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Gene Dmel\Ilp5

General Information
Symbol	Dmel\Ilp5	Species	D. melanogaster
Name	Insulin-like peptide 5	Annotation symbol	CG33273
Feature type	protein_coding_gene	FlyBase ID	FBgn0044048
Gene Model Status	Current	Stock availability	11 publicly available
Also Known As	dilp5, DILP, dILP-5, Ilp-5
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	67C9-67C9	Sequence location	3L:9,816,449..9,816,997 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Insulin-like peptide 5 is referred to in FlyBase by the symbol Dmel\Ilp5 (CG33273, FBgn0044048). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: insulin receptor binding. There is experimental evidence that it is involved in the biological process: female mating behavior. 9 alleles are reported. The phenotype of these alleles is annotated with: embryonic/larval neuroblast. It has one annotated transcript and one annotated polypeptide. Protein features are: Insulin family; Insulin, conserved site; Insulin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed at stages throughout the larval period, during early pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval Malpighian tubules. Comments on Affy2 ProbeSet: ProbeSet 1624745_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Ilp5. Gene sequence location is 3L:9816449..9816997.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 67C9-67C9   Limits computationally determined from genome sequence between P{PZ}fry02240 and P{lacW}l(3)L0539L0539&P{PZ}Dhh1rL562 67C9
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Ilp5 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Ilp5-RA FBtr0076371  NM_206315   478   107
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Ilp5-PA   FBpp0076100   11.8   107   7.80     NP_996037   AAS65048
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Insulin-like (IPR016179) Insulin family (IPR022352) Insulin, conserved site (IPR022353)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAS65048   BT032927   BT032948
UniProtKB/Swiss-Prot	Q7KUD5
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference second instar larval stage -- third instar larval stage   dorsomedial neurosecretory cell of pars intercerebralis   (Ikeya et al., 2002) third instar larval stage   embryonic/larval brain | anterior & medial & restricted   (Brogiolo et al., 2001) embryonic/larval midgut   (Brogiolo et al., 2001) adult stage   dorsomedial neurosecretory cell   (Broughton et al., 2005)
Additional Descriptive Data
	Transcript is detected at high levels in seven cells in each brain hemisphere in an anterior-medial postion and at low levels in the gut. (Brogiolo et al., 2001) Ilp5 is expressed in a bilaterally symmetrical cluster of 5 to 7 neurosecretory cells in the pars intercerebralis. It is co-expressed with Ilp3 and Ilp2. (Broughton et al., 2005) Transcript is expressed in two clusters of cells in the pars intercerebralis corresponding to the medial neurosecretory cell clusters (m-NSCs) from the mid-late third larval instar. (Ikeya et al., 2002)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval Malpighian tubules. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    630.75 Larval Midgut    9.1 Larval Hindgut    8.7 Larval Malpighian Tubules    286.1 Larval Fat Body    16.2 Larval Salivary Gland    10.5 Larval Trachea    4.3 Larval Carcass    10.825 Adult Head    184.8 Adult Eye    4.775 Adult Brain    683 Adult Thoracic-Abdominal Ganglion    4.5 Adult Crop    9.8 Adult Midgut    12 Adult Hindgut    7 Adult Malpighian Tubules    10.3 Adult Fat Body    8.8 Adult Salivary Gland    10.1 Adult Heart    2.925 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    5.7 Adult Ovary    4.4 Adult Testis    6.5 Adult Male Accessory Gland    10.4 Adult Carcass    15.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (630.75) Larval Midgut    9.1 Larval Hindgut    8.7 Larval Malpighian Tubules    286.1 Larval Fat Body    16.2 Larval Salivary Gland    10.5 Larval Trachea    4.3 Larval Carcass    10.825 Adult Head    184.8 Adult Eye    4.775 Adult Brain  (683) Adult Thoracic-Abdominal Ganglion    4.5 Adult Crop    9.8 Adult Midgut    12 Adult Hindgut    7 Adult Malpighian Tubules    10.3 Adult Fat Body    8.8 Adult Salivary Gland    10.1 Adult Heart    2.925 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    5.7 Adult Ovary    4.4 Adult Testis    6.5 Adult Male Accessory Gland    10.4 Adult Carcass    15.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    630.75 Larval Midgut    9.1 Larval Hindgut    8.7 Larval Malpighian Tubules    286.1 Larval Fat Body    16.2 Larval Salivary Gland    10.5 Larval Trachea    4.3 Larval Carcass    10.825 Adult Head    184.8 Adult Eye    4.775 Adult Brain    683 Adult Thoracic-Abdominal Ganglion    4.5 Adult Crop    9.8 Adult Midgut    12 Adult Hindgut    7 Adult Malpighian Tubules    10.3 Adult Fat Body    8.8 Adult Salivary Gland    10.1 Adult Heart    2.925 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    5.7 Adult Ovary    4.4 Adult Testis    6.5 Adult Male Accessory Gland    10.4 Adult Carcass    15.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    630.75 Larval Midgut    9.1 Larval Hindgut    8.7 Larval Malpighian Tubules    286.1 Larval Fat Body    16.2 Larval Salivary Gland    10.5 Larval Trachea    4.3 Larval Carcass    10.825 Adult Head    184.8 Adult Eye    4.775 Adult Brain    683 Adult Thoracic-Abdominal Ganglion    4.5 Adult Crop    9.8 Adult Midgut    12 Adult Hindgut    7 Adult Malpighian Tubules    10.3 Adult Fat Body    8.8 Adult Salivary Gland    10.1 Adult Heart    2.925 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    5.7 Adult Ovary    4.4 Adult Testis    6.5 Adult Male Accessory Gland    10.4 Adult Carcass    15.3 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    630.75 Larval Midgut    9.1 Larval Hindgut    8.7 Larval Malpighian Tubules    286.1 Larval Fat Body    16.2 Larval Salivary Gland    10.5 Larval Trachea    4.3 Larval Carcass    10.825 Adult Head    184.8 Adult Eye    4.775 Adult Brain    683 Adult Thoracic-Abdominal Ganglion    4.5 Adult Crop    9.8 Adult Midgut    12 Adult Hindgut    7 Adult Malpighian Tubules    10.3 Adult Fat Body    8.8 Adult Salivary Gland    10.1 Adult Heart    2.925 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    5.7 Adult Ovary    4.4 Adult Testis    6.5 Adult Male Accessory Gland    10.4 Adult Carcass    15.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  630.75 Larval Midgut    9.1 Larval Hindgut    8.7 Larval Malpighian Tubules    286.1 Larval Fat Body    16.2 Larval Salivary Gland    10.5 Larval Trachea    4.3 Larval Carcass    10.825 Adult Head    184.8 Adult Eye    4.775 Adult Brain  683 Adult Thoracic-Abdominal Ganglion    4.5 Adult Crop    9.8 Adult Midgut    12 Adult Hindgut    7 Adult Malpighian Tubules    10.3 Adult Fat Body    8.8 Adult Salivary Gland    10.1 Adult Heart    2.925 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    5.7 Adult Ovary    4.4 Adult Testis    6.5 Adult Male Accessory Gland    10.4 Adult Carcass    15.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    630.75 Larval Midgut    9.1 Larval Hindgut    8.7 Larval Malpighian Tubules    286.1 Larval Fat Body    16.2 Larval Salivary Gland    10.5 Larval Trachea    4.3 Larval Carcass    10.825 Adult Head    184.8 Adult Eye    4.775 Adult Brain    683 Adult Thoracic-Abdominal Ganglion    4.5 Adult Crop    9.8 Adult Midgut    12 Adult Hindgut    7 Adult Malpighian Tubules    10.3 Adult Fat Body    8.8 Adult Salivary Gland    10.1 Adult Heart    2.925 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    5.7 Adult Ovary    4.4 Adult Testis    6.5 Adult Male Accessory Gland    10.4 Adult Carcass    15.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    630.75 Larval Midgut    9.1 Larval Hindgut    8.7 Larval Malpighian Tubules    286.1 Larval Fat Body    16.2 Larval Salivary Gland    10.5 Larval Trachea    4.3 Larval Carcass    10.825 Adult Head    184.8 Adult Eye    4.775 Adult Brain    683 Adult Thoracic-Abdominal Ganglion    4.5 Adult Crop    9.8 Adult Midgut    12 Adult Hindgut    7 Adult Malpighian Tubules    10.3 Adult Fat Body    8.8 Adult Salivary Gland    10.1 Adult Heart    2.925 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    5.7 Adult Ovary    4.4 Adult Testis    6.5 Adult Male Accessory Gland    10.4 Adult Carcass    15.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    184.8   NA  Eye    4.775   NA  Brain    683   630.75  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    4.5   NA  Crop    9.8   9.1  Midgut    12   8.7  Hindgut    7   286.1  Malpighian Tubules    no informative data   no informative data  Fat Body    8.8   no informative data  Salivary Gland    no informative data   NA  Heart    2.925   4.3  Trachea    NA   NA  VirginFemale Spermatheca    8.8   NA  InseminatedFemale Spermatheca    5.7   NA  Ovary    4.4   NA  Testis    6.5   NA  Male Accessory Gland    no informative data   no informative data  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    9 central nervous system, pupae P8    0 head, virgin 1-day female    13 head, virgin 4-day female    7 head, virgin 20-day female    19 head, mated 1-day female    7 head, mated 4-day female    10 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    18 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    9 central nervous system, pupae P8    0 head, virgin 1-day female    13 head, virgin 4-day female    7 head, virgin 20-day female    19 head, mated 1-day female    7 head, mated 4-day female    10 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    18 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    9 central nervous system, pupae P8    0 head, virgin 1-day female    13 head, virgin 4-day female    7 head, virgin 20-day female    19 head, mated 1-day female    7 head, mated 4-day female    10 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    18 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    9 central nervous system, pupae P8    0 head, virgin 1-day female    13 head, virgin 4-day female    7 head, virgin 20-day female    19 head, mated 1-day female    7 head, mated 4-day female    10 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    18 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    9 central nervous system, pupae P8    0 head, virgin 1-day female    13 head, virgin 4-day female    7 head, virgin 20-day female    19 head, mated 1-day female    7 head, mated 4-day female    10 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    18 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    9 central nervous system, pupae P8    0 head, virgin 1-day female    13 head, virgin 4-day female    7 head, virgin 20-day female    19 head, mated 1-day female    7 head, mated 4-day female    10 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    18 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    9 central nervous system, pupae P8    0 head, virgin 1-day female    13 head, virgin 4-day female    7 head, virgin 20-day female    19 head, mated 1-day female    7 head, mated 4-day female    10 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    18 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    9 central nervous system, pupae P8    0 head, virgin 1-day female    13 head, virgin 4-day female    7 head, virgin 20-day female    19 head, mated 1-day female    7 head, mated 4-day female    10 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    18 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed at stages throughout the larval period, during early pupal stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    1 larva L2    4 larva L3 12hr old    6 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    7 white prepupae new    7 white prepupae 12hr    6 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    6 adult female 01day    3 adult female 05day    1 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    1 larva L2    4 larva L3 12hr old    6 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    7 white prepupae new    7 white prepupae 12hr    6 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    6 adult female 01day    3 adult female 05day    1 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    1 larva L2    4 larva L3 12hr old    6 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    7 white prepupae new    7 white prepupae 12hr    6 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    6 adult female 01day    3 adult female 05day    1 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    1 larva L2    4 larva L3 12hr old    6 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    7 white prepupae new    7 white prepupae 12hr    6 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    6 adult female 01day    3 adult female 05day    1 adult female 30day    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    1 larva L2    4 larva L3 12hr old    6 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    7 white prepupae new    7 white prepupae 12hr    6 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    6 adult female 01day    3 adult female 05day    1 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    1 larva L2    4 larva L3 12hr old    6 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    7 white prepupae new    7 white prepupae 12hr    6 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    6 adult female 01day    3 adult female 05day    1 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    1 larva L2    4 larva L3 12hr old    6 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    7 white prepupae new    7 white prepupae 12hr    6 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    6 adult female 01day    3 adult female 05day    1 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    1 larva L2    4 larva L3 12hr old    6 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    7 white prepupae new    7 white prepupae 12hr    6 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    4 adult male 30day    6 adult female 01day    3 adult female 05day    1 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    4 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    4 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    4 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    4 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    4 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    4 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    4 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    4 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    0 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    0 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    0 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    0 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    0 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    0 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    0 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    0 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (Graveley et al., 2011) mE1_20_mRNA_expression_cluster_08
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0044048 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • HDC09365
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable Ilp51 viable, with Scer\GAL4pnr-MD237 Ilp5GD16039 Other Phenotypes Allele large body, with Scer\GAL4arm.PS Ilp5Scer\UAS.cIa mating defective Ilp51 Phenotype manifest in Allele embryonic/larval neuroblast, with Scer\GAL4repo.PU Ilp5Scer\UAS.cIa
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of Ilp5 Class Mutagen Stocks Known lesion Ilp53 SCEI endonuclease FLPase ends-out gene targeting 3 Yes Ilp54 SCEI endonuclease FLPase ends-out gene targeting 3 Yes Ilp51 SCEI endonuclease FLPase ends-out gene targeting 1 Yes
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Ilp5 Class Mutagen Stocks Known lesion Ilp5GD16039 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Ilp5HMS00548 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Ilp5JF01347 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Ilp5KK112762 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Ilp5Scer\UAS.cIa in vitro construct - regulatory fusion 0 Yes Ilp5w.Scer\SceI.RS in vitro construct 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)AC1 (Brogiolo et al., 2001) Df(3L)Ilp1-5 (Zhang et al., 2009)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD16039} NA P{KK112762} NA P{TRiP.HMS00548} NA P{TRiP.JF01347} NA P{UAS-Ilp5.I} NA reporter construct P{pXD51X} No P{pXD51XB} No
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
female mating behavior inferred from mutant phenotype (Wigby et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
hormone activity inferred from electronic annotation with InterPro:IPR016179 (FlyBase Curators et al., 2004-) insulin receptor binding inferred from sequence or structural similarity with human INS (Brogiolo et al., 2001) inferred from sequence or structural similarity with UniProtKB:P22334 (FlyBase Genome Annotators, 2004)
Biological Process
CV term Evidence References
insulin receptor signaling pathway inferred from sequence or structural similarity with human INS (Brogiolo et al., 2001)
Cellular Component
CV term Evidence References
extracellular region inferred from sequence or structural similarity with human INS (Brogiolo et al., 2001)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Ilp5 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0044048 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 2768992 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • Q7KUD5
Orthologs
OrthoDB Orthologs (14) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6NCN0F Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search EOG6JSZ39 Arthropod inclusive ortholog search EOG6JM669 Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6NCN0F)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Ilp5     Drosophila simulans   Dsim\GD12890 Y   Drosophila sechellia   Dsec\GM24838 Y   Drosophila erecta   Dere\GG14004 Y   Drosophila yakuba   Dyak\GE20299 Y   Drosophila ananassae   Dana\GF20100     Drosophila pseudoobscura pseudoobscura   Dpse\GA23860 Y   Drosophila persimilis   Dper\GL16323 Y   Drosophila virilis   Dvir\GJ13215 Y   Drosophila mojavensis   Dmoj\GI12279 Y   Drosophila grimshawi   Dgri\GH16013 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (EOG6JSZ39)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Bombyx mori Silkmoth  Bmor\BGIBMGA012476
Orthologs in non-Insect Arthropods (EOG6JM669)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Olr1301 Y Ixodes scapularis Deer tick  Isca\ISCW020331 Y
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (9) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD12890 Drosophila sechellia Dsec\GM24838 Drosophila erecta Dere\GG14004 Drosophila yakuba Dyak\GE20299 Drosophila pseudoobscura pseudoobscura Dpse\GA23860 Drosophila persimilis Dper\GL16323 Drosophila virilis Dvir\GJ13215 Drosophila mojavensis Dmoj\GI12279 Drosophila grimshawi Dgri\GH16013
Stocks & Reagents
Stocks Listed in FlyBase ( 11 )
Bloomington	30884 w1118; Ilp51 31378 y1 v1; P{TRiP.JF01347}attP2 33683 y1 sc* v1; P{TRiP.HMS00548}attP2 30889 w1118; Df(3L)Ilp2-3, Ilp53/TM3, Sb1 30890 w1118; Df(3L)Ilp1-4, Ilp54/TM3, Sb1 30893 w1118 Ilp71; Df(3L)Ilp2-3, Ilp53/TM3, Sb1 30894 w1118 Ilp71; Df(3L)Ilp1-4, Ilp54/TM3, Sb1 30891 Df(1)Ilp668, y1 phl68 w1118; Df(3L)Ilp2-3, Ilp53/TM3, Sb1 30892 Df(1)Ilp641, y1 Ilp641 phl41 w1118; Df(3L)Ilp2-3, Ilp54/TM3, Sb1
VDRC	v105004 P{KK112762}VIE-260B v49520 w1118; P{GD16039}v49520
Genomic Clones ( 2 )
	BACR07A05 BACR07E07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 2 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	IP20266 IP20566
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0044048 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 2768992
Antibody Information
	polyclonal (Géminard et al., 2009, Söderberg et al., 2011, Broughton et al., 2010)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	New annotation (CG33273) in release 3.2 of the genome annotation. (FlyBase Genome Annotators, 2004)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_206315 RefSeq (Proteins) • NP_996037 DDBJ / EMBL / GenBank • AAS65048 Entrez Gene - A searchable database of RefSeq genes. • 2768992 UniProtKB/Swiss-Prot • Q7KUD5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Insulin-like (IPR016179) Insulin family (IPR022352) Insulin, conserved site (IPR022353)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0044048 DRSC - Results from RNAi screens. • FBgn0044048 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0044048 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • HDC09365 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0044048 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 2768992 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 2768992 modMine - Data generated by the modENCODE project. • FBgn0044048 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • Q7KUD5
Synonyms & Secondary IDs ( 24 )
Reported As
Symbol Synonym	CG33273 (Keleman et al., 2009.8.5, Ni et al., 2008, Ni et al., 2010.12.1) DILP (Wu et al., 2005, Nijhout, 2003, Nijhout, 2003) dilp (Belawat and Hafen, 2005) Dilp (Bradley and Leevers, 2003, Rhea et al., 2007) dILP-5 (Teleman and Cohen, 2006) dilp5 (Broughton et al., 2005, Tatar et al., 2003, Ikeya et al., 2002, Rulifson et al., 2002, Ikeya and Hafen, 2002, Brogiolo et al., 2001, Min et al., 2007, Flatt et al., 2005, Libert, 2007, Karpac et al., 2009, Mattaliano et al., 2007, Slack et al., 2010, Haselton et al., 2010, Söderberg et al., 2011, Guirao-Rico and Aguadé, 2011, Fridell et al., 2009, Slack et al., 2011, Sheldon et al., 2011, Karpac et al., 2011, Mann et al., 2012, Flatt et al., 2008, Broughton et al., 2008, Humphrey et al., 2009, Buch et al., 2008, Okamoto et al., 2009, Clements et al., 2008, Hull-Thompson et al., 2009, Giannakou et al., 2007, Zhang et al., 2009, Grönke et al., 2010, De Luca et al., 2010, Sekine et al., 2010, Wigby et al., 2011, Alic et al., 2011, Wang et al., 2008, McClure et al., 2011, Rideout et al., 2012, Marshall et al., 2012, Yu et al., 2012) dilp-5 (Hwangbo et al., 2004) Dilp 5 (Claeys et al., 2002) DILP5 (Leevers, 2001, Slaidina et al., 2009, Broughton et al., 2010, Sajid et al., 2011) Dilp-5 (Hoshizaki and Gibbs, 2007) Dilp5 (Rajan and Perrimon, 2012, Géminard et al., 2009, Birse et al., 2011, Lee et al., 2008, Wang et al., 2009, Arquier et al., 2008, Demontis and Perrimon, 2010, Okamoto et al., 2013) dILP5 (Wang et al., 2011, Teleman et al., 2008) dIlp5 (Boyd et al., 2011) Ilp (Edgar, 2006) Ilp5 (FlyBase Curators et al., 2004-, Gronke, 2010.5.12, Sousa-Nunes et al., 2011, Okamoto et al., 2013, Thomas et al., 2012) ilp5 (Song et al., 2010, Min et al., 2008, Varghese et al., 2010, Wang et al., 2008, Kim et al., 2008) Ilp-5 (Veenstra et al., 2008, Pospisilik et al., 2010) ILP5 (Hahn et al., 2010)
Name Synonym	Drosophila insulin-like peptide 5 (Oldham and Hafen, 2003) insulin-like peptide (Flatt et al., 2005) insulin-like peptide 5 (Brogiolo et al., 2001) Insulin-like peptide 5   insulin-like peptide-5 (Min et al., 2008) insulin like peptide 5 (Dalton et al., 2010)
Secondary FlyBase IDs
	FBgn0053273
References ( 95 )
Generate a list of	All references relating to this gene ( 95 )
List References by type	Research paper  ( 67 ) Supplementary material  ( 3 ) Review  ( 11 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 5 ) FlyBase analysis  ( 1 ) Conference report  ( 2 )
Recent research papers ( 26 )
	Okamoto et al., 2013, Genes Dev. 27(1): 87--97 A secreted decoy of InR antagonizes insulin/IGF signaling to restrict body growth in Drosophila. [FBrf0220509] Fabian et al., 2012, Mol. Ecol. 21(19): 4748--4769 Genome-wide patterns of latitudinal differentiation among populations of Drosophila melanogaster from North America. [FBrf0219505] Mann et al., 2012, Development 139(4): 760--771 A putative tyrosine phosphorylation site of the cell surface receptor Golden goal is involved in synaptic layer selection in the visual system. [FBrf0217291] Marshall et al., 2012, EMBO J. 31(8): 1916--1930 Nutrient/TOR-dependent regulation of RNA polymerase III controls tissue and organismal growth in Drosophila. [FBrf0218035] Okamoto et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(7): 2406--2411 Conserved role for the Dachshund protein with Drosophila Pax6 homolog Eyeless in insulin expression. [FBrf0217470] Rajan and Perrimon, 2012, Cell 151(1): 123--137 Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion. [FBrf0219535] Rideout et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(4): 1139--1144 Drosophila RNA polymerase III repressor Maf1 controls body size and developmental timing by modulating tRNAiMet synthesis and systemic insulin signaling. [FBrf0217359] Stafford et al., 2012, J. Neurosci. 32(42): 14767--14774 Integration of taste and calorie sensing in Drosophila. [FBrf0219704] Thomas et al., 2012, PLoS ONE 7(7): e40276 A Versatile Method for Cell-Specific Profiling of Translated mRNAs in Drosophila. [FBrf0218903] Thomson et al., 2012, genesis 50(6): 453--465 Oocyte destruction is activated during viral infection. [FBrf0218617] Yu et al., 2012, Mol. Cell. Biol. 32(18): 3610--3623 Neuronal Cbl Controls Biosynthesis of Insulin-Like Peptides in Drosophila melanogaster. [FBrf0219284] Alic et al., 2011, Aging Cell 10(1): 137--147 Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor. [FBrf0212768] Birse et al., 2011, J. Exp. Biol. 214(24): 4201--4208 Regulation of insulin-producing cells in the adult Drosophila brain via the tachykinin peptide receptor DTKR. [FBrf0216793] Boyd et al., 2011, Free Radical Biol. Med. 50(11): 1669--1678 Nectarine promotes longevity in Drosophila melanogaster. [FBrf0213612] Guirao-Rico and Aguadé, 2011, Mol. Biol. Evol. 28(5): 1557--1560 Molecular evolution of the ligands of the insulin-signaling pathway: dilp genes in the genus drosophila. [FBrf0214497] Karpac et al., 2011, Dev. Cell 20(6): 841--854 Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage. [FBrf0213873] McClure et al., 2011, Dis. Model Mech. 4(3): 335--346 A Drosophila model for fetal alcohol syndrome disorders: role for the insulin pathway. [FBrf0213698] O'Brien et al., 2011, Cell 147(3): 603--614 Altered modes of stem cell division drive adaptive intestinal growth. [FBrf0216512] Sajid et al., 2011, J. Biol. Chem. 286(1): 661--673 Structural and Biological Properties of the Drosophila Insulin-like Peptide 5 Show Evolutionary Conservation. [FBrf0212648] Sheldon et al., 2011, PLoS ONE 6(8): e23343 SLOB, a SLOWPOKE Channel Binding Protein, Regulates Insulin Pathway Signaling and Metabolism in Drosophila. [FBrf0214706] Shin et al., 2011, Science 334(6056): 670--674 Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling. [FBrf0216582] Slack et al., 2011, Aging Cell 10(5): 735--748 dFOXO-independent effects of reduced insulin-like signaling in Drosophila. [FBrf0215229] Sousa-Nunes et al., 2011, Nature 471(7339): 508--512 Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila. [FBrf0214426] Söderberg et al., 2011, PLoS ONE 6(5): e19866 Insulin Production and Signaling in Renal Tubules of Drosophila Is under Control of Tachykinin-Related Peptide and Regulates Stress Resistance. [FBrf0213657] Wang et al., 2011, Cell Cycle 10(16): 2628--2634 Regulation of adult stem cell behavior by nutrient signaling. [FBrf0214811] Wigby et al., 2011, Proc. Biol. Sci. 278(1704): 424--431 Insulin signalling regulates remating in female Drosophila. [FBrf0212666] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...