A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\412\ORF3

General Information
SymbolDmel\412\ORF3SpeciesD. melanogaster
NameORF3Annotation symbol
Feature typetransposable_element_geneFlyBase IDFBgn0043847
Created / Updated2006-08-22/2007-09-12
Genomic Location
Chromosome (arm)Recombination map
Cytogenetic mapSequence location
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Automatically generated summary

See sections below for more information
The gene ORF3 is referred to in FlyBase by the symbol 412\ORF3 (FBgn0043847). It has not been localized to the genome sequence. Its molecular function is described as: RNA-directed DNA polymerase activity; RNA binding; DNA binding; aspartic-type endopeptidase activity. It is involved in the biological processes: RNA-dependent DNA replication; proteolysis; DNA integration. No alleles are reported. It has no annotated transcripts.
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FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
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Comments on Gene Model
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Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
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Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
RNA-directed DNA polymerase (reverse transcriptase) (IPR000477)
Integrase, catalytic core (IPR001584)
Peptidase aspartic, active site (IPR001969)
Peptidase A2A, retrovirus, catalytic (IPR001995)
Peptidase aspartic, catalytic (IPR009007)
Polynucleotidyl transferase, Ribonuclease H fold (IPR012337)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AY928609
AAX28841
 
X04132
CAA27750
 
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Maps to
Does NOT map to
Identified with
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Type
Symbol & Location
Additional Notes
References
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Linkouts
Crossreferences
hide Expression Data
FlyBase-Curated Data
Transcript and
Protein data 		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
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Stage
Tissue/Position
Reference
Marker for
    Subcellular Localization
    CV Term
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    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
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      Linkouts
      FLIGHT - Cell culture data for RNAi and other high-throughput technologies
      •
      hide Alleles & Phenotypes
      hide Summary of Allele Phenotypes
      Phenotype manifest in
      Allele
      hide Classical Alleles ( 0 )
      For All Classical Alleles Show

      Allele of 412\ORF3ClassMutagenStocksKnown lesion
      hide Alleles Carried on Transgenic Constructs ( 0 )
      For All Alleles Carried on Transgenic Constructs Show

      Allele of 412\ORF3ClassMutagenStocksKnown lesion
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      Transgenic Constructs
      Type of construct
      Name
      Expression data
      Insertions
      Type of insertions
      Name
      Expression data
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      Please look at the allele reports for the complete phenotype data
      hide Gene Ontology: Function, Process & Cellular Component ( 7 )
      hide Molecular Function
      CV term
      Evidence
      References
      DNA binding
      inferred from electronic annotation with InterPro:IPR001584
      (FlyBase Curators et al., 2004-)
      RNA binding
      inferred from electronic annotation with InterPro:IPR000477
      (FlyBase Curators et al., 2004-)
      RNA-directed DNA polymerase activity
      inferred from electronic annotation with InterPro:IPR000477
      (FlyBase Curators et al., 2004-)
      aspartic-type endopeptidase activity
      inferred from electronic annotation with InterPro:IPR001969, InterPro:IPR001995, InterPro:IPR009007
      (FlyBase Curators et al., 2004-)
      hide Biological Process
      CV term
      Evidence
      References
      DNA integration
      inferred from electronic annotation with InterPro:IPR001584
      (FlyBase Curators et al., 2004-)
      RNA-dependent DNA replication
      inferred from electronic annotation with InterPro:IPR000477
      (FlyBase Curators et al., 2004-)
      proteolysis
      inferred from electronic annotation with InterPro:IPR001969, InterPro:IPR001995, InterPro:IPR009007
      (FlyBase Curators et al., 2004-)
      hide Cellular Component
      CV term
      Evidence
      References
      hide Sequence Ontology: Class of Gene
      transposable_element_gene
       
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      Interacts with
      Please look at the allele data for full details of the genetic interactions
      412\ORF3 allele
      Gene
      References
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      Linkouts
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      Genome-wide drosophilid orthologs
      Curated drosophilid orthologs
      Linkouts
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      Produces phenotype in
      Produces NO phenotype in
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      hide Stocks Listed in FlyBase ( 0 )
      hide Genomic Clones ( 0 )
      hide cDNA Clones ( 0 )
      cDNA Clones, Fully Sequenced
      BDGP DGC clones
      Other clones
      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
      Other clones
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      Affy Oligo
      Linkouts
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      Source for database identity of
      Source for database merge of
      Encoded by
      412
       
      Additional comments
      hide Comments About Role
      hide Comments About Molecular Function
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      hide External Crossreferences & Linkouts
      Sequence Crossreferences
      DDBJ / EMBL / GenBank
      •
      UniProtKB/Swiss-Prot
      •
      UniProtKB/TrEMBL
      •
      Other Crossreferences
      InterPro domains - A database of protein families, domains, and functional sites
      •
      RNA-directed DNA polymerase (reverse transcriptase) (IPR000477)
      Integrase, catalytic core (IPR001584)
      Peptidase aspartic, active site (IPR001969)
      Peptidase A2A, retrovirus, catalytic (IPR001995)
      Peptidase aspartic, catalytic (IPR009007)
      Polynucleotidyl transferase, Ribonuclease H fold (IPR012337)
      Linkouts
      FLIGHT - Cell culture data for RNAi and other high-throughput technologies
      •
      hide Synonyms & Secondary IDs ( 2 )
      Reported As
      Symbol Synonym
      412\ORF3
       
      ORF3
      (Saito et al., 2006)
      Name Synonym
      ORF3
       
      Secondary FlyBase IDs
        hide References ( 2 )
        Research paper
        Saito et al., 2006, Genes Dev. 20(16): 2214--2222
        Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. [FBrf0191820]
        Personal communication to FlyBase
        FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.
        Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]