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Gene Dsim\ocn

General Information
Symbol	Dsim\ocn	Species	D. simulans
Name	ocnus	Annotation symbol	GD17421
Feature type	protein_coding_gene	FlyBase ID	FBgn0043621
Gene Model Status	Current	Stock availability	None publicly available
Also Known As	Ocn
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map		Sequence location	3R:25,529,601..25,530,158 [-]
Genomic Maps	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene ocnus is referred to in FlyBase by the symbol Dsim\ocn (GD17421, FBgn0043621). It is a protein_coding_gene from Drosophila simulans. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide. Protein features are: Janus/Ocnus. Gene sequence location is 3R:25529601..25530158.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dsim\ocn for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Dsim\ocn-RA FBtr0217331  XM_002105417   447   148
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Dsim\ocn-PA   FBpp0215823   16.9   148   10.51     XP_002105453   EDX14956
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Janus/Ocnus (IPR007702)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AF393356 AAK72034   AF393357 AAK72035   AF393358 AAK72036   AF393359 AAK72037   AF393360 AAK72038   AF393361 AAK72039   AF393362 AAK72040   AF393363 AAK72041   AF393364 AAK72042   AF393365 AAK72043   AF393366 AAK72044   AF393367 AAK72045   AF393368 AAK72046   AY013352 AAG50373   AY663155 AAU44645   AY663156 AAU44646   AY663157 AAU44647   AY663158 AAU44648   AY663159 AAU44649   AY663160 AAU44650   AY663161 AAU44651   AY663162 AAU44652   AY663163 AAU44653   AY663164 AAU44654   AY663165 AAU44655   AY663166 AAU44656   AY663167 AAU44657   AY663168 AAU44658   AY663169 AAU44659   AY663170 AAU44660   AY663171 AAU44661   AY663172 AAU44662   AY663173 AAU44663   AY663174 AAU44664   AY663175 AAU44665   AY663176 AAU44666   CM000364 EDX14956
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	B4R0Y5 Q9BM88
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Dsim\ocn Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Dsim\ocn Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene   nuclear_gene (Drosophila 12 Genomes Consortium, 2008) protein_coding_gene (Drosophila 12 Genomes Consortium, 2008)
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Dsim\ocn allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (2) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6GXG79 Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Ortholog(s) in Drosophila melanogaster (EOG6GXG79)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\janB     Drosophila melanogaster fruit fly  Dmel\ocn
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 0 )
cDNA Clones ( 0 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • XM_002105417 RefSeq (Proteins) • XP_002105453 DDBJ / EMBL / GenBank • AAG50373 AAK72034 AAK72035 AAK72036 AAK72037 AAK72038 AAK72039 AAK72040 AAK72041 AAK72042 AAK72043 AAK72044 AAK72045 AAK72046 AAU44645 AAU44646 AAU44647 AAU44648 AAU44649 AAU44650 AAU44651 AAU44652 AAU44653 AAU44654 AAU44655 AAU44656 AAU44657 AAU44658 AAU44659 AAU44660 AAU44661 AAU44662 AAU44663 AAU44664 AAU44665 AAU44666 AF393356 AF393357 AF393358 AF393359 AF393360 AF393361 AF393362 AF393363 AF393364 AF393365 AF393366 AF393367 AF393368 AY013352 AY459539 AY663155 AY663156 AY663157 AY663158 AY663159 AY663160 AY663161 AY663162 AY663163 AY663164 AY663165 AY663166 AY663167 AY663168 AY663169 AY663170 AY663171 AY663172 AY663173 AY663174 AY663175 AY663176 EDX14956 Entrez Gene - A searchable database of RefSeq genes. • 6730162 UniProtKB/TrEMBL • B4R0Y5 Q9BM88
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Janus/Ocnus (IPR007702)
Linkouts
	FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0043621
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	dsim_GLEANR_1755 (Drosophila 12 Genomes Consortium, 2008) Dsim\ocn (Drosophila 12 Genomes Consortium, 2008, ) Ocn (Halligan, 2003.11.6) ocn (Drosophila 12 Genomes Consortium, 2008, Keightley and Johnson, 2004)
Name Synonym	ocnus (Parsch et al., 2001)
Secondary FlyBase IDs
References ( 15 )
Research paper	Legrand et al., 2011, Mol. Ecol. 20(13): 2787--2804 Inter-island divergence within Drosophila mauritiana, a species of the D. simulans complex: Past history and/or speciation in progress? [FBrf0214005] Drosophila 12 Genomes Consortium et al., 2007, Nature 450(7167): 203--218 Evolution of genes and genomes on the Drosophila phylogeny. [FBrf0200326] Jensen et al., 2005, Genetics 170(3): 1401--1410 Distinguishing between selective sweeps and demography using DNA polymorphism data. [FBrf0191495] Keightley and Johnson, 2004, Genome Res. 14(3): 442--450 MCALIGN: stochastic alignment of noncoding DNA sequences based on an evolutionary model of sequence evolution. [FBrf0174724] Meiklejohn et al., 2004, Genetics 168(1): 265--279 Identification of a locus under complex positive selection in Drosophila simulans by haplotype mapping and composite-likelihood estimation. [FBrf0180293] Parsch, 2003, Genetics 165(4): 1843--1851 Selective constraints on intron evolution in Drosophila. [FBrf0167646] Parsch et al., 2001, Mol. Biol. Evol. 18(5): 801--811 Molecular evolution of the ocnus and janus genes in the Drosophila melanogaster species subgroup. [FBrf0135889] Parsch et al., 2001, Genetics 159(2): 647--657 Patterns of DNA sequence variation suggest the recent action of positive selection in the janus-ocnus region of Drosophila simulans. [FBrf0139683]
Review	Singh, 2005, BioEssays 27(5): 518--525 [title not yet available] [FBrf0188535]
Personal communication to FlyBase	Drosophila 12 Genomes Consortium, 2008, personal communication to FlyBase Symbols and class of gene information for the GLEANR consensus sequences of the 11 sequenced non-melanogaster Drosophila species (Drosophila ananassae, erecta, grimshawi, mojavensis, persimilis, pseudoobscura, sechellia, simulans, willistoni, virilis and yakuba). [FBrf0202436]
Abstract	Parsch et al., 2002, A. Dros. Res. Conf. 43: 863B Patterns of DNA sequence variation suggest the recent action of positive selection in the janus-ocnus region of Drosophila simulans. [FBrf0145698] Meiklejohn et al., 2001, A. Dros. Res. Conf. 42: 869B Molecular Evolution of the ocnus and janus genes in the Drosophila melanogaster species subgroup. [FBrf0133808]
FlyBase analysis	FlyBase, 2008, Newly sequenced Drosophila genomes: associations of GLEANR gene predictions (Releases 1.0) with previously known genes in FlyBase. Newly sequenced Drosophila genomes: associations of GLEANR gene predictions (Releases 1.0) with previously known genes in FlyBase. [FBrf0202439]
DNA/RNA sequence record	Halligan, 2003.11.6, GenBank/EMBL/DDBJ: AY459539 Drosophila simulans Ocn 5' flanking region; and janusB gene, partial cds. [FBrf0171749] Parsch, 2000.11.9, GenBank/EMBL/DDBJ: AY013352 Drosophila simulans ocnus (ocn) gene, exons 1 through 3 and partial cds. [FBrf0133028]