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Gene Dmel\CG30427

General Information
Symbol	Dmel\CG30427	Species	D. melanogaster
Name		Annotation symbol	CG30427
Feature type	protein_coding_gene	FlyBase ID	FBgn0043792
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	60E5-60E5	Sequence location	2R:20,816,270..20,824,994 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG30427 (FBgn0043792). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: nucleotide binding; fatty-acyl-CoA reductase (alcohol-forming) activity. There is experimental evidence that it is involved in the biological process: determination of adult lifespan; phagocytosis, engulfment. 7 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Fatty acyl-CoA reductase; Male sterility, NAD-binding; NAD(P)-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult crop, larval trachea, larval/adult carcass. Gene sequence location is 2R:20816270..20824994.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 60E5-60E5   Limits computationally determined from genome sequence between P{EP}CG9047EP560&P{EP}CG3760EP936 and P{EP}CG2790EP412&P{EP}CG3776EP835
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG30427 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.40
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG30427-RA FBtr0072415  NM_166698   1672   499 CG30427-RB FBtr0072414  NM_138136   1800   499 CG30427-RC FBtr0072413  NM_166697   1846   506 CG30427-RD FBtr0072416  NM_166699   1611   499 CG30427-RE FBtr0300956  NM_001169827   2864   499 CG30427-RF FBtr0300957  NM_001169828   1739   499 CG30427-RG FBtr0309244  NM_001259583   1785   506
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG30427-PA   FBpp0072321   57.5   499   7.51     NP_726499   AAF47295 CG30427-PB   FBpp0072320   57.5   499   8.13     NP_611980   AAF47294 CG30427-PC   FBpp0072319   58.4   506   8.72     NP_726498   AAM70799 CG30427-PD   FBpp0072322   57.5   499   7.51     NP_726500   AAM70800 CG30427-PE   FBpp0290178   57.5   499   8.13     NP_001163298   ACZ94570 CG30427-PF   FBpp0290179   57.5   499   8.13     NP_001163299   ACZ94571 CG30427-PG   FBpp0301183   58.4   506   8.72     NP_001246512   AFH08265
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Male sterility, NAD-binding (IPR013120) NAD(P)-binding domain (IPR016040) Fatty acyl-CoA reductase (IPR026055)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF47294   AE013599 AAF47295   AE013599 AAM70799   AE013599 AAM70800   AE013599 ACZ94570   AE013599 ACZ94571   AE013599 AFH08265   AI456727   AI520277   AW943358   AY051874 AAK93298   AY119055   BG633172   BI162293   BI162294   BI171112   BI172383   BI215122   BI215275   BI238349   BI240390   BI240959   BI241408   BI241486   BI241597   BI364608   BI483156   BI483159   BI483227   BI590457   BI590476   BI614469   BT021335 AAX33483   BT053697   BT125121   BT133449   CO187888   CO188379   CO190336   CO267804   CO269667   CO285156   CO287511   CO301895   CO311707   CO326121   CO332179   CO339257   CZ466916   CZ466917   CZ482527   CZ488277   EC058029   EC073778   EC084691   EC087758   EC200857   EC223233   EC223332   EC228180   EC229556   EC253057   EC260017   EV582173   GR705729
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8MMC6 Q9W0Y5 Q0E8W1 Q5BI89
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
expression microarray Stage Tissue/Position (including subcellular localization) Reference adult stage | male     (Arbeitman et al., 2004) in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 9 -- 10   antennal primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium central brain primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium visual primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium dorsal head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium lateral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium ventral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium embryonic stage 13 -- 16   adult foregut precursor   (Fisher et al., 2012) adult hindgut precursor   (Fisher et al., 2012) embryonic dorsal epidermis   (Fisher et al., 2012) embryonic head epidermis   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic proventriculus   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012) embryonic/larval posterior spiracle   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult crop, larval trachea, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    3 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    2 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    19 carcass, larvae L3 wandering    4 carcass, 1-day adult    12 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    2 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    3 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    2 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    19 carcass, larvae L3 wandering    4 carcass, 1-day adult    12 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    2 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    3 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    2 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    19 carcass, larvae L3 wandering    4 carcass, 1-day adult    12 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    2 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    3 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    2 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    19 carcass, larvae L3 wandering    4 carcass, 1-day adult    12 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    2 accessory gland, mated 4-day male    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    3 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    2 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    19 carcass, larvae L3 wandering    4 carcass, 1-day adult    12 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    2 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    3 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    2 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    19 carcass, larvae L3 wandering    4 carcass, 1-day adult    12 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    2 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    3 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    2 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    19 carcass, larvae L3 wandering    4 carcass, 1-day adult    12 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    2 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    3 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    2 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    19 carcass, larvae L3 wandering    4 carcass, 1-day adult    12 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    2 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    26 embryo 16-18hr    134 embryo 18-20hr    60 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    5 larva L2    43 larva L3 12hr old    32 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    3 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    4 pupae 2d postWPP    14 pupae 3d postWPP    76 pupae 4d postWPP    11 adult male 01day    37 adult male 05day    35 adult male 30day    22 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr  26 embryo 16-18hr  (134) embryo 18-20hr  (60) embryo 20-22hr    9 embryo 22-24hr    11 larva L1    5 larva L2  (43) larva L3 12hr old  (32) larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    3 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    4 pupae 2d postWPP    14 pupae 3d postWPP  (76) pupae 4d postWPP    11 adult male 01day  (37) adult male 05day  (35) adult male 30day    22 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    26 embryo 16-18hr  (134) embryo 18-20hr    60 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    5 larva L2    43 larva L3 12hr old    32 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    3 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    4 pupae 2d postWPP    14 pupae 3d postWPP    76 pupae 4d postWPP    11 adult male 01day    37 adult male 05day    35 adult male 30day    22 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    26 embryo 16-18hr    134 embryo 18-20hr    60 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    5 larva L2    43 larva L3 12hr old    32 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    3 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    4 pupae 2d postWPP    14 pupae 3d postWPP    76 pupae 4d postWPP    11 adult male 01day    37 adult male 05day    35 adult male 30day    22 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    26 embryo 16-18hr    134 embryo 18-20hr    60 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    5 larva L2    43 larva L3 12hr old    32 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    3 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    4 pupae 2d postWPP    14 pupae 3d postWPP    76 pupae 4d postWPP    11 adult male 01day    37 adult male 05day    35 adult male 30day    22 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr  26 embryo 16-18hr  (134) embryo 18-20hr  (60) embryo 20-22hr    9 embryo 22-24hr    11 larva L1    5 larva L2  (43) larva L3 12hr old  32 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    3 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    4 pupae 2d postWPP    14 pupae 3d postWPP  (76) pupae 4d postWPP    11 adult male 01day  (37) adult male 05day  (35) adult male 30day    22 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    26 embryo 16-18hr  134 embryo 18-20hr    60 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    5 larva L2    43 larva L3 12hr old    32 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    3 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    4 pupae 2d postWPP    14 pupae 3d postWPP    76 pupae 4d postWPP    11 adult male 01day    37 adult male 05day    35 adult male 30day    22 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    26 embryo 16-18hr    134 embryo 18-20hr    60 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    5 larva L2    43 larva L3 12hr old    32 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    3 white prepupae new    1 white prepupae 12hr    2 white prepupae 24hr    4 pupae 2d postWPP    14 pupae 3d postWPP    76 pupae 4d postWPP    11 adult male 01day    37 adult male 05day    35 adult male 30day    22 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_18
External Data & Images
Linkouts	BDGP expression data • LD36843 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0043792 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30427-RA;CG30427-RB;CG30427-RC FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG30427 Stages(s) 9-10 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG30427GD2222 Other Phenotypes Allele long lived, with Scer\GAL4da.Switch.PT CG30427EP22086 Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of CG30427 Class Mutagen Stocks Known lesion CG30427c01123 piggyBac transposase 1 -- CG30427f00041 piggyBac transposase 1 -- CG30427f05660 piggyBac transposase 1 -- CG30427MB12237 1 -- CG30427EP22086 Delta2-3 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG30427 Class Mutagen Stocks Known lesion CG30427GD2222 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG30427KK111350 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2222} NA P{KK111350} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG30427EP22086 NA P{EP}painEP2174 NA P{EP}painEP2251 NA P{EP}painEP2451 NA P{EP}painEP2462 NA P{EP}painEP2621 NA P{EPgy2}EY01775 NA miscellaneous insertions PBac{PB}CG30427c01123 NA PBac{WH}CG30427f00041 NA PBac{WH}CG30427f05660 NA insertion of enhancer trap binary system Mi{ET1}CG30427MB12237 No
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
determination of adult lifespan inferred from mutant phenotype (Paik et al., 2012) phagocytosis, engulfment inferred from mutant phenotype (Stroschein-Stevenson et al., 2006)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
fatty-acyl-CoA reductase (alcohol-forming) activity inferred from electronic annotation with InterPro:IPR026055 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG30427 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63554 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0043792 DroID - A comprehensive database of gene and protein interactions. • FBgn0043792 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37986
Orthologs
OrthoDB Orthologs (105) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG693438 Dipteran inclusive ortholog search EOG63FH5C Insect inclusive ortholog search EOG6P5J5P Arthropod inclusive ortholog search EOG6JH9X6 Metazoa inclusive ortholog search EOG6PCPKS
Orthologs in Drosophila Species (EOG693438)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG30427     Drosophila simulans   Dsim\GD24908 Y   Drosophila sechellia   Dsec\GM11778 Y   Drosophila erecta   Dere\GG19877 Y   Drosophila yakuba   Dyak\GE11401 Y   Drosophila ananassae   Dana\GF11526 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA24528 Y   Drosophila persimilis   Dper\GL10898     Drosophila willistoni   Dwil\GK20732 Y   Drosophila virilis   Dvir\GJ22269 Y   Drosophila mojavensis   Dmoj\GI19136 Y   Drosophila grimshawi   Dgri\GH22050 Y
Orthologs in non-Drosophila Dipterans (EOG63FH5C)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014302   Anopheles gambiae Malaria mosquito  Agam\AGAP003611   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ010246
Orthologs in non-Dipteran Insects (EOG6P5J5P)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC412986 Y Apis mellifera Western honey bee  Amel\LOC552110 Y Apis mellifera Western honey bee  Amel\FAR1 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG011569 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG032705 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG011574 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21313 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH16221 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH10002 Y Atta cephalotes Leafcutter ant  Acep\ACEP19749 Y Atta cephalotes Leafcutter ant  Acep\ACEP16703 Y Atta cephalotes Leafcutter ant  Acep\ACEP19759 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO17102 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO19189 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO19184 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO15899 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL12471 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14153 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL12464 Y Linepithema humile Argentine ant  Lhum\LH13325 Y Linepithema humile Argentine ant  Lhum\LH10411 Y Linepithema humile Argentine ant  Lhum\LH11788 Y Linepithema humile Argentine ant  Lhum\LH11790 Y Linepithema humile Argentine ant  Lhum\LH11789 Y Linepithema humile Argentine ant  Lhum\LH16435 Y Linepithema humile Argentine ant  Lhum\LH13324 Y Linepithema humile Argentine ant  Lhum\LH16824 Y Linepithema humile Argentine ant  Lhum\LH16821 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB17473 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB24933 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB27271 Y Solenopsis invicta Red fire ant  Sinv\SINV15578 Y Solenopsis invicta Red fire ant  Sinv\SINV12536 Y Solenopsis invicta Red fire ant  Sinv\SINV17528 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI009674 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI003622 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI008817 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI28767 Y Bombyx mori Silkmoth  Bmor\BGIBMGA011148 Y Bombyx mori Silkmoth  Bmor\BGIBMGA011149 Y Bombyx mori Silkmoth  Bmor\BGIBMGA006569 Y Bombyx mori Silkmoth  Bmor\BGIBMGA011395 Y Bombyx mori Silkmoth  Bmor\BGIBMGA011217 Y Bombyx mori Silkmoth  Bmor\BGIBMGA000659 Y Pediculus humanus Human body louse  Phum\PHUM288740 Y Pediculus humanus Human body louse  Phum\PHUM288600 Y Pediculus humanus Human body louse  Phum\PHUM423990 Y Pediculus humanus Human body louse  Phum\PHUM561380 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15379 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15380 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15052 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15381 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15576 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15335 Y Tribolium castaneum Red flour beetle  Tcas\TC000107 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15341 Y
Orthologs in non-Insect Arthropods (EOG6JH9X6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\csrA Y Daphnia pulex Water flea  Dpux\JGI_V11_54498 Y Daphnia pulex Water flea  Dpux\COI Y Daphnia pulex Water flea  Dpux\JGI_V11_54566 Y Daphnia pulex Water flea  Dpux\JGI_V11_304841 Y Daphnia pulex Water flea  Dpux\JGI_V11_305905 Y Daphnia pulex Water flea  Dpux\JGI_V11_54466 Y Daphnia pulex Water flea  Dpux\JGI_V11_65872 Y Daphnia pulex Water flea  Dpux\JGI_V11_201098 Y Daphnia pulex Water flea  Dpux\Yp1 Y Daphnia pulex Water flea  Dpux\M Y Daphnia pulex Water flea  Dpux\cox1 Y Daphnia pulex Water flea  Dpux\JGI_V11_213553 Y Daphnia pulex Water flea  Dpux\matK Y Daphnia pulex Water flea  Dpux\JGI_V11_233376 Y Daphnia pulex Water flea  Dpux\psbA Y Ixodes scapularis Deer tick  Isca\ISCW003967 Y Ixodes scapularis Deer tick  Isca\ISCW009857 Y Ixodes scapularis Deer tick  Isca\ISCW021433 Y Ixodes scapularis Deer tick  Isca\ISCW017498 Y Ixodes scapularis Deer tick  Isca\ISCW021430 Y Ixodes scapularis Deer tick  Isca\ISCW017626 Y
Orthologs in non-Arthropod Metazoa (EOG6PCPKS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\Y71H10A.2 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_011985gn Y Danio rerio Zebrafish  Drer\si:dkey-97m3.1 Y Danio rerio Zebrafish  Drer\far1 Y Xenopus tropicalis Western clawed frog  Xtro\far1 Y Gallus gallus Domestic chicken  Ggal\FAR1 Y Gallus gallus Domestic chicken  Ggal\FAR2 Y Mus musculus House mouse  Mmus\Far2 Y Mus musculus House mouse  Mmus\Far1 Y Rattus norvegicus Norway rat  Rnor\Far1 Y Rattus norvegicus Norway rat  Rnor\Far2 Y Homo sapiens Human  Hsap\FAR1 Y
Human Orthologs (1)
Gene OMIM HGNC Hsap\FAR1
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD24908 Drosophila sechellia Dsec\GM11778 Drosophila erecta Dere\GG19877 Drosophila yakuba Dyak\GE11401 Drosophila ananassae Dana\GF11526 Drosophila pseudoobscura pseudoobscura Dpse\GA24528 Drosophila willistoni Dwil\GK20732 Drosophila virilis Dvir\GJ22269 Drosophila mojavensis Dmoj\GI19136 Drosophila grimshawi Dgri\GH22050
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	27882 w1118; Mi{ET1}CG30427MB12237
Harvard	- PBac{PB}CG30427c01123 - PBac{WH}CG30427f00041 - PBac{WH}CG30427f05660
VDRC	v102330 P{KK111350}VIE-260B v7423 w1118 P{GD2222}v7423
Genomic Clones ( 1 )
	BACR08I14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 51 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD36843 LP07070 RE01655 RH64234
Other clones	DPiM_LD36843 FI09309 FI20130
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH21625 LD40386 RE12791 RE14848 RE21341 RE21633 RE34774 RE37230 RE37928 RE38465 RE38565 RE38711 RE49768 RE66003 RE66006 RE66088 RH04080 RH04103 RH43839
Other clones	38948 51295 58814 60137 66274 102651 214505.67 214531.65 275205 CK01.36B.B1 CK01.59A.F1 Dmel_dig_012861_0691_0355 EK034629 EK039443 EK047816 EK066051 EK095508 EK151860 EK168357 EK182524 EK225948 EK302711 EP01339 EP03255 MB6-CG30427-RD
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0043792 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37986
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: BEST:LD36843 CG30427 (FlyBase, 1996-) Source for merge of: CG2858 CG18680 (FlyBase, 1996-) Source for merge of: CG18680 CG2858 (FlyBase Genome Annotators, 2002-2003)
Additional comments	Annotations CG18680 and CG2858 merged as CG30427 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003) Source for merge of CG2858 CG18680 was a shared cDNA (date:010720). (FlyBase, 1996-) Source for merge of BEST:LD36843 CG30427 was a shared cDNA (date:030206). (FlyBase, 1996-)
Other Comments
	S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells. (Stroschein-Stevenson et al., 2006)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_138136 NM_166697 NM_166698 NM_166699 NM_001169827 NM_001169828 NM_001259583 RefSeq (Proteins) • NP_611980 NP_726498 NP_726499 NP_726500 NP_001163298 NP_001163299 NP_001246512 DDBJ / EMBL / GenBank • AAF47294 AAF47295 AAK93298 AAM70799 AAM70800 AAX33483 ACZ94570 ACZ94571 AFH08265 AI456727 AW943358 AY051874 BI162293 BI162294 BT021335 CZ466916 CZ466917 CZ482527 CZ488277 Entrez Gene - A searchable database of RefSeq genes. • 37986 UniProtKB/TrEMBL • Q0E8W1 Q5BI89 Q8MMC6 Q9W0Y5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Male sterility, NAD-binding (IPR013120) NAD(P)-binding domain (IPR016040) Fatty acyl-CoA reductase (IPR026055) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD36843
Linkouts
	BioGRID - A database of protein and genetic interactions • 63554 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0043792 DroID - A comprehensive database of gene and protein interactions. • FBgn0043792 DRSC - Results from RNAi screens. • FBgn0043792 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0043792 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30427-RA;CG30427-RB;CG30427-RC FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0043792 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37986 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37986 modMine - Data generated by the modENCODE project. • FBgn0043792
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	BEST:LD36843 (Zou et al., 2000, ) CG2858 (Arbeitman et al., 2004, ) CG18680   CG30427 (Stroschein-Stevenson et al., 2006, Goldman and Arbeitman, 2007, Lebo et al., 2009, Ye et al., 2009, Keleman et al., 2009.8.5, Malko et al., 2006, Paik et al., 2012)
Name Synonym
Secondary FlyBase IDs
	FBgn0035081 FBgn0040667 FBgn0050427
References ( 24 )
Generate a list of	All references relating to this gene ( 24 )
List References by type	Research paper  ( 9 ) Supplementary material  ( 3 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 3 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 1 )
	Paik et al., 2012, Mech. Ageing Dev. 133(5): 234--245 Misexpression screen delineates novel genes controlling Drosophila lifespan. [FBrf0218389] Show all research papers ...