FlyBase Gene Report: Hsap\KCNJ2

General Information

Symbol

Hsap\KCNJ2

Species

H. sapiens

Name

potassium inwardly-rectifying channel, subfamily J, member 2

Annotation Symbol

Feature Type

engineered_foreign_gene

FlyBase ID

FBgn0044439

Gene Model Status

Not Applicable

Stock Availability

7 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Interactive Fly

Also Known As

Kir2.1, KCNJ2, Kir

Key Links

Tag or Foreign Gene Data

Foreign sequence; species == Homo sapiens; gene == KCNJ2; HGNC:6263.

(FlyBase Curators, 1992-)

Function

Information on product gene function for non-D. melanogaster species is no longer provided by FlyBase.

Up-to-date information on gene product function can be found by searching UniProtKB for proteins or RNAcentral for non-coding RNAs.

Summaries

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure New Section

Comments on Gene Model

Sequence Ontology: Class of Gene

engineered_foreign_gene

Transcript Data

Annotated Transcripts

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Polypeptides with Identical Sequences

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Hsap\KCNJ2 using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that the Fly Cell Atlas project found the gene expressed in that cell type. Darker colors mean that more cells of that cell type express the gene:

low

high

Colorless tiles indicate that there is no scRNAseq data for the gene in that cell type.

Colored tiles in ribbon indicate that expression data (RNA and/or protein) has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

Colored tiles in the ribbon indicate the average RNA expression level of the gene at the indicated stages:

low

high

as determined by RNA-seq (RPKM) using whole organism samples modENCODE, Brown et al., 2014. For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Hsap\KCNJ2 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Hsap\KCNJ2

View exonic expression by tissue for Hsap\KCNJ2

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 0 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 32 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Hsap\KCNJ2

Transgenic constructs containing regulatory region of Hsap\KCNJ2

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 0 )

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Alp4-c232

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^DAT.PL

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^dimm-929

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^elav-C155

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^ey-OK107

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^GH86

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^GH146

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^GMR78G02

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^GMR.PF

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^H24

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^Ilp2.215-3

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^Mef2.247

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^Mz520

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^NP6510

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^NP6561

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^OK348

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^R6

Hsap\KCNJ2^UAS.EGFP

lethal, with Scer\GAL4^Tab2-201Y

Hsap\KCNJ2^UAS.EGFP

lethal - all die before end of larval stage, with Scer\GAL4^dimm-929

Hsap\KCNJ2^UAS.EGFP

lethal - all die before end of larval stage, with Scer\GAL4^dimm-929, Scer\GAL80^CCAP.PL

Hsap\KCNJ2^UAS.EGFP

partially lethal - majority die, with Scer\GAL4^Burs.PP

Hsap\KCNJ2^UAS.EGFP

partially lethal - majority die | heat sensitive, with Scer\GAL4^Burs.PP, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

Sterility

Allele

female sterile, with Scer\GAL4^Ilp7.PY

Hsap\KCNJ2^UAS.EGFP

female sterile, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

male sterile, with Scer\GAL4^Crz.391

Hsap\KCNJ2^UAS.EGFP

male sterile, with Scer\GAL4^CrzR.3.5

Hsap\KCNJ2^UAS.EGFP

male sterile, with Scer\GAL4^Trh.1.0

Hsap\KCNJ2^UAS.EGFP

Other Phenotypes

Allele

abnormal behavior, with Scer\FLP1^fru, Scer\GAL4^5-HT1B.PY

Hsap\KCNJ2^UAS.GFP

abnormal behavior, with Scer\GAL4^5-HT1B.PY

Hsap\KCNJ2^UAS.EGFP

abnormal behavior, with Scer\GAL4^ppk29.3.612

Hsap\KCNJ2^UAS.EGFP

abnormal behavior, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

abnormal behavior | adult stage, with Ecol\lexA^fru.P1, Scer\GAL4^Tk

Hsap\KCNJ2^UAS.EGFP.cDa

abnormal behavior | adult stage, with Scer\GAL4^GMR22C06

Hsap\KCNJ2^UAS.EGFP

abnormal behavior | adult stage, with Scer\GAL4^GMR24G07

Hsap\KCNJ2^UAS.EGFP

abnormal behavior | adult stage, with Scer\GAL4^NPF.1

Hsap\KCNJ2^UAS.EGFP

abnormal behavior | RU486 conditional, with Scer\GAL4^{Mef2.247.Switch}

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr61a.4.9, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr64f.9.7, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL4^NP0534, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^4.64

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^10.229

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^17d

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^GMR79D04

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^Gr5a.8.5

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^Gr33a-GAL4

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^Gr61a.4.9

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^Gr64e.8

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^Gr64f.9.7

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^{Orco.2.642.Hsim\VP22}

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage, with Scer\GAL4^TrpA1.PR

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage | female limited, with Ecol\lexA^Gr66a.PS, Ecol\lexA^VP16.Gr64f, Scer\GAL4^Ir76b.1.5, Scer\GAL80^{ts.lexAop.cTa}

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage | female limited, with Scer\GAL4^Ir76b.1.5

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | adult stage | nutrition conditional, with Scer\GAL4^GMR38H02

Hsap\KCNJ2^UAS.cUa.EGFP

abnormal chemosensitive behavior | adult stage | nutrition conditional, with Scer\GAL4^SLC5A11.1.1

Hsap\KCNJ2^UAS.cUa.EGFP

abnormal chemosensitive behavior | larval stage, with Hsap\RELA^AD.R48F09, Scer\GAL4^DBD.R27A11

Hsap\KCNJ2^5XUAS.EGFP

abnormal chemosensitive behavior | larval stage, with Scer\GAL4^Ir60c.PC

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | larval stage, with Scer\GAL4^odd-MC

Hsap\KCNJ2^UAS.EGFP

abnormal chemosensitive behavior | larval stage | conditional, with Hsap\RELA^AD.R14E06, Scer\GAL4^DBD.R27G01

Hsap\KCNJ2^5XUAS.EGFP

abnormal circadian behavior | adult stage, with Scer\GAL4^S3.Hug

Hsap\KCNJ2^UAS.EGFP

abnormal circadian rhythm | oogenesis, with Scer\GAL4^VP16.CNMa

Hsap\KCNJ2^UAS.EGFP

abnormal copulation, with Scer\FLP1^fru, Scer\GAL4^VGlut-OK371, Scer\GAL80^{tsh-md621-GAL80}

Hsap\KCNJ2^{FRT.Stop.UAS.EGFP}

abnormal copulation | adult stage, with Scer\GAL4^{VGlut.VGN9281}

Hsap\KCNJ2^UAS.EGFP

abnormal courtship behavior, with Scer\FLP1^fru, Scer\GAL4^VGlut-OK371, Scer\GAL80^{tsh-md621-GAL80}

Hsap\KCNJ2^{FRT.Stop.UAS.EGFP}

abnormal courtship behavior, with Scer\GAL4^NPF.1

Hsap\KCNJ2^UAS.EGFP

abnormal courtship behavior | adult stage | male limited, with Scer\GAL4^{VGlut.VGN9281}

Hsap\KCNJ2^UAS.EGFP

abnormal developmental rate | larval stage, with Scer\GAL4^Ptth.cMa

Hsap\KCNJ2^UAS.EGFP

abnormal eclosion rhythm, with Scer\GAL4^Ptth.cMa

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage, with Ecol\lexA^GMR65C11, Scer\GAL4^Gr28b.b.4.7, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.cUa.EGFP

abnormal feeding behavior | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL4^NP0534, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL4^VT005008, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage, with Scer\GAL4^0098-G4

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage, with Scer\GAL4^0179-G4

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage, with Scer\GAL4^0301-G4

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage, with Scer\GAL4^Ae2-0178-G4

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage, with Scer\GAL4^Gr28b.b.4.7

Hsap\KCNJ2^UAS.cUa.EGFP

abnormal feeding behavior | adult stage, with Scer\GAL4^NP1562

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage, with Scer\GAL4^{Sema1a-0156-G4}

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage, with Scer\GAL4^SLC5A11.1.1

Hsap\KCNJ2^UAS.cUa.EGFP

abnormal feeding behavior | adult stage, with Scer\GAL4^tara-0116-G4

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage | heat sensitive, with Scer\GAL4^Alp4-c232

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage | heat sensitive, with Scer\GAL4^GMR15B07

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage | heat sensitive, with Scer\GAL4^GMR38H02

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage | heat sensitive, with Scer\GAL4^SLC5A11.1.1

Hsap\KCNJ2^UAS.EGFP

abnormal feeding behavior | adult stage | nutrition conditional, with Scer\GAL4^Dh44.PU

Hsap\KCNJ2^UAS.EGFP

abnormal flight, with Scer\GAL4^Trh.PB

Hsap\KCNJ2^UAS.EGFP

abnormal heat stress response | larval stage, with Scer\GAL4^ppk.PG

Hsap\KCNJ2^UAS.EGFP

abnormal jump response, with Hsap\RELA^AD.R19G02, Scer\GAL4^DBD.R75G12

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal jump response | adult stage, with Hsap\RELA^AD.R17A04, Scer\GAL4^DBD.R68A06

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal jump response | adult stage, with Hsap\RELA^AD.R17A04, Scer\GAL4^DBD.R79H02

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal jump response | adult stage, with Hsap\RELA^AD.R48H08, Scer\GAL4^DBD.R29G11

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal jump response | adult stage | conditional, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal jump response | adult stage | conditional, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R86D05

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal jump response | adult stage | conditional, with Hsap\RELA^AD.R49C04, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal locomotor behavior | adult stage, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr61a.4.9, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr64f.9.7, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Hsap\RELA^AD.R19G02, Scer\GAL4^DBD.R70G12

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal locomotor behavior | adult stage, with Hsap\RELA^AD.R27F02, Scer\GAL4^DBD.R19G02

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal locomotor behavior | adult stage, with Hsap\RELA^AD.R27F02, Scer\GAL4^DBD.R60D05

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal locomotor behavior | adult stage, with Scer\GAL4^238Y

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^E564

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^GMR30G08

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^GMR38E07

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^GMR49H02

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^GMR79D04

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^GMR85A11

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^GMR89E07

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^Gr5a.8.5

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^Gr61a.4.9

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^Gr64e.8

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^Gr64f.9.7

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^iav.PK

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^NP0895

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^NP1619

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^NP3069

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^ple.PU

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage, with Scer\GAL4^Tdc2.PC

abnormal locomotor behavior | adult stage | heat sensitive, with Scer\GAL4^Ddc.HL9

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | adult stage | heat sensitive, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | larval stage, with Scer\GAL4^iav.PP

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | larval stage, with Scer\GAL4^odd-MC

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | larval stage, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | third instar larval stage, with Scer\GAL4^dimm-929

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor behavior | third instar larval stage | heat sensitive, with Scer\GAL4^elav.PLu, Scer\GAL80^{tsh-md621-GAL80}

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor rhythm, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor rhythm, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor rhythm | adult stage, with Hsap\RELA^AD.R12G04, Scer\GAL4^DBD.R18D09

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Dvir\Pdf.1.9

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor rhythm | adult stage, with Scer\GAL4^GMR65C07

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor rhythm | adult stage, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor rhythm | adult stage, with Scer\GAL80^Pdf.PS

Hsap\KCNJ2^UAS.EGFP

abnormal locomotor rhythm | RU486 conditional, with Scer\GAL4^Pdf.Switch1a

Hsap\KCNJ2^UAS.EGFP

abnormal mating behavior | male, with Scer\GAL4^{VP16.natalisin}

Hsap\KCNJ2^UAS.EGFP

abnormal mating behavior | male limited | somatic clone, with Scer\GAL4^GMR21A01

Hsap\KCNJ2^10x.UAS.GFP

abnormal memory | adult stage, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr64f.9.7, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^GMR18H09

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^GMR32G08

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^GMR66A09

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^GMR76B09

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^GMR76B09, Scer\GAL4^NP2397

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^GMR94F11

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^NP2397

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^NP2397, Scer\GAL80^ple.PK

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^NP2397, Scer\GAL80^R48B04

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^NP2397, Scer\GAL80^VGlut.PV

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^NP2758

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^NP7177

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^ple.TH-D'

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^ple.TH-F-3

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^Trh.PB

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^TrpA1.SH

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^VT026001

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^VT028152

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage, with Scer\GAL4^VT040039

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

abnormal memory | adult stage | RU486 conditional, with Scer\GAL4^{Mef2.247.Switch}

Hsap\KCNJ2^UAS.cUa.EGFP

abnormal memory | larval stage, with Hsap\RELA^AD.R21D02, Scer\GAL4^DBD.R55D08

Hsap\KCNJ2^5XUAS.EGFP

abnormal memory | larval stage, with Hsap\RELA^AD.R21D06, Scer\GAL4^DBD.R23B09

Hsap\KCNJ2^5XUAS.EGFP

abnormal memory | larval stage, with Hsap\RELA^AD.R89G07, Scer\GAL4^DBD.R24E12

Hsap\KCNJ2^5XUAS.EGFP

abnormal memory | larval stage | nutrition conditional, with Hsap\RELA^AD.R76F05, Scer\GAL4^DBD.R95H02

Hsap\KCNJ2^5XUAS.EGFP

abnormal neuroanatomy, with Scer\GAL4^GMR.PF

Hsap\KCNJ2^UAS.EGFP

abnormal neuroanatomy, with Scer\GAL4^αTub84B.PP

Hsap\KCNJ2^UAS.EGFP

abnormal neuroanatomy | first instar larval stage, with Ecol\lexA^VP16.Orco

Hsap\KCNJ2^lexAop.EGFP

abnormal neuroanatomy | first instar larval stage, with Scer\GAL4^Lim3b

Hsap\KCNJ2^UAS.EGFP

abnormal neuroanatomy | larval stage, with Scer\GAL4^Orco.PU

Hsap\KCNJ2^UAS.EGFP

abnormal neuroanatomy | RU486 conditional, with Scer\GAL4^Pdf.Switch1a

Hsap\KCNJ2^UAS.EGFP

abnormal neuroanatomy | somatic clone, with Scer\FLP1^UAS.cUa, Scer\GAL4^Act.PU, Scer\GAL4^eve.RRK

Hsap\KCNJ2^UAS.EGFP

abnormal neuroanatomy | somatic clone, with Scer\GAL4^ppk.PU

Hsap\KCNJ2^UAS.GFP

abnormal neuroanatomy | third instar larval stage

Hsap\KCNJ2^UAS.EGFP

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^Mhc.PW

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology, with Scer\GAL4^eve.RRC

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology, with Scer\GAL4^Trh.PB

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology, with Scer\GAL4^unspecified

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology | adult stage, with Hsap\RELA^AD.R19G02, Scer\GAL4^DBD.R75G12

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal neurophysiology | adult stage, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal neurophysiology | adult stage, with Hsap\RELA^AD.R48H08, Scer\GAL4^DBD.R29G11

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal neurophysiology | adult stage, with Scer\GAL4^{CG42260-MB01043}

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology | adult stage, with Scer\GAL4^GMR67E06

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology | adult stage, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology | adult stage, with Scer\GAL4^ple.TH-C'

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology | adult stage, with Scer\GAL4^{VGlut.VGN9281}

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology | adult stage | conditional, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal neurophysiology | larval stage, with Scer\GAL4^Orco.PU

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology | RU486 conditional, with Scer\GAL4^Pdf.Switch1a

Hsap\KCNJ2^UAS.EGFP

abnormal neurophysiology | somatic clone, with Scer\GAL4^ppk.PU

Hsap\KCNJ2^UAS.GFP

abnormal neurophysiology | third instar larval stage, with Scer\GAL4^Mhc.PW

Hsap\KCNJ2^UAS.EGFP

abnormal optomotor response | adult stage, with Scer\GAL4^GMR24E09

Hsap\KCNJ2^UAS.cUa.EGFP

abnormal optomotor response | adult stage, with Scer\GAL4^VT058487

Hsap\KCNJ2^UAS.cUa.EGFP

abnormal optomotor response | adult stage | conditional, with Hsap\RELA^AD.R11D03, Scer\GAL4^DBD.R19C10

Hsap\KCNJ2^UAS.EGFP

abnormal optomotor response | adult stage | conditional, with Hsap\RELA^AD.R11D03, Scer\GAL4^DBD.R61H02

Hsap\KCNJ2^UAS.EGFP

abnormal oviposition, with Ecol\lexA^Gr66a.PS, Ecol\lexA^VP16.Gr64f, Scer\GAL4^Ir76b.1.5, Scer\GAL80^{ts.lexAop.cTa}

Hsap\KCNJ2^UAS.EGFP

abnormal oviposition, with Ecol\lexA^VP16.Gr5a

Hsap\KCNJ2^lexAop.cHa

abnormal oviposition, with Ecol\lexA^VP16.Gr64f

Hsap\KCNJ2^lexAop.cHa

abnormal oviposition, with Scer\GAL4^Gr64a-GAL4

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal oviposition, with Scer\GAL4^Ir76b.1.5

Hsap\KCNJ2^UAS.EGFP

abnormal oviposition, with Scer\GAL4^Tmc.3.0, Scer\GAL80^VGlut.PV

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal oviposition | chemical conditional, with Scer\GAL4^Gr5a.8.5

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal oviposition | chemical conditional, with Scer\GAL4^Gr64f.9.7

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal oviposition | chemical conditional, with Scer\GAL4^Tmc.3.0

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal pain response | larval stage, with Ecol\lexA^p65.Ilp7.DP

Hsap\KCNJ2^lexAop.cHa

abnormal pain response | larval stage, with Hsap\RELA^AD.R82E12, Scer\GAL4^{DBD.Rab11.6.14.3}

Hsap\KCNJ2^UAS.EGFP

abnormal pain response | larval stage, with Scer\GAL4^19-12, Scer\GAL80^{tsh-md621-GAL80}

Hsap\KCNJ2^UAS.EGFP

abnormal pain response | larval stage, with Scer\GAL4^1003.3, Scer\GAL80^{tsh-md621-GAL80}

Hsap\KCNJ2^UAS.EGFP

abnormal pain response | larval stage, with Scer\GAL4^GMR82E12

Hsap\KCNJ2^UAS.EGFP

abnormal pain response | larval stage, with Scer\GAL4^Ilp7.PY

Hsap\KCNJ2^UAS.EGFP

abnormal pain response | larval stage, with Scer\GAL4^ppk.PG

Hsap\KCNJ2^UAS.EGFP

abnormal pain response | larval stage, with Scer\GAL4^Rab11.6.14.3

Hsap\KCNJ2^UAS.EGFP

abnormal phototaxis, with Scer\GAL4^cry.PZ

Hsap\KCNJ2^UAS.EGFP

abnormal phototaxis, with Scer\GAL4^tim.PE

Hsap\KCNJ2^UAS.EGFP

abnormal phototaxis, with Scer\GAL4^tim.PE, Scer\GAL80^cry.PS

Hsap\KCNJ2^UAS.EGFP

abnormal phototaxis, with Scer\GAL4^tim.PE, Scer\GAL80^Pdf.PS

Hsap\KCNJ2^UAS.EGFP

abnormal phototaxis | third instar larval stage, with Scer\GAL4^GMR.PFa

Hsap\KCNJ2^UAS.EGFP

abnormal phototaxis | third instar larval stage, with Scer\GAL4^ppk.1.9

Hsap\KCNJ2^UAS.EGFP

abnormal proboscis extension reflex, with Scer\GAL4^E564

Hsap\KCNJ2^UAS.EGFP

abnormal proboscis extension reflex, with Scer\GAL4^Gr5a.8.5

Hsap\KCNJ2^UAS.EGFP

abnormal proboscis extension reflex | adult stage, with Scer\FLP1^276B, Scer\GAL4^0098-G4, Scer\GAL80^αTub84B.PG

Hsap\KCNJ2^UAS.EGFP

abnormal sleep, with Scer\GAL4^cry.PE, Scer\GAL80^Pdf.PS

Hsap\KCNJ2^UAS.EGFP

abnormal sleep, with Scer\GAL4^nur-Gal4

Hsap\KCNJ2^UAS.EGFP

abnormal sleep | adult stage, with Scer\GAL4^{CCHa1-2A-GAL4}

Hsap\KCNJ2^UAS.EGFP

abnormal sleep | adult stage, with Scer\GAL4^Tk-2A-GAL4

Hsap\KCNJ2^UAS.EGFP

abnormal smell perception, with Scer\GAL4^ey-OK107

Hsap\KCNJ2^UAS.EGFP

abnormal smell perception, with Scer\GAL4^GMR9A11

Hsap\KCNJ2^UAS.EGFP

abnormal smell perception, with Scer\GAL4^GMR10B08

Hsap\KCNJ2^UAS.EGFP

abnormal smell perception, with Scer\GAL4^GMR67B04

Hsap\KCNJ2^UAS.EGFP

abnormal smell perception | adult stage, with Scer\GAL4^{CG42260-MB01043}

Hsap\KCNJ2^UAS.EGFP

abnormal song, with Ecol\lexA^GMR13H01, Scer\FLP1^L.8xlexAop, Scer\GAL4^dsx.Δ2

Hsap\KCNJ2^{FRT.STOP.10x.UAS.GFP}

abnormal song | male limited | somatic clone, with Scer\GAL4^GMR21A01

Hsap\KCNJ2^10x.UAS.GFP

abnormal song | male limited | somatic clone, with Scer\GAL4^GMR73C03

Hsap\KCNJ2^10x.UAS.GFP

abnormal starvation stress response, with Scer\GAL4^AstA.2.1

Hsap\KCNJ2^UAS.EGFP

abnormal stress response, with Scer\GAL4^109-30

Hsap\KCNJ2^UAS.EGFP

abnormal stress response, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

abnormal stress response, with Scer\GAL4^NP0751

Hsap\KCNJ2^UAS.EGFP

abnormal stress response, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

abnormal tarsal response, with Ecol\lexA^{VP16.Gr5a.cGa}, Scer\GAL4^Gr64f.9.7, Scer\GAL80^{IVS.WPRE.8xlexAop}

Hsap\KCNJ2^UAS.EGFP

abnormal taste perception, with Scer\GAL4^E409

Hsap\KCNJ2^UAS.EGFP

abnormal taste perception, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

abnormal thermotaxis, with Scer\GAL4^17d

Hsap\KCNJ2^UAS.EGFP

abnormal thermotaxis, with Scer\GAL4^lilli-189Y

Hsap\KCNJ2^UAS.EGFP

abnormal thermotaxis | adult stage | conditional, with Scer\GAL4^Ir40a.3011

Hsap\KCNJ2^UAS.EGFP

abnormal thermotaxis | adult stage | heat sensitive, with Scer\GAL4^DAT.PL, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

abnormal thermotaxis | adult stage | heat sensitive, with Scer\GAL4^ple.PF, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

abnormal touch perception | larval stage, with Scer\GAL4^ppk.PG

Hsap\KCNJ2^UAS.EGFP

abnormal touch response | larval stage, with Scer\GAL4^1003.3, Scer\GAL80^{tsh-md621-GAL80}

Hsap\KCNJ2^UAS.EGFP

abnormal touch response | larval stage, with Scer\GAL4^ppk.PG

Hsap\KCNJ2^UAS.EGFP

abnormal visual behavior, with Scer\GAL4^GMR15B07

Hsap\KCNJ2^UAS.EGFP

abnormal visual behavior, with Scer\GAL4^GMR28D01

Hsap\KCNJ2^UAS.EGFP

abnormal visual behavior | adult stage, with Hsap\RELA^AD.R19G02, Scer\GAL4^DBD.R70G12

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal visual behavior | adult stage, with Hsap\RELA^AD.R27F02, Scer\GAL4^DBD.R19G02

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal visual behavior | adult stage, with Hsap\RELA^AD.R27F02, Scer\GAL4^DBD.R60D05

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

abnormal visual behavior | adult stage, with Scer\GAL4^Alp4-c232

Hsap\KCNJ2^AAE.UAS.EGFP

abnormal visual behavior | adult stage, with Scer\GAL4^GMR15B07

Hsap\KCNJ2^AAE.UAS.EGFP

abnormal visual behavior | adult stage, with Scer\GAL4^GMR38H02

Hsap\KCNJ2^AAE.UAS.EGFP

abnormal visual behavior | adult stage, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

chemical resistant, with Scer\GAL4^Crz.PU

Hsap\KCNJ2^UAS.EGFP

chemical resistant, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

flightless, with Scer\GAL4^GMR67E06

Hsap\KCNJ2^UAS.EGFP

flightless, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

flightless, with Scer\GAL4^ple.TH-C'

Hsap\KCNJ2^UAS.EGFP

flightless, with Scer\GAL4^{VGlut.VGN9281}

Hsap\KCNJ2^UAS.EGFP

hyperactive | larval stage, with Scer\GAL4^ppk.PG

Hsap\KCNJ2^UAS.EGFP

hyperactive | larval stage | chemical conditional, with Scer\GAL4^odd-MC

Hsap\KCNJ2^UAS.EGFP

hypoactive | adult stage, with Scer\GAL4^NP0895

Hsap\KCNJ2^UAS.EGFP

hypoactive | adult stage, with Scer\GAL4^S3.Hug

Hsap\KCNJ2^UAS.EGFP

hypoactive | larval stage, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

hypoactive | larval stage, with Scer\GAL4^P2.4.Pdf, Scer\GAL4^eve.RN2

Hsap\KCNJ2^UAS.EGFP

increased occurrence of cell division, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

paralytic | embryonic stage, with Scer\GAL4^elav-C155

Hsap\KCNJ2^UAS.EGFP

short lived, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

short lived, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

some die during larval stage, with Scer\GAL4^dimm-929

Hsap\KCNJ2^UAS.EGFP

some die during larval stage, with Scer\GAL4^dimm-929, Scer\GAL80^CCAP.PL

Hsap\KCNJ2^UAS.EGFP

some die during pupal stage, with Scer\GAL4^Burs.PP

Hsap\KCNJ2^UAS.EGFP

some die during pupal stage | heat sensitive, with Scer\GAL4^Burs.PP, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

uncoordinated | larval stage, with Hsap\RELA^AD.R45A08, Scer\GAL4^DBD.R83H09

Hsap\KCNJ2^UAS.EGFP

uncoordinated | larval stage, with Scer\GAL4^GMR83H09

Hsap\KCNJ2^UAS.EGFP

visible | heat sensitive, with Scer\GAL4^Burs.PP, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

Phenotype manifest in

Allele

abdominal anterior ventral multidendritic neuron vdaa | somatic clone, with Scer\GAL4^ppk.PU

Hsap\KCNJ2^UAS.GFP

aCC neuron, with Scer\GAL4^eve.RRC

Hsap\KCNJ2^UAS.EGFP

adult anterior midgut, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

adult CSD interneuron, with Scer\GAL4^αTub84B.PP

Hsap\KCNJ2^UAS.EGFP

adult Malpighian tubule, with Scer\GAL4^Dh44

Hsap\KCNJ2^UAS.EGFP

adult olfactory receptor neuron Or22, with Scer\GAL4^{CG42260-MB01043}

Hsap\KCNJ2^UAS.EGFP

adult peritrophic membrane, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

adult proventriculus, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

Bolwig nerve, with Scer\GAL4^GMR.PF

Hsap\KCNJ2^UAS.EGFP

dendrite | somatic clone, with Scer\FLP1^UAS.cUa, Scer\GAL4^Act.PU, Scer\GAL4^eve.RRK

Hsap\KCNJ2^UAS.EGFP

dorsal medial indirect flight muscle cell, with Scer\GAL4^GMR67E06

Hsap\KCNJ2^UAS.EGFP

dorsal medial indirect flight muscle cell, with Scer\GAL4^ple.PF

Hsap\KCNJ2^UAS.EGFP

dorsal medial indirect flight muscle cell, with Scer\GAL4^ple.TH-C'

Hsap\KCNJ2^UAS.EGFP

dorsal medial indirect flight muscle cell | adult stage, with Scer\GAL4^{VGlut.VGN9281}

Hsap\KCNJ2^UAS.EGFP

egg chamber | decreased number | oogenesis, with Scer\GAL4^VP16.CNMa

Hsap\KCNJ2^UAS.EGFP

embryonic/larval hindgut, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

embryonic/larval hindgut, with Scer\GAL4^P2.4.Pdf, Scer\GAL4^eve.RN2

Hsap\KCNJ2^UAS.EGFP

embryonic/larval muscle system, with Scer\GAL4^Mhc.PW

embryonic/larval neuromuscular junction | first instar larval stage | heat sensitive, with Scer\GAL4^Tdc2.PC, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

embryonic/larval neuromuscular junction | third instar larval stage, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

embryonic/larval olfactory receptor neuron, with Scer\GAL4^Orco.PU

Hsap\KCNJ2^UAS.EGFP

embryonic/larval olfactory receptor neuron | first instar larval stage, with Ecol\lexA^VP16.Orco

Hsap\KCNJ2^lexAop.EGFP

embryonic/larval olfactory receptor neuron | first instar larval stage, with Scer\GAL4^Lim3b

Hsap\KCNJ2^UAS.EGFP

female reproductive system, with Scer\GAL4^Ilp7.PC

Hsap\KCNJ2^UAS.EGFP

female reproductive system | RU486 conditional, with Scer\GAL4^{ppk.Switch.PR}

Hsap\KCNJ2^UAS.EGFP

giant fiber neuron, with Hsap\RELA^AD.R19G02, Scer\GAL4^DBD.R75G12

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

giant fiber neuron, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

giant fiber neuron, with Hsap\RELA^AD.R48H08, Scer\GAL4^DBD.R29G11

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

giant fiber neuron | conditional, with Hsap\RELA^AD.R47H03, Scer\GAL4^DBD.R72E01

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

intestinal stem cell, with Scer\GAL4^NP3253

Hsap\KCNJ2^UAS.EGFP

larval head, with Scer\GAL4^CCAP.PP

Hsap\KCNJ2^UAS.EGFP

larval head | chemical conditional, with Scer\GAL4^odd-MC

Hsap\KCNJ2^UAS.EGFP

larval LN period neuron, with Scer\GAL4^GMR.PF

Hsap\KCNJ2^UAS.EGFP

larval multidendritic class IV neuron, with Scer\GAL4^ppk.PU

Hsap\KCNJ2^UAS.GFP

larval ventral nerve cord | embryonic stage, with Scer\GAL4^elav-C155

Hsap\KCNJ2^UAS.EGFP

leg, with Scer\GAL4^CCAP.PP

Hsap\KCNJ2^UAS.EGFP

lipid droplet | adult stage, with Scer\GAL4^VT030604

Hsap\KCNJ2^UAS.EGFP

l-LNv neuron, with Scer\GAL4^P2.4.Pdf

Hsap\KCNJ2^UAS.EGFP

l-LNv neuron | RU486 conditional, with Scer\GAL4^Pdf.Switch1a

Hsap\KCNJ2^UAS.EGFP

LNv neuron | third instar larval stage, with Scer\GAL4^unspecified

Hsap\KCNJ2^UAS.EGFP

Malpighian tubule, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

multidendritic neuron, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

multidendritic neuron | heat sensitive, with Scer\GAL4^Tdc2.PC, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

muscle cell of A1-7 dorsal acute muscle 1, with Scer\GAL4^eve.RRC

Hsap\KCNJ2^UAS.EGFP

NMJ bouton, with Scer\GAL4^Mhc.PW

Hsap\KCNJ2^UAS.EGFP

photoreceptor neuron, with Scer\GAL4^ninaE.PT

Hsap\KCNJ2^UAS.EGFP

proboscis, with Scer\GAL4^E564

Hsap\KCNJ2^UAS.EGFP

proboscis, with Scer\GAL4^Lk.2.2

Hsap\KCNJ2^UAS.EGFP

projection neuron | larval stage, with Scer\GAL4^Orco.PU

Hsap\KCNJ2^UAS.EGFP

protocerebrum | RU486 conditional, with Scer\GAL4^Pdf.Switch1a

Hsap\KCNJ2^UAS.EGFP

RP2 motor neuron | somatic clone, with Scer\FLP1^UAS.cUa, Scer\GAL4^Act.PU, Scer\GAL4^eve.RRK

Hsap\KCNJ2^UAS.EGFP

type I bouton, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

type II bouton, with Scer\GAL4^Tdc2.PC

Hsap\KCNJ2^UAS.EGFP

type II bouton | first instar larval stage | heat sensitive, with Scer\GAL4^Tdc2.PC, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

wing, with Scer\GAL4^CCAP.PP

Hsap\KCNJ2^UAS.EGFP

wing | adult stage A1, with Scer\GAL4^Burs.PP

Hsap\KCNJ2^UAS.EGFP

wing | adult stage A1 | heat sensitive, with Scer\GAL4^Burs.PP, Scer\GAL80^ts.αTub84B

Hsap\KCNJ2^UAS.EGFP

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (0)

No records found.

Model Organism Orthologs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (3)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Irk1

9 of 15

Yes

Irk2

9 of 15

Yes

Irk3

3 of 15

Other Organism Orthologs (via OrthoDB)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

Cytogenetic map

Sequence location

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (7)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

91802

w^*; P{QUAS-Kir2.1.P}3/CyO

6595

w^*; P{UAS-Hsap\KCNJ2.EGFP}7

6596

w^*; P{UAS-Hsap\KCNJ2.EGFP}1

67686

w^*; P{UAS(FRT.stop)Hsap\KCNJ2}VIE-19A/CyO

92026

y¹ w^*; PBac{UAS-hKCNJ2.HA}VK00037

Kyoto

108845

w^*; P{UAS-Hsap\KCNJ2.EGFP}7

108846

w^*; P{UAS-Hsap\KCNJ2.EGFP}1

Genomic Clones (0)

cDNA Clones (0)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Additional comments

FlyBase curator comment: Name changed to reflect current HGNC name (19th Nov. 2012).

(FlyBase Curators, 1992-)

Other Comments

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 8 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

3759

Other crossreferences

Ensembl_Homo_sapiens -

ENSG00000123700

HUGO Gene Nomenclature Committee -

KCNJ2; potassium inwardly rectifying channel subfamily J member 2

MARRVEL - MARRVEL (human gene)

3759

Online Mendelian Inheritance in Man (OMIM) -

600681

Online Mendelian Inheritance in Man (OMIM) -

Synonyms and Secondary IDs (18)

Reported As

Symbol Synonym

Hsap\KCNJ2

IRK1

(HGNC Curators and FlyBase Curators, 2013-)

KCNJ2

(Celniker and Bellen, 2017-, HGNC Curators and FlyBase Curators, 2013-)

KIR2.1

(Dickson, 2017.4.25)

Kir

(Kohsaka et al., 2019, Head et al., 2015)

Kir 2.1

(Suster et al., 2003)

Kir1.2

(Garbe et al., 2016)

Kir2

(Dahal et al., 2017)

Kir2.1

(Barber et al., 2021, Bentzur et al., 2021, Nettnin et al., 2021, Vogt et al., 2021, Yuan et al., 2021, Chodankar et al., 2020, Choi et al., 2020, Goodman et al., 2018, Strother et al., 2018, Brown et al., 2017, Hattori et al., 2017, Kim et al., 2017, Tsubouchi et al., 2017, Burn et al., 2015, Hoopfer et al., 2015, Seidner et al., 2015, Galili et al., 2014, von Reyn et al., 2014, HGNC Curators and FlyBase Curators, 2013-, Jiang et al., 2013, Maisak et al., 2013, Shirangi et al., 2013, Yamanaka et al., 2013, Marella et al., 2012, Sitaraman et al., 2012, Suver et al., 2012, Cognigni et al., 2011, King et al., 2011, Ofstad et al., 2011, Yuan et al., 2011, Wang and Anderson, 2010, Claridge-Chang et al., 2009, Dankert et al., 2009, Yang et al., 2009, Hong et al., 2008, Fischler et al., 2007, Hardie et al., 2007, Roy et al., 2007, Joiner et al., 2006, Luan et al., 2006, Nitabach et al., 2006, Hardie et al., 2004, Hardie et al., 2002, Malpel et al., 2002, Nitabach et al., 2002, Hardie et al., 2001, Paradis et al., 2001, Paradis et al., 2001)

Kir_2.1

(Baines et al., 2001)

LQT7

(HGNC Curators and FlyBase Curators, 2013-)

kir-2.1

(Valdes-Aleman et al., 2021)

kir2.1

(Ni et al., 2019, Spéder and Brand, 2014, Shirangi et al., 2013, Depetris-Chauvin et al., 2011, López-Arias et al., 2011)

Name Synonyms

Kir2.1

(Kim et al., 2018)

Potassium channel, inwardly rectifying, subfamily J

inward rectifier K+ channel

(Head et al., 2015)

inwardly rectifying K+ channel, Kir2.1

(Shirangi et al., 2013)

potassium inwardly rectifying channel subfamily J member 2

(HGNC Curators and FlyBase Curators, 2013-)

potassium inwardly-rectifying channel, subfamily J, member 2

(HGNC Curators and FlyBase Curators, 2013-)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

References (289)

Information on product gene function for non-D. melanogaster species is no longer provided by FlyBase.

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