male		15
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		4
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		1
fat body, white prepupae		2
fat body, pupae P8		1
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		12
ovary, mated 4-day female		14
testis, mated 4-day male		5
accessory gland, mated 4-day male		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		10
central nervous system, pupae P8		6
head, virgin 1-day female		5
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		8
head, mated 20-day female		4
head, mated 1-day male		13
head, mated 4-day male		11
head, mated 20-day male		15
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		4
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		1
fat body, white prepupae		2
fat body, pupae P8		1
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		12
ovary, mated 4-day female		14
testis, mated 4-day male		5
accessory gland, mated 4-day male		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		15
embryo 04-06hr		12
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		14
embryo 12-14hr		9
embryo 14-16hr		10
embryo 16-18hr		10
embryo 18-20hr		8
embryo 20-22hr		13
embryo 22-24hr		7
larva L1		15
larva L2		8
larva L3 12hr old		12
larva L3 puffstage 1-2		15
larva L3 puffstage 3-6		16
larva L3 puffstage 7-9		14
white prepupae new		10
white prepupae 12hr		18
white prepupae 24hr		16
pupae 2d postWPP		11
pupae 3d postWPP		9
pupae 4d postWPP		29
adult male 01day		13
adult male 05day		27
adult male 30day		9
adult female 01day		17
adult female 05day		26
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		15
embryo 04-06hr		12
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		14
embryo 12-14hr		9
embryo 14-16hr		10
embryo 16-18hr		10
embryo 18-20hr		8
embryo 20-22hr		13
embryo 22-24hr		7
larva L1		15
larva L2		8
larva L3 12hr old		12
larva L3 puffstage 1-2		15
larva L3 puffstage 3-6		16
larva L3 puffstage 7-9		14
white prepupae new		10
white prepupae 12hr		18
white prepupae 24hr		16
pupae 2d postWPP		11
pupae 3d postWPP		9
pupae 4d postWPP		(29)
adult male 01day		13
adult male 05day		(27)
adult male 30day		9
adult female 01day		17
adult female 05day		26
adult female 30day		(30)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		15
embryo 04-06hr		12
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		14
embryo 12-14hr		9
embryo 14-16hr		10
embryo 16-18hr		10
embryo 18-20hr		8
embryo 20-22hr		13
embryo 22-24hr		7
larva L1		15
larva L2		8
larva L3 12hr old		12
larva L3 puffstage 1-2		15
larva L3 puffstage 3-6		16
larva L3 puffstage 7-9		14
white prepupae new		10
white prepupae 12hr		18
white prepupae 24hr		16
pupae 2d postWPP		11
pupae 3d postWPP		9
pupae 4d postWPP		29
adult male 01day		13
adult male 05day		27
adult male 30day		9
adult female 01day		17
adult female 05day		26
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		15
embryo 04-06hr		12
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		14
embryo 12-14hr		9
embryo 14-16hr		10
embryo 16-18hr		10
embryo 18-20hr		8
embryo 20-22hr		13
embryo 22-24hr		7
larva L1		15
larva L2		8
larva L3 12hr old		12
larva L3 puffstage 1-2		15
larva L3 puffstage 3-6		16
larva L3 puffstage 7-9		14
white prepupae new		10
white prepupae 12hr		18
white prepupae 24hr		16
pupae 2d postWPP		11
pupae 3d postWPP		9
pupae 4d postWPP		29
adult male 01day		13
adult male 05day		27
adult male 30day		9
adult female 01day		17
adult female 05day		26
adult female 30day		30
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		15
embryo 04-06hr		12
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		14
embryo 12-14hr		9
embryo 14-16hr		10
embryo 16-18hr		10
embryo 18-20hr		8
embryo 20-22hr		13
embryo 22-24hr		7
larva L1		15
larva L2		8
larva L3 12hr old		12
larva L3 puffstage 1-2		15
larva L3 puffstage 3-6		16
larva L3 puffstage 7-9		14
white prepupae new		10
white prepupae 12hr		18
white prepupae 24hr		16
pupae 2d postWPP		11
pupae 3d postWPP		9
pupae 4d postWPP		29
adult male 01day		13
adult male 05day		27
adult male 30day		9
adult female 01day		17
adult female 05day		26
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		15
embryo 04-06hr		12
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		14
embryo 12-14hr		9
embryo 14-16hr		10
embryo 16-18hr		10
embryo 18-20hr		8
embryo 20-22hr		13
embryo 22-24hr		7
larva L1		15
larva L2		8
larva L3 12hr old		12
larva L3 puffstage 1-2		15
larva L3 puffstage 3-6		16
larva L3 puffstage 7-9		14
white prepupae new		10
white prepupae 12hr		18
white prepupae 24hr		16
pupae 2d postWPP		11
pupae 3d postWPP		9
pupae 4d postWPP		29
adult male 01day		13
adult male 05day		27
adult male 30day		9
adult female 01day		17
adult female 05day		26
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		15
embryo 04-06hr		12
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		14
embryo 12-14hr		9
embryo 14-16hr		10
embryo 16-18hr		10
embryo 18-20hr		8
embryo 20-22hr		13
embryo 22-24hr		7
larva L1		15
larva L2		8
larva L3 12hr old		12
larva L3 puffstage 1-2		15
larva L3 puffstage 3-6		16
larva L3 puffstage 7-9		14
white prepupae new		10
white prepupae 12hr		18
white prepupae 24hr		16
pupae 2d postWPP		11
pupae 3d postWPP		9
pupae 4d postWPP		29
adult male 01day		13
adult male 05day		27
adult male 30day		9
adult female 01day		17
adult female 05day		26
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		15
embryo 04-06hr		12
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		14
embryo 12-14hr		9
embryo 14-16hr		10
embryo 16-18hr		10
embryo 18-20hr		8
embryo 20-22hr		13
embryo 22-24hr		7
larva L1		15
larva L2		8
larva L3 12hr old		12
larva L3 puffstage 1-2		15
larva L3 puffstage 3-6		16
larva L3 puffstage 7-9		14
white prepupae new		10
white prepupae 12hr		18
white prepupae 24hr		16
pupae 2d postWPP		11
pupae 3d postWPP		9
pupae 4d postWPP		29
adult male 01day		13
adult male 05day		27
adult male 30day		9
adult female 01day		17
adult female 05day		26
adult female 30day		30
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		29
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		16
embryonic Kc167		32
embryonic S1		46
embryonic S3		30
leg disc CME L1		12
wing disc CME-W2		8
wing disc ML-DmD8		12
wing disc ML-DmD9		21
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		29
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		8
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		15
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		18
ovary fGS/OSS		55
ovary OSC		12
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(29)
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		16
embryonic Kc167		(32)
embryonic S1		(46)
embryonic S3		(30)
leg disc CME L1		12
wing disc CME-W2		8
wing disc ML-DmD8		12
wing disc ML-DmD9		21
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		(29)
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		8
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		15
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		18
ovary fGS/OSS		(55)
ovary OSC		12
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		29
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		16
embryonic Kc167		32
embryonic S1		46
embryonic S3		30
leg disc CME L1		12
wing disc CME-W2		8
wing disc ML-DmD8		12
wing disc ML-DmD9		21
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		29
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		8
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		15
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		18
ovary fGS/OSS		55
ovary OSC		12
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		29
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		16
embryonic Kc167		32
embryonic S1		46
embryonic S3		30
leg disc CME L1		12
wing disc CME-W2		8
wing disc ML-DmD8		12
wing disc ML-DmD9		21
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		29
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		8
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		15
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		18
ovary fGS/OSS		55
ovary OSC		12
ovary OSS		4
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		29
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		16
embryonic Kc167		32
embryonic S1		46
embryonic S3		30
leg disc CME L1		12
wing disc CME-W2		8
wing disc ML-DmD8		12
wing disc ML-DmD9		21
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		29
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		8
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		15
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		18
ovary fGS/OSS		55
ovary OSC		12
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		29
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		16
embryonic Kc167		32
embryonic S1		(46)
embryonic S3		30
leg disc CME L1		12
wing disc CME-W2		8
wing disc ML-DmD8		12
wing disc ML-DmD9		21
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		29
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		8
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		15
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		18
ovary fGS/OSS		(55)
ovary OSC		12
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		29
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		16
embryonic Kc167		32
embryonic S1		46
embryonic S3		30
leg disc CME L1		12
wing disc CME-W2		8
wing disc ML-DmD8		12
wing disc ML-DmD9		21
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		29
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		8
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		15
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		18
ovary fGS/OSS		55
ovary OSC		12
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		29
Schneider line 2 Sg4		16
embryonic 1182-4H		17
embryonic GM2		16
embryonic Kc167		32
embryonic S1		46
embryonic S3		30
leg disc CME L1		12
wing disc CME-W2		8
wing disc ML-DmD8		12
wing disc ML-DmD9		21
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		29
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		8
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		15
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		18
ovary fGS/OSS		55
ovary OSC		12
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		7
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		5
Cadmium 50 mM 48 hrs, 4-day adult		9
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		4
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		18
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		7
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		18
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		13
Paraquat 10 mM 48 hrs, 4-day adult		16
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		7
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		7
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		5
Cadmium 50 mM 48 hrs, 4-day adult		9
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		4
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		18
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		7
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		18
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		13
Paraquat 10 mM 48 hrs, 4-day adult		16
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		7
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		7
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		5
Cadmium 50 mM 48 hrs, 4-day adult		9
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		4
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		18
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		7
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		18
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		13
Paraquat 10 mM 48 hrs, 4-day adult		16
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		7
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		5
Cadmium 50 mM 48 hrs, 4-day adult		9
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		4
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		18
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		7
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		18
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		13
Paraquat 10 mM 48 hrs, 4-day adult		16
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		7
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		7
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		5
Cadmium 50 mM 48 hrs, 4-day adult		9
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		4
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		18
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		7
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		18
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		13
Paraquat 10 mM 48 hrs, 4-day adult		16
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		7
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		7
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		5
Cadmium 50 mM 48 hrs, 4-day adult		9
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		4
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		18
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		7
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		18
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		13
Paraquat 10 mM 48 hrs, 4-day adult		16
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		7
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		7
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		5
Cadmium 50 mM 48 hrs, 4-day adult		9
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		4
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		18
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		7
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		18
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		13
Paraquat 10 mM 48 hrs, 4-day adult		16
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		7
heat shock, 4-day adult		11
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		5
Cadmium 50 mM 48 hrs, 4-day adult		9
Cadmium 100 mM 48 hrs, 4-day adult		16
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		4
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		18
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		7
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		18
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		13
Paraquat 10 mM 48 hrs, 4-day adult		16
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0042173

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG11205-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

CG18853^EY10700

Sterility

Allele

fertile

CG18853^EY10700

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG18853	Class	Mutagen	Stocks	Known lesion
CG18853^EY10700		P-element activity	1	--

Alleles Carried on Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG18853	Class	Mutagen	Stocks	Known lesion

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EPgy2}CG18853^EY10700

Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 2 terms )

Molecular Function

CV term

Evidence

References

deoxyribodipyrimidine photo-lyase activity

inferred from electronic annotation with InterPro:IPR008148

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

DNA repair

inferred from electronic annotation with InterPro:IPR005101, InterPro:IPR008148

(FlyBase Curators et al., 2004-)

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG18853 allele

Gene

References

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0042173

Orthologs

OrthoDB Orthologs (19) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

No orthologs identified

Dipteran inclusive ortholog search

No orthologs identified

Insect inclusive ortholog search

EOG6MCVVC

Arthropod inclusive ortholog search

EOG6V41PR

Metazoa inclusive ortholog search

EOG6WHNCX

Orthologs in Drosophila Species (None identified)

No orthologies identified

Orthologs in non-Drosophila Dipterans (None identified)

No non-Drosophilid orthologies identified

Orthologs in non-Dipteran Insects (EOG6MCVVC)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB53196

Apis mellifera

Western honey bee

Amel\GB46988

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG030688

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH17512

Atta cephalotes

Leafcutter ant

Acep\ACEP12937

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO22912

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL14354

Linepithema humile

Argentine ant

Lhum\LH19178

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB18344

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI003470

Bombyx mori

Silkmoth

Bmor\BGIBMGA013897

Pediculus humanus

Human body louse

Phum\PHUM370960

Tribolium castaneum

Red flour beetle

Tcas\TC030545

Orthologs in non-Insect Arthropods (EOG6V41PR)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Ixodes scapularis

Deer tick

Isca\ISCW014570

Orthologs in non-Arthropod Metazoa (EOG6WHNCX)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_001597gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_024091gn

Danio rerio

Zebrafish

Drer\zgc:66475

Xenopus tropicalis

Western clawed frog

Xtro\ENSXETG00000033241

Gallus gallus

Domestic chicken

Ggal\LOC424919

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (0) based on analysis using Dmel annotation version 4.3

No orthologs identified

Stocks & Reagents

Stocks Listed in FlyBase ( 1 )

Bloomington

20203

y¹ w^67c23; P{EPgy2}CG18853^EY10700

Genomic Clones ( 1 )

BACR04B09

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 54 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

IP05430

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0042173

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

246511

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

CG18853 appears to be a chimeric gene, with the 5' part of the gene derived from CG12822 and the 3' part of the gene derived from phr.

(Rogers and Hartl, 2012)

"CG18853" is a putative chimeric gene derived from the "CG12822" and "phr" genes (where coding sequences of the two parental genes contribute to the coding sequence of the chimeric gene).

(Rogers et al., 2009)

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_165566

RefSeq (Proteins)

•

NP_724615

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

246511

UniProtKB/TrEMBL

•

A1Z758

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

DNA photolyase, FAD-binding/Cryptochrome, C-terminal (IPR005101)

DNA photolyase, class 2 (IPR008148)

Uncharacterised domain UPF0066, YaeB-like domain (IPR023370)

Uncharacterised domain UPF0066 (IPR001378)

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0042173

DRSC - Results from RNAi screens.

•

FBgn0042173

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0042173

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG11205-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0042173

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

246511

modMine - Data generated by the modENCODE project.

•

FBgn0042173

Synonyms & Secondary IDs ( 3 )

Reported As

Symbol Synonym

143303_at

(Kristensen et al., 2005)

CG18853

(Rogers and Hartl, 2012, Zraly et al., 2006, Zhan et al., 2011)

CG18853-PA

(Rogers et al., 2009)

Name Synonym

Secondary FlyBase IDs

References ( 14 )

Research paper

Rogers and Hartl, 2012, Mol. Biol. Evol. 29(2): 517--529: Chimeric Genes as a Source of Rapid Evolution in Drosophila melanogaster. [FBrf0217452]
Zhan et al., 2011, Gene 470(1-2): 1--6: Evolution of alternative splicing in newly evolved genes of Drosophila. [FBrf0212278]
Blanco et al., 2010, BMC Dev. Biol. 10: 94: Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812]
Rogers et al., 2009, Genetics 181(1): 313--322: Formation and longevity of chimeric and duplicate genes in Drosophila melanogaster. [FBrf0207085]
Zraly et al., 2006, J. Biol. Chem. 281(46): 35305--35315: Hormone-response genes are direct in vivo regulatory targets of Brahma (SWI/SNF) complex function. [FBrf0192654]
Kristensen et al., 2005, Genetics 171(1): 157--167: Genome-wide analysis on inbreeding effects on gene expression in Drosophila melanogaster. [FBrf0187643]

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]

Personal communication to FlyBase

FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
Torroja, 2003.10.29, FlyBase error report for CG18853 on Wed Oct 29 08:59:30 2003.: FlyBase error report for CG18853 on Wed Oct 29 08:59:30 2003. [FBrf0173220]
Gene Disruption Project members, 2001-, (Computer file): (Computer file) [FBrf0132177]
Levis, 2001.5.22, CG12822 and CG18853 - one or two genes?: CG12822 and CG18853 - one or two genes? [FBrf0138594]

FlyBase analysis

FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome.: Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]