FlyBase Gene Report: Hsap\KCNJ2

General Information

Symbol

Hsap\KCNJ2

Species

H. sapiens

Name

potassium inwardly-rectifying channel, subfamily J, member 2

Annotation Symbol

Feature Type

engineered_foreign_gene

FlyBase ID

FBgn0044439

Gene Model Status

Not Applicable

Stock Availability

5 publicly available

Other Summaries

Alliance
Auto summary
Interactive Fly

Also Known As

Kir2.1

Tag or Foreign Gene Data

Foreign sequence; species == Homo sapiens; gene == KCNJ2; HGNC:6263.

(FlyBase Curators, 1992-)

Function

GO Summary Ribbons

[Detailed GO annotations]

Protein Family (UniProt)

Protein Signatures (InterPro)

Molecular Function (GO)
[Detailed GO annotations]

Experimental Evidence

Predictions / Assertions

Summaries

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Sequence Ontology: Class of Gene

engineered_foreign_gene

Transcript Data

Annotated Transcripts

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Polypeptides with Identical Sequences

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Hsap\KCNJ2 using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Gene Ontology (0 terms)

Molecular Function (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Hsap\KCNJ2 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Hsap\KCNJ2

View exonic expression by tissue for Hsap\KCNJ2

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 0 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 20 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Hsap\KCNJ2

Transgenic constructs containing regulatory region of Hsap\KCNJ2

Deletions and Duplications ( 0 )

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Alp4-c232

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^DAT.PL

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^dimm-929

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^elav-C155

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^ey-OK107

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^GH86

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^GH146

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^GMR78G02

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^GMR.PF

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^H24

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^Ilp2.215-3

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^Mef2.247

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^Mz520

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^NP6510

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^NP6561

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^OK348

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^R6

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^Tab2-201Y

Hsap\KCNJ2^UAS.EGFP

lethal - all die before end of larval stage, with Scer\GAL4^dimm-929

Hsap\KCNJ2^UAS.EGFP

lethal - all die before end of larval stage, with Scer\GAL4^dimm-929, Scer\GAL80^CCAP.PL

Hsap\KCNJ2^UAS.EGFP

partially lethal - majority die, with Scer\GAL4^Burs.PP

Hsap\KCNJ2^UAS.EGFP

partially lethal - majority die | heat sensitive, with Scer\GAL4^Burs.PP, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

Sterility

Allele

female sterile, with Scer\GAL4^Ilp7.PY

Hsap\KCNJ2^UAS.EGFP

female sterile, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

male sterile, with Scer\GAL4^Crz.391

Hsap\KCNJ2^UAS.EGFP

male sterile, with Scer\GAL4^CrzR.3.5

Hsap\KCNJ2^UAS.EGFP

male sterile, with Scer\GAL4^Trh.1.0

Hsap\KCNJ2^UAS.EGFP

Other Phenotypes

Allele

behavior defective, with Scer\FLP1^fru, Scer\GAL4^5-HT1B.PY

Hsap\KCNJ2^UAS.GFP

behavior defective, with Scer\GAL4^5-HT1B.PY

Hsap\KCNJ2^UAS.EGFP

behavior defective, with Scer\GAL4^ppk29.3.612

Hsap\KCNJ2^UAS.EGFP

behavior defective, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

behavior defective | adult stage, with Ecol\lexA^fru.P1, Scer\GAL4^Tk

Hsap\KCNJ2^UAS.EGFP.cDa

behavior defective | adult stage, with Scer\GAL4^GMR22C06

Hsap\KCNJ2^UAS.EGFP

behavior defective | adult stage, with Scer\GAL4^GMR24G07

Hsap\KCNJ2^UAS.EGFP

behavior defective | adult stage, with Scer\GAL4^NPF.1

Hsap\KCNJ2^UAS.EGFP

behavior defective | RU486 conditional, with Scer\GAL4^{Mef2.247.Switch}

Hsap\KCNJ2^UAS.EGFP

chemical resistant, with Scer\GAL4^Crz.PU

Hsap\KCNJ2^UAS.EGFP

chemical resistant, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr61a.4.9, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr64f.9.7, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL4^NP0534, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^4.64

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^10.229

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^17d

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^GMR79D04

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^Gr5a.8.5

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^Gr33a-GAL4

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^Gr61a.4.9

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^Gr64e.8

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^Gr64f.9.7

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^{Orco.2.642.Hsim\VP22}

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage, with Scer\GAL4^TrpA1.PR

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage | female limited, with Ecol\lexA^Gr66a.PU, Ecol\lexA^VP16.Gr64f, Scer\GAL4^Ir76b.1.5, Scer\GAL80^{ts.lexAop.cTa}

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage | female limited, with Scer\GAL4^Ir76b.1.5

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | adult stage | nutrition conditional, with Scer\GAL4^GMR38H02

Hsap\KCNJ2^UAS.cUa.EGFP

chemosensitive behavior defective | adult stage | nutrition conditional, with Scer\GAL4^SLC5A11.1.1

Hsap\KCNJ2^UAS.cUa.EGFP

chemosensitive behavior defective | larval stage, with Hsap\RELA^AD.R48F09, Scer\GAL4^DBD.R27A11

Hsap\KCNJ2^5XUAS.EGFP

chemosensitive behavior defective | larval stage, with Scer\GAL4^Ir60c.PC

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | larval stage, with Scer\GAL4^odd-MC

Hsap\KCNJ2^UAS.EGFP

chemosensitive behavior defective | larval stage | conditional, with Hsap\RELA^AD.R14E06, Scer\GAL4^DBD.R27G01

Hsap\KCNJ2^5XUAS.EGFP

circadian behavior defective | adult stage, with Scer\GAL4^S3.Hug

Hsap\KCNJ2^UAS.EGFP

copulation defective, with Scer\FLP1^fru, Scer\GAL4^VGlut-OK371, Scer\GAL80^tsh-GAL80

Hsap\KCNJ2^{FRT.Stop.UAS.EGFP}

copulation defective | adult stage, with Scer\GAL4^{VGlut.VGN9281}

Hsap\KCNJ2^UAS.EGFP

courtship behavior defective, with Scer\FLP1^fru, Scer\GAL4^VGlut-OK371, Scer\GAL80^tsh-GAL80

Hsap\KCNJ2^{FRT.Stop.UAS.EGFP}

courtship behavior defective, with Scer\GAL4^NPF.1

Hsap\KCNJ2^UAS.EGFP

courtship behavior defective | adult stage | male limited, with Scer\GAL4^{VGlut.VGN9281}

Hsap\KCNJ2^UAS.EGFP

developmental rate defective | larval stage, with Scer\GAL4^Ptth.cMa

Hsap\KCNJ2^UAS.EGFP

eclosion rhythm defective, with Scer\GAL4^Ptth.cMa

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage, with Ecol\lexA^GMR65C11, Scer\GAL4^Gr28b.b.4.7, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.cUa.EGFP

feeding behavior defective | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL4^NP0534, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL4^VT005008, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage, with Scer\GAL4^0098-G4

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage, with Scer\GAL4^0179-G4

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage, with Scer\GAL4^0301-G4

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage, with Scer\GAL4^Ae2-0178-G4

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage, with Scer\GAL4^Gr28b.b.4.7

Hsap\KCNJ2^UAS.cUa.EGFP

feeding behavior defective | adult stage, with Scer\GAL4^NP1562

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage, with Scer\GAL4^{Sema1a-0156-G4}

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage, with Scer\GAL4^SLC5A11.1.1

Hsap\KCNJ2^UAS.cUa.EGFP

feeding behavior defective | adult stage, with Scer\GAL4^tara-0116-G4

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage | heat sensitive, with Scer\GAL4^Alp4-c232

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage | heat sensitive, with Scer\GAL4^GMR15B07

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage | heat sensitive, with Scer\GAL4^GMR38H02

Hsap\KCNJ2^UAS.EGFP

feeding behavior defective | adult stage | heat sensitive, with Scer\GAL4^SLC5A11.1.1

Hsap\KCNJ2^UAS.EGFP

flight defective, with Scer\GAL4^Trh.PB

Hsap\KCNJ2^UAS.EGFP

flightless, with Scer\GAL4^GMR67E06

Hsap\KCNJ2^UAS.EGFP

flightless, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

flightless, with Scer\GAL4^ple.TH-C'

Hsap\KCNJ2^UAS.EGFP

flightless, with Scer\GAL4^{VGlut.VGN9281}

Hsap\KCNJ2^UAS.EGFP

heat stress response defective | larval stage, with Scer\GAL4^ppk.PG

Hsap\KCNJ2^UAS.EGFP

hyperactive | larval stage, with Scer\GAL4^ppk.PG

Hsap\KCNJ2^UAS.EGFP

hyperactive | larval stage | chemical conditional, with Scer\GAL4^odd-MC

Hsap\KCNJ2^UAS.EGFP

hypoactive | adult stage, with Scer\GAL4^NP0895

Hsap\KCNJ2^UAS.EGFP

hypoactive | adult stage, with Scer\GAL4^S3.Hug

Hsap\KCNJ2^UAS.EGFP

hypoactive | larval stage, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

hypoactive | larval stage, with Scer\GAL4^P2.4.Pdf, Scer\GAL4^eve.RN2

Hsap\KCNJ2^UAS.EGFP

increased occurrence of cell division, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

jump response defective, with Hsap\RELA^AD.R19G02, Scer\GAL4^DBD.R75G12

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

jump response defective | adult stage, with Hsap\RELA^AD.R17A04, Scer\GAL4^DBD.R68A06

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

jump response defective | adult stage, with Hsap\RELA^AD.R17A04, Scer\GAL4^DBD.R79H02

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

jump response defective | adult stage, with Hsap\RELA^AD.R48H08, Scer\GAL4^DBD.R29G11

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

jump response defective | adult stage | conditional, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

jump response defective | adult stage | conditional, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R86D05

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

jump response defective | adult stage | conditional, with Hsap\RELA^AD.R49C04, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

locomotor behavior defective | adult stage, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr61a.4.9, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr64f.9.7, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Hsap\RELA^AD.R19G02, Scer\GAL4^DBD.R70G12

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

locomotor behavior defective | adult stage, with Hsap\RELA^AD.R27F02, Scer\GAL4^DBD.R19G02

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

locomotor behavior defective | adult stage, with Hsap\RELA^AD.R27F02, Scer\GAL4^DBD.R60D05

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

locomotor behavior defective | adult stage, with Scer\GAL4^238Y

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^E564

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^GMR30G08

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^GMR38E07

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^GMR49H02

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^GMR79D04

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^GMR85A11

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^GMR89E07

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^Gr5a.8.5

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^Gr61a.4.9

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^Gr64e.8

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^Gr64f.9.7

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^iav.PK

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^NP0895

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^NP1619

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^NP3069

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^ple.PU

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage, with Scer\GAL4^Tdc2.PC

locomotor behavior defective | adult stage | heat sensitive, with Scer\GAL4^Ddc.HL9

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | adult stage | heat sensitive, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | larval stage, with Scer\GAL4^iav.PP

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | larval stage, with Scer\GAL4^odd-MC

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | larval stage, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | third instar larval stage, with Scer\GAL4^dimm-929

Hsap\KCNJ2^UAS.EGFP

locomotor behavior defective | third instar larval stage | heat sensitive, with Scer\GAL4^elav.PLu, Scer\GAL80^tsh-GAL80

Hsap\KCNJ2^UAS.EGFP

locomotor rhythm defective, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

locomotor rhythm defective, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

locomotor rhythm defective | adult stage, with Hsap\RELA^AD.R12G04, Scer\GAL4^DBD.R18D09

Hsap\KCNJ2^UAS.EGFP

locomotor rhythm defective | adult stage, with Scer\GAL4^Dvir\Pdf.1.9

Hsap\KCNJ2^UAS.EGFP

locomotor rhythm defective | adult stage, with Scer\GAL4^GMR65C07

Hsap\KCNJ2^UAS.EGFP

locomotor rhythm defective | adult stage, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

locomotor rhythm defective | adult stage, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

locomotor rhythm defective | adult stage, with Scer\GAL80^Pdf.PS

Hsap\KCNJ2^UAS.EGFP

locomotor rhythm defective | RU486 conditional, with Scer\GAL4^Pdf.Switch1a

Hsap\KCNJ2^UAS.EGFP

mating behavior defective | male, with Scer\GAL4^{VP16.natalisin}

Hsap\KCNJ2^UAS.EGFP

mating behavior defective | male limited | somatic clone, with Scer\GAL4^GMR21A01

Hsap\KCNJ2^10x.UAS.GFP

memory defective | adult stage, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr64f.9.7, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^GMR18H09

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^GMR32G08

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^GMR66A09

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^GMR76B09

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^GMR76B09, Scer\GAL4^NP2397

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^GMR94F11

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^NP2397

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^NP2397, Scer\GAL80^ple.PK

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^NP2397, Scer\GAL80^R48B04

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^NP2397, Scer\GAL80^VGlut.PV

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^NP2758

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^NP7177

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^VT026001

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^VT028152

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage, with Scer\GAL4^VT040039

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage | heat sensitive, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

memory defective | adult stage | RU486 conditional, with Scer\GAL4^{Mef2.247.Switch}

Hsap\KCNJ2^UAS.cUa.EGFP

memory defective | larval stage, with Hsap\RELA^AD.R21D02, Scer\GAL4^DBD.R55D08

Hsap\KCNJ2^5XUAS.EGFP

memory defective | larval stage, with Hsap\RELA^AD.R21D06, Scer\GAL4^DBD.R23B09

Hsap\KCNJ2^5XUAS.EGFP

memory defective | larval stage, with Hsap\RELA^AD.R89G07, Scer\GAL4^DBD.R24E12

Hsap\KCNJ2^5XUAS.EGFP

memory defective | larval stage | nutrition conditional, with Hsap\RELA^AD.R76F05, Scer\GAL4^DBD.R95H02

Hsap\KCNJ2^5XUAS.EGFP

neuroanatomy defective, with Scer\GAL4^GMR.PF

Hsap\KCNJ2^UAS.EGFP

neuroanatomy defective, with Scer\GAL4^αTub84B.PP

Hsap\KCNJ2^UAS.EGFP

neuroanatomy defective | first instar larval stage, with Ecol\lexA^VP16.Orco

Hsap\KCNJ2^lexAop.EGFP

neuroanatomy defective | first instar larval stage, with Scer\GAL4^Lim3b

Hsap\KCNJ2^UAS.EGFP

neuroanatomy defective | larval stage, with Scer\GAL4^Orco.PU

Hsap\KCNJ2^UAS.EGFP

neuroanatomy defective | RU486 conditional, with Scer\GAL4^Pdf.Switch1a

Hsap\KCNJ2^UAS.EGFP

neuroanatomy defective | somatic clone, with Scer\FLP1^UAS.cUa, Scer\GAL4^Act.PU, Scer\GAL4^eve.RRK

Hsap\KCNJ2^UAS.EGFP

neuroanatomy defective | somatic clone, with Scer\GAL4^ppk.PU

Hsap\KCNJ2^UAS.GFP

neuroanatomy defective | third instar larval stage

Hsap\KCNJ2^UAS.EGFP

neuroanatomy defective | third instar larval stage, with Scer\GAL4^Mhc.PW

Hsap\KCNJ2^UAS.EGFP

neurophysiology defective, with Scer\GAL4^eve.RRC

Hsap\KCNJ2^UAS.EGFP

neurophysiology defective, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

neurophysiology defective, with Scer\GAL4^Trh.PB

Hsap\KCNJ2^UAS.EGFP

neurophysiology defective, with Scer\GAL4^unspecified

Hsap\KCNJ2^UAS.EGFP

neurophysiology defective | adult stage, with Hsap\RELA^AD.R19G02, Scer\GAL4^DBD.R75G12

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

neurophysiology defective | adult stage, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

neurophysiology defective | adult stage, with Hsap\RELA^AD.R48H08, Scer\GAL4^DBD.R29G11

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

neurophysiology defective | adult stage, with Scer\GAL4^GMR67E06

Hsap\KCNJ2^UAS.EGFP

neurophysiology defective | adult stage, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

neurophysiology defective | adult stage, with Scer\GAL4^ple.TH-C'

Hsap\KCNJ2^UAS.EGFP

neurophysiology defective | adult stage, with Scer\GAL4^{VGlut.VGN9281}

Hsap\KCNJ2^UAS.EGFP

neurophysiology defective | adult stage | conditional, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

neurophysiology defective | larval stage, with Scer\GAL4^Orco.PU

Hsap\KCNJ2^UAS.EGFP

neurophysiology defective | RU486 conditional, with Scer\GAL4^Pdf.Switch1a

Hsap\KCNJ2^UAS.EGFP

neurophysiology defective | somatic clone, with Scer\GAL4^ppk.PU

Hsap\KCNJ2^UAS.GFP

neurophysiology defective | third instar larval stage, with Scer\GAL4^Mhc.PW

Hsap\KCNJ2^UAS.EGFP

optomotor response defective | adult stage, with Scer\GAL4^GMR24E09

Hsap\KCNJ2^UAS.cUa.EGFP

optomotor response defective | adult stage, with Scer\GAL4^VT058487

Hsap\KCNJ2^UAS.cUa.EGFP

optomotor response defective | adult stage | conditional, with Hsap\RELA^AD.R11D03, Scer\GAL4^DBD.R19C10

Hsap\KCNJ2^UAS.EGFP

optomotor response defective | adult stage | conditional, with Hsap\RELA^AD.R11D03, Scer\GAL4^DBD.R61H02

Hsap\KCNJ2^UAS.EGFP

oviposition defective, with Ecol\lexA^Gr66a.PU, Ecol\lexA^VP16.Gr64f, Scer\GAL4^Ir76b.1.5, Scer\GAL80^{ts.lexAop.cTa}

Hsap\KCNJ2^UAS.EGFP

oviposition defective, with Scer\GAL4^Ir76b.1.5

Hsap\KCNJ2^UAS.EGFP

pain response defective | larval stage, with Ecol\lexA^p65.Ilp7.DP

Hsap\KCNJ2^lexAop.cHa

pain response defective | larval stage, with Hsap\RELA^AD.R82E12, Scer\GAL4^{DBD.Rab11.6.14.3}

Hsap\KCNJ2^UAS.EGFP

pain response defective | larval stage, with Scer\GAL4^19-12, Scer\GAL80^tsh-GAL80

Hsap\KCNJ2^UAS.EGFP

pain response defective | larval stage, with Scer\GAL4^1003.3, Scer\GAL80^tsh-GAL80

Hsap\KCNJ2^UAS.EGFP

pain response defective | larval stage, with Scer\GAL4^GMR82E12

Hsap\KCNJ2^UAS.EGFP

pain response defective | larval stage, with Scer\GAL4^Ilp7.PY

Hsap\KCNJ2^UAS.EGFP

pain response defective | larval stage, with Scer\GAL4^ppk.PG

Hsap\KCNJ2^UAS.EGFP

pain response defective | larval stage, with Scer\GAL4^Rab11.6.14.3

Hsap\KCNJ2^UAS.EGFP

paralytic | embryonic stage, with Scer\GAL4^elav-C155

Hsap\KCNJ2^UAS.EGFP

phototaxis defective, with Scer\GAL4^cry.PZ

Hsap\KCNJ2^UAS.EGFP

phototaxis defective, with Scer\GAL4^tim.PE

Hsap\KCNJ2^UAS.EGFP

phototaxis defective, with Scer\GAL4^tim.PE, Scer\GAL80^cry.PS

Hsap\KCNJ2^UAS.EGFP

phototaxis defective, with Scer\GAL4^tim.PE, Scer\GAL80^Pdf.PS

Hsap\KCNJ2^UAS.EGFP

phototaxis defective | third instar larval stage, with Scer\GAL4^GMR.PFa

Hsap\KCNJ2^UAS.EGFP

phototaxis defective | third instar larval stage, with Scer\GAL4^ppk.1.9

Hsap\KCNJ2^UAS.EGFP

proboscis extension reflex defective, with Scer\GAL4^E564

Hsap\KCNJ2^UAS.EGFP

proboscis extension reflex defective, with Scer\GAL4^Gr5a.8.5

Hsap\KCNJ2^UAS.EGFP

proboscis extension reflex defective | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

short lived, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

short lived, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

sleep defective, with Scer\GAL4^cry.PE, Scer\GAL80^Pdf.PS

Hsap\KCNJ2^UAS.EGFP

sleep defective, with Scer\GAL4^nur-Gal4

Hsap\KCNJ2^UAS.EGFP

smell perception defective, with Scer\GAL4^ey-OK107

Hsap\KCNJ2^UAS.EGFP

smell perception defective, with Scer\GAL4^GMR9A11

Hsap\KCNJ2^UAS.EGFP

smell perception defective, with Scer\GAL4^GMR10B08

Hsap\KCNJ2^UAS.EGFP

smell perception defective, with Scer\GAL4^GMR67B04

Hsap\KCNJ2^UAS.EGFP

some die during larval stage, with Scer\GAL4^dimm-929

Hsap\KCNJ2^UAS.EGFP

some die during larval stage, with Scer\GAL4^dimm-929, Scer\GAL80^CCAP.PL

Hsap\KCNJ2^UAS.EGFP

some die during pupal stage, with Scer\GAL4^Burs.PP

Hsap\KCNJ2^UAS.EGFP

some die during pupal stage | heat sensitive, with Scer\GAL4^Burs.PP, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

song defective, with Ecol\lexA^GMR13H01, Scer\FLP1^L.8xlexAop, Scer\GAL4^dsx.Δ2

Hsap\KCNJ2^{FRT.STOP.10x.UAS.GFP}

song defective | male limited | somatic clone, with Scer\GAL4^GMR21A01

Hsap\KCNJ2^10x.UAS.GFP

song defective | male limited | somatic clone, with Scer\GAL4^GMR73C03

Hsap\KCNJ2^10x.UAS.GFP

starvation stress response defective, with Scer\GAL4^AstA.2.1

Hsap\KCNJ2^UAS.EGFP

stress response defective, with Scer\GAL4^109-30

Hsap\KCNJ2^UAS.EGFP

stress response defective, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

stress response defective, with Scer\GAL4^NP0751

Hsap\KCNJ2^UAS.EGFP

stress response defective, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

tarsal response defective, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr64f.9.7, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

taste perception defective, with Scer\GAL4^E409

Hsap\KCNJ2^UAS.EGFP

taste perception defective, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

thermotaxis behavior defective, with Scer\GAL4^17d

Hsap\KCNJ2^UAS.EGFP

thermotaxis behavior defective, with Scer\GAL4^lilli-189Y

Hsap\KCNJ2^UAS.EGFP

thermotaxis behavior defective | adult stage | conditional, with Scer\GAL4^Ir40a.3011

Hsap\KCNJ2^UAS.EGFP

thermotaxis behavior defective | adult stage | heat sensitive, with Scer\GAL4^DAT.PL, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

thermotaxis behavior defective | adult stage | heat sensitive, with Scer\GAL4^ple.PF, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

touch perception defective | larval stage, with Scer\GAL4^ppk.PG

Hsap\KCNJ2^UAS.EGFP

touch response defective | larval stage, with Scer\GAL4^1003.3, Scer\GAL80^tsh-GAL80

Hsap\KCNJ2^UAS.EGFP

touch response defective | larval stage, with Scer\GAL4^ppk.PG

Hsap\KCNJ2^UAS.EGFP

uncoordinated | larval stage, with Hsap\RELA^AD.R45A08, Scer\GAL4^DBD.R83H09

Hsap\KCNJ2^UAS.EGFP

uncoordinated | larval stage, with Scer\GAL4^GMR83H09

Hsap\KCNJ2^UAS.EGFP

visible | heat sensitive, with Scer\GAL4^Burs.PP, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

visual behavior defective, with Scer\GAL4^GMR15B07

Hsap\KCNJ2^UAS.EGFP

visual behavior defective, with Scer\GAL4^GMR28D01

Hsap\KCNJ2^UAS.EGFP

visual behavior defective | adult stage, with Hsap\RELA^AD.R19G02, Scer\GAL4^DBD.R70G12

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

visual behavior defective | adult stage, with Hsap\RELA^AD.R27F02, Scer\GAL4^DBD.R19G02

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

visual behavior defective | adult stage, with Hsap\RELA^AD.R27F02, Scer\GAL4^DBD.R60D05

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

visual behavior defective | adult stage, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

Phenotype manifest in

Allele

A1-7 dorsal acute muscle 1, with Scer\GAL4^eve.RRC

Hsap\KCNJ2^UAS.EGFP

abdominal anterior ventral multidendritic neuron vdaa | somatic clone, with Scer\GAL4^ppk.PU

Hsap\KCNJ2^UAS.GFP

aCC neuron, with Scer\GAL4^eve.RRC

Hsap\KCNJ2^UAS.EGFP

adult anterior midgut, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

adult CSD interneuron, with Scer\GAL4^αTub84B.PP

Hsap\KCNJ2^UAS.EGFP

adult peritrophic membrane, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

adult proventriculus, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

Bolwig nerve, with Scer\GAL4^GMR.PF

Hsap\KCNJ2^UAS.EGFP

class IV dendritic arborizing neuron, with Scer\GAL4^ppk.PU

Hsap\KCNJ2^UAS.GFP

dendrite | somatic clone, with Scer\FLP1^UAS.cUa, Scer\GAL4^Act.PU, Scer\GAL4^eve.RRK

Hsap\KCNJ2^UAS.EGFP

dorsal medial indirect flight muscle, with Scer\GAL4^GMR67E06

Hsap\KCNJ2^UAS.EGFP

dorsal medial indirect flight muscle, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

dorsal medial indirect flight muscle, with Scer\GAL4^ple.TH-C'

Hsap\KCNJ2^UAS.EGFP

dorsal medial indirect flight muscle | adult stage, with Scer\GAL4^{VGlut.VGN9281}

Hsap\KCNJ2^UAS.EGFP

embryonic/larval hindgut, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

embryonic/larval hindgut, with Scer\GAL4^P2.4.Pdf, Scer\GAL4^eve.RN2

Hsap\KCNJ2^UAS.EGFP

embryonic/larval muscle system, with Scer\GAL4^Mhc.PW

embryonic/larval neuromuscular junction | first instar larval stage | heat sensitive, with Scer\GAL4^Tdc2.PC, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

embryonic/larval neuromuscular junction | third instar larval stage, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

embryonic/larval olfactory receptor neuron, with Scer\GAL4^Orco.PU

Hsap\KCNJ2^UAS.EGFP

embryonic/larval olfactory receptor neuron | first instar larval stage, with Ecol\lexA^VP16.Orco

Hsap\KCNJ2^lexAop.EGFP

embryonic/larval olfactory receptor neuron | first instar larval stage, with Scer\GAL4^Lim3b

Hsap\KCNJ2^UAS.EGFP

female reproductive system, with Scer\GAL4^Ilp7.PC

Hsap\KCNJ2^UAS.EGFP

female reproductive system | RU486 conditional, with Scer\GAL4^{ppk.Switch.PR}

Hsap\KCNJ2^UAS.EGFP

giant fiber neuron, with Hsap\RELA^AD.R19G02, Scer\GAL4^DBD.R75G12

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

giant fiber neuron, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

giant fiber neuron, with Hsap\RELA^AD.R48H08, Scer\GAL4^DBD.R29G11

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

giant fiber neuron | conditional, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

intestinal stem cell, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

larval head, with Scer\GAL4^CCAP.PP

Hsap\KCNJ2^UAS.EGFP

larval head | chemical conditional, with Scer\GAL4^odd-MC

Hsap\KCNJ2^UAS.EGFP

larval LN period neuron, with Scer\GAL4^GMR.PF

Hsap\KCNJ2^UAS.EGFP

leg, with Scer\GAL4^CCAP.PP

Hsap\KCNJ2^UAS.EGFP

lipid droplet | adult stage, with Scer\GAL4^VT030604

Hsap\KCNJ2^UAS.EGFP

l-LNv neuron, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

l-LNv neuron | RU486 conditional, with Scer\GAL4^Pdf.Switch1a

Hsap\KCNJ2^UAS.EGFP

LNv neuron | third instar larval stage, with Scer\GAL4^unspecified

Hsap\KCNJ2^UAS.EGFP

Malpighian tubule, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

multidendritic neuron, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

multidendritic neuron | heat sensitive, with Scer\GAL4^Tdc2.PC, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

NMJ bouton, with Scer\GAL4^Mhc.PW

Hsap\KCNJ2^UAS.EGFP

photoreceptor cell, with Scer\GAL4^ninaE.PT

Hsap\KCNJ2^UAS.EGFP

proboscis, with Scer\GAL4^E564

Hsap\KCNJ2^UAS.EGFP

proboscis, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

projection neuron | larval stage, with Scer\GAL4^Orco.PU

Hsap\KCNJ2^UAS.EGFP

protocerebrum | RU486 conditional, with Scer\GAL4^Pdf.Switch1a

Hsap\KCNJ2^UAS.EGFP

RP2 motor neuron | somatic clone, with Scer\FLP1^UAS.cUa, Scer\GAL4^Act.PU, Scer\GAL4^eve.RRK

Hsap\KCNJ2^UAS.EGFP

type I bouton, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

type II bouton, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

type II bouton | first instar larval stage | heat sensitive, with Scer\GAL4^Tdc2.PC, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

ventral nerve cord | embryonic stage, with Scer\GAL4^elav-C155

Hsap\KCNJ2^UAS.EGFP

wing, with Scer\GAL4^CCAP.PP

Hsap\KCNJ2^UAS.EGFP

wing | adult stage A1, with Scer\GAL4^Burs.PP

Hsap\KCNJ2^UAS.EGFP

wing | adult stage A1 | heat sensitive, with Scer\GAL4^Burs.PP, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v7.1)

Homo sapiens (Human) (0)

No records found.

Model Organism Orthologs (via DIOPT v7.1)

Drosophila melanogaster (Fruit fly) (3)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Irk1

10 of 15

Yes

Irk2

10 of 15

Yes

Irk3

3 of 15

Yes

Ortholog(s) in Drosophila melanogaster (via OrthoDB v9.1) ( None identified )

No D. melanogaster orthologies identified

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

Cytogenetic map

Sequence location

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (5)

Bloomington

6595

w^*; P{UAS-Hsap\KCNJ2.EGFP}7

6596

w^*; P{UAS-Hsap\KCNJ2.EGFP}1

67686

w^*; P{UAS(FRT.stop)Hsap\KCNJ2}VIE-19A/CyO

Kyoto

108845

w^*; P{UAS-Hsap\KCNJ2.EGFP}7

108846

w^*; P{UAS-Hsap\KCNJ2.EGFP}1

Genomic Clones (0)

cDNA Clones (0)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequences

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Additional comments

FlyBase curator comment: Name changed to reflect current HGNC name (19th Nov. 2012).

(FlyBase Curators, 1992-)

Other Comments

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 6 )

Other crossreferences

Ensembl_Homo_sapiens -

ENSG00000123700

HUGO Gene Nomenclature Committee -

KCNJ2; potassium inwardly rectifying channel subfamily J member 2

Online Mendelian Inheritance in Man (OMIM) -

600681

Online Mendelian Inheritance in Man (OMIM) -

Synonyms and Secondary IDs (17)

Reported As

Symbol Synonym

Hsap\KCNJ2

IRK1

(HGNC Curators and FlyBase Curators, 2013-)

KCNJ2

(HGNC Curators and FlyBase Curators, 2013-)

KIR2.1

(Dickson, 2017.4.25)

Kir

(Head et al., 2015)

Kir 2.1

(Suster et al., 2003)

Kir1.2

(Garbe et al., 2016)

Kir2

(Dahal et al., 2017)

Kir2.1

(Goodman et al., 2018, Strother et al., 2018, Brown et al., 2017, Hattori et al., 2017, Kim et al., 2017, Tsubouchi et al., 2017, Burn et al., 2015, Hoopfer et al., 2015, Seidner et al., 2015, Galili et al., 2014, von Reyn et al., 2014, HGNC Curators and FlyBase Curators, 2013-, Jiang et al., 2013, Maisak et al., 2013, Shirangi et al., 2013, Yamanaka et al., 2013, Marella et al., 2012, Sitaraman et al., 2012, Suver et al., 2012, Cognigni et al., 2011, King et al., 2011, Ofstad et al., 2011, Yuan et al., 2011, Wang and Anderson, 2010, Claridge-Chang et al., 2009, Dankert et al., 2009, Yang et al., 2009, Hong et al., 2008, Fischler et al., 2007, Hardie et al., 2007, Roy et al., 2007, Joiner et al., 2006, Luan et al., 2006, Nitabach et al., 2006, Hardie et al., 2004, Hardie et al., 2002, Malpel et al., 2002, Nitabach et al., 2002, Hardie et al., 2001, Paradis et al., 2001, Paradis et al., 2001)

Kir_2.1

(Baines et al., 2001)

LQT7

(HGNC Curators and FlyBase Curators, 2013-)

kir2.1

(Ni et al., 2019, Spéder and Brand, 2014, Shirangi et al., 2013, Depetris-Chauvin et al., 2011, López-Arias et al., 2011)

Name Synonyms

Kir2.1

(Kim et al., 2018)

Potassium channel, inwardly rectifying, subfamily J

inward rectifier K+ channel

(Head et al., 2015)

inwardly rectifying K+ channel, Kir2.1

(Shirangi et al., 2013)

potassium inwardly rectifying channel subfamily J member 2

(HGNC Curators and FlyBase Curators, 2013-)

potassium inwardly-rectifying channel, subfamily J, member 2

(HGNC Curators and FlyBase Curators, 2013-)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (181)

Report Sections

Open Close