FlyBase Gene Report: Dmel\CG30427

General Information

Symbol

Dmel\CG30427

Species

D. melanogaster

Name

Annotation Symbol

CG30427

Feature Type

protein_coding_gene

FlyBase ID

FBgn0043792

Gene Model Status

Current

Stock Availability

4 publicly available

Gene Snapshot

CG30427 encodes a fatty-acyl-CoA reductase involved in production of NADPH, sensory perception of pain, phagocytosis and determination of lifespan. [Date last reviewed: 2019-03-07]

Other Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

BEST:LD36843

Key Links

Genomic Location

Cytogenetic map

60E5-60E5

Sequence location

2R:24,928,747..24,937,477 [-]

Recombination map

2-107

RefSeq locus

NT_033778 REGION:24928747..24937477

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (5 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables fatty-acyl-CoA reductase (alcohol-forming) activity

inferred from biological aspect of ancestor with PANTHER:PTN000110226

(assigned by GO_Central )

(Gaudet et al., 2011)

inferred from sequence or structural similarity with HGNC:26222

(Faust et al., 2012)

Biological Process (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in determination of adult lifespan

inferred from mutant phenotype

(Paik et al., 2012)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in long-chain fatty-acyl-CoA metabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000110226

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

located_in intracellular membrane-bounded organelle

inferred from biological aspect of ancestor with PANTHER:PTN000110226

(assigned by GO_Central )

(Gaudet et al., 2011)

located_in peroxisome

inferred from biological aspect of ancestor with PANTHER:PTN000110227

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

FATTY ACYL-COA REDUCTASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

FATTY ACYL-COA REDUCTASES -: Fatty acyl-CoA reductases (FARs) catalyze the reduction of acyl-CoA to alcohols and aldehydes. In insects, they are involved in synthesis of cuticular hydrocarbons. (Adapted from FBrf0242506.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\CG30427 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.40

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.52

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

CG30427-RA

FBtr0072415

NM_166698

1678

499

CG30427-RB

FBtr0072414

NM_138136

1806

499

CG30427-RC

FBtr0072413

NM_166697

1852

506

CG30427-RD

FBtr0072416

NM_166699

1611

499

CG30427-RE

FBtr0300956

NM_001169827

2870

499

CG30427-RF

FBtr0300957

NM_001169828

1739

499

CG30427-RG

FBtr0309244

NM_001259583

1785

506

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

CG30427-PA

FBpp0072321

57.5

499

7.51

NP_726499

AAF47295

CG30427-PB

FBpp0072320

57.5

499

8.13

NP_611980

AAF47294

CG30427-PC

FBpp0072319

58.4

506

8.72

NP_726498

AAM70799

CG30427-PD

FBpp0072322

57.5

499

7.51

NP_726500

AAM70800

CG30427-PE

FBpp0290178

57.5

499

8.13

NP_001163298

ACZ94570

CG30427-PF

FBpp0290179

57.5

499

8.13

NP_001163299

ACZ94571

CG30427-PG

FBpp0301183

58.4

506

8.72

NP_001246512

AFH08265

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

506 aa isoforms: CG30427-PC, CG30427-PG

499 aa isoforms: CG30427-PB, CG30427-PE, CG30427-PF

499 aa isoforms: CG30427-PA, CG30427-PD

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CG30427 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

expression microarray

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | male

(Arbeitman et al., 2004)

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 9 -- 10

antennal primordium