Beach1, EP2299, Beached, DBEACH1
Please see the JBrowse view of Dmel\bchs for information on other features
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Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.45
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\bchs using the Feature Mapper tool.
qRT-PCR of adult female heads assayed at weekly intervals shows that transcript levels decline significantly by 3 weeks and remain supressed.
bchs protein is expressed in the embryonic CNS from stage 12 on. It is observed in the longitudinal connectives and in a subset of neuronal cell bodies that lie between the commissures including the aCC and RP2 motor neurons. It is also observed at low levels throughout the CNS, in muscles, and in some other tissues.
GBrowse - Visual display of RNA-Seq signals
View Dmel\bchs in GBrowse 22-18
2-18
2-19.2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Beach1 bchs
Source for merge of: Beach1 CG9011 CG14001 EP2299
Source for merge of: Beach1 BcDNA:SD12984
Source for merge of Beach1 BcDNA:SD12984 was a shared cDNA ( date:030728 ).
bchs may have some role in determining cellular volume and/or proliferation in the brain.
Identification: in a screen for genes which when overexpressed cause motorneuron pathfinding and or synaptogenesis errors.
Involved in endocytosis/membrane trafficking.