ATM, dATM, atm/tefu, ataxia telangiectasia mutated
Phosphatidylinositol 3- and 4-kinase - serves as Drosophila's ATM (ataxia telangiectasia mutated) - plays a conserved and essential role in the maintenance of normal telomeres and chromosome stability
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.48
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\tefu using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\tefu in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: tefu atm
Source for identity of atm CG6535 was sequence comparison ( date:040205 ).
tefu mutants show a high level of spontaneous telomere fusions in larval neuroblasts.
tefu is required for the maintenance of normal telomeres.
tefu mutants show a high level of spontaneous telomere fusions and other chromosome abnormalities in larval neuroblasts.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.