dSTIM, D-Stim, STIM1
Gene model reviewed during 5.50
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.39
Gene model reviewed during 5.55
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Stim using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Stim in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
S2R+ cells treated with dsRNA made from templates generated with primers against this gene show complete inhibition of thapsigargin-induced Ca2+ influx, but there is no effect on the filling state of Ca2+ stores.
dsRNA made from templates generated with primers against this gene used in a genome-wide dsRNA interference (RNAi) screen to identify regulators of the signalling pathway leading from Ca2+-calcineurin to NFAT.
Treatment of S2 cells with dsRNA made from templates generated with primers directed against this gene inhibits both the early and sustained components of Ca2+ entry evoked by thapsigargin at the single-cell level.