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Gene Dmel\vir-1

General Information
Symbol	Dmel\vir-1	Species	D. melanogaster
Name	virus-induced RNA 1	Annotation symbol	CG31764
Feature type	protein_coding_gene	FlyBase ID	FBgn0043841
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	33E3-33E4	Sequence location	2L:12,403,270..12,423,439 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene virus-induced RNA 1 is referred to in FlyBase by the symbol Dmel\vir-1 (CG31764, FBgn0043841). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: defense response to virus. 7 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system, adult crop, larval trachea, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, larval/adult hindgut, adult heart, adult salivary gland, inseminated spermatheca, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1625012_s_at completely aligns to an exonic region of only a subset of 3 of the 4 FlyBase-annotated transcript isoforms of vir-1. Gene sequence location is 2L:12403270..12423439.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03	Alleles vir-1[MI05999]
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 33E3-33E4   Limits computationally determined from genome sequence between P{PZ}Rab608323 and P{EP}ElfEP476&P{EP}bunEP488
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\vir-1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model includes transcripts encoding non-overlapping portions of the full CDS. Gene model reviewed during 5.47 Annotated transcripts do not represent all supported alternative splices within 5' UTR. Low-frequency RNA-Seq exon junction(s) not annotated. Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) vir-1-RA FBtr0080390  NM_165010   1765   431 vir-1-RB FBtr0080389  NM_165011   1849   431 vir-1-RC FBtr0080391  NM_205966   1048   234 vir-1-RD FBtr0100125  NM_001038812   905   155 vir-1-RE FBtr0305263  NM_001259074   953   155 vir-1-RG FBtr0334761  NM_001273483   1814   423 vir-1-RH FBtr0334762  NM_001259075   1121   234
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein vir-1-PA   FBpp0079971   48.6   431   3.93     NP_723746   AAF53185 vir-1-PB   FBpp0079970   48.6   431   3.93     NP_723747   AAF53184 vir-1-PC   FBpp0079972   25.7   234   4.25     NP_995688   AAS64683 vir-1-PD   FBpp0099471   18.3   155   3.75     NP_001033901   ABC65895 vir-1-PE   FBpp0293787   18.3   155   3.75     NP_001246003   AFH03677 vir-1-PG   FBpp0306802   47.6   423   3.92     NP_001260412   AGB92947 vir-1-PH   FBpp0306803   25.7   234   4.25     NP_001246004   AFH03678
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF53184   AE014134 AAF53185   AE014134 AAS64683   AE014134 ABC65895   AE014134 AFH03677   AE014134 AFH03678   AE014134 AGB92947   AI062863   AI063546   AI064602   AI107300   AI107369   AI107899   AI108818   AI109320   AI109362   AI109662   AI113915   AI114292   AI135935   AI238007   AI238381   AI238492   AI257521   AI260706   AI260782   AI292644   AI297492   AI297712   AI386856   AI386890   AI388001   AI388164   AI389250   AI389938   AI404102   AI404417   AI404916   AI404952   AI405368   AI405802   AI513723   AI514098   AI517668   AW940079   AY071148 AAL48770   AY094667 AAM11020   BF496687   BG632510   BG633396   BG635804   BI212852   BI227609   BI353901   BI356725   BI357798   BI364823   BI364867   BI486525   BI563622   BI563862   BI564973   BI566986   BI567009   BI567589   BI569856   BI571462   BI574117   BI574578   BI575168   BI575918   BI576253   BI576432   BI576683   BI581113   BI581114   BI583056   BI583250   BI584419   BI584563   BI585652   BI586824   BI588311   BI589252   BI590028   BI590611   BI590695   BI591992   BI604513   BI604749   BI605437   BI605488   BI608891   BI610090   BI610143   BI610250   BI612756   BI612757   BI615243   BI615505   BI618185   BI621327   BI625816   BI634692   BP550543   BP550544   BT044312   CA804785   CK658526   CL526039   CO153394   CO153841   CO153908   CO154587   CO154606   CO154668   CO154781   CO155591   CO155803   CO156044   CO156104   CO156117   CO156448   CO156674   CO156690   CO157047   CO182253   CO185788   CO188232   CO190661   CO191129   CO192775   CO196426   CO268596   CO278453   CO278740   CO285510   CO288062   CO311862   CO320953   CO326294   CO335450   CO335464   CO336238   CO336378   CO336614   CO336668   CO337121   CO337572   CO337614   CZ478653   DQ143902 AAZ73098   EC062636   EC067294   EC070862   EC072642   EC075521   EC196165   EC213804   EC215302   EC229036   EC242780   EC261190   EC261517   EC261836   EC261929   EC261937   EC262170   EC262208   EC263718   EC263914   EC263953   EC264773   EC265220   EC265592   EC265881   EC266131   EC266348   EC266698   EC267134   EC267572   EC267774   EC267794   EL872075   EL884797   ES690822   EV583349   EV585699   EV589433   EV599376
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q3YBY4 Q8SXD5 Q0E8R1 Q8SZ36
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 11 -- 12   midline primordium   (Fisher et al., 2012) posterior spiracle primordium   (Fisher et al., 2012) Comment:reported as posterior spiracle specific anlage embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) embryonic central brain   (Fisher et al., 2012) embryonic/larval nervous system   (Fisher et al., 2012) embryonic/larval oenocyte   (Fisher et al., 2012) embryonic/larval posterior spiracle   (Fisher et al., 2012) midline ventral glial cell   (Fisher et al., 2012) ventral midline   (Fisher et al., 2012) ventral midline neuron   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system, adult crop, larval trachea, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, larval/adult hindgut, adult heart, adult salivary gland, inseminated spermatheca, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    497.125 Larval Midgut    63.8 Larval Hindgut    327.1 Larval Malpighian Tubules    14.1 Larval Fat Body    37 Larval Salivary Gland    42.4 Larval Trachea    1684.9 Larval Carcass    611.975 Adult Head    440.8 Adult Eye    255.775 Adult Brain    693.9 Adult Thoracic-Abdominal Ganglion    1363 Adult Crop    998.9 Adult Midgut    98.9 Adult Hindgut    431.9 Adult Malpighian Tubules    16.7 Adult Fat Body    35.6 Adult Salivary Gland    104.5 Adult Heart    262.65 Adult VirginFemale Spermatheca    57.1 Adult InseminatedFemale Spermatheca    333.4 Adult Ovary    8.6 Adult Testis    36.7 Adult Male Accessory Gland    41.4 Adult Carcass    257.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    497.125 Larval Midgut    63.8 Larval Hindgut    327.1 Larval Malpighian Tubules    14.1 Larval Fat Body    37 Larval Salivary Gland    42.4 Larval Trachea  (1684.9) Larval Carcass  (611.975) Adult Head    440.8 Adult Eye    255.775 Adult Brain  (693.9) Adult Thoracic-Abdominal Ganglion  (1363) Adult Crop  (998.9) Adult Midgut    98.9 Adult Hindgut    431.9 Adult Malpighian Tubules    16.7 Adult Fat Body    35.6 Adult Salivary Gland    104.5 Adult Heart    262.65 Adult VirginFemale Spermatheca    57.1 Adult InseminatedFemale Spermatheca    333.4 Adult Ovary    8.6 Adult Testis    36.7 Adult Male Accessory Gland    41.4 Adult Carcass    257.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    497.125 Larval Midgut    63.8 Larval Hindgut    327.1 Larval Malpighian Tubules    14.1 Larval Fat Body    37 Larval Salivary Gland    42.4 Larval Trachea  (1684.9) Larval Carcass    611.975 Adult Head    440.8 Adult Eye    255.775 Adult Brain    693.9 Adult Thoracic-Abdominal Ganglion  (1363) Adult Crop    998.9 Adult Midgut    98.9 Adult Hindgut    431.9 Adult Malpighian Tubules    16.7 Adult Fat Body    35.6 Adult Salivary Gland    104.5 Adult Heart    262.65 Adult VirginFemale Spermatheca    57.1 Adult InseminatedFemale Spermatheca    333.4 Adult Ovary    8.6 Adult Testis    36.7 Adult Male Accessory Gland    41.4 Adult Carcass    257.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    497.125 Larval Midgut    63.8 Larval Hindgut    327.1 Larval Malpighian Tubules    14.1 Larval Fat Body    37 Larval Salivary Gland    42.4 Larval Trachea    1684.9 Larval Carcass    611.975 Adult Head    440.8 Adult Eye    255.775 Adult Brain    693.9 Adult Thoracic-Abdominal Ganglion    1363 Adult Crop    998.9 Adult Midgut    98.9 Adult Hindgut    431.9 Adult Malpighian Tubules    16.7 Adult Fat Body    35.6 Adult Salivary Gland    104.5 Adult Heart    262.65 Adult VirginFemale Spermatheca    57.1 Adult InseminatedFemale Spermatheca    333.4 Adult Ovary    8.6 Adult Testis    36.7 Adult Male Accessory Gland    41.4 Adult Carcass    257.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    497.125 Larval Midgut    63.8 Larval Hindgut    327.1 Larval Malpighian Tubules    14.1 Larval Fat Body    37 Larval Salivary Gland    42.4 Larval Trachea    1684.9 Larval Carcass    611.975 Adult Head    440.8 Adult Eye    255.775 Adult Brain    693.9 Adult Thoracic-Abdominal Ganglion    1363 Adult Crop    998.9 Adult Midgut    98.9 Adult Hindgut    431.9 Adult Malpighian Tubules    16.7 Adult Fat Body    35.6 Adult Salivary Gland    104.5 Adult Heart    262.65 Adult VirginFemale Spermatheca    57.1 Adult InseminatedFemale Spermatheca    333.4 Adult Ovary    8.6 Adult Testis    36.7 Adult Male Accessory Gland    41.4 Adult Carcass    257.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    497.125 Larval Midgut    63.8 Larval Hindgut    327.1 Larval Malpighian Tubules    14.1 Larval Fat Body    37 Larval Salivary Gland    42.4 Larval Trachea  (1684.9) Larval Carcass  611.975 Adult Head    440.8 Adult Eye    255.775 Adult Brain  693.9 Adult Thoracic-Abdominal Ganglion  (1363) Adult Crop  (998.9) Adult Midgut    98.9 Adult Hindgut    431.9 Adult Malpighian Tubules    16.7 Adult Fat Body    35.6 Adult Salivary Gland    104.5 Adult Heart    262.65 Adult VirginFemale Spermatheca    57.1 Adult InseminatedFemale Spermatheca    333.4 Adult Ovary    8.6 Adult Testis    36.7 Adult Male Accessory Gland    41.4 Adult Carcass    257.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    497.125 Larval Midgut    63.8 Larval Hindgut    327.1 Larval Malpighian Tubules    14.1 Larval Fat Body    37 Larval Salivary Gland    42.4 Larval Trachea  1684.9 Larval Carcass    611.975 Adult Head    440.8 Adult Eye    255.775 Adult Brain    693.9 Adult Thoracic-Abdominal Ganglion  1363 Adult Crop    998.9 Adult Midgut    98.9 Adult Hindgut    431.9 Adult Malpighian Tubules    16.7 Adult Fat Body    35.6 Adult Salivary Gland    104.5 Adult Heart    262.65 Adult VirginFemale Spermatheca    57.1 Adult InseminatedFemale Spermatheca    333.4 Adult Ovary    8.6 Adult Testis    36.7 Adult Male Accessory Gland    41.4 Adult Carcass    257.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    497.125 Larval Midgut    63.8 Larval Hindgut    327.1 Larval Malpighian Tubules    14.1 Larval Fat Body    37 Larval Salivary Gland    42.4 Larval Trachea    1684.9 Larval Carcass    611.975 Adult Head    440.8 Adult Eye    255.775 Adult Brain    693.9 Adult Thoracic-Abdominal Ganglion    1363 Adult Crop    998.9 Adult Midgut    98.9 Adult Hindgut    431.9 Adult Malpighian Tubules    16.7 Adult Fat Body    35.6 Adult Salivary Gland    104.5 Adult Heart    262.65 Adult VirginFemale Spermatheca    57.1 Adult InseminatedFemale Spermatheca    333.4 Adult Ovary    8.6 Adult Testis    36.7 Adult Male Accessory Gland    41.4 Adult Carcass    257.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    440.8   NA  Eye    255.775   NA  Brain    693.9   497.125  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1363   NA  Crop    998.9   63.8  Midgut    98.9   327.1  Hindgut    431.9   no informative data  Malpighian Tubules    no informative data   no informative data  Fat Body    35.6   42.4  Salivary Gland    104.5   NA  Heart    262.65   1684.9  Trachea    NA   NA  VirginFemale Spermatheca    57.1   NA  InseminatedFemale Spermatheca    333.4   NA  Ovary    8.6   NA  Testis    36.7   NA  Male Accessory Gland    41.4   611.975  Carcass    257.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    43 central nervous system, pupae P8    79 head, virgin 1-day female    79 head, virgin 4-day female    107 head, virgin 20-day female    198 head, mated 1-day female    87 head, mated 4-day female    128 head, mated 20-day female    159 head, mated 1-day male    119 head, mated 4-day male    178 head, mated 20-day male    303 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    31 digestive system, larvae L3 wandering    24 digestive system, 1-day adult    42 digestive system, 4-day adult    35 digestive system, 20-day adult    40 fat body, larvae L3 wandering    143 fat body, white prepupae    253 fat body, pupae P8    310 carcass, larvae L3 wandering    92 carcass, 1-day adult    135 carcass, 4-day adult    151 carcass, 20-day adult    249 ovary, virgin 4-day female    8 ovary, mated 4-day female    6 testis, mated 4-day male    65 accessory gland, mated 4-day male    96 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3  (43) central nervous system, pupae P8  (79) head, virgin 1-day female  (79) head, virgin 4-day female  (107) head, virgin 20-day female  (198) head, mated 1-day female  (87) head, mated 4-day female  (128) head, mated 20-day female  (159) head, mated 1-day male  (119) head, mated 4-day male  (178) head, mated 20-day male  (303) salivary gland, larvae L3 wandering    10 salivary gland, white prepupae  (31) digestive system, larvae L3 wandering    24 digestive system, 1-day adult  (42) digestive system, 4-day adult  (35) digestive system, 20-day adult  (40) fat body, larvae L3 wandering  (143) fat body, white prepupae  (253) fat body, pupae P8  (310) carcass, larvae L3 wandering  (92) carcass, 1-day adult  (135) carcass, 4-day adult  (151) carcass, 20-day adult  (249) ovary, virgin 4-day female    8 ovary, mated 4-day female    6 testis, mated 4-day male  (65) accessory gland, mated 4-day male  (96) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    43 central nervous system, pupae P8    79 head, virgin 1-day female    79 head, virgin 4-day female  107 head, virgin 20-day female  (198) head, mated 1-day female    87 head, mated 4-day female  (128) head, mated 20-day female  (159) head, mated 1-day male  (119) head, mated 4-day male  (178) head, mated 20-day male  (303) salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    31 digestive system, larvae L3 wandering    24 digestive system, 1-day adult    42 digestive system, 4-day adult    35 digestive system, 20-day adult    40 fat body, larvae L3 wandering  (143) fat body, white prepupae  (253) fat body, pupae P8  (310) carcass, larvae L3 wandering    92 carcass, 1-day adult  (135) carcass, 4-day adult  (151) carcass, 20-day adult  (249) ovary, virgin 4-day female    8 ovary, mated 4-day female    6 testis, mated 4-day male    65 accessory gland, mated 4-day male    96 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    43 central nervous system, pupae P8    79 head, virgin 1-day female    79 head, virgin 4-day female    107 head, virgin 20-day female    198 head, mated 1-day female    87 head, mated 4-day female    128 head, mated 20-day female    159 head, mated 1-day male    119 head, mated 4-day male    178 head, mated 20-day male    303 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    31 digestive system, larvae L3 wandering    24 digestive system, 1-day adult    42 digestive system, 4-day adult    35 digestive system, 20-day adult    40 fat body, larvae L3 wandering    143 fat body, white prepupae    253 fat body, pupae P8    310 carcass, larvae L3 wandering    92 carcass, 1-day adult    135 carcass, 4-day adult    151 carcass, 20-day adult    249 ovary, virgin 4-day female    8 ovary, mated 4-day female    6 testis, mated 4-day male    65 accessory gland, mated 4-day male    96 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    43 central nervous system, pupae P8    79 head, virgin 1-day female    79 head, virgin 4-day female    107 head, virgin 20-day female    198 head, mated 1-day female    87 head, mated 4-day female    128 head, mated 20-day female    159 head, mated 1-day male    119 head, mated 4-day male    178 head, mated 20-day male    303 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    31 digestive system, larvae L3 wandering    24 digestive system, 1-day adult    42 digestive system, 4-day adult    35 digestive system, 20-day adult    40 fat body, larvae L3 wandering    143 fat body, white prepupae    253 fat body, pupae P8    310 carcass, larvae L3 wandering    92 carcass, 1-day adult    135 carcass, 4-day adult    151 carcass, 20-day adult    249 ovary, virgin 4-day female    8 ovary, mated 4-day female    6 testis, mated 4-day male    65 accessory gland, mated 4-day male    96 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3  (43) central nervous system, pupae P8  (79) head, virgin 1-day female  (79) head, virgin 4-day female  (107) head, virgin 20-day female  (198) head, mated 1-day female  (87) head, mated 4-day female  (128) head, mated 20-day female  (159) head, mated 1-day male  (119) head, mated 4-day male  (178) head, mated 20-day male  (303) salivary gland, larvae L3 wandering    10 salivary gland, white prepupae  31 digestive system, larvae L3 wandering    24 digestive system, 1-day adult  (42) digestive system, 4-day adult  (35) digestive system, 20-day adult  (40) fat body, larvae L3 wandering  (143) fat body, white prepupae  (253) fat body, pupae P8  (310) carcass, larvae L3 wandering  (92) carcass, 1-day adult  (135) carcass, 4-day adult  (151) carcass, 20-day adult  (249) ovary, virgin 4-day female    8 ovary, mated 4-day female    6 testis, mated 4-day male  (65) accessory gland, mated 4-day male  (96) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    43 central nervous system, pupae P8    79 head, virgin 1-day female    79 head, virgin 4-day female  107 head, virgin 20-day female  (198) head, mated 1-day female    87 head, mated 4-day female  128 head, mated 20-day female  (159) head, mated 1-day male  119 head, mated 4-day male  (178) head, mated 20-day male  (303) salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    31 digestive system, larvae L3 wandering    24 digestive system, 1-day adult    42 digestive system, 4-day adult    35 digestive system, 20-day adult    40 fat body, larvae L3 wandering  143 fat body, white prepupae  (253) fat body, pupae P8  (310) carcass, larvae L3 wandering    92 carcass, 1-day adult  135 carcass, 4-day adult  (151) carcass, 20-day adult  (249) ovary, virgin 4-day female    8 ovary, mated 4-day female    6 testis, mated 4-day male    65 accessory gland, mated 4-day male    96 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    43 central nervous system, pupae P8    79 head, virgin 1-day female    79 head, virgin 4-day female    107 head, virgin 20-day female    198 head, mated 1-day female    87 head, mated 4-day female    128 head, mated 20-day female    159 head, mated 1-day male    119 head, mated 4-day male    178 head, mated 20-day male    303 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    31 digestive system, larvae L3 wandering    24 digestive system, 1-day adult    42 digestive system, 4-day adult    35 digestive system, 20-day adult    40 fat body, larvae L3 wandering    143 fat body, white prepupae    253 fat body, pupae P8    310 carcass, larvae L3 wandering    92 carcass, 1-day adult    135 carcass, 4-day adult    151 carcass, 20-day adult    249 ovary, virgin 4-day female    8 ovary, mated 4-day female    6 testis, mated 4-day male    65 accessory gland, mated 4-day male    96 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    3 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    11 embryo 12-14hr    12 embryo 14-16hr    8 embryo 16-18hr    13 embryo 18-20hr    31 embryo 20-22hr    36 embryo 22-24hr    42 larva L1    28 larva L2    23 larva L3 12hr old    56 larva L3 puffstage 1-2    117 larva L3 puffstage 3-6    151 larva L3 puffstage 7-9    152 white prepupae new    180 white prepupae 12hr    370 white prepupae 24hr    218 pupae 2d postWPP    144 pupae 3d postWPP    99 pupae 4d postWPP    140 adult male 01day    159 adult male 05day    215 adult male 30day    247 adult female 01day    95 adult female 05day    83 adult female 30day    112 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    3 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    11 embryo 12-14hr    12 embryo 14-16hr    8 embryo 16-18hr    13 embryo 18-20hr  (31) embryo 20-22hr  (36) embryo 22-24hr  (42) larva L1  (28) larva L2    23 larva L3 12hr old  (56) larva L3 puffstage 1-2  (117) larva L3 puffstage 3-6  (151) larva L3 puffstage 7-9  (152) white prepupae new  (180) white prepupae 12hr  (370) white prepupae 24hr  (218) pupae 2d postWPP  (144) pupae 3d postWPP  (99) pupae 4d postWPP  (140) adult male 01day  (159) adult male 05day  (215) adult male 30day  (247) adult female 01day  (95) adult female 05day  (83) adult female 30day  (112) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    3 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    11 embryo 12-14hr    12 embryo 14-16hr    8 embryo 16-18hr    13 embryo 18-20hr    31 embryo 20-22hr    36 embryo 22-24hr    42 larva L1    28 larva L2    23 larva L3 12hr old    56 larva L3 puffstage 1-2  (117) larva L3 puffstage 3-6  (151) larva L3 puffstage 7-9  (152) white prepupae new  (180) white prepupae 12hr  (370) white prepupae 24hr  (218) pupae 2d postWPP  (144) pupae 3d postWPP    99 pupae 4d postWPP  (140) adult male 01day  (159) adult male 05day  (215) adult male 30day  (247) adult female 01day    95 adult female 05day    83 adult female 30day  (112) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    3 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    11 embryo 12-14hr    12 embryo 14-16hr    8 embryo 16-18hr    13 embryo 18-20hr    31 embryo 20-22hr    36 embryo 22-24hr    42 larva L1    28 larva L2    23 larva L3 12hr old    56 larva L3 puffstage 1-2    117 larva L3 puffstage 3-6    151 larva L3 puffstage 7-9    152 white prepupae new    180 white prepupae 12hr    370 white prepupae 24hr    218 pupae 2d postWPP    144 pupae 3d postWPP    99 pupae 4d postWPP    140 adult male 01day    159 adult male 05day    215 adult male 30day    247 adult female 01day    95 adult female 05day    83 adult female 30day    112 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    3 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    11 embryo 12-14hr    12 embryo 14-16hr    8 embryo 16-18hr    13 embryo 18-20hr    31 embryo 20-22hr    36 embryo 22-24hr    42 larva L1    28 larva L2    23 larva L3 12hr old    56 larva L3 puffstage 1-2    117 larva L3 puffstage 3-6    151 larva L3 puffstage 7-9    152 white prepupae new    180 white prepupae 12hr    370 white prepupae 24hr    218 pupae 2d postWPP    144 pupae 3d postWPP    99 pupae 4d postWPP    140 adult male 01day    159 adult male 05day    215 adult male 30day    247 adult female 01day    95 adult female 05day    83 adult female 30day    112 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    3 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    11 embryo 12-14hr    12 embryo 14-16hr    8 embryo 16-18hr    13 embryo 18-20hr  31 embryo 20-22hr  (36) embryo 22-24hr  (42) larva L1  28 larva L2    23 larva L3 12hr old  (56) larva L3 puffstage 1-2  (117) larva L3 puffstage 3-6  (151) larva L3 puffstage 7-9  (152) white prepupae new  (180) white prepupae 12hr  (370) white prepupae 24hr  (218) pupae 2d postWPP  (144) pupae 3d postWPP  (99) pupae 4d postWPP  (140) adult male 01day  (159) adult male 05day  (215) adult male 30day  (247) adult female 01day  (95) adult female 05day  (83) adult female 30day  (112) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    3 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    11 embryo 12-14hr    12 embryo 14-16hr    8 embryo 16-18hr    13 embryo 18-20hr    31 embryo 20-22hr    36 embryo 22-24hr    42 larva L1    28 larva L2    23 larva L3 12hr old    56 larva L3 puffstage 1-2  117 larva L3 puffstage 3-6  (151) larva L3 puffstage 7-9  (152) white prepupae new  (180) white prepupae 12hr  (370) white prepupae 24hr  (218) pupae 2d postWPP  (144) pupae 3d postWPP    99 pupae 4d postWPP  140 adult male 01day  (159) adult male 05day  (215) adult male 30day  (247) adult female 01day    95 adult female 05day    83 adult female 30day  112 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    3 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    11 embryo 12-14hr    12 embryo 14-16hr    8 embryo 16-18hr    13 embryo 18-20hr    31 embryo 20-22hr    36 embryo 22-24hr    42 larva L1    28 larva L2    23 larva L3 12hr old    56 larva L3 puffstage 1-2    117 larva L3 puffstage 3-6    151 larva L3 puffstage 7-9    152 white prepupae new    180 white prepupae 12hr    370 white prepupae 24hr    218 pupae 2d postWPP    144 pupae 3d postWPP    99 pupae 4d postWPP    140 adult male 01day    159 adult male 05day    215 adult male 30day    247 adult female 01day    95 adult female 05day    83 adult female 30day    112 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    167 Schneider line 2 Sg4    146 embryonic 1182-4H    80 embryonic GM2    145 embryonic Kc167    87 embryonic S1    54 embryonic S3    5 leg disc CME L1    158 wing disc CME-W2    146 wing disc ML-DmD8    140 wing disc ML-DmD9    114 wing disc ML-DmD16-c3    113 wing disc ML-DmD21    93 wing disc ML-DmD32    403 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    73 antennal disc ML-DmD20-c5    327 mixed discs ML-DmD4-c1    54 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    104 tumorous blood cells mbn2    563 ovary fGS/OSS    10 ovary OSC    14 ovary OSS    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (167) Schneider line 2 Sg4  (146) embryonic 1182-4H  (80) embryonic GM2  (145) embryonic Kc167  (87) embryonic S1  (54) embryonic S3    5 leg disc CME L1  (158) wing disc CME-W2  (146) wing disc ML-DmD8  (140) wing disc ML-DmD9  (114) wing disc ML-DmD16-c3  (113) wing disc ML-DmD21  (93) wing disc ML-DmD32  (403) haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11  (73) antennal disc ML-DmD20-c5  (327) mixed discs ML-DmD4-c1  (54) CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2  (104) tumorous blood cells mbn2  (563) ovary fGS/OSS    10 ovary OSC    14 ovary OSS    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (167) Schneider line 2 Sg4  (146) embryonic 1182-4H    80 embryonic GM2  (145) embryonic Kc167    87 embryonic S1    54 embryonic S3    5 leg disc CME L1  (158) wing disc CME-W2  (146) wing disc ML-DmD8  (140) wing disc ML-DmD9  (114) wing disc ML-DmD16-c3  (113) wing disc ML-DmD21    93 wing disc ML-DmD32  (403) haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    73 antennal disc ML-DmD20-c5  (327) mixed discs ML-DmD4-c1    54 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2  104 tumorous blood cells mbn2  (563) ovary fGS/OSS    10 ovary OSC    14 ovary OSS    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    167 Schneider line 2 Sg4    146 embryonic 1182-4H    80 embryonic GM2    145 embryonic Kc167    87 embryonic S1    54 embryonic S3    5 leg disc CME L1    158 wing disc CME-W2    146 wing disc ML-DmD8    140 wing disc ML-DmD9    114 wing disc ML-DmD16-c3    113 wing disc ML-DmD21    93 wing disc ML-DmD32    403 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    73 antennal disc ML-DmD20-c5    327 mixed discs ML-DmD4-c1    54 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    104 tumorous blood cells mbn2    563 ovary fGS/OSS    10 ovary OSC    14 ovary OSS    25 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    167 Schneider line 2 Sg4    146 embryonic 1182-4H    80 embryonic GM2    145 embryonic Kc167    87 embryonic S1    54 embryonic S3    5 leg disc CME L1    158 wing disc CME-W2    146 wing disc ML-DmD8    140 wing disc ML-DmD9    114 wing disc ML-DmD16-c3    113 wing disc ML-DmD21    93 wing disc ML-DmD32    403 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    73 antennal disc ML-DmD20-c5    327 mixed discs ML-DmD4-c1    54 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    104 tumorous blood cells mbn2    563 ovary fGS/OSS    10 ovary OSC    14 ovary OSS    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (167) Schneider line 2 Sg4  (146) embryonic 1182-4H  (80) embryonic GM2  (145) embryonic Kc167  (87) embryonic S1  (54) embryonic S3    5 leg disc CME L1  (158) wing disc CME-W2  (146) wing disc ML-DmD8  (140) wing disc ML-DmD9  (114) wing disc ML-DmD16-c3  (113) wing disc ML-DmD21  (93) wing disc ML-DmD32  (403) haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11  (73) antennal disc ML-DmD20-c5  (327) mixed discs ML-DmD4-c1  (54) CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2  (104) tumorous blood cells mbn2  (563) ovary fGS/OSS    10 ovary OSC    14 ovary OSS    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (167) Schneider line 2 Sg4  (146) embryonic 1182-4H    80 embryonic GM2  (145) embryonic Kc167    87 embryonic S1    54 embryonic S3    5 leg disc CME L1  (158) wing disc CME-W2  (146) wing disc ML-DmD8  140 wing disc ML-DmD9  114 wing disc ML-DmD16-c3  113 wing disc ML-DmD21    93 wing disc ML-DmD32  (403) haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    73 antennal disc ML-DmD20-c5  (327) mixed discs ML-DmD4-c1    54 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2  104 tumorous blood cells mbn2  (563) ovary fGS/OSS    10 ovary OSC    14 ovary OSS    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    167 Schneider line 2 Sg4    146 embryonic 1182-4H    80 embryonic GM2    145 embryonic Kc167    87 embryonic S1    54 embryonic S3    5 leg disc CME L1    158 wing disc CME-W2    146 wing disc ML-DmD8    140 wing disc ML-DmD9    114 wing disc ML-DmD16-c3    113 wing disc ML-DmD21    93 wing disc ML-DmD32    403 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    73 antennal disc ML-DmD20-c5    327 mixed discs ML-DmD4-c1    54 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    104 tumorous blood cells mbn2    563 ovary fGS/OSS    10 ovary OSC    14 ovary OSS    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    60 cold shock, 4-day adult    35 heat shock, 4-day adult    63 Cadmium 50 mM 6 hrs, larvae L3    59 Cadmium 50 mM 12 hrs, larvae L3    86 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    88 Copper 0.5 mM 12 hrs, larvae L3    41 Copper 15 mM 48 hrs, 4-day adult    112 Zinc 5 mM 12 hrs, larvae L3    37 Zinc 4.5 mM 48 hrs, 4-day adult    141 Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    65 Caffeine 1.5 mg/ml 4 hrs, larvae L3    93 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    86 Caffeine 25 mg/ml 48 hrs, 4-day adult    40 Paraquat 5 mM 48 hrs, 4-day adult    71 Paraquat 10 mM 48 hrs, 4-day adult    144 Rotenone 2 μg 12 hrs, larvae L3    87 Rotenone 8 μg 12 hrs, larvae L3    73 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (60) cold shock, 4-day adult  (35) heat shock, 4-day adult  (63) Cadmium 50 mM 6 hrs, larvae L3  (59) Cadmium 50 mM 12 hrs, larvae L3  (86) Cadmium 50 mM 48 hrs, 4-day adult  (52) Cadmium 100 mM 48 hrs, 4-day adult  (88) Copper 0.5 mM 12 hrs, larvae L3  (41) Copper 15 mM 48 hrs, 4-day adult  (112) Zinc 5 mM 12 hrs, larvae L3  (37) Zinc 4.5 mM 48 hrs, 4-day adult  (141) Ethanol 2.5% 3 hrs, larvae L3  (71) Ethanol 5% 3 hrs, larvae L3  (84) Ethanol 10% 3 hrs, larvae L3  (65) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (93) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (86) Caffeine 25 mg/ml 48 hrs, 4-day adult  (40) Paraquat 5 mM 48 hrs, 4-day adult  (71) Paraquat 10 mM 48 hrs, 4-day adult  (144) Rotenone 2 μg 12 hrs, larvae L3  (87) Rotenone 8 μg 12 hrs, larvae L3  (73) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    60 cold shock, 4-day adult    35 heat shock, 4-day adult    63 Cadmium 50 mM 6 hrs, larvae L3    59 Cadmium 50 mM 12 hrs, larvae L3    86 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    88 Copper 0.5 mM 12 hrs, larvae L3    41 Copper 15 mM 48 hrs, 4-day adult  (112) Zinc 5 mM 12 hrs, larvae L3    37 Zinc 4.5 mM 48 hrs, 4-day adult  (141) Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    65 Caffeine 1.5 mg/ml 4 hrs, larvae L3    93 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    86 Caffeine 25 mg/ml 48 hrs, 4-day adult    40 Paraquat 5 mM 48 hrs, 4-day adult    71 Paraquat 10 mM 48 hrs, 4-day adult  (144) Rotenone 2 μg 12 hrs, larvae L3    87 Rotenone 8 μg 12 hrs, larvae L3    73 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    60 cold shock, 4-day adult    35 heat shock, 4-day adult    63 Cadmium 50 mM 6 hrs, larvae L3    59 Cadmium 50 mM 12 hrs, larvae L3    86 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    88 Copper 0.5 mM 12 hrs, larvae L3    41 Copper 15 mM 48 hrs, 4-day adult    112 Zinc 5 mM 12 hrs, larvae L3    37 Zinc 4.5 mM 48 hrs, 4-day adult    141 Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    65 Caffeine 1.5 mg/ml 4 hrs, larvae L3    93 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    86 Caffeine 25 mg/ml 48 hrs, 4-day adult    40 Paraquat 5 mM 48 hrs, 4-day adult    71 Paraquat 10 mM 48 hrs, 4-day adult    144 Rotenone 2 μg 12 hrs, larvae L3    87 Rotenone 8 μg 12 hrs, larvae L3    73 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    60 cold shock, 4-day adult    35 heat shock, 4-day adult    63 Cadmium 50 mM 6 hrs, larvae L3    59 Cadmium 50 mM 12 hrs, larvae L3    86 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    88 Copper 0.5 mM 12 hrs, larvae L3    41 Copper 15 mM 48 hrs, 4-day adult    112 Zinc 5 mM 12 hrs, larvae L3    37 Zinc 4.5 mM 48 hrs, 4-day adult    141 Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    65 Caffeine 1.5 mg/ml 4 hrs, larvae L3    93 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    86 Caffeine 25 mg/ml 48 hrs, 4-day adult    40 Paraquat 5 mM 48 hrs, 4-day adult    71 Paraquat 10 mM 48 hrs, 4-day adult    144 Rotenone 2 μg 12 hrs, larvae L3    87 Rotenone 8 μg 12 hrs, larvae L3    73 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (60) cold shock, 4-day adult  (35) heat shock, 4-day adult  (63) Cadmium 50 mM 6 hrs, larvae L3  (59) Cadmium 50 mM 12 hrs, larvae L3  (86) Cadmium 50 mM 48 hrs, 4-day adult  (52) Cadmium 100 mM 48 hrs, 4-day adult  (88) Copper 0.5 mM 12 hrs, larvae L3  (41) Copper 15 mM 48 hrs, 4-day adult  (112) Zinc 5 mM 12 hrs, larvae L3  (37) Zinc 4.5 mM 48 hrs, 4-day adult  (141) Ethanol 2.5% 3 hrs, larvae L3  (71) Ethanol 5% 3 hrs, larvae L3  (84) Ethanol 10% 3 hrs, larvae L3  (65) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (93) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (86) Caffeine 25 mg/ml 48 hrs, 4-day adult  (40) Paraquat 5 mM 48 hrs, 4-day adult  (71) Paraquat 10 mM 48 hrs, 4-day adult  (144) Rotenone 2 μg 12 hrs, larvae L3  (87) Rotenone 8 μg 12 hrs, larvae L3  (73) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    60 cold shock, 4-day adult    35 heat shock, 4-day adult    63 Cadmium 50 mM 6 hrs, larvae L3    59 Cadmium 50 mM 12 hrs, larvae L3    86 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    88 Copper 0.5 mM 12 hrs, larvae L3    41 Copper 15 mM 48 hrs, 4-day adult  112 Zinc 5 mM 12 hrs, larvae L3    37 Zinc 4.5 mM 48 hrs, 4-day adult  141 Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    65 Caffeine 1.5 mg/ml 4 hrs, larvae L3    93 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    86 Caffeine 25 mg/ml 48 hrs, 4-day adult    40 Paraquat 5 mM 48 hrs, 4-day adult    71 Paraquat 10 mM 48 hrs, 4-day adult  (144) Rotenone 2 μg 12 hrs, larvae L3    87 Rotenone 8 μg 12 hrs, larvae L3    73 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    60 cold shock, 4-day adult    35 heat shock, 4-day adult    63 Cadmium 50 mM 6 hrs, larvae L3    59 Cadmium 50 mM 12 hrs, larvae L3    86 Cadmium 50 mM 48 hrs, 4-day adult    52 Cadmium 100 mM 48 hrs, 4-day adult    88 Copper 0.5 mM 12 hrs, larvae L3    41 Copper 15 mM 48 hrs, 4-day adult    112 Zinc 5 mM 12 hrs, larvae L3    37 Zinc 4.5 mM 48 hrs, 4-day adult    141 Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    65 Caffeine 1.5 mg/ml 4 hrs, larvae L3    93 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    86 Caffeine 25 mg/ml 48 hrs, 4-day adult    40 Paraquat 5 mM 48 hrs, 4-day adult    71 Paraquat 10 mM 48 hrs, 4-day adult    144 Rotenone 2 μg 12 hrs, larvae L3    87 Rotenone 8 μg 12 hrs, larvae L3    73 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_04 mE1_20_mRNA_expression_cluster_15
External Data & Images
Linkouts	BDGP expression data • RE18101 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0043841 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG31764-RB FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for vir-1 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable vir-1EY08717 Sterility Allele fertile vir-1EY08717 Phenotype manifest in Allele
Classical Alleles ( 6 )
For All Classical Alleles Show
Allele of vir-1 Class Mutagen Stocks Known lesion vir-1EY08717 P-element activity 1 -- vir-1KG03668 1 -- vir-1MI00981 1 -- vir-1MI04501 1 -- vir-1e00810 piggyBac transposase 0 -- vir-1MI05999 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of vir-1 Class Mutagen Stocks Known lesion vir-1KK111921 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes vir-1GD4936 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4936} NA P{KK111921} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}vir-1EY08717 NA insertion of enhancer trap P{lacW}l(2)SH2154SH2154 No miscellaneous insertions Mi{MIC}vir-1MI00981 NA Mi{MIC}vir-1MI04501 NA Mi{MIC}vir-1MI05999 NA P{SUPor-P}vir-1KG03668 NA PBac{RB}vir-1e00810 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
defense response to virus inferred from expression pattern (Dostert et al., 2005)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
vir-1 - CG10641 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - CG32698 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - CG3735 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - CG5027 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - CG5642 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - CG8578 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - CG9581 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) vir-1 - Cg25C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - Cp1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - Hsc70-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - Int6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - Mtpα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - RpS21 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - eIF3-S8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - gish anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vir-1 - vkg anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions vir-1 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60700 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0043841 DroID - A comprehensive database of gene and protein interactions. • FBgn0043841 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34652
Orthologs
OrthoDB Orthologs (25) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6DNFQH Dipteran inclusive ortholog search EOG6M39JB Insect inclusive ortholog search EOG6H18S3 Arthropod inclusive ortholog search EOG68CZBN Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6DNFQH)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\vir-1     Drosophila simulans   Dsim\GD22123 Y   Drosophila sechellia   Dsec\GM26251 Y   Drosophila erecta   Dere\GG10265     Drosophila yakuba   Dyak\GE12315 Y   Drosophila ananassae   Dana\GF15675     Drosophila pseudoobscura pseudoobscura   Dpse\GA16459 Y   Drosophila persimilis   Dper\GL19505 Y   Drosophila willistoni   Dwil\GK14629 Y   Drosophila virilis   Dvir\GJ20102     Drosophila mojavensis   Dmoj\GI22225 Y   Drosophila grimshawi   Dgri\GH10136
Orthologs in non-Drosophila Dipterans (EOG6M39JB)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000718   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ012373
Orthologs in non-Dipteran Insects (EOG6H18S3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB40759   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007334   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH23165   Camponotus floridanus Florida carpenter ant  Cflo\CFLO12126   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15119   Linepithema humile Argentine ant  Lhum\LH15507   Pogonomyrmex barbatus Red harvester ant  Pbar\PB25516   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001152   Pediculus humanus Human body louse  Phum\PHUM153150   Tribolium castaneum Red flour beetle  Tcas\GLEAN_08024
Orthologs in non-Insect Arthropods (EOG68CZBN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_302249
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD22123 Drosophila sechellia Dsec\GM26251 Drosophila erecta Dere\GG10266 Drosophila yakuba Dyak\GE12315 Drosophila ananassae Dana\GF15676 Drosophila pseudoobscura pseudoobscura Dpse\GA16459 Drosophila persimilis Dper\GL19505 Drosophila willistoni Dwil\GK14629 Drosophila virilis Dvir\GJ20113 Drosophila mojavensis Dmoj\GI22225 Drosophila grimshawi Dgri\GH10137
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	34135 y1 w*; Mi{MIC}vir-1MI00981 40201 y1 w*; Mi{MIC}vir-1MI04501 17489 y1 w67c23; P{EPgy2}vir-1EY08717 13292 y1 w67c23; P{SUPor-P}vir-1KG03668
VDRC	v102534 P{KK111921}VIE-260B
Genomic Clones ( 1 )
	BACR48M09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 156 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH02216 RE18101
Other clones	DPiM_GH02216 FI07211
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT10579 GH03418 GH03888 GH04179 GH05066 GH05781 GH08110 GH08469 GH08525 GH08910 GH09792 GH10426 GH11089 GH13861 GH13964 GH14416 GH14543 GH15590 GH17207 GH17260 GH18726 GH18972 GH20377 GH21252 GH23696 GH24118 GH24776 GH24830 GH25347 GH25934 GH26157 GH26779 GH27156 GH28715 GM25526 LP04665 LP04755 LP05919 LP11801 LP12077 LP15494 RE24709 RE42926 RE44370 RE50011 RE50058 RE69967 RH02024 RH03577 RH04254 RH04351 RH06487 RH09571 RH13608 RH14964 RH15064 RH15335 RH21491 RH21618 RH21794 RH23618 RH23806 RH24732 RH25275 RH26933 RH28452 RH29476 RH31630 RH32294 RH32779 RH32990 RH33288 RH34290 RH34585 RH36807 RH36834 RH38118 RH38896 RH41710 RH41711 RH44828 RH45170 RH48772 RH52651 RH62577 RH66311 RH69910 RH70216 RH71042 RH71108 SD13301
Other clones	17934 56517 77984 104535 184465 291950 292093 295496 296473 296577 298189 CK01.10A.C2 Dmel_dig_012663_0618_0388 Dmel_dig_018017_0638_1027 Dmel_neb_002372_0875_0297 Dmel_neb_012274_0388_0480 EC22333 EC30167 EC34467 EK004308 EK012141 EK038542 EK049007 EK067641 EK092111 EK130116 EK131406 EK169138 EK227054 EK289164 EN01863 EN02928 EN03056 EN04421 EN04444 EN04553 EN04801 EN06363 EN06757 EN07241 EN07344 EN07358 EN08101 EN08551 EN08621 EN09832 EN10349 EN10504 EN12125 EN12420 EN12909 EN13009 EN13853 EN14828 EN14923 EP03609 ESG0115a.B21_H12 FGM207G04 IP04063 IP16035 RH01110
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0043841 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34652
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: vir-1 CG31764 (Imler, 2005.7.25)
Source for database merge of	Source for merge of: BEST:GH02216 CG31764 (FlyBase, 1996-) Source for merge of: CG15493 CG5453 (FlyBase Genome Annotators, 2002-2003)
Additional comments	Annotations CG15493 and CG5453 merged as CG31764 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003) Source for merge of BEST:GH02216 CG31764 was a shared cDNA (date:030206). (FlyBase, 1996-)
Other Comments
	Nonsense-mediated mRNA decay (NMD) down-regulates a distinct splice isoform(s) of this gene. (Hansen et al., 2009)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_165010 NM_165011 NM_205966 NM_001038812 NM_001259074 NM_001259075 NM_001273483 RefSeq (Proteins) • NP_723746 NP_723747 NP_995688 NP_001033901 NP_001246003 NP_001246004 NP_001260412 DDBJ / EMBL / GenBank • AAF53184 AAF53184.2 AAF53185 AAF53185.2 AAL48770 AAM11020 AAS64683 AAS64683.1 AAZ73098 ABC65895 AFH03677 AFH03678 AGB92947 AI062863 AW940079 AY071148 AY094667 BI212852 CL526039 CZ478653 DQ143902 Entrez Gene - A searchable database of RefSeq genes. • 34652 UniProtKB/TrEMBL • Q0E8R1 Q3YBY4 Q8SXD5 Q8SZ36
Other Crossreferences
	BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE18101
Linkouts
	BioGRID - A database of protein and genetic interactions • 60700 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0043841 DroID - A comprehensive database of gene and protein interactions. • FBgn0043841 DRSC - Results from RNAi screens. • FBgn0043841 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0043841 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG31764-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0043841 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34652 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34652 modMine - Data generated by the modENCODE project. • FBgn0043841
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	BEST:GH02216 (Zou et al., 2000, ) CG5453 (Freeman et al., 2003, ) CG15493 (Gruenewald et al., 2009) CG31764 (Dostert et al., 2005, Imler, 2005.7.25, Kearney et al., 2004, FlyBase, 1996-, Zhang et al., 2006, Hansen et al., 2009, Keleman et al., 2009.8.5, Tomancak et al., 2007, Cammarato et al., 2011, Tsai et al., 2008, Rehwinkel et al., 2004) vir-1 (Fischer et al., 2012, Nakamoto et al., 2012, Blanco et al., 2010, Arbouzova and Zeidler, 2006, Saleh et al., 2009, Galiana-Arnoux et al., 2006, Deddouche et al., 2008, Hansen et al., 2009, Tsai et al., 2008, Hedges and Johnson, 2008) vir1 (Carpenter et al., 2009) Vir-1 (Goto et al., 2010)
Name Synonym	vir-1 (Zhang et al., 2006) virus-induced 1 (Dostert and Imler, 2005.7.25) virus-induced RNA 1 (Imler, 2005.7.25, Arbouzova and Zeidler, 2006, Cammarato et al., 2011)
Secondary FlyBase IDs
	FBgn0032426 FBgn0032427 FBgn0051764
References ( 47 )
Generate a list of	All references relating to this gene ( 47 )
List References by type	Research paper  ( 24 ) Supplementary material  ( 7 ) Review  ( 2 ) Personal communication to FlyBase  ( 9 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 1 ) Website  ( 1 )
Recent research papers ( 7 )
	Kemp et al., 2013, J. Immunol. 190(2): 650--658 Broad RNA interference-mediated antiviral immunity and virus-specific inducible responses in Drosophila. [FBrf0220316] Fischer et al., 2012, Proc. Biol. Sci. 279(1738): 2636--2644 Conserved properties of Drosophila and human spermatozoal mRNA repertoires. [FBrf0218415] Krauchunas et al., 2012, Dev. Biol. 370(1): 125--134 Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. [FBrf0219342] Nakamoto et al., 2012, Immunity 36(4): 658--667 Virus recognition by toll-7 activates antiviral autophagy in Drosophila. [FBrf0218107] Spasic et al., 2012, PLoS Genet. 8(1): e1002433 Genome-Wide Assessment of AU-Rich Elements by the AREScore Algorithm. [FBrf0217189] Weber et al., 2012, PLoS ONE 7(4): e34745 Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster. [FBrf0218073] Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784 GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...