Gene model reviewed during 5.55
Gene model includes transcripts encoding non-overlapping portions of the full CDS.
Gene model reviewed during 5.43
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Gene model reviewed during 5.48
Gene model reviewed during 6.04
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\yuri using the Feature Mapper tool.
Western blot analysis reveals that different yuri protein isoforms are developmentally distributed. Only the 30 kDa isoform is maternally loaded into eggs. The 65 kDa isoforms are the most abundant in other tissues and in embryos. All isoform classes are observed in testis and in the thorax. Immunocytochemisty reveals that yuri protein present at all stages of spermatogenesis, peaking around meiosis, with most staining being cytoplasmic and diffuse. In post-meiotic spermatids, yuri protein accumulates in a cap over one hemisphere of each spermatid nucleus. As the nucleus elongates from the initial spherical shape, the yuri cap elongates into a stripe along the long axis of the nucleus; there is also a dot of immunoreactivity at the apical tip of the nucleus. In the final stages of spermatid nuclear maturation, the stripe disappears, leaving only the apical dot. By onset of actin cone formation, all yuri immunoreactivity is lost.
Comment: in axons that extend from antennal neurons to AMMC
GBrowse - Visual display of RNA-Seq signalsView Dmel\yuri in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Annotations CG11860 and CG12635 merged as CG31732 in release 3 of the genome annotation.
Termed 'yuri gagarin' because this gravitaxis defective mutant was identified on the 40th anniversary of the first manned space flight.
Called 'yuri' because a single amino acid polymorphism in this gene is uniquely present in strains showing strong negative gravitaxis and "this polymorphism was confirmed on the 40th anniversary of Gagarin's historic space flight, leading to the naming of the gene yuri, in his honour".